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Does Knockout of Fpr-rs6 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Fpr-rs6
cell proliferation
Mouse kidney carcinoma cell
Gene: Fpr-rs6 (formyl peptide receptor, related sequence 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, complement receptor mediated signaling pathway, inflammatory response, phospholipase C-activating G protein-coupled re...
Does Knockout of Rictor in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Rictor
cell proliferation
Embryonic Stem Cell Line
Gene: Rictor (RPTOR independent companion of MTOR, complex 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: TOR signaling, TORC2 signaling, actin cytoskeleton organization, cGAS/STING signaling pathway, cellular response to nutrient levels, cytoskeleton organization, em...
Does Knockout of Ndufs8 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Ndufs8
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ndufs8 (NADH:ubiquinone oxidoreductase core subunit S8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, mitochondrial electron transport, NADH to ubiquinone, mitochondrial respiratory chain complex I assembly, proton motive force-driven mitochon...
Does Knockout of Syt17 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Syt17
cell proliferation
Embryonic Stem Cell Line
Gene: Syt17 (synaptotagmin XVII) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, positive regulation of dendrite extension, regulation of calcium ion-dependent exocytosis, regulation of postsynaptic neurotransmitter receptor internalization, vesicle-...
Does Knockout of Vps36 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Vps36
protein/peptide accumulation
Embryonic Cell Line
Gene: Vps36 (vacuolar protein sorting 36) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endosomal transport, endosome transport via multivesicular body sorting pathway, protein transport, protein transport to vacuole involved in ubiquitin-dependent protein catabolic pro...
Does Knockout of Rfpl4b in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Rfpl4b
cell proliferation
Embryonic Stem Cell Line
Gene: Rfpl4b (ret finger protein-like 4B) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, zinc ion binding Pathways: UniProt: J3QPR6 Entrez ID: 215919
Does Knockout of Nuak1 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Nuak1
protein/peptide distribution
myoblast cell line
Gene: Nuak1 (NUAK family, SNF1-like kinase, 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, cell adhesion, protein phosphorylation, regulation of cell adhesion, regulation of cellular senescence; MF: ATP binding, kinase activity, nucleotide binding...
Does Knockout of Tecr in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
1
1,522
Knockout
Tecr
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Tecr (trans-2,3-enoyl-CoA reductase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid biosynthetic process, fatty acid elongation, fatty acid metabolic process, lipid metabolic process, sphingolipid metabolic process, steroid biosynthetic process, very lon...
Does Knockout of Rab5c in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Rab5c
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rab5c (RAB5C, member RAS oncogene family) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endocytosis, endosomal transport, endosome organization, intracellular protein transport, plasma membrane to endosome transport, protein transport, regulation of endocytosis; M...
Does Knockout of Mpv17l2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Mpv17l2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mpv17l2 (MPV17 mitochondrial membrane protein-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial ribosome assembly, positive regulation of mitochondrial translation; MF: mitochondrial large ribosomal subunit binding, molecular_function; CC: cytopl...
Does Knockout of Rbm12 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Rbm12
protein/peptide distribution
myoblast cell line
Gene: Rbm12 (RNA binding motif protein 12) Type: protein-coding Summary: This gene encodes a protein that contains several RNA-binding motifs, potential transmembrane domains, and proline-rich regions. This gene and the gene for copine I overlap at map location 2 H2. Two alternatively spliced transcript...
Does Knockout of Sfxn1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Sfxn1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sfxn1 (sideroflexin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-alanine transport, L-serine transport, amino acid transport, erythrocyte differentiation, iron ion transport, monoatomic ion transmembrane transport, monoatomic ion transport, one-carbon metabo...
Does Knockout of Gm3500 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Gm3500
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gm3500 (predicted gene 3500) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A0AA74KT55, A6NAS7 Entrez ID: 100041678
Does Knockout of Ercc5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Ercc5
cell proliferation
Mouse kidney carcinoma cell
Gene: Ercc5 (excision repair cross-complementing rodent repair deficiency, complementation group 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, UV protection, base-excision repair, AP site formation, determination of adult lifespan, do...
Does Knockout of Pin4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Pin4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pin4 (peptidyl-prolyl cis/trans isomerase, NIMA-interacting, 4 (parvulin)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: rRNA processing; MF: DNA binding, bent DNA binding, double-stranded DNA binding, isomerase activity, peptidyl-prolyl cis-trans isomerase activi...
