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Does Knockout of Sectm1a in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Sectm1a
cell proliferation
Embryonic Stem Cell Line
Gene: Sectm1a (secreted and transmembrane 1A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: immune response, interleukin-2-mediated signaling pathway, positive regulation of T cell cytokine production, signal transduction; MF: cytokine activity, receptor ligand activity...
Does Knockout of Lilra5 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Lilra5
response to chemicals
Pancreatic Cancer Cell Line
Gene: Lilra5 (leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway, cytokine-mediated signaling pathway, immune response-regulating signaling pathway, negati...
Does Knockout of Oc90 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Oc90
phagocytosis
macrophage
Gene: Oc90 (otoconin 90) Type: protein-coding Summary: No summary available. Gene Ontology: BP: arachidonate secretion, lipid catabolic process, otolith mineralization, phosphatidylcholine metabolic process, phosphatidylglycerol metabolic process, phospholipid metabolic process; MF: calcium ion...
Does Knockout of 4930447C04Rik in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
4930447C04Rik
response to virus
Microglial Cell Line
Gene: 4930447C04Rik (RIKEN cDNA 4930447C04 gene) Type: protein-coding Summary: Involved in meiosis I; oogenesis; and spermatogenesis. Located in central element. Is expressed in several structures, including genitourinary system; intestine; liver; lung; and retina. Human ortholog(s) of this gene implica...
Does Knockout of Vwc2 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Vwc2
protein/peptide distribution
myoblast cell line
Gene: Vwc2 (von Willebrand factor C domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of BMP signaling pathway, neurotransmitter receptor localization to postsynaptic specialization membrane, positive regulation of cell-substrate adh...
Does Knockout of Cwc25 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Cwc25
protein/peptide accumulation
Embryonic Cell Line
Gene: Cwc25 (CWC25 spliceosome-associated protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome; CC: U2-type catalytic step 1 spliceosome, U2-type spliceosomal complex, nuclear speck, nucleus, spliceosomal c...
Does Knockout of Ifnar2 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Ifnar2
cell proliferation
Colonic Cancer Cell Line
Gene: Ifnar2 (interferon (alpha and beta) receptor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway via JAK-STAT, cellular response to interferon-beta, defense response to virus, immature T cell proliferation in thymus, positive r...
Does Knockout of Polr1a in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Polr1a
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Polr1a (polymerase (RNA) I polypeptide A) Type: protein-coding Summary: Predicted to enable DNA/RNA hybrid binding activity; chromatin binding activity; and metal ion binding activity. Predicted to contribute to DNA-directed RNA polymerase activity. Predicted to be involved in negative regulation ...
Does Knockout of Amd2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Amd2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Amd2 (S-adenosylmethionine decarboxylase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: S-adenosylmethionine metabolic process, polyamine biosynthetic process, polyamine metabolic process, spermidine biosynthetic process, spermine biosynthetic process; MF: adeno...
Does Knockout of Foxa3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Foxa3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Foxa3 (forkhead box A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anatomical structure morphogenesis, cell differentiation, cellular response to starvation, chromatin organization, glucose homeostasis, hematopoietic stem cell homeostasis, intracellular glucose...
Does Knockout of Pole2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Pole2
cell proliferation
Embryonic Stem Cell Line
Gene: Pole2 (polymerase (DNA directed), epsilon 2 (p59 subunit)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA metabolic process, DNA replication, DNA-templated DNA replication, error-prone translesion synthesis; CC: chromosome, epsilon DNA polymerase complex, nucle...
Does Knockout of Rmnd5a in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Rmnd5a
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Rmnd5a (required for meiotic nuclear division 5 homolog A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, protein polyubiquitination; MF: metal ion binding, transferase activity, ubiquitin protein l...
Does Knockout of Scamp2 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Scamp2
protein/peptide distribution
myoblast cell line
Gene: Scamp2 (secretory carrier membrane protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: exocytosis, protein transport; CC: Golgi apparatus, endosome, membrane, recycling endosome membrane, trans-Golgi network membrane Pathways: UniProt: Q9ER...
