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Does Knockout of Prim1 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Prim1
response to virus
Microglial Cell Line
Gene: Prim1 (DNA primase, p49 subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, DNA replication initiation, DNA replication, synthesis of primer; MF: DNA-directed RNA polymerase activity, magnesium ion binding, metal ion binding, nucleotidyltransfe...
Does Knockout of Cnmd in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Cnmd
cell proliferation
Colonic Cancer Cell Line
Gene: Cnmd (chondromodulin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cartilage development, cell differentiation, endothelial cell morphogenesis, negative regulation of angiogenesis, negative regulation of endothelial cell proliferation, negative regulation of vasc...
Does Knockout of Traf3 in Pancreatic Cell Line causally result in protein/peptide accumulation?
1
2,198
Knockout
Traf3
protein/peptide accumulation
Pancreatic Cell Line
Gene: Traf3 (TNF receptor-associated factor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Toll signaling pathway, antiviral innate immune response, apoptotic process, cell surface receptor signaling pathway, immune system process, innate immune response, mRNA transcr...
Does Knockout of Rpl35 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Rpl35
cell proliferation
Melanoma Cell Line
Gene: Rpl35 (ribosomal protein L35) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), translation, translation at postsynapse, translation at presynapse; MF: m...
Does Knockout of Htatip2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Htatip2
cell proliferation
Embryonic Stem Cell Line
Gene: Htatip2 (HIV-1 Tat interactive protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: alpha-amino acid biosynthetic process, positive regulation of programmed cell death, positive regulation of transcription by RNA polymerase II, regulation of translation; MF: N...
Does Knockout of Nup214 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Nup214
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Nup214 (nucleoporin 214) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA export from nucleus, intracellular protein transport, mRNA export from nucleus, mRNA transport, nucleocytoplasmic transport, protein export from nucleus, protein import into nucleus, protei...
Does Knockout of Il9r in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Il9r
protein/peptide distribution
myoblast cell line
Gene: Il9r (interleukin 9 receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, B cell proliferation, immunoglobulin mediated immune response, interleukin-9-mediated signaling pathway, positive regulation of cell growth; MF: cytokine receptor a...
Does Knockout of Slc4a4 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Slc4a4
cell proliferation
Melanoma Cell Line
Gene: Slc4a4 (solute carrier family 4 (anion exchanger), member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bicarbonate transport, establishment of localization in cell, inorganic anion transport, monoatomic anion transmembrane transport, monoatomic anion transport...
Does Knockout of Hnrnpdl in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Hnrnpdl
cell proliferation
Colonic Cancer Cell Line
Gene: Hnrnpdl (heterogeneous nuclear ribonucleoprotein D-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA metabolic process, regulation of gene expression; MF: DNA binding, RNA binding, double-stranded DNA binding, nucleic acid binding, poly(A) binding, poly(G) ...
Does Knockout of Ulk2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Ulk2
cell proliferation
Mouse kidney carcinoma cell
Gene: Ulk2 (unc-51 like kinase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, autophagy, axon extension, axon guidance, axonogenesis, collateral sprouting, intracellular protein localization, mitophagy, negative regulation of collateral sprouti...
Does Knockout of Nrl in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Nrl
cell proliferation
Embryonic Stem Cell Line
Gene: Nrl (neural retina leucine zipper gene) Type: protein-coding Summary: This gene encodes a member of the basic leucine zipper domain family of transcription factors. The encoded protein is preferentially expressed in the retina and is necessary for rod photoreceptor development. Alternative splicin...
Does Knockout of Bcs1l in macrophage causally result in phagocytosis?
0
1,888
Knockout
Bcs1l
phagocytosis
macrophage
Gene: Bcs1l (BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone) Type: protein-coding Summary: The protein encoded by this gene is a chaperone protein that is involved in the assembly of complex III (CIII), one of the five protein complexes of the mitochondrial respiratory chain, and is ne...
Does Knockout of Cpt1c in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Cpt1c
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cpt1c (carnitine palmitoyltransferase 1c) Type: protein-coding Summary: Enables palmitoyl-(protein) hydrolase activity. Involved in regulation of postsynaptic membrane neurotransmitter receptor levels. Located in axon; dendrite; and endoplasmic reticulum. Part of AMPA glutamate receptor complex. I...
