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Does Knockout of Chrnb2 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Chrnb2
protein/peptide accumulation
Mouse cell
Gene: Chrnb2 (cholinergic receptor nicotinic beta 2 subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation, acetylcholine receptor signaling pathway, associative learning, behavioral response to nicotine, calcium ion transport, central nervous system n...
Does Knockout of Pdcd5 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Pdcd5
protein/peptide accumulation
Embryonic Cell Line
Gene: Pdcd5 (programmed cell death 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cellular response to transforming growth factor beta stimulus, negative regulation of protein folding, positive regulation of apoptotic process, positive regulation of...
Does Knockout of Rfx5 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Rfx5
cell proliferation
Colonic Cancer Cell Line
Gene: Rfx5 (regulatory factor X, 5 (influences HLA class II expression)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, positive regulation of MHC class II biosynthetic process, positive regulation of transcripti...
Does Knockout of Xrcc6 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Xrcc6
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Xrcc6 (X-ray repair complementing defective repair in Chinese hamster cells 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, V(D)J recombination, activation of innate immune response, cellular hyperosmotic salini...
Does Knockout of Dst in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Dst
protein/peptide distribution
myoblast cell line
Gene: Dst (dystonin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axonogenesis, cell adhesion, cell motility, cytoplasmic microtubule organization, cytoskeleton organization, hemidesmosome assembly, intermediate filament cytoskeleton organization, intracellular transpo...
Does Knockout of Tex38 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Tex38
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Tex38 (testis expressed 38) Type: protein-coding Summary: Predicted to be located in membrane. Is expressed in lung. Orthologous to human TEX38 (testis expressed 38). [provided by Alliance of Genome Resources, Apr 2025] Gene Ontology: MF: molecular_function, protein binding; CC: cellular_...
Does Knockout of Naca in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Naca
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Naca (nascent polypeptide-associated complex alpha polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: myoblast migration, negative regulation of protein localization to endoplasmic reticulum, positive regulation of DNA-templated transcription, protein targ...
Does Knockout of Slc17a2 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Slc17a2
response to virus
Embryonic Fibroblast Cell Line
Gene: Slc17a2 (solute carrier family 17 (sodium phosphate), member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transport, sodium ion transport, transmembrane transport, urate transport; MF: symporter activity, transmembrane transporter activity, urat...
Does Knockout of Gtf2b in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Gtf2b
cell proliferation
Embryonic Stem Cell Line
Gene: Gtf2b (general transcription factor IIB) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription initiation, RNA polymerase II core complex assembly, RNA polymerase II preinitiation complex assembly, chromatin remodeling, chromosome organization,...
Does Knockout of Appl1 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Appl1
protein/peptide distribution
myoblast cell line
Gene: Appl1 (adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adiponectin-activated signaling pathway, cellular response to hepatocyte growth factor stimulus, insulin receptor signalin...
Does Knockout of Pcgf6 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Pcgf6
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Pcgf6 (polycomb group ring finger 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin remodeling, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II...
Does Knockout of Mrpl45 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Mrpl45
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mrpl45 (mitochondrial ribosomal protein L45) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, ribonucleoprotein ...
Does Knockout of Dad1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Dad1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Dad1 (defender against cell death 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, blastocyst development, negative regulation of apoptotic process, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein glycosyla...
Does Knockout of Pds5a in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Pds5a
protein/peptide distribution
myoblast cell line
Gene: Pds5a (PDS5 cohesin associated factor A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterior/posterior pattern specification, cell division, embryonic skeletal system morphogenesis, enteric nervous system development, heart morphogenesis, lens development in ca...
Does Knockout of Mapk11 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Mapk11
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Mapk11 (mitogen-activated protein kinase 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, NLRP1 inflammasome complex assembly, bone development, cellular response to UV-B, cellular response to interleukin-1, cellular response to virus, intracellular...
Does Knockout of Krt1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Krt1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Krt1 (keratin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: complement activation, lectin pathway, establishment of skin barrier, intermediate filament organization, keratinization, negative regulation of inflammatory response, protein heterotetramerization; MF...
