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Does Knockout of Tshb in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Tshb
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Tshb (thyroid stimulating hormone, beta subunit) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, extracellular region, extracellular space Pathways: Autoimmune thyroid disease - Mus musculus (mouse), Neuroactive ligand-receptor interaction - Mus ...
Does Knockout of Dqx1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Dqx1
protein/peptide accumulation
Embryonic Cell Line
Gene: Dqx1 (DEAQ RNA-dependent ATPase) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, ATP hydrolysis activity, RNA binding, helicase activity, nucleotide binding; CC: nucleus, spliceosomal complex Pathways: UniProt: Q924H9 Entrez I...
Does Knockout of Hmgxb3 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Hmgxb3
protein/peptide distribution
myoblast cell line
Gene: Hmgxb3 (HMG box domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, molecular_function; CC: cellular_component, nucleus Pathways: UniProt: Q6NZP6, Q6AXF8, G3X9M3, Q8R168, Q8BY57, Q9JJ64, Q6PEF4, A0A494B973, A0A494B9M0...
Does Knockout of Eif3d in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Eif3d
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Eif3d (eukaryotic translation initiation factor 3, subunit D) Type: protein-coding Summary: No summary available. Gene Ontology: BP: IRES-dependent viral translational initiation, cap-dependent translational initiation, cytoplasmic translational initiation, formation of cytoplasmic transl...
Does Knockout of Dek in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Dek
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dek (DEK proto-oncogene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, positive regulation of transcription by RNA polymerase I, positive regulation of transcription by RNA polymerase II, positive regulation of transcr...
Does Knockout of Emp2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Emp2
cell proliferation
Mouse kidney carcinoma cell
Gene: Emp2 (epithelial membrane protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell mediated cytotoxicity, actin filament organization, actin-mediated cell contraction, apoptotic process, bleb assembly, blood vessel endothelial cell migration, caveola assemb...
Does Knockout of Pdcl in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Pdcl
cell proliferation
Melanoma Cell Line
Gene: Pdcl (phosducin-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, heterotrimeric G-protein complex assembly, negative regulation of protein refolding, positive regulation of smoothened signaling pathway, protein folding, regulation ...
Does Knockout of Zcchc24 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Zcchc24
cell proliferation
Melanoma Cell Line
Gene: Zcchc24 (zinc finger, CCHC domain containing 24) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, nucleic acid binding, zinc ion binding Pathways: UniProt: B2RVL6 Entrez ID: 71918
Does Knockout of Crlf2 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Crlf2
cell proliferation
Melanoma Cell Line
Gene: Crlf2 (cytokine receptor-like factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytokine-mediated signaling pathway, inflammatory response, positive regulation of cell population proliferation, positive regulation of interleukin-5 production, positive regula...
Does Knockout of Spag4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Spag4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Spag4 (sperm associated antigen 4) Type: protein-coding Summary: Predicted to enable identical protein binding activity and protein-membrane adaptor activity. Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be located in microtubule. Predicted to be part of meiot...
Does Knockout of Dusp28 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Dusp28
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Dusp28 (dual specificity phosphatase 28) Type: protein-coding Summary: Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Orthologous to human DUSP28 (dual specificity phosphatase 28). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology...
Does Knockout of Enpp1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Enpp1
cell proliferation
Embryonic Stem Cell Line
Gene: Enpp1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) Type: protein-coding Summary: This gene encodes a member of the nucleoside pyrophosphatase/phosphodiesterase family of enzymes that catalyzes the hydrolysis of pyrophosphate and phosphodiester bonds in nucleotide triphosphates and oligonuc...
Does Knockout of Sipa1l2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Sipa1l2
cell proliferation
Colonic Cancer Cell Line
Gene: Sipa1l2 (signal-induced proliferation-associated 1 like 2) Type: protein-coding Summary: Predicted to enable GTPase activator activity. Involved in presynaptic signal transduction. Is active in glutamatergic synapse. Is expressed in brain and thymus primordium. Orthologous to human SIPA1L2 (signal...
Does Knockout of Eif3f in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Eif3f
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Eif3f (eukaryotic translation initiation factor 3, subunit F) Type: protein-coding Summary: Enables cysteine-type deubiquitinase activity and translation initiation factor binding activity. Contributes to translation initiation factor activity. Involved in translational initiation. Part of eukaryo...
