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Does Knockout of Limk1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Limk1
autophagy
Embryonic Fibroblast Cell Line
Gene: Limk1 (LIM domain kinase 1) Type: protein-coding Summary: This gene encodes a member of the LIM kinase family of proteins. This protein is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin. This protein also stimu...
Does Knockout of Gsta2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Gsta2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gsta2 (glutathione S-transferase, alpha 2 (Yc2)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glutathione metabolic process, response to bacterium, response to stilbenoid, xenobiotic metabolic process; MF: dinitrosyl-iron complex binding, fatty acid binding, glut...
Does Knockout of Plscr2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Plscr2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Plscr2 (phospholipid scramblase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to lipopolysaccharide, immune response, phosphatidylserine exposure on apoptotic cell surface, plasma membrane phospholipid scrambling, regulation of Fc receptor med...
Does Knockout of Tsacc in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Tsacc
protein/peptide accumulation
Embryonic Cell Line
Gene: Tsacc (TSSK6 activating co-chaperone) Type: protein-coding Summary: Predicted to enable Hsp70 protein binding activity; protein kinase binding activity; and protein kinase inhibitor activity. Predicted to act upstream of or within positive regulation of protein kinase activity. Located in cytoplas...
Does Knockout of Cdc25c in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Cdc25c
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cdc25c (cell division cycle 25C) Type: protein-coding Summary: This gene encodes a dual specificity phosphatase that dephosphorylates cyclin B-bound Cdk1 to trigger entry into mitosis. [provided by RefSeq, Dec 2014]. Gene Ontology: BP: G2/M transition of mitotic cell cycle, cell division,...
Does Knockout of Fnta in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Fnta
response to virus
Embryonic Fibroblast Cell Line
Gene: Fnta (farnesyltransferase, CAAX box, alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: enzyme-linked receptor protein signaling pathway, negative regulation of apoptotic process, nuclear envelope organization, peptide pheromone maturation, positive regulation o...
Does Knockout of Saa1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Saa1
autophagy
Embryonic Fibroblast Cell Line
Gene: Saa1 (serum amyloid A 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acute-phase response, cholesterol metabolic process, response to bacterium; MF: G protein-coupled receptor binding, heparin binding, protein binding; CC: cytoplasmic microtubule, extracellular ...
Does Knockout of Zfp414 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Zfp414
protein/peptide distribution
myoblast cell line
Gene: Zfp414 (zinc finger protein 414) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, metal ion binding, molecular_function, zinc ion binding Pathways: UniProt: Q9DCK4 Entrez ID: 328801
Does Knockout of Slc25a1 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Slc25a1
protein/peptide distribution
myoblast cell line
Gene: Slc25a1 (solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial citrate transmembrane transport, negative regulation of ferroptosis, transmembrane transport; MF: antiporter activ...
Does Knockout of Pcdhgc3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Pcdhgc3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Pcdhgc3 (protocadherin gamma subfamily C, 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules, negative re...
Does Knockout of Mrpl23 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Mrpl23
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Mrpl23 (mitochondrial ribosomal protein L23) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: cytosolic ribosome, fibrillar center, mitochondrial inner membrane, mitochondrial large r...
Does Knockout of Psmc4 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Psmc4
cell proliferation
Mouse kidney carcinoma cell
Gene: Psmc4 (proteasome (prosome, macropain) 26S subunit, ATPase, 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blastocyst development, proteasome-mediated ubiquitin-dependent protein catabolic process; MF: ATP binding, ATP hydrolysis activity, nucleotide binding, pr...
Does Knockout of Mc5r in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Mc5r
protein/peptide accumulation
Regulatory T cell
Gene: Mc5r (melanocortin 5 receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, regulation of feeding behavior, signal transduction; MF: G protein...
Does Knockout of Eomes in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Eomes
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Eomes (eomesodermin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CD8-positive, alpha-beta T cell differentiation involved in immune response, adaptive immune response, anatomical structure morphogenesis, astrocyte differentiation, blastocyst development, brain d...
