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string
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string
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Does Knockout of Stxbp2 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Stxbp2
tumorigenicity
Colonic Cancer Cell Line
Gene: Stxbp2 (syntaxin binding protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to type II interferon, exocytosis, intracellular protein transport, leukocyte mediated cytotoxicity, neutrophil degranulation, positive regulation of mast cell degr...
Does Knockout of Barx1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Barx1
cell proliferation
Colonic Cancer Cell Line
Gene: Barx1 (BarH-like homeobox 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, anterior/posterior pattern specification, cell-cell signaling, digestive system development, endothelial cell differentiation, negative regulation of Wnt signaling...
Does Knockout of Pcdhb11 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Pcdhb11
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pcdhb11 (protocadherin beta 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding; CC: membrane, plasma membrane Pathways: ...
Does Knockout of Plekhm2 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Plekhm2
autophagy
Embryonic Fibroblast Cell Line
Gene: Plekhm2 (pleckstrin homology domain containing, family M (with RUN domain) member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, autophagosome-lysosome fusion, late endosome to lysosome transport, lysosome localization, natural killer cell me...
Does Knockout of Skor1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Skor1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Skor1 (SKI family transcriptional corepressor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of BMP signaling pathway, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II; MF: DNA-bind...
Does Knockout of Gng10 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Gng10
cell proliferation
Melanoma Cell Line
Gene: Gng10 (guanine nucleotide binding protein (G protein), gamma 10) Type: protein-coding Summary: Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Is express...
Does Knockout of Sh2d4b in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Sh2d4b
protein/peptide distribution
myoblast cell line
Gene: Sh2d4b (SH2 domain containing 4B) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A6X942 Entrez ID: 328381
Does Knockout of Ddx51 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ddx51
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ddx51 (DEAD box helicase 51) Type: protein-coding Summary: No summary available. Gene Ontology: BP: rRNA processing, ribosome biogenesis; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase activity, hydrolase activity, nucleic acid binding, nucleotide b...
Does Knockout of Taf1a in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Taf1a
cell cycle progression
breast epithelium
Gene: Taf1a (TATA-box binding protein associated factor, RNA polymerase I, A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: transcription by RNA polymerase I; MF: DNA binding, protein binding; CC: RNA polymerase I transcription regulator complex, RNA polymerase transcri...
Does Knockout of Osgep in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Osgep
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Osgep (O-sialoglycoprotein endopeptidase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: tRNA modification, tRNA processing, tRNA threonylcarbamoyladenosine modification; MF: acyltransferase activity, acyltransferase activity, transferring groups other than amino-a...
Does Knockout of Dhfr in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Dhfr
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dhfr (dihydrofolate reductase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon regeneration, dTMP biosynthetic process, dihydrofolate metabolic process, folic acid metabolic process, one-carbon metabolic process, regulation of removal of superoxide radicals, re...
Does Knockout of Atp1a2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Atp1a2
protein/peptide accumulation
Embryonic Cell Line
Gene: Atp1a2 (ATPase, Na+/K+ transporting, alpha 2 polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ATP metabolic process, L-ascorbic acid metabolic process, adult locomotory behavior, amygdala development, behavioral fear response, blood circulation, cell com...
Does Knockout of Rims3 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Rims3
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Rims3 (regulating synaptic membrane exocytosis 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium-ion regulated exocytosis, exocytosis, maintenance of presynaptic active zone structure, neurotransmitter transport, regulation of membrane potential, regulation...
Does Knockout of B3galt6 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
B3galt6
tumorigenicity
Colonic Cancer Cell Line
Gene: B3galt6 (UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chondroitin sulfate proteoglycan biosynthetic process, dermatan sulfate proteoglycan biosynthetic process, glycosaminoglycan biosynthetic process,...
Does Knockout of Pcyt2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Pcyt2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Pcyt2 (phosphate cytidylyltransferase 2, ethanolamine) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid metabolic process, phosphatidylethanolamine biosynthetic process, phospholipid biosynthetic process; MF: catalytic activity, ethanolamine-phosphate cytidylyl...
