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Does Knockout of Thra in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Thra
protein/peptide distribution
myoblast cell line
Gene: Thra (thyroid hormone receptor alpha) Type: protein-coding Summary: The protein encoded by this gene is one of several nuclear hormone receptors that bind thyroid hormones such as triiodothyronine and thyroxine with high affinity. The encoded protein is a transcription factor that can activate or ...
Does Knockout of Gstm5 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Gstm5
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gstm5 (glutathione S-transferase, mu 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular detoxification of nitrogen compound, glutathione metabolic process, nitrobenzene metabolic process, response to estrogen, xenobiotic catabolic process; MF: enzyme bindin...
Does Knockout of Cul9 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Cul9
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cul9 (cullin 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule cytoskeleton organization, protein ubiquitination, regulation of mitotic nuclear division, ubiquitin-dependent protein catabolic process; MF: ATP binding, metal ion binding, nucleotide bindi...
Does Knockout of Dcun1d5 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Dcun1d5
cell proliferation
Melanoma Cell Line
Gene: Dcun1d5 (defective in cullin neddylation 1 domain containing 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, positive regulation of protein neddylation, protein neddylation, regulation of cell growth, regulation of protein neddylation; MF: cu...
Does Knockout of Hdac5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Hdac5
cell proliferation
Mouse kidney carcinoma cell
Gene: Hdac5 (histone deacetylase 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation, B cell differentiation, cellular response to fluid shear stress, chromatin organization, epigenetic regulation of gene expression, heart development, inflammatory respon...
Does Knockout of Bbox1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Bbox1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Bbox1 (gamma-butyrobetaine hydroxylase 1) Type: protein-coding Summary: Enables gamma-butyrobetaine dioxygenase activity. Involved in carnitine biosynthetic process. Located in mitochondrion. Is active in cytosol. Is expressed in several structures, including alimentary system; genitourinary syste...
Does Knockout of Ferd3l in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ferd3l
cell proliferation
Embryonic Stem Cell Line
Gene: Ferd3l (Fer3 like bHLH transcription factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell development, developmental process, floor plate development, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase ...
Does Knockout of Gtf3c3 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Gtf3c3
cell proliferation
Melanoma Cell Line
Gene: Gtf3c3 (general transcription factor IIIC, polypeptide 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: transcription by RNA polymerase III; CC: fibrillar center, nuclear membrane, nucleoplasm, transcription factor TFIIIC complex Pathways: Gene expression...
Does Knockout of 1700019D03Rik in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
1700019D03Rik
cell proliferation
Mouse kidney carcinoma cell
Gene: 1700019D03Rik (RIKEN cDNA 1700019D03 gene) Type: protein-coding Summary: No summary available. Gene Ontology: MF: molecular_function, protein kinase A regulatory subunit binding; CC: membrane, plasma membrane Pathways: UniProt: Q9CPS8 Entrez ID: 67080
Does Knockout of Cabin1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,286
Knockout
Cabin1
cell proliferation
Mouse kidney carcinoma cell
Gene: Cabin1 (calcineurin binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, negative regulation of apoptotic process, nucleosome assembly, signal transduction; MF: nucleosome binding, protein domain specific binding, protein phosph...
Does Knockout of Hoxb5 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Hoxb5
protein/peptide distribution
myoblast cell line
Gene: Hoxb5 (homeobox B5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterior/posterior pattern specification, embryonic skeletal system development, embryonic skeletal system morphogenesis, endothelial cell differentiation, positive regulation of transcription by RN...
Does Knockout of Dmp1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Dmp1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Dmp1 (dentin matrix protein 1) Type: protein-coding Summary: Enables extracellular matrix binding activity. Acts upstream of or within extracellular matrix organization; positive regulation of cell-substrate adhesion; and regulation of enamel mineralization. Located in cytoplasm; extracellular mat...
Does Knockout of Prkaca in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Prkaca
cell proliferation
Melanoma Cell Line
Gene: Prkaca (protein kinase, cAMP dependent, catalytic, alpha) Type: protein-coding Summary: This gene encodes a member of the serine/threonine protein kinase family. The holoenzyme, protein kinase A (also known as cyclic-AMP dependent protein kinase), mediates cellular response to changes in cyclic-AM...