Does Knockout of Coq9 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Coq9
cell cycle progression
breast epithelium
Gene: Coq9 (coenzyme Q9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial electron transport, NADH to ubiquinone, ubiquinone biosynthetic process; MF: enzyme activator activity, isoprenoid binding, lipid binding, protein homodimerization activity; CC: mitocho...
Does Knockout of Chd8 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Chd8
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Chd8 (chromodomain helicase DNA binding protein 8) Type: protein-coding Summary: This gene encodes a member of the chromodomain-helicase-DNA binding protein family, which is characterized by a SNF2-like domain and two chromatin organization modifier domains. The encoded protein also contains brahm...
Does Knockout of Fxn in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Fxn
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Fxn (frataxin) Type: protein-coding Summary: Predicted to enable several functions, including 2 iron, 2 sulfur cluster binding activity; ferroxidase activity; and iron ion binding activity. Involved in [4Fe-4S] cluster assembly. Acts upstream of or within several processes, including adult walking...
Does Knockout of Efcab6 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Efcab6
protein/peptide distribution
myoblast cell line
Gene: Efcab6 (EF-hand calcium binding domain 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, flagellated sperm motility; MF: calcium ion binding, metal ion binding, molecular_function; CC: axonemal A tubule inner sheath, cell projection, cilium, cyt...
Does Knockout of Pnpla5 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Pnpla5
protein/peptide distribution
myoblast cell line
Gene: Pnpla5 (patatin-like phospholipase domain containing 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid catabolic process, lipid homeostasis, lipid metabolic process, triglyceride catabolic process; MF: hydrolase activity, triacylglycerol lipase activity; CC: ...
Does Knockout of Fbxo43 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Fbxo43
protein/peptide distribution
myoblast cell line
Gene: Fbxo43 (F-box protein 43) Type: protein-coding Summary: No summary available. Gene Ontology: BP: meiotic cell cycle, meiotic nuclear division, negative regulation of cell cycle process, negative regulation of meiotic nuclear division, negative regulation of protein catabolic process, prot...
Does Knockout of Milr1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Milr1
protein/peptide accumulation
Regulatory T cell
Gene: Milr1 (mast cell immunoglobulin like receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mast cell degranulation, negative regulation of mast cell activation; CC: extracellular region, membrane, plasma membrane Pathways: UniProt: Q3TB92 ...
Does Knockout of Rbm7 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Rbm7
cell proliferation
Melanoma Cell Line
Gene: Rbm7 (RNA binding motif protein 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: meiotic cell cycle, regulation of alternative mRNA splicing, via spliceosome, snRNA catabolic process; MF: 14-3-3 protein binding, RNA binding, nucleic acid binding, pre-mRNA intronic...
Does Knockout of Vamp2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Vamp2
protein/peptide accumulation
Embryonic Cell Line
Gene: Vamp2 (vesicle-associated membrane protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to plasma membrane protein transport, SNARE complex assembly, calcium-ion regulated exocytosis, cellular response to insulin stimulus, eosinophil degranulation, estab...
Does Knockout of Tmem115 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Tmem115
cell cycle progression
breast epithelium
Gene: Tmem115 (transmembrane protein 115) Type: protein-coding Summary: No summary available. Gene Ontology: BP: retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; MF: identical protein binding; CC: Golgi apparatus, Golgi cisterna membrane, Golgi transport complex, membrane,...
Does Knockout of Cblc in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Cblc
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cblc (Casitas B-lineage lymphoma c) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway, negative regulation of MAPK cascade, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of neuron...
Does Knockout of Npm1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Npm1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Npm1 (nucleophosmin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair, cell volume homeostasis, cellular response to UV, cellular senescence, centrosome cycle, chromatin remodeling, cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA tra...