Does Knockout of Mvb12a in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Mvb12a
protein/peptide accumulation
Embryonic Cell Line
Gene: Mvb12a (multivesicular body subunit 12A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endosome to lysosome transport via multivesicular body sorting pathway, protein transport, receptor catabolic process, regulation of epidermal growth factor receptor signaling p...
Does Knockout of Rpl28 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Rpl28
protein/peptide distribution
myoblast cell line
Gene: Rpl28 (ribosomal protein L28) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: structural constituent of ribosome; CC: cell body, cytoplasm, cytoplasmic ribonucleoprotein...
Does Knockout of Gm4744 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Gm4744
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gm4744 (trypsinogen pseudogene) Type: pseudo Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 194360
Does Knockout of H2-DMa in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
H2-DMa
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: H2-DMa (histocompatibility 2, class II, locus DMa) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processing an...
Does Knockout of Lamc1 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Lamc1
cell proliferation
Melanoma Cell Line
Gene: Lamc1 (laminin, gamma 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ morphogenesis, axon guidance, cell adhesion, cell migration, chromatin organization, extracellular matrix disassembly, gene expression, hair cell differentiation, hair follicle cel...
Does Knockout of Yipf1 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Yipf1
phagocytosis
macrophage
Gene: Yipf1 (Yip1 domain family, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: Golgi apparatus, Golgi medial cisterna, Golgi trans cisterna, endomembrane system, endosome, late endosome membrane, membrane, nucleoplasm, plasma membrane, trans-Golgi network, tra...
Does Knockout of H3f3b in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
H3f3b
protein/peptide distribution
myoblast cell line
Gene: H3f3b (H3.3 histone B) Type: protein-coding Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 ...
Does Knockout of Wiz in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Wiz
protein/peptide accumulation
Embryonic Cell Line
Gene: Wiz (widely-interspaced zinc finger motifs) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of nuclear cell cycle DNA replication, protein stabilization, regulation of transcription by RNA polymerase II; MF: DNA-binding transcription factor activ...
Does Knockout of Eif3d in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Eif3d
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Eif3d (eukaryotic translation initiation factor 3, subunit D) Type: protein-coding Summary: No summary available. Gene Ontology: BP: IRES-dependent viral translational initiation, cap-dependent translational initiation, cytoplasmic translational initiation, formation of cytoplasmic transl...
Does Knockout of Phf12 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Phf12
cell proliferation
Mouse kidney carcinoma cell
Gene: Phf12 (PHD finger protein 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II; MF: metal ion binding, phosphatidylinositol binding, protein binding, transcr...
Does Knockout of Eif5a in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Eif5a
cell proliferation
Melanoma Cell Line
Gene: Eif5a (eukaryotic translation initiation factor 5A) Type: protein-coding Summary: This gene encodes an elongation initiation factor, which participates in protein synthesis. The encoded protein also plays roles in mRNA metabolism, cell proliferation, and cell cycle control. This protein contains a...
Does Knockout of Tubb5 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Tubb5
protein/peptide distribution
myoblast cell line
Gene: Tubb5 (tubulin, beta 5 class I) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule cytoskeleton organization, microtubule-based process, mitotic cell cycle, odontoblast differentiation, regulation of synapse organization, spindle assembly; MF: GTP binding, ...
Does Knockout of Mup14 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Mup14
protein/peptide accumulation
Embryonic Cell Line
Gene: Mup14 (major urinary protein 14) Type: protein-coding Summary: No summary available. Gene Ontology: MF: molecular_function, odorant binding, pheromone binding, small molecule binding; CC: extracellular region, extracellular space Pathways: UniProt: B8JI96, A2CEK7 ...
Does Knockout of P4ha1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
P4ha1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: P4ha1 (procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: collagen fibril organization; MF: L-ascorbic acid binding, dioxygenase activity, identical protein binding, iron io...
Does Knockout of Jagn1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Jagn1
cell proliferation
Embryonic Stem Cell Line
Gene: Jagn1 (jagunal homolog 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to fungus, endoplasmic reticulum organization, granulocyte colony-stimulating factor signaling pathway, immune system process, insulin metabolic process, insulin secretion, ne...
