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Does Knockout of Peli3 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Peli3
protein/peptide distribution
myoblast cell line
Gene: Peli3 (pellino 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to Gram-negative bacterium, immune system process, innate immune response, negative regulation of Toll signaling pathway, negative regulation of extrinsic apoptotic signaling pathway,...
Does Knockout of Rpn2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Rpn2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Rpn2 (ribophorin II) Type: protein-coding Summary: Predicted to enable ribosome binding activity. Acts upstream of or within protein N-linked glycosylation. Predicted to be located in autophagosome membrane; endoplasmic reticulum; and nuclear body. Predicted to be part of oligosaccharyltransferase...
Does Knockout of Pira4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Pira4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pira4 (paired-Ig-like receptor A4) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: B cell receptor signaling pathway - Mus musculus (mouse), Osteoclast differentiation - Mus musculus (mouse) UniProt: A2NTK1 Entrez ID: 18727
Does Knockout of Slc25a36 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Slc25a36
cell proliferation
Embryonic Stem Cell Line
Gene: Slc25a36 (solute carrier family 25, member 36) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrion organization, nucleotide transport, pyrimidine nucleotide import into mitochondrion, pyrimidine nucleotide transport, regulation of mitochondrial membrane po...
Does Knockout of Arl8a in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Arl8a
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Arl8a (ADP-ribosylation factor-like 8A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterograde axonal transport, cell division, chromosome segregation, protein transport; MF: GTP binding, GTPase activity, nucleotide binding; CC: axon, axon cytoplasm, cell proje...
Does Knockout of Apold1 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Apold1
phagocytosis
macrophage
Gene: Apold1 (apolipoprotein L domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, autophagosome-dependent secretion, lipid transport, lipoprotein metabolic process, regulation of endothelial cell differentiation, regulation of membrane perm...
Does Knockout of Il23a in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Il23a
protein/peptide accumulation
Embryonic Cell Line
Gene: Il23a (interleukin 23, alpha subunit p19) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell proliferation, cell surface receptor signaling pathway via JAK-STAT, cell surface receptor signaling pathway via STAT, defense response to Gram-negative bacterium, defen...
Does Knockout of Spint3 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Spint3
cell viability
Immortal mouse chromaffin cells
Gene: Spint3 (serine peptidase inhibitor, Kunitz type, 3) Type: protein-coding Summary: No summary available. Gene Ontology: MF: peptidase inhibitor activity, serine-type endopeptidase inhibitor activity; CC: extracellular region, extracellular space Pathways: UniProt: Q3UW09...
Does Knockout of Ncf4 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Ncf4
protein/peptide distribution
myoblast cell line
Gene: Ncf4 (neutrophil cytosolic factor 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: phagocytosis, respiratory burst, superoxide anion generation; MF: lipid binding, phosphatidylinositol binding, phosphatidylinositol-3-phosphate binding, protein binding, superoxide-...
Does Knockout of Cflar in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Cflar
response to virus
Embryonic Fibroblast Cell Line
Gene: Cflar (CASP8 and FADD-like apoptosis regulator) Type: protein-coding Summary: Enables peptidase activator activity. Involved in several processes, including negative regulation of myoblast fusion; positive regulation of NF-kappaB transcription factor activity; and skeletal muscle atrophy. Acts ups...
Does Knockout of Slc38a7 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Slc38a7
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Slc38a7 (solute carrier family 38, member 7) Type: protein-coding Summary: Enables L-glutamine:sodium symporter activity. Involved in glutamine transport and sodium ion transport. Located in axon and neuronal cell body. Is expressed in several structures, including alimentary system; central nervo...
Does Knockout of Speer4d in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Speer4d
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Speer4d (spermatogenesis associated glutamate (E)-rich protein 4D) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9D3W2, L7N216, L7N261 Entrez ID: 360220
Does Knockout of Srsf12 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Srsf12
cell cycle progression
breast epithelium
Gene: Srsf12 (serine and arginine-rich splicing factor 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA 5'-splice site recognition, mRNA processing, regulation of alternative mRNA splicing, via spliceosome Pathways: UniProt: Q8C8K3...
Does Knockout of Rtf1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Rtf1
cell proliferation
Embryonic Stem Cell Line
Gene: Rtf1 (RTF1, Paf1/RNA polymerase II complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, blastocyst growth, chromatin organization, endodermal cell fate commitment, negative regulation of transcription by RNA polymerase II, stem c...