Does Knockout of Gpr88 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Gpr88
protein/peptide distribution
myoblast cell line
Gene: Gpr88 (G-protein coupled receptor 88) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, adrenergic receptor signaling pathway, cellular response to...
Does Knockout of Lrfn4 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Lrfn4
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Lrfn4 (leucine rich repeat and fibronectin type III domain containing 4) Type: protein-coding Summary: Involved in regulation of postsynaptic density assembly; regulation of presynapse assembly; and synaptic membrane adhesion. Located in cell surface. Is active in GABA-ergic synapse and glutamater...
Does Knockout of Hnrnpl in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Hnrnpl
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Hnrnpl (heterogeneous nuclear ribonucleoprotein L) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to amino acid starvation, mRNA processing, negative regulation of DNA-templated transcription, negative regulation of mRNA splicing, via spliceosome,...
Does Knockout of Rp1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Rp1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Rp1 (retinitis pigmentosa 1 (human)) Type: protein-coding Summary: This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two doublecortin domains, which bind microtubules and regulate microtubule polymerization. The encoded protein is a photoreceptor micr...
Does Knockout of Dzip1l in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Dzip1l
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Dzip1l (DAZ interacting protein 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ciliary transition zone assembly, cilium assembly, floor plate development, neural tube patterning, protein localization to cilium, regulation of protein localization, smoothened...
Does Knockout of Gusb in Microglial Cell Line causally result in protein/peptide distribution?
1
1,585
Knockout
Gusb
protein/peptide distribution
Microglial Cell Line
Gene: Gusb (glucuronidase, beta) Type: protein-coding Summary: Enables beta-glucuronidase activity. Involved in chondroitin sulfate proteoglycan catabolic process; heparan sulfate proteoglycan catabolic process; and hyaluronan catabolic process. Acts upstream of or within carbohydrate metabolic process....
Does Knockout of Mcidas in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Mcidas
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mcidas (multiciliate differentiation and DNA synthesis associated cell cycle protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, centriole assembly, cilium assembly, motile cilium assembly, multi-ciliated epithelial cell differenti...
Does Knockout of Mus81 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Mus81
response to chemicals
Pancreatic Cancer Cell Line
Gene: Mus81 (MUS81 structure-specific endonuclease subunit) Type: protein-coding Summary: Predicted to enable 3'-flap endonuclease activity. Predicted to contribute to crossover junction DNA endonuclease activity. Predicted to be involved in DNA metabolic process; mitotic intra-S DNA damage checkpoint s...
Does Knockout of Poc1a in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Poc1a
response to chemicals
Pancreatic Cancer Cell Line
Gene: Poc1a (POC1 centriolar protein A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bone development, cell projection organization, cilium assembly, growth plate cartilage chondrocyte development, mitotic spindle organization, non-motile cilium assembly, positive regu...
Does Knockout of Mfn2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Mfn2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mfn2 (mitofusin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, apoptotic process, autophagy, blastocyst formation, camera-type eye morphogenesis, intracellular distribution of mitochondria, mitochondrial calcium ion homeostasis, mitochondria...
Does Knockout of Smim14 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Smim14
cell proliferation
Embryonic Stem Cell Line
Gene: Smim14 (small integral membrane protein 14) Type: protein-coding Summary: No summary available. Gene Ontology: CC: endoplasmic reticulum, endoplasmic reticulum membrane, membrane Pathways: UniProt: Q91VT8 Entrez ID: 68552
Does Knockout of Itga2b in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Itga2b
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Itga2b (integrin alpha 2b) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, cell adhesion, cell-cell adhesion, cell-matrix adhesion, integrin-mediated signaling pathway, positive regulation of leukocyte migration; MF: extracellular matrix binding, fibri...
Does Knockout of Cabin1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Cabin1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cabin1 (calcineurin binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, negative regulation of apoptotic process, nucleosome assembly, signal transduction; MF: nucleosome binding, protein domain specific binding, protein phosph...
Does Knockout of Psmc4 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Psmc4
cell viability
Immortal mouse chromaffin cells
Gene: Psmc4 (proteasome (prosome, macropain) 26S subunit, ATPase, 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blastocyst development, proteasome-mediated ubiquitin-dependent protein catabolic process; MF: ATP binding, ATP hydrolysis activity, nucleotide binding, pr...
