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Does Knockout of Clip2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Clip2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Clip2 (CAP-GLY domain containing linker protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: microtubule binding, microtubule plus-end binding, protein binding; CC: cell cortex, cytoplasm, cytoplasmic microtubule, cytoskeleton, dendritic microtubule, lamellar ...
Does Knockout of Mterf2 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Mterf2
cell proliferation
Embryonic Stem Cell Line
Gene: Mterf2 (mitochondrial transcription termination factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, nucleic acid binding; CC: mitochondrial matrix, mitochondrial nucleoid, mitochondrion Pathways: UniProt: Q8BKY8 Entrez I...
Does Knockout of Pik3c3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Pik3c3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pik3c3 (phosphatidylinositol 3-kinase catalytic subunit type 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, autophagosome maturation, autophagy, cell division, cellular response to glucose starvation, cellular response to starvation, earl...
Does Knockout of Lap3 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Lap3
protein/peptide distribution
myoblast cell line
Gene: Lap3 (leucine aminopeptidase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteolysis; MF: aminopeptidase activity, carboxypeptidase activity, hydrolase activity, manganese ion binding, metal ion binding, metalloaminopeptidase activity, peptidase activity; CC:...
Does Knockout of Med24 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Med24
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Med24 (mediator complex subunit 24) Type: protein-coding Summary: This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited b...
Does Knockout of AA986860 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
AA986860
protein/peptide distribution
Microglial Cell Line
Gene: AA986860 (expressed sequence AA986860) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, cytosol, plasma membrane Pathways: UniProt: Q8BI29 Entrez ID: 212439
Does Knockout of Ttll5 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Ttll5
autophagy
Embryonic Fibroblast Cell Line
Gene: Ttll5 (tubulin tyrosine ligase-like family, member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fertilization, flagellated sperm motility, retina development in camera-type eye, sperm axoneme assembly, spermatogenesis; MF: ATP binding, ligase activity, metal i...
Does Knockout of Rabif in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Rabif
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rabif (RAB interacting factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: post-Golgi vesicle-mediated transport, protein transport, small GTPase-mediated signal transduction; MF: guanyl-nucleotide exchange factor activity, metal ion binding, zinc ion binding; C...
Does Knockout of Lbp in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Lbp
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Lbp (lipopolysaccharide binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acute-phase response, cell surface pattern recognition receptor signaling pathway, cellular response to lipopolysaccharide, cellular response to lipoteichoic acid, defense respo...
Does Knockout of Tmie in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Tmie
protein/peptide accumulation
Embryonic Cell Line
Gene: Tmie (transmembrane inner ear) Type: protein-coding Summary: No summary available. Gene Ontology: BP: inner ear morphogenesis, sensory perception of sound; CC: membrane, plasma membrane Pathways: UniProt: Q8K467 Entrez ID: 20776
Does Knockout of Vps18 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
1,130
Knockout
Vps18
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Vps18 (VPS18 CORVET/HOPS core subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagy, endosome organization, endosome to lysosome transport, intracellular protein transport, lysosome organization, negative regulation of intracellular estrogen receptor si...
Does Knockout of Prepl in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Prepl
protein/peptide distribution
myoblast cell line
Gene: Prepl (prolyl endopeptidase-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to plasma membrane protein transport, proteolysis, regulation of synaptic vesicle exocytosis, retrograde transport, endosome to Golgi; MF: hydrolase activity, peptidase activity,...
Does Knockout of Arg1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Arg1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Arg1 (arginase, liver) Type: protein-coding Summary: Enables arginase activity. Involved in defense response to protozoan; negative regulation of T-helper 2 cell cytokine production; and negative regulation of activated T cell proliferation. Acts upstream of or within response to nematode. Predict...
Does Knockout of Aars2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Aars2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Aars2 (alanyl-tRNA synthetase 2, mitochondrial) Type: protein-coding Summary: No summary available. Gene Ontology: BP: alanyl-tRNA aminoacylation, aminoacyl-tRNA metabolism involved in translational fidelity, cGAS/STING signaling pathway, mitochondrial alanyl-tRNA aminoacylation, negative...