Does Knockout of Rab37 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Rab37
phagocytosis
macrophage
Gene: Rab37 (RAB37, member RAS oncogene family) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of autophagy, protein transport, regulation of exocytosis, regulation of eye photoreceptor cell development; MF: G protein activity, GTP binding, GTPase act...
Does Knockout of Prpf3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Prpf3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Prpf3 (pre-mRNA processing factor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome, spliceosomal tri-snRNP complex assembly; MF: identical protein binding; CC: Cajal body, U2-type precatalytic spliceoso...
Does Knockout of Vps37c in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Vps37c
cell proliferation
Mouse kidney carcinoma cell
Gene: Vps37c (vacuolar protein sorting 37C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: macroautophagy, multivesicular body assembly, protein targeting to membrane, protein targeting to vacuole, protein transport, ubiquitin-dependent protein catabolic process via the ...
Does Knockout of Ncdn in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Ncdn
response to virus
Microglial Cell Line
Gene: Ncdn (neurochondrin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bone resorption, neuron projection development, regulation of neuronal synaptic plasticity, regulation of postsynaptic neurotransmitter receptor internalization; CC: axon, cell projection, cytoplas...
Does Knockout of Phip in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Phip
cell proliferation
Colonic Cancer Cell Line
Gene: Phip (pleckstrin homology domain interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, cytoskeleton organization, insulin receptor signaling pathway, negative regulation of apoptotic process, negative regulation of extrinsic ap...
Does Knockout of Psmb1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Psmb1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Psmb1 (proteasome (prosome, macropain) subunit, beta type 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteolysis involved in protein catabolic process; CC: cytoplasm, cytosol, nucleoplasm, nucleus, proteasome complex, proteasome core complex, proteasome core...
Does Knockout of Il18r1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Il18r1
protein/peptide distribution
myoblast cell line
Gene: Il18r1 (interleukin 18 receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T-helper 1 cell differentiation, adaptive immune response, immune response, inflammatory response, interleukin-18-mediated signaling pathway, natural killer cell activation, negative ...
Does Knockout of Mrpl50 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Mrpl50
protein/peptide accumulation
Embryonic Cell Line
Gene: Mrpl50 (mitochondrial ribosomal protein L50) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytosol, mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, ribonucleoprotein complex, ribosome Pathways: Metabolism of proteins, M...
Does Knockout of Dct in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Dct
protein/peptide accumulation
Regulatory T cell
Gene: Dct (dopachrome tautomerase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell development, developmental pigmentation, melanin biosynthetic process, melanin biosynthetic process from tyrosine, pigmentation, positive regulation of neuroblast proliferation, respon...
Does Knockout of Srsf3 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Srsf3
cell proliferation
Colonic Cancer Cell Line
Gene: Srsf3 (serine and arginine-rich splicing factor 3) Type: protein-coding Summary: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM...
Does Knockout of Sla in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Sla
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Sla (src-like adaptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of MAPK cascade, signal transduction; MF: epidermal growth factor receptor binding, phosphotyrosine residue binding, protein binding; CC: COP9 signalosome, cytoplasm, endosome, nucleop...
Does Knockout of Fmo6 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Fmo6
cell proliferation
Melanoma Cell Line
Gene: Fmo6 (flavin containing monooxygenase 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: taurine biosynthetic process, xenobiotic metabolic process; MF: N,N-dimethylaniline monooxygenase activity, NADP binding, flavin adenine dinucleotide binding, monooxygenase acti...
Does Knockout of Tpt1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Tpt1
cell proliferation
Melanoma Cell Line
Gene: Tpt1 (tumor protein, translationally-controlled 1) Type: protein-coding Summary: Enables DNA-binding transcription factor binding activity. Involved in negative regulation of ectoderm development and stem cell population maintenance. Located in nucleoplasm. Is expressed in cerebral cortex ventricu...
Does Knockout of Vmn2r38 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Vmn2r38
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Vmn2r38 (vomeronasal 2, receptor 38) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: G3UYA...
Does Knockout of Snrnp40 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Snrnp40
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Snrnp40 (small nuclear ribonucleoprotein 40 (U5)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, RNA splicing, via transesterification reactions, mRNA processing; CC: U2-type catalytic step 2 spliceosome, U4/U6 x U5 tri-snRNP complex, U5 snRNP, cataly...
