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Does Knockout of Mrpl33 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Mrpl33
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mrpl33 (mitochondrial ribosomal protein L33) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; CC: cytosol, mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, ribonucleoprotein complex, ribosome ...
Does Knockout of Taar9 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Taar9
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Taar9 (trace amine-associated receptor 9) Type: protein-coding Summary: Enables trace-amine receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway. Is active in plasma membrane. Is expressed in olfactory epithelium. Orthologous to human TAAR9 (trac...
Does Knockout of Slc16a12 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Slc16a12
protein/peptide accumulation
Embryonic Cell Line
Gene: Slc16a12 (solute carrier family 16 (monocarboxylic acid transporters), member 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: creatine transmembrane transport, creatinine metabolic process, transmembrane transport; MF: creatine transmembrane transporter activity...
Does Knockout of Gabpa in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Gabpa
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gabpa (GA repeat binding protein, alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blastocyst formation, cell differentiation, in utero embryonic development, negative regulation of megakaryocyte differentiation, negative regulation of transcription by RNA pol...
Does Knockout of Cdc45 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Cdc45
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cdc45 (cell division cycle 45) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, DNA replication initiation, double-strand break repair via break-induced replication, mitotic DNA replication preinitiation complex assembly; MF: DNA replication origin b...
Does Knockout of Tpm1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Tpm1
cell proliferation
Mouse kidney carcinoma cell
Gene: Tpm1 (tropomyosin 1, alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament capping, actin filament organization, cardiac muscle contraction, in utero embryonic development, muscle filament sliding, negative regulation of cell migration, negative regu...
Does Knockout of Mrpl12 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Mrpl12
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Mrpl12 (mitochondrial ribosomal protein L12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial transcription, mitochondrial translation, positive regulation of DNA-templated transcription, translation; MF: mRNA binding, structural constituent of ribosome...
Does Knockout of Mbp in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Mbp
cell proliferation
Mouse kidney carcinoma cell
Gene: Mbp (myelin basic protein) Type: protein-coding Summary: The protein encoded by the classic Mbp gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, Mbp-related transcripts are also present in the bone marrow and the immune system. ...
Does Knockout of Nudt1 in Lymphoma Cell Line causally result in response to chemicals?
0
1,525
Knockout
Nudt1
response to chemicals
Lymphoma Cell Line
Gene: Nudt1 (nudix hydrolase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA protection, purine nucleoside catabolic process; MF: 2-hydroxy-ATP hydrolase activity, 2-hydroxy-dATP hydrolase activity, 5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity,...
Does Knockout of Mpst in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Mpst
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Mpst (mercaptopyruvate sulfurtransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: hydrogen sulfide biosynthetic process, kidney development, liver development, spinal cord development, transsulfuration; MF: 3-mercaptopyruvate sulfurtransferase activity, iden...
Does Knockout of Msh5 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Msh5
cell proliferation
Melanoma Cell Line
Gene: Msh5 (mutS homolog 5) Type: protein-coding Summary: This gene encodes a member of the MutS family of proteins that play critical roles in DNA mismatch repair and meiotic homologous recombination processes. Mice lacking the encoded protein are viable but sterile, with severe defects in spermatogene...
Does Knockout of Ddx42 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Ddx42
cell proliferation
Embryonic Stem Cell Line
Gene: Ddx42 (DEAD box helicase 42) Type: protein-coding Summary: No summary available. Gene Ontology: BP: U2-type prespliceosome assembly, intracellular protein localization, regulation of apoptotic process; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase ...
Does Knockout of Rprm in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Rprm
cell proliferation
Melanoma Cell Line
Gene: Rprm (reprimo, TP53 dependent G2 arrest mediator candidate) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of cell cycle, regulation of mitotic cell cycle; CC: cytoplasm, membrane Pathways: p53 signaling pathway - Mus musculus (mouse) U...
Does Knockout of Zer1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Zer1
cell proliferation
Mouse kidney carcinoma cell
Gene: Zer1 (zyg-11 related, cell cycle regulator) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein quality control for misfolded or incompletely synthesized proteins; CC: Cul2-RING ub...
Does Knockout of Nmt1 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Nmt1
cell cycle progression
breast epithelium
Gene: Nmt1 (N-myristoyltransferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: N-terminal peptidyl-glycine N-myristoylation, cellular response to nutrient levels, in utero embryonic development, ketone metabolic process, positive regulation of TORC1 signaling, posi...