Does Knockout of Ndufv2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ndufv2
cell proliferation
Embryonic Stem Cell Line
Gene: Ndufv2 (NADH:ubiquinone oxidoreductase core subunit V2) Type: protein-coding Summary: This gene encodes a subunit of the NADH-ubiquinone oxidoreductase (complex I) enzyme, which is a large, multimeric protein. It is the first enzyme complex in the mitochondrial electron transport chain and catalyz...
Does Knockout of Rasa1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Rasa1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Rasa1 (RAS p21 protein activator 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, blood vessel morphogenesis, cellular response to epidermal growth factor stimulus, cellular response to platelet-derived growth factor stimulus, ephrin receptor signali...
Does Knockout of Atad2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,174
Knockout
Atad2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Atad2 (ATPase family, AAA domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nucleosome assembly, nucleosome disassembly, positive regulation of DNA-templated transcription, transcription initiation-coupled chromatin remodeling; MF: ATP binding, AT...
Does Knockout of Pold2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Pold2
cell viability
Immortal mouse chromaffin cells
Gene: Pold2 (polymerase (DNA directed), delta 2, regulatory subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA biosynthetic process, DNA damage response, DNA metabolic process, DNA repair, DNA replication, DNA strand elongation involved in DNA replication, DNA-t...
Does Knockout of Plekho1 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Plekho1
protein/peptide distribution
myoblast cell line
Gene: Plekho1 (pleckstrin homology domain containing, family O member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lamellipodium morphogenesis, myoblast fusion, myoblast migration, regulation of cell shape, regulation of myoblast fusion; CC: cytoplasm, membrane, mus...
Does Knockout of Rbm47 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Rbm47
cell proliferation
Mouse kidney carcinoma cell
Gene: Rbm47 (RNA binding motif protein 47) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 3'-UTR-mediated mRNA stabilization, RNA splicing, cytidine to uridine editing, hematopoietic progenitor cell differentiation, low-density lipoprotein particle clearance, mRNA proces...
Does Knockout of Eif2b4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Eif2b4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Eif2b4 (eukaryotic translation initiation factor 2B, subunit 4 delta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell receptor signaling pathway, animal organ development, central nervous system development, cytoplasmic translational initiation, myelination, ...
Does Knockout of Stk11 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Stk11
cell proliferation
Mouse kidney carcinoma cell
Gene: Stk11 (serine/threonine kinase 11) Type: protein-coding Summary: This gene encodes a member of the serine/threonine kinase family. The encoded protein, a known tumor suppressor, activates (via phosphorylation) adenine monophosphate-activated protein kinase (AMPK) and AMPK-related kinase proteins. ...
Does Knockout of Mlxip in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Mlxip
protein/peptide accumulation
Embryonic Cell Line
Gene: Mlxip (MLX interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nucleocytoplasmic transport, positive regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-bin...
Does Knockout of D630023F18Rik in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
D630023F18Rik
response to virus
Embryonic Fibroblast Cell Line
Gene: D630023F18Rik (RIKEN cDNA D630023F18 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8C3M9 Entrez ID: 98303
Does Knockout of Ctnna3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Ctnna3
cell proliferation
Mouse kidney carcinoma cell
Gene: Ctnna3 (catenin alpha 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bundle of His cell-Purkinje myocyte adhesion involved in cell communication, cell adhesion, cell migration, cell-cell adhesion, regulation of heart rate by cardiac conduction, regulation of ven...
Does Knockout of Sstr2 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Sstr2
protein/peptide accumulation
Mouse cell
Gene: Sstr2 (somatostatin receptor 2) Type: protein-coding Summary: The protein encoded by this gene is a receptor for somatostatin, which acts at many sites to inhibit the release of several hormones and other secretory proteins. The encoded protein is a member of the superfamily of receptors having se...
Does Knockout of Fbxo2 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Fbxo2
protein/peptide distribution
myoblast cell line
Gene: Fbxo2 (F-box protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, glycoprotein catabolic process, negative regulation of cell population proliferation, protein ubiquitinatio...
Does Knockout of Vti1a in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Vti1a
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Vti1a (vesicle transport through interaction with t-SNAREs 1A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to vacuole transport, autophagy, endocytic recycling, endoplasmic reticulum to Golgi vesicle-mediated transport, endosomal transport, intra-Golgi ves...
Does Knockout of Iglon5 in Melanoma Cell Line causally result in cell proliferation?