Does Knockout of Mir7240 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Mir7240
cell cycle progression
breast epithelium
Gene: Mir7240 (microRNA 7240) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Ermard in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Ermard
protein/peptide distribution
myoblast cell line
Gene: Ermard (ER membrane associated RNA degradation) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8C9C8, E9Q048, A0A2I3BPX2, A0A2I3BQD2, A0A2I3BPT5, A0A2I3BQP4, A0A2I3BQS2, A0A2I3BQQ1 Entrez ID: 381062
Does Knockout of Kcna1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Kcna1
autophagy
Embryonic Fibroblast Cell Line
Gene: Kcna1 (potassium voltage-gated channel, shaker-related subfamily, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: action potential, brain development, cell communication by electrical coupling, cellular response to magnesium ion, detection of mechanical st...
Does Knockout of Gm13040 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Gm13040
cell proliferation
Embryonic Stem Cell Line
Gene: Gm13040 (predicted gene 13040) Type: protein-coding Summary: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul2-RING ubiquitin ligase complex. Predicted to...
Does Knockout of Gm21927 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Gm21927
protein/peptide distribution
Microglial Cell Line
Gene: Gm21927 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 pseudogene) Type: pseudo Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 100417844
Does Knockout of Bag6 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Bag6
protein/peptide distribution
myoblast cell line
Gene: Bag6 (BCL2-associated athanogene 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, NK T cell activation, antigen processing and presentation of peptide antigen via MHC class I, apoptotic process, brain development, cell differentiation, chromatin orga...
Does Knockout of Mkrn2os in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Mkrn2os
cell proliferation
Mouse kidney carcinoma cell
Gene: Mkrn2os (makorin, ring finger protein 2, opposite strand) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: D3YX48, D3Z393 Entrez ID: 70291
Does Knockout of Htr2b in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Htr2b
protein/peptide distribution
Microglial Cell Line
Gene: Htr2b (5-hydroxytryptamine (serotonin) receptor 2B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERK1 and ERK2 cascade, G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, G pr...
Does Knockout of Mex3c in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Mex3c
protein/peptide distribution
myoblast cell line
Gene: Mex3c (mex3 RNA binding family member C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chondrocyte hypertrophy, energy homeostasis, regulation of fat cell differentiation; MF: RNA binding, metal ion binding, nucleic acid binding, transferase activity, ubiquitin pr...
Does Knockout of Prelid2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Prelid2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Prelid2 (PRELI domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intermembrane lipid transfer, phospholipid transport; CC: mitochondrial intermembrane space, mitochondrion Pathways: UniProt: Q0VBB0 Entrez ID: 77619
Does Knockout of Itln1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Itln1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Itln1 (intelectin 1 (galactofuranose binding)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of D-glucose import, positive regulation of protein phosphorylation, response to nematode; MF: calcium ion binding, carbohydrate binding, identical pro...
Does Knockout of Racgap1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,172
Knockout
Racgap1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Racgap1 (Rac GTPase-activating protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rho protein signal transduction, actomyosin contractile ring assembly, cell differentiation, cell division, erythrocyte differentiation, mitotic cytokinesis, mitotic spindle mi...
Does Knockout of Med1 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Med1
protein/peptide distribution
myoblast cell line
Gene: Med1 (mediator complex subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, androgen biosynthetic process, angiogenesis, animal organ morphogenesis, animal organ regeneration, brain development, camera-type eye...
Does Knockout of Cda in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Cda
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cda (cytidine deaminase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CMP catabolic process, UMP salvage, carbohydrate derivative metabolic process, cellular response to external biotic stimulus, dCMP catabolic process, nucleobase-containing small molecule metabo...
Does Knockout of Cenpu in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Cenpu
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cenpu (centromere protein U) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chordate embryonic development, chromosome segregation; CC: centriolar satellite, chromosome, chromosome, centromeric region, cytoplasm, inner kinetochore, kinetochore, nucleoplasm, nucleus...
Does Knockout of Fam110c in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Fam110c
response to virus
Embryonic Fibroblast Cell Line
Gene: Fam110c (family with sequence similarity 110, member C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of cell migration, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, regulation of cell projection as...
Does Knockout of Sv2b in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Sv2b
tumorigenicity
Colonic Cancer Cell Line
Gene: Sv2b (synaptic vesicle glycoprotein 2b) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chemical synaptic transmission, neurotransmitter transport, regulation of presynaptic cytosolic calcium ion concentration, regulation of synaptic vesicle exocytosis, transmembran...
