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Does Knockout of Ralgapa2 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Ralgapa2
response to chemicals
Pancreatic Cancer Cell Line
Gene: Ralgapa2 (Ral GTPase activating protein, alpha subunit 2 (catalytic)) Type: protein-coding Summary: Enables GTPase activator activity. Acts upstream of or within several processes, including Ral protein signal transduction; activation of GTPase activity; and regulation of exocyst localization. Pre...
Does Knockout of Snu13 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Snu13
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Snu13 (SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, box C/D snoRNP assembly, mRNA processing, mRNA splicing, via spliceosome, maturation of SSU-rRNA, ribosomal small subunit biogenesis, ribo...
Does Knockout of Id2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Id2
cell proliferation
Colonic Cancer Cell Line
Gene: Id2 (inhibitor of DNA binding 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Peyer's patch development, adipose tissue development, adult locomotory behavior, bundle of His development, cell development, cell differentiation, cell maturation, cell morphogenesis ...
Does Knockout of Lrrc36 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Lrrc36
cell cycle progression
breast epithelium
Gene: Lrrc36 (leucine rich repeat containing 36) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q3V0M2 Entrez ID: 270091
Does Knockout of Ncln in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Ncln
cell cycle progression
breast epithelium
Gene: Ncln (nicalin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: multi-pass transmembrane protein insertion into ER membrane, protein stabilization, regulation of protein complex stability, regulation of protein-containing complex assembly, regulation of signal transd...
Does Knockout of Vwa5b2 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Vwa5b2
protein/peptide accumulation
Mouse cell
Gene: Vwa5b2 (von Willebrand factor A domain containing 5B2) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q3UR50 Entrez ID: 328643
Does Knockout of Igsf9b in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Igsf9b
protein/peptide distribution
myoblast cell line
Gene: Igsf9b (immunoglobulin superfamily, member 9B) Type: protein-coding Summary: Enables kinase binding activity. Involved in synaptic membrane adhesion. Acts upstream of or within homophilic cell adhesion via plasma membrane adhesion molecules and positive regulation of inhibitory postsynaptic potent...
Does Knockout of Mcur1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Mcur1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Mcur1 (mitochondrial calcium uniporter regulator 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium import into the mitochondrion, calcium ion import, calcium ion transmembrane transport, calcium ion transport, cell migration, cell population proliferation, ...
Does Knockout of Dph5 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Dph5
tumorigenicity
Colonic Cancer Cell Line
Gene: Dph5 (diphthamide biosynthesis 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: methylation, protein histidyl modification to diphthamide; MF: diphthine methyl ester synthase activity, diphthine synthase activity, methyltransferase activity, transferase activity; ...
Does Knockout of Phpt1 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Phpt1
cell viability
Immortal mouse chromaffin cells
Gene: Phpt1 (phosphohistidine phosphatase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, lamellipodium organization, negative regulation of T cell receptor signaling pathway, positive regulation of cell motility; MF: actin filament bin...
Does Knockout of Sdr16c5 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Sdr16c5
protein/peptide accumulation
Regulatory T cell
Gene: Sdr16c5 (short chain dehydrogenase/reductase family 16C, member 5) Type: protein-coding Summary: Predicted to enable RNA polymerase II-specific DNA-binding transcription factor binding activity; all-trans-retinol dehydrogenase (NAD+) activity; and transcription corepressor activity. Predicted to b...
Does Knockout of Rab17 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Rab17
cell viability
Immortal mouse chromaffin cells
Gene: Rab17 (RAB17, member RAS oncogene family) Type: protein-coding Summary: Predicted to enable GDP binding activity and GTPase activity. Involved in several processes, including immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor; melanosome transport; and re...
Does Knockout of Fer1l4 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Fer1l4
cell proliferation
Mouse kidney carcinoma cell
Gene: Fer1l4 (fer-1 like family member 4) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, molecular_function; CC: cellular_component, membrane Pathways: UniProt: F6YZT0, Z4YL23, F6UNQ3 Entrez ID: 74562
Does Knockout of Fam53c in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Fam53c
cell proliferation
Mouse kidney carcinoma cell
Gene: Fam53c (family with sequence similarity 53, member C) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8BXQ8 Entrez ID: 66306
Does Knockout of Setd1b in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
1,130
Knockout
Setd1b
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Setd1b (SET domain containing 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, methylation; MF: RNA binding, histone H3K4 methyltransferase activity, histone H3K4 monomethyltransferase activity, histone H3K4 trimethyl...