Does Knockout of Rfx2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Rfx2
cell proliferation
Colonic Cancer Cell Line
Gene: Rfx2 (regulatory factor X, 2 (influences HLA class II expression)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acrosome assembly, cell differentiation, cell projection organization, cellular response to leukemia inhibitory factor, cilium assembly, positive regul...
Does Knockout of Traf3 in Malignant Peripheral Nerve Sheath Tumor (MPNST) cancer cell causally result in tumorigenicity?
1
2,184
Knockout
Traf3
tumorigenicity
Malignant Peripheral Nerve Sheath Tumor (MPNST) cancer cell
Gene: Traf3 (TNF receptor-associated factor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Toll signaling pathway, antiviral innate immune response, apoptotic process, cell surface receptor signaling pathway, immune system process, innate immune response, mRNA transcr...
Does Knockout of Rgs19 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Rgs19
protein/peptide distribution
myoblast cell line
Gene: Rgs19 (regulator of G-protein signaling 19) Type: protein-coding Summary: Predicted to enable G-protein alpha-subunit binding activity. Predicted to be involved in negative regulation of signal transduction. Predicted to be located in brush border and clathrin-coated vesicle. Is expressed in embry...
Does Knockout of Lrfn2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Lrfn2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Lrfn2 (leucine rich repeat and fibronectin type III domain containing 2) Type: protein-coding Summary: Involved in modulation of chemical synaptic transmission and regulation of postsynapse organization. Located in cell surface. Is active in Schaffer collateral - CA1 synapse; postsynapse; and pres...
Does Knockout of Gm2a in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Gm2a
cell proliferation
Embryonic Stem Cell Line
Gene: Gm2a (GM2 ganglioside activator protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ganglioside catabolic process, ganglioside metabolic process, glycosphingolipid catabolic process, learning or memory, lipid metabolic process, lipid storage, lipid transport, n...
Does Knockout of Zfp456 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Zfp456
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfp456 (zinc finger protein 456) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Rpl12 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Rpl12
cell proliferation
Mouse kidney carcinoma cell
Gene: Rpl12 (ribosomal protein L12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, large ribosomal subunit rRNA binding, structural constituent of ribosome; CC: ...
Does Knockout of Zfp949 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Zfp949
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Zfp949 (zinc finger protein 949) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Cd300ld4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Cd300ld4
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cd300ld4 (CD300 molecule like family member D4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, immune response-activating signaling pathway, immune system process; MF: molecular_function, transmembrane signaling receptor activity; CC: cellular_c...
Does Knockout of Tinf2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Tinf2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tinf2 (Terf1 (TRF1)-interacting nuclear factor 2) Type: protein-coding Summary: Enables telomeric DNA binding activity. Acts upstream of or within negative regulation of telomere maintenance. Located in chromosome, telomeric region. Is expressed in several structures, including genitourinary syste...
Does Knockout of Tsga13 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Tsga13
cell cycle progression
breast epithelium
Gene: Tsga13 (testis specific gene A13) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9DA17 Entrez ID: 116732
Does Knockout of Rhox2h in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Rhox2h
cell proliferation
Mouse kidney carcinoma cell
Gene: Rhox2h (reproductive homeobox 2H) Type: protein-coding Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Ge...
Does Knockout of Rcc2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Rcc2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Rcc2 (regulator of chromosome condensation 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: activation of GTPase activity, cell division, chromosome passenger complex localization to kinetochore, establishment of protein localization, focal adhesion assembly, inte...
Does Knockout of Dlgap3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Dlgap3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Dlgap3 (DLG associated protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: modification of postsynaptic structure, modulation of chemical synaptic transmission, protein-containing complex assembly, signaling; MF: PDZ domain binding, amyloid-beta binding, mole...
Does Knockout of Dmap1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Dmap1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dmap1 (DNA methyltransferase 1-associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair, chromatin organization, chromatin remodeling, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase ...
Does Knockout of Pam16 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Pam16
protein/peptide distribution
myoblast cell line
Gene: Pam16 (presequence translocase-asssociated motor 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA biosynthetic process, negative regulation of apoptotic signaling pathway, ossification, protein import into mitochondrial matrix, protein transport; CC: PAM comp...
Does Knockout of Ankrd33 in Microglial Cell Line causally result in response to virus?
0
1,438
Knockout
Ankrd33
response to virus
Microglial Cell Line
Gene: Ankrd33 (ankyrin repeat domain 33) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, skeletal muscle cell differentiation; CC: cytoplasm, cytosol, nucleus Pathways: UniProt: Q8BXP5 E...
