prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of Tyk2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 161 | Knockout | Tyk2 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Tyk2 (tyrosine kinase 2)
Type: protein-coding
Summary: Predicted to enable growth hormone receptor binding activity; non-membrane spanning protein tyrosine kinase activity; and type 1 angiotensin receptor binding activity. Involved in cell population proliferation and positive regulation of T cell... |
Does Knockout of Cyp2d12 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 688 | Knockout | Cyp2d12 | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Cyp2d12 (cytochrome P450, family 2, subfamily d, polypeptide 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: arachidonate metabolic process, xenobiotic metabolic process; MF: anandamide 11,12 epoxidase activity, anandamide 14,15 epoxidase activity, anandamide 8,... |
Does Knockout of Syt6 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,286 | Knockout | Syt6 | cell proliferation | Mouse kidney carcinoma cell | Gene: Syt6 (synaptotagmin VI)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: acrosomal vesicle exocytosis, acrosome reaction, chemical synaptic transmission, postsynaptic dense core vesicle exocytosis, regulation of calcium ion-dependent exocytosis, vesicle-mediated tran... |
Does Knockout of Phf12 in Mouse kidney carcinoma cell causally result in cell proliferation? | 1 | 1,289 | Knockout | Phf12 | cell proliferation | Mouse kidney carcinoma cell | Gene: Phf12 (PHD finger protein 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II; MF: metal ion binding, phosphatidylinositol binding, protein binding, transcr... |
Does Knockout of Rtp1 in breast epithelium causally result in cell cycle progression? | 0 | 1,468 | Knockout | Rtp1 | cell cycle progression | breast epithelium | Gene: Rtp1 (receptor transporter protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: detection of chemical stimulus involved in sensory perception of bitter taste, protein insertion into membrane, protein targeting to membrane; MF: metal ion binding, olfactory rece... |
Does Knockout of Gtf2h2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,262 | Knockout | Gtf2h2 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Gtf2h2 (general transcription factor II H, polypeptide 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, DNA-templated transcription, nucleotide-excision repair, regulation of transcription by RNA polymerase II, transcription by RNA... |
Does Knockout of Atrip in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 1,264 | Knockout | Atrip | cell proliferation | Colonic Cancer Cell Line | Gene: Atrip (ATR interacting protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage checkpoint signaling, DNA damage response, DNA repair, nucleobase-containing compound metabolic process, regulation of double-strand break repair; MF: K63-linked polyubiquitin... |
Does Knockout of Mtmr14 in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation? | 1 | 1,522 | Knockout | Mtmr14 | protein/peptide accumulation | Embryonic Fibroblast Cell Line | Gene: Mtmr14 (myotubularin related protein 14)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: hydrolase activity, phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity, phosphatidylinositol-3-phosphate phosphatase activity; CC: cytoplasm, perinuclear region of cyt... |
Does Knockout of Nop58 in Immortal mouse chromaffin cells causally result in cell viability? | 1 | 2,469 | Knockout | Nop58 | cell viability | Immortal mouse chromaffin cells | Gene: Nop58 (NOP58 ribonucleoprotein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ribosomal small subunit biogenesis, ribosome biogenesis, snoRNA localization; MF: ATPase binding, RNA binding, TFIID-class transcription factor complex binding, snoRNA binding; CC: Cajal... |
Does Knockout of Ei24 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 83 | Knockout | Ei24 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Ei24 (etoposide induced 2.4 mRNA)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, autophagy, cellular response to UV-C, intrinsic apoptotic signaling pathway in response to DNA damage, macroautophagy, negative regulation of cell growth, negative r... |
Does Knockout of Alg5 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 2,307 | Knockout | Alg5 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: Alg5 (ALG5 dolichyl-phosphate beta-glucosyltransferase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: determination of left/right symmetry, dolichol-linked oligosaccharide biosynthetic process, protein N-linked glycosylation, protein glycosylation; MF: dolichyl-ph... |
Does Knockout of Zfp37 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,264 | Knockout | Zfp37 | cell proliferation | Colonic Cancer Cell Line | Gene: Zfp37 (zinc finger protein 37)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcripti... |
