prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of Hcfc1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 82 | Knockout | Hcfc1 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Hcfc1 (host cell factor C1)
Type: protein-coding
Summary: This gene encodes a transcription cofactor that regulates the progression of cell cycle and maintain the ability of embryonic stem cells to self-renew. The encoded protein is a large precursor that undergoes site-specific proteolytic cleava... |
Does Knockout of Pgam1 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 1,264 | Knockout | Pgam1 | cell proliferation | Colonic Cancer Cell Line | Gene: Pgam1 (phosphoglycerate mutase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: canonical glycolysis, gluconeogenesis, glyceraldehyde-3-phosphate biosynthetic process, glycolytic process; MF: bisphosphoglycerate mutase activity, catalytic activity, hydrolase activ... |
Does Knockout of Cyb5b in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,267 | Knockout | Cyb5b | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Cyb5b (cytochrome b5 type B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: nitric oxide biosynthetic process; MF: enzyme activator activity, heme binding, metal ion binding, nitrite reductase (NO-forming) activity; CC: intracellular membrane-bounded organelle, mem... |
Does Knockout of Engase in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,679 | Knockout | Engase | protein/peptide distribution | myoblast cell line | Gene: Engase (endo-beta-N-acetylglucosaminidase)
Type: protein-coding
Summary: Predicted to enable mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity. Acts upstream of or within protein deglycosylation. Predicted to be located in cytosol. Orthologous to human ENGASE (endo-beta-N-acetylgluc... |
Does Knockout of Pno1 in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 2,477 | Knockout | Pno1 | cell proliferation | Embryonic Stem Cell Line | Gene: Pno1 (partner of NOB1 homolog)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, ribosomal small subunit biogenesis; MF: RNA binding, molecular_function, nucleic acid binding; CC: nucleolus, nucleoplasm, nucleus, small-subunit processome
P... |
Does Knockout of Naa20 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,267 | Knockout | Naa20 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: N-terminal peptidyl-aspartic acid acetylation, N-terminal peptidyl-glutamic acid acetylation, N-terminal peptidyl-glutamine acetylation, N-terminal protein ... |
Does Knockout of Polg in Melanoma Cell Line causally result in cell proliferation? | 1 | 1,270 | Knockout | Polg | cell proliferation | Melanoma Cell Line | Gene: Polg (polymerase (DNA directed), gamma)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA biosynthetic process, DNA metabolic process, DNA replication, DNA replication proofreading, DNA-templated DNA replication, base-excision repair, determination of adult lifesp... |
Does Knockout of Pcdhgc5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 81 | Knockout | Pcdhgc5 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Pcdhgc5 (protocadherin gamma subfamily C, 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules, negative regulation of neuron apoptotic process, synapse organization; MF: calcium ion bindin... |
Does Knockout of Slc2a6 in Mouse cell causally result in protein/peptide accumulation? | 0 | 1,047 | Knockout | Slc2a6 | protein/peptide accumulation | Mouse cell | Gene: Slc2a6 (solute carrier family 2 (facilitated glucose transporter), member 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: D-glucose transmembrane transport, regulation of glycolytic process, transmembrane transport; MF: D-glucose transmembrane transporter activit... |
Does Knockout of Hmgcl in Breast Adenocarcinoma Cell Line causally result in tumorigenicity? | 0 | 2,171 | Knockout | Hmgcl | tumorigenicity | Breast Adenocarcinoma Cell Line | Gene: Hmgcl (3-hydroxy-3-methylglutaryl-Coenzyme A lyase)
Type: protein-coding
Summary: Predicted to enable several functions, including anion binding activity; hydroxymethylglutaryl-CoA lyase activity; and metal ion binding activity. Acts upstream of or within mitochondrion organization. Located in mit... |
Does Knockout of Mms22l in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,267 | Knockout | Mms22l | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Mms22l (MMS22-like, DNA repair protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, chromatin organization, double-strand break repair via homologous recombination, protein localization to chromatin, replication fork processing; ... |
Does Knockout of Ap3m1 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,684 | Knockout | Ap3m1 | protein/peptide distribution | myoblast cell line | Gene: Ap3m1 (adaptor-related protein complex 3, mu 1 subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: anterograde axonal transport, anterograde synaptic vesicle transport, clathrin-coated vesicle cargo loading, AP-3-mediated, endocytosis, intracellular protein tra... |