Does Knockout of Pkn1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Pkn1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pkn1 (protein kinase N1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell apoptotic process, B cell homeostasis, chromatin organization, chromatin remodeling, epithelial cell migration, hyperosmotic response, intracellular signal transduction, negative regulat...
Does Knockout of Rlf in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Rlf
protein/peptide distribution
myoblast cell line
Gene: Rlf (rearranged L-myc fusion sequence) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of heterochromatin formation, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-s...
Does Knockout of Zfp354c in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Zfp354c
protein/peptide distribution
myoblast cell line
Gene: Zfp354c (zinc finger protein 354C) Type: protein-coding Summary: Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of sprou...
Does Knockout of Hs1bp3 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Hs1bp3
response to virus
Embryonic Fibroblast Cell Line
Gene: Hs1bp3 (HCLS1 binding protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell differentiation, cell surface receptor signaling pathway, regulation of apoptotic process; MF: phosphatidylinositol binding, protein binding; CC: endoplasmic reticulum, mitochond...
Does Knockout of Sult1c1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Sult1c1
cell proliferation
Mouse kidney carcinoma cell
Gene: Sult1c1 (sulfotransferase family, cytosolic, 1C, member 1) Type: protein-coding Summary: Enables aryl sulfotransferase activity. Acts upstream of or within sulfur compound metabolic process. Located in cytoplasm. Is expressed in olfactory epithelium. Orthologous to several human genes including SU...
Does Knockout of Nedd9 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Nedd9
protein/peptide accumulation
Regulatory T cell
Gene: Nedd9 (neural precursor cell expressed, developmentally down-regulated gene 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell division, cell migration, cell surface receptor protein tyrosine kinase signaling pathway, cilium disassembly, learning...
Does Knockout of Zfp36l1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Zfp36l1
protein/peptide accumulation
Embryonic Cell Line
Gene: Zfp36l1 (zinc finger protein 36, C3H type-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 3'-UTR-mediated mRNA destabilization, ERK1 and ERK2 cascade, MAPK cascade, T cell differentiation in thymus, apoptotic process, cell population proliferation, cellular ...
Does Knockout of Umps in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Umps
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Umps (uridine monophosphate synthetase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 'de novo' UMP biosynthetic process, 'de novo' pyrimidine nucleobase biosynthetic process, UDP biosynthetic process, UMP biosynthetic process, pyrimidine nucleobase biosynthetic p...
Does Knockout of Pmp22 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Pmp22
cell proliferation
Embryonic Stem Cell Line
Gene: Pmp22 (peripheral myelin protein 22) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Schwann cell development, Schwann cell differentiation, Schwann cell migration, actin cytoskeleton organization, adult locomotory behavior, adult walking behavior, aggresome assembl...
Does Knockout of Ythdf3 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Ythdf3
cell proliferation
Mouse kidney carcinoma cell
Gene: Ythdf3 (YTH N6-methyladenosine RNA binding protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA destabilization, negative regulation of type I interferon-mediated signaling pathway, organelle assembly, positive regulation of translation, positive regulati...
Does Knockout of Rfc3 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Rfc3
cell proliferation
Colonic Cancer Cell Line
Gene: Rfc3 (replication factor C (activator 1) 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair, DNA replication, DNA strand elongation involved in DNA replication, DNA-templated DNA replication, positive regulation of DNA-directed DNA polymerase activity; MF...
Does Knockout of Defb11 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Defb11
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Defb11 (defensin beta 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response, defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, defense response to bacterium, innate immune response in mucosa, response to bacteri...
Does Knockout of Golt1b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Golt1b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Golt1b (golgi transport 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endoplasmic reticulum to Golgi vesicle-mediated transport, protein transport, retrograde transport, endosome to Golgi, vesicle-mediated transport; CC: Golgi apparatus, Golgi membrane, cytopl...
Does Knockout of Cysltr1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Cysltr1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Cysltr1 (cysteinyl leukotriene receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, calcium ion transport, cell surface receptor signaling pathway, cellular response to hypoxia, chemotaxis, endothelium development...