Does Knockout of Ankle1 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 2,477 | Knockout | Ankle1 | cell proliferation | Embryonic Stem Cell Line | Gene: Ankle1 (ankyrin repeat and LEM domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, determination of adult lifespan, double-strand break repair via homologous recombination, erythrocyte maturation, negative regulation... |
Does Knockout of Serpina12 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,273 | Knockout | Serpina12 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Serpina12 (serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of gluconeogenesis, negative regulation of lipid biosynthetic process, positive regulat... |
Does Knockout of Rev1 in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 2,477 | Knockout | Rev1 | cell proliferation | Embryonic Stem Cell Line | Gene: Rev1 (REV1, DNA directed polymerase)
Type: protein-coding
Summary: Enables deoxycytidyl transferase activity. Acts upstream of or within error-prone translesion synthesis. Predicted to be located in nucleus. Orthologous to human REV1 (REV1 DNA directed polymerase). [provided by Alliance of Genome ... |
Does Knockout of Dnlz in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 1 | 1,267 | Knockout | Dnlz | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Dnlz (DNL-type zinc finger)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chaperone-mediated protein complex assembly, protein folding, protein import into mitochondrial matrix, protein stabilization; MF: metal ion binding, protein folding chaperone, protein-foldi... |
Does Knockout of Sc5d in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,290 | Knockout | Sc5d | cell proliferation | Mouse kidney carcinoma cell | Gene: Sc5d (sterol-C5-desaturase)
Type: protein-coding
Summary: Predicted to enable C-5 sterol desaturase activity and delta7-sterol 5(6)-desaturase activity. Predicted to be involved in cholesterol biosynthetic process via lathosterol and negative regulation of ferroptosis. Predicted to be active in en... |
Does Knockout of Hcfc1r1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 82 | Knockout | Hcfc1r1 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Hcfc1r1 (host cell factor C1 regulator 1 (XPO1-dependent))
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: cytoplasm, nucleoplasm, nucleus
Pathways:
UniProt: Q9CYQ5
Entrez ID: 353502 |
Does Knockout of Shq1 in Melanoma Cell Line causally result in cell proliferation? | 1 | 1,270 | Knockout | Shq1 | cell proliferation | Melanoma Cell Line | Gene: Shq1 (SHQ1 homolog (S. cerevisiae))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: box H/ACA snoRNP assembly, positive regulation of TORC1 signaling, protein-RNA complex assembly, regulation of androgen receptor signaling pathway; CC: cytoplasm, cytosol, nucleoplas... |
Does Knockout of Tal2 in Embryonic Cell Line causally result in protein/peptide accumulation? | 1 | 1,440 | Knockout | Tal2 | protein/peptide accumulation | Embryonic Cell Line | Gene: Tal2 (T cell acute lymphocytic leukemia 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: midbrain development, multicellular organism growth, post-embryonic development, regulation of transcription by RNA polymerase II, thalamus development; MF: DNA binding, DNA-b... |
Does Knockout of Tfdp1 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,288 | Knockout | Tfdp1 | cell proliferation | Mouse kidney carcinoma cell | Gene: Tfdp1 (transcription factor Dp 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: anoikis, epidermis development, negative regulation of fat cell proliferation, positive regulation of DNA-templated transcription, positive regulation of G1/S transition of mitotic cel... |
Does Knockout of Rapgef1 in Embryonic Fibroblast Cell Line causally result in autophagy? | 1 | 1,044 | Knockout | Rapgef1 | autophagy | Embryonic Fibroblast Cell Line | Gene: Rapgef1 (Rap guanine nucleotide exchange factor (GEF) 1)
Type: protein-coding
Summary: Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within several processes, including activation of GTPase activity; negative regulation of signal transduction; and platelet-derived growth ... |
Does Knockout of Rfk in Immortal mouse chromaffin cells causally result in cell viability? | 0 | 2,469 | Knockout | Rfk | cell viability | Immortal mouse chromaffin cells | Gene: Rfk (riboflavin kinase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: FMN biosynthetic process, apoptotic process, flavin adenine dinucleotide biosynthetic process, reactive oxygen species metabolic process, riboflavin biosynthetic process, riboflavin metabolic pr... |
Does Knockout of Gins3 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,288 | Knockout | Gins3 | cell proliferation | Mouse kidney carcinoma cell | Gene: Gins3 (GINS complex subunit 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA replication, cellular senescence, multicellular organism growth; CC: CMG complex, GINS complex, chromosome, nucleoplasm, nucleus
Pathways: Cell Cycle, Cell Cycle, Mitotic, DN... |