Does Knockout of Mgat1 in Melanoma Cell Line causally result in cell proliferation?
1
2,492
Knockout
Mgat1
cell proliferation
Melanoma Cell Line
Gene: Mgat1 (mannoside acetylglucosaminyltransferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: UDP-N-acetylglucosamine catabolic process, in utero embryonic development, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein glycos...
Does Knockout of Fndc8 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Fndc8
protein/peptide accumulation
Embryonic Cell Line
Gene: Fndc8 (fibronectin type III domain containing 8) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9D2H8 Entrez ID: 78919
Does Knockout of Wars2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,172
Knockout
Wars2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Wars2 (tryptophanyl tRNA synthetase 2 (mitochondrial)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial tryptophanyl-tRNA aminoacylation, positive regulation of angiogenesis, tRNA aminoacylation for protein translation, translation, tryptophanyl-tRNA am...
Does Knockout of Chchd10 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Chchd10
protein/peptide distribution
myoblast cell line
Gene: Chchd10 (coiled-coil-helix-coiled-coil-helix domain containing 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: inner mitochondrial membrane organization, mitochondrial membrane organization, mitochondrion organization; CC: MICOS complex, mitochondrial intermembr...
Does Knockout of Arhgap44 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Arhgap44
protein/peptide accumulation
Embryonic Cell Line
Gene: Arhgap44 (Rho GTPase activating protein 44) Type: protein-coding Summary: No summary available. Gene Ontology: BP: modification of postsynaptic structure, modulation of chemical synaptic transmission, negative regulation of Rac protein signal transduction, negative regulation of filopodiu...
Does Knockout of Uqcrq in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Uqcrq
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Uqcrq (ubiquinol-cytochrome c reductase, complex III subunit VII) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular respiration, cerebellar Purkinje cell layer development, hippocampus development, hypothalamus development, midbrain development, mitochondrial...
Does Knockout of Zfp654 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Zfp654
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Zfp654 (zinc finger protein 654) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, metal ion binding, zinc ion binding; CC: nucleus Pathways: UniProt: Q9DAU9 ...
Does Knockout of Urm1 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Urm1
cell proliferation
Melanoma Cell Line
Gene: Urm1 (ubiquitin related modifier 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein urmylation, tRNA processing, tRNA thio-modification, tRNA wobble uridine modification; MF: protein tag activity, sulfur carrier activity; CC: cytoplasm, cytosol, nucleus ...
Does Knockout of Neu4 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Neu4
cell proliferation
Embryonic Stem Cell Line
Gene: Neu4 (sialidase 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ganglioside catabolic process, glycoprotein catabolic process, lipid catabolic process, lipid metabolic process, negative regulation of neuron projection development, oligosaccharide catabolic proces...
Does Knockout of Cct7 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Cct7
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cct7 (chaperonin containing TCP1 subunit 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: binding of sperm to zona pellucida, positive regulation of telomere maintenance via telomerase, protein folding, protein stabilization; MF: ATP binding, ATP hydrolysis activi...
Does Knockout of Jdp2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Jdp2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Jdp2 (Jun dimerization protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin remodeling, negative regulation of fat cell differentiation, negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation ...
Does Knockout of Mrpl54 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Mrpl54
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Mrpl54 (mitochondrial ribosomal protein L54) Type: protein-coding Summary: Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including brain; brown fat; early conceptus; gonad; ...
Does Knockout of Gm19965 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Gm19965
cell proliferation
Mouse kidney carcinoma cell
Gene: Gm19965 (predicted gene, 19965) Type: pseudo Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regu...
Does Knockout of Gatb in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Gatb
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Gatb (glutamyl-tRNA amidotransferase subunit B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glutaminyl-tRNAGln biosynthesis via transamidation, mitochondrial translation, translation; MF: ATP binding, carbon-nitrogen ligase activity, with glutamine as amido-N-do...
Does Knockout of Aadat in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Aadat
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Aadat (aminoadipate aminotransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 2-oxoglutarate metabolic process, L-lysine catabolic process to acetyl-CoA via saccharopine, alpha-amino acid metabolic process, glutamate metabolic process, kynurenine metabolic p...