Does Knockout of Dhdds in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Dhdds
protein/peptide accumulation
Regulatory T cell
Gene: Dhdds (dehydrodolichyl diphosphate synthase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: dolichyl diphosphate biosynthetic process, dolichyl monophosphate biosynthetic process, lipid metabolic process, polyprenol biosynthetic process, protein glycosylation; MF: ...
Does Knockout of Chrdl2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Chrdl2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Chrdl2 (chordin-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cartilage development, cell differentiation, chondrocyte differentiation, negative regulation of BMP signaling pathway, ossification, system development; MF: BMP binding, protein binding ...
Does Knockout of Skint3 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Skint3
cell proliferation
Colonic Cancer Cell Line
Gene: Skint3 (selection and upkeep of intraepithelial T cells 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell activation, T cell receptor signaling pathway, regulation of T cell activation, regulation of cytokine production, regulation of leukocyte cell-cell adh...
Does Knockout of Sod2 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Sod2
protein/peptide distribution
myoblast cell line
Gene: Sod2 (superoxide dismutase 2, mitochondrial) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure, apoptotic mitochondrial changes, cellular response to ethanol, cellular respo...
Does Knockout of Krtap31-1 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Krtap31-1
cell cycle progression
breast epithelium
Gene: Krtap31-1 (keratin associated protein 31-1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, hair cycle; CC: cellular_component, cytosol, intermediate filament, keratin filament Pathways: Developmental Biology, Keratinization Uni...
Does Knockout of Anapc7 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Anapc7
cell proliferation
Colonic Cancer Cell Line
Gene: Anapc7 (anaphase promoting complex subunit 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anaphase-promoting complex-dependent catabolic process, brain development, cell division, positive regulation of mitotic metaphase/anaphase transition, protein K11-linked u...
Does Knockout of Rpap1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Rpap1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rpap1 (RNA polymerase II associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, nucleotidyltransferase activity, transferase activity; CC: DNA-directed RNA polymerase complex, RNA polymerase complex, nucleus Pathways: U...
Does Knockout of Cyp4a31 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Cyp4a31
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cyp4a31 (cytochrome P450, family 4, subfamily a, polypeptide 31) Type: protein-coding Summary: Predicted to enable monooxygenase activity. Predicted to be involved in several processes, including fatty acid metabolic process; icosanoid metabolic process; and positive regulation of icosanoid secret...
Does Knockout of Hlx in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Hlx
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Hlx (H2.0-like homeobox) Type: protein-coding Summary: Predicted to enable sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic digestive tract morphogenesis; enteric nervous system development; and regulation of T-helper cell differentiation. P...
Does Knockout of Pkp2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,278
Knockout
Pkp2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Pkp2 (plakophilin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adherens junction maintenance, bundle of His cell-Purkinje myocyte adhesion involved in cell communication, cardiac muscle cell action potential, cardiac muscle cell action potential involved in co...
Does Knockout of Yrdc in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Yrdc
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Yrdc (yrdC domain containing (E.coli)) Type: protein-coding Summary: Predicted to enable L-threonylcarbamoyladenylate synthase and tRNA binding activity. Predicted to be involved in regulation of translational fidelity and tRNA threonylcarbamoyladenosine modification. Predicted to act upstream of ...
Does Knockout of Pygo2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,172
Knockout
Pygo2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Pygo2 (pygopus 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: kidney development, spermatid nucleus differentiation Pathways: Formation of the beta-catenin:TCF transactivating complex, Signal Transduction, Signaling by WNT, TCF dependent signaling in re...
Does Knockout of Krtap13-1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Krtap13-1
autophagy
Embryonic Fibroblast Cell Line
Gene: Krtap13-1 (keratin associated protein 13-1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, cytosol, intermediate filament, keratin filament Pathways: Developmental Biology, Keratinization UniProt: Q8K198 Entrez ID: 2689...
Does Knockout of Arid1b in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Arid1b
cell viability
Immortal mouse chromaffin cells
Gene: Arid1b (AT-rich interaction domain 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, dendritic cell dendrite assembly, dendritic spine development, nervous system development, neuron-neuron synaptic transmission, posit...