Does Knockout of Pex13 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 161 | Knockout | Pex13 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Pex13 (peroxisomal biogenesis factor 13)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to reactive oxygen species, cerebral cortex cell migration, fatty acid alpha-oxidation, locomotory behavior, microtubule-based peroxisome localization, neuron ... |
Does Knockout of Atm in Lymphoma Cell Line causally result in response to chemicals? | 1 | 1,540 | Knockout | Atm | response to chemicals | Lymphoma Cell Line | Gene: Atm (ataxia telangiectasia mutated)
Type: protein-coding
Summary: Enables histone H2AXS139 kinase activity. Involved in several processes, including cellular response to retinoic acid; negative regulation of TORC1 signaling; and regulation of macromolecule biosynthetic process. Acts upstream of or... |
Does Knockout of Arhgef33 in Pancreatic Cancer Cell Line causally result in response to chemicals? | 0 | 2,359 | Knockout | Arhgef33 | response to chemicals | Pancreatic Cancer Cell Line | Gene: Arhgef33 (Rho guanine nucleotide exchange factor 33)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: guanyl-nucleotide exchange factor activity, molecular_function
Pathways: Cell death signalling via NRAGE, NRIF and NADE, Death Receptor Signaling, G alpha (... |
Does Knockout of Stn1 in breast epithelium causally result in cell cycle progression? | 0 | 1,470 | Knockout | Stn1 | cell cycle progression | breast epithelium | Gene: Stn1 (STN1, CST complex subunit)
Type: protein-coding
Summary: Enables single-stranded DNA binding activity and telomeric DNA binding activity. Involved in positive regulation of DNA replication. Located in chromosome, telomeric region and nucleus. Part of CST complex. Human ortholog(s) of this ge... |
Does Knockout of Ppif in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 161 | Knockout | Ppif | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Ppif (peptidylprolyl isomerase F (cyclophilin F))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic mitochondrial changes, apoptotic process, cellular response to arsenic-containing substance, cellular response to calcium ion, cellular response to hydrogen p... |
Does Knockout of Itgb1bp2 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 1,275 | Knockout | Itgb1bp2 | cell proliferation | Colonic Cancer Cell Line | Gene: Itgb1bp2 (integrin beta 1 binding protein 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: SH3 domain binding, calcium ion binding, integrin binding, metal ion binding, protein binding, zinc ion binding; CC: Z disc
Pathways:
UniProt: Q9R000
... |
Does Knockout of Sav1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 81 | Knockout | Sav1 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Sav1 (salvador family WW domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, hair follicle development, hippo signaling, intestinal epithelial cell differentiation, keratinocyte differentiation, lung epithelial cell differentiatio... |
Does Knockout of Dgkk in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation? | 0 | 1,522 | Knockout | Dgkk | protein/peptide accumulation | Embryonic Fibroblast Cell Line | Gene: Dgkk (diacylglycerol kinase kappa)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: diacylglycerol metabolic process, glycerolipid metabolic process, intracellular signal transduction, lipid metabolic process, phosphatidic acid biosynthetic process, phospholipase C-a... |
Does Knockout of Vipr2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 82 | Knockout | Vipr2 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Vipr2 (vasoactive intestinal peptide receptor 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled r... |
Does Knockout of Yeats2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,267 | Knockout | Yeats2 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Yeats2 (YEATS domain containing 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin remodeling, negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of cell cycle, regulation of cell division, regu... |
Does Knockout of Gck in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,290 | Knockout | Gck | cell proliferation | Mouse kidney carcinoma cell | Gene: Gck (glucokinase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: NADP+ metabolic process, calcium ion import, carbohydrate metabolic process, carbohydrate phosphorylation, cellular response to glucose starvation, cellular response to insulin stimulus, cellular resp... |
Does Knockout of Rictor in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,682 | Knockout | Rictor | protein/peptide distribution | myoblast cell line | Gene: Rictor (RPTOR independent companion of MTOR, complex 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: TOR signaling, TORC2 signaling, actin cytoskeleton organization, cGAS/STING signaling pathway, cellular response to nutrient levels, cytoskeleton organization, em... |
