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Does Knockout of Snrk in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Snrk
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Snrk (SNF related kinase) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, kinase activity, magnesium ion binding, metal ion binding, nucleotide binding, protein kinase activity, protein serine kinase activity, protein serine/threonine kinase activity, t...
Does Knockout of Psmg1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Psmg1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Psmg1 (proteasome (prosome, macropain) assembly chaperone 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cerebellar granule cell precursor proliferation, chaperone-mediated protein complex assembly, proteasome assembly, proteasome core complex assembly; MF: mole...
Does Knockout of Rad54l in Lymphoma Cell Line causally result in response to chemicals?
1
1,525
Knockout
Rad54l
response to chemicals
Lymphoma Cell Line
Gene: Rad54l (RAD54 like (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, chromosome organization, determination of adult lifespan, double-strand break repair, double-strand break repair via homologous re...
Does Knockout of Usp40 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Usp40
cell viability
Immortal mouse chromaffin cells
Gene: Usp40 (ubiquitin specific peptidase 40) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein deubiquitination, proteolysis, regulation of protein stability; MF: cysteine-type deubiquitinase activity, cysteine-type peptidase activity, hydrolase activity, peptidase...
Does Knockout of Lrrc3 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Lrrc3
protein/peptide distribution
Microglial Cell Line
Gene: Lrrc3 (leucine rich repeat containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane, plasma membrane Pathways: UniProt: P59034 Entrez ID: 237387
Does Knockout of Trerf1 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Trerf1
phagocytosis
macrophage
Gene: Trerf1 (transcriptional regulating factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to progesterone stimulus, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription, positive regulation of tr...
Does Knockout of Lrrc75a in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Lrrc75a
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Lrrc75a (leucine rich repeat containing 75A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, proteasome-mediated ubiquitin-dependent protein catabolic process; MF: molecular_function, ubiquitin-like ligase-substrate adaptor activity; CC: Cul2-RIN...
Does Knockout of Gm3055 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Gm3055
response to virus
Microglial Cell Line
Gene: Gm3055 (predicted gene 3055) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: Herpes simplex virus 1 infection - Mus musculus (mouse) UniProt: Entrez ID: 100040944
Does Knockout of Mir8094 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Mir8094
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Mir8094 (microRNA 8094) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Tas2r114 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Tas2r114
cell viability
Immortal mouse chromaffin cells
Gene: Tas2r114 (taste receptor, type 2, member 114) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of bitter taste, detection of chemical stimulus involved in sens...
Does Knockout of 1700030J22Rik in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
1700030J22Rik
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: 1700030J22Rik (RIKEN cDNA 1700030J22 gene) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytosol, nucleoplasm Pathways: UniProt: Q8BHB7 Entrez ID: 69528
Does Knockout of Kremen2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Kremen2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Kremen2 (kringle containing transmembrane protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, limb development, negative regulation of ossification, signal transduction; MF: protein binding, transmembrane signaling receptor activity; CC...
Does Knockout of Wdr1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Wdr1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Wdr1 (WD repeat domain 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, actin filament depolymerization, actin filament fragmentation, apical junction assembly, cortical cytoskeleton organization, establishment of planar polarity o...
Does Knockout of Arl13b in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Arl13b
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Arl13b (ADP-ribosylation factor-like 13B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cilium assembly, determination of left/right symmetry, dorsal/ventral pattern formation, formation of radial glial scaffolds, heart looping, interneuron migration from the subp...
Does Knockout of Mthfd2l in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Mthfd2l
protein/peptide distribution
myoblast cell line
Gene: Mthfd2l (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 10-formyltetrahydrofolate metabolic process, amino acid biosynthetic process, carboxylic acid metabolic process, methionine biosynthetic proces...
Does Knockout of Dolk in Melanoma Cell Line causally result in tumorigenicity?
0
616
Knockout
Dolk
tumorigenicity
Melanoma Cell Line
Gene: Dolk (dolichol kinase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: dolichol phosphate mannose biosynthetic process, dolichyl monophosphate biosynthetic process, lipid metabolic process, protein N-linked glycosylation; MF: dolichol kinase activity, kinase activit...