Does Knockout of Mre11a in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Mre11a
tumorigenicity
Colonic Cancer Cell Line
Gene: Mre11a (MRE11A homolog A, double strand break repair nuclease) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA double-strand break processing, DNA repair, DNA strand resection involved in replication fork processing, R-loop processing, cell ...
Does Knockout of Carf in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Carf
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Carf (calcium response factor) Type: protein-coding Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. A...
Does Knockout of Hmgcs2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Hmgcs2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Hmgcs2 (3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acetyl-CoA metabolic process, adipose tissue development, cellular response to amino acid stimulus, cellular response to fatty acid, cellular response to glucoc...
Does Knockout of Lhx8 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Lhx8
protein/peptide accumulation
Mouse cell
Gene: Lhx8 (LIM homeobox protein 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: female gonad development, forebrain neuron development, forebrain neuron differentiation, learning or memory, neuron differentiation, odontogenesis of dentin-containing tooth, regulation o...
Does Knockout of Htr7 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Htr7
cell proliferation
Regulatory T cell
Gene: Htr7 (5-hydroxytryptamine (serotonin) receptor 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, G protein-coupled serotonin r...
Does Knockout of Pdcd2l in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Pdcd2l
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Pdcd2l (programmed cell death 2-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, biological_process Pathways: UniProt: Q8C5N5 Entrez ID: 68079
Does Knockout of Tmem63c in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Tmem63c
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tmem63c (transmembrane protein 63c) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glomerular filtration, monoatomic cation transmembrane transport, monoatomic cation transport, monoatomic ion transmembrane transport, monoatomic ion transport; MF: calcium-activated...
Does Knockout of Etf1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Etf1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Etf1 (eukaryotic translation termination factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translational termination, nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of translational termination, ribosome disassemb...
Does Knockout of Retreg1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Retreg1
protein/peptide distribution
myoblast cell line
Gene: Retreg1 (reticulophagy regulator 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagy, collagen catabolic process, endoplasmic reticulum organization, mitophagy, negative regulation of neuron apoptotic process, reticulophagy, sensory perception of pain, subs...
Does Knockout of Anapc15 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Anapc15
protein/peptide accumulation
Mouse cell
Gene: Anapc15 (anaphase promoting complex C subunit 15) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anaphase-promoting complex-dependent catabolic process, cell division, protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein branched polyubiqui...
Does Knockout of Agpat5 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Agpat5
protein/peptide distribution
myoblast cell line
Gene: Agpat5 (1-acylglycerol-3-phosphate O-acyltransferase 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CDP-diacylglycerol biosynthetic process, acylglycerol metabolic process, hematopoietic progenitor cell differentiation, lipid metabolic process, phosphatidylinosi...
Does Knockout of Paox in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Paox
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Paox (polyamine oxidase (exo-N4-amino)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: polyamine catabolic process, positive regulation of spermidine biosynthetic process, putrescine biosynthetic process, putrescine catabolic process, spermidine catabolic process, ...
Does Knockout of Adam26b in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Adam26b
cell proliferation
Embryonic Stem Cell Line
Gene: Adam26b (a disintegrin and metallopeptidase domain 26B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: male gonad development, proteolysis; MF: metal ion binding, metalloendopeptidase activity, metallopeptidase activity, molecular_function; CC: external side of pla...
Does Knockout of Mnt in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Mnt
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Mnt (max binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular senescence, negative regulation of apoptotic signaling pathway, negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of cel...
Does Knockout of Vkorc1 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Vkorc1
protein/peptide distribution
myoblast cell line
Gene: Vkorc1 (vitamin K epoxide reductase complex, subunit 1) Type: protein-coding Summary: Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blo...
Does Knockout of Cox5b in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Cox5b
response to virus
Embryonic Fibroblast Cell Line
Gene: Cox5b (cytochrome c oxidase subunit 5B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial electron transport, cytochrome c to oxygen, oxidative phosphorylation; CC: membrane, mitochondrial envelope, mitochondrial inner membrane, mitochondrial membrane, m...