Does Knockout of Supt20 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Supt20
protein/peptide distribution
myoblast cell line
Gene: Supt20 (SPT20 SAGA complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: gastrulation, positive regulation of DNA-templated transcription, positive regulation of gluconeogenesis, positive regulation of transcription by RNA polymerase II, regulation of D...
Does Knockout of Vmn1r51 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Vmn1r51
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Vmn1r51 (vomeronasal 1 receptor 51) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromone ...
Does Knockout of Setd7 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Setd7
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Setd7 (SET domain containing (lysine methyltransferase) 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, chromatin organization, chromatin remodeling, heterochromatin organization, methylation, negative regulation of DNA repair, peptidyl-lysin...
Does Knockout of Tk1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Tk1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Tk1 (thymidine kinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA biosynthetic process, DNA synthesis involved in mitotic DNA replication, deoxyribonucleoside monophosphate biosynthetic process, protein homotetramerization, thymidine biosynthetic process,...
Does Knockout of Anapc4 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Anapc4
response to chemicals
Pancreatic Cancer Cell Line
Gene: Anapc4 (anaphase promoting complex subunit 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anaphase-promoting complex-dependent catabolic process, cell division, protein K11-linked ubiquitination, protein K48-linked ubiquitination, protein branched polyubiquitina...
Does Knockout of Eif4g3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Eif4g3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Eif4g3 (eukaryotic translation initiation factor 4 gamma, 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of meiosis I, positive regulation of translation, regulation of translation, spermatid development, spermatogenesis, translation, transla...
Does Knockout of Uspl1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Uspl1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Uspl1 (ubiquitin specific peptidase like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Cajal body organization, blastocyst formation, cell population proliferation, protein desumoylation, proteolysis, snRNA transcription; MF: SUMO binding, cysteine-type peptida...
Does Knockout of Med6 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Med6
phagocytosis
macrophage
Gene: Med6 (mediator complex subunit 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, positive regulation of transcription by RNA polymerase II, positive regulation of transcription elongation by RNA polymerase II, posit...
Does Knockout of Atg5 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,288
Knockout
Atg5
cell proliferation
Mouse kidney carcinoma cell
Gene: Atg5 (autophagy related 5) Type: protein-coding Summary: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic...
Does Knockout of Rps4x in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Rps4x
protein/peptide accumulation
Embryonic Cell Line
Gene: Rps4x (ribosomal protein S4, X-linked) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, positive regulation of cell population proliferation, positive regulation of translation, ribosomal small subunit biogenesis, translation; MF: RNA binding...
Does Knockout of Slc30a9 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Slc30a9
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Slc30a9 (solute carrier family 30 (zinc transporter), member 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular zinc ion homeostasis, monoatomic cation transmembrane transport, monoatomic cation transport, monoatomic ion transport, positive regulation ...
Does Knockout of Cebpe in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Cebpe
cell proliferation
Embryonic Stem Cell Line
Gene: Cebpe (CCAAT/enhancer binding protein epsilon) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, cellular response to lipopolysaccharide, granulocyte differentiation, macrophage differentiation, myeloid cell differentiation, phagocytosis, ...
Does Knockout of B4galnt3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
B4galnt3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: B4galnt3 (beta-1,4-N-acetyl-galactosaminyl transferase 3) Type: protein-coding Summary: No summary available. Gene Ontology: MF: N-acetyl-beta-glucosaminyl-derivative 4-beta-N-acetylgalactosaminyltransferase activity, acetylgalactosaminyltransferase activity, glucuronosyl-N-acetylgalactos...
Does Knockout of Rbbp8 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Rbbp8
autophagy
Embryonic Fibroblast Cell Line
Gene: Rbbp8 (retinoblastoma binding protein 8, endonuclease) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA double-strand break processing involved in repair via single-strand annealing, DNA repair, DNA strand resection involved in replication fo...
Does Knockout of Kansl2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Kansl2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Kansl2 (KAT8 regulatory NSL complex subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, positive regulation of DNA-templated transcription; CC: NSL complex, actin cytoskeleton, cytosol, histone acetyltransferase complex, mitochondrion,...