Does Knockout of Prss22 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Prss22
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Prss22 (serine protease 22) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteolysis; MF: hydrolase activity, peptidase activator activity, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity; CC: extracellular space Pa...
Does Knockout of Ager in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Ager
cell viability
Immortal mouse chromaffin cells
Gene: Ager (advanced glycosylation end product-specific receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, astrocyte activation, astrocyte development, cell adhesion, cell surface receptor signaling pathway via JAK-...
Does Knockout of Nr1h2 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Nr1h2
cell proliferation
Colonic Cancer Cell Line
Gene: Nr1h2 (nuclear receptor subfamily 1, group H, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cholesterol homeostasis, hormone-mediated signaling pathway, intracellular receptor signaling pathway, lipid homeostasis, lipid metabolic pr...
Does Knockout of Stt3b in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Stt3b
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Stt3b (STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, glycoprotein catabolic process, post-translational protein modification, protein N-linked glycosylation, protein N...
Does Knockout of Osgin1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Osgin1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Osgin1 (oxidative stress induced growth inhibitor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, negative regulation of cell growth, signal transduction; MF: growth factor activity, monooxygenase activity, oxidoreductase activity; CC: cellu...
Does Knockout of Phf5a in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Phf5a
protein/peptide accumulation
Mouse cell
Gene: Phf5a (PHD finger protein 5A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome, positive regulation of DNA-templated transcription, stem cell differentiation; MF: DNA binding, RNA binding, metal ion bindin...
Does Knockout of Clip3 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Clip3
protein/peptide distribution
myoblast cell line
Gene: Clip3 (CAP-GLY domain containing linker protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic microtubule organization, fat cell differentiation, membrane biogenesis, negative regulation of microtubule polymerization, peptidyl-L-cysteine S-palmitoyl...
Does Knockout of H2-Eb1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
H2-Eb1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: H2-Eb1 (histocompatibility 2, class II antigen E beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processin...
Does Knockout of Tmed7 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Tmed7
response to virus
Embryonic Fibroblast Cell Line
Gene: Tmed7 (transmembrane p24 trafficking protein 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, endoplasmic reticulum to Golgi vesicle-mediated transport, intracellular protein transport, protein transport; CC: COPI-coated vesicle membrane, COPII...
Does Knockout of Jaml in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Jaml
protein/peptide distribution
myoblast cell line
Gene: Jaml (junction adhesion molecule like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, gamma-delta T cell activation, heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, immune system process, monocyte extravasation, neutrophi...
Does Knockout of Kifc1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,172
Knockout
Kifc1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Kifc1 (kinesin family member C1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, microtubule-based movement, minus-end-directed vesicle transport along microtubule, mitotic metaphase chromosome alignment, mitotic spindle assembly, negative regulation ...
Does Knockout of Smyd4 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Smyd4
protein/peptide distribution
myoblast cell line
Gene: Smyd4 (SET and MYND domain containing 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: heart development, methylation; MF: histone deacetylase binding, metal ion binding, methyltransferase activity, molecular_function, protein-lysine N-methyltransferase activity, ...
Does Knockout of Ajuba in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Ajuba
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ajuba (ajuba LIM protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, cell adhesion, cytoskeleton organization, focal adhesion assembly, glycerophospholipid biosynthetic process, i...
Does Knockout of Polr3c in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Polr3c
protein/peptide distribution
Microglial Cell Line
Gene: Polr3c (polymerase (RNA) III (DNA directed) polypeptide C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, defense response to virus, immune system process, innate immune response, positive regulation of innate immune response, positive ...
Does Knockout of Acot13 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Acot13
cell proliferation
Regulatory T cell
Gene: Acot13 (acyl-CoA thioesterase 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid metabolic process, negative regulation of cold-induced thermogenesis, protein homotetramerization; MF: fatty acyl-CoA hydrolase activity, hydrolase activity; CC: cytoplasm, cytos...
