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Does Knockout of Arl4a in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Arl4a
cell proliferation
Embryonic Stem Cell Line
Gene: Arl4a (ADP-ribosylation factor-like 4A) Type: protein-coding Summary: Predicted to enable GTP binding activity. Acts upstream of or within brown fat cell differentiation. Located in nucleus. Is expressed in several structures, including central nervous system; jaw bone; paraxial mesenchyme; skelet...
Does Knockout of Camk1 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Camk1
protein/peptide distribution
myoblast cell line
Gene: Camk1 (calcium/calmodulin-dependent protein kinase I) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, intracellular signal transduction, nervous system development, nucleocytoplasmic transport, positive regulation of dendritic spine development...
Does Knockout of Kat8 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Kat8
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Kat8 (K(lysine) acetyltransferase 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, dosage compensation by inactivation of X chromosome, epigenetic regulation of gene expression, epithelial to mesenchymal transition, germ cell development, h...
Does Knockout of Rpl23 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Rpl23
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rpl23 (ribosomal protein L23) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G1 to G0 transition, cellular response to actinomycin D, cytoplasmic translation, negative regulation of transcription by RNA polymerase II, negative regulation of ubiquitin-dependent prot...
Does Knockout of Cd302 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Cd302
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cd302 (CD302 antigen) Type: protein-coding Summary: No summary available. Gene Ontology: BP: phagocytosis; MF: carbohydrate binding, signaling receptor activity; CC: cell cortex, cell projection, cytoplasm, filopodium, membrane, microvillus Pathways: UniProt: Q9DCG2 ...
Does Knockout of BC005537 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
BC005537
protein/peptide accumulation
Mouse cell
Gene: BC005537 (cDNA sequence BC005537) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q99LU8 Entrez ID: 79555
Does Knockout of Tysnd1 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Tysnd1
cell proliferation
Melanoma Cell Line
Gene: Tysnd1 (trypsin domain containing 1) Type: protein-coding Summary: This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also capable of remov...
Does Knockout of Nars2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Nars2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nars2 (asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)) Type: protein-coding Summary: Predicted to enable asparagine-tRNA ligase activity. Predicted to be involved in asparaginyl-tRNA aminoacylation. Located in mitochondrion. Is expressed in embryo; extraembryonic component; and primitive ...
Does Knockout of Szt2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Szt2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Szt2 (SZT2 subunit of KICSTOR complex) Type: protein-coding Summary: Involved in negative regulation of TORC1 signaling; regulation of superoxide dismutase activity; and response to nutrient levels. Acts upstream of or within central nervous system development; pigmentation; and post-embryonic dev...
Does Knockout of Izumo3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Izumo3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Izumo3 (IZUMO family member 3) Type: protein-coding Summary: Enables protein homodimerization activity. Involved in acrosome assembly. Located in inner acrosomal membrane. Orthologous to human IZUMO3 (IZUMO family member 3). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontolo...
Does Knockout of Eri2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Eri2
cell proliferation
Mouse kidney carcinoma cell
Gene: Eri2 (exoribonuclease 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: 3'-5'-RNA exonuclease activity, exonuclease activity, hydrolase activity, metal ion binding, nuclease activity, nucleic acid binding, zinc ion binding Pathways: UniProt: Q5BK...
Does Knockout of Mir16-1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Mir16-1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Mir16-1 (microRNA 16-1) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Tmem141 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Tmem141
protein/peptide distribution
myoblast cell line
Gene: Tmem141 (transmembrane protein 141) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A2AJB2 Entrez ID: 51875
Does Knockout of Tesmin in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Tesmin
protein/peptide distribution
myoblast cell line
Gene: Tesmin (testis expressed metallothionein like) Type: protein-coding Summary: Involved in male meiotic nuclear division and spermatogenesis. Located in cytoplasm and male germ cell nucleus. Is expressed in several structures, including adrenal gland; gonad; heart; liver; and lung. Orthologous to hu...
Does Knockout of Btbd35f13 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Btbd35f13
protein/peptide accumulation
Embryonic Cell Line
Gene: Btbd35f13 (BTB domain containing 35, family member 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, germ cell development Pathways: UniProt: B8JKF6 Entrez ID: 100040722
Does Knockout of Shank1 in Pancreatic Cell Line causally result in protein/peptide accumulation?