Does Knockout of Cad in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Cad
cell proliferation
Colonic Cancer Cell Line
Gene: Cad (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 'de novo' UMP biosynthetic process, 'de novo' pyrimidine nucleobase biosynthetic process, UDP biosynthetic process, UTP biosyntheti...
Does Knockout of Orc3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Orc3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Orc3 (origin recognition complex, subunit 3) Type: protein-coding Summary: Predicted to enable DNA replication origin binding activity. Acts upstream of or within glial cell proliferation and neural precursor cell proliferation. Predicted to be located in chromatin and nuclear body. Predicted to b...
Does Knockout of Gnai2 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Gnai2
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Gnai2 (G protein subunit alpha i2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled acetylcholine receptor signaling pathway, G protein-coupled adenosine receptor signaling pathway, G protein-coupled receptor signaling pathway, adenylate cyclase-act...
Does Knockout of Serpinb8 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Serpinb8
protein/peptide distribution
myoblast cell line
Gene: Serpinb8 (serine (or cysteine) peptidase inhibitor, clade B, member 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: epithelial cell-cell adhesion; MF: peptidase inhibitor activity, serine-type endopeptidase inhibitor activity; CC: cytoplasm, cytosol, extracellula...
Does Knockout of Dpysl5 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Dpysl5
response to virus
Embryonic Fibroblast Cell Line
Gene: Dpysl5 (dihydropyrimidinase-like 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon guidance, negative regulation of dendrite morphogenesis, neuron differentiation, pyrimidine nucleobase catabolic process; MF: dihydropyrimidinase activity, hydrolase activity, h...
Does Knockout of Ankmy2 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Ankmy2
cell proliferation
Melanoma Cell Line
Gene: Ankmy2 (ankyrin repeat and MYND domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: enzyme binding, metal ion binding, zinc ion binding; CC: cell projection, cellular_component, cilium Pathways: UniProt: Q3TPE9 Entrez ID: ...
Does Knockout of Cox11 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Cox11
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cox11 (cytochrome c oxidase assembly protein 11, copper chaperone) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ATP biosynthetic process, intracellular monoatomic cation homeostasis; MF: copper ion binding, protein binding; CC: membrane, mitochondrial inner membr...
Does Knockout of Sema4g in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Sema4g
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Sema4g (sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon guidance, cell differentiation, negative chemotaxis, nervous system development, neural cre...
Does Knockout of Rundc3a in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Rundc3a
cell proliferation
Colonic Cancer Cell Line
Gene: Rundc3a (RUN domain containing 3A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of cGMP-mediated signaling Pathways: UniProt: O08576 Entrez ID: 51799
Does Knockout of Rnf44 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Rnf44
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Rnf44 (ring finger protein 44) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, ubiquitin protein ligase activity, zinc ion binding Pathways: UniProt: Q3UHJ8 Entrez ID: 105239
Does Knockout of Ccdc169 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Ccdc169
cell proliferation
Mouse kidney carcinoma cell
Gene: Ccdc169 (coiled-coil domain containing 169) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8BXX9 Entrez ID: 320604
Does Knockout of Uqcr10 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Uqcr10
cell cycle progression
breast epithelium
Gene: Uqcr10 (ubiquinol-cytochrome c reductase, complex III subunit X) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular respiration, mitochondrial electron transport, ubiquinol to cytochrome c; CC: membrane, mitochondrial inner membrane, mitochondrion, respiratory...
Does Knockout of Serpinb12 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Serpinb12
protein/peptide distribution
myoblast cell line
Gene: Serpinb12 (serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12) Type: protein-coding Summary: No summary available. Gene Ontology: MF: peptidase inhibitor activity, serine-type endopeptidase inhibitor activity; CC: cornified envelope, cytoplasm, extracellular space ...
Does Knockout of Adra1a in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Adra1a
protein/peptide accumulation
Embryonic Cell Line
Gene: Adra1a (adrenergic receptor, alpha 1a) Type: protein-coding Summary: This gene encodes one of several multipass transmembrane proteins that function as G protein-coupled receptors. The encoded protein binds to epinephrine and norepinephrine to mediate signaling in cells of the cardiac, nervous, an...
