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Does Knockout of Cyp3a41b in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Cyp3a41b
protein/peptide distribution
myoblast cell line
Gene: Cyp3a41b (cytochrome P450, family 3, subfamily a, polypeptide 41B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: alkaloid catabolic process, estrogen metabolic process, lipid hydroxylation, oxidative demethylation, regulation of gene expression, response to bacter...
Does Knockout of Pafah1b1 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Pafah1b1
protein/peptide distribution
Microglial Cell Line
Gene: Pafah1b1 (platelet-activating factor acetylhydrolase, isoform 1b, subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acrosome assembly, actin cytoskeleton organization, adult locomotory behavior, ameboidal-type cell migration, auditory receptor cell developm...
Does Knockout of Vmn1r38 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Vmn1r38
cell proliferation
Embryonic Stem Cell Line
Gene: Vmn1r38 (vomeronasal 1 receptor 38) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromone ...
Does Knockout of Sod2 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Sod2
protein/peptide distribution
myoblast cell line
Gene: Sod2 (superoxide dismutase 2, mitochondrial) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure, apoptotic mitochondrial changes, cellular response to ethanol, cellular respo...
Does Knockout of Zfp868 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Zfp868
protein/peptide accumulation
Embryonic Cell Line
Gene: Zfp868 (zinc finger protein 868) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Vmn1r171 in Mouse cell causally result in protein/peptide accumulation?
1
1,047
Knockout
Vmn1r171
protein/peptide accumulation
Mouse cell
Gene: Vmn1r171 (vomeronasal 1 receptor 171) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled recepto...
Does Knockout of Cog1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Cog1
cell proliferation
Embryonic Stem Cell Line
Gene: Cog1 (component of oligomeric golgi complex 1) Type: protein-coding Summary: Predicted to be involved in Golgi organization; glycosylation; and retrograde transport, vesicle recycling within Golgi. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Predicte...
Does Knockout of Ptpn22 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Ptpn22
protein/peptide distribution
myoblast cell line
Gene: Ptpn22 (protein tyrosine phosphatase, non-receptor type 22 (lymphoid)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell differentiation, T cell receptor signaling pathway, autophagy, cellular response to muramyl dipeptide, immune system process, lipid metaboli...
Does Knockout of Wdr37 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Wdr37
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Wdr37 (WD repeat domain 37) Type: protein-coding Summary: No summary available. Gene Ontology: BP: corpus callosum development, lymphocyte homeostasis; MF: molecular_function, protein binding; CC: cytoplasm, nucleus Pathways: UniProt: Q8CBE3 Entrez ID: 207615
Does Knockout of Fmo6 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Fmo6
cell cycle progression
breast epithelium
Gene: Fmo6 (flavin containing monooxygenase 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: taurine biosynthetic process, xenobiotic metabolic process; MF: N,N-dimethylaniline monooxygenase activity, NADP binding, flavin adenine dinucleotide binding, monooxygenase acti...
Does Knockout of Zc3h13 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Zc3h13
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Zc3h13 (zinc finger CCCH type containing 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, regulation of stem cell population maintenance; MF: metal ion binding, zinc ion binding; CC: RNA N6-methyladenosine methyltransferase complex,...
Does Knockout of Agpat5 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Agpat5
protein/peptide distribution
myoblast cell line
Gene: Agpat5 (1-acylglycerol-3-phosphate O-acyltransferase 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CDP-diacylglycerol biosynthetic process, acylglycerol metabolic process, hematopoietic progenitor cell differentiation, lipid metabolic process, phosphatidylinosi...
Does Knockout of Tmco5 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Tmco5
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Tmco5 (transmembrane and coiled-coil domains 5) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, endoplasmic reticulum, endoplasmic reticulum membrane, membrane, nuclear membrane, nucleus Pathways: UniProt: Q9D9D5 Entrez...
Does Knockout of Cxcr3 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Cxcr3
cell proliferation
Embryonic Stem Cell Line
Gene: Cxcr3 (C-X-C motif chemokine receptor 3) Type: protein-coding Summary: This gene encodes a transmembrane protein that functions as a receptor for C-X-R chemokines. Signalling through this protein regulates a variety of biological processes, including inflammation, immunity, and would healing. This...