0
2,197
Knockout
Shank1
protein/peptide accumulation
Pancreatic Cell Line
Gene: Shank1 (SH3 and multiple ankyrin repeat domains 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: AMPA selective glutamate receptor signaling pathway, adult behavior, associative learning, cell differentiation, dendritic spine morphogenesis, determination of affect...
Does Knockout of Ecsit in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Ecsit
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ecsit (ECSIT signalling integrator) Type: protein-coding Summary: No summary available. Gene Ontology: BP: BMP signaling pathway, cell surface receptor protein serine/threonine kinase signaling pathway, immune system process, innate immune response, mesoderm formation, non-canonical NF-ka...
Does Knockout of Alox8 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Alox8
cell viability
Immortal mouse chromaffin cells
Gene: Alox8 (arachidonate 8-lipoxygenase) Type: protein-coding Summary: This gene belongs to the lipoxygenase (LOX) gene family whose members encode enzymes that catalyze the addition of molecular oxygen to polyunsaturated fatty acids (PUFAs) to yield fatty acid hydroperoxides. The encoded enzyme prefer...
Does Knockout of Ube2m in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Ube2m
cell proliferation
Mouse kidney carcinoma cell
Gene: Ube2m (ubiquitin-conjugating enzyme E2M) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of neuron apoptotic process, protein modification process, protein neddylation, regulation of postsynapse assembly; MF: ATP binding, NEDD8 conjugating enzyme...
Does Knockout of Ube2w in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Ube2w
protein/peptide distribution
myoblast cell line
Gene: Ube2w (ubiquitin-conjugating enzyme E2W (putative)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, TORC1 signaling, antiviral innate immune response, cellular response to misfolded protein, cellular response to nutrient levels, nega...
Does Knockout of Tubgcp3 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Tubgcp3
response to virus
Microglial Cell Line
Gene: Tubgcp3 (tubulin, gamma complex component 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic microtubule organization, meiotic cell cycle, microtubule cytoskeleton organization, microtubule nucleation, mitotic cell cycle, spindle assembly; MF: gamma-tubu...
Does Knockout of Ndufa5 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Ndufa5
cell proliferation
Mouse kidney carcinoma cell
Gene: Ndufa5 (NADH:ubiquinone oxidoreductase subunit A5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, proton motive force-driven mitochondrial ATP synthesis, respiratory electron transport chain; CC: membrane, mitochondrial inner membrane, mitochon...
Does Knockout of Clstn2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,174
Knockout
Clstn2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Clstn2 (calsyntenin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: associative learning, cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules, inhibitory synapse assembly, positive regulation of synapse assembly, positive regulation of ...
Does Knockout of Epha1 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Epha1
cell proliferation
Regulatory T cell
Gene: Epha1 (Eph receptor A1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, cell adhesion, cell surface receptor protein tyrosine kinase signaling pathway, ephrin receptor signaling pathway, negative regulation of cell migration, positive regulation of ang...
Does Knockout of Grip1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Grip1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Grip1 (glutamate receptor interacting protein 1) Type: protein-coding Summary: This gene encodes a protein containing multiple PDZ (post synaptic density protein, Drosophila disc large tumor suppressor, and zonula occludens-1 protein) domains. The encoded protein acts as a mediator between cytoske...
Does Knockout of Prph in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Prph
protein/peptide distribution
myoblast cell line
Gene: Prph (peripherin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoskeleton organization, intermediate filament cytoskeleton organization, intermediate filament organization; MF: protein binding, protein-containing complex binding, structural constituent of cytos...
Does Knockout of Tbca in Lymphoma Cell Line causally result in response to chemicals?
0
1,541
Knockout
Tbca
response to chemicals
Lymphoma Cell Line
Gene: Tbca (tubulin cofactor A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: post-chaperonin tubulin folding pathway, protein folding, tubulin complex assembly; MF: beta-tubulin binding, tubulin binding; CC: cytoplasm, cytoskeleton, microtubule, microtubule cytoskeleto...
Does Knockout of Atp6v1h in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Atp6v1h
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Atp6v1h (ATPase, H+ transporting, lysosomal V1 subunit H) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endocytosis, monoatomic ion transport, proton transmembrane transport, synaptic vesicle lumen acidification; CC: ATPase complex, clathrin-coated vesicle membran...
Does Knockout of A430033K04Rik in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
A430033K04Rik
cell viability
Immortal mouse chromaffin cells
Gene: A430033K04Rik (RIKEN cDNA A430033K04 gene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, regulation of DNA-templated transcription, regulation of macromolecule metabolic process, regulation of osteoblast differen...