Does Knockout of Dph6 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Dph6
cell proliferation
Mouse kidney carcinoma cell
Gene: Dph6 (diphthamine biosynthesis 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein histidyl modification to diphthamide; MF: ATP binding, diphthine-ammonia ligase activity, ligase activity, nucleotide binding Pathways: Gamma carboxylation, hypusinyla...
Does Knockout of Chd6 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Chd6
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Chd6 (chromodomain helicase DNA binding protein 6) Type: protein-coding Summary: This gene encodes a member of the chromodomain/helicase/DNA-binding domain family of chromatin remodeling enzymes. This protein has been found to be specifically involved in transcription initiation and elongation. Ho...
Does Knockout of Ccrl2 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Ccrl2
cell viability
Immortal mouse chromaffin cells
Gene: Ccrl2 (C-C motif chemokine receptor-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, calcium-mediated signaling, cell chemotaxis, chemokine-mediated signaling pathway, chemotaxis, immune response, inflammatory res...
Does Knockout of Tex2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Tex2
cell proliferation
Mouse kidney carcinoma cell
Gene: Tex2 (testis expressed gene 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, lipid transport; MF: lipid binding, molecular_function; CC: endoplasmic reticulum, endoplasmic reticulum membrane, membrane, nuclear membrane, nucleus Pathway...
Does Knockout of Cd200r3 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Cd200r3
response to chemicals
Pancreatic Cancer Cell Line
Gene: Cd200r3 (CD200 receptor 3) Type: protein-coding Summary: No summary available. Gene Ontology: MF: protein binding, signaling receptor activity; CC: cell surface, external side of plasma membrane, membrane, plasma membrane Pathways: Kaposi sarcoma-associated herpesvirus infection ...
Does Knockout of Thoc6 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Thoc6
cell proliferation
Embryonic Stem Cell Line
Gene: Thoc6 (THO complex 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, apoptotic process, central nervous system development, mRNA export from nucleus, mRNA processing, mRNA transport; MF: RNA binding, protein binding; CC: THO complex, THO complex part ...
Does Knockout of Kif27 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Kif27
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Kif27 (kinesin family member 27) Type: protein-coding Summary: Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in cilium assembly. Acts upstream of or within epithelial cilium movement involved in extracellular fluid movement; est...
Does Knockout of Tex28 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Tex28
cell proliferation
Embryonic Stem Cell Line
Gene: Tex28 (testis expressed 28) Type: protein-coding Summary: No summary available. Gene Ontology: CC: endomembrane system, membrane Pathways: UniProt: B1AYN9 Entrez ID: 385380
Does Knockout of Pds5a in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Pds5a
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Pds5a (PDS5 cohesin associated factor A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterior/posterior pattern specification, cell division, embryonic skeletal system morphogenesis, enteric nervous system development, heart morphogenesis, lens development in ca...
Does Knockout of Nutf2-ps1 in macrophage causally result in phagocytosis?
1
1,888
Knockout
Nutf2-ps1
phagocytosis
macrophage
Gene: Nutf2-ps1 (nuclear transport factor 2, pseudogene 1) Type: pseudo Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 100043462
Does Knockout of Pold3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Pold3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pold3 (polymerase (DNA-directed), delta 3, accessory subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA biosynthetic process, DNA damage response, DNA repair, DNA replication, DNA strand elongation involved in DNA replication, DNA synthesis involved in UV-...
Does Knockout of Zc3hc1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Zc3hc1
cell proliferation
Colonic Cancer Cell Line
Gene: Zc3hc1 (zinc finger, C3HC type 1) Type: protein-coding Summary: Predicted to enable protein kinase binding activity. Predicted to be involved in cell division and protein ubiquitination. Located in nucleus. Orthologous to human ZC3HC1 (zinc finger C3HC-type containing 1). [provided by Alliance of ...
Does Knockout of Pramel1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Pramel1
cell proliferation
Embryonic Stem Cell Line
Gene: Pramel1 (PRAME like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, negative regulation of DNA-templated transcription, negative regulation of apoptotic process, negative regulation of cell differentiation, positive regulation of cell populati...