Does Knockout of Chmp6 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Chmp6
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Chmp6 (charged multivesicular body protein 6) Type: protein-coding Summary: Predicted to be involved in several processes, including midbody abscission; regulation of protein metabolic process; and vacuolar transport. Predicted to be located in several cellular components, including bounding membr...
Does Knockout of Cltc in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Cltc
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cltc (clathrin heavy chain) Type: protein-coding Summary: Enables protein kinase binding activity. Predicted to be involved in several processes, including amyloid-beta clearance by transcytosis; endocytosis; and negative regulation of hyaluronan biosynthetic process. Predicted to act upstream of ...
Does Knockout of Chst1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Chst1
cell proliferation
Colonic Cancer Cell Line
Gene: Chst1 (carbohydrate sulfotransferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: N-acetylglucosamine metabolic process, carbohydrate metabolic process, galactose metabolic process, inflammatory response, keratan sulfate proteoglycan biosynthetic process, kera...
Does Knockout of Timm17b in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Timm17b
cell proliferation
Mouse kidney carcinoma cell
Gene: Timm17b (translocase of inner mitochondrial membrane 17b) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein import into mitochondrial matrix, protein transport; MF: protein transmembrane transporter activity; CC: TIM23 mitochondrial import inner membrane trans...
Does Knockout of Tmem175 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Tmem175
cell proliferation
Embryonic Stem Cell Line
Gene: Tmem175 (transmembrane protein 175) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lysosomal lumen pH elevation, monoatomic ion transmembrane transport, monoatomic ion transport, neuron cellular homeostasis, phagosome-lysosome fusion, potassium ion transmembrane tr...
Does Knockout of Ints14 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Ints14
protein/peptide distribution
myoblast cell line
Gene: Ints14 (integrator complex subunit 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II transcription initiation surveillance, snRNA 3'-end processing, snRNA processing; MF: metal ion binding, molecular_function; CC: INTAC complex, integrator comple...
Does Knockout of Cacna1h in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Cacna1h
protein/peptide distribution
myoblast cell line
Gene: Cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit) Type: protein-coding Summary: Voltage-dependent Ca(2+) channels mediate the entry of Ca(2+) ions into excitable cells and are involved in a variety of Ca(2+)-dependent processes, including muscle contraction, hormone or neurotr...
Does Knockout of Txnrd1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Txnrd1
protein/peptide distribution
myoblast cell line
Gene: Txnrd1 (thioredoxin reductase 1) Type: protein-coding Summary: The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocys...
Does Knockout of Rbm18 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Rbm18
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rbm18 (RNA binding motif protein 18) Type: protein-coding Summary: No summary available. Gene Ontology: MF: RNA binding, nucleic acid binding; CC: cytosol, intercellular bridge, nucleoplasm Pathways: UniProt: Q9CR83 Entrez ID: 67889
Does Knockout of Rbm25 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Rbm25
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Rbm25 (RNA binding motif protein 25) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, apoptotic process, mRNA processing, regulation of alternative mRNA splicing, via spliceosome, regulation of apoptotic process; MF: RNA binding, mRNA binding, nucleic a...
Does Knockout of Leo1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Leo1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Leo1 (Leo1, Paf1/RNA polymerase II complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, endodermal cell fate commitment, mRNA 3'-end processing, negative regulation of myeloid cell differentiation, positive regulation of transcri...
Does Knockout of Edem2 in Melanoma Cell Line causally result in cell proliferation?
1
1,157
Knockout
Edem2
cell proliferation
Melanoma Cell Line
Gene: Edem2 (ER degradation enhancer, mannosidase alpha-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, carbohydrate metabolic process, endoplasmic reticulum mannose trimming, endoplasmic reticulum unfolded protein response, positive regulation of re...
Does Knockout of Tcp1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Tcp1
cell proliferation
Embryonic Stem Cell Line
Gene: Tcp1 (t-complex protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: binding of sperm to zona pellucida, positive regulation of establishment of protein localization to telomere, positive regulation of telomerase RNA localization to Cajal body, positive regula...
Does Knockout of Cdt1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Cdt1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cdt1 (chromatin licensing and DNA replication factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, DNA replication checkpoint signaling, DNA replication preinitiation complex assembly, attachment of mitotic spindle microtubules to kinetochore, ...