Does Knockout of Nup54 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Nup54
cell proliferation
Mouse kidney carcinoma cell
Gene: Nup54 (nucleoporin 54) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NLS-bearing protein import into nucleus, mRNA transport, nuclear pore organization, nucleocytoplasmic transport, protein localization to nuclear inner membrane, protein targeting, protein transpo...
Does Knockout of Ccrl2 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Ccrl2
protein/peptide distribution
myoblast cell line
Gene: Ccrl2 (C-C motif chemokine receptor-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, calcium-mediated signaling, cell chemotaxis, chemokine-mediated signaling pathway, chemotaxis, immune response, inflammatory res...
Does Knockout of Ung in Lymphoma Cell Line causally result in response to chemicals?
0
1,545
Knockout
Ung
response to chemicals
Lymphoma Cell Line
Gene: Ung (uracil DNA glycosylase) Type: protein-coding Summary: Enables uracil DNA N-glycosylase activity. Acts upstream of or within isotype switching and somatic hypermutation of immunoglobulin genes. Located in mitochondrion and nucleus. Is expressed in several structures, including alimentary syste...
Does Knockout of Kif9 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Kif9
protein/peptide distribution
myoblast cell line
Gene: Kif9 (kinesin family member 9) Type: protein-coding Summary: Predicted to enable several functions, including ATP hydrolysis activity; identical protein binding activity; and microtubule motor activity. Involved in regulation of flagellated sperm motility. Located in sperm flagellum. Is expressed ...
Does Knockout of Il21 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Il21
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Il21 (interleukin 21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell apoptotic process, T follicular helper cell differentiation, cell development, cell maturation, cellular response to virus, defense response to other organism, germinal center B cell differ...
Does Knockout of Znhit3 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Znhit3
response to virus
Embryonic Fibroblast Cell Line
Gene: Znhit3 (zinc finger, HIT type 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: box C/D snoRNP assembly, maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); MF: metal ion binding, molecular_function, zinc ion binding; CC: cytop...
Does Knockout of Mir6420 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Mir6420
response to virus
Embryonic Fibroblast Cell Line
Gene: Mir6420 (microRNA 6420) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Gtpbp2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Gtpbp2
cell viability
Immortal mouse chromaffin cells
Gene: Gtpbp2 (GTP binding protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nuclear-transcribed mRNA catabolic process, no-go decay, rescue of stalled ribosome, translational elongation; MF: GTP binding, GTPase activity, alpha-aminoacyl-tRNA binding, identical pr...
Does Knockout of Tada2b in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Tada2b
cell cycle progression
breast epithelium
Gene: Tada2b (transcriptional adaptor 2B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin remodeling, regulation of transcription by RNA polymerase II; MF: chromatin binding, transcription coactivator activity; CC: SAGA-type complex, nucleus Pathways: D...
Does Knockout of Nup93 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Nup93
cell proliferation
Colonic Cancer Cell Line
Gene: Nup93 (nucleoporin 93) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA transport, nuclear envelope organization, nuclear pore complex assembly, nucleocytoplasmic transport, poly(A)+ mRNA export from nucleus, positive regulation of SMAD protein signal transducti...
Does Knockout of Chrdl1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Chrdl1
cell proliferation
Embryonic Stem Cell Line
Gene: Chrdl1 (chordin-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: AMPA glutamate receptor clustering, BMP signaling pathway, cell differentiation, cell fate determination, embryonic axis specification, excitatory chemical synaptic transmission, eye development...
Does Knockout of Gins2 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Gins2
cell proliferation
Colonic Cancer Cell Line
Gene: Gins2 (GINS complex subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, double-strand break repair via break-induced replication; CC: CMG complex, GINS complex, chromosome, nucleus Pathways: Cell Cycle, Cell Cycle, Mitotic, DNA Repli...
Does Knockout of Slco1c1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Slco1c1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Slco1c1 (solute carrier organic anion transporter family, member 1c1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bile acid and bile salt transport, lipid transport, monoatomic ion transport, positive regulation of thyroid hormone generation, sodium-independent ...
Does Knockout of Racgap1 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Racgap1
protein/peptide accumulation
Mouse cell
Gene: Racgap1 (Rac GTPase-activating protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rho protein signal transduction, actomyosin contractile ring assembly, cell differentiation, cell division, erythrocyte differentiation, mitotic cytokinesis, mitotic spindle mi...