Does Knockout of Unk in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Unk
cell cycle progression
breast epithelium
Gene: Unk (unkempt family zinc finger) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell morphogenesis involved in neuron differentiation, in utero embryonic development, negative regulation of cytoplasmic translation, neuron migration, regulation of translation; MF: R...
Does Knockout of Uimc1 in Lymphoma Cell Line causally result in response to chemicals?
1
1,558
Knockout
Uimc1
response to chemicals
Lymphoma Cell Line
Gene: Uimc1 (ubiquitin interaction motif containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, chromatin organization, double-strand break repair, mitotic G2 DNA damage checkpoint signalin...
Does Knockout of Ccdc149 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Ccdc149
protein/peptide accumulation
Regulatory T cell
Gene: Ccdc149 (coiled-coil domain containing 149) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A0A0G2JF66, F6V035, A0A1D5RM99 Entrez ID: 100503884
Does Knockout of Ercc2 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Ercc2
cell proliferation
Melanoma Cell Line
Gene: Ercc2 (excision repair cross-complementing rodent repair deficiency, complementation group 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA-templated transcription, UV protection, apoptotic process, bone mineralization, central...
Does Knockout of Gjb3 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Gjb3
phagocytosis
macrophage
Gene: Gjb3 (gap junction protein, beta 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell communication, cell-cell signaling, placenta development, transmembrane transport; MF: gap junction channel activity, protein binding; CC: anchoring junction, cell junction, cel...
Does Knockout of Znhit2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Znhit2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Znhit2 (zinc finger, HIT domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, zinc ion binding Pathways: UniProt: Q9QY66 Entrez ID: 29805
Does Knockout of Rps10 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Rps10
response to virus
Microglial Cell Line
Gene: Rps10 (ribosomal protein S10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, ribosomal small subunit assembly, translation at postsynapse, translation at presynapse; MF: RNA binding, structural constituent of ribosome, tRNA binding; CC: cyt...
Does Knockout of Clpp in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Clpp
cell proliferation
Colonic Cancer Cell Line
Gene: Clpp (caseinolytic mitochondrial matrix peptidase proteolytic subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: membrane protein proteolysis, protein quality control for misfolded or incompletely synthesized proteins, proteolysis, proteolysis involved in prot...
Does Knockout of Mlh3 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,278
Knockout
Mlh3
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Mlh3 (mutL homolog 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, female meiosis I, intracellular protein localization, male meiotic nuclear division, mismatch repair, synaptonemal complex assembly; MF: ATP binding, ATP hydrolysis activity, ...
Does Knockout of Prelid3a in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Prelid3a
response to chemicals
Pancreatic Cancer Cell Line
Gene: Prelid3a (PRELI domain containing 3A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intermembrane lipid transfer, lipid transport, phospholipid transport; MF: phosphatidic acid transfer activity; CC: mitochondrial intermembrane space, mitochondrion Pathwa...
Does Knockout of Zfp446 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Zfp446
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Zfp446 (zinc finger protein 446) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding Pathways: Gene expression (Transcri...
Does Knockout of Fbxo40 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Fbxo40
protein/peptide distribution
myoblast cell line
Gene: Fbxo40 (F-box protein 40) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, muscle cell differentiation; MF: metal ion binding, molecular_function, ubiquitin protein ligase activity, zinc ion binding; CC: cytoplasm Pathways: Adaptive Immun...
Does Knockout of Arf6 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Arf6
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Arf6 (ARF GTPase 6) Type: protein-coding Summary: Predicted to enable several functions, including G protein activity; guanyl ribonucleotide binding activity; and thioesterase binding activity. Involved in several processes, including positive regulation of focal adhesion disassembly; positive reg...
Does Knockout of Rbm17 in Lymphoma Cell Line causally result in response to chemicals?
0
1,549
Knockout
Rbm17
response to chemicals
Lymphoma Cell Line
Gene: Rbm17 (RNA binding motif protein 17) Type: protein-coding Summary: Predicted to enable RNA binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome. Located in nucleus. Part of protein-containing complex. Is expressed in brain; cerebral cortex; hippocampus; ovary; a...
Does Knockout of Eif4a3 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Eif4a3
tumorigenicity
Colonic Cancer Cell Line
Gene: Eif4a3 (eukaryotic translation initiation factor 4A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, embryonic cranial skeleton morphogenesis, mRNA export from nucleus, mRNA processing, mRNA splicing, via spliceosome, mRNA transport, negative regulati...