Does Knockout of Vmn1r196 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Vmn1r196
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Vmn1r196 (vomeronasal 1 receptor 196) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromon...
Does Knockout of Rptor in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Rptor
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Rptor (regulatory associated protein of MTOR, complex 1) Type: protein-coding Summary: This gene encodes a subunit of mammalian target of rapamycin complex 1 (mTORC1), a component of the mTOR signaling pathway, which regulates cell growth in response to nutrient and energy levels. The encoded prot...
Does Knockout of Parn in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Parn
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Parn (poly(A)-specific ribonuclease (deadenylation nuclease)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA catabolic process, box H/ACA sno(s)RNA 3'-end processing, lncRNA processing, mRNA catabolic process, miRNA catabolic process, negative regulation of mac...
Does Knockout of Ceacam2 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Ceacam2
cell proliferation
Embryonic Stem Cell Line
Gene: Ceacam2 (CEA cell adhesion molecule 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bile acid and bile salt transport, cell adhesion, cell-cell adhesion via plasma-membrane adhesion molecules, cellular response to insulin stimulus, energy homeostasis, homophilic ...
Does Knockout of Tnfaip2 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Tnfaip2
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Tnfaip2 (tumor necrosis factor, alpha-induced protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, cell differentiation, exocyst localization, exocytosis; CC: exocyst Pathways: UniProt: Q61333 Entrez ID: 21928
Does Knockout of Wfdc12 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Wfdc12
cell proliferation
Embryonic Stem Cell Line
Gene: Wfdc12 (WAP four-disulfide core domain 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, defense response to bacterium, innate immune response; MF: peptidase inhibitor activity, serine-type endopeptidase inhibitor activity; CC: extr...
Does Knockout of Dlec1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Dlec1
autophagy
Embryonic Fibroblast Cell Line
Gene: Dlec1 (deleted in lung and esophageal cancer 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, defense response to tumor cell, negative regulation of cell population proliferation, spermatogenesis; MF: alpha-tubulin binding, beta-tubulin bindi...
Does Knockout of Stard7 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Stard7
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Stard7 (StAR related lipid transfer domain containing 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: establishment of skin barrier, inflammatory response, mucociliary clearance, myeloid dendritic cell activation, type 2 immune response; MF: lipid binding, molecu...
Does Knockout of Rpl36 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Rpl36
protein/peptide distribution
myoblast cell line
Gene: Rpl36 (ribosomal protein L36) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: structural constituent of ribosome; CC: cytoplasm, cytosol, cytosolic large ribosomal subun...
Does Knockout of Jph4 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Jph4
protein/peptide accumulation
Embryonic Cell Line
Gene: Jph4 (junctophilin 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: learning, neuromuscular process controlling balance, regulation of biological quality, regulation of calcium ion transport, regulation of cytokine production, regulation of store-operated calcium ...
Does Knockout of Sbk1 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Sbk1
response to virus
Embryonic Fibroblast Cell Line
Gene: Sbk1 (SH3-binding kinase 1) Type: protein-coding Summary: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; int...
Does Knockout of Fanca in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Fanca
cell proliferation
Embryonic Stem Cell Line
Gene: Fanca (Fanconi anemia, complementation group A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, female gonad development, interstrand cross-link repair, male gonad development, male meiotic nuclear division, regulation of CD40 signal...
Does Knockout of Msh2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Msh2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Msh2 (mutS homolog 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, B cell mediated immunity, DNA damage response, DNA repair, determination of adult lifespan, developmental process involved in reproduction, double-strand break repair, game...
Does Knockout of Lhx5 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Lhx5
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Lhx5 (LIM homeobox protein 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell proliferation in forebrain, cell-cell signaling, cerebellar Purkinje cell differentiation, cerebellar Purkinje cell-granule cell precursor cell signaling, cerebellum development, fore...
Does Knockout of Psmc3 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Psmc3
cell proliferation
Colonic Cancer Cell Line
Gene: Psmc3 (proteasome (prosome, macropain) 26S subunit, ATPase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blastocyst development, host-mediated perturbation of viral transcription, positive regulation of transcription by RNA polymerase II, proteasome-mediated ub...