Does Knockout of Eif2s1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Eif2s1
cell proliferation
Embryonic Stem Cell Line
Gene: Eif2s1 (eukaryotic translation initiation factor 2, subunit 1 alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: HRI-mediated signaling, PERK-mediated unfolded protein response, cellular response to UV, cellular response to amino acid starvation, cellular respon...
Does Knockout of Ilf3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Ilf3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ilf3 (interleukin enhancer binding factor 3) Type: protein-coding Summary: The protein encoded by this gene contains two double-stranded RNA binding domains and functions in the post-transcriptional regulation of gene expression. It is a component of an RNA-protein complex that may be involved in ...
Does Knockout of Scnn1a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Scnn1a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Scnn1a (sodium channel, nonvoltage-gated 1 alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to acidic pH, cellular response to aldosterone, cellular response to vasopressin, intracellular sodium ion homeostasis, monoatomic ion transmembrane t...
Does Knockout of Frrs1l in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Frrs1l
protein/peptide distribution
myoblast cell line
Gene: Frrs1l (ferric-chelate reductase 1 like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of AMPA glutamate receptor clustering, regulation of glutamate receptor signaling pathway, regulation of postsynaptic membrane neurotransmitter receptor levels, regul...
Does Knockout of Kntc1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Kntc1
cell proliferation
Colonic Cancer Cell Line
Gene: Kntc1 (kinetochore associated 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, mitotic sister chromatid segregation, mitotic spindle assembly checkpoint signaling, protein localization to kinetochore involved in kinetochore assembly; CC: RZZ complex...
Does Knockout of Elmod3 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Elmod3
protein/peptide distribution
myoblast cell line
Gene: Elmod3 (ELMO/CED-12 domain containing 3) Type: protein-coding Summary: Acts upstream of or within several processes, including cilium assembly; inner ear receptor cell development; and sensory perception of sound. Is active in Golgi apparatus and cilium. Is expressed in cerebral cortex; cerebral c...
Does Knockout of Apol6 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Apol6
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Apol6 (apolipoprotein L 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, lipid transport, lipoprotein metabolic process; MF: lipid binding, molecular_function; CC: cellular_component, extracellular region, membrane Pathways: ...
Does Knockout of Rapgef2 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Rapgef2
cell proliferation
Melanoma Cell Line
Gene: Rapgef2 (Rap guanine nucleotide exchange factor (GEF) 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, Rap protein signal transduction, Ras protein signal transduction, adenylate cyclase-activating adrenergic receptor ...
Does Knockout of Chdh in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Chdh
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Chdh (choline dehydrogenase) Type: protein-coding Summary: No summary available. Gene Ontology: MF: choline dehydrogenase activity, flavin adenine dinucleotide binding, oxidoreductase activity, oxidoreductase activity, acting on CH-OH group of donors; CC: membrane, mitochondrial inner mem...
Does Knockout of Crtam in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Crtam
protein/peptide accumulation
Embryonic Cell Line
Gene: Crtam (cytotoxic and regulatory T cell molecule) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, cell adhesion, cell recognition, detection of stimulus, detection of tumor cell, establishment of T cell polarity, heterophilic cell-cell adhes...
Does Knockout of Col4a5 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Col4a5
cell proliferation
Mouse kidney carcinoma cell
Gene: Col4a5 (collagen, type IV, alpha 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: collagen-activated tyrosine kinase receptor signaling pathway, neuromuscular junction development; MF: extracellular matrix structural constituent, extracellular matrix structural co...
Does Knockout of Gnb1l in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Gnb1l
protein/peptide distribution
myoblast cell line
Gene: Gnb1l (guanine nucleotide binding protein (G protein), beta polypeptide 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage checkpoint signaling, DNA damage response, social behavior; CC: cytoplasm, nucleus Pathways: UniProt: Q9EQ15...
Does Knockout of Mtr in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Mtr
cell proliferation
Colonic Cancer Cell Line
Gene: Mtr (5-methyltetrahydrofolate-homocysteine methyltransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-methionine salvage, amino acid biosynthetic process, axon regeneration, cellular response to nitric oxide, cobalamin metabolic process, homocysteine metab...
Does Knockout of Psma1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Psma1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Psma1 (proteasome subunit alpha 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: immune system process, negative regulation of inflammatory response to antigenic stimulus, proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis involved in p...