Does Knockout of Ints6 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Ints6
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ints6 (integrator complex subunit 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II transcription initiation surveillance, protein localization to chromatin, snRNA 3'-end processing, snRNA processing, transcription by RNA polymerase II, transcript...
Does Knockout of Ndufa3 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Ndufa3
protein/peptide accumulation
Mouse cell
Gene: Ndufa3 (NADH:ubiquinone oxidoreductase subunit A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner membrane, mitochondrion, respiratory chain complex I ...
Does Knockout of Nelfe in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Nelfe
cell proliferation
Mouse kidney carcinoma cell
Gene: Nelfe (negative elongation factor complex member E, Rdbp) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, negative regulation of transcription elongation by RNA polymerase II, positive regulation of ERK1 and...
Does Knockout of Gpm6a in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Gpm6a
cell proliferation
Mouse kidney carcinoma cell
Gene: Gpm6a (glycoprotein m6a) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion transmembrane transport, nervous system development, neural retina development, neuron migration, neuron projection development, neuron projection morphogenesis, positive regulation...
Does Knockout of Stk11 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Stk11
cell proliferation
Mouse kidney carcinoma cell
Gene: Stk11 (serine/threonine kinase 11) Type: protein-coding Summary: This gene encodes a member of the serine/threonine kinase family. The encoded protein, a known tumor suppressor, activates (via phosphorylation) adenine monophosphate-activated protein kinase (AMPK) and AMPK-related kinase proteins. ...
Does Knockout of Wdr44 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Wdr44
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Wdr44 (WD repeat domain 44) Type: protein-coding Summary: This gene encodes a protein containing multiple WD repeats. The encoded protein may play a role in vesicle trafficking. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]. Gene Ontology: BP: ...
Does Knockout of Trim32 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Trim32
protein/peptide distribution
myoblast cell line
Gene: Trim32 (tripartite motif-containing 32) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin ubiquitination, autophagosome assembly, axon development, cellular homeostasis, cellular response to amino acid starvation, cellular response to stress, cilium assembly, cy...
Does Knockout of Rpp25l in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Rpp25l
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rpp25l (ribonuclease P/MRP 25 subunit-like) Type: protein-coding Summary: No summary available. Gene Ontology: MF: RNA binding, nucleic acid binding; CC: nucleus, ribonuclease MRP complex Pathways: Ribosome biogenesis in eukaryotes - Mus musculus (mouse) UniProt: Q99JH1 ...
Does Knockout of Rnaseh2b in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Rnaseh2b
cell proliferation
Colonic Cancer Cell Line
Gene: Rnaseh2b (ribonuclease H2, subunit B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA catabolic process, in utero embryonic development, mismatch repair, negative regulation of gene expression, nucleobase-containing compound metabolic process, positive regulatio...
Does Knockout of Prc1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Prc1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Prc1 (protein regulator of cytokinesis 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, microtubule cytoskeleton organization, mitotic spindle midzone assembly, positive regulation of cell population proliferation, regulation of cytokinesis; MF: ide...
Does Knockout of Mastl in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Mastl
protein/peptide distribution
myoblast cell line
Gene: Mastl (microtubule associated serine/threonine kinase-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, G2/M transition of mitotic cell cycle, cell division, female meiosis II, intracellular signal transduction, meiotic cell cycle, mitotic c...
Does Knockout of S100a14 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
S100a14
response to virus
Embryonic Fibroblast Cell Line
Gene: S100a14 (S100 calcium binding protein A14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, defense response to bacterium, positive regulation of granulocyte chemotaxis, positive regulation of monocyte chemotaxis, response to lipopolysaccharide, to...
Does Knockout of Tsc2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
2,173
Knockout
Tsc2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Tsc2 (TSC complex subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-glucose import, TORC1 signaling, anoikis, cell projection organization, cellular response to insulin stimulus, cellular response to nutrient levels, cellular response to starvation, conne...
Does Knockout of Cnot4 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Cnot4
protein/peptide accumulation
Regulatory T cell
Gene: Cnot4 (CCR4-NOT transcription complex, subunit 4) Type: protein-coding Summary: Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein autoubiquitination; regulation of megakaryocyte differentiation; and ubiquitin-dependent protein catabolic process. Predic...