Does Knockout of Jak2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation?
1
2,141
Knockout
Jak2
cell proliferation
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Jak2 (Janus kinase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T-helper 1 cell differentiation, activation of Janus kinase activity, adaptive immune response, apoptotic signaling pathway, axon regeneration, cell adhesion, cell differentiation, cell surface re...
Does Knockout of Rps26 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Rps26
cell proliferation
Melanoma Cell Line
Gene: Rps26 (ribosomal protein S26) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, negative regulation of RNA splicing, translation, translation at postsynapse, translation at presynapse; MF: mRNA binding, structural constituent of ribosome; CC: ...
Does Knockout of Spata1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Spata1
autophagy
Embryonic Fibroblast Cell Line
Gene: Spata1 (spermatogenesis associated 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: molecular_function, protein binding; CC: acrosomal vesicle, cytoplasmic vesicle Pathways: UniProt: Q9D5R4 Entrez ID: 70951
Does Knockout of Wfdc16 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Wfdc16
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Wfdc16 (WAP four-disulfide core domain 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, innate immune response; MF: peptidase inhibitor activity, serine-type endopeptidase inhibitor activity; CC: extracellular region, extracellular...
Does Knockout of Sema3e in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Sema3e
cell proliferation
Melanoma Cell Line
Gene: Sema3e (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, axon guidance, branching involved in blood vessel morphogenesis, cell differentiation, gonadotrophin-releasi...
Does Knockout of Sh3tc1 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Sh3tc1
protein/peptide distribution
myoblast cell line
Gene: Sh3tc1 (SH3 domain and tetratricopeptide repeats 1) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q3TXV8, G3X9F6, Q3UDI4, F6QD49, F6UWL1, F6U4F1 Entrez ID: 231147
Does Knockout of Nr1h4 in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
1
1,522
Knockout
Nr1h4
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Nr1h4 (nuclear receptor subfamily 1, group H, member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, bile acid metabolic process, cell differentiation, cell-cell junction assembly, cellular response to bile acid, cellular response to fatt...
Does Knockout of Taf1d in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Taf1d
cell proliferation
Embryonic Stem Cell Line
Gene: Taf1d (TATA-box binding protein associated factor, RNA polymerase I, D) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, regulation of DNA-templated transcription; MF: DNA binding, identical protein binding, molecular_function; CC: RNA polymerase ...
Does Knockout of Mrpl32 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Mrpl32
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Mrpl32 (mitochondrial ribosomal protein L32) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: metal ion binding, structural constituent of ribosome; CC: cytosol, large ribosomal subunit, mitochondrial inner membrane, mitoch...
Does Knockout of Rpl7a in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Rpl7a
cell proliferation
Mouse kidney carcinoma cell
Gene: Rpl7a (ribosomal protein L7A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, maturation of LSU-rRNA, ribosome biogenesis, translation at postsynapse, translation at presynapse; MF: RNA binding, protein binding, structural constituent of rib...
Does Knockout of Aimp1 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Aimp1
protein/peptide distribution
myoblast cell line
Gene: Aimp1 (aminoacyl tRNA synthetase complex-interacting multifunctional protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, apoptotic process, cell-cell signaling, inflammatory response, leukocyte migration, negative regulation of endothelial cell ...
Does Knockout of Tmem82 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Tmem82
protein/peptide distribution
myoblast cell line
Gene: Tmem82 (transmembrane protein 82) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q8R115 Entrez ID: 213989
Does Knockout of Eloc in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Eloc
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Eloc (elongin C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of transcription elongation by RNA polymerase II, protein ubiquitination, target-directed miRNA degradation, transcription initiation at RNA polymerase II promoter, ubiquitin-depend...