Does Knockout of Hif1a in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Hif1a
cell proliferation
Mouse kidney carcinoma cell
Gene: Hif1a (hypoxia inducible factor 1, alpha subunit) Type: protein-coding Summary: This gene encodes the alpha subunit which, along with the beta subunit, forms a heterodimeric transcription factor that regulates the cellular and developmental response to reduced oxygen tension. The transcription fac...
Does Knockout of Tnip3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Tnip3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tnip3 (TNFAIP3 interacting protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MyD88-independent toll-like receptor signaling pathway, cellular response to lipopolysaccharide, negative regulation of canonical NF-kappaB signal transduction, regulation of canon...
Does Knockout of Ddx55 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ddx55
cell proliferation
Embryonic Stem Cell Line
Gene: Ddx55 (DEAD box helicase 55) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of LSU-rRNA, rRNA processing, ribosome biogenesis; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase activity, hydrolase activity, large ribo...
Does Knockout of Clec4b1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Clec4b1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Clec4b1 (C-type lectin domain family 4, member b1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, antifungal innate immune response, immune system process, innate immune response, positive regulation of release of sequestered calcium ion i...
Does Knockout of C2cd4c in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
C2cd4c
cell proliferation
Mouse kidney carcinoma cell
Gene: C2cd4c (C2 calcium-dependent domain containing 4C) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q5HZI2 Entrez ID: 237397
Does Knockout of Cartpt in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Cartpt
cell proliferation
Colonic Cancer Cell Line
Gene: Cartpt (CART prepropeptide) Type: protein-coding Summary: This gene encodes preproprotein isoforms that are processed into multiple biologically active peptides. Expression of this gene is regulated by cocaine and other drugs, and is associated with feeding/appetite and stress response. Mice lacki...
Does Knockout of Taf12 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Taf12
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Taf12 (TATA-box binding protein associated factor 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription initiation, RNA polymerase II preinitiation complex assembly, mRNA transcription by RNA polymerase II, positive regulation of DNA-templa...
Does Knockout of Hps4 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Hps4
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Hps4 (HPS4, biogenesis of lysosomal organelles complex 3 subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blood coagulation, lysosome organization, melanocyte differentiation, melanosome assembly, platelet dense granule organization, protein stabilization,...
Does Knockout of Cdk5rap3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Cdk5rap3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cdk5rap3 (CDK5 regulatory subunit associated protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic nuclear changes, cell population proliferation, definitive erythrocyte differentiation, endoplasmic reticulum unfolded protein response, liver developme...
Does Knockout of Ube2i in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Ube2i
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ube2i (ubiquitin-conjugating enzyme E2I) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, chromosome segregation, modulation of chemical synaptic transmission, negative regulation of DNA-templated transcription, negative regulation of transcription by ...
Does Knockout of Gm28051 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Gm28051
cell proliferation
Mouse kidney carcinoma cell
Gene: Gm28051 (predicted gene, 28051) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Flad1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Flad1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Flad1 (flavin adenine dinucleotide synthetase 1) Type: protein-coding Summary: Enables FMN adenylyltransferase activity. Involved in flavin adenine dinucleotide biosynthetic process and riboflavin metabolic process. Is active in cytosol. Orthologous to human FLAD1 (flavin adenine dinucleotide synt...
Does Knockout of Fgf17 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Fgf17
protein/peptide distribution
myoblast cell line
Gene: Fgf17 (fibroblast growth factor 17) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fibroblast growth factor receptor signaling pathway, neurogenesis, positive regulation of MAPK cascade, positive regulation of cell population proliferation, regulation of cell migra...
Does Knockout of Ift43 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Ift43
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ift43 (intraflagellar transport 43) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, cilium assembly, intraciliary retrograde transport; CC: cell projection, centriolar satellite, centriole, ciliary basal body, cilium, cytoplasm, cytoske...