Does Knockout of Mettl6 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Mettl6
protein/peptide distribution
myoblast cell line
Gene: Mettl6 (methyltransferase 6, methylcytidine) Type: protein-coding Summary: No summary available. Gene Ontology: BP: methylation, tRNA methylation, tRNA modification, tRNA processing; MF: enzyme binding, methyltransferase activity, tRNA (cytidine-3-)-methyltransferase activity, transferase...
Does Knockout of Crlf2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Crlf2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Crlf2 (cytokine receptor-like factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytokine-mediated signaling pathway, inflammatory response, positive regulation of cell population proliferation, positive regulation of interleukin-5 production, positive regula...
Does Knockout of Atf4 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Atf4
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Atf4 (activating transcription factor 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GDF15-GFRAL signaling pathway, HRI-mediated signaling, L-asparagine metabolic process, PERK-mediated unfolded protein response, bone mineralization, cellular response to amino a...
Does Knockout of Cul3 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Cul3
cell proliferation
Embryonic Stem Cell Line
Gene: Cul3 (cullin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: COPII vesicle coating, RNA polymerase II transcription initiation surveillance, Wnt signaling pathway, anaphase-promoting complex-dependent catabolic process, apoptotic process, cell division, cell migr...
Does Knockout of Pcdha1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Pcdha1
cell proliferation
Mouse kidney carcinoma cell
Gene: Pcdha1 (protocadherin alpha 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding, molecular_function; CC: endoplasmic reticulum, mem...
Does Knockout of Mrps25 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Mrps25
cell proliferation
Mouse kidney carcinoma cell
Gene: Mrps25 (mitochondrial ribosomal protein S25) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondrion, ribonucleoprotein ...
Does Knockout of Sptlc1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Sptlc1
cell proliferation
Colonic Cancer Cell Line
Gene: Sptlc1 (serine palmitoyltransferase, long chain base subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ceramide biosynthetic process, lipid metabolic process, positive regulation of lipophagy, regulation of fat cell apoptotic process, sphinganine biosynthet...
Does Knockout of Srxn1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Srxn1
protein/peptide accumulation
Embryonic Cell Line
Gene: Srxn1 (sulfiredoxin 1 homolog (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular oxidant detoxification, cellular response to oxidative stress, response to oxidative stress; MF: ATP binding, antioxidant activity, nucleotide binding, oxidoreduc...
Does Knockout of Slc35e1 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Slc35e1
cell proliferation
Melanoma Cell Line
Gene: Slc35e1 (solute carrier family 35, member E1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: Golgi apparatus, membrane Pathways: UniProt: Q8CD26 Entrez ID: 270066
Does Knockout of Ttc28 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Ttc28
response to virus
Embryonic Fibroblast Cell Line
Gene: Ttc28 (tetratricopeptide repeat domain 28) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, regulation of mitotic cell cycle; CC: centrosome, cytoplasm, cytoskeleton, midbody, mitotic spindle, mitotic spindle midzone, mitotic spindle pole, spindle, spi...
Does Knockout of Fhit in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Fhit
cell proliferation
Mouse kidney carcinoma cell
Gene: Fhit (fragile histidine triad gene) Type: protein-coding Summary: This gene encodes a member of the HIT family of proteins that are characterized by the presence of a histidine triad sequence. The encoded protein is a diadenosine triphosphate hydrolase enzyme that cleaves the P(1)-P(3)-bis(5'-aden...
Does Knockout of Eapp in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Eapp
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Eapp (E2F-associated phosphoprotein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription elongation by RNA polymerase II, positive regulation of cell population proliferation, positive regulation of transcription elongation by RNA po...
Does Knockout of Gm4131 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Gm4131
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Gm4131 (predicted gene 4131) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A0A140LJ24 Entrez ID: 100042960
Does Knockout of Kri1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Kri1
cell proliferation
Embryonic Stem Cell Line
Gene: Kri1 (KRI1 homolog) Type: protein-coding Summary: No summary available. Gene Ontology: CC: 90S preribosome, nucleolus Pathways: UniProt: V9GXJ9, F6WIU1 Entrez ID: 215194
Does Knockout of Lrrc23 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Lrrc23
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Lrrc23 (leucine rich repeat containing 23) Type: protein-coding Summary: Involved in flagellated sperm motility and radial spoke assembly. Located in sperm flagellum. Is active in cytosol. Is expressed in lung; lung epithelium; nasal cavity respiratory epithelium; nasal epithelium; and palatal she...