Does Knockout of Tbpl2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Tbpl2
cell viability
Immortal mouse chromaffin cells
Gene: Tbpl2 (TATA box binding protein like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription initiation, transcription by RNA polymerase II; MF: DNA binding, RNA polymerase II general transcription initiation factor activity, protein binding; ...
Does Knockout of Apeh in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Apeh
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Apeh (acylpeptide hydrolase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: amyloid-beta metabolic process, proteolysis; MF: hydrolase activity, identical protein binding, omega peptidase activity, peptidase activity, serine-type endopeptidase activity, serine-type...
Does Knockout of Dusp19 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Dusp19
protein/peptide distribution
myoblast cell line
Gene: Dusp19 (dual specificity phosphatase 19) Type: protein-coding Summary: No summary available. Gene Ontology: BP: JNK cascade, negative regulation of JNK cascade, negative regulation of MAPK cascade, positive regulation of JNK cascade, positive regulation of MAPK cascade, regulation of JNK ...
Does Knockout of Ugdh in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Ugdh
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ugdh (UDP-glucose dehydrogenase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: UDP-glucuronate biosynthetic process, chondroitin sulfate proteoglycan biosynthetic process, gastrulation with mouth forming second, glycosaminoglycan biosynthetic process, heparan sulf...
Does Knockout of Ss18 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Ss18
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ss18 (SS18, subunit of BAF chromatin remodeling complex) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell morphogenesis, chromatin remodeling, cytoskeleton organization, ephrin receptor signaling pathway, intracellular signal transduction, microtubule cytoskelet...
Does Knockout of Ppp2r3a in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Ppp2r3a
cell proliferation
Mouse kidney carcinoma cell
Gene: Ppp2r3a (protein phosphatase 2, regulatory subunit B'', alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: eye photoreceptor cell differentiation, negative regulation of canonical Wnt signaling pathway, positive regulation of canonical Wnt signaling pathway, pos...
Does Knockout of Sgip1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Sgip1
cell proliferation
Mouse kidney carcinoma cell
Gene: Sgip1 (SH3-domain GRB2-like (endophilin) interacting protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: clathrin-dependent endocytosis, endocytosis, energy homeostasis, plasma membrane tubulation, positive regulation of eating behavior, positive regulation o...
Does Knockout of Gm9755 in Microglial Cell Line causally result in protein/peptide distribution?
1
1,585
Knockout
Gm9755
protein/peptide distribution
Microglial Cell Line
Gene: Gm9755 (Tu translation elongation factor pseudogene) Type: pseudo Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 100041265
Does Knockout of Il1rn in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Il1rn
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Il1rn (interleukin 1 receptor antagonist) Type: protein-coding Summary: Predicted to enable cytokine receptor binding activity. Acts upstream of or within insulin secretion and lipid metabolic process. Located in extracellular region and vesicle. Is expressed in skin. Human ortholog(s) of this gen...
Does Knockout of Ech1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Ech1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ech1 (enoyl coenzyme A hydratase 1, peroxisomal) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid beta-oxidation, fatty acid metabolic process, lipid metabolic process; MF: catalytic activity, delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity, isomerase...
Does Knockout of Ttbk1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Ttbk1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ttbk1 (tau tubulin kinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: learning or memory, negative regulation of gene expression, positive regulation of astrocyte activation, positive regulation of gene expression, positive regulation of microglial cell activ...
Does Knockout of Fn3krp in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Fn3krp
cell proliferation
Embryonic Stem Cell Line
Gene: Fn3krp (fructosamine 3 kinase related protein) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, kinase activity, nucleotide binding, protein-ribulosamine 3-kinase activity, transferase activity; CC: cellular_component, cytosol Pathways: Gamma ca...
Does Knockout of Lsm10 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Lsm10
cell proliferation
Melanoma Cell Line
Gene: Lsm10 (U7 snRNP-specific Sm-like protein LSM10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA 3'-end processing by stem-loop binding and cleavage, mRNA processing, positive regulation of G1/S transition of mitotic cell cycle; MF: RNA binding, U7...
Does Knockout of Trip12 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Trip12
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Trip12 (thyroid hormone receptor interactor 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, heterochromatin boundary formation, proteasome-mediated ubiquitin-dependent protein catabolic ...