Does Knockout of BC107364 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
BC107364
cell proliferation
Embryonic Stem Cell Line
Gene: BC107364 (cDNA sequence BC107364) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q3KNB6 Entrez ID: 329716
Does Knockout of Eif2s1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Eif2s1
cell proliferation
Embryonic Stem Cell Line
Gene: Eif2s1 (eukaryotic translation initiation factor 2, subunit 1 alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: HRI-mediated signaling, PERK-mediated unfolded protein response, cellular response to UV, cellular response to amino acid starvation, cellular respon...
Does Knockout of Tex9 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Tex9
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Tex9 (testis expressed gene 9) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, centriolar satellite, cytoplasm, cytoskeleton Pathways: UniProt: Q9D845 Entrez ID: 21778
Does Knockout of Defb15 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Defb15
protein/peptide accumulation
Embryonic Cell Line
Gene: Defb15 (defensin beta 15) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response, defense response to bacterium, innate immune response; MF: CCR2 chemokine receptor binding, heparin binding, lipopolysaccharide binding; CC: extracellular region, membrane, m...
Does Knockout of Vmn1r107 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Vmn1r107
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Vmn1r107 (vomeronasal 1 receptor 107) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled recepto...
Does Knockout of Nol9 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Nol9
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nol9 (nucleolar protein 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA processing, cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of 5.8S rRNA, rRNA processing; MF: ATP binding, ATP...
Does Knockout of Tmem154 in Regulatory T cell causally result in protein/peptide accumulation?
1
1,482
Knockout
Tmem154
protein/peptide accumulation
Regulatory T cell
Gene: Tmem154 (transmembrane protein 154) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q8C4Q9 Entrez ID: 320782
Does Knockout of Ptpa in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Ptpa
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ptpa (protein phosphatase 2 protein activator) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitotic spindle organization, positive regulation of apoptotic process; MF: ATP binding, isomerase activity, metal ion binding, nucleotide binding, peptidyl-prolyl cis-tra...
Does Knockout of Yme1l1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Yme1l1
cell proliferation
Embryonic Stem Cell Line
Gene: Yme1l1 (YME1-like 1 (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell population proliferation, cellular response to starvation, mitochondrial protein catabolic process, mitochondrial protein processing, mitochondrion organization, negative regul...
Does Knockout of Hspa13 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,440
Knockout
Hspa13
protein/peptide accumulation
Embryonic Cell Line
Gene: Hspa13 (heat shock protein 70 family, member 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein folding, protein refolding; MF: ATP binding, ATP hydrolysis activity, ATP-dependent protein folding chaperone, heat shock protein binding, nucleotide binding, pr...
Does Knockout of Car5a in macrophage causally result in phagocytosis?
0
1,888
Knockout
Car5a
phagocytosis
macrophage
Gene: Car5a (carbonic anhydrase 5a, mitochondrial) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carbonate dehydratase activity, lyase activity, metal ion binding, zinc ion binding; CC: cytoplasm, mitochondrion Pathways: Metabolism, Nitrogen metabolism - Mus mu...
Does Knockout of Ube2n in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation?
1
2,142
Knockout
Ube2n
cell proliferation
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ube2n (ubiquitin-conjugating enzyme E2N) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA double-strand break processing, DNA repair, T cell receptor signaling pathway, TORC1 signaling, antiviral innate immune response, cellular response to n...
Does Knockout of Tsen54 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Tsen54
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tsen54 (tRNA splicing endonuclease subunit 54) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA processing, tRNA processing, tRNA splicing, via endonucleolytic cleavage and ligation, tRNA-type intron splice site recognition and cleavage; CC: nucleolus, nucleus, ...
Does Knockout of Hs6st3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Hs6st3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Hs6st3 (heparan sulfate 6-O-sulfotransferase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: heparan sulfate proteoglycan biosynthetic process; MF: heparan sulfate 6-sulfotransferase activity, sulfotransferase activity, transferase activity; CC: Golgi apparatus, ...
Does Knockout of Ppan in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Ppan
cell proliferation
Embryonic Stem Cell Line
Gene: Ppan (peter pan homolog) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA processing, regulation of cell growth by extracellular stimulus; MF: rRNA binding; CC: nucleolus, ...