Does Knockout of Gbf1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Gbf1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Gbf1 (golgi-specific brefeldin A-resistance factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: COPI coating of Golgi vesicle, Golgi disassembly, Golgi organization, Golgi to endosome transport, cell activation involved in immune response, cellular response to...
Does Knockout of Rptor in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Rptor
protein/peptide accumulation
Embryonic Cell Line
Gene: Rptor (regulatory associated protein of MTOR, complex 1) Type: protein-coding Summary: This gene encodes a subunit of mammalian target of rapamycin complex 1 (mTORC1), a component of the mTOR signaling pathway, which regulates cell growth in response to nutrient and energy levels. The encoded prot...
Does Knockout of Gtf3a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Gtf3a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gtf3a (general transcription factor III A) Type: protein-coding Summary: The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50...
Does Knockout of Nol10 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Nol10
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nol10 (nucleolar protein 10) Type: protein-coding Summary: No summary available. Gene Ontology: CC: nucleolus, nucleus, small-subunit processome Pathways: UniProt: Q5RJG1 Entrez ID: 217431
Does Knockout of Psd3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Psd3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Psd3 (pleckstrin and Sec7 domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ARF protein signal transduction, regulation of ARF protein signal transduction; MF: guanyl-nucleotide exchange factor activity; CC: cell junction, cell projection, cleavag...
Does Knockout of Hoxa1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Hoxa1
cell proliferation
Embryonic Stem Cell Line
Gene: Hoxa1 (homeobox A1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: abducens nerve formation, anatomical structure formation involved in morphogenesis, anatomical structure morphogenesis, anterior/posterior pattern specification, artery development, artery morphogen...
Does Knockout of Pfdn6 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Pfdn6
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Pfdn6 (prefoldin subunit 6) Type: protein-coding Summary: Predicted to enable amyloid-beta binding activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in chaperone-mediated protein complex assembly; negative regulation of amyloid fi...
Does Knockout of Edem1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Edem1
protein/peptide accumulation
Embryonic Cell Line
Gene: Edem1 (ER degradation enhancer, mannosidase alpha-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, carbohydrate metabolic process, endoplasmic reticulum mannose trimming, positive regulation of retrograde protein transport, ER to cytosol, protei...
Does Knockout of Hyal1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Hyal1
cell proliferation
Embryonic Stem Cell Line
Gene: Hyal1 (hyaluronoglucosaminidase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate metabolic process, cartilage development, cellular response to UV-B, cellular response to fibroblast growth factor stimulus, cellular response to interleukin-1, cellular ...
Does Knockout of Cdc14b in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Cdc14b
protein/peptide distribution
myoblast cell line
Gene: Cdc14b (CDC14 cell division cycle 14B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, cilium assembly, microtubule cytoskeleton organization, mitotic G2 DNA damage checkpoint signaling, positive regulation of cytokinesis, positive r...
Does Knockout of Ankle2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ankle2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ankle2 (ankyrin repeat and LEM domain containing 2) Type: protein-coding Summary: Predicted to enable protein kinase inhibitor activity and protein phosphatase 2A binding activity. Predicted to be involved in several processes, including mitotic nuclear membrane reassembly; negative regulation of ...
Does Knockout of Rpl31 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Rpl31
response to virus
Microglial Cell Line
Gene: Rpl31 (ribosomal protein L31) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, translation; MF: protein binding, structural constituent of ribosome; CC: cytoplasm, cytosol, cytosolic large ribosomal subunit, cytosolic ribosome, large ribosoma...
Does Knockout of Akirin2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Akirin2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Akirin2 (akirin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, cerebral cortex development, defense response to bacterium, embryo development ending in birth or egg hatching, immune system process, innate immune response, negative regul...
Does Knockout of Snrpa1 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Snrpa1
protein/peptide distribution
Microglial Cell Line
Gene: Snrpa1 (small nuclear ribonucleoprotein polypeptide A') Type: protein-coding Summary: Predicted to enable U2 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome and spermatogenesis. Predicted to be located in nuclear speck. Predicted to be part of U2 snRNP; U2-type c...