Does Knockout of Eno4 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Eno4
protein/peptide distribution
myoblast cell line
Gene: Eno4 (enolase 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cilium organization, flagellated sperm motility, glycolytic process; MF: lyase activity, magnesium ion binding, phosphopyruvate hydratase activity, protein binding; CC: phosphopyruvate hydratase comple...
Does Knockout of Atf2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Atf2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Atf2 (activating transcription factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: BMP signaling pathway, DNA damage response, JNK cascade, MAPK cascade, NK T cell differentiation, abducens nucleus development, adipose tissue development, amelogenesis, apoptot...
Does Knockout of Mis18a in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Mis18a
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Mis18a (MIS18 kinetochore protein A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CENP-A containing chromatin assembly, cell division, chromosome segregation, heterochromatin formation, pericentric heterochromatin organization, protein localization to chromosome,...
Does Knockout of Glipr1l2 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Glipr1l2
protein/peptide distribution
myoblast cell line
Gene: Glipr1l2 (GLI pathogenesis-related 1 like 2) Type: protein-coding Summary: No summary available. Gene Ontology: CC: extracellular space, membrane Pathways: UniProt: Q9CQ35 Entrez ID: 67537
Does Knockout of Dmrtc1c2 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Dmrtc1c2
protein/peptide distribution
myoblast cell line
Gene: Dmrtc1c2 (DMRT-like family C1c2) Type: protein-coding Summary: Is expressed in reproductive system. [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: Pathways: UniProt: Q14AJ8, Q9D410, B1AX27 Entrez ID: 668357
Does Knockout of Lin28a in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Lin28a
protein/peptide distribution
myoblast cell line
Gene: Lin28a (lin-28 homolog A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA 3'-end processing, cellular response to glucose stimulus, germ cell development, miRNA catabolic process, miRNA metabolic process, negative regulation of glial cell differentiation, negati...
Does Knockout of Tas2r138 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Tas2r138
cell proliferation
Mouse kidney carcinoma cell
Gene: Tas2r138 (taste receptor, type 2, member 138) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of bitter taste, detection of chemical stimulus involved in sens...
Does Knockout of Pced1a in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Pced1a
cell proliferation
Melanoma Cell Line
Gene: Pced1a (PC-esterase domain containing 1A) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q6P1Z5 Entrez ID: 319513
Does Knockout of Hibch in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Hibch
protein/peptide distribution
myoblast cell line
Gene: Hibch (3-hydroxyisobutyryl-Coenzyme A hydrolase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-valine catabolic process, branched-chain amino acid catabolic process; MF: 3-hydroxyisobutyryl-CoA hydrolase activity, hydrolase activity; CC: mitochondrion P...
Does Knockout of Ccdc62 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Ccdc62
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ccdc62 (coiled-coil domain containing 62) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blastocyst hatching, cellular response to estradiol stimulus, estrogen receptor signaling pathway, positive regulation of transcription by RNA polymerase II, spermatid developm...
Does Knockout of Prdm14 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Prdm14
cell cycle progression
breast epithelium
Gene: Prdm14 (PR domain containing 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell fate specification, cell morphogenesis, embryo implantation, epigenetic regulation of gene expression, fertilization, germ cell development, germ-line stem cell population maintena...
Does Knockout of Cops8 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Cops8
cell cycle progression
breast epithelium
Gene: Cops8 (COP9 signalosome subunit 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: COP9 signalosome assembly, negative regulation of cell population proliferation, protein deneddylation; CC: COP9 signalosome, cytoplasm, cytosol, nucleoplasm, nucleus, perinuclear reg...
Does Knockout of Cebpb in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Cebpb
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cebpb (CCAAT/enhancer binding protein beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, T-helper 1 cell activation, brown fat cell differentiation, cell differentiation, cellular response to amino acid stimulus, cellular response to ...
Does Knockout of Cct4 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Cct4
protein/peptide distribution
myoblast cell line
Gene: Cct4 (chaperonin containing TCP1 subunit 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: binding of sperm to zona pellucida, positive regulation of telomerase RNA localization to Cajal body, positive regulation of telomere maintenance via telomerase, protein fold...