Does Knockout of Zfp318 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Zfp318
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Zfp318 (zinc finger protein 318) Type: protein-coding Summary: No summary available. Gene Ontology: BP: meiotic cell cycle, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription; MF: metal ion binding, nucleic acid binding, protein binding,...
Does Knockout of Kctd9 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Kctd9
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Kctd9 (potassium channel tetramerisation domain containing 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NK T cell lineage commitment, biological_process, cell maturation, gene expression, intracellular signal transduction, natural killer cell degranulation, na...
Does Knockout of Ppp4r2 in Lymphoma Cell Line causally result in response to chemicals?
1
1,551
Knockout
Ppp4r2
response to chemicals
Lymphoma Cell Line
Gene: Ppp4r2 (protein phosphatase 4, regulatory subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, hematopoietic progenitor cell differentiation, mRNA processing, regulation of double-strand break repair, regulation of double-strand break repair via ...
Does Knockout of Cdc45 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Cdc45
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Cdc45 (cell division cycle 45) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, DNA replication initiation, double-strand break repair via break-induced replication, mitotic DNA replication preinitiation complex assembly; MF: DNA replication origin b...
Does Knockout of Pea15a in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Pea15a
protein/peptide distribution
myoblast cell line
Gene: Pea15a (proliferation and apoptosis adaptor protein 15A) Type: protein-coding Summary: This gene encodes an adaptor protein that functions as a negative regulator of apoptosis induced by tumor necrosis factor-alpha, tumor necrosis factor-related apoptosis-inducing ligand, and Fas, through its inte...
Does Knockout of Prcd in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Prcd
response to virus
Microglial Cell Line
Gene: Prcd (photoreceptor disc component) Type: protein-coding Summary: No summary available. Gene Ontology: MF: opsin binding; CC: Golgi apparatus, cell projection, cytoplasm, endoplasmic reticulum, extracellular region, membrane, photoreceptor outer segment, photoreceptor outer segment membra...
Does Knockout of Sgta in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Sgta
cell proliferation
Colonic Cancer Cell Line
Gene: Sgta (small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, negative regulation of ERAD pathway, negative regulation of ubiquitin-dependent protein catabolic process, positive regulation ...
Does Knockout of D630023F18Rik in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
D630023F18Rik
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: D630023F18Rik (RIKEN cDNA D630023F18 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8C3M9 Entrez ID: 98303
Does Knockout of Mtf1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Mtf1
cell proliferation
Colonic Cancer Cell Line
Gene: Mtf1 (metal response element binding transcription factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, cartilage homeostasis, cellular response to zinc ion, central nervous system development, positive regulation of DNA-templated t...
Does Knockout of Nfxl1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Nfxl1
protein/peptide accumulation
Embryonic Cell Line
Gene: Nfxl1 (nuclear transcription factor, X-box binding-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA-binding transcription factor activity, DNA-binding transcr...
Does Knockout of H13 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
H13
protein/peptide accumulation
Embryonic Cell Line
Gene: H13 (histocompatibility 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: in utero embryonic development, membrane protein proteolysis, membrane protein proteolysis involved in retrograde protein transport, ER to cytosol, proteolysis, signal peptide processing; MF...
Does Knockout of Clpsl2 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Clpsl2
response to chemicals
Pancreatic Cancer Cell Line
Gene: Clpsl2 (colipase-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: digestion, lipid catabolic process, response to food; CC: cellular_component, extracellular region Pathways: UniProt: Q3UW21 Entrez ID: 328788
Does Knockout of Taar3 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Taar3
protein/peptide distribution
myoblast cell line
Gene: Taar3 (trace amine-associated receptor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled amine receptor activity, G protein-coupled rec...
Does Knockout of Zfp382 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Zfp382
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Zfp382 (zinc finger protein 382) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by ...
Does Knockout of Klhl28 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Klhl28
cell proliferation
Colonic Cancer Cell Line
Gene: Klhl28 (kelch-like 28) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, proteasome-mediated ubiquitin-dependent protein catabolic process; MF: molecular_function, ubiquitin-like ligase-substrate adaptor activity; CC: Cul3-RING ubiquitin ligase com...