Does Knockout of Siah1a in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,286 | Knockout | Siah1a | cell proliferation | Mouse kidney carcinoma cell | Gene: Siah1a (siah E3 ubiquitin protein ligase 1A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, canonical Wnt signaling pathway, cell differentiation, male meiosis I, neuron apoptotic process, positive regulation of apoptotic process, positive regula... |
Does Knockout of Slit2 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,271 | Knockout | Slit2 | cell proliferation | Mouse kidney carcinoma cell | Gene: Slit2 (slit guidance ligand 2)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the Slit family of secreted glycoproteins, which function as ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal... |
Does Knockout of Mpi in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Mpi | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Mpi (mannose phosphate isomerase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: GDP-D-mannose biosynthetic process from fructose-6-phosphate, GDP-mannose biosynthetic process, carbohydrate metabolic process, glycolytic process from mannose through fructose-6-phosp... |
Does Knockout of Dtx2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Dtx2 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Dtx2 (deltex 2, E3 ubiquitin ligase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Notch signaling pathway, protein ubiquitination; MF: metal ion binding, protein binding, transferase activity, ubiquitin protein ligase activity, zinc ion binding; CC: cytoplasm, nu... |
Does Knockout of Gpr139 in breast epithelium causally result in cell cycle progression? | 0 | 1,470 | Knockout | Gpr139 | cell cycle progression | breast epithelium | Gene: Gpr139 (G protein-coupled receptor 139)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, neuropeptide signaling pathway, phospholipase C-activating G protein-coupled receptor signaling pathway, signal transduction; MF: G ... |
Does Knockout of Uqcrc2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 83 | Knockout | Uqcrc2 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Uqcrc2 (ubiquinol cytochrome c reductase core protein 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular respiration, mitochondrial electron transport, ubiquinol to cytochrome c, proteolysis, response to xenobiotic stimulus; MF: metal ion binding, metalloen... |
Does Knockout of Kcnj13 in Embryonic Fibroblast Cell Line causally result in response to virus? | 1 | 1,133 | Knockout | Kcnj13 | response to virus | Embryonic Fibroblast Cell Line | Gene: Kcnj13 (potassium inwardly-rectifying channel, subfamily J, member 13)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion import across plasma membrane, potassium ion transmembrane transpor... |
Does Knockout of Tm4sf5 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 578 | Knockout | Tm4sf5 | cell proliferation | Embryonic Stem Cell Line | Gene: Tm4sf5 (transmembrane 4 superfamily member 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: regulation of G1/S transition of mitotic cell cycle; MF: arginine binding; CC: lysosomal membrane, membrane, plasma membrane
Pathways:
UniProt: Q9D8G1, Q... |
Does Knockout of Cd320 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 83 | Knockout | Cd320 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Cd320 (CD320 antigen)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell costimulation, cobalamin transport, positive regulation of B cell proliferation, regulation of vitamin metabolic process, signal transduction, vesicle-mediated transport; MF: calcium ion bi... |
Does Knockout of Rnaseh2c in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 1,265 | Knockout | Rnaseh2c | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Rnaseh2c (ribonuclease H2, subunit C)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA catabolic process, mismatch repair; CC: nucleus, ribonuclease H2 complex
Pathways: DNA replication - Mus musculus (mouse)
UniProt: Q9CQ18
Entrez ID: 6... |
Does Knockout of Tsc22d2 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,681 | Knockout | Tsc22d2 | protein/peptide distribution | myoblast cell line | Gene: Tsc22d2 (TSC22 domain family, member 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of cell cycle, regulation of transcription by RNA polymerase II, response to osmotic stress
Pathways:
UniProt: E9Q7M2
Entrez ID: 72... |
Does Knockout of Plekha2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 83 | Knockout | Plekha2 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Plekha2 (pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of cell-matrix adhesion; MF: PDZ domain binding, fibronectin binding, laminin binding, lipid bi... |
Does Knockout of Ldlrap1 in Regulatory T cell causally result in cell proliferation? | 0 | 2,127 | Knockout | Ldlrap1 | cell proliferation | Regulatory T cell | Gene: Ldlrap1 (low density lipoprotein receptor adaptor protein 1)
Type: protein-coding
Summary: Enables amyloid-beta binding activity. Acts upstream of or within cholesterol homeostasis. Located in early endosome and neurofilament. Is expressed in extraembryonic endoderm; nose; and skin. Used to study ... |