Does Knockout of Heyl in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Heyl
protein/peptide distribution
Microglial Cell Line
Gene: Heyl (hairy/enhancer-of-split related with YRPW motif-like) Type: protein-coding Summary: Enables DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein homodimerization activity. Involved i...
Does Knockout of Brf1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Brf1
cell proliferation
Embryonic Stem Cell Line
Gene: Brf1 (BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription initiation, positive regulation of transcription by RNA polymerase III, regulation of mRNA stability, transcrip...
Does Knockout of Suds3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Suds3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Suds3 (suppressor of defective silencing 3 homolog (S. cerevisiae)) Type: protein-coding Summary: Enables histone deacetylase binding activity and identical protein binding activity. Involved in negative regulation of DNA-templated transcription. Acts upstream of or within blastocyst hatching. Par...
Does Knockout of Inca1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Inca1
cell proliferation
Embryonic Stem Cell Line
Gene: Inca1 (inhibitor of CDK, cyclin A1 interacting protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic signaling pathway, negative regulation of cell population proliferation, negative regulation of fibroblast proliferation, positive regulation of apopt...
Does Knockout of Prrt3 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Prrt3
protein/peptide accumulation
Mouse cell
Gene: Prrt3 (proline-rich transmembrane protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q6PE13 Entrez ID: 210673
Does Knockout of Cntd1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Cntd1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cntd1 (cyclin N-terminal domain containing 1) Type: protein-coding Summary: Involved in regulation of meiotic cell cycle. Acts upstream of or within reciprocal meiotic recombination and spermatogenesis. Located in chromosome. Orthologous to human CNTD1 (cyclin N-terminal domain containing 1). [pro...
Does Knockout of Unc13c in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Unc13c
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Unc13c (unc-13 homolog C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chemical synaptic transmission, dense core granule priming, exocytosis, modulation of chemical synaptic transmission, negative regulation of synaptic plasticity, synaptic transmission, glutama...
Does Knockout of Nxf3 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Nxf3
cell proliferation
Embryonic Stem Cell Line
Gene: Nxf3 (nuclear RNA export factor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA export from nucleus, mRNA transport, poly(A)+ mRNA export from nucleus, protein transport; MF: RNA binding, mRNA binding, nucleic acid binding, protein binding; CC: cytoplasm, cy...
Does Knockout of Lcn9 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Lcn9
protein/peptide distribution
myoblast cell line
Gene: Lcn9 (lipocalin 9) Type: protein-coding Summary: No summary available. Gene Ontology: MF: molecular_function, small molecule binding; CC: extracellular region, extracellular space Pathways: SLC-mediated transmembrane transport, Transport of fatty acids, Transport of small molecul...
Does Knockout of Anln in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Anln
cell proliferation
Mouse kidney carcinoma cell
Gene: Anln (anillin, actin binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actomyosin contractile ring assembly, cell division, hematopoietic progenitor cell differentiation, mitotic cytokinesis, podocyte cell migration, positive regulation of bleb assemb...
Does Knockout of Pdap1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Pdap1
cell proliferation
Mouse kidney carcinoma cell
Gene: Pdap1 (PDGFA associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytosol, extracellular space, plasma membrane Pathways: Immune System, Innate Immune System, Neutrophil degranulation UniProt: Q3UHX2 Entrez ID: 231887
Does Knockout of Zzz3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Zzz3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Zzz3 (zinc finger, ZZ domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, regulation of DNA-templated transcription, regulation of cell cycle, regulation of cell division, regulation of embryonic development, regulation of tr...
Does Knockout of Gltp in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Gltp
cell cycle progression
breast epithelium
Gene: Gltp (glycolipid transfer protein) Type: protein-coding Summary: Predicted to enable several functions, including ceramide 1-phosphate binding activity; ceramide 1-phosphate transfer activity; and identical protein binding activity. Predicted to be involved in ceramide transport and intermembrane ...