Does Knockout of Nuf2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Nuf2
cell viability
Immortal mouse chromaffin cells
Gene: Nuf2 (NUF2, NDC80 kinetochore complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: attachment of mitotic spindle microtubules to kinetochore, attachment of spindle microtubules to kinetochore, cell division, chromosome segregation, kinetochore organiza...
Does Knockout of Golga7b in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Golga7b
cell proliferation
Embryonic Stem Cell Line
Gene: Golga7b (golgin A7B) Type: protein-coding Summary: No summary available. Gene Ontology: MF: enzyme binding, protein binding; CC: Golgi apparatus, Golgi membrane, membrane, palmitoyltransferase complex, plasma membrane Pathways: UniProt: Q9D428 Entrez ID: 71146
Does Knockout of Tapbpl in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,280
Knockout
Tapbpl
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Tapbpl (TAP binding protein-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: immune system process, negative regulation of antigen processing and presentation of peptide antigen via MHC class I, peptide antigen assembly with MHC class I protein complex; MF: MHC...
Does Knockout of Urod in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Urod
protein/peptide accumulation
Regulatory T cell
Gene: Urod (uroporphyrinogen decarboxylase) Type: protein-coding Summary: This gene encodes an enzyme that catalyzes the conversion of uroporphyrinogen-III to coproporphyrinogen-III, an intermediate step in heme biosynthesis. Homozygous knockout mice for this gene exhibit embryonic lethality. [provided ...
Does Knockout of Psma4 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Psma4
protein/peptide distribution
myoblast cell line
Gene: Psma4 (proteasome subunit alpha 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis involved in protein catabolic process, ubiquitin-dependent protein catabolic process; CC: P-body, cytopl...
Does Knockout of Bex4 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Bex4
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Bex4 (brain expressed X-linked 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromosome segregation, negative regulation of protein ubiquitination, negative regulation of tubulin deacetylation, regulation of cell migration, regulation of cell population prolife...
Does Knockout of Fblim1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Fblim1
cell proliferation
Melanoma Cell Line
Gene: Fblim1 (filamin binding LIM protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell-cell adhesion, regulation of cell shape, regulation of integrin activation; MF: filamin binding, metal ion binding, protein binding; CC: anchoring junction, ce...
Does Knockout of Smad9 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Smad9
protein/peptide distribution
myoblast cell line
Gene: Smad9 (SMAD family member 9) Type: protein-coding Summary: This gene encodes a member of a family of proteins that act as downstream effectors of the bone morphogenetic protein (BMP) signaling pathway. The encoded protein is phosphorylated by BMP receptors, which stimulates its binding to SMAD4 an...
Does Knockout of Rdh1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Rdh1
protein/peptide distribution
myoblast cell line
Gene: Rdh1 (retinol dehydrogenase 1 (all trans)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: androgen biosynthetic process, positive regulation of retinoic acid biosynthetic process, retinoic acid metabolic process, retinoid metabolic process, retinol metabolic proces...
Does Knockout of Msn in macrophage causally result in phagocytosis?
1
1,888
Knockout
Msn
phagocytosis
macrophage
Gene: Msn (moesin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell aggregation, T cell migration, T cell proliferation, establishment of endothelial barrier, establishment of epithelial cell apical/basal polarity, gland morphogenesis, immunological synapse formatio...
Does Knockout of Sbpl in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Sbpl
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sbpl (spermine binding protein-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, cell migration; MF: carbohydrate binding, molecular_function; CC: apicolateral plasma membrane, cytoplasm, extracellular region, extracellular space, plasma memb...
Does Knockout of Lad1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Lad1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Lad1 (ladinin) Type: protein-coding Summary: Predicted to enable structural molecule activity. Predicted to be located in actin cytoskeleton. Is expressed in several structures, including ganglia; incisor; sensory organ; submandibular gland primordium; and thymus primordium. Orthologous to human L...
Does Knockout of Glyr1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,271
Knockout
Glyr1
cell proliferation
Mouse kidney carcinoma cell
Gene: Glyr1 (glyoxylate reductase 1 homolog (Arabidopsis)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: transcription elongation-coupled chromatin remodeling, transcription initiation-coupled chromatin remodeling; MF: DNA binding, NAD binding, NADP binding, chromatin b...