Does Knockout of Atp6v1b2 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Atp6v1b2
cell proliferation
Mouse kidney carcinoma cell
Gene: Atp6v1b2 (ATPase, H+ transporting, lysosomal V1 subunit B2) Type: protein-coding Summary: Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in synaptic vesicle lumen acidification. Located in several cellular components, including apical plasma membrane; micro...
Does Knockout of Fscb in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Fscb
protein/peptide distribution
myoblast cell line
Gene: Fscb (fibrous sheath CABYR binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of protein sumoylation; MF: calcium ion binding, protein binding; CC: cell projection, cilium, motile cilium, sperm fibrous sheath, sperm principal piece ...
Does Knockout of Pex12 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Pex12
cell proliferation
Embryonic Stem Cell Line
Gene: Pex12 (peroxisomal biogenesis factor 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to reactive oxygen species, peroxisome organization, pexophagy, protein import into peroxisome matrix, protein import into peroxisome matrix, receptor recyclin...
Does Knockout of Ino80 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ino80
cell proliferation
Embryonic Stem Cell Line
Gene: Ino80 (INO80 complex subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA metabolic process, DNA recombination, DNA repair, DNA-templated transcription, UV-damage excision repair, cell division, cellular response to UV, cellular response...
Does Knockout of Cic in Malignant Peripheral Nerve Sheath Tumor (MPNST) cancer cell causally result in tumorigenicity?
1
2,184
Knockout
Cic
tumorigenicity
Malignant Peripheral Nerve Sheath Tumor (MPNST) cancer cell
Gene: Cic (capicua transcriptional repressor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, learning, lung alveolus development, memory, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, reg...
Does Knockout of Ddx24 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Ddx24
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ddx24 (DEAD box helicase 24) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase activity, hydrolase activity, nucleic acid binding, nucleotide binding; CC: cytoplasm, nucleolus, nucleus ...
Does Knockout of Rora in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Rora
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Rora (RAR-related orphan receptor alpha) Type: protein-coding Summary: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of thos...
Does Knockout of Nagpa in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Nagpa
cell cycle progression
breast epithelium
Gene: Nagpa (N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase) Type: protein-coding Summary: Predicted to enable N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity. Acts upstream of or within secretion of lysosomal enzymes. Predicted to be located in Golgi cist...
Does Knockout of Cpa5 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Cpa5
cell viability
Immortal mouse chromaffin cells
Gene: Cpa5 (carboxypeptidase A5) Type: protein-coding Summary: This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. The encoded preproprotein undergoes proteolytic processing that removes the N-terminal activation peptide to generate a functional enzyme. This gene is exp...
Does Knockout of Mtcl1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Mtcl1
cell proliferation
Mouse kidney carcinoma cell
Gene: Mtcl1 (microtubule crosslinking factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, chromosome segregation, establishment or maintenance of epithelial cell apical/basal polarity, microtubule bundle formation, positive regulation of protein targe...
Does Knockout of Cyp2j13 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Cyp2j13
protein/peptide distribution
myoblast cell line
Gene: Cyp2j13 (cytochrome P450, family 2, subfamily j, polypeptide 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: epoxygenase P450 pathway, icosanoid metabolic process, linoleic acid metabolic process, organic acid metabolic process, xenobiotic metabolic process; MF:...
Does Knockout of Dclk2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Dclk2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Dclk2 (doublecortin-like kinase 2) Type: protein-coding Summary: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization,...
Does Knockout of Foxred1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Foxred1
protein/peptide distribution
myoblast cell line
Gene: Foxred1 (FAD-dependent oxidoreductase domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial respiratory chain complex I assembly; CC: cytoplasm, membrane, mitochondrial inner membrane, mitochondrion Pathways: UniProt: ...
Does Knockout of Pnn in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Pnn
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Pnn (pinin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, cell-cell adhesion, mRNA processing; CC: anchoring junction, catalytic step 2 spliceosome, cytoplasm, desmosome, exon-exon junction complex, nuclear speck, nucleus, spliceosomal complex ...
Does Knockout of Dscc1 in Melanoma Cell Line causally result in cell proliferation?