Does Knockout of Ndrg4 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Ndrg4
cell proliferation
Mouse kidney carcinoma cell
Gene: Ndrg4 (N-myc downstream regulated gene 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell migration involved in heart development, negative regulation of platelet-derived growth factor receptor signaling pathway, negative regulation of smooth muscle cell migrat...
Does Knockout of Hdac5 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Hdac5
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Hdac5 (histone deacetylase 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation, B cell differentiation, cellular response to fluid shear stress, chromatin organization, epigenetic regulation of gene expression, heart development, inflammatory respon...
Does Knockout of Rab7 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Rab7
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Rab7 (RAB7, member RAS oncogene family) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, autophagy, bone resorption, early endosome to late endosome transport, endosome to lysosome transport, endosome to plasma membrane protein transport, epid...
Does Knockout of Cyp2c70 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,440
Knockout
Cyp2c70
protein/peptide accumulation
Embryonic Cell Line
Gene: Cyp2c70 (cytochrome P450, family 2, subfamily c, polypeptide 70) Type: protein-coding Summary: No summary available. Gene Ontology: BP: epoxygenase P450 pathway, xenobiotic catabolic process; MF: heme binding, iron ion binding, metal ion binding, monooxygenase activity, oxidoreductase act...
Does Knockout of Ddx49 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Ddx49
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ddx49 (DEAD box helicase 49) Type: protein-coding Summary: Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be involved in positive regulation of cell growth; rRNA processing; and regulation of rRNA stability. P...
Does Knockout of Dtl in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,287
Knockout
Dtl
cell proliferation
Mouse kidney carcinoma cell
Gene: Dtl (denticleless E3 ubiquitin protein ligase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA replication, mitotic G2 DNA damage checkpoint signaling, positive regulation of G2/M transition of mitotic cell cycle, positive regulation of cata...
Does Knockout of Arglu1 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Arglu1
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Arglu1 (arginine and glutamate rich 1) Type: protein-coding Summary: Enables pre-mRNA binding activity and transcription coactivator activity. Involved in regulation of alternative mRNA splicing, via spliceosome. Located in nuclear speck. Is expressed in several structures, including brain; genito...
Does Knockout of Hbp1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Hbp1
protein/peptide accumulation
Regulatory T cell
Gene: Hbp1 (high mobility group box transcription factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, negative regulation of lipid transport, negative regulation of macrophage derived foam cell differentiation, negative regulation of reactive ...
Does Knockout of Ccdc93 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Ccdc93
cell proliferation
Mouse kidney carcinoma cell
Gene: Ccdc93 (coiled-coil domain containing 93) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to plasma membrane transport, endocytic recycling, protein transport; CC: early endosome, endosome Pathways: UniProt: Q7TQK5 Entrez ID: 70829
Does Knockout of Slc30a3 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Slc30a3
protein/peptide accumulation
Embryonic Cell Line
Gene: Slc30a3 (solute carrier family 30 (zinc transporter), member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: detoxification of zinc ion, monoatomic cation transport, monoatomic ion transport, positive regulation of transport, response to zinc ion, transmembrane t...
Does Knockout of B4galnt4 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
B4galnt4
autophagy
Embryonic Fibroblast Cell Line
Gene: B4galnt4 (beta-1,4-N-acetyl-galactosaminyl transferase 4) Type: protein-coding Summary: No summary available. Gene Ontology: MF: N-acetyl-beta-glucosaminyl-derivative 4-beta-N-acetylgalactosaminyltransferase activity, acetylgalactosaminyltransferase activity, glucuronosyl-N-acetylgalactos...
Does Knockout of Vnn1 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Vnn1
cell viability
Immortal mouse chromaffin cells
Gene: Vnn1 (vanin 1) Type: protein-coding Summary: Enables pantetheine hydrolase activity. Involved in several processes, including coenzyme A catabolic process; positive regulation of T cell differentiation in thymus; and positive regulation of oxidative stress-induced intrinsic apoptotic signaling pat...