Does Knockout of Ly6c1 in Pancreatic Cancer Cell Line causally result in response to chemicals? | 0 | 2,359 | Knockout | Ly6c1 | response to chemicals | Pancreatic Cancer Cell Line | Gene: Ly6c1 (lymphocyte antigen 6 family member C1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: acetylcholine receptor binding, acetylcholine receptor inhibitor activity; CC: cell surface, external side of plasma membrane, membrane, plasma membrane, side of membrane, ... |
Does Knockout of Dhcr24 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,267 | Knockout | Dhcr24 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Dhcr24 (24-dehydrocholesterol reductase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Ras protein signal transduction, amyloid precursor protein catabolic process, cholesterol biosynthetic process, cholesterol biosynthetic process via desmosterol, cholesterol bio... |
Does Knockout of Rsph14 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 81 | Knockout | Rsph14 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Rsph14 (radial spoke head homolog 14 (Chlamydomonas))
Type: protein-coding
Summary: Predicted to be involved in epithelial cilium movement involved in extracellular fluid movement; flagellated sperm motility; and mating. Part of radial spoke. Is expressed in lung epithelium and nasal cavity respir... |
Does Knockout of Il27ra in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,262 | Knockout | Il27ra | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Il27ra (interleukin 27 receptor, alpha)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell surface receptor signaling pathway, defense response to Gram-positive bacterium, interleukin-27-mediated signaling pathway, negative regulation of T cell extravasation, nega... |
Does Knockout of Ndufa1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,262 | Knockout | Ndufa1 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Ndufa1 (NADH:ubiquinone oxidoreductase subunit A1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: aerobic respiration, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrion, respira... |
Does Knockout of Cped1 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,684 | Knockout | Cped1 | protein/peptide distribution | myoblast cell line | Gene: Cped1 (cadherin-like and PC-esterase domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: endoplasmic reticulum
Pathways:
UniProt: A0A2Z4MSG2, B2RX70, D3YUQ2, E9Q7L8, S4R2A1
Entrez ID: 214642 |
Does Knockout of Pcdhga12 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,278 | Knockout | Pcdhga12 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Pcdhga12 (protocadherin gamma subfamily A, 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calci... |
Does Knockout of Urod in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,679 | Knockout | Urod | protein/peptide distribution | myoblast cell line | Gene: Urod (uroporphyrinogen decarboxylase)
Type: protein-coding
Summary: This gene encodes an enzyme that catalyzes the conversion of uroporphyrinogen-III to coproporphyrinogen-III, an intermediate step in heme biosynthesis. Homozygous knockout mice for this gene exhibit embryonic lethality. [provided ... |
Does Knockout of Fasn in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,262 | Knockout | Fasn | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Fasn (fatty acid synthase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: acetyl-CoA metabolic process, cellular response to interleukin-4, epithelial cell development, establishment of endothelial intestinal barrier, ether lipid biosynthetic process, fatty acid bi... |
Does Knockout of Rnf214 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 161 | Knockout | Rnf214 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Rnf214 (ring finger protein 214)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: metal ion binding, ubiquitin-protein transferase activity, zinc ion binding
Pathways:
UniProt: Q8BFU3
Entrez ID: 235315 |
Does Knockout of Ubald2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 161 | Knockout | Ubald2 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Ubald2 (UBA-like domain containing 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q8BQH4
Entrez ID: 319370 |
Does Knockout of Vmn1r235 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 161 | Knockout | Vmn1r235 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Vmn1r235 (vomeronasal 1 receptor 235)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromon... |
Does Knockout of Syp in Breast Adenocarcinoma Cell Line causally result in tumorigenicity? | 0 | 2,171 | Knockout | Syp | tumorigenicity | Breast Adenocarcinoma Cell Line | Gene: Syp (synaptophysin)
Type: protein-coding
Summary: Enables SH2 domain binding activity and identical protein binding activity. Involved in regulation of long-term neuronal synaptic plasticity; regulation of short-term neuronal synaptic plasticity; and regulation of synaptic vesicle priming. Located... |