Does Knockout of Ppp6r2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Ppp6r2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ppp6r2 (protein phosphatase 6, regulatory subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: protein phosphatase binding, protein phosphatase regulator activity; CC: cytoplasm, cytoplasmic ribonucleoprotein granule, cytosol, nucleus Pathways: ...
Does Knockout of Pcdhgb2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Pcdhgb2
cell proliferation
Colonic Cancer Cell Line
Gene: Pcdhgb2 (protocadherin gamma subfamily B, 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding, metal ion binding, protein binding; ...
Does Knockout of Gm9755 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Gm9755
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Gm9755 (Tu translation elongation factor pseudogene) Type: pseudo Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 100041265
Does Knockout of H2-Eb1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
H2-Eb1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: H2-Eb1 (histocompatibility 2, class II antigen E beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processin...
Does Knockout of Tbcel in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Tbcel
protein/peptide distribution
myoblast cell line
Gene: Tbcel (tubulin folding cofactor E-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule cytoskeleton organization, post-chaperonin tubulin folding pathway, tubulin complex assembly; CC: cytoplasm, cytoskeleton Pathways: UniProt: Q8C5W3...
Does Knockout of Keap1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Keap1
cell proliferation
Colonic Cancer Cell Line
Gene: Keap1 (kelch-like ECH-associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to carbohydrate stimulus, cellular response to interleukin-4, cellular response to oxidative stress, in utero embryonic development, negative regulation of ...
Does Knockout of Clec4a3 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Clec4a3
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Clec4a3 (C-type lectin domain family 4, member a3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CD8-positive, alpha-beta T cell activation, adaptive immune response, antifungal innate immune response, antigen processing and presentation of exogenous peptide antig...
Does Knockout of Arl13b in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Arl13b
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Arl13b (ADP-ribosylation factor-like 13B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cilium assembly, determination of left/right symmetry, dorsal/ventral pattern formation, formation of radial glial scaffolds, heart looping, interneuron migration from the subp...
Does Knockout of Sgo1 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Sgo1
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Sgo1 (shugoshin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: attachment of spindle microtubules to kinetochore, cell division, centriole-centriole cohesion, chromosome segregation, meiotic chromosome segregation, mitotic sister chromatid cohesion, centromeric;...
Does Knockout of Qrsl1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Qrsl1
cell proliferation
Colonic Cancer Cell Line
Gene: Qrsl1 (glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation, regulation of protein stability, translation; MF: ATP binding, carbon-nitro...
Does Knockout of Dsn1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Dsn1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Dsn1 (DSN1 homolog, MIS12 kinetochore complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: attachment of spindle microtubules to kinetochore, cell division, chromosome segregation, skeletal muscle satellite cell proliferation; CC: MIS12/MIND type compl...
Does Knockout of Chchd5 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Chchd5
cell proliferation
Embryonic Stem Cell Line
Gene: Chchd5 (coiled-coil-helix-coiled-coil-helix domain containing 5) Type: protein-coding Summary: No summary available. Gene Ontology: CC: mitochondrial intermembrane space, mitochondrion Pathways: UniProt: Q9CQP3 Entrez ID: 66170
Does Knockout of Hspa9 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Hspa9
cell proliferation
Embryonic Stem Cell Line
Gene: Hspa9 (heat shock protein 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium import into the mitochondrion, erythrocyte differentiation, iron-sulfur cluster assembly, negative regulation of erythrocyte differentiation, negative regulation of hematopoietic st...
Does Knockout of Ptchd4 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Ptchd4
phagocytosis
macrophage
Gene: Ptchd4 (patched domain containing 4) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane Pathways: UniProt: B9EKX1 Entrez ID: 627626
Does Knockout of Fh1 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Fh1
protein/peptide distribution
myoblast cell line
Gene: Fh1 (fumarate hydratase 1) Type: protein-coding Summary: Enables fumarate hydratase activity. Involved in several processes, including carboxylic acid metabolic process; positive regulation of cold-induced thermogenesis; and tricarboxylic acid cycle. Acts upstream of or within homeostasis of numbe...