Does Knockout of Acmsd in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Acmsd
autophagy
Embryonic Fibroblast Cell Line
Gene: Acmsd (amino carboxymuconate semialdehyde decarboxylase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-tryptophan catabolic process, negative regulation of quinolinate biosynthetic process, quinolinate metabolic process, secondary metabolic process; MF: aminocar...
Does Knockout of Ubl4a in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ubl4a
cell proliferation
Embryonic Stem Cell Line
Gene: Ubl4a (ubiquitin-like 4A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: post-translational protein targeting to endoplasmic reticulum membrane, regulation of protein stability, tail-anchored membrane protein insertion into ER membrane, ubiquitin-dependent protein ...
Does Knockout of F13a1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
F13a1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: F13a1 (coagulation factor XIII, A1 subunit) Type: protein-coding Summary: This gene encodes subunit A of the coagulation factor XIII that catalyzes the final step of the blood coagulation pathway. The encoded protein associates with subunit B to form a heterotetrameric proenzyme that undergoes thr...
Does Knockout of Tmem41b in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Tmem41b
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Tmem41b (transmembrane protein 41B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, autophagy, host-mediated perturbation of viral RNA genome replication, intracellular lipid transport, lipid transport, nervous system development, plasma memb...
Does Knockout of Rock2 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Rock2
response to virus
Embryonic Fibroblast Cell Line
Gene: Rock2 (Rho-associated coiled-coil containing protein kinase 2) Type: protein-coding Summary: Enables protein serine/threonine kinase activity. Involved in several processes, including negative regulation of nitric oxide biosynthetic process; positive regulation of macromolecule metabolic process; ...
Does Knockout of Ccdc115 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Ccdc115
protein/peptide distribution
myoblast cell line
Gene: Ccdc115 (coiled-coil domain containing 115) Type: protein-coding Summary: Predicted to enable unfolded protein binding activity. Predicted to be involved in cellular response to increased oxygen levels; intracellular monoatomic cation homeostasis; and lysosomal protein catabolic process. Located i...
Does Knockout of Thoc5 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Thoc5
cell proliferation
Embryonic Stem Cell Line
Gene: Thoc5 (THO complex 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, blastocyst development, cell differentiation, cell morphogenesis, mRNA export from nucleus, mRNA processing, mRNA transport, monocyte differentiation, negative regulation of macropha...
Does Knockout of Thoc6 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Thoc6
protein/peptide distribution
myoblast cell line
Gene: Thoc6 (THO complex 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, apoptotic process, central nervous system development, mRNA export from nucleus, mRNA processing, mRNA transport; MF: RNA binding, protein binding; CC: THO complex, THO complex part ...
Does Knockout of Ets2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Ets2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ets2 (E26 avian leukemia oncogene 2, 3' domain) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, ectodermal cell fate commitment, mesoderm development, negative regulation of transcription by RNA polymerase II, positive regulation of transcripti...
Does Knockout of Trappc8 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Trappc8
cell proliferation
Mouse kidney carcinoma cell
Gene: Trappc8 (trafficking protein particle complex 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: COPII vesicle coating, Golgi organization, collagen biosynthetic process, endoplasmic reticulum to Golgi vesicle-mediated transport, vesicle tethering; CC: TRAPP complex...
Does Knockout of Fsd1l in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Fsd1l
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Fsd1l (fibronectin type III and SPRY domain containing 1-like) Type: protein-coding Summary: Orthologous to human FSD1L (fibronectin type III and SPRY domain containing 1 like). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: Pathways: UniProt: Q8BY...
Does Knockout of Hoga1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Hoga1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Hoga1 (4-hydroxy-2-oxoglutarate aldolase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glyoxylate catabolic process, glyoxylate metabolic process, oxalate metabolic process, pyruvate biosynthetic process, trans-4-hydroxy-L-proline catabolic process; MF: (4S)-4-...
Does Knockout of Parg in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,440
Knockout
Parg
protein/peptide accumulation
Embryonic Cell Line
Gene: Parg (poly (ADP-ribose) glycohydrolase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ATP generation from poly-ADP-D-ribose, DNA damage response, carbohydrate metabolic process, detection of bacterium, nucleotide-sugar metabolic process, positive regulation of DNA...