Does Knockout of Smarcc1 in Melanoma Cell Line causally result in cell proliferation? | 1 | 1,270 | Knockout | Smarcc1 | cell proliferation | Melanoma Cell Line | Gene: Smarcc1 (SWI/SNF related BAF chromatin remodeling complex subunit C1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: animal organ morphogenesis, chromatin organization, chromatin remodeling, chromosome organization, insulin receptor signaling pathway, negative regu... |
Does Knockout of Stac in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 2,307 | Knockout | Stac | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: Stac (src homology three (SH3) and cysteine rich domain)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to heat, muscle contraction, positive regulation of cation channel activity, positive regulation of protein localization to plasma membrane, po... |
Does Knockout of Vps33a in Mouse kidney carcinoma cell causally result in cell proliferation? | 1 | 1,288 | Knockout | Vps33a | cell proliferation | Mouse kidney carcinoma cell | Gene: Vps33a (VPS33A CORVET/HOPS core subunit)
Type: protein-coding
Summary: Acts upstream of or within pigmentation; platelet formation; and regulation of developmental pigmentation. Located in autophagosome and lysosome. Part of CORVET complex. Is expressed in ganglia. Used to study Hermansky-Pudlak s... |
Does Knockout of Zmiz2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 165 | Knockout | Zmiz2 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Zmiz2 (zinc finger, MIZ-type containing 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of transcription by RNA polymerase II, protein sumoylation, regulation of transcription by RNA polymerase II; MF: SUMO ligase activity, metal ion binding, ... |
Does Knockout of Cwc15 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Cwc15 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Cwc15 (CWC15 spliceosome-associated protein)
Type: protein-coding
Summary: Predicted to enable RNA binding activity. Predicted to be involved in mRNA cis splicing, via spliceosome. Predicted to be located in mitochondrion and nuclear speck. Predicted to be part of Prp19 complex and U2-type catalyt... |
Does Knockout of Gna11 in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 579 | Knockout | Gna11 | cell proliferation | Embryonic Stem Cell Line | Gene: Gna11 (guanine nucleotide binding protein, alpha 11)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, action potential, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, cellular response to pH, c... |
Does Knockout of Timm8b in Colonic Cancer Cell Line causally result in tumorigenicity? | 0 | 2,181 | Knockout | Timm8b | tumorigenicity | Colonic Cancer Cell Line | Gene: Timm8b (translocase of inner mitochondrial membrane 8B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: membrane, mitochondrial inner membrane, mitochondrion
Pathways:
UniProt: P62077
Entrez ID: 30057 |
Does Knockout of Lrrc8b in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,287 | Knockout | Lrrc8b | cell proliferation | Mouse kidney carcinoma cell | Gene: Lrrc8b (leucine rich repeat containing 8 family, member B)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: aspartate transmembrane transport, cyclic-GMP-AMP transmembrane import across plasma membrane, monoatomic anion transmembrane transport, monoatomic ion transme... |
Does Knockout of Lztfl1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,267 | Knockout | Lztfl1 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Lztfl1 (leucine zipper transcription factor-like 1)
Type: protein-coding
Summary: Predicted to enable identical protein binding activity. Acts upstream of or within flagellated sperm motility and spermatogenesis. Located in cilium; cytoplasm; and manchette. Is expressed in several structures, incl... |
Does Knockout of Nle1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Nle1 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Nle1 (notchless homolog 1)
Type: protein-coding
Summary: Acts upstream of or within several processes, including chordate embryonic development; hematopoietic stem cell homeostasis; and positive regulation of canonical Wnt signaling pathway. Located in nucleolus. Is expressed in several structures... |
Does Knockout of Hsd17b12 in breast epithelium causally result in cell cycle progression? | 0 | 1,468 | Knockout | Hsd17b12 | cell cycle progression | breast epithelium | Gene: Hsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: estrogen biosynthetic process, extracellular matrix organization, fatty acid biosynthetic process, fatty acid elongation, saturated fatty acid, lipid metabolic proce... |
Does Knockout of Chtop in Embryonic Fibroblast Cell Line causally result in response to virus? | 0 | 1,133 | Knockout | Chtop | response to virus | Embryonic Fibroblast Cell Line | Gene: Chtop (chromatin target of PRMT1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin remodeling, in utero embryonic development, mRNA export from nucleus; MF: RNA binding, methyl-CpG binding, protein binding; CC: nuclear speck, nucleolus, nucleoplasm, nucleus... |