Does Knockout of Chchd4 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Chchd4
phagocytosis
macrophage
Gene: Chchd4 (coiled-coil-helix-coiled-coil-helix domain containing 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to leukemia inhibitory factor, cellular response to oxidative stress, establishment of protein localization to mitochondrion, mitochond...
Does Knockout of Ddx28 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Ddx28
cell proliferation
Melanoma Cell Line
Gene: Ddx28 (DEAD box helicase 28) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial large ribosomal subunit assembly, ribosome biogenesis; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase activity, hydrolase activity, nuc...
Does Knockout of Dpysl3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Dpysl3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Dpysl3 (dihydropyrimidinase-like 3) Type: protein-coding Summary: This gene encodes a protein that belongs to the TUC (TOAD-64/Ulip/CRMP) family of proteins. Members of this family are phosphoproteins that function in axonal guidance and neuronal differentiation during development and regeneration...
Does Knockout of Itpripl1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Itpripl1
cell proliferation
Mouse kidney carcinoma cell
Gene: Itpripl1 (inositol 1,4,5-triphosphate receptor interacting protein-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell activation, T cell differentiation, T cell receptor signaling pathway, biological_process, calcium ion import, negative regulation of T ...
Does Knockout of Gprc5b in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Gprc5b
cell proliferation
Melanoma Cell Line
Gene: Gprc5b (G protein-coupled receptor, family C, group 5, member B) Type: protein-coding Summary: Enables protein kinase binding activity and protein kinase inhibitor activity. Involved in several processes, including positive regulation of macromolecule metabolic process; positive regulation of neur...
Does Knockout of Gbp2 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Gbp2
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Gbp2 (guanylate binding protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: AIM2 inflammasome complex assembly, activation of innate immune response, adhesion of symbiont to host, cellular response to interferon-beta, cellular response to lipopolysaccharide, ...
Does Knockout of Rbm17 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Rbm17
cell proliferation
Embryonic Stem Cell Line
Gene: Rbm17 (RNA binding motif protein 17) Type: protein-coding Summary: Predicted to enable RNA binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome. Located in nucleus. Part of protein-containing complex. Is expressed in brain; cerebral cortex; hippocampus; ovary; a...
Does Knockout of Uck1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Uck1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Uck1 (uridine-cytidine kinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CMP biosynthetic process, CTP salvage, UMP salvage; MF: ATP binding, cytidine kinase activity, kinase activity, nucleotide binding, transferase activity, uridine kinase activity ...
Does Knockout of Ipo4 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Ipo4
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ipo4 (importin 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular protein transport, nucleocytoplasmic transport, protein import into nucleus, protein localization to nucleus, protein transport, ribosome biogenesis; MF: nuclear import signal receptor a...
Does Knockout of Rab22a in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Rab22a
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Rab22a (RAB22A, member RAS oncogene family) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endocytosis, endosome organization, intracellular protein transport, protein transport, regulation of vesicle size; MF: G protein activity, GDP binding, GTP binding, GTPase a...
Does Knockout of Cyc1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Cyc1
cell proliferation
Melanoma Cell Line
Gene: Cyc1 (cytochrome c-1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular respiration, mitochondrial electron transport, ubiquinol to cytochrome c, proton transmembrane transport, response to glucagon; MF: electron transfer activity, heme binding, metal ion bin...
Does Knockout of Ptgr1 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Ptgr1
cell proliferation
Regulatory T cell
Gene: Ptgr1 (prostaglandin reductase 1) Type: protein-coding Summary: Predicted to enable 13-lipoxin reductase activity; leukotriene B4 12-hydroxy dehydrogenase activity; and oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor. Predicted to be involved in several proces...
Does Knockout of Inpp4b in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Inpp4b
protein/peptide distribution
myoblast cell line
Gene: Inpp4b (inositol polyphosphate-4-phosphatase, type II) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular calcium ion homeostasis, lipid metabolic process, negative regulation of osteoclast differentiation, phosphatidylinositol dephosphorylation, phosphat...