Does Knockout of Magt1 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Magt1
protein/peptide distribution
myoblast cell line
Gene: Magt1 (magnesium transporter 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cognition, magnesium ion transmembrane transport, magnesium ion transport, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein glycosylation; CC: endop...
Does Knockout of Ndufa3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ndufa3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ndufa3 (NADH:ubiquinone oxidoreductase subunit A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner membrane, mitochondrion, respiratory chain complex I ...
Does Knockout of Rapgef4 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Rapgef4
protein/peptide distribution
myoblast cell line
Gene: Rapgef4 (Rap guanine nucleotide exchange factor (GEF) 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, Ras protein signal transduction, adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenyla...
Does Knockout of Dlgap3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Dlgap3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dlgap3 (DLG associated protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: modification of postsynaptic structure, modulation of chemical synaptic transmission, protein-containing complex assembly, signaling; MF: PDZ domain binding, amyloid-beta binding, mole...
Does Knockout of Ccdc115 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Ccdc115
cell proliferation
Mouse kidney carcinoma cell
Gene: Ccdc115 (coiled-coil domain containing 115) Type: protein-coding Summary: Predicted to enable unfolded protein binding activity. Predicted to be involved in cellular response to increased oxygen levels; intracellular monoatomic cation homeostasis; and lysosomal protein catabolic process. Located i...
Does Knockout of Usp36 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Usp36
cell proliferation
Embryonic Stem Cell Line
Gene: Usp36 (ubiquitin specific peptidase 36) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, negative regulation of macroautophagy, nucleolus organization, protein deubiquitination, protein stabilization, proteolysis, regulat...
Does Knockout of Bet1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Bet1
cell proliferation
Embryonic Stem Cell Line
Gene: Bet1 (Bet1 golgi vesicular membrane trafficking protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endoplasmic reticulum to Golgi vesicle-mediated transport, protein transport, vesicle fusion with Golgi apparatus, vesicle-mediated transport; MF: SNAP receptor ...
Does Knockout of Osbpl9 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Osbpl9
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Osbpl9 (oxysterol binding protein-like 9) Type: protein-coding Summary: No summary available. Gene Ontology: MF: lipid binding, sterol binding; CC: Golgi apparatus, cytosol, endosome, late endosome membrane, membrane Pathways: Bile acid and bile salt metabolism, Metabolism, Metab...
Does Knockout of Brca2 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Brca2
response to virus
Embryonic Fibroblast Cell Line
Gene: Brca2 (breast cancer 2, early onset) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA damage response, signal transduction by p53 class mediator, DNA recombination, DNA repair, brain development, cell population proliferation, cellular respon...
Does Knockout of Zmynd10 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Zmynd10
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Zmynd10 (zinc finger, MYND domain containing 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cilium movement, inner dynein arm assembly, motile cilium assembly, outer dynein arm assembly, positive regulation of motile cilium assembly, protein folding, protein lo...
Does Knockout of Uba5 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Uba5
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Uba5 (ubiquitin-like modifier activating enzyme 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: erythrocyte differentiation, megakaryocyte differentiation, neuromuscular process, protein K69-linked ufmylation, protein ufmylation, regulation of intracellular estro...
Does Knockout of Ndufb11 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Ndufb11
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ndufb11 (NADH:ubiquinone oxidoreductase subunit B11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner membrane, mitochondrion, respiratory chain complex I ...
Does Knockout of Mcm4 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,172
Knockout
Mcm4
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Mcm4 (minichromosome maintenance complex component 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, DNA replication initiation, DNA strand elongation involved in DNA replication, double-strand break repair via break-induced replication, mitotic DN...
Does Knockout of Rab35 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Rab35
cell proliferation
Colonic Cancer Cell Line
Gene: Rab35 (RAB35, member RAS oncogene family) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rab protein signal transduction, antigen processing and presentation, cellular response to nerve growth factor stimulus, endocytic recycling, endosomal transport, intracellular...
Does Knockout of Spop in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Spop
cell proliferation
Embryonic Stem Cell Line
Gene: Spop (speckle-type BTB/POZ protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glucose homeostasis, negative regulation of transcription by RNA polymerase II, positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway, pos...