Does Knockout of Atp6v1e1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Atp6v1e1
cell proliferation
Colonic Cancer Cell Line
Gene: Atp6v1e1 (ATPase, H+ transporting, lysosomal V1 subunit E1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transport, proton transmembrane transport, synaptic vesicle lumen acidification; MF: ATPase binding, protein binding, proton-transporting ATPas...
Does Knockout of Cybb in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Cybb
protein/peptide distribution
myoblast cell line
Gene: Cybb (cytochrome b-245, beta polypeptide) Type: protein-coding Summary: This gene encodes the heavy chain component of a heterodimeric transmembrane ion transporter composed of both a heavy and a light chain. This transporter mediates the transfer of electrons from nicotinamide adenine dinucleotid...
Does Knockout of Bcl3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Bcl3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Bcl3 (B cell leukemia/lymphoma 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA damage response, signal transduction by p53 class mediator, T-helper 1 type immune response, T-helper 2 cell differentiation, antimicrobial humoral response, a...
Does Knockout of Mir6420 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Mir6420
cell cycle progression
breast epithelium
Gene: Mir6420 (microRNA 6420) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Emc3 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Emc3
protein/peptide distribution
myoblast cell line
Gene: Emc3 (ER membrane protein complex subunit 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein insertion into ER membrane by stop-transfer membrane-anchor sequence, tail-anchored membrane protein insertion into ER membrane; MF: membrane insertase activity; CC:...
Does Knockout of Cd47 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Cd47
protein/peptide distribution
myoblast cell line
Gene: Cd47 (CD47 antigen (Rh-related antigen, integrin-associated signal transducer)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ATP export, angiogenesis, apoptotic process, cell adhesion, cell migration, cell-cell adhesion, cellular response to interleukin-1, cellul...
Does Knockout of Ptgis in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Ptgis
cell proliferation
Mouse kidney carcinoma cell
Gene: Ptgis (prostaglandin I2 (prostacyclin) synthase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic signaling pathway, cellular response to hypoxia, cellular response to interleukin-1, cellular response to interleukin-6, cyclooxygenase pathway, decidualizatio...
Does Knockout of Bsg in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Bsg
protein/peptide accumulation
Embryonic Cell Line
Gene: Bsg (basigin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, axon guidance, cell differentiation, decidualization, dendrite self-avoidance, embryo implantation, endothelial tube morphogenesis, homophilic cell adhesion via plasma membrane adhesion mole...
Does Knockout of Adamts2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Adamts2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Adamts2 (ADAM metallopeptidase with thrombospondin type 1 motif 2) Type: protein-coding Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin repeats) family of proteinases that is involved in the proteolytic processing of procollagens. The enco...
Does Knockout of Il13ra1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Il13ra1
cell proliferation
Embryonic Stem Cell Line
Gene: Il13ra1 (interleukin 13 receptor, alpha 1) Type: protein-coding Summary: This gene encodes a transmembrane protein that complexes with interleukin 4 receptor alpha (IL4RA) to form a functional receptor for interleukin-13. Signalling through this pathway mediates allergy response and occurs during ...
Does Knockout of Pim1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Pim1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pim1 (proviral integration site 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cellular detoxification, cellular response to amino acid starvation, cellular response to nutrient levels, cellular response to type II interferon, cytolysis in ano...
Does Knockout of Isg20 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Isg20
cell proliferation
Colonic Cancer Cell Line
Gene: Isg20 (interferon-stimulated protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA catabolic process, RNA catabolic process, RNA processing, defense response to virus, immune system process, innate immune response, negative regulation of viral genome replicat...
Does Knockout of Cela3a in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Cela3a
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Cela3a (chymotrypsin-like elastase family, member 3A) Type: protein-coding Summary: Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. Orthologous to several human genes including CELA3B (chymotrypsin like...
Does Knockout of Ccr4 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Ccr4
cell proliferation
Mouse kidney carcinoma cell
Gene: Ccr4 (C-C motif chemokine receptor 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, calcium-mediated signaling, cell chemotaxis, chemokine-mediated signaling pathway, chemotaxis, homeostasis of number of cells, immune ...
Does Knockout of Acp6 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Acp6
cell proliferation
Embryonic Stem Cell Line
Gene: Acp6 (acid phosphatase 6, lysophosphatidic) Type: protein-coding Summary: No summary available. Gene Ontology: BP: hematopoietic progenitor cell differentiation, lipid metabolic process, lysobisphosphatidic acid metabolic process, phospholipid metabolic process; MF: acid phosphatase activ...