Does Knockout of Rnaseh2c in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Rnaseh2c
protein/peptide distribution
myoblast cell line
Gene: Rnaseh2c (ribonuclease H2, subunit C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA catabolic process, mismatch repair; CC: nucleus, ribonuclease H2 complex Pathways: DNA replication - Mus musculus (mouse) UniProt: Q9CQ18 Entrez ID: 6...
Does Knockout of Cyc1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Cyc1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cyc1 (cytochrome c-1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular respiration, mitochondrial electron transport, ubiquinol to cytochrome c, proton transmembrane transport, response to glucagon; MF: electron transfer activity, heme binding, metal ion bin...
Does Knockout of Tubg1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Tubg1
cell proliferation
Embryonic Stem Cell Line
Gene: Tubg1 (tubulin, gamma 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic microtubule organization, meiotic spindle organization, microtubule nucleation, microtubule-based process, mitotic cell cycle, mitotic sister chromatid segregation, mitotic spindle ...
Does Knockout of Swap70 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Swap70
protein/peptide distribution
Microglial Cell Line
Gene: Swap70 (SWA-70 protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament bundle assembly, isotype switching, negative regulation of actin filament depolymerization, negative regulation of cell-cell adhesion mediated by integrin, positive regulation of ...
Does Knockout of Rnf166 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Rnf166
cell proliferation
Colonic Cancer Cell Line
Gene: Rnf166 (ring finger protein 166) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagy, immune system process, innate immune response, protein polyubiquitination, protein ubiquitination, ubiquitin-dependent protein catabolic process; MF: metal ion binding, trans...
Does Knockout of Pcdh17 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Pcdh17
cell proliferation
Colonic Cancer Cell Line
Gene: Pcdh17 (protocadherin 17) Type: protein-coding Summary: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical...
Does Knockout of Gng7 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Gng7
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Gng7 (guanine nucleotide binding protein (G protein), gamma 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, behavioral fear response, locomotory behavior, receptor guanylyl cyclase signaling pathway, regulation of ade...
Does Knockout of AY761185 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
AY761185
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: AY761185 (cDNA sequence AY761185) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, defense response, defense response to Gram-negative bacterium, defense response...
Does Knockout of Ranbp2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Ranbp2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ranbp2 (RAN binding protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NLS-bearing protein import into nucleus, centrosome localization, cytoplasmic pattern recognition receptor signaling pathway, intracellular glucose homeostasis, mRNA transport, negative r...
Does Knockout of Nop56 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Nop56
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Nop56 (NOP56 ribonucleoprotein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ribosomal small subunit biogenesis, ribosome biogenesis; MF: RNA binding, histone methyltransferase binding, snoRNA binding; CC: box C/D methylation guide snoRNP complex, cytoplasm, fibr...
Does Knockout of Ccdc124 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Ccdc124
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ccdc124 (coiled-coil domain containing 124) Type: protein-coding Summary: Predicted to enable transcription coactivator activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in cytosol and plasma membrane. Predicted to be active in nucleus. Orthologous t...
Does Knockout of Lmo3 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Lmo3
response to virus
Embryonic Fibroblast Cell Line
Gene: Lmo3 (LIM domain only 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: exploration behavior, negative regulation of ERK1 and ERK2 cascade, positive regulation of fat cell differentiation, positive regulation of nuclear receptor-mediated glucocorticoid signaling pa...
Does Knockout of Ppa2 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Ppa2
cell proliferation
Melanoma Cell Line
Gene: Ppa2 (pyrophosphatase (inorganic) 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: diphosphate metabolic process, phosphate-containing compound metabolic process, regulation of mitochondrial membrane potential; MF: hydrolase activity, inorganic diphosphate phospha...
Does Knockout of Espn in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Espn
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Espn (espin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament bundle assembly, actin filament network formation, locomotory behavior, microvillar actin bundle assembly, negative regulation of cytoskeleton organization, parallel actin filament bundle as...
Does Knockout of Rhox1 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Rhox1
response to virus
Microglial Cell Line
Gene: Rhox1 (reproductive homeobox 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription activator acti...