Does Knockout of Rasl2-9 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Rasl2-9
cell proliferation
Colonic Cancer Cell Line
Gene: Rasl2-9 (RAS-like, family 2, locus 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GTP metabolic process, glycolytic process, mitotic sister chromatid segregation, nucleocytoplasmic transport, positive regulation of protein import into nucleus, protein export fro...
Does Knockout of Smarcb1 in Lymphoma Cell Line causally result in response to chemicals?
0
1,551
Knockout
Smarcb1
response to chemicals
Lymphoma Cell Line
Gene: Smarcb1 (SWI/SNF related BAF chromatin remodeling complex subunit B1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase I preinitiation complex assembly, blastocyst development, blastocyst hatching, chromatin organization, chromatin remodeling, hepatocy...
Does Knockout of Sncb in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Sncb
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Sncb (synuclein, beta) Type: protein-coding Summary: Predicted to enable metal ion binding activity and tubulin binding activity. Involved in synaptic vesicle endocytosis. Acts upstream of or within several processes, including chemical synaptic transmission; dopamine metabolic process; and negati...
Does Knockout of H2-DMb2 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
H2-DMb2
protein/peptide distribution
myoblast cell line
Gene: H2-DMb2 (histocompatibility 2, class II, locus Mb2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MHC class II protein complex assembly, adaptive immune response, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen...
Does Knockout of Mrps9 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Mrps9
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mrps9 (mitochondrial ribosomal protein S9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: RNA binding, structural constituent of ribosome; CC: intracellular organelle lumen, mitochondrial inner membrane, mitochondrial sma...
Does Knockout of Abraxas1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Abraxas1
cell proliferation
Mouse kidney carcinoma cell
Gene: Abraxas1 (BRCA1 A complex subunit) Type: protein-coding Summary: Predicted to enable microtubule binding activity and polyubiquitin modification-dependent protein binding activity. Predicted to be involved in several processes, including mitotic G2 DNA damage checkpoint signaling; nuclear chromoso...
Does Knockout of Suz12 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Suz12
cell proliferation
Embryonic Stem Cell Line
Gene: Suz12 (SUZ12 polycomb repressive complex 2 subunit) Type: protein-coding Summary: This gene encodes a core component of the polycomb repressive complex 2 (PRC2) that also includes, at least, embryonic ectoderm development protein (EED) and enhancer of zeste homolog 1 or 2 (EZH1 or EZH2). Through t...
Does Knockout of Dis3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Dis3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Dis3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CUT catabolic process, RNA catabolic process, RNA processing, nuclear mRNA surveillance of mRNA 3'-end processing, nuclear-transcribed mRNA catabo...
Does Knockout of Arpc2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Arpc2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Arpc2 (actin related protein 2/3 complex, subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Arp2/3 complex-mediated actin nucleation, actin filament polymerization, cellular response to epidermal growth factor stimulus, cellular response to platelet-derived...
Does Knockout of Adi1 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Adi1
phagocytosis
macrophage
Gene: Adi1 (acireductone dioxygenase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-methionine salvage from methylthioadenosine, amino acid biosynthetic process, methionine biosynthetic process, methionine metabolic process; MF: acireductone dioxygenase (Ni2+-requir...
Does Knockout of Cct4 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Cct4
cell proliferation
Embryonic Stem Cell Line
Gene: Cct4 (chaperonin containing TCP1 subunit 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: binding of sperm to zona pellucida, positive regulation of telomerase RNA localization to Cajal body, positive regulation of telomere maintenance via telomerase, protein fold...
Does Knockout of Ddx11 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Ddx11
cell proliferation
Colonic Cancer Cell Line
Gene: Ddx11 (DEAD/H box helicase 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, cellular response to bleomycin, cellular response to cisplatin, cellular response to hydroxyurea, establishment of sister chromatid cohes...
Does Knockout of Krtap4-6 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Krtap4-6
protein/peptide distribution
myoblast cell line
Gene: Krtap4-6 (keratin associated protein 4-6) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, cytosol, intermediate filament, keratin filament Pathways: Developmental Biology, Keratinization UniProt: Q3V4B7 Entrez ID: 68768
Does Knockout of Pard6g in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Pard6g
protein/peptide accumulation
Mouse cell
Gene: Pard6g (par-6 family cell polarity regulator gamma) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, centrosome cycle, establishment or maintenance of cell polarity, regulation of cellular localization; CC: anchoring junction, apical plasma membrane, b...