Does Knockout of Cdc20 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Cdc20
cell proliferation
Colonic Cancer Cell Line
Gene: Cdc20 (cell division cycle 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G2/M transition of mitotic cell cycle, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, anaphase-promoting complex-dependent catabolic process, cell differentiatio...
Does Knockout of Pick1 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Pick1
cell proliferation
Melanoma Cell Line
Gene: Pick1 (protein interacting with C kinase 1) Type: protein-coding Summary: Enables protein kinase C binding activity and signaling receptor binding activity. Involved in receptor clustering. Acts upstream of or within protein targeting. Located in several cellular components, including Golgi appara...
Does Knockout of Zfp131 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Zfp131
cell proliferation
Colonic Cancer Cell Line
Gene: Zfp131 (zinc finger protein 131) Type: protein-coding Summary: This gene encodes a member of the BTB/POZ family of transcription factors. This protein has been found to act as a transcriptional activator and may regulate estrogen receptor signaling. Alternative splicing results in multiple transcr...
Does Knockout of Tex19.1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Tex19.1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tex19.1 (testis expressed gene 19.1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cell proliferation involved in embryonic placenta development, homologous chromosome pairing at meiosis, in utero embryonic development, male gonad development...
Does Knockout of Crybb2 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Crybb2
protein/peptide distribution
myoblast cell line
Gene: Crybb2 (crystallin, beta B2) Type: protein-coding Summary: This gene is a member of the beta-crystallin family. Beta crystallins, along with alpha and gamma crystallins, are the major proteins found in the eye lens. These proteins maintain the refractive index of the lens whilst also maintaining i...
Does Knockout of Pex26 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Pex26
cell proliferation
Regulatory T cell
Gene: Pex26 (peroxisomal biogenesis factor 26) Type: protein-coding Summary: This gene is a member of the peroxin-26 family. The encoded protein is probably required for protein import into peroxisomes. It may anchor Pex1 and Pex6 to peroxisome membranes. Defects in a similar gene in human are the cause...
Does Knockout of Gstt1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Gstt1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gstt1 (glutathione S-transferase, theta 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA modification, cellular oxidant detoxification, dichloromethane metabolic process, glutathione metabolic process, response to salicylic acid, response to selenium ion, resp...
Does Knockout of Adprhl1 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Adprhl1
cell cycle progression
breast epithelium
Gene: Adprhl1 (ADP-ribosylhydrolase like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cardiac chamber ballooning, cardiac myofibril assembly, protein de-ADP-ribosylation; MF: ADP-ribosylarginine hydrolase activity, magnesium ion binding; CC: cytoplasm, sarcomere ...
Does Knockout of Dnaaf5 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Dnaaf5
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Dnaaf5 (dynein, axonemal assembly factor 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, cilium movement, inner dynein arm assembly, outer dynein arm assembly; MF: dynein intermediate chain binding; CC: cytoplasm, cytosol, dynein axo...
Does Knockout of Cbln3 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Cbln3
phagocytosis
macrophage
Gene: Cbln3 (cerebellin 3 precursor protein) Type: protein-coding Summary: No summary available. Gene Ontology: CC: Golgi apparatus, endoplasmic reticulum, extracellular region, extracellular space, parallel fiber to Purkinje cell synapse, synapse, synaptic cleft Pathways: Un...
Does Knockout of Gng12 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Gng12
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gng12 (guanine nucleotide binding protein (G protein), gamma 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G-protein beta-subunit binding, PDZ domain binding, phosphate ion binding; CC: act...
Does Knockout of Hcfc2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,278
Knockout
Hcfc2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Hcfc2 (host cell factor C2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antiviral innate immune response, chromatin remodeling, immune response involved in response to exogenous dsRNA, negative regulation of transcription by RNA polymerase II, positive regulatio...
Does Knockout of Qpctl in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,172
Knockout
Qpctl
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Qpctl (glutaminyl-peptide cyclotransferase-like) Type: protein-coding Summary: No summary available. Gene Ontology: MF: acyltransferase activity, glutaminyl-peptide cyclotransferase activity, metal ion binding, transferase activity, zinc ion binding; CC: Golgi apparatus, Golgi membrane, m...
Does Knockout of Mrpl3 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Mrpl3
cell proliferation
Embryonic Stem Cell Line
Gene: Mrpl3 (mitochondrial ribosomal protein L3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, ribonuc...