1
2,492
Knockout
Iglon5
cell proliferation
Melanoma Cell Line
Gene: Iglon5 (IgLON family member 5) Type: protein-coding Summary: Acts upstream of or within motor behavior and neuromuscular process controlling balance. Predicted to be located in extracellular region. Is expressed in central nervous system; peripheral nervous system ganglion; and sensory organ. Orth...
Does Knockout of Strn3 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Strn3
protein/peptide accumulation
Embryonic Cell Line
Gene: Strn3 (striatin, calmodulin binding protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, negative regulation of hippo signaling, negative regulation of intracellular estrogen receptor signaling pathway, negat...
Does Knockout of Zranb1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Zranb1
autophagy
Embryonic Fibroblast Cell Line
Gene: Zranb1 (zinc finger, RAN-binding domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, autophagosome assembly, cell migration, cytoskeleton organization, phosphatidylinositol phosphate biosynthetic process, positive regulation o...
Does Knockout of Rai14 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Rai14
protein/peptide distribution
myoblast cell line
Gene: Rai14 (retinoic acid induced 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, spermatogenesis; CC: anchoring junction, cell cortex, cytoplasm, cytoskeleton, cytosol, fibrillar center, mitochondrion, nucleoplasm, nucleus, stress fiber ...
Does Knockout of Chmp4b in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Chmp4b
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Chmp4b (charged multivesicular body protein 4B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome maturation, autophagy, exit from mitosis, late endosome to lysosome transport, late endosome to vacuole transport via multivesicular body sorting pathway, m...
Does Knockout of Tmem92 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Tmem92
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Tmem92 (transmembrane protein 92) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane, nucleoplasm Pathways: UniProt: B7ZWI3 Entrez ID: 544806
Does Knockout of Tmco3 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Tmco3
protein/peptide distribution
myoblast cell line
Gene: Tmco3 (transmembrane and coiled-coil domains 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, monoatomic cation transport, monoatomic ion transport, potassium ion transmembrane transport, proton transmembrane transport, transmembrane transport;...
Does Knockout of Slc25a19 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Slc25a19
cell proliferation
Colonic Cancer Cell Line
Gene: Slc25a19 (solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19) Type: protein-coding Summary: Enables thiamine pyrophosphate transmembrane transporter activity. Involved in thiamine diphosphate biosynthetic process. Located in mitochondrion. Is active in mitochondrial...
Does Knockout of Vmn2r80 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Vmn2r80
protein/peptide accumulation
Embryonic Cell Line
Gene: Vmn2r80 (vomeronasal 2, receptor 80) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, regulation of calcium ion transport, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane ...
Does Knockout of Gpr4 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Gpr4
cell proliferation
Melanoma Cell Line
Gene: Gpr4 (G protein-coupled receptor 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, angiogenesis involved in wound healing, cellular response to ...
Does Knockout of Rnf157 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Rnf157
protein/peptide distribution
myoblast cell line
Gene: Rnf157 (ring finger protein 157) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of apoptotic process, positive regulation of dendrite extension, protein ubiquitination; MF: metal ion binding, protein binding, transferase activity, ubiquitin prot...
Does Knockout of I830077J02Rik in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
I830077J02Rik
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: I830077J02Rik (RIKEN cDNA I830077J02 gene) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q3U7U4 Entrez ID: 433638
Does Knockout of Siae in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Siae
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Siae (sialic acid acetylesterase) Type: protein-coding Summary: Predicted to enable sialate O-acetylesterase activity. Predicted to be involved in carbohydrate metabolic process and regulation of immune system process. Located in lysosome. Is expressed in several structures, including abdominal fa...
Does Knockout of E030030I06Rik in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
E030030I06Rik
protein/peptide accumulation
Mouse cell
Gene: E030030I06Rik (RIKEN cDNA E030030I06 gene) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Copb1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Copb1
protein/peptide distribution
myoblast cell line
Gene: Copb1 (coatomer protein complex, subunit beta 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endoplasmic reticulum to Golgi vesicle-mediated transport, intra-Golgi vesicle-mediated transport, intracellular protein transport, protein transport, vesicle-mediated t...