Does Knockout of Gngt1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Gngt1
cell proliferation
Mouse kidney carcinoma cell
Gene: Gngt1 (guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, cardiac muscle cell apoptotic process, cellular response to hypoxia, eye ph...
Does Knockout of Cox7b in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Cox7b
tumorigenicity
Colonic Cancer Cell Line
Gene: Cox7b (cytochrome c oxidase subunit 7B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: central nervous system development, mitochondrial electron transport, cytochrome c to oxygen, oxidative phosphorylation; CC: membrane, mitochondrial inner membrane, mitochondrial...
Does Knockout of Cyld in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Cyld
cell proliferation
Mouse kidney carcinoma cell
Gene: Cyld (CYLD lysine 63 deubiquitinase) Type: protein-coding Summary: This gene encodes a protein that is a member of the ubiquitin C-terminal hydrolase subfamily of the deubiquitinating enzyme family. Members of this family catalyze the removal of ubiquitin from a substrate or another ubiquitin mole...
Does Knockout of Znhit2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Znhit2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Znhit2 (zinc finger, HIT domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, zinc ion binding Pathways: UniProt: Q9QY66 Entrez ID: 29805
Does Knockout of 5031410I06Rik in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
5031410I06Rik
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: 5031410I06Rik (RIKEN cDNA 5031410I06 gene) Type: protein-coding Summary: RIKEN cDNA 5031410I06 gene Gene Ontology: Pathways: UniProt: E9Q4E0 Entrez ID: 381622
Does Knockout of Ogfr in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Ogfr
cell proliferation
Mouse kidney carcinoma cell
Gene: Ogfr (opioid growth factor receptor) Type: protein-coding Summary: No summary available. Gene Ontology: MF: opioid growth factor receptor activity, signaling receptor activity; CC: cytoplasm, membrane, nucleus Pathways: UniProt: Q99PG2 Entrez ID: 72075
Does Knockout of Arpc2 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Arpc2
cell proliferation
Colonic Cancer Cell Line
Gene: Arpc2 (actin related protein 2/3 complex, subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Arp2/3 complex-mediated actin nucleation, actin filament polymerization, cellular response to epidermal growth factor stimulus, cellular response to platelet-derived...
Does Knockout of Arhgef25 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Arhgef25
response to virus
Embryonic Fibroblast Cell Line
Gene: Arhgef25 (Rho guanine nucleotide exchange factor 25) Type: protein-coding Summary: No summary available. Gene Ontology: MF: guanyl-nucleotide exchange factor activity, protein binding; CC: cytoplasm, extrinsic component of membrane, membrane, myofibril, plasma membrane, sarcomere ...
Does Knockout of Lingo4 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Lingo4
cell proliferation
Colonic Cancer Cell Line
Gene: Lingo4 (leucine rich repeat and Ig domain containing 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of synapse assembly, regulation of nervous system development; MF: molecular_function, signaling receptor activity; CC: membrane, plasma membr...
Does Knockout of Dpcd in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Dpcd
protein/peptide distribution
myoblast cell line
Gene: Dpcd (deleted in primary ciliary dyskinesia) Type: protein-coding Summary: No summary available. Gene Ontology: BP: determination of left/right symmetry, epithelial cilium movement involved in extracellular fluid movement, establishment of localization in cell, flagellated sperm motility,...
Does Knockout of Clec3b in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Clec3b
protein/peptide accumulation
Mouse cell
Gene: Clec3b (C-type lectin domain family 3, member b) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bone mineralization, ossification, positive regulation of plasminogen activation, skeletal system development; MF: calcium ion binding, carbohydrate binding, heparin bin...
Does Knockout of Kcns2 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Kcns2
response to virus
Microglial Cell Line
Gene: Kcns2 (K+ voltage-gated channel, subfamily S, 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: action potential, monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion transmembrane transport, potassium ion transport, protein homooligomeri...
Does Knockout of Sh3tc2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Sh3tc2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sh3tc2 (SH3 domain and tetratricopeptide repeats 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: myelination in peripheral nervous system, peripheral nervous system myelin maintenance, regulation of ERBB signaling pathway, regulation of endocytic recycling, regul...
Does Knockout of Htr2c in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Htr2c
autophagy
Embryonic Fibroblast Cell Line
Gene: Htr2c (5-hydroxytryptamine (serotonin) receptor 2C) Type: protein-coding Summary: Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-...