Does Knockout of Sirt6 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,280 | Knockout | Sirt6 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Sirt6 (sirtuin 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, Ras protein signal transduction, base-excision repair, cardiac muscle cell differentiation, cellular response to angiotensin... |
Does Knockout of Cnot1 in Melanoma Cell Line causally result in cell proliferation? | 1 | 1,270 | Knockout | Cnot1 | cell proliferation | Melanoma Cell Line | Gene: Cnot1 (CCR4-NOT transcription complex, subunit 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: miRNA-mediated post-transcriptional gene silencing, negative regulation of intracellular estrogen receptor signaling pathway, negative regulation of retinoic acid recep... |
Does Knockout of Ipo11 in Melanoma Cell Line causally result in cell proliferation? | 1 | 1,270 | Knockout | Ipo11 | cell proliferation | Melanoma Cell Line | Gene: Ipo11 (importin 11)
Type: protein-coding
Summary: Enables nuclear import signal receptor activity. Acts upstream of or within ribosomal protein import into nucleus. Predicted to be located in nucleoplasm. Predicted to be active in cytosol and nuclear envelope. Is expressed in several structures, i... |
Does Knockout of Galnt15 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 82 | Knockout | Galnt15 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Galnt15 (polypeptide N-acetylgalactosaminyltransferase 15)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, protein O-linked glycosylation, protein glycosylation; MF: carbohydrate binding, glycosyltransferase activity, metal ion binding, molecular... |
Does Knockout of Coq6 in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 1,264 | Knockout | Coq6 | cell proliferation | Colonic Cancer Cell Line | Gene: Coq6 (coenzyme Q6 monooxygenase)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ubiquinone biosynthetic process; MF: 2-methoxy-6-polyprenolphenol 4-hydroxylase activity, 4-hydroxy-3-all-trans-polyprenylbenzoate oxygenase activity, FAD binding, flavin adenine dinucl... |
Does Knockout of Mir703 in Embryonic Fibroblast Cell Line causally result in response to virus? | 1 | 1,133 | Knockout | Mir703 | response to virus | Embryonic Fibroblast Cell Line | Gene: Mir703 (microRNA 703)
Type: ncRNA
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I... |
Does Knockout of Vmn2r39 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,681 | Knockout | Vmn2r39 | protein/peptide distribution | myoblast cell line | Gene: Vmn2r39 (vomeronasal 2, receptor 39)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane
Pathways:
UniProt: L7N2E... |
Does Knockout of Kdm5d in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,684 | Knockout | Kdm5d | protein/peptide distribution | myoblast cell line | Gene: Kdm5d (lysine demethylase 5D)
Type: protein-coding
Summary: Predicted to enable histone H3K4me/H3K4me2/H3K4me3 demethylase activity and nuclear androgen receptor binding activity. Acts upstream of or within T cell antigen processing and presentation. Predicted to be located in fibrillar center. Pr... |
Does Knockout of Gpat3 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 579 | Knockout | Gpat3 | cell proliferation | Embryonic Stem Cell Line | Gene: Gpat3 (glycerol-3-phosphate acyltransferase 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CDP-diacylglycerol biosynthetic process, glycerol-3-phosphate metabolic process, glycerolipid metabolic process, lipid metabolic process, phospholipid biosynthetic process... |
Does Knockout of Hsf2bp in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 687 | Knockout | Hsf2bp | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Hsf2bp (heat shock transcription factor 2 binding protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: double-strand break repair involved in meiotic recombination, female meiosis I, male meiosis I, spermatogenesis; CC: chromosome, cytoplasm, cytosol, nucleoplas... |
Does Knockout of Fabp1 in breast epithelium causally result in cell cycle progression? | 0 | 1,468 | Knockout | Fabp1 | cell cycle progression | breast epithelium | Gene: Fabp1 (fatty acid binding protein 1, liver)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: D-glucose transmembrane transport, acylglycerol biosynthetic process, acylglycerol metabolic process, adult feeding behavior, aldehyde metabolic process, arachidonate metabol... |
Does Knockout of Cpd in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 2,403 | Knockout | Cpd | protein/peptide accumulation | Embryonic Cell Line | Gene: Cpd (carboxypeptidase D)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: peptide metabolic process, protein processing, proteolysis; MF: carboxypeptidase activity, hydrolase activity, metal ion binding, metallocarboxypeptidase activity, metallopeptidase activity, pe... |
Does Knockout of Chac2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 81 | Knockout | Chac2 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Chac2 (ChaC, cation transport regulator 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: glutathione catabolic process; MF: glutathione specific gamma-glutamylcyclotransferase activity, lyase activity; CC: cytoplasm, cytosol
Pathways: Biological oxidation... |