Does Knockout of Tbx3 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Tbx3
protein/peptide distribution
myoblast cell line
Gene: Tbx3 (T-box 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ morphogenesis, anterior/posterior axis specification, embryo, atrioventricular bundle cell differentiation, atrioventricular canal development, atrioventricular canal morphogenesis, blood ve...
Does Knockout of Mc4r in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Mc4r
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Mc4r (melanocortin 4 receptor) Type: protein-coding Summary: This gene encodes a member of the melanocortin receptor family. Melanocortin receptors are transmembrane G-protein coupled receptors, which respond to small peptide hormones and exhibit diverse functions and tissue type localization. As ...
Does Knockout of Ltk in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Ltk
autophagy
Embryonic Fibroblast Cell Line
Gene: Ltk (leukocyte tyrosine kinase) Type: protein-coding Summary: The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specific phosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation. F...
Does Knockout of Msmo1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Msmo1
cell proliferation
Mouse kidney carcinoma cell
Gene: Msmo1 (methylsterol monoxygenase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cholesterol biosynthetic process, cholesterol biosynthetic process via desmosterol, cholesterol biosynthetic process via lathosterol, cholesterol metabolic process, lipid biosyntheti...
Does Knockout of Mtpap in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Mtpap
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mtpap (mitochondrial poly(A) polymerase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA 3'-end processing, RNA metabolic process, histone mRNA catabolic process, mRNA processing, mitochondrial RNA 3'-end processing, mitochondrial mRNA polyadenylation; MF: ATP b...
Does Knockout of Acadvl in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Acadvl
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Acadvl (acyl-Coenzyme A dehydrogenase, very long chain) Type: protein-coding Summary: This gene encodes a homodimeric mitochondrial flavoprotein and is a member of the acyl-CoA dehydrogenase family. Members of this family catalyze the first step of fatty acid beta-oxidation, forming a C2-C3 trans-...
Does Knockout of Phf23 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Phf23
response to virus
Embryonic Fibroblast Cell Line
Gene: Phf23 (PHD finger protein 23) Type: protein-coding Summary: Predicted to enable zinc ion binding activity. Predicted to be involved in negative regulation of autophagosome assembly; negative regulation of autophagosome maturation; and positive regulation of protein ubiquitination. Predicted to be ...
Does Knockout of Smox in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Smox
cell proliferation
Mouse kidney carcinoma cell
Gene: Smox (spermine oxidase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: polyamine catabolic process, spermine catabolic process; MF: oxidoreductase activity, polyamine oxidase activity, spermine oxidase activity; CC: cytoplasm, cytosol, nuclear membrane, nucleoplasm...
Does Knockout of Setd3 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Setd3
response to virus
Microglial Cell Line
Gene: Setd3 (SET domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin modification, chromatin remodeling, methylation, peptidyl-histidine methylation, positive regulation of DNA-templated transcription, positive regulation of muscle cell differentiat...
Does Knockout of Dbf4 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Dbf4
cell proliferation
Melanoma Cell Line
Gene: Dbf4 (DBF4 zinc finger) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, positive regulation of nuclear cell cycle DNA replication, regulation of cell cycle phase transition, traversing start control point of mitotic cell cycle; MF: metal ion binding...
Does Knockout of Extl2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Extl2
protein/peptide accumulation
Embryonic Cell Line
Gene: Extl2 (exostosin-like glycosyltransferase 2) Type: protein-coding Summary: Enables acetylgalactosaminyltransferase activity; glycosaminoglycan binding activity; and manganese ion binding activity. Involved in N-acetylglucosamine metabolic process and UDP-N-acetylgalactosamine metabolic process. Pr...
Does Knockout of Pcdha5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Pcdha5
cell proliferation
Mouse kidney carcinoma cell
Gene: Pcdha5 (protocadherin alpha 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding; CC: membrane, plasma membrane Pathways: ...
Does Knockout of Ranbp3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ranbp3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ranbp3 (RAN binding protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein export from nucleus, protein transport; CC: cytoplasm, nucleoplasm, nucleus Pathways: Human T-cell leukemia virus 1 infection - Mus musculus (mouse) UniProt: Q9C...