1
1,158
Knockout
Dscc1
cell proliferation
Melanoma Cell Line
Gene: Dscc1 (DNA replication and sister chromatid cohesion 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, maintenance of mitotic sister chromatid cohesion, mitotic sister chromatid cohesion, positive regulation of DNA-directed DNA polymerase activity,...
Does Knockout of Ciz1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Ciz1
protein/peptide distribution
myoblast cell line
Gene: Ciz1 (CDKN1A interacting zinc finger protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maintenance of protein location in nucleus, positive regulation of DNA-templated DNA replication initiation, random inactivation of X chromosome; MF: cyclin binding, meta...
Does Knockout of Ndufaf1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Ndufaf1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Ndufaf1 (NADH:ubiquinone oxidoreductase complex assembly factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chaperone-mediated protein complex assembly, mitochondrial electron transport, NADH to ubiquinone, mitochondrial respiratory chain complex I assembly; ...
Does Knockout of 9030624G23Rik in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
9030624G23Rik
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: 9030624G23Rik (RIKEN cDNA 9030624G23 gene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, regulation of DNA-templated transcription; CC: cellular_component, nucleus Pathways: UniProt: Q9D308 Entrez ID: 66808
Does Knockout of Ppil2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Ppil2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Ppil2 (peptidylprolyl isomerase (cyclophilin)-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, protein folding, protein localization to plasma membrane, protein polyubiquitination, protein ubiquitination; MF: peptidyl-prolyl cis...
Does Knockout of Psenen in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Psenen
cell viability
Immortal mouse chromaffin cells
Gene: Psenen (presenilin enhancer gamma secretase subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch receptor processing, Notch signaling pathway, amyloid precursor protein catabolic process, amyloid precursor protein metabolic process, amyloid-beta formation,...
Does Knockout of Numa1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Numa1
cell proliferation
Colonic Cancer Cell Line
Gene: Numa1 (nuclear mitotic apparatus protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anastral spindle assembly, astral microtubule organization, cell division, chromosome segregation, establishment of mitotic spindle orientation, meiotic cell cycle, microtubu...
Does Knockout of Fads3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Fads3
cell proliferation
Mouse kidney carcinoma cell
Gene: Fads3 (fatty acid desaturase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid biosynthetic process, fatty acid metabolic process, gene expression, lipid metabolic process, sphingolipid metabolic process, unsaturated fatty acid biosynthetic process; MF: ...
Does Knockout of Sgtb in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Sgtb
cell proliferation
Melanoma Cell Line
Gene: Sgtb (small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: post-translational protein targeting to endoplasmic reticulum membrane, protein heterooligomerization, protein homooligomerization; MF: Hsp70 ...
Does Knockout of Mrps21 in Melanoma Cell Line causally result in cell proliferation?
1
1,158
Knockout
Mrps21
cell proliferation
Melanoma Cell Line
Gene: Mrps21 (mitochondrial ribosomal protein S21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondrion, ribon...
Does Knockout of Ankrd40 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ankrd40
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ankrd40 (ankyrin repeat domain 40) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q5SUE8 Entrez ID: 71452
Does Knockout of Sbf1 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Sbf1
tumorigenicity
Colonic Cancer Cell Line
Gene: Sbf1 (SET binding factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of cell growth, spermatid development, spermatogenesis; MF: guanyl-nucleotide exchange factor activity, phosphatase regulator activity, pseudophosphatase activity; CC: cell projec...
Does Knockout of Dlgap5 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Dlgap5
cell proliferation
Embryonic Stem Cell Line
Gene: Dlgap5 (DLG associated protein 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: centrosome localization, chromosome segregation, kinetochore assembly, mitotic spindle organization, regulation of mitotic cell cycle, signaling; CC: cytoplasm, cytoskeleton, cytosol, ...
Does Knockout of Sdhaf1 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Sdhaf1
cell proliferation
Melanoma Cell Line
Gene: Sdhaf1 (succinate dehydrogenase complex assembly factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial respiratory chain complex II assembly; CC: mitochondrial matrix, mitochondrion, nucleoplasm Pathways: Aerobic respiration and respirator...