Does Knockout of Gabra6 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Gabra6
cell proliferation
Mouse kidney carcinoma cell
Gene: Gabra6 (gamma-aminobutyric acid type A receptor subunit alpha 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chloride transmembrane transport, chloride transport, gamma-aminobutyric acid signaling pathway, inhibitory synapse assembly, monoatomic ion transmembran...
Does Knockout of Lyzl6 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Lyzl6
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Lyzl6 (lysozyme-like 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to bacterium, fertilization, fusion of sperm to egg plasma membrane involved in single fertilization, killing of cells of another organism, single fertilization; MF: catalytic a...
Does Knockout of Tbc1d16 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Tbc1d16
cell proliferation
Embryonic Stem Cell Line
Gene: Tbc1d16 (TBC1 domain family, member 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of receptor recycling; MF: GTPase activator activity; CC: cytosol, early endosome Pathways: Membrane Trafficking, Rab regulation of trafficking, TBC/RABGAPs, ...
Does Knockout of Cd200r1 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Cd200r1
protein/peptide distribution
myoblast cell line
Gene: Cd200r1 (CD200 receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: heterotypic cell-cell adhesion, negative regulation of T cell migration, negative regulation of interleukin-6 production, negative regulation of macrophage migration, negative regulation of n...
Does Knockout of Lmod1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Lmod1
protein/peptide accumulation
Regulatory T cell
Gene: Lmod1 (leiomodin 1 (smooth muscle)) Type: protein-coding Summary: Predicted to enable tropomyosin binding activity. Predicted to be involved in actin cytoskeleton organization; muscle contraction; and positive regulation of actin filament polymerization. Predicted to be located in actin filament; ...
Does Knockout of Gng2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Gng2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Gng2 (guanine nucleotide binding protein (G protein), gamma 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, fibroblast proliferation, signal transduction; MF: G-protein beta-subunit binding, GTPase activity; CC: heter...
Does Knockout of Ddx52 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ddx52
cell proliferation
Embryonic Stem Cell Line
Gene: Ddx52 (DExD box helicase 52) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of SSU-rRNA; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase activity, hydrolase activity, nucleic acid binding, nucleotide binding; CC: nu...
Does Knockout of Iba57 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Iba57
protein/peptide distribution
myoblast cell line
Gene: Iba57 (IBA57 homolog, iron-sulfur cluster assembly) Type: protein-coding Summary: No summary available. Gene Ontology: BP: heme biosynthetic process, iron-sulfur cluster assembly; CC: mitochondrial matrix, mitochondrion Pathways: UniProt: Q8CAK1 Entrez ID: 21679...
Does Knockout of Kctd20 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Kctd20
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Kctd20 (potassium channel tetramerisation domain containing 20) Type: protein-coding Summary: No summary available. Gene Ontology: MF: identical protein binding, protein binding; CC: cytoplasm Pathways: UniProt: Q8CDD8 Entrez ID: 66989
Does Knockout of Mrpl34 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Mrpl34
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mrpl34 (mitochondrial ribosomal protein L34) Type: protein-coding Summary: Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, ...
Does Knockout of Sptb in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Sptb
cell proliferation
Mouse kidney carcinoma cell
Gene: Sptb (spectrin beta, erythrocytic) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, actin filament capping, hemopoiesis, modification of postsynaptic actin cytoskeleton, plasma membrane organization, porphyrin-containing compound bios...
Does Knockout of Rpl13a in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Rpl13a
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Rpl13a (ribosomal protein L13A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to type II interferon, cytoplasmic translation, homeostatic process, lung morphogenesis, macrophage chemotaxis, negative regulation of formation of translation preiniti...
Does Knockout of Plekho2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Plekho2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Plekho2 (pleckstrin homology domain containing, family O member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: macrophage apoptotic process Pathways: Immune System, Innate Immune System, Neutrophil degranulation UniProt: Q8K124 Entrez I...
Does Knockout of Exoc3 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Exoc3
cell proliferation
Melanoma Cell Line
Gene: Exoc3 (exocyst complex component 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: exocyst localization, exocytosis, membrane fission, mitotic cytokinesis, protein transport, vesicle docking involved in exocytosis, vesicle tethering involved in exocytosis; CC: Golg...