Does Knockout of Qtrt2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Qtrt2
cell proliferation
Mouse kidney carcinoma cell
Gene: Qtrt2 (queuine tRNA-ribosyltransferase accessory subunit 2) Type: protein-coding Summary: Predicted to enable protein heterodimerization activity; protein homodimerization activity; and tRNA binding activity. Involved in tRNA-guanine transglycosylation. Located in cytoplasmic side of mitochondrial...
Does Knockout of Zfp2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Zfp2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Zfp2 (zinc finger protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, metal ion binding, zinc ion binding Pathways: Gene ex...
Does Knockout of Ikbkg in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Ikbkg
cell proliferation
Colonic Cancer Cell Line
Gene: Ikbkg (inhibitor of kappaB kinase gamma) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell homeostasis, DNA damage response, anoikis, canonical NF-kappaB signal transduction, defense response to bacterium, establishment of vesicle localization, negative regulat...
Does Knockout of Gm20840 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Gm20840
phagocytosis
macrophage
Gene: Gm20840 (predicted gene, 20840) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 108168599
Does Knockout of Zeb1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Zeb1
cell proliferation
Embryonic Stem Cell Line
Gene: Zeb1 (zinc finger E-box binding homeobox 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, cartilage development, cell differentiation, cellular response to amino acid stimulus, central nervous system development, cochlea morphogenesis, em...
Does Knockout of Ints11 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Ints11
cell proliferation
Melanoma Cell Line
Gene: Ints11 (integrator complex subunit 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II transcription initiation surveillance, snRNA 3'-end processing, snRNA processing, transcription by RNA polymerase II, transcription elongation by RNA polymerase ...
Does Knockout of Trit1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Trit1
cell proliferation
Melanoma Cell Line
Gene: Trit1 (tRNA isopentenyltransferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial tRNA modification, tRNA modification, tRNA processing; MF: ATP binding, metal ion binding, nucleotide binding, tRNA dimethylallyltransferase activity, transferase act...
Does Knockout of Grm5 in Microglial Cell Line causally result in response to virus?
0
1,438
Knockout
Grm5
response to virus
Microglial Cell Line
Gene: Grm5 (glutamate receptor, metabotropic 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled glutamate receptor signaling pathway, G protein-coupled receptor signaling pathway, adenylate cyclase-inhibiting G protein-coupled glutamate receptor signalin...
Does Knockout of Prdm10 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Prdm10
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Prdm10 (PR domain containing 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, metal ion bind...
Does Knockout of Ndufb9 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Ndufb9
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ndufb9 (NADH:ubiquinone oxidoreductase subunit B9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, mitochondrial electron transport, NADH to ubiquinone, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner me...
Does Knockout of Slc44a1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Slc44a1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Slc44a1 (solute carrier family 44, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: choline transport, ethanolamine transport, transmembrane transport; MF: antiporter activity, choline transmembrane transporter activity, ethanolamine transmembrane transport...
Does Knockout of Gjd4 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Gjd4
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Gjd4 (gap junction protein, delta 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell communication, cell-cell signaling, regulation of satellite cell activation involved in skeletal muscle regeneration, transmembrane transport; CC: anchoring junction, connexin ...
Does Knockout of Npy in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Npy
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Npy (neuropeptide Y) Type: protein-coding Summary: This gene encodes a neuropeptide that plays a pivotal role in many physiological functions such as food intake, energy homeostasis, circadian rhythm, and cognition. The encoded protein precursor undergoes proteolytic processing to generate the bio...
Does Knockout of Pcdha6 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Pcdha6
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Pcdha6 (protocadherin alpha 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding; CC: membrane, plasma membrane Pathways: ...
Does Knockout of Insl3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Insl3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Insl3 (insulin-like 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, in utero embryonic development, male gonad development, negative regulation of apoptotic process, negative regulation of...
Does Knockout of Ccr5 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Ccr5
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ccr5 (C-C motif chemokine receptor 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, MAPK cascade, apoptotic process, calcium ion transport, calcium-mediated signaling, cell chemotaxis, cell-cell signaling, cellular res...
Does Knockout of Tbcc in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Tbcc
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tbcc (tubulin-specific chaperone C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: post-chaperonin tubulin folding pathway, protein folding, tubulin complex assembly; MF: GTPase activity, tubulin binding; CC: cytoplasm, cytosol, endoplasmic reticulum, photoreceptor...