Does Knockout of Zfp300 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Zfp300
protein/peptide distribution
myoblast cell line
Gene: Zfp300 (zinc finger protein 300) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of macromolecule biosynthetic process, regulation of DNA-templated transcription; MF: DNA binding, metal ion binding, zinc ion binding Pathways: Herpes simp...
Does Knockout of Ccdc69 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Ccdc69
protein/peptide accumulation
Embryonic Cell Line
Gene: Ccdc69 (coiled-coil domain containing 69) Type: protein-coding Summary: No summary available. Gene Ontology: BP: spindle midzone assembly; CC: cytoplasm, cytoskeleton, midbody, nucleus, spindle, spindle midzone Pathways: UniProt: Q3TCJ8 Entrez ID: 52570
Does Knockout of Ahcy in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Ahcy
cell proliferation
Colonic Cancer Cell Line
Gene: Ahcy (S-adenosylhomocysteine hydrolase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: S-adenosylhomocysteine catabolic process, S-adenosylmethionine cycle, S-methylmethionine cycle, chronic inflammatory response to antigenic stimulus, circadian sleep/wake cycle, o...
Does Knockout of Emsy in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Emsy
cell cycle progression
breast epithelium
Gene: Emsy (EMSY, BRCA2-interacting transcriptional repressor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, chromatin organization, regulation of DNA-templated transcription; MF: identical protein binding, protein binding; CC: nucleopla...
Does Knockout of Wnt7b in Regulatory T cell causally result in protein/peptide accumulation?
1
1,482
Knockout
Wnt7b
protein/peptide accumulation
Regulatory T cell
Gene: Wnt7b (wingless-type MMTV integration site family, member 7B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, Wnt signaling pathway, planar cell polarity pathway, anatomical structure regression, angiogenesis, animal organ morphogenesis, apopt...
Does Knockout of Zxdc in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Zxdc
cell proliferation
Embryonic Stem Cell Line
Gene: Zxdc (ZXD family zinc finger C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: C2H2 zinc finger domain binding, LRR domain binding, metal ion binding, transcri...
Does Knockout of Cecr2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Cecr2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cecr2 (CECR2, histone acetyl-lysine reader) Type: protein-coding Summary: Predicted to enable ATP-dependent chromatin remodeler activity. Acts upstream of or within inner ear development; primary neural tube formation; and single fertilization. Located in euchromatin and nucleus. Part of CERF comp...
Does Knockout of Traf4 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Traf4
protein/peptide distribution
Microglial Cell Line
Gene: Traf4 (TNF receptor associated factor 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cell surface receptor signaling pathway, immune system process, innate immune response, positive regulation of JNK cascade, positive regulation of protein kin...
Does Knockout of Spata17 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Spata17
cell proliferation
Mouse kidney carcinoma cell
Gene: Spata17 (spermatogenesis associated 17) Type: protein-coding Summary: Predicted to enable calmodulin binding activity. Predicted to be located in cytoplasm. Orthologous to human SPATA17 (spermatogenesis associated 17). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: MF...
Does Knockout of Zfp618 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Zfp618
cell proliferation
Melanoma Cell Line
Gene: Zfp618 (zinc finger protein 618) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, chromatin-protein adaptor activity, identical protein binding, metal ion binding, transcription coregulator binding, zinc ion binding; CC: chromatin, chromosome, nucleus, p...
Does Knockout of Ppp2ca in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ppp2ca
cell proliferation
Embryonic Stem Cell Line
Gene: Ppp2ca (protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II transcription initiation surveillance, T cell homeostasis, meiotic cell cycle, mesoderm development, mitotic cell cycle, ...
Does Knockout of Smyd1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Smyd1
cell proliferation
Mouse kidney carcinoma cell
Gene: Smyd1 (SET and MYND domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin remodeling, heart development, methylation, negative regulation of DNA-templated transcription, positive regulation of myoblast differentiation, positive regulation of...
Does Knockout of B2m in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
B2m
cell proliferation
Colonic Cancer Cell Line
Gene: B2m (beta-2 microglobulin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell differentiation in thymus, amyloid fibril formation, antibacterial humoral response, antigen processing and presentation of endogenous peptide antigen via MHC class I, antigen processi...