Does Knockout of Vmn1r104 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Vmn1r104
protein/peptide accumulation
Embryonic Cell Line
Gene: Vmn1r104 (vomeronasal 1 receptor 104) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled recepto...
Does Knockout of Kif11 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Kif11
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Kif11 (kinesin family member 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, microtubule-based movement, mitotic centrosome separation, mitotic nuclear division, mitotic spindle assembly, regulation of mitotic centrosome separation, spindle assemb...
Does Knockout of Syk in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Syk
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Syk (spleen tyrosine kinase) Type: protein-coding Summary: Enables several functions, including ATP binding activity; SH2 domain binding activity; and enzyme binding activity. Involved in several processes, including cell surface receptor signaling pathway; myeloid cell activation involved in immu...
Does Knockout of Palb2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Palb2
cell viability
Immortal mouse chromaffin cells
Gene: Palb2 (partner and localizer of BRCA2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, animal organ morphogenesis, double-strand break repair via homologous recombination, embryonic organ development, in utero embr...
Does Knockout of Slc47a1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Slc47a1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Slc47a1 (solute carrier family 47, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-alpha-amino acid transmembrane transport, L-arginine import across plasma membrane, L-arginine transmembrane transport, amino acid import across plasma membrane, monoatomi...
Does Knockout of Vmn1r238 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Vmn1r238
cell viability
Immortal mouse chromaffin cells
Gene: Vmn1r238 (vomeronasal 1 receptor, 238) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled recept...
Does Knockout of Mcrs1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Mcrs1
cell proliferation
Melanoma Cell Line
Gene: Mcrs1 (microspherule protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, chromatin organization, chromatin remodeling, negative regulation of telomere maintenance via telomere lengthening, positive regulatio...
Does Knockout of Rnaseh2a in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,171
Knockout
Rnaseh2a
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Rnaseh2a (ribonuclease H2, large subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, removal of RNA primer, RNA catabolic process, RNA metabolic process, mismatch repair; MF: RNA binding, RNA-DNA hybrid ribonuclease activity, endonuclease activ...
Does Knockout of Tas2r140 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Tas2r140
response to virus
Embryonic Fibroblast Cell Line
Gene: Tas2r140 (taste receptor, type 2, member 140) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of bitter taste, detection of chemical stimulus involved in sens...
Does Knockout of Rbsn in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Rbsn
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rbsn (rabenosyn, RAB effector) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to lysosome transport, early endosome to Golgi transport, protein transport, regulation of Golgi organization; MF: metal ion binding, phosphatidylinositol-3-phosphate binding, small...
Does Knockout of Psma6 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Psma6
cell proliferation
Embryonic Stem Cell Line
Gene: Psma6 (proteasome subunit alpha 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of canonical NF-kappaB signal transduction, proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis involved in protein catabolic process, r...
Does Knockout of Pak4 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Pak4
cell proliferation
Embryonic Stem Cell Line
Gene: Pak4 (p21 (RAC1) activated kinase 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cellular response to starvation, dendritic spine development, intracellular signal transduction, negative regulation of endothelial cell apoptotic process, positi...
Does Knockout of Sec23a in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Sec23a
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Sec23a (SEC23 homolog A, COPII coat complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: COPII-coated vesicle budding, COPII-coated vesicle cargo loading, endoplasmic reticulum to Golgi vesicle-mediated transport, intracellular protein transport, prote...
Does Knockout of Esf1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Esf1
protein/peptide distribution
myoblast cell line
Gene: Esf1 (ESF1 nucleolar pre-rRNA processing protein homolog) Type: protein-coding Summary: No summary available. Gene Ontology: BP: rRNA processing; CC: nucleolus, nucleoplasm, nucleus Pathways: UniProt: Q3V1V3 Entrez ID: 66580
Does Knockout of C2cd3 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
C2cd3
protein/peptide accumulation
Mouse cell
Gene: C2cd3 (C2 calcium-dependent domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, cell projection organization, centriole elongation, cilium assembly, embryonic digit morphogenesis, embryonic limb morphogenesis, heart looping, in ut...