Does Knockout of Fadd in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Fadd
protein/peptide distribution
myoblast cell line
Gene: Fadd (Fas associated via death domain) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell differentiation, T cell differentiation in thymus, T cell homeostasis, TRAIL-activated apoptotic signaling pathway, apoptotic process, apoptotic signaling pathway, behavior...
Does Knockout of Pcdhb16 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Pcdhb16
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pcdhb16 (protocadherin beta 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, cell adhesion, chemical synaptic transmission, homophilic cell adhesion via plasma membrane adhesion mol...
Does Knockout of Npr2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Npr2
cell proliferation
Mouse kidney carcinoma cell
Gene: Npr2 (natriuretic peptide receptor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, activation of meiosis involved in egg activation, axonogenesis, axonogenesis involved in innervation, blood circulation, blood vessel development, blood vessel remode...
Does Knockout of Blcap in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Blcap
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Blcap (bladder cancer associated protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic nuclear changes, apoptotic process, biological_process; CC: cytoplasm, membrane, nucleus Pathways: UniProt: P62951 Entrez ID: 53619
Does Knockout of Actb in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Actb
cell proliferation
Embryonic Stem Cell Line
Gene: Actb (actin, beta) Type: protein-coding Summary: This gene encodes a member of the actin family of proteins. Actins are highly conserved proteins that are among the most abundant proteins in eukaryotic cells and are involved in cell motility, structure, and integrity. Localization, stability, and ...
Does Knockout of Ppp1cb in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Ppp1cb
protein/peptide distribution
Microglial Cell Line
Gene: Ppp1cb (protein phosphatase 1 catalytic subunit beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, circadian regulation of gene expression, entrainment of circadian clock by photoperiod, glycogen metabolic process, protein dephosphorylation, regula...
Does Knockout of Enkur in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Enkur
cell proliferation
Mouse kidney carcinoma cell
Gene: Enkur (enkurin, TRPC channel interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: establishment of left/right asymmetry, flagellated sperm motility; MF: SH3 domain binding, calmodulin binding, protein binding; CC: 9+0 motile cilium, 9+2 motile cilium...
Does Knockout of Mphosph6 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Mphosph6
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mphosph6 (M phase phosphoprotein 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of 5.8S rRNA, rRNA processing; MF: RNA binding, molecular_function; CC: cytoplasm, cytosol, exosome (RNase complex), nuclear exosome (RNase complex), nucleolus, nucleoplas...
Does Knockout of Hars2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Hars2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Hars2 (histidyl-tRNA synthetase 2) Type: protein-coding Summary: This gene encodes a putative member of the class II family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuc...
Does Knockout of Sestd1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Sestd1
cell proliferation
Mouse kidney carcinoma cell
Gene: Sestd1 (SEC14 and spectrin domains 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel; MF: phosphatidic acid binding, phosphatidylinositol-3,4-bisphosphate binding, pho...
Does Knockout of Gm13271 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Gm13271
protein/peptide accumulation
Embryonic Cell Line
Gene: Gm13271 (predicted gene 13271) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation involved in immune response, T cell activation involved in immune response, adaptive immune response, defense response, defense response to virus, humoral immune respons...
Does Knockout of Il4ra in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Il4ra
autophagy
Embryonic Fibroblast Cell Line
Gene: Il4ra (interleukin 4 receptor, alpha) Type: protein-coding Summary: Predicted to enable interleukin-4 receptor activity. Involved in positive regulation of chemokine production; positive regulation of cold-induced thermogenesis; and positive regulation of macrophage activation. Acts upstream of or...
Does Knockout of Rfx8 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Rfx8
cell proliferation
Mouse kidney carcinoma cell
Gene: Rfx8 (regulatory factor X 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor act...
Does Knockout of Myl12a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Myl12a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Myl12a (myosin, light chain 12A, regulatory, non-sarcomeric) Type: protein-coding Summary: Enables glutamate receptor binding activity. Acts upstream of or within protein localization to plasma membrane and regulation of cell shape. Located in Z disc and stress fiber. Part of myosin II complex. Or...