Does Knockout of Irx6 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Irx6
cell viability
Immortal mouse chromaffin cells
Gene: Irx6 (Iroquois homeobox 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, cell development, detection of visible light, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, neuron d...
Does Knockout of Lsm1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Lsm1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Lsm1 (LSM1 homolog, mRNA degradation associated) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, deadenylation-dependent decapping of nuclear-transcribed mRNA, histone mRNA catabolic process, mRNA processing, negative regulation of neuron differentiati...
Does Knockout of Scube1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Scube1
cell proliferation
Mouse kidney carcinoma cell
Gene: Scube1 (signal peptide, CUB domain, EGF-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of smoothened signaling pathway, signal transduction; MF: calcium ion binding, identical protein binding, protein binding; CC: cell surface, external ...
Does Knockout of Rplp1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Rplp1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rplp1 (ribosomal protein lateral stalk subunit P1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, regulation of translation, translational elongation; MF: protein kinase activator activity, ribonucleoprotein complex binding, structural cons...
Does Knockout of Opa1 in Melanoma Cell Line causally result in cell proliferation?
1
2,492
Knockout
Opa1
cell proliferation
Melanoma Cell Line
Gene: Opa1 (OPA1, mitochondrial dynamin like GTPase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GTP metabolic process, apoptotic process, calcium import into the mitochondrion, cellular senescence, cristae formation, inner mitochondrial membrane organization, intrace...
Does Knockout of Lsm6 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Lsm6
protein/peptide accumulation
Regulatory T cell
Gene: Lsm6 (LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA catabolic process, mRNA processing, mRNA splicing, via spliceosome, maturation of SSU-rRNA, rRNA processing, tRNA processing;...
Does Knockout of Trim62 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Trim62
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Trim62 (tripartite motif-containing 62) Type: protein-coding Summary: No summary available. Gene Ontology: BP: immune system process, innate immune response, negative regulation of epithelial to mesenchymal transition, negative regulation of viral transcription, positive regulation of DNA...
Does Knockout of Fnbp4 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Fnbp4
protein/peptide accumulation
Embryonic Cell Line
Gene: Fnbp4 (formin binding protein 4) Type: protein-coding Summary: Predicted to be located in nucleoplasm. Is expressed in endolymphatic appendage and otocyst. Orthologous to human FNBP4 (formin binding protein 4). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: ...
Does Knockout of Sfr1 in Lymphoma Cell Line causally result in response to chemicals?
0
1,558
Knockout
Sfr1
response to chemicals
Lymphoma Cell Line
Gene: Sfr1 (SWI5 dependent recombination repair 1) Type: protein-coding Summary: Predicted to enable transcription coactivator activity. Involved in double-strand break repair via homologous recombination. Located in nucleus. Part of Swi5-Sfr1 complex. Is expressed in olfactory cortex ventricular layer;...
Does Knockout of Gdf5 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Gdf5
protein/peptide distribution
myoblast cell line
Gene: Gdf5 (growth differentiation factor 5) Type: protein-coding Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcript...
Does Knockout of Abca6 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Abca6
protein/peptide distribution
myoblast cell line
Gene: Abca6 (ATP-binding cassette, sub-family A member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid transport, transmembrane transport; MF: ABC-type transporter activity, ATP binding, ATP hydrolysis activity, ATPase-coupled transmembrane transporter activity, ...
Does Knockout of Pik3ca in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Pik3ca
cell proliferation
Mouse kidney carcinoma cell
Gene: Pik3ca (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: TORC2 signaling, actin cytoskeleton organization, adipose tissue development, angiogenesis, autosome genomic imprinting, cardiac muscle ce...
Does Knockout of Mkrn2 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,286
Knockout
Mkrn2
cell proliferation
Mouse kidney carcinoma cell
Gene: Mkrn2 (makorin, ring finger protein, 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, cell differentiation, negative regulation of inflammatory response to antigenic stimulus, negative regulation of non-canonical NF-kappaB signal trans...
Does Knockout of Ptbp1 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Ptbp1
response to virus
Microglial Cell Line
Gene: Ptbp1 (polypyrimidine tract binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: IRES-dependent viral translational initiation, RNA splicing, gene expression, mRNA processing, negative regulation of RNA splicing, negative regulation of gene expression,...