Does Knockout of Mthfd1l in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Mthfd1l
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Mthfd1l (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 10-formyltetrahydrofolate biosynthetic process, carboxylic acid biosynthetic process, embryonic neurocranium morphogenesis, embryonic viscerocr...
Does Knockout of Has1 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Has1
protein/peptide distribution
myoblast cell line
Gene: Has1 (hyaluronan synthase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to platelet-derived growth factor stimulus, estrous cycle, extracellular matrix assembly, glycosaminoglycan biosynthetic process, hyaluronan biosynthetic process, negative...
Does Knockout of Rpl13 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Rpl13
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Rpl13 (ribosomal protein L13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blastocyst development, bone development, cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, structural constituent of ribosome; ...
Does Knockout of Rp9 in Regulatory T cell causally result in protein/peptide accumulation?
1
1,482
Knockout
Rp9
protein/peptide accumulation
Regulatory T cell
Gene: Rp9 (retinitis pigmentosa 9 (human)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, cognition; MF: metal ion binding, protein binding, zinc ion binding; CC: nuclear speck, nucleus, signal recognition particle receptor complex Pathways: Splice...
Does Knockout of Tmem262 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Tmem262
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tmem262 (transmembrane protein 262) Type: protein-coding Summary: No summary available. Gene Ontology: CC: CatSper complex, cell projection, cilium, membrane, motile cilium, plasma membrane Pathways: UniProt: D3Z338 Entrez ID: 433215
Does Knockout of Rhox2d in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Rhox2d
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rhox2d (reproductive homeobox 2D) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, positive regulation of gene expression, positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II; MF: DNA binding...
Does Knockout of Hsf4 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Hsf4
protein/peptide distribution
myoblast cell line
Gene: Hsf4 (heat shock transcription factor 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lens fiber cell differentiation, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, regulation of DNA-templated trans...
Does Knockout of Rnf103 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Rnf103
cell proliferation
Mouse kidney carcinoma cell
Gene: Rnf103 (ring finger protein 103) Type: protein-coding Summary: This gene encodes a member of the RING finger family of E3 ubiquitin-protein ligases. These proteins catalyze the transfer of the ubiquitin protein from a ubiquitin E2 enzyme to a protein substrate. Homozygous knockout mice for this ge...
Does Knockout of Rps6ka6 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Rps6ka6
protein/peptide distribution
Microglial Cell Line
Gene: Rps6ka6 (ribosomal protein S6 kinase polypeptide 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, signal transduction by p53 class mediator, TORC1 signaling, intracellular signal transduction, negative regulation of ERK1 and ERK2 cascade, nega...
Does Knockout of Trmt5 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Trmt5
cell proliferation
Embryonic Stem Cell Line
Gene: Trmt5 (TRM5 tRNA methyltransferase 5) Type: protein-coding Summary: Predicted to enable tRNA methyltransferase activity. Predicted to be involved in mitochondrial tRNA methylation and tRNA N1-guanine methylation. Predicted to be located in nucleus. Predicted to be active in mitochondrial matrix. H...
Does Knockout of Erich2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Erich2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Erich2 (glutamate rich 2) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: E9Q1A6, D3Z5X9, Q9D4B3, F6WLA9 Entrez ID: 66748
Does Knockout of Rwdd4a in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Rwdd4a
cell cycle progression
breast epithelium
Gene: Rwdd4a (RWD domain containing 4A) Type: protein-coding Summary: Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human RWDD4 (RWD domain containing 4). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: Pathways: Uni...
Does Knockout of Naglu in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Naglu
cell cycle progression
breast epithelium
Gene: Naglu (alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, adult behavior, amyloid precursor protein metabolic process, aorta development, aorta morphogenesis, astrocyte activation, astrocyte d...
Does Knockout of Cinp in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Cinp
cell proliferation
Melanoma Cell Line
Gene: Cinp (cyclin dependent kinase 2 interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, biological_process, cell division, ribosomal large subunit biogenesis, ribosome biogenesis; MF: molecular_function,...