Does Knockout of Uri1 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Uri1
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Uri1 (URI1, prefoldin-like chaperone) Type: protein-coding Summary: Predicted to enable several functions, including RNA polymerase II complex binding activity; phosphatase inhibitor activity; and transcription corepressor activity. Predicted to be involved in several processes, including intrinsi...
Does Knockout of Dhx29 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Dhx29
autophagy
Embryonic Fibroblast Cell Line
Gene: Dhx29 (DExH-box helicase 29) Type: protein-coding Summary: No summary available. Gene Ontology: BP: formation of translation preinitiation complex, positive regulation of translational initiation, ribosome assembly, translation, translational initiation; MF: ATP binding, ATP hydrolysis ac...
Does Knockout of Ccl21b in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Ccl21b
protein/peptide distribution
myoblast cell line
Gene: Ccl21b (C-C motif chemokine ligand 21B (leucine)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CCL21-activated CCR7 signaling pathway, G protein-coupled receptor signaling pathway, antimicrobial humoral immune response mediated by antimicrobial peptide, cell chem...
Does Knockout of Acsl6 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Acsl6
cell proliferation
Colonic Cancer Cell Line
Gene: Acsl6 (acyl-CoA synthetase long-chain family member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid metabolic process, fatty acid transport, lipid metabolic process, long-chain fatty acid metabolic process, long-chain fatty-acyl-CoA biosynthetic proces...
Does Knockout of Prpf18 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Prpf18
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Prpf18 (pre-mRNA processing factor 18) Type: protein-coding Summary: Predicted to be involved in generation of catalytic spliceosome for second transesterification step and negative regulation of protein metabolic process. Predicted to be located in nuclear speck. Predicted to be part of U2-type p...
Does Knockout of Emilin1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Emilin1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Emilin1 (elastin microfibril interfacer 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aortic valve morphogenesis, cell adhesion, cell adhesion mediated by integrin, cell migration, cell-matrix adhesion, elastic fiber assembly, extracellular matrix organization,...
Does Knockout of Rbpms in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Rbpms
cell viability
Immortal mouse chromaffin cells
Gene: Rbpms (RNA binding protein gene with multiple splicing) Type: protein-coding Summary: No summary available. Gene Ontology: BP: SMAD protein signal transduction, positive regulation of DNA-templated transcription, protein-containing complex assembly, regulation of alternative mRNA splicing...
Does Knockout of Tomm6 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Tomm6
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tomm6 (translocase of outer mitochondrial membrane 6) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane, mitochondrial outer membrane, mitochondrial outer membrane translocase complex, mitochondrion Pathways: Autophagy, Macroautophagy, Mitophagy, PIN...
Does Knockout of Dhx33 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Dhx33
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Dhx33 (DEAH-box helicase 33) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of MAPK cascade, positive regulation of NF-kappaB transcription factor activity, positive regulation of NLRP3 inflammasome complex assembly, positive regulation of trans...
Does Knockout of Sdk2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Sdk2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Sdk2 (sidekick cell adhesion molecule 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: camera-type eye photoreceptor cell differentiation, cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules, retina layer formation, synapse assembly; CC:...
Does Knockout of Nhej1 in Lymphoma Cell Line causally result in response to chemicals?
1
1,558
Knockout
Nhej1
response to chemicals
Lymphoma Cell Line
Gene: Nhej1 (non-homologous end joining factor 1) Type: protein-coding Summary: Predicted to enable DNA end binding activity and DNA polymerase binding activity. Involved in double-strand break repair via nonhomologous end joining. Predicted to be located in fibrillar center and nucleoplasm. Predicted t...
Does Knockout of Sbds in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Sbds
cell proliferation
Embryonic Stem Cell Line
Gene: Sbds (SBDS ribosome maturation factor) Type: protein-coding Summary: This gene encodes a protein that is necessary for ribosome function and maintaining normal levels of protein synthesis. The encoded protein may function to activate ribosomes for translation, and may be involved in cellular respo...
Does Knockout of Pepd in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Pepd
protein/peptide distribution
myoblast cell line
Gene: Pepd (peptidase D) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CARD8 inflammasome complex assembly, collagen catabolic process, negative regulation of programmed cell death, proteolysis; MF: dipeptidase activity, hydrolase activity, manganese ion binding, metal ...