Does Knockout of Tceanc2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Tceanc2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Tceanc2 (transcription elongation factor A (SII) N-terminal and central domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, regulation of transcription by RNA polymerase II; CC: nucleus Pathways: UniPr...
Does Knockout of Pcdhga6 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Pcdhga6
cell proliferation
Mouse kidney carcinoma cell
Gene: Pcdhga6 (protocadherin gamma subfamily A, 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding, molecular_function; CC: membrane, pl...
Does Knockout of Tinf2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Tinf2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tinf2 (Terf1 (TRF1)-interacting nuclear factor 2) Type: protein-coding Summary: Enables telomeric DNA binding activity. Acts upstream of or within negative regulation of telomere maintenance. Located in chromosome, telomeric region. Is expressed in several structures, including genitourinary syste...
Does Knockout of Plp2 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Plp2
protein/peptide accumulation
Embryonic Cell Line
Gene: Plp2 (proteolipid protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: chemokine binding; CC: membrane, plasma membrane Pathways: UniProt: Q9R1Q7 Entrez ID: 18824
Does Knockout of Cdkn2aipnl in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Cdkn2aipnl
cell cycle progression
breast epithelium
Gene: Cdkn2aipnl (CDKN2A interacting protein N-terminal like) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9D211 Entrez ID: 52626
Does Knockout of Car2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Car2
cell proliferation
Mouse kidney carcinoma cell
Gene: Car2 (carbonic anhydrase 2) Type: protein-coding Summary: Enables carbonate dehydratase activity. Involved in positive regulation of dipeptide transmembrane transport and regulation of intracellular pH. Acts upstream of or within several processes, including positive regulation of GABAergic synapt...
Does Knockout of Arx in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Arx
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Arx (aristaless related homeobox) Type: protein-coding Summary: This gene encodes a transcription factor that plays an important role in the development of forebrain. Male mice lacking this gene have smaller brains, olfactory bulbs and testes, and die within half a day after birth. Mice lacking th...
Does Knockout of Cass4 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Cass4
protein/peptide accumulation
Embryonic Cell Line
Gene: Cass4 (Cas scaffolding protein family member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell migration, cell surface receptor protein tyrosine kinase signaling pathway, positive regulation of cell migration, positive regulation of phosphatidyl...
Does Knockout of Ppp1r12b in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Ppp1r12b
cell proliferation
Regulatory T cell
Gene: Ppp1r12b (protein phosphatase 1, regulatory subunit 12B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: neuron projection morphogenesis, signal transduction; MF: enzyme inhibitor activity, myosin phosphatase regulator activity, phosphatase regulator activity, prote...
Does Knockout of Prkab1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Prkab1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Prkab1 (protein kinase, AMP-activated, beta 1 non-catalytic subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to nutrient levels, fatty acid biosynthetic process, fatty acid metabolic process, lipid metabolic process, nail development, posit...
Does Knockout of Stk11 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Stk11
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Stk11 (serine/threonine kinase 11) Type: protein-coding Summary: This gene encodes a member of the serine/threonine kinase family. The encoded protein, a known tumor suppressor, activates (via phosphorylation) adenine monophosphate-activated protein kinase (AMPK) and AMPK-related kinase proteins. ...
Does Knockout of Med17 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Med17
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Med17 (mediator complex subunit 17) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, positive regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II, positive regulation o...
Does Knockout of Supt4a in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Supt4a
protein/peptide distribution
myoblast cell line
Gene: Supt4a (SPT4A, DSIF elongation factor subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, elongation, negative regulation of transcription by RNA polymerase II, negative regulation of transcription elongation ...
Does Knockout of Lonp1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
1,130
Knockout
Lonp1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Lonp1 (lon peptidase 1, mitochondrial) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to oxidative stress, chaperone-mediated protein complex assembly, mitochondrial protein catabolic process, mitochondrion organization, negative regulation of ins...
Does Knockout of Dmkn in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Dmkn
cell proliferation
Mouse kidney carcinoma cell
Gene: Dmkn (dermokine) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cornified envelope assembly; CC: extracellular region, extracellular space Pathways: UniProt: Q6P253 Entrez ID: 73712
Does Knockout of Ranbp2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Ranbp2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ranbp2 (RAN binding protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NLS-bearing protein import into nucleus, centrosome localization, cytoplasmic pattern recognition receptor signaling pathway, intracellular glucose homeostasis, mRNA transport, negative r...