Does Knockout of Msl2 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Msl2
cell proliferation
Mouse kidney carcinoma cell
Gene: Msl2 (MSL complex subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, chromatin organization, epigenetic regulation of gene expression, positive regulation of DNA-templated transcription, protein monoubiquitination, protein ubiquitination...
Does Knockout of Naa35 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Naa35
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Naa35 (N(alpha)-acetyltransferase 35, NatC auxiliary subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of apoptotic process, smooth muscle cell proliferation; CC: NatC complex, cytoplasm, cytosol, nucleoplasm, plasma membrane Path...
Does Knockout of Zfand4 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Zfand4
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Zfand4 (zinc finger, AN1-type domain 4) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, molecular_function, zinc ion binding Pathways: UniProt: D3Z3C6 Entrez ID: 67492
Does Knockout of Ivns1abp in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Ivns1abp
protein/peptide accumulation
Regulatory T cell
Gene: Ivns1abp (influenza virus NS1A binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, negative regulation of intrinsic apoptotic signaling pathway, negative regulation of protein ubiquitination, proteasome-mediated ubiquitin-...
Does Knockout of Defa26 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,440
Knockout
Defa26
protein/peptide accumulation
Embryonic Cell Line
Gene: Defa26 (defensin, alpha, 26) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, defense response, defense response to Gram-negative bacterium, defense response to G...
Does Knockout of Ankle2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Ankle2
cell proliferation
Colonic Cancer Cell Line
Gene: Ankle2 (ankyrin repeat and LEM domain containing 2) Type: protein-coding Summary: Predicted to enable protein kinase inhibitor activity and protein phosphatase 2A binding activity. Predicted to be involved in several processes, including mitotic nuclear membrane reassembly; negative regulation of ...
Does Knockout of Vmn1r122 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Vmn1r122
protein/peptide distribution
myoblast cell line
Gene: Vmn1r122 (vomeronasal 1 receptor 122) Type: protein-coding Summary: vomeronasal 1 receptor 122 Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled re...
Does Knockout of Parn in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Parn
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Parn (poly(A)-specific ribonuclease (deadenylation nuclease)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA catabolic process, box H/ACA sno(s)RNA 3'-end processing, lncRNA processing, mRNA catabolic process, miRNA catabolic process, negative regulation of mac...
Does Knockout of Slc25a54 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Slc25a54
response to virus
Embryonic Fibroblast Cell Line
Gene: Slc25a54 (solute carrier family 25, member 54) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ADP transport, ATP transport, transmembrane transport; MF: ATP transmembrane transporter activity, antiporter activity, calcium ion binding, metal ion binding; CC: chromat...
Does Knockout of Mcm6 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Mcm6
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Mcm6 (minichromosome maintenance complex component 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, DNA replication initiation, double-strand break repair via break-induced replication, mitotic DNA replication, premeiotic DNA replication; MF: ATP ...
Does Knockout of Srsf7 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Srsf7
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Srsf7 (serine and arginine-rich splicing factor 7) Type: protein-coding Summary: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM...
Does Knockout of Rad21 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Rad21
protein/peptide accumulation
Embryonic Cell Line
Gene: Rad21 (RAD21 cohesin complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, apoptotic process, cell division, chromatin looping, chromosome segregation, negative regulation of G2/M transition of mitotic cell cycle, negati...
Does Knockout of Gfi1 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Gfi1
cell proliferation
Melanoma Cell Line
Gene: Gfi1 (growth factor independent 1 transcription repressor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, cell fate commitment, cellular response to lipopolysaccharide, double-strand break repair via homologous recombination, inner ear auditory...
Does Knockout of Ndufaf7 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Ndufaf7
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ndufaf7 (NADH:ubiquinone oxidoreductase complex assembly factor 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: methylation, mitochondrial respiratory chain complex I assembly, peptidyl-arginine methylation, to symmetrical-dimethyl arginine; MF: enzyme binding, m...
Does Knockout of Vkorc1l1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Vkorc1l1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Vkorc1l1 (vitamin K epoxide reductase complex, subunit 1-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to oxidative stress, peptidyl-glutamic acid carboxylation, vitamin K metabolic process; MF: oxidoreductase activity, quinone binding, v...