Does Knockout of 1700020A23Rik in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
1700020A23Rik
cell proliferation
Colonic Cancer Cell Line
Gene: 1700020A23Rik (RIKEN cDNA 1700020A23 gene) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q9DA59 Entrez ID: 75656
Does Knockout of Amigo1 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Amigo1
protein/peptide distribution
myoblast cell line
Gene: Amigo1 (adhesion molecule with Ig like domain 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axonal fasciculation, axonogenesis, brain development, cell adhesion, cell differentiation, cellular response to L-glutamate, heterophilic cell-cell adhesion via plasma ...
Does Knockout of Pcdh1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Pcdh1
autophagy
Embryonic Fibroblast Cell Line
Gene: Pcdh1 (protocadherin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell ad...
Does Knockout of Kif18b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Kif18b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Kif18b (kinesin family member 18B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, microtubule depolymerization, microtubule-based movement, mitotic cell cycle, mitotic sister chromatid segregation, regulation of cell division; MF: ATP binding, ATP hy...
Does Knockout of Bsn in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Bsn
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Bsn (bassoon) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axo-dendritic transport, maintenance of presynaptic active zone structure, modulation of chemical synaptic transmission, presynaptic active zone assembly, presynaptic active zone organization, protein loc...
Does Knockout of Vmn1r216 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Vmn1r216
cell proliferation
Mouse kidney carcinoma cell
Gene: Vmn1r216 (vomeronasal 1 receptor 216) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8R257 Entrez ID: 171279
Does Knockout of Ubtf in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Ubtf
cell proliferation
Embryonic Stem Cell Line
Gene: Ubtf (upstream binding transcription factor, RNA polymerase I) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase I preinitiation complex assembly, cellular response to leukemia inhibitory factor, positive regulation of transcription by RNA polymerase I,...
Does Knockout of Ppp1r14d in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Ppp1r14d
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ppp1r14d (protein phosphatase 1, regulatory inhibitor subunit 14D) Type: protein-coding Summary: No summary available. Gene Ontology: MF: protein phosphatase inhibitor activity, protein serine/threonine phosphatase inhibitor activity; CC: cellular_component, cytoplasm Pathways: ...
Does Knockout of A830035O19Rik in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
A830035O19Rik
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: A830035O19Rik (RIKEN cDNA A830035O19 gene) Type: ncRNA Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 100101457
Does Knockout of D930020B18Rik in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
D930020B18Rik
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: D930020B18Rik (RIKEN cDNA D930020B18 gene) Type: protein-coding Summary: Is expressed in epididymis; olfactory epithelium; and vomeronasal organ. Orthologous to human C12orf56 (chromosome 12 open reading frame 56). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: ...
Does Knockout of Gar1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Gar1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Gar1 (GAR1 ribonucleoprotein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: pseudouridine synthesis, rRNA processing, ribosome biogenesis, snoRNA guided rRNA pseudouridine synthesis, telomere maintenance via telomerase; MF: RNA binding, box H/ACA snoRNA binding, p...
Does Knockout of Zfp566 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Zfp566
protein/peptide distribution
myoblast cell line
Gene: Zfp566 (zinc finger protein 566) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Phf5a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Phf5a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Phf5a (PHD finger protein 5A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome, positive regulation of DNA-templated transcription, stem cell differentiation; MF: DNA binding, RNA binding, metal ion bindin...
Does Knockout of Stat2 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Stat2
cell proliferation
Mouse kidney carcinoma cell
Gene: Stat2 (signal transducer and activator of transcription 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway via JAK-STAT, defense response, defense response to virus, negative regulation of type I interferon-mediated signaling ...
Does Knockout of Fdxr in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Fdxr
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Fdxr (ferredoxin reductase) Type: protein-coding Summary: Predicted to enable NADPH binding activity and ferredoxin-NADP+ reductase activity. Predicted to be involved in steroid biosynthetic process. Located in mitochondrial inner membrane. Orthologous to human FDXR (ferredoxin reductase). [provid...
Does Knockout of Rit2 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Rit2
autophagy
Embryonic Fibroblast Cell Line
Gene: Rit2 (Ras-like without CAAX 2) Type: protein-coding Summary: Enables several functions, including GTP binding activity; GTPase activity; and calmodulin binding activity. Involved in several processes, including Ras protein signal transduction; regulation of Cdc42 protein signal transduction; and r...