Does Knockout of Rpp21 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Rpp21
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rpp21 (ribonuclease P 21 subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA processing, response to xenobiotic stimulus, tRNA 5'-leader removal, tRNA processing; MF: metal ion binding, ribonuclease P RNA binding, ribonuclease P activity; CC: endoribonuclea...
Does Knockout of Lrrc63 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Lrrc63
cell proliferation
Embryonic Stem Cell Line
Gene: Lrrc63 (leucine rich repeat containing 63) Type: protein-coding Summary: Predicted to be involved in intracellular signal transduction. Orthologous to human LRRC63 (leucine rich repeat containing 63). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: Pathways: ...
Does Knockout of Tln1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Tln1
cell proliferation
Colonic Cancer Cell Line
Gene: Tln1 (talin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, cell adhesion, cell junction assembly, cell-cell adhesion, cell-substrate junction assembly, cortical actin cytoskeleton organization, cortical microtubule organization, ...
Does Knockout of Fcho1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Fcho1
cell proliferation
Colonic Cancer Cell Line
Gene: Fcho1 (FCH domain only 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell receptor signaling pathway, clathrin coat assembly, clathrin-dependent endocytosis, endocytosis, positive regulation of T cell activation; MF: AP-2 adaptor complex binding, protein bind...
Does Knockout of Rnase6 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Rnase6
cell proliferation
Mouse kidney carcinoma cell
Gene: Rnase6 (ribonuclease, RNase A family, 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, defense response to Gram-negative bacterium, defense response to Gram-po...
Does Knockout of Dnajc18 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Dnajc18
cell proliferation
Colonic Cancer Cell Line
Gene: Dnajc18 (DnaJ heat shock protein family (Hsp40) member C18) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to misfolded protein, protein folding; CC: endoplasmic reticulum, endoplasmic reticulum membrane, membrane Pathways: UniP...
Does Knockout of Stt3a in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Stt3a
cell proliferation
Mouse kidney carcinoma cell
Gene: Stt3a (STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: post-translational protein modification, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein ...
Does Knockout of Tekt2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Tekt2
cell proliferation
Mouse kidney carcinoma cell
Gene: Tekt2 (tektin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, cilium assembly, cilium movement involved in cell motility, flagellated sperm motility, inner dynein arm assembly; CC: axonemal A tubule inner sheath, axonemal microtubule...
Does Knockout of Liph in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Liph
protein/peptide distribution
myoblast cell line
Gene: Liph (lipase, member H) Type: protein-coding Summary: Predicted to enable heparin binding activity and phospholipase activity. Predicted to be involved in lipid catabolic process. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in extracellular space. Is...
Does Knockout of Acacb in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Acacb
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Acacb (acetyl-Coenzyme A carboxylase beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-glucose import, acetyl-CoA metabolic process, acyl-CoA metabolic process, energy homeostasis, fatty acid biosynthetic process, fatty acid metabolic process, fatty acid oxida...
Does Knockout of Trip13 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Trip13
cell proliferation
Melanoma Cell Line
Gene: Trip13 (thyroid hormone receptor interactor 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, double-strand break repair, female meiosis I, male meiosis I, meiotic cell cycle, meiotic recombination checkpoint signaling, mitotic spindle assemb...
Does Knockout of Nphs1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Nphs1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Nphs1 (nephrosis 1, nephrin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: JNK cascade, MAPK cascade, cell adhesion, cell-cell adhesion, gene expression, glomerular basement membrane development, muscle organ development, myoblast fusion, podocyte development, pos...
Does Knockout of 1700012B07Rik in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
1700012B07Rik
cell proliferation
Embryonic Stem Cell Line
Gene: 1700012B07Rik (RIKEN cDNA 1700012B07 gene) Type: protein-coding Summary: RIKEN cDNA 1700012B07 gene Gene Ontology: MF: molecular_function, protein binding Pathways: UniProt: Q9DAE9, Q3V0S8, A2AGP8 Entrez ID: 69324
Does Knockout of Ilk in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Ilk
cell proliferation
Mouse kidney carcinoma cell
Gene: Ilk (integrin linked kinase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Schwann cell development, anatomical structure morphogenesis, branching involved in ureteric bud morphogenesis, caveola assembly, cell differentiation, cell morphogenesis, cell projection o...