Does Knockout of Trim71 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Trim71
cell proliferation
Melanoma Cell Line
Gene: Trim71 (tripartite motif-containing 71) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 3'-UTR-mediated mRNA destabilization, G1/S transition of mitotic cell cycle, fibroblast growth factor receptor signaling pathway, miRNA processing, miRNA-mediated gene silencing ...
Does Knockout of Ppp2r3a in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Ppp2r3a
protein/peptide accumulation
Embryonic Cell Line
Gene: Ppp2r3a (protein phosphatase 2, regulatory subunit B'', alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: eye photoreceptor cell differentiation, negative regulation of canonical Wnt signaling pathway, positive regulation of canonical Wnt signaling pathway, pos...
Does Knockout of Zp2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Zp2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Zp2 (zona pellucida glycoprotein 2) Type: protein-coding Summary: This gene encodes a member of the zona pellucida family of glycoproteins that play an important role in the survival of growing oocytes, successful fertilization and the passage of early embryos through the oviduct. The encoded prep...
Does Knockout of Fancb in Lymphoma Cell Line causally result in response to chemicals?
1
1,545
Knockout
Fancb
response to chemicals
Lymphoma Cell Line
Gene: Fancb (Fanconi anemia, complementation group B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, bone marrow development, cellular response to camptothecin, cellular response to xenobiotic stimulus, gene expression, hematopoietic stem...
Does Knockout of Dusp16 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Dusp16
cell proliferation
Embryonic Stem Cell Line
Gene: Dusp16 (dual specificity phosphatase 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of MAPK cascade, signal transduction; MF: JUN kinase binding, MAP kinase tyrosine phosphatase activity, MAP kinase tyrosine/serine/threonine phosphatase acti...
Does Knockout of Mbp in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Mbp
cell proliferation
Mouse kidney carcinoma cell
Gene: Mbp (myelin basic protein) Type: protein-coding Summary: The protein encoded by the classic Mbp gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, Mbp-related transcripts are also present in the bone marrow and the immune system. ...
Does Knockout of Gtf2f2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Gtf2f2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gtf2f2 (general transcription factor IIF, polypeptide 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, positive regulation of transcription by RNA polymerase II, transcription by RNA polymerase II, transcription el...
Does Knockout of Sp110 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Sp110
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sp110 (Sp110 nuclear body protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, immune system process, innate immune response, positive regulation of apoptotic process, regulation of transcription by RNA polymerase II, response to bacterium; MF...
Does Knockout of Ccnt1 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Ccnt1
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Ccnt1 (cyclin T1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, host-mediated activation of viral transcription, positive regulation of DNA-templated transcription, elongation, positive regulation of transcription by RNA polymerase II, positive regu...
Does Knockout of Naa25 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Naa25
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Naa25 (N(alpha)-acetyltransferase 25, NatB auxiliary subunit) Type: protein-coding Summary: No summary available. Gene Ontology: CC: Golgi apparatus, NatB complex, cytoplasm, cytosol Pathways: UniProt: Q8BWZ3 Entrez ID: 231713
Does Knockout of Mre11a in Lymphoma Cell Line causally result in response to chemicals?
1
1,525
Knockout
Mre11a
response to chemicals
Lymphoma Cell Line
Gene: Mre11a (MRE11A homolog A, double strand break repair nuclease) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA double-strand break processing, DNA repair, DNA strand resection involved in replication fork processing, R-loop processing, cell ...
Does Knockout of Gm1647 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Gm1647
protein/peptide distribution
Microglial Cell Line
Gene: Gm1647 (predicted gene 1647) Type: ncRNA Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 381452
Does Knockout of Mtrf1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Mtrf1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mtrf1 (mitochondrial translational release factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translational termination, translation, translational termination; MF: translation release factor activity, translation release factor activity, codon ...
Does Knockout of Ndfip1 in Lymphoma Cell Line causally result in response to chemicals?