Does Knockout of Camk1g in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Camk1g
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Camk1g (calcium/calmodulin-dependent protein kinase I gamma) Type: protein-coding Summary: Enables calcium/calmodulin-dependent protein kinase activity. Predicted to be involved in signal transduction. Located in endomembrane system and plasma membrane. Part of calcium- and calmodulin-dependent pr...
Does Knockout of Kif20a in macrophage causally result in phagocytosis?
0
1,888
Knockout
Kif20a
phagocytosis
macrophage
Gene: Kif20a (kinesin family member 20A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule bundle formation, microtubule-based movement, midbody abscission, mitotic cytokinesis, protein transport, regulation of cytokinesis; MF: ATP binding, ATP hydrolysis activi...
Does Knockout of Tiprl in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Tiprl
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Tiprl (TIP41, TOR signalling pathway regulator-like (S. cerevisiae)) Type: protein-coding Summary: Predicted to enable protein phosphatase activator activity. Predicted to be involved in DNA damage checkpoint signaling and TOR signaling. Predicted to be located in cytoplasm. Predicted to be active...
Does Knockout of Slc38a11 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Slc38a11
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Slc38a11 (solute carrier family 38, member 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-alpha-amino acid transmembrane transport, amino acid transmembrane transport, amino acid transport, monoatomic ion transport, sodium ion transport; CC: membrane ...
Does Knockout of Eme1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Eme1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Eme1 (essential meiotic structure-specific endonuclease 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, double-strand break repair, mitotic intra-S DNA damage checkpoint signaling, replication fork processing, r...
Does Knockout of Supt6 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Supt6
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Supt6 (SPT6, histone chaperone and transcription elongation factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, blastocyst formation, mRNA processing, mRNA transport, nucleobase-containing compound metabolic process, nucleosome organization, positi...
Does Knockout of Kl in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Kl
cell viability
Immortal mouse chromaffin cells
Gene: Kl (klotho) Type: protein-coding Summary: Enables fibroblast growth factor binding activity and fibroblast growth factor receptor binding activity. Acts upstream of or within several processes, including determination of adult lifespan; energy reserve metabolic process; and positive regulation of ...
Does Knockout of Brcc3 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Brcc3
protein/peptide distribution
myoblast cell line
Gene: Brcc3 (BRCA1/BRCA2-containing complex, subunit 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, NLRP3 inflammasome complex assembly, cell division, cellular response to ionizing radiation,...
Does Knockout of Pcdhb3 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Pcdhb3
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Pcdhb3 (protocadherin beta 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding; CC: membrane, plasma membrane Pathways: ...
Does Knockout of Xylb in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Xylb
protein/peptide accumulation
Embryonic Cell Line
Gene: Xylb (xylulokinase homolog (H. influenzae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-glucuronate catabolic process to D-xylulose 5-phosphate, D-xylose metabolic process, carbohydrate metabolic process, carbohydrate phosphorylation, xylulose metabolic proces...
Does Knockout of Cdk5rap1 in Melanoma Cell Line causally result in cell proliferation?
1
2,492
Knockout
Cdk5rap1
cell proliferation
Melanoma Cell Line
Gene: Cdk5rap1 (CDK5 regulatory subunit associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA modification, mitochondrial tRNA modification, negative regulation of cyclin-dependent protein serine/threonine kinase activity, positive regulation of mitoch...
Does Knockout of Etv5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Etv5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Etv5 (ets variant 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cellular response to oxidative stress, locomotory behavior, male germ-line stem cell asymmetric division, negative regulation of transcription by RNA polymerase II, neuromuscu...
Does Knockout of Cilp in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Cilp
cell proliferation
Mouse kidney carcinoma cell
Gene: Cilp (cartilage intermediate layer protein, nucleotide pyrophosphohydrolase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of SMAD protein signal transduction, negative regulation of gene expression, negative regulation of insulin-like growth f...
Does Knockout of Bloc1s4 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Bloc1s4
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Bloc1s4 (biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino) Type: protein-coding Summary: Involved in anterograde synaptic vesicle transport. Acts upstream of or within melanosome organization; neuromuscular process controlling balance; and platelet aggregation. Located in cytopl...