Does Knockout of Nub1 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Nub1
protein/peptide distribution
myoblast cell line
Gene: Nub1 (negative regulator of ubiquitin-like proteins 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of proteasomal ubiquitin-dependent protein catabolic process, proteasomal protein catabolic process, protein ubiquitination, proteolysis involv...
Does Knockout of Dnajc17 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Dnajc17
cell proliferation
Melanoma Cell Line
Gene: Dnajc17 (DnaJ heat shock protein family (Hsp40) member C17) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, spliceosomal complex disassembly; MF: RNA binding, nucleic acid binding; CC: cytoplasm, nucleus, sp...
Does Knockout of Fbxl21 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Fbxl21
protein/peptide distribution
myoblast cell line
Gene: Fbxl21 (F-box and leucine-rich repeat protein 21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: entrainment of circadian clock by photoperiod, protein ubiquitination, rhythmic process; CC: SCF ubiquitin ligase complex, cytoplasm, cytosol, nucleus Pathways...
Does Knockout of Sprn in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Sprn
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sprn (shadow of prion protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein import into nucleus; MF: nucleic acid binding; CC: cytosol, membrane, nucleolus, nucleus, plasma membrane, side of membrane, vesicle Pathways: Metabolism of proteins, Pos...
Does Knockout of Mir6373 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Mir6373
response to chemicals
Pancreatic Cancer Cell Line
Gene: Mir6373 (microRNA 6373) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Mall in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Mall
protein/peptide distribution
Microglial Cell Line
Gene: Mall (mal, T cell differentiation protein-like) Type: protein-coding Summary: No summary available. Gene Ontology: CC: Golgi membrane, clathrin-coated vesicle, cytoplasmic vesicle, membrane, membrane raft, plasma membrane Pathways: UniProt: Q91X49 Entrez ID: 228...
Does Knockout of Uqcc1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Uqcc1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Uqcc1 (ubiquinol-cytochrome c reductase complex assembly factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial respiratory chain complex III assembly; CC: cytoplasmic vesicle, membrane, mitochondrial inner membrane, mitochondrion Pathways:...
Does Knockout of Ttc1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ttc1
cell proliferation
Embryonic Stem Cell Line
Gene: Ttc1 (tetratricopeptide repeat domain 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, inflammatory response, positive regulation of inflammatory response, positive regulation of neuroinflammatory response; MF: molecular_function, protein-macro...
Does Knockout of Hdlbp in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
1
1,522
Knockout
Hdlbp
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Hdlbp (high density lipoprotein (HDL) binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cholesterol metabolic process, lipid metabolic process, lipid transport, steroid metabolic process; MF: RNA binding, mRNA binding, nucleic acid binding; CC: cytopl...
Does Knockout of Mcoln2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Mcoln2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Mcoln2 (mucolipin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, calcium ion transmembrane transport, calcium ion transport, calcium-mediated signaling, immune system process, innate immune response, iron ion transmembrane transport, ma...
Does Knockout of Efna5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Efna5
cell proliferation
Mouse kidney carcinoma cell
Gene: Efna5 (ephrin A5) Type: protein-coding Summary: Enables chemorepellent activity; ephrin receptor binding activity; and neurotrophin TRKB receptor binding activity. Involved in several processes, including ephrin receptor signaling pathway; positive regulation of nervous system development; and syn...
Does Knockout of Spink6 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Spink6
cell viability
Immortal mouse chromaffin cells
Gene: Spink6 (serine peptidase inhibitor, Kazal type 6) Type: protein-coding Summary: Enables serine-type endopeptidase inhibitor activity. Acts upstream of or within negative regulation of serine-type endopeptidase activity. Located in extracellular region. Orthologous to human SPINK6 (serine peptidase...
Does Knockout of Stpg4 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Stpg4
protein/peptide distribution
myoblast cell line
Gene: Stpg4 (sperm tail PG rich repeat containing 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, epigenetic programing of male pronucleus, pyrimidine-containing compound catabolic process; MF: chromatin binding, histone binding, protein binding...
Does Knockout of Ano7 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ano7
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ano7 (anoctamin 7) Type: protein-coding Summary: This gene encodes a member of the anoctamin family, which in mammals is comprised of 10 members. Anoctamin proteins are proposed to have eight transmembrane domains with both termini facing the cytoplasm and a C-terminal domain of unknown function. ...