Does Knockout of Smad6 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Smad6
cell proliferation
Mouse kidney carcinoma cell
Gene: Smad6 (SMAD family member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: BMP signaling pathway, SMAD protein signal transduction, anatomical structure morphogenesis, aorta development, aortic valve morphogenesis, cardiac vascular smooth muscle cell development, ...
Does Knockout of Csrnp2 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,440
Knockout
Csrnp2
protein/peptide accumulation
Embryonic Cell Line
Gene: Csrnp2 (cysteine-serine-rich nuclear protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription...
Does Knockout of Ints13 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,287
Knockout
Ints13
cell proliferation
Mouse kidney carcinoma cell
Gene: Ints13 (integrator complex subunit 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II transcription initiation surveillance, cell division, centrosome localization, flagellated sperm motility, mitotic spindle organization, protein localization to ...
Does Knockout of Txnrd1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Txnrd1
cell proliferation
Colonic Cancer Cell Line
Gene: Txnrd1 (thioredoxin reductase 1) Type: protein-coding Summary: The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocys...
Does Knockout of Cdca3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Cdca3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cdca3 (cell division cycle associated 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, protein ubiquitination; CC: adherens junction, cytoplasm, cytosol Pathways: UniProt: Q99M54 Entrez ID: 14793
Does Knockout of Gpc1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Gpc1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Gpc1 (glypican 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Schwann cell differentiation, cell migration, heparan sulfate proteoglycan catabolic process, myelin assembly, negative regulation of fibroblast growth factor receptor signaling pathway, positive regu...
Does Knockout of Traf6 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Traf6
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Traf6 (TNF receptor-associated factor 6) Type: protein-coding Summary: This gene encodes a member of the TNF receptor associated factor (TRAF) family of adaptor proteins that mediate signaling events from members of the TNF receptor and Toll/IL-1 receptor families to activate transcription factors...
Does Knockout of Mus81 in Lymphoma Cell Line causally result in response to chemicals?
1
1,545
Knockout
Mus81
response to chemicals
Lymphoma Cell Line
Gene: Mus81 (MUS81 structure-specific endonuclease subunit) Type: protein-coding Summary: Predicted to enable 3'-flap endonuclease activity. Predicted to contribute to crossover junction DNA endonuclease activity. Predicted to be involved in DNA metabolic process; mitotic intra-S DNA damage checkpoint s...
Does Knockout of B230217C12Rik in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
B230217C12Rik
response to chemicals
Pancreatic Cancer Cell Line
Gene: B230217C12Rik (RIKEN cDNA B230217C12 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: E9Q3Z1, A0A1B0GR59 Entrez ID: 68127
Does Knockout of Polr1b in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Polr1b
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Polr1b (polymerase (RNA) I polypeptide B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, embryo implantation, neural crest formation, nucleologenesis, rRNA transcription; MF: 5'-3' RNA polymerase activity, DNA binding, DNA-directed RNA ...
Does Knockout of Topors in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Topors
protein/peptide distribution
myoblast cell line
Gene: Topors (topoisomerase I binding, arginine/serine-rich) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, intrinsic apoptotic signaling pathway in response to DNA damage, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class ...
Does Knockout of Sspo in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Sspo
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Sspo (SCO-spondin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, cell adhesion; MF: extracellular matrix structural constituent, molecular_function; CC: cytoplasm, extracellular matrix, extracellular region, extracellular space Pathway...
Does Knockout of Dimt1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Dimt1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Dimt1 (DIM1 rRNA methyltransferase and ribosome maturation factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: methylation, positive regulation of rRNA processing, rRNA methylation, rRNA modification, rRNA processing, ribosomal small subunit biogenesis; MF: 18S ...
Does Knockout of Ube2m in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Ube2m
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ube2m (ubiquitin-conjugating enzyme E2M) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of neuron apoptotic process, protein modification process, protein neddylation, regulation of postsynapse assembly; MF: ATP binding, NEDD8 conjugating enzyme...
Does Knockout of Ak6 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Ak6
cell proliferation
Mouse kidney carcinoma cell
Gene: Ak6 (adenylate kinase 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nucleoside monophosphate phosphorylation, rRNA processing, ribosomal small subunit biogenesis, ribosome biogenesis; MF: AMP kinase activity, ATP binding, ATP hydrolysis activity, kinase activit...