Does Knockout of Nrros in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 83 | Knockout | Nrros | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Nrros (negative regulator of reactive oxygen species)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ERAD pathway, immune response, inflammatory response, innate immune response, microglia development, sequestering of TGFbeta in extracellular matrix, superoxide met... |
Does Knockout of Evl in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 82 | Knockout | Evl | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Evl (Ena-vasodilator stimulated phosphoprotein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: actin filament organization, actin filament-based movement, actin nucleation, actin polymerization or depolymerization, axon guidance, barbed-end actin filament capping, ... |
Does Knockout of Cul2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 83 | Knockout | Cul2 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Cul2 (cullin 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, protein catabolic process, protein ubiquitination, ubiquitin-dependent protein catabolic process, ubiquitin-dependent protein cat... |
Does Knockout of Snrpe in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 161 | Knockout | Snrpe | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Snrpe (small nuclear ribonucleoprotein E)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome, spliceosomal snRNP assembly; MF: RNA binding, U1 snRNP binding; CC: SMN-Sm protein complex, U1 snRNP, U12-type sp... |
Does Knockout of Aasdhppt in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 165 | Knockout | Aasdhppt | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Aasdhppt (aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: 10-formyltetrahydrofolate catabolic process, lysine biosynthetic process via aminoadipic acid, protein maturation; MF: holo-[acyl-carri... |
Does Knockout of Ivns1abp in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 82 | Knockout | Ivns1abp | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Ivns1abp (influenza virus NS1A binding protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, mRNA processing, negative regulation of intrinsic apoptotic signaling pathway, negative regulation of protein ubiquitination, proteasome-mediated ubiquitin-... |
Does Knockout of Topaz1 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 2,403 | Knockout | Topaz1 | protein/peptide accumulation | Embryonic Cell Line | Gene: Topaz1 (testis and ovary specific PAZ domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, cell differentiation, ectopic germ cell programmed cell death, lncRNA transcription, spermatocyte division, spermatogenesis; CC: cellular_co... |
Does Knockout of Gpr135 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,265 | Knockout | Gpr135 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Gpr135 (G protein-coupled receptor 135)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity, arrestin family protein binding; CC: endosome, endosome membrane, memb... |
Does Knockout of Ska3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,267 | Knockout | Ska3 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Ska3 (spindle and kinetochore associated complex subunit 3)
Type: protein-coding
Summary: Predicted to enable microtubule binding activity. Involved in establishment of meiotic spindle orientation and spindle assembly involved in female meiosis. Located in meiotic spindle. Is expressed in several ... |
Does Knockout of Glt1d1 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,287 | Knockout | Glt1d1 | cell proliferation | Mouse kidney carcinoma cell | Gene: Glt1d1 (glycosyltransferase 1 domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: glycosyltransferase activity, molecular_function, transferase activity; CC: cytosol, extracellular region
Pathways:
UniProt: A4FUP9
Entrez I... |
Does Knockout of Naa30 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,684 | Knockout | Naa30 | protein/peptide distribution | myoblast cell line | Gene: Naa30 (N(alpha)-acetyltransferase 30, NatC catalytic subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, protein stabilization; MF: acyltransferase activity, acyltransferase activity, transferri... |
Does Knockout of Mark2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 165 | Knockout | Mark2 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Mark2 (MAP/microtubule affinity regulating kinase 2)
Type: protein-coding
Summary: Predicted to enable several functions, including ATP binding activity; magnesium ion binding activity; and tau protein binding activity. Predicted to be involved in several processes, including generation of neurons... |
Does Knockout of Bbs4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 1,130 | Knockout | Bbs4 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Bbs4 (Bardet-Biedl syndrome 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell homeostasis, Wnt signaling pathway, adipose tissue development, adult behavior, brain morphogenesis, cell projection organization, centrosome cycle, cerebral cortex development, ci... |