Does Knockout of Parp1 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Parp1
cell proliferation
Melanoma Cell Line
Gene: Parp1 (poly (ADP-ribose) polymerase family, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ATP generation from poly-ADP-D-ribose, DNA ADP-ribosylation, DNA damage response, DNA metabolic process, DNA repair, DNA repair-dependent chromatin remodeling, apop...
Does Knockout of Dmxl2 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Dmxl2
cell proliferation
Mouse kidney carcinoma cell
Gene: Dmxl2 (Dmx-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, chemical synaptic transmission, corpus callosum development, glucose homeostasis, sensory perception of smell, spermatogenesis, vacuolar acidification; CC: RAVE complex, cytoplasmi...
Does Knockout of Dusp12 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Dusp12
cell proliferation
Embryonic Stem Cell Line
Gene: Dusp12 (dual specificity phosphatase 12) Type: protein-coding Summary: No summary available. Gene Ontology: MF: hydrolase activity, kinase binding, metal ion binding, phosphatase activity, phosphoprotein phosphatase activity, protein serine/threonine phosphatase activity, protein tyrosine...
Does Knockout of Iqgap1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Iqgap1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Iqgap1 (IQ motif containing GTPase activating protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, caveola assembly, cell migration, cellular response to calcium ion, cellular response to epidermal growth factor stimulus, cellular response to fib...
Does Knockout of Ctnnd2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ctnnd2
cell proliferation
Embryonic Stem Cell Line
Gene: Ctnnd2 (catenin delta 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell-cell adhesion, dendritic spine morphogenesis, learning, morphogenesis of a branching structure, neuron projection retraction, positive regulation of axon extension, regulati...
Does Knockout of Dennd2d in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Dennd2d
protein/peptide distribution
myoblast cell line
Gene: Dennd2d (DENN domain containing 2D) Type: protein-coding Summary: No summary available. Gene Ontology: MF: guanyl-nucleotide exchange factor activity; CC: cytoplasm, cytosol, nucleoplasm Pathways: Membrane Trafficking, RAB GEFs exchange GTP for GDP on RABs, Rab regulation of traf...
Does Knockout of Kcnab3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Kcnab3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Kcnab3 (potassium voltage-gated channel, shaker-related subfamily, beta member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion transmembrane transport, potassium ion transport, regula...
Does Knockout of Lrrc25 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Lrrc25
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Lrrc25 (leucine rich repeat containing 25) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, canonical NF-kappaB signal transduction, connective tissue replacement involved in inflammatory response wound healing, gene expression, heart development,...
Does Knockout of Ddx39b in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Ddx39b
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ddx39b (DEAD box helicase 39b) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA export from nucleus, mRNA processing, mRNA splicing, via spliceosome, mRNA transport, positive regulation of DNA biosynthetic process, positive regulation of cell growt...
Does Knockout of Bpifb4 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Bpifb4
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Bpifb4 (BPI fold containing family B, member 4) Type: protein-coding Summary: No summary available. Gene Ontology: MF: lipid binding, molecular_function; CC: actin cytoskeleton, cytoplasm, cytosol, extracellular region Pathways: Antimicrobial peptides, Immune System, Innate Immun...
Does Knockout of Eif4a1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Eif4a1
cell proliferation
Mouse kidney carcinoma cell
Gene: Eif4a1 (eukaryotic translation initiation factor 4A1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translational initiation, positive regulation of transcription by RNA polymerase II, translation, translational initiation; MF: ATP binding, ATP hydroly...
Does Knockout of Rspo1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Rspo1
cell proliferation
Embryonic Stem Cell Line
Gene: Rspo1 (R-spondin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, male meiotic nuclear division, negative regulation of eating behavior, positive regulation of Wnt signaling pathway, positive regulation of canonical Wnt signaling pathway, po...
Does Knockout of Bccip in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Bccip
protein/peptide distribution
myoblast cell line
Gene: Bccip (BRCA2 and CDKN1A interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, establishment of mitotic spindle orientation, microtubule anchoring, microtubule cytoskeleton organization, mitotic spindle assembly, mitoti...