Does Knockout of Irf1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Irf1
autophagy
Embryonic Fibroblast Cell Line
Gene: Irf1 (interferon regulatory factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CD8-positive, alpha-beta T cell differentiation, apoptotic process, canonical NF-kappaB signal transduction, cellular response to interferon-beta, cellular response to interleukin-...
Does Knockout of Agr2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Agr2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Agr2 (anterior gradient 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell chemotaxis, digestive tract morphogenesis, endoplasmic reticulum unfolded protein response, inflammatory response, lung goblet cell differentiation, mucus secretion, positive regulation ...
Does Knockout of Golga4 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Golga4
protein/peptide distribution
myoblast cell line
Gene: Golga4 (golgin A4) Type: protein-coding Summary: Predicted to enable small GTPase binding activity. Predicted to be involved in Golgi to plasma membrane protein transport and positive regulation of axon extension. Located in Golgi apparatus. Is expressed in several structures, including alimentary...
Does Knockout of Pmp22 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Pmp22
autophagy
Embryonic Fibroblast Cell Line
Gene: Pmp22 (peripheral myelin protein 22) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Schwann cell development, Schwann cell differentiation, Schwann cell migration, actin cytoskeleton organization, adult locomotory behavior, adult walking behavior, aggresome assembl...
Does Knockout of Hbb-bs in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Hbb-bs
protein/peptide distribution
myoblast cell line
Gene: Hbb-bs (hemoglobin, beta adult s chain) Type: protein-coding Summary: This gene encodes a beta polypeptide chain found in adult hemoglobin, which consists of a tetramer of two alpha chains and two beta chains, and which functions in the transport of oxygen to various peripheral tissues. This gene ...
Does Knockout of Lamtor1 in Regulatory T cell causally result in cell proliferation?
1
2,127
Knockout
Lamtor1
cell proliferation
Regulatory T cell
Gene: Lamtor1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: TORC1 signaling, autophagosome assembly, cellular response to amino acid stimulus, cellular response to nutrient levels, cholesterol homeostasis, cy...
Does Knockout of Lrp2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Lrp2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Lrp2 (low density lipoprotein receptor-related protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: alcohol metabolic process, amyloid-beta clearance, aorta development, cardiac septum development, cell population proliferation, cellular response to growth fac...
Does Knockout of Lypd8 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Lypd8
cell cycle progression
breast epithelium
Gene: Lypd8 (LY6/PLAUR domain containing 8) Type: protein-coding Summary: This gene encodes a member of the Ly6/PLAUR family of cysteine-rich proteins that plays an important role in the protection of colonic epithelium from flagellated microbiota. The encoded protein undergoes proteolytic processing to...
Does Knockout of Fam53a in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Fam53a
protein/peptide distribution
myoblast cell line
Gene: Fam53a (family with sequence similarity 53, member A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein import into nucleus; CC: nucleus Pathways: UniProt: E9PV82 Entrez ID: 74504
Does Knockout of Stmnd1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Stmnd1
cell proliferation
Mouse kidney carcinoma cell
Gene: Stmnd1 (stathmin domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q6P3A1 Entrez ID: 380842
Does Knockout of Il3 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Il3
cell proliferation
Regulatory T cell
Gene: Il3 (interleukin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway via STAT, cytokine-mediated signaling pathway, embryonic hemopoiesis, extrinsic apoptotic signaling pathway in absence of ligand, hemopoiesis, immune response...
Does Knockout of Polr2e in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Polr2e
tumorigenicity
Colonic Cancer Cell Line
Gene: Polr2e (polymerase (RNA) II (DNA directed) polypeptide E) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, tRNA transcription by RNA polymerase III, transcription by RNA polymerase II, transcription elongation by RNA polymerase I; MF: DNA...
Does Knockout of Pcdh9 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Pcdh9
cell proliferation
Mouse kidney carcinoma cell
Gene: Pcdh9 (protocadherin 9) Type: protein-coding Summary: This gene encodes a member of the protocadherin family, and cadherin superfamily, of transmembrane proteins containing cadherin domains. These proteins mediate cell adhesion in neural tissues in the presence of calcium. The encoded protein may ...
Does Knockout of Exosc10 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Exosc10
cell proliferation
Embryonic Stem Cell Line
Gene: Exosc10 (exosome component 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CUT catabolic process, DNA damage response, DNA repair, RNA catabolic process, RNA processing, TRAMP-dependent tRNA surveillance pathway, exonucleolytic trimming to generate mature 3'-end...