Does Knockout of Ephb1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Ephb1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ephb1 (Eph receptor B1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, axon guidance, camera-type eye morphogenesis, cell activation, cell adhesion, cell chemotaxis, cell migration, cell surface receptor protein tyrosine kinase signaling pathway, cell...
Does Knockout of Tomm40l in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Tomm40l
autophagy
Embryonic Fibroblast Cell Line
Gene: Tomm40l (translocase of outer mitochondrial membrane 40-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transport, protein import into mitochondrial matrix, protein transport, transmembrane transport; MF: mitochondrion targeting sequence binding...
Does Knockout of Sly in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Sly
response to virus
Embryonic Fibroblast Cell Line
Gene: Sly (Sycp3 like Y-linked) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A0A087WRK1, Q810R0, A0A9L6KDV5, A0A087WNQ6 Entrez ID: 382301
Does Knockout of 4930451I11Rik in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
4930451I11Rik
protein/peptide distribution
myoblast cell line
Gene: 4930451I11Rik (RIKEN cDNA 4930451I11 gene) Type: protein-coding Summary: Involved in fusion of sperm to egg plasma membrane involved in single fertilization. Predicted to be located in extracellular region and plasma membrane. Orthologous to human C16orf92 (chromosome 16 open reading frame 92). [p...
Does Knockout of Grwd1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Grwd1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Grwd1 (glutamate-rich WD repeat containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, nucleosome assembly, nucleosome disassembly, ribosome biogenesis; MF: DNA replication origin binding, chromatin binding, histone binding; CC: chromosome, c...
Does Knockout of Inppl1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Inppl1
protein/peptide accumulation
Embryonic Cell Line
Gene: Inppl1 (inositol polyphosphate phosphatase-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERK1 and ERK2 cascade, actin filament organization, apoptotic process, cell adhesion, endochondral ossification, endocytosis, establishment of mitotic spindle orientat...
Does Knockout of Pex3 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Pex3
protein/peptide distribution
myoblast cell line
Gene: Pex3 (peroxisomal biogenesis factor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: peroxisome membrane biogenesis, peroxisome organization, protein import into peroxisome membrane; MF: lipid binding, protein-macromolecule adaptor activity; CC: cytosol, endoplasm...
Does Knockout of Metap1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Metap1
cell proliferation
Embryonic Stem Cell Line
Gene: Metap1 (methionyl aminopeptidase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein maturation, proteolysis; MF: aminopeptidase activity, hydrolase activity, initiator methionyl aminopeptidase activity, metal ion binding, metalloaminopeptidase activity, pept...
Does Knockout of Colec10 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Colec10
protein/peptide accumulation
Mouse cell
Gene: Colec10 (collectin sub-family member 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: complement activation, lectin pathway, cranial skeletal system development, defense response, embryo development ending in birth or egg hatching, heterophilic cell-cell adhesion...
Does Knockout of Garem1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Garem1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Garem1 (GRB2 associated regulator of MAPK1 subtype 1) Type: protein-coding Summary: Predicted to enable proline-rich region binding activity. Acts upstream of or within positive regulation of ERK1 and ERK2 cascade. Is expressed in central nervous system; heart; lung; metanephros; and skeletal musc...
Does Knockout of Derl1 in Microglial Cell Line causally result in response to virus?
1
2,429
Knockout
Derl1
response to virus
Microglial Cell Line
Gene: Derl1 (Der1-like domain family, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, cellular response to misfolded protein, cellular response to stress, cellular response to unfolded protein, endoplasmic reticulum unfolded protein response, posit...
Does Knockout of Commd9 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Commd9
cell cycle progression
breast epithelium
Gene: Commd9 (COMM domain containing 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cholesterol homeostasis, monoatomic ion transport, sodium ion transport; CC: Golgi apparatus, cytoplasmic vesicle, cytosol, nucleoplasm, nucleus Pathways: Immune System, Innat...
Does Knockout of Cyp2c40 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Cyp2c40
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cyp2c40 (cytochrome P450, family 2, subfamily c, polypeptide 40) Type: protein-coding Summary: No summary available. Gene Ontology: BP: arachidonate metabolic process, epoxygenase P450 pathway, estrogen metabolic process, icosanoid biosynthetic process, lipid hydroxylation, lipid metaboli...
Does Knockout of Znhit2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Znhit2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Znhit2 (zinc finger, HIT domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, zinc ion binding Pathways: UniProt: Q9QY66 Entrez ID: 29805