Does Knockout of 4931400O07Rik in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
4931400O07Rik
cell proliferation
Melanoma Cell Line
Gene: 4931400O07Rik (RIKEN cDNA 4931400O07 gene) Type: ncRNA Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 70936
Does Knockout of Vmn2r121 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Vmn2r121
cell proliferation
Embryonic Stem Cell Line
Gene: Vmn2r121 (vomeronasal 2, receptor 121) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: A0A...
Does Knockout of Maml1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Maml1
protein/peptide distribution
myoblast cell line
Gene: Maml1 (mastermind like transcriptional coactivator 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, atrioventricular node cell development, myoblast differentiation, positive regulation of muscle cell differentiation, positive regulation o...
Does Knockout of Gabarap in macrophage causally result in phagocytosis?
0
1,888
Knockout
Gabarap
phagocytosis
macrophage
Gene: Gabarap (gamma-aminobutyric acid receptor associated protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, autophagosome assembly, autophagosome maturation, autophagy, cellular response to nitrogen starvation, extrinsic apoptotic signaling path...
Does Knockout of Bcl2l15 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Bcl2l15
protein/peptide distribution
myoblast cell line
Gene: Bcl2l15 (BCLl2-like 15) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, regulation of apoptotic process; CC: cytosol, nucleus Pathways: UniProt: Q08ED0 Entrez ID: 229672
Does Knockout of Cbfa2t3 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Cbfa2t3
protein/peptide distribution
myoblast cell line
Gene: Cbfa2t3 (CBFA2/RUNX1 translocation partner 3) Type: protein-coding Summary: Enables chromatin binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several s...
Does Knockout of Pcnx3 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Pcnx3
cell proliferation
Embryonic Stem Cell Line
Gene: Pcnx3 (pecanex homolog 3) Type: protein-coding Summary: Predicted to be located in membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system. Orthologous to human PCNX3 (pecanex 3). [provided by Alliance of...
Does Knockout of Csnk1a1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Csnk1a1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Csnk1a1 (casein kinase 1, alpha 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, NLRP3 inflammasome complex assembly, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, TORC1 signaling, Wnt signaling pathway, autophagosome...
Does Knockout of Gkap1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Gkap1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Gkap1 (G kinase anchoring protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, cGMP-mediated signaling, positive regulation of insulin receptor signaling pathway, signal ...
Does Knockout of Ephx2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Ephx2
protein/peptide accumulation
Embryonic Cell Line
Gene: Ephx2 (epoxide hydrolase 2, cytoplasmic) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cholesterol homeostasis, dephosphorylation, epoxide metabolic process, linoleic acid metabolic process, lipid metabolic process, phospholipid dephosphorylation, positive regulat...
Does Knockout of Pigl in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Pigl
cell proliferation
Embryonic Stem Cell Line
Gene: Pigl (phosphatidylinositol glycan anchor biosynthesis, class L) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GPI anchor biosynthetic process, lipid metabolic process; MF: N-acetylglucosaminylphosphatidylinositol deacetylase activity, hydrolase activity; CC: endop...
Does Knockout of Dlgap2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Dlgap2
protein/peptide accumulation
Embryonic Cell Line
Gene: Dlgap2 (DLG associated protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: modulation of chemical synaptic transmission, signaling; MF: molecular adaptor activity, protein domain specific binding; CC: dendrite, dendritic spine, glutamatergic synapse, membrane...
Does Knockout of Sp3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Sp3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sp3 (trans-acting transcription factor 3) Type: protein-coding Summary: This gene product belongs to a family of Sp1 related transcription factors, which regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-bindi...
Does Knockout of C1qtnf5 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
C1qtnf5
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: C1qtnf5 (C1q and tumor necrosis factor related protein 5) Type: protein-coding Summary: The protein encoded by this gene is a member of the C1q/tumor necrosis factor superfamily. This family member is a secretory protein that functions in eye development. Mutations in this gene are thought to unde...
Does Knockout of Tbx22 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Tbx22
response to chemicals
Pancreatic Cancer Cell Line
Gene: Tbx22 (T-box 22) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell fate specification, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, positive regulation of DNA-templated transcription, regulation of...