Does Knockout of 4921504E06Rik in breast epithelium causally result in cell cycle progression? | 0 | 1,468 | Knockout | 4921504E06Rik | cell cycle progression | breast epithelium | Gene: 4921504E06Rik (RIKEN cDNA 4921504E06 gene)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q8CET2
Entrez ID: 70909 |
Does Knockout of Cypt2 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 578 | Knockout | Cypt2 | cell proliferation | Embryonic Stem Cell Line | Gene: Cypt2 (cysteine-rich perinuclear theca 2)
Type: protein-coding
Summary: cysteine-rich perinuclear theca 2
Gene Ontology:
Pathways:
UniProt: Q8CH23, Q6P924, A0A9L6KE70
Entrez ID: 245566 |
Does Knockout of Otulin in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 1,273 | Knockout | Otulin | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Otulin (OTU deubiquitinase with linear linkage specificity)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Wnt signaling pathway, angiogenesis, immune system process, innate immune response, negative regulation of NF-kappaB transcription factor activity, negative r... |
Does Knockout of Mrps16 in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation? | 1 | 2,474 | Knockout | Mrps16 | protein/peptide accumulation | Embryonic Fibroblast Cell Line | Gene: Mrps16 (mitochondrial ribosomal protein S16)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: cytosol, mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondri... |
Does Knockout of Triml2 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,679 | Knockout | Triml2 | protein/peptide distribution | myoblast cell line | Gene: Triml2 (tripartite motif family-like 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: innate immune response, response to retinoic acid; MF: identical protein binding, ubiquitin protein ligase activity
Pathways:
UniProt: A0A1B0GSQ3, E9PW10
... |
Does Knockout of Nkain2 in Microglial Cell Line causally result in response to virus? | 0 | 2,429 | Knockout | Nkain2 | response to virus | Microglial Cell Line | Gene: Nkain2 (Na+/K+ transporting ATPase interacting 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: membrane, plasma membrane
Pathways:
UniProt: Q4PNJ2
Entrez ID: 432450 |
Does Knockout of Atic in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,288 | Knockout | Atic | cell proliferation | Mouse kidney carcinoma cell | Gene: Atic (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase)
Type: protein-coding
Summary: Enables IMP cyclohydrolase activity and phosphoribosylaminoimidazolecarboxamide formyltransferase activity. Involved in purine ribonucleoside monophosphate biosynthetic process. ... |
Does Knockout of Ppm1d in Acute Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 684 | Knockout | Ppm1d | cell proliferation | Acute Myeloid Leukemia Cell Line | Gene: Ppm1d (protein phosphatase 1D magnesium-dependent, delta isoform)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, signal transduction by p53 class mediator, DNA methylation-dependent constitutive heterochromatin formation, G2/M transition of mit... |
Does Knockout of Rab3gap2 in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 2,477 | Knockout | Rab3gap2 | cell proliferation | Embryonic Stem Cell Line | Gene: Rab3gap2 (RAB3 GTPase activating protein subunit 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: establishment of protein localization to endoplasmic reticulum membrane, macroautophagy, positive regulation of autophagosome assembly, positive regulation of endopla... |
Does Knockout of Cfap53 in Regulatory T cell causally result in protein/peptide accumulation? | 0 | 1,482 | Knockout | Cfap53 | protein/peptide accumulation | Regulatory T cell | Gene: Cfap53 (cilia and flagella associated protein 53)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell differentiation, cell projection organization, cerebrospinal fluid circulation, cilium assembly, cilium movement, determination of left/right symmetry, epithelial ... |
Does Knockout of Ankrd37 in Melanoma Cell Line causally result in cell proliferation? | 0 | 1,270 | Knockout | Ankrd37 | cell proliferation | Melanoma Cell Line | Gene: Ankrd37 (ankyrin repeat domain 37)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: cytoplasm, cytosol, male germ cell nucleus, mitochondrion, nucleoplasm, nucleus
Pathways:
UniProt: Q569N2
Entrez ID: 654824 |
Does Knockout of Ndufa2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 81 | Knockout | Ndufa2 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Ndufa2 (NADH:ubiquinone oxidoreductase subunit A2)
Type: protein-coding
Summary: This gene encodes a subunit of the NADH-ubiquinone oxidoreductase (complex I) enzyme, which is a large, multimeric protein. It is the first enzyme complex in the mitochondrial electron transport chain and catalyzes th... |
Does Knockout of Tmem35a in macrophage causally result in phagocytosis? | 0 | 1,888 | Knockout | Tmem35a | phagocytosis | macrophage | Gene: Tmem35a (transmembrane protein 35A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chaperone-mediated protein complex assembly, positive regulation of protein localization to cell surface; MF: acetylcholine receptor regulator activity, protein binding; CC: cytoplas... |