Does Knockout of Pdk2 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Pdk2
response to virus
Embryonic Fibroblast Cell Line
Gene: Pdk2 (pyruvate dehydrogenase kinase, isoenzyme 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to nutrient, cellular response to reactive oxygen species, glucose homeostasis, insulin receptor signaling pathway, intrinsic apoptotic signaling path...
Does Knockout of Dct in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Dct
protein/peptide accumulation
Embryonic Cell Line
Gene: Dct (dopachrome tautomerase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell development, developmental pigmentation, melanin biosynthetic process, melanin biosynthetic process from tyrosine, pigmentation, positive regulation of neuroblast proliferation, respon...
Does Knockout of Fgf3 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Fgf3
protein/peptide accumulation
Embryonic Cell Line
Gene: Fgf3 (fibroblast growth factor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anatomical structure morphogenesis, cell differentiation, fibroblast growth factor receptor signaling pathway, negative regulation of cardiac muscle tissue development, neurogenesis, o...
Does Knockout of Lypd4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Lypd4
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Lypd4 (Ly6/Plaur domain containing 4) Type: protein-coding Summary: Acts upstream of or within binding activity of sperm to zona pellucida and sperm migration through the uterotubal junction. Is active in acrosomal vesicle. Orthologous to human LYPD4 (LY6/PLAUR domain containing 4). [provided by A...
Does Knockout of Vmn1r192 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Vmn1r192
response to virus
Embryonic Fibroblast Cell Line
Gene: Vmn1r192 (vomeronasal 1 receptor 192) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromon...
Does Knockout of Ubl3 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Ubl3
autophagy
Embryonic Fibroblast Cell Line
Gene: Ubl3 (ubiquitin-like 3) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane, plasma membrane Pathways: UniProt: Q9Z2M6 Entrez ID: 24109
Does Knockout of Psma6 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Psma6
cell proliferation
Melanoma Cell Line
Gene: Psma6 (proteasome subunit alpha 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of canonical NF-kappaB signal transduction, proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis involved in protein catabolic process, r...
Does Knockout of Kmt5b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Kmt5b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Kmt5b (lysine methyltransferase 5B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair, chromatin organization, chromatin remodeling, methylation, muscle organ development, positive regulation of double-strand break repair via nonhomologous end joining, posi...
Does Knockout of Brf1 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Brf1
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Brf1 (BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription initiation, positive regulation of transcription by RNA polymerase III, regulation of mRNA stability, transcrip...
Does Knockout of Polr2g in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Polr2g
cell proliferation
Colonic Cancer Cell Line
Gene: Polr2g (polymerase (RNA) II (DNA directed) polypeptide G) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, DNA-templated transcription initiation, nuclear-transcribed mRNA catabolic process, positive regulation of nuclear-transcribed mRNA...
Does Knockout of Tmem215 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Tmem215
cell proliferation
Colonic Cancer Cell Line
Gene: Tmem215 (transmembrane protein 215) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, negative regulation of retinal cell programmed cell death, sprouting angiogenesis Pathways: UniProt: A7E1Z1 Entrez ID: 320500
Does Knockout of Fbxo43 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Fbxo43
cell proliferation
Mouse kidney carcinoma cell
Gene: Fbxo43 (F-box protein 43) Type: protein-coding Summary: No summary available. Gene Ontology: BP: meiotic cell cycle, meiotic nuclear division, negative regulation of cell cycle process, negative regulation of meiotic nuclear division, negative regulation of protein catabolic process, prot...
Does Knockout of Lrfn4 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Lrfn4
response to virus
Embryonic Fibroblast Cell Line
Gene: Lrfn4 (leucine rich repeat and fibronectin type III domain containing 4) Type: protein-coding Summary: Involved in regulation of postsynaptic density assembly; regulation of presynapse assembly; and synaptic membrane adhesion. Located in cell surface. Is active in GABA-ergic synapse and glutamater...
Does Knockout of Prl2c5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Prl2c5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Prl2c5 (prolactin family 2, subfamily c, member 5) Type: protein-coding Summary: Predicted to enable hormone activity and prolactin receptor binding activity. Predicted to be involved in several processes, including female pregnancy; positive regulation of lactation; and positive regulation of rec...
Does Knockout of Lsm6 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Lsm6
cell proliferation
Embryonic Stem Cell Line
Gene: Lsm6 (LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA catabolic process, mRNA processing, mRNA splicing, via spliceosome, maturation of SSU-rRNA, rRNA processing, tRNA processing;...