Does Knockout of Gm6083 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Gm6083
cell proliferation
Melanoma Cell Line
Gene: Gm6083 (predicted gene 6083) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Ddx41 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Ddx41
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ddx41 (DEAD box helicase 41) Type: protein-coding Summary: Enables DNA binding activity. Acts upstream of or within cellular response to interferon-beta; defense response to virus; and positive regulation of transcription by RNA polymerase II. Located in endoplasmic reticulum and nucleus. Is expre...
Does Knockout of Stk10 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Stk10
cell proliferation
Regulatory T cell
Gene: Stk10 (serine/threonine kinase 10) Type: protein-coding Summary: This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. Mice deficient for this gene product are viable, but exhibit altered integrin-mediated lymp...
Does Knockout of Tpte in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Tpte
protein/peptide accumulation
Embryonic Cell Line
Gene: Tpte (transmembrane phosphatase with tensin homology) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport, phosphate-containing compound metabolic process, transmembrane transport; MF: hydrolase activity, ...
Does Knockout of Immp1l in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Immp1l
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Immp1l (IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein processing involved in protein targeting to mitochondrion, proteolysis, signal peptide processing; MF: hydrolase activity, peptidase act...
Does Knockout of Rpsa in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Rpsa
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rpsa (ribosomal protein SA) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cytoplasmic translation, ribosomal small subunit assembly, translation; MF: DNA binding, laminin binding, laminin receptor activity, protein binding, ribosome binding, structu...
Does Knockout of Adam12 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Adam12
protein/peptide distribution
myoblast cell line
Gene: Adam12 (ADAM metallopeptidase domain 12) Type: protein-coding Summary: This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded preproprotei...
Does Knockout of Eef2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Eef2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Eef2 (eukaryotic translation elongation factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to brain-derived neurotrophic factor stimulus, glial cell proliferation, hematopoietic progenitor cell differentiation, positive regulation of cytopla...
Does Knockout of Ankrd42 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Ankrd42
response to virus
Microglial Cell Line
Gene: Ankrd42 (ankyrin repeat domain 42) Type: protein-coding Summary: No summary available. Gene Ontology: MF: NF-kappaB binding, cyclin-dependent protein serine/threonine kinase inhibitor activity, protein binding; CC: nucleus Pathways: UniProt: Q3V096 Entrez ID: 73...
Does Knockout of Nae1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Nae1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nae1 (NEDD8 activating enzyme E1 subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, mitotic DNA replication checkpoint signaling, neuron apoptotic process, protein neddylation, regulation of apoptotic process, regulation of neuron apoptoti...
Does Knockout of Med15 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Med15
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Med15 (mediator complex subunit 15) Type: protein-coding Summary: Predicted to enable transcription coregulator activity. Acts upstream of or within somatic stem cell population maintenance. Predicted to be located in nucleoplasm. Predicted to be part of core mediator complex. Is expressed in seve...
Does Knockout of Banf1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Banf1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Banf1 (BAF nuclear assembly factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA integration, DNA repair, cGAS/STING signaling pathway, chromatin organization, chromosome organization, establishment of integrated proviral latency, mitotic nuclear membrane r...
Does Knockout of Casr in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Casr
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Casr (calcium-sensing receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, JNK cascade, adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, bile acid secretion, branching morphogenesis of an e...
Does Knockout of Slc25a26 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Slc25a26
cell proliferation
Embryonic Stem Cell Line
Gene: Slc25a26 (solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-alpha-amino acid transmembrane transport, S-adenosyl-L-methionine transport, mitochondrial S-adenosyl-L-methionine transmembra...
Does Knockout of Fis1 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Fis1
cell viability
Immortal mouse chromaffin cells
Gene: Fis1 (fission, mitochondrial 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cellular response to peptide, mitochondrial fission, mitochondrial fragmentation involved in apoptotic process, mitochondrion organization, negative regulation of ATP ...