Does Knockout of Taf1b in macrophage causally result in phagocytosis?
0
1,888
Knockout
Taf1b
phagocytosis
macrophage
Gene: Taf1b (TATA-box binding protein associated factor, RNA polymerase I, B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase I preinitiation complex assembly, nucleolar large rRNA transcription by RNA polymerase I, transcription by RNA polymerase I; MF: DN...
Does Knockout of Fgf4 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Fgf4
cell proliferation
Mouse kidney carcinoma cell
Gene: Fgf4 (fibroblast growth factor 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process involved in morphogenesis, cartilage condensation, cell differentiation, cellular response to leukemia inhibitory factor, chondroblast differentiation, cranial suture...
Does Knockout of Cox18 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,286
Knockout
Cox18
cell proliferation
Mouse kidney carcinoma cell
Gene: Cox18 (cytochrome c oxidase assembly protein 18) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial cytochrome c oxidase assembly, protein insertion into membrane, protein insertion into mitochondrial inner membrane from matrix, protein insertion into mit...
Does Knockout of Eda2r in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Eda2r
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Eda2r (ectodysplasin A2 receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cytokine-mediated signaling pathway, intrinsic apoptotic signaling pathway by p53 class mediator, positive regulation of JNK cascade, positive regulation of canon...
Does Knockout of Pnoc in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Pnoc
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Pnoc (prepronociceptin) Type: protein-coding Summary: This gene encodes the precursor for neuropeptides that have been implicated in a wide range of physiological roles such as transmission and sensitivity to pain, learning, memory, anxiety and depression, in the central nervous system. The encode...
Does Knockout of Atp6ap2 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Atp6ap2
protein/peptide distribution
myoblast cell line
Gene: Atp6ap2 (ATPase, H+ transporting, lysosomal accessory protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiotensin maturation, central nervous system maturation, eye pigmentation, head morphogenesis, lysosomal lumen acidification, positive regulation of Wn...
Does Knockout of Mrps28 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Mrps28
protein/peptide distribution
myoblast cell line
Gene: Mrps28 (mitochondrial ribosomal protein S28) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation; CC: mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondrion, ribonucleoprotein complex, ribosome Pathways: Met...
Does Knockout of Faap100 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Faap100
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Faap100 (Fanconi anemia core complex associated protein 100) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, interstrand cross-link repair; MF: DNA binding, molecular_function; CC: Fanconi anaemia nuclear complex, chromatin, cytosol,...
Does Knockout of Gnrhr in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Gnrhr
protein/peptide distribution
myoblast cell line
Gene: Gnrhr (gonadotropin releasing hormone receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, cellular response to gonadotropin-releasing hormone, cellular response to hormone stimulus, negative regulation of cell popu...
Does Knockout of Sbpl in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Sbpl
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sbpl (spermine binding protein-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, cell migration; MF: carbohydrate binding, molecular_function; CC: apicolateral plasma membrane, cytoplasm, extracellular region, extracellular space, plasma memb...
Does Knockout of Mgst3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Mgst3
cell proliferation
Mouse kidney carcinoma cell
Gene: Mgst3 (microsomal glutathione S-transferase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: arachidonate metabolic process, cellular oxidant detoxification, leukotriene biosynthetic process, leukotriene metabolic process, lipid metabolic process, prostanoid metab...
Does Knockout of Ttc8 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
1,130
Knockout
Ttc8
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ttc8 (tetratricopeptide repeat domain 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anatomical structure morphogenesis, axon guidance, camera-type eye photoreceptor cell differentiation, cell projection organization, cilium assembly, establishment of anatomical...
Does Knockout of Rps14 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Rps14
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rps14 (ribosomal protein S14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, erythrocyte differentiation, maturation of SSU-rRNA, negative regulation of transcription by RNA polymerase II, ribosomal small subunit assembly, ribosomal small s...
Does Knockout of Fsd1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Fsd1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Fsd1 (fibronectin type 3 and SPRY domain-containing protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, cytoplasmic microtubule organization, regulation of cell division, regulation of cytokinesis, regulation of mitotic spindle organization; MF: ...