Does Knockout of Tgif1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Tgif1
cell proliferation
Mouse kidney carcinoma cell
Gene: Tgif1 (TGFB-induced factor homeobox 1) Type: protein-coding Summary: Enables chromatin binding activity. Acts upstream of or within several processes, including negative regulation of retinoic acid receptor signaling pathway; positive regulation of amacrine cell differentiation; and regionalizatio...
Does Knockout of Eva1c in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Eva1c
protein/peptide distribution
myoblast cell line
Gene: Eva1c (eva-1 homolog C) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carbohydrate binding, heparin binding, molecular_function; CC: extracellular region, membrane, plasma membrane Pathways: UniProt: P58659 Entrez ID: 70967
Does Knockout of C1qa in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
C1qa
response to chemicals
Pancreatic Cancer Cell Line
Gene: C1qa (complement component 1, q subcomponent, alpha polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: astrocyte activation, complement activation, classical pathway, complement-mediated synapse pruning, immune system process, innate immune response, micro...
Does Knockout of Rnd1 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Rnd1
protein/peptide distribution
Microglial Cell Line
Gene: Rnd1 (Rho family GTPase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament organization, negative regulation of cell adhesion, neuron remodeling, regulation of actin cytoskeleton organization, signal transduction, small GTPase-mediated signal transduc...
Does Knockout of Rpap3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Rpap3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Rpap3 (RNA polymerase II associated protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: CC: R2TP complex, RPAP3/R2TP/prefoldin-like complex, ciliary basal body, cilium, cytosol, protein folding chaperone complex Pathways: UniProt: Q9D706 ...
Does Knockout of Cpsf1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Cpsf1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Cpsf1 (cleavage and polyadenylation specific factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA 3'-end processing, mRNA processing; MF: RNA binding, enzyme binding, mRNA 3'-UTR AU-rich region binding, nucleic acid binding; CC: mRNA cleavage and polyadenyl...
Does Knockout of Gphb5 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Gphb5
protein/peptide accumulation
Mouse cell
Gene: Gphb5 (glycoprotein hormone beta 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, regulation of thyroid hormone receptor signaling pathway; MF:...
Does Knockout of Slc2a9 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Slc2a9
cell proliferation
Regulatory T cell
Gene: Slc2a9 (solute carrier family 2 (facilitated glucose transporter), member 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-glucose import, D-glucose transmembrane transport, dehydroascorbic acid transport, fructose transmembrane transport, transmembrane transpor...
Does Knockout of Map3k4 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Map3k4
protein/peptide distribution
myoblast cell line
Gene: Map3k4 (mitogen-activated protein kinase kinase kinase 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, chorionic trophoblast cell differentiation, determination of dorsal identity, intracellular signal transduction, male germ-line sex determination,...
Does Knockout of Cacna2d1 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Cacna2d1
response to virus
Microglial Cell Line
Gene: Cacna2d1 (calcium channel, voltage-dependent, alpha2/delta subunit 1) Type: protein-coding Summary: This gene encodes a regulatory component of the voltage-dependent calcium channel complex. The product of this gene is a proprotein that is proteolytically processed into alpha-2 and delta subunits,...
Does Knockout of Fkrp in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Fkrp
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Fkrp (fukutin related protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adult walking behavior, basement membrane organization, bone mineralization, brain development, camera-type eye development, central nervous system development, connective tissue developm...
Does Knockout of Stx3 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Stx3
autophagy
Embryonic Fibroblast Cell Line
Gene: Stx3 (syntaxin 3) Type: protein-coding Summary: Predicted to enable SNAP receptor activity; SNARE binding activity; and arachidonate binding activity. Involved in exocytic insertion of neurotransmitter receptor to postsynaptic membrane; modulation of chemical synaptic transmission; and vesicle-med...
Does Knockout of Gm20791 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Gm20791
phagocytosis
macrophage
Gene: Gm20791 (Y-linked testis-specific protein 1-like) Type: pseudo Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 108168617
Does Knockout of Numbl in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Numbl
cell proliferation
Mouse kidney carcinoma cell
Gene: Numbl (numb-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adherens junction organization, axonogenesis, cytokine-mediated signaling pathway, forebrain development, lateral ventricle development, nervous system development, neuroblast division in subventricul...