Does Knockout of Npepps in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,682 | Knockout | Npepps | protein/peptide distribution | myoblast cell line | Gene: Npepps (aminopeptidase puromycin sensitive)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to hypoxia, peptide catabolic process, proteolysis; MF: alanyl aminopeptidase activity, aminopeptidase activity, hydrolase activity, metal ion binding, meta... |
Does Knockout of Sars2 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,679 | Knockout | Sars2 | protein/peptide distribution | myoblast cell line | Gene: Sars2 (seryl-aminoacyl-tRNA synthetase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial seryl-tRNA aminoacylation, seryl-tRNA aminoacylation, tRNA aminoacylation for protein translation, translation; MF: ATP binding, aminoacyl-tRNA ligase activity, l... |
Does Knockout of Pcdh17 in Embryonic Fibroblast Cell Line causally result in autophagy? | 1 | 1,044 | Knockout | Pcdh17 | autophagy | Embryonic Fibroblast Cell Line | Gene: Pcdh17 (protocadherin 17)
Type: protein-coding
Summary: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical... |
Does Knockout of Huwe1 in Embryonic Fibroblast Cell Line causally result in autophagy? | 1 | 1,044 | Knockout | Huwe1 | autophagy | Embryonic Fibroblast Cell Line | Gene: Huwe1 (HECT, UBA and WWE domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, Golgi organization, base-excision repair, canonical NF-kappaB signal transduction, cell differentiation, chromatin remodeling, circadian re... |
Does Knockout of Aggf1 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,275 | Knockout | Aggf1 | cell proliferation | Colonic Cancer Cell Line | Gene: Aggf1 (angiogenic factor with G patch and FHA domains 1)
Type: protein-coding
Summary: Predicted to enable identical protein binding activity and nucleic acid binding activity. Predicted to be involved in cell adhesion; positive regulation of angiogenesis; and positive regulation of endothelial ce... |
Does Knockout of Negr1 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,684 | Knockout | Negr1 | protein/peptide distribution | myoblast cell line | Gene: Negr1 (neuronal growth regulator 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: brain development, cell adhesion, cell-cell adhesion, cholesterol homeostasis, fat cell differentiation, feeding behavior, lipid droplet formation, locomotory behavior, negative regu... |
Does Knockout of Prepl in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,682 | Knockout | Prepl | protein/peptide distribution | myoblast cell line | Gene: Prepl (prolyl endopeptidase-like)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Golgi to plasma membrane protein transport, proteolysis, regulation of synaptic vesicle exocytosis, retrograde transport, endosome to Golgi; MF: hydrolase activity, peptidase activity,... |
Does Knockout of Ptpdc1 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,440 | Knockout | Ptpdc1 | protein/peptide accumulation | Embryonic Cell Line | Gene: Ptpdc1 (protein tyrosine phosphatase domain containing 1)
Type: protein-coding
Summary: The protein encoded by this gene is a centrosomal mitotic phosphatase. This protein has been implicated in centrosomal duplication and cytokinesis. In addition, knockdown of expression levels in non-cycling cel... |
Does Knockout of Mcat in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 1,265 | Knockout | Mcat | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Mcat (malonyl CoA:ACP acyltransferase (mitochondrial))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: fatty acid biosynthetic process, fatty acid metabolic process, lipid metabolic process, mitochondrial small ribosomal subunit assembly, monocarboxylic acid metabol... |
Does Knockout of Hadha in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,280 | Knockout | Hadha | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Hadha (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cardiolipin acyl-chain remodeling, fatty acid beta-oxidation, fatty acid metabolic process, lipid metabolic process, response to ins... |
Does Knockout of Cnga3 in Microglial Cell Line causally result in protein/peptide distribution? | 0 | 1,585 | Knockout | Cnga3 | protein/peptide distribution | Microglial Cell Line | Gene: Cnga3 (cyclic nucleotide gated channel alpha 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: calcium ion transmembrane transport, calcium ion transport, inorganic cation import across plasma membrane, membrane depolarization, monoatomic cation transmembrane trans... |
Does Knockout of Ccdc85b in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,278 | Knockout | Ccdc85b | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Ccdc85b (coiled-coil domain containing 85B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell differentiation, negative regulation of DNA-templated transcription, negative regulation of cell growth, negative regulation of fat cell differentiation; MF: delta-caten... |