Does Knockout of Trub2 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,440 | Knockout | Trub2 | protein/peptide accumulation | Embryonic Cell Line | Gene: Trub2 (TruB pseudouridine (psi) synthase family member 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA modification, RNA processing, mRNA processing, mRNA pseudouridine synthesis, positive regulation of mitochondrial translation, pseudouridine synthesis, tRNA... |
Does Knockout of Tgfb2 in Regulatory T cell causally result in protein/peptide accumulation? | 0 | 1,482 | Knockout | Tgfb2 | protein/peptide accumulation | Regulatory T cell | Gene: Tgfb2 (transforming growth factor, beta 2)
Type: protein-coding
Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transc... |
Does Knockout of Fam110a in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,684 | Knockout | Fam110a | protein/peptide distribution | myoblast cell line | Gene: Fam110a (family with sequence similarity 110, member A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, mitotic spindle organization; CC: cell cortex, cellular_component, centrosome, cytoplasm, cytoskeleton, cytosol, nucleus, spindle microtubule,... |
Does Knockout of Ykt6 in Embryonic Cell Line causally result in protein/peptide accumulation? | 1 | 1,440 | Knockout | Ykt6 | protein/peptide accumulation | Embryonic Cell Line | Gene: Ykt6 (YKT6 v-SNARE homolog (S. cerevisiae))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: endoplasmic reticulum to Golgi vesicle-mediated transport, membrane fusion, protein transport, retrograde transport, endosome to Golgi, vesicle docking involved in exocytosis... |
Does Knockout of Elovl1 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,681 | Knockout | Elovl1 | protein/peptide distribution | myoblast cell line | Gene: Elovl1 (ELOVL fatty acid elongase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ceramide biosynthetic process, establishment of skin barrier, fatty acid biosynthetic process, fatty acid elongation, monounsaturated fatty acid, fatty acid elongation, polyunsatura... |
Does Knockout of Pcsk1 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,679 | Knockout | Pcsk1 | protein/peptide distribution | myoblast cell line | Gene: Pcsk1 (proprotein convertase subtilisin/kexin type 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: insulin processing, peptide biosynthetic process, peptide hormone processing, positive regulation of protein secretion, protein autoprocessing, protein processing, ... |
Does Knockout of Rph3al in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 81 | Knockout | Rph3al | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Rph3al (rabphilin 3A-like (without C2 domains))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: calcium-dependent activation of synaptic vesicle fusion, establishment of localization in cell, exocytosis, glucose homeostasis, intracellular protein transport, negative... |
Does Knockout of Rbm48 in Melanoma Cell Line causally result in cell proliferation? | 1 | 2,492 | Knockout | Rbm48 | cell proliferation | Melanoma Cell Line | Gene: Rbm48 (RNA binding motif protein 48)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, biological_process, mRNA processing; MF: RNA binding, molecular_function, nucleic acid binding; CC: nucleoplasm, spliceosomal complex
Pathways:
UniP... |
Does Knockout of Stard6 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,264 | Knockout | Stard6 | cell proliferation | Colonic Cancer Cell Line | Gene: Stard6 (StAR related lipid transfer domain containing 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: biological_process, lipid transport; MF: cholesterol binding, lipid binding
Pathways: Metabolism, Metabolism of lipids, Metabolism of steroid hormones, ... |
Does Knockout of Polr3gl in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 578 | Knockout | Polr3gl | cell proliferation | Embryonic Stem Cell Line | Gene: Polr3gl (polymerase (RNA) III (DNA directed) polypeptide G like)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: transcription by RNA polymerase III; CC: RNA polymerase III complex, nucleus
Pathways: Cytosolic DNA-sensing pathway - Mus musculus (mouse), Gen... |
Does Knockout of Lsm5 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 1 | 2,307 | Knockout | Lsm5 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: Lsm5 (LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, mRNA catabolic process, mRNA processing, mRNA splicing, via spliceosome, response to bacterium; MF: RNA binding, protein binding, ... |
Does Knockout of Thoc2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 1 | 161 | Knockout | Thoc2 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Thoc2 (THO complex 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA splicing, blastocyst development, cell morphogenesis, generation of neurons, mRNA export from nucleus, mRNA processing, mRNA transport, negative regulation of neuron projection development, ne... |