Does Knockout of Grik4 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Grik4
response to virus
Embryonic Fibroblast Cell Line
Gene: Grik4 (glutamate receptor, ionotropic, kainate 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ionotropic glutamate receptor signaling pathway, modulation of chemical synaptic transmission, monoatomic ion transmembrane transport, monoatomic ion transport, regulat...
Does Knockout of Nrbp1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Nrbp1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nrbp1 (nuclear receptor binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endoplasmic reticulum to Golgi vesicle-mediated transport, epithelial cell differentiation, epithelial cell proliferation, in utero embryonic development, intracellular signal...
Does Knockout of Cdhr5 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Cdhr5
protein/peptide distribution
myoblast cell line
Gene: Cdhr5 (cadherin-related family member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brush border assembly, cell adhesion, cell differentiation, cell-cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules, intermicrovillar adhesion, regul...
Does Knockout of Prl2a1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Prl2a1
cell proliferation
Embryonic Stem Cell Line
Gene: Prl2a1 (prolactin family 2, subfamily a, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway, female pregnancy, mammary gland development, positive regulation of lactation, positive regulation of receptor signaling pathw...
Does Knockout of Fkbp2 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Fkbp2
protein/peptide distribution
myoblast cell line
Gene: Fkbp2 (FK506 binding protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: isomerase activity, peptidyl-prolyl cis-trans isomerase activity; CC: endoplasmic reticulum, endoplasmic reticulum membrane, membrane Pathways: UniProt: P45878 ...
Does Knockout of Luc7l3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Luc7l3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Luc7l3 (LUC7-like 3 (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splice site recognition; MF: DNA binding, mRNA binding; CC: U1 snRNP, U2-type prespliceosome, nuclear speck, nucleoplasm, nucleus Pathwa...
Does Knockout of Cdk4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Cdk4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cdk4 (cyclin dependent kinase 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G1/S transition of mitotic cell cycle, cell division, cellular response to interleukin-4, cellular response to ionomycin, cellular response to lipopolysaccharide, cellular response to p...
Does Knockout of A930003A15Rik in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
A930003A15Rik
cell proliferation
Colonic Cancer Cell Line
Gene: A930003A15Rik (RIKEN cDNA A930003A15 gene) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Dnlz in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Dnlz
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dnlz (DNL-type zinc finger) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chaperone-mediated protein complex assembly, protein folding, protein import into mitochondrial matrix, protein stabilization; MF: metal ion binding, protein folding chaperone, protein-foldi...
Does Knockout of Ptger4 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Ptger4
cell proliferation
Mouse kidney carcinoma cell
Gene: Ptger4 (prostaglandin E receptor 4 (subtype EP4)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERK1 and ERK2 cascade, G protein-coupled receptor signaling pathway, JNK cascade, MAPK cascade, T-helper cell differentiation, adenylate cyclase-activating G protein-co...
Does Knockout of Hoxb9 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Hoxb9
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Hoxb9 (homeobox B9) Type: protein-coding Summary: Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic skeletal system development; mammary gland development; and positive regulati...
Does Knockout of Zcchc18 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Zcchc18
phagocytosis
macrophage
Gene: Zcchc18 (zinc finger, CCHC domain containing 18) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, zinc ion binding Pathways: UniProt: Q8VD24 Entrez ID: 66995
Does Knockout of Gpr152 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Gpr152
protein/peptide distribution
myoblast cell line
Gene: Gpr152 (G protein-coupled receptor 152) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity, identical protein binding; CC: membrane, plasma membrane Path...
Does Knockout of Lrtm1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Lrtm1
protein/peptide distribution
myoblast cell line
Gene: Lrtm1 (leucine-rich repeats and transmembrane domains 1) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8BXQ3 Entrez ID: 319476
Does Knockout of Rpl34 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Rpl34
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rpl34 (ribosomal protein L34) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: structural constituent of ribosome; CC: cytoplasm, cytosol, cytosolic large ribosomal subun...
Does Knockout of Flcn in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Flcn
cell proliferation
Embryonic Stem Cell Line
Gene: Flcn (folliculin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, TORC1 signaling, cell-cell junction assembly, cellular response to amino acid starvation, cellular response to nutrient levels,...