Does Knockout of Fbll1 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,286 | Knockout | Fbll1 | cell proliferation | Mouse kidney carcinoma cell | Gene: Fbll1 (fibrillarin-like 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: blastocyst hatching, box C/D sno(s)RNA 3'-end processing, chromatin remodeling, mRNA stabilization, methylation, rRNA methylation, rRNA processing; MF: RNA 2'-O-methyltransferase activity, RN... |
Does Knockout of P3h3 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,264 | Knockout | P3h3 | cell proliferation | Colonic Cancer Cell Line | Gene: P3h3 (prolyl 3-hydroxylase 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: collagen biosynthetic process, collagen metabolic process, negative regulation of cell population proliferation, peptidyl-lysine hydroxylation; MF: L-ascorbic acid binding, dioxygenase act... |
Does Knockout of Lactbl1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 165 | Knockout | Lactbl1 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Lactbl1 (lactamase, beta-like 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: cellular_component, membrane
Pathways:
UniProt: S4R213
Entrez ID: 242707 |
Does Knockout of Phc3 in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 2,477 | Knockout | Phc3 | cell proliferation | Embryonic Stem Cell Line | Gene: Phc3 (polyhomeotic 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: DNA binding, chromatin binding, histone binding, metal ion binding, zinc ion binding; CC: PRC1 complex, PcG protein complex, nucleoplasm, nucleus
Pathways: Gene expression (Transcription)... |
Does Knockout of Fat1 in Malignant Peripheral Nerve Sheath Tumor (MPNST) cancer cell causally result in tumorigenicity? | 0 | 2,184 | Knockout | Fat1 | tumorigenicity | Malignant Peripheral Nerve Sheath Tumor (MPNST) cancer cell | Gene: Fat1 (FAT atypical cadherin 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: actin filament organization, anatomical structure morphogenesis, camera-type eye development, camera-type eye morphogenesis, cell adhesion, cell-cell adhesion, cell-cell adhesion mediated... |
Does Knockout of Cdkl2 in Pancreatic Cancer Cell Line causally result in response to chemicals? | 0 | 2,359 | Knockout | Cdkl2 | response to chemicals | Pancreatic Cancer Cell Line | Gene: Cdkl2 (cyclin dependent kinase like 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: ATP binding, cyclin-dependent protein serine/threonine kinase activity, kinase activity, nucleotide binding, protein kinase activity, protein serine kinase activity, protein serin... |
Does Knockout of Med12l in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,682 | Knockout | Med12l | protein/peptide distribution | myoblast cell line | Gene: Med12l (mediator complex subunit 12-like)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II; MF: beta-catenin binding, transcription coactivator activity, trans... |
Does Knockout of Usp7 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,152 | Knockout | Usp7 | protein/peptide accumulation | Embryonic Cell Line | Gene: Usp7 (ubiquitin specific peptidase 7)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA alkylation repair, DNA damage response, DNA repair, TORC1 signaling, autophagosome assembly, cellular response to nutrient levels, monoubiquitinated protein deubiquitination, n... |
Does Knockout of Duox2 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,275 | Knockout | Duox2 | cell proliferation | Colonic Cancer Cell Line | Gene: Duox2 (dual oxidase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: adenohypophysis morphogenesis, bone mineralization, cellular oxidant detoxification, cytokine-mediated signaling pathway, defense response, fertilization, hormone biosynthetic process, hormone me... |
Does Knockout of Slco2a1 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,684 | Knockout | Slco2a1 | protein/peptide distribution | myoblast cell line | Gene: Slco2a1 (solute carrier organic anion transporter family, member 2a1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: lipid transport, prostaglandin transport, sodium-independent organic anion transport, transmembrane transport; MF: lipid transporter activity, prost... |
Does Knockout of Phf23 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 82 | Knockout | Phf23 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Phf23 (PHD finger protein 23)
Type: protein-coding
Summary: Predicted to enable zinc ion binding activity. Predicted to be involved in negative regulation of autophagosome assembly; negative regulation of autophagosome maturation; and positive regulation of protein ubiquitination. Predicted to be ... |
Does Knockout of Aplnr in Mouse cell causally result in protein/peptide accumulation? | 0 | 1,047 | Knockout | Aplnr | protein/peptide accumulation | Mouse cell | Gene: Aplnr (apelin receptor)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor internalization, G protein-coupled receptor signaling pathway, adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, adult heart development, angi... |
Does Knockout of Cmas in Mouse kidney carcinoma cell causally result in cell proliferation? | 1 | 1,290 | Knockout | Cmas | cell proliferation | Mouse kidney carcinoma cell | Gene: Cmas (cytidine monophospho-N-acetylneuraminic acid synthetase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CMP-N-acetylneuraminate biosynthetic process, N-acetylneuraminate metabolic process, glycosylation; MF: N-acylneuraminate cytidylyltransferase activity, nu... |