Does Knockout of Syce1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Syce1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Syce1 (synaptonemal complex central element protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, meiotic cell cycle, synaptonemal complex assembly, synaptonemal complex organization; CC: central element, chromosome, nucleoplasm, nucleus, synapto...
Does Knockout of Prrc2c in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Prrc2c
protein/peptide distribution
myoblast cell line
Gene: Prrc2c (proline-rich coiled-coil 2C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: hematopoietic progenitor cell differentiation, stress granule assembly; CC: cytoplasm, cytoplasmic stress granule, cytosol Pathways: UniProt: Q3TLH4 Entre...
Does Knockout of Ethe1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Ethe1
autophagy
Embryonic Fibroblast Cell Line
Gene: Ethe1 (ethylmalonic encephalopathy 1) Type: protein-coding Summary: Predicted to enable identical protein binding activity; iron ion binding activity; and sulfur dioxygenase activity. Predicted to be involved in glutathione metabolic process and hydrogen sulfide metabolic process. Located in mitoc...
Does Knockout of Taf2 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Taf2
cell proliferation
Colonic Cancer Cell Line
Gene: Taf2 (TATA-box binding protein associated factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G2/M transition of mitotic cell cycle, RNA polymerase II preinitiation complex assembly, mRNA transcription by RNA polymerase II, positive regulation of DNA-templated...
Does Knockout of Scn5a in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Scn5a
response to virus
Embryonic Fibroblast Cell Line
Gene: Scn5a (sodium channel, voltage-gated, type V, alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: AV node cell action potential, AV node cell to bundle of His cell communication, SA node cell action potential, animal organ development, atrial cardiac muscle cell ...
Does Knockout of Eml3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Eml3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Eml3 (echinoderm microtubule associated protein like 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, microtubule cytoskeleton organization, mitotic metaphase chromosome alignment, regulation of mitotic spindle assembly; CC: cytoplasm, cytoskeleton,...
Does Knockout of Tlr2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Tlr2
cell proliferation
Mouse kidney carcinoma cell
Gene: Tlr2 (toll-like receptor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MyD88-dependent toll-like receptor signaling pathway, cell surface pattern recognition receptor signaling pathway, cellular response to bacterial lipopeptide, cellular response to diacyl bac...
Does Knockout of Prr14l in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Prr14l
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Prr14l (proline rich 14-like) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: E9Q7C4, Q6UDR4, Q3UYV6, H3BKZ4, F6RN94 Entrez ID: 215476
Does Knockout of Slc38a5 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Slc38a5
protein/peptide distribution
myoblast cell line
Gene: Slc38a5 (solute carrier family 38, member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-alanine transmembrane transport, L-glutamine import across plasma membrane, L-histidine transmembrane transport, L-serine import across plasma membrane, L-serine transport...
Does Knockout of Spata20 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Spata20
cell proliferation
Embryonic Stem Cell Line
Gene: Spata20 (spermatogenesis associated 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate metabolic process, cell differentiation, spermatogenesis Pathways: UniProt: Q80YT5 Entrez ID: 217116
Does Knockout of Bace1 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Bace1
protein/peptide accumulation
Embryonic Cell Line
Gene: Bace1 (beta-site APP cleaving enzyme 1) Type: protein-coding Summary: This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to genera...
Does Knockout of Nsd2 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Nsd2
cell proliferation
Mouse kidney carcinoma cell
Gene: Nsd2 (nuclear receptor binding SET domain protein 2) Type: protein-coding Summary: Enables chromatin binding activity; histone H3K36 trimethyltransferase activity; and sequence-specific DNA binding activity. Acts upstream of or within several processes, including bone development; cardiac septum m...
Does Knockout of Hinfp in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Hinfp
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Hinfp (histone H4 transcription factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage checkpoint signaling, DNA repair, DNA-templated transcription, G1/S transition of mitotic cell cycle, cell cycle G1/S phase transition, establishment of protein locali...
Does Knockout of Mrpl14 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Mrpl14
response to virus
Embryonic Fibroblast Cell Line
Gene: Mrpl14 (mitochondrial ribosomal protein L14) Type: protein-coding Summary: Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and ...