Does Knockout of 9330182O14Rik in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
9330182O14Rik
cell proliferation
Embryonic Stem Cell Line
Gene: 9330182O14Rik (RIKEN cDNA 9330182O14 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: J3QNB2 Entrez ID: 328531
Does Knockout of Kdm1b in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Kdm1b
cell proliferation
Mouse kidney carcinoma cell
Gene: Kdm1b (lysine (K)-specific demethylase 1B) Type: protein-coding Summary: Enables FAD-dependent H3K4me/H3K4me3 demethylase activity; flavin adenine dinucleotide binding activity; and zinc ion binding activity. Involved in genomic imprinting. Acts upstream of or within epigenetic programing of femal...
Does Knockout of Rpia in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Rpia
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rpia (ribose 5-phosphate isomerase A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-ribose metabolic process, pentose-phosphate shunt, pentose-phosphate shunt, non-oxidative branch; MF: carbohydrate binding, identical protein binding, isomerase activity, monosac...
Does Knockout of Tirap in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Tirap
cell proliferation
Colonic Cancer Cell Line
Gene: Tirap (toll-interleukin 1 receptor (TIR) domain-containing adaptor protein) Type: protein-coding Summary: Enables several functions, including Toll-like receptor 2 binding activity; identical protein binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in several ...
Does Knockout of Pi4k2a in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Pi4k2a
cell proliferation
Colonic Cancer Cell Line
Gene: Pi4k2a (phosphatidylinositol 4-kinase type 2 alpha) Type: protein-coding Summary: Predicted to enable 1-phosphatidylinositol 4-kinase activity; AP-3 adaptor complex binding activity; and ATP binding activity. Predicted to be involved in several processes, including basophil degranulation; endosome...
Does Knockout of Hpn in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Hpn
protein/peptide distribution
myoblast cell line
Gene: Hpn (hepsin) Type: protein-coding Summary: This gene encodes a type II transmembrane serine protease that may function in diverse processes, including regulation of cell growth. Deficiency in this gene results in hearing loss. The protein is cleaved into a catalytic serine protease chain and a non...
Does Knockout of Dnmt3b in Lung Cancer Cell Line causally result in tumorigenicity?
1
1,089
Knockout
Dnmt3b
tumorigenicity
Lung Cancer Cell Line
Gene: Dnmt3b (DNA methyltransferase 3B) Type: protein-coding Summary: This is one of two related genes encoding de novo DNA methyltransferases, which are responsible for the establishment of DNA methylation patterns in embryos. Loss of function of this gene results in severe developmental defects and lo...
Does Knockout of Mxra8 in Pancreatic Cell Line causally result in cell proliferation?
0
2,193
Knockout
Mxra8
cell proliferation
Pancreatic Cell Line
Gene: Mxra8 (matrix-remodelling associated 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell differentiation, establishment of glial blood-brain barrier; CC: anchoring junction, bicellular tight junction, cell projection, cell surface, ciliary membran...
Does Knockout of Rai1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Rai1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Rai1 (retinoic acid induced 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: circadian regulation of gene expression, negative regulation of multicellular organism growth, positive regulation of DNA-templated transcription, regulation of transcription by RNA polym...
Does Knockout of Elac2 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Elac2
cell proliferation
Mouse kidney carcinoma cell
Gene: Elac2 (elaC ribonuclease Z 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial tRNA 3'-end processing, tRNA processing; MF: 3'-tRNA processing endoribonuclease activity, endonuclease activity, hydrolase activity, metal ion binding, nuclease activity, tR...
Does Knockout of Raf1 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Raf1
protein/peptide distribution
myoblast cell line
Gene: Raf1 (v-raf-leukemia viral oncogene 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERBB2-ERBB3 signaling pathway, MAPK cascade, Schwann cell development, cell differentiation, death-inducing signaling complex assembly, face development, insulin receptor signalin...
Does Knockout of Pou5f1 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Pou5f1
protein/peptide distribution
Microglial Cell Line
Gene: Pou5f1 (POU domain, class 5, transcription factor 1) Type: protein-coding Summary: The protein encoded by this gene belongs to the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathw...