Does Knockout of Nyap1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Nyap1
cell proliferation
Colonic Cancer Cell Line
Gene: Nyap1 (neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: neuron projection morphogenesis, phosphatidylinositol 3-kinase/protein kinase B signal transduction Pathways: UniProt: Q6P...
Does Knockout of A130010J15Rik in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
A130010J15Rik
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: A130010J15Rik (RIKEN cDNA A130010J15 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9DAE8 Entrez ID: 319266
Does Knockout of Rbks in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Rbks
cell cycle progression
breast epithelium
Gene: Rbks (ribokinase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-ribose catabolic process, D-ribose metabolic process, carbohydrate phosphorylation, pentose-phosphate shunt; MF: ATP binding, identical protein binding, kinase activity, metal ion binding, nucleotid...
Does Knockout of Orc3 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Orc3
cell proliferation
Colonic Cancer Cell Line
Gene: Orc3 (origin recognition complex, subunit 3) Type: protein-coding Summary: Predicted to enable DNA replication origin binding activity. Acts upstream of or within glial cell proliferation and neural precursor cell proliferation. Predicted to be located in chromatin and nuclear body. Predicted to b...
Does Knockout of Ccnl2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ccnl2
cell proliferation
Embryonic Stem Cell Line
Gene: Ccnl2 (cyclin L2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of RNA splicing, regulation of apoptotic process, regulation of cell cycle, regulation of centrosome cycle, regulation of transcription by RNA polymerase II; MF: cyclin-dependent protein se...
Does Knockout of Chgb in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Chgb
protein/peptide accumulation
Embryonic Cell Line
Gene: Chgb (chromogranin B) Type: protein-coding Summary: No summary available. Gene Ontology: CC: extracellular region, extracellular space, secretory granule Pathways: Metabolism of proteins, Post-translational protein modification, Post-translational protein phosphorylation, Regulat...
Does Knockout of Nfs1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Nfs1
cell proliferation
Embryonic Stem Cell Line
Gene: Nfs1 (nitrogen fixation gene 1 (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Mo-molybdopterin cofactor biosynthetic process, [2Fe-2S] cluster assembly, [4Fe-4S] cluster assembly, iron-sulfur cluster assembly, molybdopterin cofactor biosynthetic pr...
Does Knockout of Rpl17 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Rpl17
protein/peptide distribution
myoblast cell line
Gene: Rpl17 (ribosomal protein L17) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to amino acid starvation, cytoplasmic translation, positive regulation of G1/S transition of mitotic cell cycle, response to amino acid starvation, translation, translati...
Does Knockout of Slc2a8 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Slc2a8
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Slc2a8 (solute carrier family 2, (facilitated glucose transporter), member 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-glucose transmembrane transport, dehydroascorbic acid transport, fructose transmembrane transport, galactose transmembrane transport, gluc...
Does Knockout of 4921536K21Rik in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
4921536K21Rik
protein/peptide distribution
myoblast cell line
Gene: 4921536K21Rik (RIKEN cDNA 4921536K21 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9CR34 Entrez ID: 67430
Does Knockout of Eif5a in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Eif5a
cell proliferation
Embryonic Stem Cell Line
Gene: Eif5a (eukaryotic translation initiation factor 5A) Type: protein-coding Summary: This gene encodes an elongation initiation factor, which participates in protein synthesis. The encoded protein also plays roles in mRNA metabolism, cell proliferation, and cell cycle control. This protein contains a...
Does Knockout of D7Ertd443e in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
D7Ertd443e
protein/peptide distribution
myoblast cell line
Gene: D7Ertd443e (DNA segment, Chr 7, ERATO Doi 443, expressed) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, mitotic G2 DNA damage checkpoint signaling, negative regulation of cell growth, protein polyubiquitination, protein stabilization, protein ...
Does Knockout of Pitpna in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Pitpna
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Pitpna (phosphatidylinositol transfer protein, alpha) Type: protein-coding Summary: This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signal...