Does Knockout of Ugt8a in Embryonic Fibroblast Cell Line causally result in autophagy? | 1 | 1,044 | Knockout | Ugt8a | autophagy | Embryonic Fibroblast Cell Line | Gene: Ugt8a (UDP galactosyltransferase 8A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoskeleton organization, galactosylceramide biosynthetic process, glycolipid biosynthetic process, lipid metabolic process, myelination, neuron projection morphogenesis, paranodal... |
Does Knockout of Eif3m in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 81 | Knockout | Eif3m | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Eif3m (eukaryotic translation initiation factor 3, subunit M)
Type: protein-coding
Summary: Enables translation initiation factor binding activity. Acts upstream of or within translation. Part of eukaryotic translation initiation factor 3 complex, eIF3m. Is expressed in several structures, includi... |
Does Knockout of Msl1 in Melanoma Cell Line causally result in cell proliferation? | 1 | 1,270 | Knockout | Msl1 | cell proliferation | Melanoma Cell Line | Gene: Msl1 (male specific lethal 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin organization, chromatin remodeling, positive regulation of DNA-templated transcription; MF: protein binding, protein-macromolecule adaptor activity; CC: MSL complex, nuclear spec... |
Does Knockout of Prmt7 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 82 | Knockout | Prmt7 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Prmt7 (protein arginine N-methyltransferase 7)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell differentiation, chromatin organization, chromatin remodeling, genomic imprinting, methylation, regulation of DNA-templated transcription, spliceosomal snRNP assembly... |
Does Knockout of Twf1 in breast epithelium causally result in cell cycle progression? | 0 | 1,470 | Knockout | Twf1 | cell cycle progression | breast epithelium | Gene: Twf1 (twinfilin actin binding protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: actin filament depolymerization, barbed-end actin filament capping, negative regulation of actin filament polymerization, positive regulation of cardiac muscle hypertrophy, posi... |
Does Knockout of Rcan1 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,287 | Knockout | Rcan1 | cell proliferation | Mouse kidney carcinoma cell | Gene: Rcan1 (regulator of calcineurin 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: calcineurin-NFAT signaling cascade, calcium-mediated signaling, locomotion involved in locomotory behavior, negative regulation of calcineurin-NFAT signaling cascade, negative regulat... |
Does Knockout of Rps15 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 684 | Knockout | Rps15 | cell proliferation | Acute Myeloid Leukemia Cell Line | Gene: Rps15 (ribosomal protein S15)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cytoplasmic translation, liver regeneration, positive regulation of signal transduction by p53 class mediator, rRNA processing, ribosomal small subunit assembly, ribosomal small subunit bi... |
Does Knockout of Rpl32 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 1,265 | Knockout | Rpl32 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Rpl32 (ribosomal protein L32)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to dexamethasone stimulus, cytoplasmic translation, liver regeneration, translation, translation at postsynapse, translation at presynapse; MF: structural constituent of ... |
Does Knockout of Uimc1 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 578 | Knockout | Uimc1 | cell proliferation | Embryonic Stem Cell Line | Gene: Uimc1 (ubiquitin interaction motif containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, chromatin organization, double-strand break repair, mitotic G2 DNA damage checkpoint signalin... |
Does Knockout of Capn13 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 578 | Knockout | Capn13 | cell proliferation | Embryonic Stem Cell Line | Gene: Capn13 (calpain 13)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: proteolysis; MF: calcium ion binding, calcium-dependent cysteine-type endopeptidase activity, cysteine-type peptidase activity, hydrolase activity, peptidase activity
Pathways: Degradation ... |
Does Knockout of Ropn1 in Microglial Cell Line causally result in response to virus? | 0 | 2,429 | Knockout | Ropn1 | response to virus | Microglial Cell Line | Gene: Ropn1 (ropporin, rhophilin associated protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cilium organization, flagellated sperm motility, protein localization to cilium, sperm capacitation; MF: identical protein binding, protein binding, protein heterodimeri... |
Does Knockout of Ubxn7 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,679 | Knockout | Ubxn7 | protein/peptide distribution | myoblast cell line | Gene: Ubxn7 (UBX domain protein 7)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: RNA polymerase II-specific DNA-binding transcription factor binding, ubiquitin binding, ubiquitin protein ligase binding; CC: VCP-NPL4-UFD1 AAA ATPase complex, nucleoplasm, nucleus
... |