Does Knockout of Pdcd2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Pdcd2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Pdcd2 (programmed cell death 2) Type: protein-coding Summary: Predicted to enable enzyme binding activity. Predicted to be involved in positive regulation of apoptotic process; positive regulation of hematopoietic stem cell proliferation; and regulation of hematopoietic progenitor cell differentia...
Does Knockout of Hgs in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Hgs
protein/peptide distribution
myoblast cell line
Gene: Hgs (HGF-regulated tyrosine kinase substrate) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endocytic recycling, endosome to lysosome transport, membrane invagination, negative regulation of angiogenesis, negative regulation of platelet-derived growth factor recep...
Does Knockout of Dr1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Dr1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dr1 (down-regulator of transcription 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of cell cycle, ...
Does Knockout of Pcdhga5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Pcdhga5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pcdhga5 (protocadherin gamma subfamily A, 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding, molecular_function; CC: membrane, pl...
Does Knockout of Bnipl in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Bnipl
protein/peptide distribution
Microglial Cell Line
Gene: Bnipl (BCL2/adenovirus E1B 19kD interacting protein like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, negative regulation of cell population proliferation, regulation of growth rate; CC: cytoplasm, cytosol, nucleus Pathways: ...
Does Knockout of Zfp934 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Zfp934
response to chemicals
Pancreatic Cancer Cell Line
Gene: Zfp934 (zinc finger protein 934) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Krtap4-16 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Krtap4-16
response to virus
Microglial Cell Line
Gene: Krtap4-16 (keratin associated protein 4-16) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, cytosol, intermediate filament, keratin filament Pathways: Developmental Biology, Keratinization UniProt: Q91W93 Entrez ID: 4352...
Does Knockout of Reep5 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Reep5
protein/peptide accumulation
Embryonic Cell Line
Gene: Reep5 (receptor accessory protein 5) Type: protein-coding Summary: No summary available. Gene Ontology: CC: endoplasmic reticulum, endoplasmic reticulum membrane, endoplasmic reticulum tubular network, junctional sarcoplasmic reticulum membrane, membrane, sarcoplasmic reticulum, sarcoplas...
Does Knockout of Garem1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Garem1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Garem1 (GRB2 associated regulator of MAPK1 subtype 1) Type: protein-coding Summary: Predicted to enable proline-rich region binding activity. Acts upstream of or within positive regulation of ERK1 and ERK2 cascade. Is expressed in central nervous system; heart; lung; metanephros; and skeletal musc...
Does Knockout of Ssr1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ssr1
cell proliferation
Embryonic Stem Cell Line
Gene: Ssr1 (signal sequence receptor, alpha) Type: protein-coding Summary: No summary available. Gene Ontology: CC: endoplasmic reticulum, endoplasmic reticulum membrane, membrane Pathways: Protein processing in endoplasmic reticulum - Mus musculus (mouse) UniProt: Q9CY50 ...
Does Knockout of Cpq in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Cpq
response to virus
Embryonic Fibroblast Cell Line
Gene: Cpq (carboxypeptidase Q) Type: protein-coding Summary: No summary available. Gene Ontology: BP: peptide catabolic process, proteolysis, thyroid hormone generation, tissue regeneration; MF: carboxypeptidase activity, hydrolase activity, metal ion binding, metallodipeptidase activity, metal...
Does Knockout of Slitrk4 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Slitrk4
cell proliferation
Mouse kidney carcinoma cell
Gene: Slitrk4 (SLIT and NTRK-like family, member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axonogenesis, behavioral fear response, cell population proliferation, long-term synaptic potentiation, memory, positive regulation of synapse assembly, regulation of synap...
Does Knockout of Pik3r1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,174
Knockout
Pik3r1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Pik3r1 (phosphoinositide-3-kinase regulatory subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, T follicular helper cell differentiation, cellular response to UV, cellular response to insulin stimulus, cytokine-mediated signaling path...
Does Knockout of Tbc1d8b in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Tbc1d8b
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Tbc1d8b (TBC1 domain family, member 8B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glomerular filtration, vesicle-mediated transport; MF: GTPase activator activity, calcium ion binding; CC: cytoplasm, cytosol Pathways: Golgi Associated Vesicle Biogenes...