0
1,543
Knockout
Ndfip1
response to chemicals
Lymphoma Cell Line
Gene: Ndfip1 (Nedd4 family interacting protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular iron ion homeostasis, metal ion transport, negative regulation of CD4-positive, alpha-beta T cell proliferation, negative regulation of gene expression, negativ...
Does Knockout of Spns3 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Spns3
protein/peptide distribution
myoblast cell line
Gene: Spns3 (SPNS lysolipid transporter 3, sphingosine-1-phosphate (putative)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid transport, transmembrane transport; MF: transmembrane transporter activity; CC: membrane Pathways: UniProt: Q9D232 ...
Does Knockout of Mrpl11 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Mrpl11
cell proliferation
Colonic Cancer Cell Line
Gene: Mrpl11 (mitochondrial ribosomal protein L11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: large ribosomal subunit rRNA binding, structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large r...
Does Knockout of Nsmce3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Nsmce3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nsmce3 (NSE3 homolog, SMC5-SMC6 complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, cellular response to UV, cellular response to hydroxyurea, cellular response to radiation, negative regulation of t...
Does Knockout of Atg3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Atg3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Atg3 (autophagy related 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, autophagy, autophagy of mitochondrion, glycophagy, macroautophagy, mitochondrial fragmentation involved in apoptotic process, negative regulation of phagocytosis, nucl...
Does Knockout of Pitpnm1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Pitpnm1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Pitpnm1 (phosphatidylinositol transfer protein, membrane-associated 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intermembrane lipid transfer, phospholipid transport, protein transport; MF: calcium ion binding, metal ion binding, phosphatidic acid binding, pho...
Does Knockout of Slc25a3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Slc25a3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Slc25a3 (solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial phosphate ion transmembrane transport, phosphate ion transmembrane transport, proton transmembrane transport; MF: ph...
Does Knockout of Champ1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Champ1
cell proliferation
Mouse kidney carcinoma cell
Gene: Champ1 (chromosome alignment maintaining phosphoprotein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: attachment of mitotic spindle microtubules to kinetochore, protein localization to kinetochore, protein localization to microtubule, sister chromatid biorienta...
Does Knockout of Nup188 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Nup188
cell proliferation
Melanoma Cell Line
Gene: Nup188 (nucleoporin 188) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA export from nucleus, mRNA transport, nucleocytoplasmic transport, protein import into nucleus, protein transport; MF: structural constituent of nuclear pore; CC: nuclear envelope, nuclear p...
Does Knockout of Cnksr1 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Cnksr1
protein/peptide distribution
myoblast cell line
Gene: Cnksr1 (connector enhancer of kinase suppressor of Ras 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Ras protein signal transduction, Rho protein signal transduction; MF: protein-macromolecule adaptor activity; CC: cell cortex Pathways: MAP2K and MAPK ...
Does Knockout of Defa22 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Defa22
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Defa22 (defensin, alpha, 22) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, defense response, defense response to Gram-negative bacterium, defense response to G...
Does Knockout of Cxxc5 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Cxxc5
response to virus
Embryonic Fibroblast Cell Line
Gene: Cxxc5 (CXXC finger 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, regulation of generation of precursor metabolites and energy; MF: DNA binding, DNA-binding transcription factor binding, metal ion bindin...
Does Knockout of Dact3 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Dact3
cell viability
Immortal mouse chromaffin cells
Gene: Dact3 (dishevelled-binding antagonist of beta-catenin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, negative regulation of Wnt signaling pathway, negative regulation of canonical Wnt signaling pathway, negative regulation of cell growth, ...
Does Knockout of Tube1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Tube1
cell proliferation
Embryonic Stem Cell Line
Gene: Tube1 (tubulin, epsilon 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule cytoskeleton organization, microtubule-based process, mitotic cell cycle; MF: GTP binding, nucleotide binding, protein binding, structural constituent of cytoskeleton; CC: centros...
Does Knockout of Dcdc2c in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Dcdc2c
protein/peptide accumulation
Embryonic Cell Line
Gene: Dcdc2c (doublecortin domain containing 2C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, intracellular signal transduction; CC: cell projection, cilium, cytoplasm, microtubule, microtubule organizing center, motile cilium, sperm flagellum ...