Does Knockout of Atad3a in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Atad3a
cell proliferation
Mouse kidney carcinoma cell
Gene: Atad3a (ATPase family, AAA domain containing 3A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, HRI-mediated signaling, PERK-mediated unfolded protein response, antiviral innate immune response, mitochondrion organization, negative regulation o...
Does Knockout of G6pd2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
G6pd2
cell viability
Immortal mouse chromaffin cells
Gene: G6pd2 (glucose-6-phosphate dehydrogenase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NADP+ metabolic process, NADPH regeneration, cellular response to oxidative stress, cholesterol biosynthetic process, erythrocyte maturation, glucose 6-phosphate metabolic pr...
Does Knockout of Ankrd23 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Ankrd23
cell cycle progression
breast epithelium
Gene: Ankrd23 (ankyrin repeat domain 23) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid metabolic process, positive regulation of transcription by RNA polymerase II, regulation of sarcomere organization, response to mechanical stimulus, response to muscle stre...
Does Knockout of Cdkl1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Cdkl1
protein/peptide accumulation
Regulatory T cell
Gene: Cdkl1 (cyclin dependent kinase like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: heart development, regulation of cell cycle, regulation of cilium assembly; MF: ATP binding, cyclin-dependent protein serine/threonine kinase activity, kinase activity, nucleotide...
Does Knockout of Cep170 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Cep170
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cep170 (centrosomal protein 170) Type: protein-coding Summary: No summary available. Gene Ontology: MF: molecular_function, protein binding; CC: centriolar subdistal appendage, centriole, centrosome, ciliary basal body, cytoplasm, cytoskeleton, cytosol, microtubule, spindle Pathw...
Does Knockout of Larp4 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Larp4
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Larp4 (La ribonucleoprotein 4) Type: protein-coding Summary: Predicted to enable mRNA 3'-UTR binding activity and poly(A) binding activity. Predicted to be involved in cytoskeleton organization; positive regulation of translation; and regulation of cell morphogenesis. Predicted to be part of cytos...
Does Knockout of Cldn24 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Cldn24
cell proliferation
Mouse kidney carcinoma cell
Gene: Cldn24 (claudin 24) Type: protein-coding Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the para...
Does Knockout of Gjd4 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Gjd4
cell cycle progression
breast epithelium
Gene: Gjd4 (gap junction protein, delta 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell communication, cell-cell signaling, regulation of satellite cell activation involved in skeletal muscle regeneration, transmembrane transport; CC: anchoring junction, connexin ...
Does Knockout of Tmem147 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Tmem147
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tmem147 (transmembrane protein 147) Type: protein-coding Summary: Predicted to enable ribosome binding activity. Predicted to be involved in multi-pass transmembrane protein insertion into ER membrane and protein localization to nuclear inner membrane. Predicted to be located in nuclear membrane a...
Does Knockout of Ssxb5 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Ssxb5
protein/peptide distribution
myoblast cell line
Gene: Ssxb5 (SSX member B5) Type: protein-coding Summary: Predicted to be located in sperm flagellum. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in X-linked spermatogenic failure 5 and synovial sarcoma. Orthologous to several human genes including SSX1 (SSX family membe...
Does Knockout of Creld2 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Creld2
protein/peptide distribution
myoblast cell line
Gene: Creld2 (cysteine-rich with EGF-like domains 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: calcium ion binding, extracellular matrix structural constituent, isomerase activity, molecular_function, protein disulfide isomerase activity; CC: Golgi apparatus, endopl...
Does Knockout of Gnb1l in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Gnb1l
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Gnb1l (guanine nucleotide binding protein (G protein), beta polypeptide 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage checkpoint signaling, DNA damage response, social behavior; CC: cytoplasm, nucleus Pathways: UniProt: Q9EQ15...
Does Knockout of Rho in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Rho
protein/peptide distribution
myoblast cell line
Gene: Rho (rhodopsin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled opsin signaling pathway, G protein-coupled receptor signaling pathway, absorption of visible light, cellular response to light stimulus, detection of light stimulus, detection of tempe...
Does Knockout of Eloa in Pancreatic Cell Line causally result in cell proliferation?
1
2,192
Knockout
Eloa
cell proliferation
Pancreatic Cell Line
Gene: Eloa (elongin A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II, transcription by RNA polymerase II, transcription elongation by RNA polymerase II, transcription initiation ...