Does Knockout of Dctn3 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,287
Knockout
Dctn3
cell proliferation
Mouse kidney carcinoma cell
Gene: Dctn3 (dynactin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, cytoskeleton-dependent cytokinesis, microtubule-based process; CC: centrosome, chromosome, chromosome, centromeric region, cleavage furrow, cytoplasm, cytoskeleton, cytosol, dynactin c...
Does Knockout of Gtf2h4 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Gtf2h4
cell proliferation
Embryonic Stem Cell Line
Gene: Gtf2h4 (general transcription factor II H, polypeptide 4) Type: protein-coding Summary: This gene encodes a subunit of the general transcription factor multiprotein complex that plays roles in basal transcription, DNA repair and cell cycle control. [provided by RefSeq, Dec 2014]. Gene Ont...
Does Knockout of Itch in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Itch
cell proliferation
Mouse kidney carcinoma cell
Gene: Itch (itchy, E3 ubiquitin protein ligase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CXCL12-activated CXCR4 signaling pathway, apoptotic process, cytoplasmic pattern recognition receptor signaling pathway, defense response to virus, immune system process, innat...
Does Knockout of Trim80 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Trim80
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Trim80 (tripartite motif-containing 80) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, immune system process, innate immune response; MF: metal ion binding, molecular_function, zinc ion binding Pathways: UniProt: Q3V061 ...
Does Knockout of Arap1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Arap1
protein/peptide distribution
myoblast cell line
Gene: Arap1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of stress fiber assembly, photoreceptor cell maintenance, positive regulation of DNA-templated transcription, positive regulation of...
Does Knockout of Anapc7 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Anapc7
cell proliferation
Embryonic Stem Cell Line
Gene: Anapc7 (anaphase promoting complex subunit 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anaphase-promoting complex-dependent catabolic process, brain development, cell division, positive regulation of mitotic metaphase/anaphase transition, protein K11-linked u...
Does Knockout of Gpr20 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Gpr20
cell proliferation
Mouse kidney carcinoma cell
Gene: Gpr20 (G protein-coupled receptor 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane, receptor complex Pathways: G alp...
Does Knockout of Kpna2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Kpna2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Kpna2 (karyopherin subunit alpha 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NLS-bearing protein import into nucleus, entry of viral genome into host nucleus through nuclear pore complex via importin, non-canonical NF-kappaB signal transduction, positive regu...
Does Knockout of Il3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Il3
cell proliferation
Mouse kidney carcinoma cell
Gene: Il3 (interleukin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway via STAT, cytokine-mediated signaling pathway, embryonic hemopoiesis, extrinsic apoptotic signaling pathway in absence of ligand, hemopoiesis, immune response...
Does Knockout of Mir434 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Mir434
response to chemicals
Pancreatic Cancer Cell Line
Gene: Mir434 (microRNA 434) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I...
Does Knockout of Gimap4 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Gimap4
cell proliferation
Mouse kidney carcinoma cell
Gene: Gimap4 (GTPase, IMAP family member 4) Type: protein-coding Summary: This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. This gene exists within a cluster of other related genes located on mouse...
Does Knockout of Mettl17 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Mettl17
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Mettl17 (methyltransferase like 17) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial small ribosomal subunit assembly, ribosomal small subunit biogenesis, translation; MF: 4 iron, 4 sulfur cluster binding, S-adenosyl-L-methionine binding, iron-sulfur cl...
Does Knockout of Sumf2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Sumf2
cell proliferation
Mouse kidney carcinoma cell
Gene: Sumf2 (sulfatase modifying factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: enzyme inhibitor activity, identical protein binding, metal ion binding, protein binding; CC: endoplasmic reticulum, endoplasmic reticulum lumen Pathways: Gamma carboxylati...
Does Knockout of Pard3 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Pard3
protein/peptide accumulation
Embryonic Cell Line
Gene: Pard3 (par-3 family cell polarity regulator) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apical constriction, bicellular tight junction assembly, cell adhesion, cell differentiation, cell division, cell-cell adhesion, centrosome localization, establishment of ce...
Does Knockout of Bcorl1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Bcorl1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Bcorl1 (BCL6 co-repressor-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, negative regulation of transcription by RNA polymerase II; CC: nucleoplasm, nucleus, plasma membrane Pathways: UniProt: A2AQH4 Entrez...