Does Knockout of Tmem201 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Tmem201
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tmem201 (transmembrane protein 201) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, centrosome localization, fibroblast migration, nuclear envelope organization, nuclear migration, nuclear migration along microtubule, positive regulation of endothelial...
Does Knockout of Fam20c in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Fam20c
protein/peptide distribution
myoblast cell line
Gene: Fam20c (FAM20C, golgi associated secretory pathway kinase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biomineral tissue development, dentinogenesis, enamel mineralization, odontoblast differentiation, osteoclast maturation, positive regulation of bone mineraliz...
Does Knockout of Ube2e3 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Ube2e3
protein/peptide distribution
myoblast cell line
Gene: Ube2e3 (ubiquitin-conjugating enzyme E2E 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of gene expression, protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein K63-linked ubiquitination, protein monoubiquitination, p...
Does Knockout of Khnyn in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Khnyn
cell proliferation
Melanoma Cell Line
Gene: Khnyn (KH and NYN domain containing) Type: protein-coding Summary: This gene encodes a protein with a C-terminal RNA modifying domain that belongs to a family of ribonucleases typified by eukaryotic Nedd4-binding protein1 and the bacterial YacP-like nucleases (NYN). The NYN domain shares a common ...
Does Knockout of Zbtb8b in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Zbtb8b
autophagy
Embryonic Fibroblast Cell Line
Gene: Zbtb8b (zinc finger and BTB domain containing 8b) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, metal ion binding, zinc ion binding; CC: cytosol, nucleoplasm, nucleus Path...
Does Knockout of Mvd in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Mvd
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mvd (mevalonate (diphospho) decarboxylase) Type: protein-coding Summary: Predicted to enable Hsp70 protein binding activity; diphosphomevalonate decarboxylase activity; and protein homodimerization activity. Predicted to be involved in isopentenyl diphosphate biosynthetic process, mevalonate pathw...
Does Knockout of Mier2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Mier2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Mier2 (MIER family member 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, histone deacetylase activity, histone deacetylase binding, transcription corepressor activity; CC: cytoplasm, nucleoplasm, nucleus, protein-containing complex Pathways...
Does Knockout of Nlrc5 in Melanoma Cell Line causally result in cell proliferation?
1
1,157
Knockout
Nlrc5
cell proliferation
Melanoma Cell Line
Gene: Nlrc5 (NLR family, CARD domain containing 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to virus, immune system process, innate immune response, negative regulation of NF-kappaB transcription factor activity, negative regulation of type I inter...
Does Knockout of Eif4enif1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Eif4enif1
cell proliferation
Embryonic Stem Cell Line
Gene: Eif4enif1 (eukaryotic translation initiation factor 4E nuclear import factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: P-body assembly, mRNA stabilization, miRNA-mediated gene silencing by inhibition of translation, negative regulation of deadenylation-depe...
Does Knockout of Vps11 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,171
Knockout
Vps11
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Vps11 (VPS11, CORVET/HOPS core subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagy, endosomal vesicle fusion, endosome organization, endosome to lysosome transport, intracellular protein transport, negative regulation of intracellular estrogen recepto...
Does Knockout of Myo9b in macrophage causally result in phagocytosis?
1
1,888
Knockout
Myo9b
phagocytosis
macrophage
Gene: Myo9b (myosin IXb) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rho protein signal transduction, Roundabout signaling pathway, actin filament-based movement, actin-myosin filament sliding, establishment of cell polarity, intracellular signal transduction, lamelli...
Does Knockout of Hrh1 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Hrh1
protein/peptide distribution
myoblast cell line
Gene: Hrh1 (histamine receptor H1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, calcium ion import, calcium ion transmembrane tran...
Does Knockout of Tjp1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Tjp1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Tjp1 (tight junction protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, actomyosin structure organization, adherens junction maintenance, ameloblast differentiation, blastocyst formation, cell-cell adhesion, cell-cell junctio...
Does Knockout of Asns in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Asns
cell proliferation
Mouse kidney carcinoma cell
Gene: Asns (asparagine synthetase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-asparagine biosynthetic process, amino acid biosynthetic process, asparagine biosynthetic process, cellular response to glucose starvation, negative regulation of apoptotic process, posit...