Does Knockout of Orm1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Orm1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Orm1 (orosomucoid 1) Type: protein-coding Summary: This gene encodes a member of the lipocalin family of proteins. The encoded protein is an abundant acute-phase protein that is synthesized by hepatocytes in response to cytokines during the acute phase response. The encoded protein may regulate in...
Does Knockout of Eif2b5 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Eif2b5
response to virus
Microglial Cell Line
Gene: Eif2b5 (eukaryotic translation initiation factor 2B, subunit 5 epsilon) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell receptor signaling pathway, astrocyte development, astrocyte differentiation, cytoplasmic translational initiation, hippocampus development...
Does Knockout of Epb41l1 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Epb41l1
protein/peptide distribution
Microglial Cell Line
Gene: Epb41l1 (erythrocyte membrane protein band 4.1 like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actomyosin structure organization, cortical actin cytoskeleton organization, regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane...
Does Knockout of Myh7b in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Myh7b
protein/peptide distribution
myoblast cell line
Gene: Myh7b (myosin, heavy chain 7B, cardiac muscle, beta) Type: protein-coding Summary: This gene encodes a myosin heavy chain. The encoded protein forms a hexamer comprised of two heavy chains, two alkali light chains, and two regulatory light chain components. This complex functions in muscle contrac...
Does Knockout of Emg1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Emg1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Emg1 (EMG1 N1-specific pseudouridine methyltransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blastocyst development, methylation, nucleologenesis, rRNA base methylation, rRNA processing, ribosomal small subunit biogenesis, ribosome biogenesis; MF: RNA bin...
Does Knockout of Chrac1 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Chrac1
protein/peptide distribution
myoblast cell line
Gene: Chrac1 (chromatin accessibility complex 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA biosynthetic process, DNA-templated DNA replication, chromatin remodeling, nucleosome assembly, regulation of DNA replication; MF: DNA binding, DNA-directed DNA polymerase...
Does Knockout of Ube2i in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Ube2i
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ube2i (ubiquitin-conjugating enzyme E2I) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, chromosome segregation, modulation of chemical synaptic transmission, negative regulation of DNA-templated transcription, negative regulation of transcription by ...
Does Knockout of Kpna1 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Kpna1
protein/peptide distribution
Microglial Cell Line
Gene: Kpna1 (karyopherin subunit alpha 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NLS-bearing protein import into nucleus, postsynapse to nucleus signaling pathway, protein import into nucleus, protein transport, regulation of apoptotic process, regulation of cano...
Does Knockout of Cnnm3 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Cnnm3
cell cycle progression
breast epithelium
Gene: Cnnm3 (cyclin M3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: magnesium ion homeostasis, monoatomic ion transport, transmembrane transport; CC: membrane, plasma membrane Pathways: UniProt: Q32NY4 Entrez ID: 94218
Does Knockout of Rimkla in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Rimkla
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rimkla (ribosomal modification protein rimK-like family member A) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, N-acetyl-L-aspartate-L-glutamate ligase activity, ligase activity, metal ion binding, nucleotide binding; CC: cytoplasm Pathways: ...
Does Knockout of Casp14 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Casp14
protein/peptide distribution
Microglial Cell Line
Gene: Casp14 (caspase 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, positive regulation of neuron apoptotic process, proteolysis; MF: cysteine-type endopeptidase activity, cysteine-type peptidase activity, hydrolase activity, peptidase activity...
Does Knockout of Myo5c in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Myo5c
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Myo5c (myosin VC) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament organization, endocytosis, establishment of secretory granule localization, phenol-containing compound metabolic process, pigmentation, protein transport, secretory granule localization...
Does Knockout of Ttll11 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Ttll11
autophagy
Embryonic Fibroblast Cell Line
Gene: Ttll11 (tubulin tyrosine ligase-like family, member 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule cytoskeleton organization, microtubule severing; MF: ATP binding, ligase activity, metal ion binding, nucleotide binding, protein-glutamic acid ligase...