Does Knockout of Col11a2 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Col11a2
protein/peptide distribution
myoblast cell line
Gene: Col11a2 (collagen, type XI, alpha 2) Type: protein-coding Summary: This gene encodes the alpha-2 subunit of type XI collagen, one of the low abundance fibrillar collagens found in cartilage. The encoded protein, in association with other collagen subunits, forms a heterotrimeric type XI procollage...
Does Knockout of Grk1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Grk1
protein/peptide distribution
myoblast cell line
Gene: Grk1 (G protein-coupled receptor kinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of neuron apoptotic process, photoreceptor cell morphogenesis, positive regulation of phosphorylation, post-embryonic retina morphogenesis in camera-type e...
Does Knockout of Vmn1r135 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Vmn1r135
cell viability
Immortal mouse chromaffin cells
Gene: Vmn1r135 (vomeronasal 1 receptor 135) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled recepto...
Does Knockout of Sntg2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Sntg2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Sntg2 (syntrophin, gamma 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: PDZ domain binding, actin binding, neuroligin family protein binding, protein binding, structural molecule activity; CC: cytoplasm, cytoskeleton, dystrophin-associated glycoprotein complex, ...
Does Knockout of Slc14a2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Slc14a2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Slc14a2 (solute carrier family 14 (urea transporter), member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: urea transmembrane transport, urea transport; MF: cell adhesion molecule binding, urea transmembrane transporter activity; CC: apical plasma membrane, bas...
Does Knockout of D030056L22Rik in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
D030056L22Rik
protein/peptide distribution
myoblast cell line
Gene: D030056L22Rik (RIKEN cDNA D030056L22 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8VCE4 Entrez ID: 225995
Does Knockout of Adgrl3 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Adgrl3
protein/peptide distribution
myoblast cell line
Gene: Adgrl3 (adhesion G protein-coupled receptor L3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, Rho-activating G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signali...
Does Knockout of Prrg2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Prrg2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Prrg2 (proline-rich Gla (G-carboxyglutamic acid) polypeptide 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, blood coagulation, proteolysis; MF: calcium ion binding, protein binding, serine-type endopeptidase activity; CC: extracellular region...
Does Knockout of Nek11 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Nek11
cell cycle progression
breast epithelium
Gene: Nek11 (NIMA (never in mitosis gene a)-related expressed kinase 11) Type: protein-coding Summary: Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in mitotic intra-S DNA damage checkpoint signaling; protein phosphorylation; and regulati...
Does Knockout of Glo1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Glo1
protein/peptide accumulation
Embryonic Cell Line
Gene: Glo1 (glyoxalase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glutathione metabolic process, methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione, methylglyoxal metabolic process, negative regulation of apoptotic process, osteoclast different...
Does Knockout of Magea10 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Magea10
response to virus
Microglial Cell Line
Gene: Magea10 (MAGE family member A10) Type: protein-coding Summary: Predicted to enable DNA-binding transcription factor binding activity; histone deacetylase binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in negative regulation of transcription by RNA polymer...
Does Knockout of Has2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Has2
cell proliferation
Colonic Cancer Cell Line
Gene: Has2 (hyaluronan synthase 2) Type: protein-coding Summary: Enables hyaluronan synthase activity. Involved in several processes, including circulatory system development; extracellular matrix assembly; and hyaluronan biosynthetic process. Acts upstream of or within bone morphogenesis and hyaluronan...
Does Knockout of Zfp628 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Zfp628
protein/peptide accumulation
Regulatory T cell
Gene: Zfp628 (zinc finger protein 628) Type: protein-coding Summary: No summary available. Gene Ontology: BP: developmental process, positive regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II, spermatoge...
Does Knockout of Foxj1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Foxj1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Foxj1 (forkhead box J1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, axoneme assembly, brain development, cell maturation, cell projection organization, central tolerance induction, ciliary basal body organization, cilium assembly...
Does Knockout of Rtn4rl1 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Rtn4rl1
protein/peptide distribution
myoblast cell line
Gene: Rtn4rl1 (reticulon 4 receptor-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon guidance, corpus callosum development, negative chemotaxis, negative regulation of axon regeneration, negative regulation of neuron projection development; MF: Roundabout bind...