Does Knockout of Hat1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Hat1
cell proliferation
Embryonic Stem Cell Line
Gene: Hat1 (histone aminotransferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, subtelomeric heterochromatin formation; MF: acyltransferase activity, histone H4 acetyltransferase activity, histone H4K12 acetyltransferase activity, histone a...
Does Knockout of Fbxl22 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Fbxl22
cell cycle progression
breast epithelium
Gene: Fbxl22 (F-box and leucine-rich repeat protein 22) Type: protein-coding Summary: No summary available. Gene Ontology: BP: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, proteasome-mediated ubiquitin-dependent protein catabolic process, protein ubiquitination; CC: ...
Does Knockout of Pa2g4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Pa2g4
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Pa2g4 (proliferation-associated 2G4) Type: protein-coding Summary: Predicted to enable nucleic acid binding activity; transcription corepressor activity; and ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of apoptotic process and positive regulation of c...
Does Knockout of Gadd45g in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Gadd45g
cell proliferation
Mouse kidney carcinoma cell
Gene: Gadd45g (growth arrest and DNA-damage-inducible 45 gamma) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T-helper 1 cell differentiation, apoptotic process, cell differentiation, positive regulation of JNK cascade, positive regulation of MAPK cascade, positive regu...
Does Knockout of Sez6l2 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Sez6l2
response to chemicals
Pancreatic Cancer Cell Line
Gene: Sez6l2 (seizure related 6 homolog like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adult locomotory behavior, cerebellar Purkinje cell layer development, synapse maturation; CC: endoplasmic reticulum, endoplasmic reticulum membrane, membrane, neuronal cell bo...
Does Knockout of Sf3b5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Sf3b5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sf3b5 (splicing factor 3b, subunit 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome, positive regulation of DNA-templated transcription, regulation of DNA repair, regulation of RNA splicing; MF: RNA bin...
Does Knockout of Hspa5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Hspa5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Hspa5 (heat shock protein 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ER overload response, ERAD pathway, IRE1-mediated unfolded protein response, PERK-mediated unfolded protein response, cellular response to glucose starvation, cellular response to interleuk...
Does Knockout of Eml6 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Eml6
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Eml6 (echinoderm microtubule associated protein like 6) Type: protein-coding Summary: No summary available. Gene Ontology: MF: microtubule binding, molecular_function; CC: cytoplasm, cytoskeleton, microtubule Pathways: UniProt: Q5SQM0 Entrez ID: 237711
Does Knockout of Pgd in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Pgd
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pgd (phosphogluconate dehydrogenase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-gluconate metabolic process, NADP+ metabolic process, NADPH regeneration, pentose biosynthetic process, pentose-phosphate shunt, pentose-phosphate shunt, oxidative branch; MF: NAD...
Does Knockout of Fzd5 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Fzd5
cell proliferation
Embryonic Stem Cell Line
Gene: Fzd5 (frizzled class receptor 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, Spemann organizer formation, T cell differentiation in thymus, Wnt signaling pathway, angiogenesis, anterior/posterior axis specification, ...
Does Knockout of Acad11 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Acad11
protein/peptide distribution
myoblast cell line
Gene: Acad11 (acyl-Coenzyme A dehydrogenase family, member 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carboxylic acid catabolic process, fatty acid beta-oxidation, fatty acid beta-oxidation using acyl-CoA dehydrogenase, fatty acid metabolic process, lipid metabol...
Does Knockout of Ptpn20 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Ptpn20
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ptpn20 (protein tyrosine phosphatase, non-receptor type 20) Type: protein-coding Summary: No summary available. Gene Ontology: MF: catalytic activity, hydrolase activity, phosphoprotein phosphatase activity, protein tyrosine phosphatase activity; CC: centriolar satellite, centrosome, cyto...
Does Knockout of Tnrc6a in Pancreatic Cell Line causally result in cell proliferation?
1
2,192
Knockout
Tnrc6a
cell proliferation
Pancreatic Cell Line
Gene: Tnrc6a (trinucleotide repeat containing 6a) Type: protein-coding Summary: This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein is highly similar to a human protein that functions in post-transcriptional gene silencing through the RNA interference (RNAi) a...
Does Knockout of Birc3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Birc3
cell proliferation
Mouse kidney carcinoma cell
Gene: Birc3 (baculoviral IAP repeat-containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cellular response to tumor necrosis factor, necroptotic process, negative regulation of apoptotic process, negative regulation of necroptotic process, nega...