Does Knockout of Serpina3j in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Serpina3j
cell proliferation
Embryonic Stem Cell Line
Gene: Serpina3j (serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3J) Type: protein-coding Summary: No summary available. Gene Ontology: MF: serine-type endopeptidase inhibitor activity; CC: extracellular space Pathways: UniProt:...
Does Knockout of Rab3il1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Rab3il1
protein/peptide distribution
myoblast cell line
Gene: Rab3il1 (RAB3A interacting protein (rabin3)-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: guanyl-nucleotide exchange factor activity, identical protein binding, kinase binding Pathways: Membrane Trafficking, RAB GEFs exchange GTP for GDP on RABs, ...
Does Knockout of Wdr45 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Wdr45
cell proliferation
Melanoma Cell Line
Gene: Wdr45 (WD repeat domain 45) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, autophagy, autophagy of mitochondrion, cellular response to starvation, glycophagy, nucleophagy, pexophagy, positive regulation of autophagosome assembly, protein loc...
Does Knockout of A4galt in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
A4galt
autophagy
Embryonic Fibroblast Cell Line
Gene: A4galt (alpha 1,4-galactosyltransferase) Type: protein-coding Summary: The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a ...
Does Knockout of Wfdc12 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Wfdc12
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Wfdc12 (WAP four-disulfide core domain 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, defense response to bacterium, innate immune response; MF: peptidase inhibitor activity, serine-type endopeptidase inhibitor activity; CC: extr...
Does Knockout of Hdac3 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,171
Knockout
Hdac3
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Hdac3 (histone deacetylase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair-dependent chromatin remodeling, cellular response to fluid shear stress, cellular response to mechanical stimulus, cellular response to parathyroid hormone stimulus, chromatin o...
Does Knockout of Zbtb46 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Zbtb46
protein/peptide distribution
myoblast cell line
Gene: Zbtb46 (zinc finger and BTB domain containing 46) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of dendritic cell differentiation, negative regulation of granulocyte differentiation, negative regulation of leukocyte activation, negative regulat...
Does Knockout of Mesp1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Mesp1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Mesp1 (mesoderm posterior 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, cardiac atrium formation, cardiac cell fate determination, cardiac muscle cell differentiation, cardiac vascular smooth muscle cell differentiation, cardiac ventric...
Does Knockout of Ino80 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Ino80
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ino80 (INO80 complex subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA metabolic process, DNA recombination, DNA repair, DNA-templated transcription, UV-damage excision repair, cell division, cellular response to UV, cellular response...
Does Knockout of Dennd2c in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Dennd2c
protein/peptide distribution
myoblast cell line
Gene: Dennd2c (DENN domain containing 2C) Type: protein-coding Summary: No summary available. Gene Ontology: MF: guanyl-nucleotide exchange factor activity Pathways: UniProt: G3UYA7, E9Q4E4 Entrez ID: 329727
Does Knockout of Tro in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Tro
protein/peptide accumulation
Regulatory T cell
Gene: Tro (trophinin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of cell growth, negative regulation of transcription by RNA polymerase II; CC: cytoplasm, nucleus, plasma membrane Pathways: UniProt: E9Q886, Q6DIC6, E9Q160, E9Q09...
Does Knockout of Dram1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Dram1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dram1 (DNA-damage regulated autophagy modulator 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, autophagy, cellular response to oxygen-glucose deprivation, regulation of autophagy; CC: cytoplasm, lysosomal membrane, lysosome, membrane ...
Does Knockout of D030028A08Rik in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
D030028A08Rik
protein/peptide distribution
Microglial Cell Line
Gene: D030028A08Rik (RIKEN cDNA D030028A08 gene) Type: ncRNA Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 319371
Does Knockout of Tbc1d10a in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Tbc1d10a
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tbc1d10a (TBC1 domain family, member 10a) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of proteolysis, retrograde transport, endosome to Golgi; MF: GTPase activator activity, PDZ domain binding, guanyl-nucleotide exchange factor activity; CC: ...
Does Knockout of Vmn2r103 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Vmn2r103
cell proliferation
Embryonic Stem Cell Line
Gene: Vmn2r103 (vomeronasal 2, receptor 103) Type: protein-coding Summary: Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: BP: G protein-coupled receptor signaling pathway, si...