Does Knockout of Zmym5 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Zmym5
protein/peptide distribution
myoblast cell line
Gene: Zmym5 (zinc finger, MYM-type 5) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, zinc ion binding Pathways: UniProt: Q3U2E2 Entrez ID: 219105
Does Knockout of Zfp595 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Zfp595
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Zfp595 (zinc finger protein 595) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: metal ion binding, sequence-s...
Does Knockout of Ngdn in Embryonic Stem Cell Line causally result in cell proliferation?
1
578
Knockout
Ngdn
cell proliferation
Embryonic Stem Cell Line
Gene: Ngdn (neuroguidin, EIF4E binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), negative regulation of protein localization to plasma membrane, postsynaptic modulatio...
Does Knockout of Aamp in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Aamp
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Aamp (angio-associated migratory protein) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cell surface, cytoplasm, intercellular bridge, microtubule cytoskeleton, plasma membrane Pathways: Hemostasis, Immune System, Innate Immune System, NOD1/2 Signaling Pa...
Does Knockout of Krtap5-1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Krtap5-1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Krtap5-1 (keratin associated protein 5-1) Type: protein-coding Summary: Predicted to enable identical protein binding activity. Predicted to be located in intermediate filament. Orthologous to human KRTAP5-2 (keratin associated protein 5-2) and KRTAP5-5 (keratin associated protein 5-5). [provided ...
Does Knockout of Krt7 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Krt7
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Krt7 (keratin 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intermediate filament organization, keratinization; MF: protein binding, structural constituent of skin epidermis; CC: cytoplasm, cytosol, intermediate filament, intermediate filament cytoskeleton, ker...
Does Knockout of Prm2 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Prm2
protein/peptide distribution
myoblast cell line
Gene: Prm2 (protamine 2) Type: protein-coding Summary: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis, and are the major DNA-binding proteins in the nucleus of sperm in many vertebrates. They package the sperm DNA into a highly condensed complex ...
Does Knockout of Ilkap in macrophage causally result in phagocytosis?
0
1,888
Knockout
Ilkap
phagocytosis
macrophage
Gene: Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of nuclear cell cycle DNA replication, signal transduction; MF: cation binding, hydrolase activity, metal ion binding, phosphoprotein...
Does Knockout of Fabp6 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Fabp6
cell viability
Immortal mouse chromaffin cells
Gene: Fabp6 (fatty acid binding protein 6) Type: protein-coding Summary: The protein encoded by this gene is part of the fatty acid binding protein family (FABP). FABPs are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands and partic...
Does Knockout of Daw1 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Daw1
cell cycle progression
breast epithelium
Gene: Daw1 (dynein assembly factor with WDR repeat domains 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axonemal dynein complex assembly, cerebrospinal fluid circulation, determination of left/right symmetry, epithelial cilium movement involved in extracellular flui...
Does Knockout of Pam in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Pam
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Pam (peptidylglycine alpha-amidating monooxygenase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to oxidative stress, fatty acid primary amide biosynthetic process, lipid metabolic process, long-chain fatty acid metabolic process, peptide amidat...
Does Knockout of Alx3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Alx3
cell proliferation
Mouse kidney carcinoma cell
Gene: Alx3 (aristaless-like homeobox 3) Type: protein-coding Summary: This gene belongs to Group 1 of aristaless-like genes, which are characterized by the presence of an aristaless domain and a conserved paired-like homeodomain. The encoded protein acts as a transcriptional regulator. The protein plays...
Does Knockout of Vps39 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Vps39
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Vps39 (VPS39 HOPS complex subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome-lysosome fusion, autophagy, endocytic recycling, endosomal vesicle fusion, endosome to lysosome transport, intracellular protein transport, late endosome to lysosome tra...
Does Knockout of Csf2rb in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Csf2rb
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Csf2rb (colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway via JAK-STAT, cytokine-mediated signaling pathway, granulocyte-macrophage colony-stimul...
Does Knockout of Mcts1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Mcts1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Mcts1 (malignant T cell amplified sequence 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, IRES-dependent viral translational initiation, formation of translation preinitiation complex, ribosome disassembly, translation, translation reinitiat...