Does Knockout of Phpt1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Phpt1
cell proliferation
Mouse kidney carcinoma cell
Gene: Phpt1 (phosphohistidine phosphatase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, lamellipodium organization, negative regulation of T cell receptor signaling pathway, positive regulation of cell motility; MF: actin filament bin...
Does Knockout of Cd209g in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Cd209g
autophagy
Embryonic Fibroblast Cell Line
Gene: Cd209g (CD209g antigen) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carbohydrate binding, pattern recognition receptor activity Pathways: C-type lectin receptor signaling pathway - Mus musculus (mouse), Measles - Mus musculus (mouse), Phagosome - Mus mu...
Does Knockout of Col23a1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Col23a1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Col23a1 (collagen, type XXIII, alpha 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: extracellular matrix structural constituent conferring tensile strength, heparin binding, identical protein binding; CC: cell surface, collagen trimer, extracellular matrix, extr...
Does Knockout of Rpl30 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Rpl30
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Rpl30 (ribosomal protein L30) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antimicrobial humoral immune response mediated by antimicrobial peptide, cytoplasmic translation, defense response to Gram-negative bacterium, killing of cells of another organism; MF: RNA...
Does Knockout of Vps33a in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Vps33a
cell proliferation
Colonic Cancer Cell Line
Gene: Vps33a (VPS33A CORVET/HOPS core subunit) Type: protein-coding Summary: Acts upstream of or within pigmentation; platelet formation; and regulation of developmental pigmentation. Located in autophagosome and lysosome. Part of CORVET complex. Is expressed in ganglia. Used to study Hermansky-Pudlak s...
Does Knockout of Atf4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Atf4
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Atf4 (activating transcription factor 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GDF15-GFRAL signaling pathway, HRI-mediated signaling, L-asparagine metabolic process, PERK-mediated unfolded protein response, bone mineralization, cellular response to amino a...
Does Knockout of Krr1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Krr1
cell proliferation
Mouse kidney carcinoma cell
Gene: Krr1 (KRR1, small subunit (SSU) processome component, homolog (yeast)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: rRNA processing, ribosomal small subunit biogenesis, ribosome biogenesis; MF: RNA binding, nucleic acid binding; CC: chromosome, intercellular brid...
Does Knockout of Npy4r in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Npy4r
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Npy4r (neuropeptide Y receptor Y4) Type: protein-coding Summary: Enables pancreatic polypeptide receptor activity and peptide YY receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be active in neuron projection and plasma membrane. Orthologous...
Does Knockout of Rbm10 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Rbm10
response to chemicals
Pancreatic Cancer Cell Line
Gene: Rbm10 (RNA binding motif protein 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 3'-UTR-mediated mRNA stabilization, mRNA splicing, via spliceosome, mRNA stabilization, negative regulation of cell growth involved in cardiac muscle cell development, negative regu...
Does Knockout of Socs3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Socs3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Socs3 (suppressor of cytokine signaling 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: branching involved in labyrinthine layer morphogenesis, cell surface receptor signaling pathway via JAK-STAT, cellular response to interleukin-17, cellular response to leukemi...
Does Knockout of Cyp2d26 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Cyp2d26
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cyp2d26 (cytochrome P450, family 2, subfamily d, polypeptide 26) Type: protein-coding Summary: No summary available. Gene Ontology: BP: arachidonate metabolic process, response to xenobiotic stimulus, xenobiotic metabolic process; MF: anandamide 11,12 epoxidase activity, anandamide 14,15 ...
Does Knockout of Tmed9 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Tmed9
cell proliferation
Mouse kidney carcinoma cell
Gene: Tmed9 (transmembrane p24 trafficking protein 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: COPI coating of Golgi vesicle, Golgi organization, endoplasmic reticulum to Golgi vesicle-mediated transport, intracellular protein transport, positive regulation of orga...
Does Knockout of Rpp14 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Rpp14
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Rpp14 (ribonuclease P 14 subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: tRNA 5'-leader removal, tRNA processing; MF: ribonuclease P RNA binding, ribonuclease P activity; CC: endoribonuclease complex, multimeric ribonuclease P complex, nucleolus, nucleus, r...
Does Knockout of Fam131c in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Fam131c
cell cycle progression
breast epithelium
Gene: Fam131c (family with sequence similarity 131, member C) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A2ADB2 Entrez ID: 277743