Does Knockout of Tmem41b in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Tmem41b
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Tmem41b (transmembrane protein 41B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, autophagy, host-mediated perturbation of viral RNA genome replication, intracellular lipid transport, lipid transport, nervous system development, plasma memb...
Does Knockout of Tm4sf5 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Tm4sf5
cell proliferation
Colonic Cancer Cell Line
Gene: Tm4sf5 (transmembrane 4 superfamily member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of G1/S transition of mitotic cell cycle; MF: arginine binding; CC: lysosomal membrane, membrane, plasma membrane Pathways: UniProt: Q9D8G1, Q...
Does Knockout of Pten in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Pten
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Pten (phosphatase and tensin homolog) Type: protein-coding Summary: This gene encodes a phosphatase with dual activity against phospholipids and proteins, and acts as a tumor-suppressor. The protein contains four structural domains, a PIP2-binding domain, a catalytic tensin-type phosphatase domain...
Does Knockout of Dpys in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Dpys
protein/peptide distribution
myoblast cell line
Gene: Dpys (dihydropyrimidinase) Type: protein-coding Summary: Enables dihydropyrimidinase activity and phosphoprotein binding activity. Involved in pyrimidine nucleoside monophosphate catabolic process. Is active in cytosol. Is expressed in cranium. Human ortholog(s) of this gene implicated in dihydrop...
Does Knockout of Abca8a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Abca8a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Abca8a (ATP-binding cassette, sub-family A member 8a) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cholesterol efflux, cholesterol transport, lipid transport, positive regulation of cholesterol efflux, regulation of cholesterol efflux, sphingomyelin biosynthetic ...
Does Knockout of Gm12886 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Gm12886
cell proliferation
Colonic Cancer Cell Line
Gene: Gm12886 (predicted gene 12886) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: B1AZM5 Entrez ID: 666921
Does Knockout of Gramd1a in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Gramd1a
protein/peptide accumulation
Regulatory T cell
Gene: Gramd1a (GRAM domain containing 1A) Type: protein-coding Summary: Enables cholesterol binding activity and cholesterol transfer activity. Involved in cellular response to cholesterol. Located in endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; and plasma membrane...
Does Knockout of Agxt2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Agxt2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Agxt2 (alanine-glyoxylate aminotransferase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-alanine catabolic process, by transamination, N(omega),N(omega)-dimethyl-L-arginine catabolic process, glycine biosynthetic process, by transamination of glyoxylate, glyo...
Does Knockout of Kcnj16 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Kcnj16
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Kcnj16 (potassium inwardly-rectifying channel, subfamily J, member 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion import across plasma membrane, potassium ion transmembrane transpor...
Does Knockout of Atg4c in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Atg4c
cell proliferation
Melanoma Cell Line
Gene: Atg4c (autophagy related 4C, cysteine peptidase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aggrephagy, autophagosome assembly, autophagy, mitophagy, piecemeal microautophagy of the nucleus, protein delipidation, protein processing, protein transport, proteolys...
Does Knockout of Rcor1 in Lymphoma Cell Line causally result in response to chemicals?
0
1,549
Knockout
Rcor1
response to chemicals
Lymphoma Cell Line
Gene: Rcor1 (REST corepressor 1) Type: protein-coding Summary: Enables chromatin binding activity; enzyme binding activity; and transcription corepressor activity. Involved in erythrocyte differentiation; negative regulation of gene expression; and positive regulation of megakaryocyte differentiation. P...
Does Knockout of Rfk in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Rfk
protein/peptide distribution
myoblast cell line
Gene: Rfk (riboflavin kinase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: FMN biosynthetic process, apoptotic process, flavin adenine dinucleotide biosynthetic process, reactive oxygen species metabolic process, riboflavin biosynthetic process, riboflavin metabolic pr...
Does Knockout of Pdlim3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Pdlim3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Pdlim3 (PDZ and LIM domain 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, actin filament organization, heart development, muscle structure development; MF: actin binding, actinin binding, cytoskeletal protein binding, metal ion b...
Does Knockout of 4933405O20Rik in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
4933405O20Rik
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: 4933405O20Rik (RIKEN cDNA 4933405O20 gene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: isocitrate metabolic process, tricarboxylic acid cycle; MF: ATP binding, magnesium ion binding, metal ion binding, nucleotide binding; CC: mitochondrion Pathways: Cit...