Does Knockout of Tomm22 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Tomm22
cell proliferation
Colonic Cancer Cell Line
Gene: Tomm22 (translocase of outer mitochondrial membrane 22) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular protein transport, positive regulation of apoptotic process, protein import into mitochondrial matrix, protein insertion into mitochondrial membrane...
Does Knockout of Supt5 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Supt5
cell proliferation
Embryonic Stem Cell Line
Gene: Supt5 (suppressor of Ty 5, DSIF elongation factor subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription elongation, negative regulation of DNA-templated transcription, elongation, negative regulation of transcription by RNA polymerase ...
Does Knockout of Srsf1 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Srsf1
response to virus
Microglial Cell Line
Gene: Srsf1 (serine and arginine-rich splicing factor 1) Type: protein-coding Summary: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM...
Does Knockout of Srp9 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Srp9
cell proliferation
Embryonic Stem Cell Line
Gene: Srp9 (signal recognition particle 9) Type: protein-coding Summary: Predicted to enable 7S RNA binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Is expresse...
Does Knockout of Orc5 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Orc5
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Orc5 (origin recognition complex, subunit 5) Type: protein-coding Summary: Predicted to enable DNA replication origin binding activity. Predicted to be involved in DNA replication initiation and regulation of DNA replication. Predicted to act upstream of or within DNA replication. Predicted to be ...
Does Knockout of Eif6 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Eif6
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Eif6 (eukaryotic translation initiation factor 6) Type: protein-coding Summary: The protein encoded by this gene is a eukaryotic translation initiation factor that regulates both ribosome biogenesis and translation, which are rate-limiting factors for cell growth. The encoded protein binds 60S rib...
Does Knockout of Mrpl21 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Mrpl21
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Mrpl21 (mitochondrial ribosomal protein L21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: RNA binding, structural constituent of ribosome; CC: cytoplasm, mitochondrial inner membrane, mitochondrial large ribosomal subun...
Does Knockout of Ncam1 in Melanoma Cell Line causally result in tumorigenicity?
0
615
Knockout
Ncam1
tumorigenicity
Melanoma Cell Line
Gene: Ncam1 (neural cell adhesion molecule 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axonal fasciculation, cell adhesion, cell surface receptor signaling pathway, cellular response to ethanol, commissural neuron axon guidance, epithelial to mesenchymal transition...
Does Knockout of 9330161L09Rik in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
9330161L09Rik
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: 9330161L09Rik (RIKEN cDNA 9330161L09 gene) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Ebp in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Ebp
cell proliferation
Mouse kidney carcinoma cell
Gene: Ebp (EBP cholestenol delta-isomerase) Type: protein-coding Summary: This gene encodes a transmembrane protein that localizes to the endoplasmic reticulum. This protein catalyses the conversion of delta8 to delta7 sterols, an important step in sterol biosynthesis. Mutations in this gene are respons...
Does Knockout of Nrxn2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Nrxn2
cell viability
Immortal mouse chromaffin cells
Gene: Nrxn2 (neurexin II) Type: protein-coding Summary: Enables several functions, including calcium channel regulator activity; cell adhesion molecule binding activity; and neuroligin family protein binding activity. Involved in several processes, including modulation of chemical synaptic transmission;...
Does Knockout of Stpg4 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Stpg4
response to virus
Embryonic Fibroblast Cell Line
Gene: Stpg4 (sperm tail PG rich repeat containing 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, epigenetic programing of male pronucleus, pyrimidine-containing compound catabolic process; MF: chromatin binding, histone binding, protein binding...
Does Knockout of Gfm2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Gfm2
cell proliferation
Embryonic Stem Cell Line
Gene: Gfm2 (G elongation factor, mitochondrial 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, ribosome disassembly, translation; MF: GTP binding, GTPase activity, hydrolase activity, nucleotide binding; CC: mitochondrial matrix, mitochondrio...
Does Knockout of Slitrk5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Slitrk5
cell proliferation
Mouse kidney carcinoma cell
Gene: Slitrk5 (SLIT and NTRK-like family, member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adult behavior, axonogenesis, chemical synaptic transmission, circulatory system development, dendrite morphogenesis, grooming behavior, positive regulation of synapse asse...