Does Knockout of Mtdh in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Mtdh
protein/peptide accumulation
Embryonic Cell Line
Gene: Mtdh (metadherin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipopolysaccharide-mediated signaling pathway, negative regulation of apoptotic process, negative regulation of transcription by RNA polymerase II, positive regulation of DNA-templated transcription, ...
Does Knockout of Stac3 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Stac3
phagocytosis
macrophage
Gene: Stac3 (SH3 and cysteine rich domain 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: neuromuscular synaptic transmission, positive regulation of protein localization to plasma membrane, positive regulation of voltage-gated calcium channel activity, skeletal muscle...
Does Knockout of Rdh5 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Rdh5
cell proliferation
Embryonic Stem Cell Line
Gene: Rdh5 (retinol dehydrogenase 5) Type: protein-coding Summary: Enables all-trans-retinol dehydrogenase (NAD+) activity. Involved in retinoid metabolic process. Located in endoplasmic reticulum lumen. Is expressed in several structures, including aorta-gonad-mesonephros; central nervous system; embry...
Does Knockout of Senp6 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Senp6
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Senp6 (SUMO/sentrin specific peptidase 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein desumoylation, protein modification by small protein removal, protein sumoylation, proteolysis, regulation of kinetochore assembly, regulation of spindle assembly; MF: ...
Does Knockout of Mtor in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Mtor
cell proliferation
Embryonic Stem Cell Line
Gene: Mtor (mechanistic target of rapamycin kinase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 'de novo' pyrimidine nucleobase biosynthetic process, DNA damage response, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, T-helper 1 cell lineage ...
Does Knockout of Tardbp in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Tardbp
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tardbp (TAR DNA binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 3'-UTR-mediated mRNA destabilization, 3'-UTR-mediated mRNA stabilization, RNA splicing, amyloid fibril formation, gene expression, host-mediated suppression of viral transcription, mRNA...
Does Knockout of Fgf8 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Fgf8
protein/peptide distribution
myoblast cell line
Gene: Fgf8 (fibroblast growth factor 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, aorta morphogenesis, blood vessel remodeling, bone development, branching involved in blood vessel morphogenesis, branching involved in salivary gland morphogenesis, bran...
Does Knockout of Gps2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Gps2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Gps2 (G protein pathway suppressor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, negative regulation of B cell receptor signaling pathway, negative regulation of JNK cascade, negative regulation of fat cell differentiation, negative regu...
Does Knockout of Synpo2 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Synpo2
response to virus
Embryonic Fibroblast Cell Line
Gene: Synpo2 (synaptopodin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, chaperone-mediated autophagy, positive regulation of actin filament bundle assembly, positive regulation of cell migration; MF: 14-3-3 protein binding, actin binding, alp...
Does Knockout of Rspry1 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Rspry1
protein/peptide distribution
myoblast cell line
Gene: Rspry1 (ring finger and SPRY domain containing 1) Type: protein-coding Summary: Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular region. Predicted to be active in cyto...
Does Knockout of Ecd in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Ecd
response to virus
Microglial Cell Line
Gene: Ecd (ecdysoneless cell cycle regulator) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, fibroblast proliferation, mRNA processing, positive regulation of transcription by RNA polymerase II, regulation of G1/S transition of mitotic cell cycle; MF: histo...
Does Knockout of Naxd in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Naxd
cell proliferation
Embryonic Stem Cell Line
Gene: Naxd (NAD(P)HX dehydratase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: metabolite repair, nicotinamide nucleotide metabolic process; MF: ATP binding, ATP-dependent NAD(P)H-hydrate dehydratase activity, hydro-lyase activity, lyase activity, nucleotide binding; C...
Does Knockout of Nek10 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Nek10
response to virus
Embryonic Fibroblast Cell Line
Gene: Nek10 (NIMA (never in mitosis gene a)- related kinase 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mucociliary clearance, regulation of ERK1 and ERK2 cascade, regulation of cell cycle G2/M phase transition; MF: ATP binding, kinase activity, metal ion binding,...