Does Knockout of Gmps in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Gmps | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Gmps (guanine monophosphate synthetase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: GMP biosynthetic process, GMP salvage, purine nucleotide biosynthetic process, response to L-cysteine; MF: ATP binding, GMP synthase (glutamine-hydrolyzing) activity, GMP synthas... |
Does Knockout of Pde6h in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 82 | Knockout | Pde6h | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Pde6h (phosphodiesterase 6H, cGMP-specific, cone, gamma)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of G protein-coupled receptor signaling pathway, positive regulation of MAPK cascade, positive regulation of epidermal growth factor receptor... |
Does Knockout of Izumo4 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,152 | Knockout | Izumo4 | protein/peptide accumulation | Embryonic Cell Line | Gene: Izumo4 (IZUMO family member 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways: Acrosome Reaction and Sperm:Oocyte Membrane Binding, Fertilization, Reproduction
UniProt: D3Z690
Entrez ID: 71564 |
Does Knockout of Otol1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 2,307 | Knockout | Otol1 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: Otol1 (otolin 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: otolith mineralization, protein homooligomerization; MF: calcium ion binding, metal ion binding, protein binding; CC: collagen trimer, extracellular region
Pathways:
UniProt: Q4ZJM7
... |
Does Knockout of Dnah7b in Immortal mouse chromaffin cells causally result in cell viability? | 1 | 2,469 | Knockout | Dnah7b | cell viability | Immortal mouse chromaffin cells | Gene: Dnah7b (dynein, axonemal, heavy chain 7B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cilium movement, cilium movement involved in cell motility, inner dynein arm assembly, microtubule-based movement; MF: ATP binding, calcium ion binding, dynein intermediate cha... |
Does Knockout of Vmn1r205 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 165 | Knockout | Vmn1r205 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Vmn1r205 (vomeronasal 1 receptor 205)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromon... |
Does Knockout of Nsun4 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 1 | 2,307 | Knockout | Nsun4 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: Nsun4 (NOL1/NOP2/Sun domain family, member 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial RNA catabolic process, mitochondrial RNA modification, rRNA methylation, tRNA methylation; MF: RNA methyltransferase activity, mRNA (cytidine-5-)-methyltransf... |
Does Knockout of Rps14 in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation? | 1 | 2,474 | Knockout | Rps14 | protein/peptide accumulation | Embryonic Fibroblast Cell Line | Gene: Rps14 (ribosomal protein S14)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, erythrocyte differentiation, maturation of SSU-rRNA, negative regulation of transcription by RNA polymerase II, ribosomal small subunit assembly, ribosomal small s... |
Does Knockout of Tubgcp6 in Embryonic Fibroblast Cell Line causally result in response to virus? | 1 | 1,133 | Knockout | Tubgcp6 | response to virus | Embryonic Fibroblast Cell Line | Gene: Tubgcp6 (tubulin, gamma complex component 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic microtubule organization, meiotic cell cycle, microtubule cytoskeleton organization, microtubule nucleation, mitotic cell cycle, spindle assembly; MF: gamma-tubu... |
Does Knockout of Cd2bp2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Cd2bp2 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Cd2bp2 (CD2 cytoplasmic tail binding protein 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, mRNA processing; MF: ribonucleoprotein complex binding; CC: U5 snRNP, cytoplasm, cytosol, fibrillar center, nuclear speck, nucleoplasm, nucleus
Pat... |
Does Knockout of Pnkp in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 2,477 | Knockout | Pnkp | cell proliferation | Embryonic Stem Cell Line | Gene: Pnkp (polynucleotide kinase 3'- phosphatase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, double-strand break repair via nonhomologous end joining, positive regulation of double-strand break repair via nonhomologous end joining, p... |
Does Knockout of Nip7 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 1,264 | Knockout | Nip7 | cell proliferation | Colonic Cancer Cell Line | Gene: Nip7 (NIP7, nucleolar pre-rRNA processing protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ribosomal large subunit biogenesis, ribosome assembly, ribosome biogenesis; CC: cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, preribosome, large subunit precurs... |
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