Does Knockout of Kazn in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Kazn
protein/peptide distribution
myoblast cell line
Gene: Kazn (kazrin, periplakin interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: CC: anchoring junction, cornified envelope, cytoplasm, cytoskeleton, cytosol, desmosome, nuclear speck, nucleoplasm, nucleus Pathways: Developmental Biology, Formation...
Does Knockout of Nup62 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Nup62
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nup62 (nucleoporin 62) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA export from nucleus, cell migration, cell surface receptor signaling pathway, cellular senescence, centriole assembly, centrosome cycle, mRNA transport, mitotic centrosome separation, mitotic...
Does Knockout of Rnf40 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Rnf40
cell proliferation
Embryonic Stem Cell Line
Gene: Rnf40 (ring finger protein 40) Type: protein-coding Summary: Predicted to enable several functions, including enzyme binding activity; protein homodimerization activity; and syntaxin-1 binding activity. Predicted to be involved in positive regulation of macromolecule metabolic process and ubiquiti...
Does Knockout of Ascc3 in Lymphoma Cell Line causally result in response to chemicals?
1
1,543
Knockout
Ascc3
response to chemicals
Lymphoma Cell Line
Gene: Ascc3 (activating signal cointegrator 1 complex subunit 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CAT tailing, DNA alkylation repair, DNA damage response, DNA repair, protein monoubiquitination, protein ufmylation, rescue of stalled ribosome, ribosome disas...
Does Knockout of Rad50 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Rad50
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rad50 (RAD50 double strand break repair protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA double-strand break processing, DNA recombination, DNA repair, DNA strand resection involved in replication fork processing, R-loop processing, ...
Does Knockout of Mybpc3 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Mybpc3
autophagy
Embryonic Fibroblast Cell Line
Gene: Mybpc3 (myosin binding protein C, cardiac) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cardiac muscle contraction, cell adhesion, heart morphogenesis, muscle contraction, myosin filament assembly, regulation of heart contraction, regulation of heart rate, sarcom...
Does Knockout of Vmn1r81 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Vmn1r81
response to virus
Microglial Cell Line
Gene: Vmn1r81 (vomeronasal 1 receptor 81) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromone ...
Does Knockout of Prrt1 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Prrt1
protein/peptide distribution
myoblast cell line
Gene: Prrt1 (proline-rich transmembrane protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular protein localization, learning or memory, long-term synaptic depression, long-term synaptic potentiation, protein localization to cell surface, protein phospho...
Does Knockout of Tmem64 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Tmem64
cell proliferation
Embryonic Stem Cell Line
Gene: Tmem64 (transmembrane protein 64) Type: protein-coding Summary: Involved in negative regulation of canonical Wnt signaling pathway; negative regulation of osteoblast differentiation; and positive regulation of fat cell differentiation. Acts upstream of or within several processes, including positi...
Does Knockout of Slc35a2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Slc35a2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Slc35a2 (solute carrier family 35 (UDP-galactose transporter), member A2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: UDP-galactose transmembrane transport, pyrimidine nucleotide-sugar transmembrane transport; MF: UDP-galactose transmembrane transporter activity...
Does Knockout of Scnm1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Scnm1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Scnm1 (sodium channel modifier 1) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Vmn1r16 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Vmn1r16
cell proliferation
Embryonic Stem Cell Line
Gene: Vmn1r16 (vomeronasal 1 receptor 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromone ...
Does Knockout of Haus2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Haus2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Haus2 (HAUS augmin-like complex, subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, centrosome cycle, microtubule nucleation, microtubule organizing center organization, spindle assembly; CC: HAUS complex, centrosome, cytoplasm, cytoskeleton, ...
Does Knockout of B4galnt1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
B4galnt1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: B4galnt1 (beta-1,4-N-acetyl-galactosaminyl transferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate derivative biosynthetic process, determination of adult lifespan, ganglioside biosynthetic process, glycosphingolipid biosynthetic process, glycosp...
Does Knockout of Ascl3 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Ascl3
cell viability
Immortal mouse chromaffin cells
Gene: Ascl3 (achaete-scute family bHLH transcription factor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, epithelium development, negative regulation of transcription by RNA polymerase II, positive regulation of transcription by RNA polymera...