Does Knockout of Tmem74b in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Tmem74b
cell proliferation
Embryonic Stem Cell Line
Gene: Tmem74b (transmembrane protein 74B) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: A2AU34 Entrez ID: 108832
Does Knockout of Trim33 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Trim33
protein/peptide distribution
myoblast cell line
Gene: Trim33 (tripartite motif-containing 33) Type: protein-coding Summary: No summary available. Gene Ontology: BP: gene expression, negative regulation of BMP signaling pathway, protein ubiquitination, regulation of transforming growth factor beta receptor signaling pathway; MF: DNA binding, ...
Does Knockout of Slc25a18 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Slc25a18
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Slc25a18 (solute carrier family 25 (mitochondrial carrier), member 18) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-aspartate transmembrane transport, L-glutamate transmembrane transport, aspartate transmembrane transport, malate-aspartate shuttle, proton trans...
Does Knockout of Lrrtm3 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Lrrtm3
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Lrrtm3 (leucine rich repeat transmembrane neuronal 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of amyloid-beta formation, positive regulation of synapse assembly, regulation of presynapse assembly; CC: glutamatergic synapse, membrane, plas...
Does Knockout of Slc25a1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,286
Knockout
Slc25a1
cell proliferation
Mouse kidney carcinoma cell
Gene: Slc25a1 (solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial citrate transmembrane transport, negative regulation of ferroptosis, transmembrane transport; MF: antiporter activ...
Does Knockout of Prelid1 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Prelid1
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Prelid1 (PRELI domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, intermembrane lipid transfer, lipid transport, negative regulation of apoptotic process, negative regulation of mitochondrial membrane potential, negative regulati...
Does Knockout of Clint1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Clint1
cell proliferation
Colonic Cancer Cell Line
Gene: Clint1 (clathrin interactor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: clathrin coat assembly, endocytosis; MF: clathrin binding, lipid binding, phospholipid binding; CC: Golgi apparatus, clathrin vesicle coat, clathrin-coated vesicle, cytoplasm, cytoplasmic...
Does Knockout of Alg6 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Alg6
cell proliferation
Melanoma Cell Line
Gene: Alg6 (ALG6 alpha-1,3-glucosyltransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: dolichol-linked oligosaccharide biosynthetic process, protein N-linked glycosylation, protein glycosylation; MF: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferas...
Does Knockout of Inpp5a in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Inpp5a
protein/peptide distribution
myoblast cell line
Gene: Inpp5a (inositol polyphosphate-5-phosphatase A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: inositol phosphate metabolic process, negative regulation of calcium-mediated signaling, negative regulation of phospholipase C-activating G protein-coupled receptor sign...
Does Knockout of Nubp2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Nubp2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Nubp2 (nucleotide binding protein 2) Type: protein-coding Summary: Predicted to enable iron-sulfur cluster binding activity. Predicted to be involved in iron-sulfur cluster assembly. Located in nucleus and spindle pole centrosome. Is expressed in several structures, including extraembryonic compon...
Does Knockout of Nifk in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Nifk
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nifk (nucleolar protein interacting with the FHA domain of MKI67) Type: protein-coding Summary: No summary available. Gene Ontology: MF: RNA binding, nucleic acid binding; CC: chromosome, condensed nuclear chromosome, cytoplasm, nucleolus, nucleoplasm, nucleus Pathways: ...
Does Knockout of Csnk1a1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Csnk1a1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Csnk1a1 (casein kinase 1, alpha 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, NLRP3 inflammasome complex assembly, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, TORC1 signaling, Wnt signaling pathway, autophagosome...
Does Knockout of Tpd52 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Tpd52
cell proliferation
Regulatory T cell
Gene: Tpd52 (tumor protein D52) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, positive regulation of cell population proliferation; MF: calcium ion binding, identical protein binding, protein binding, protein homodimerization activity; CC: cytopl...
Does Knockout of Igkv5-43 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
1,130
Knockout
Igkv5-43
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Igkv5-43 (immunoglobulin kappa chain variable 5-43) Type: other Summary: No summary available. Gene Ontology: BP: adaptive immune response, immune response, immune system process; CC: extracellular region, immunoglobulin complex, plasma membrane Pathways: UniProt: ...