Does Knockout of Exoc8 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 1 | 1,265 | Knockout | Exoc8 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Exoc8 (exocyst complex component 8)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: Golgi to plasma membrane transport, endosome organization, exocytosis, extracellular matrix disassembly, intracellular protein localization, membrane fission, mitotic cytokinesis, pr... |
Does Knockout of Xpo5 in Embryonic Stem Cell Line causally result in cell proliferation? | 1 | 2,477 | Knockout | Xpo5 | cell proliferation | Embryonic Stem Cell Line | Gene: Xpo5 (exportin 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RNA export from nucleus, intracellular protein transport, pre-miRNA export from nucleus, protein export from nucleus, protein transport, regulatory ncRNA-mediated gene silencing; MF: RISC complex bind... |
Does Knockout of Ptrh2 in Immortal mouse chromaffin cells causally result in cell viability? | 1 | 2,469 | Knockout | Ptrh2 | cell viability | Immortal mouse chromaffin cells | Gene: Ptrh2 (peptidyl-tRNA hydrolase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of anoikis, negative regulation of gene expression, positive regulation of anoikis; MF: hydrolase activity, peptidyl-tRNA hydrolase activity; CC: cytosol, membrane,... |
Does Knockout of Zbtb45 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,152 | Knockout | Zbtb45 | protein/peptide accumulation | Embryonic Cell Line | Gene: Zbtb45 (zinc finger and BTB domain containing 45)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, nervous system development, regulation of cytokine production, regulation of immune system process; MF: DNA b... |
Does Knockout of Esco2 in Lymphoma Cell Line causally result in response to chemicals? | 1 | 1,536 | Knockout | Esco2 | response to chemicals | Lymphoma Cell Line | Gene: Esco2 (establishment of sister chromatid cohesion N-acetyltransferase 2)
Type: protein-coding
Summary: Enables L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor. Acts upstream of or within several processes, including double-strand break repair; hematopoietic progenitor ce... |
Does Knockout of Ranbp6 in Embryonic Fibroblast Cell Line causally result in response to virus? | 0 | 1,133 | Knockout | Ranbp6 | response to virus | Embryonic Fibroblast Cell Line | Gene: Ranbp6 (RAN binding protein 6)
Type: protein-coding
Summary: Predicted to enable nuclear import signal receptor activity and nuclear localization sequence binding activity. Predicted to be involved in protein import into nucleus. Is active in synapse. Orthologous to human RANBP6 (RAN binding prote... |
Does Knockout of Rabl6 in Embryonic Fibroblast Cell Line causally result in response to virus? | 0 | 1,133 | Knockout | Rabl6 | response to virus | Embryonic Fibroblast Cell Line | Gene: Rabl6 (RAB, member RAS oncogene family-like 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: GTP binding, nucleotide binding; CC: centriolar satellite, centrosome, ciliary basal body, cytoplasm, cytosol, nucleus
Pathways:
UniProt: Q5U3K5
... |
Does Knockout of Dnajc27 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,280 | Knockout | Dnajc27 | cell proliferation | Colonic Adenocarcinoma Cell Line | Gene: Dnajc27 (DnaJ heat shock protein family (Hsp40) member C27)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: intracellular protein transport, positive regulation of ERK1 and ERK2 cascade; MF: GTP binding, GTPase activity, nucleotide binding, protein binding; CC: mito... |
Does Knockout of Rrm1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 1 | 2,307 | Knockout | Rrm1 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: Rrm1 (ribonucleotide reductase M1)
Type: protein-coding
Summary: Enables disordered domain specific binding activity; purine nucleotide binding activity; and ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor. Involved in several processes, including nucleoside phosph... |
Does Knockout of Ccdc92 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,265 | Knockout | Ccdc92 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Ccdc92 (coiled-coil domain containing 92)
Type: protein-coding
Summary: Predicted to enable identical protein binding activity. Predicted to be involved in innate immune response. Predicted to be located in centrosome and nucleoplasm. Predicted to be active in centriole. Is expressed in several st... |
Does Knockout of Cyp2c65 in Melanoma Cell Line causally result in cell proliferation? | 0 | 2,492 | Knockout | Cyp2c65 | cell proliferation | Melanoma Cell Line | Gene: Cyp2c65 (cytochrome P450, family 2, subfamily c, polypeptide 65)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: epoxygenase P450 pathway, estrogen metabolic process, icosanoid biosynthetic process, lipid hydroxylation, organic acid metabolic process, oxidative deme... |
Does Knockout of Keap1 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation? | 1 | 684 | Knockout | Keap1 | cell proliferation | Acute Myeloid Leukemia Cell Line | Gene: Keap1 (kelch-like ECH-associated protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to carbohydrate stimulus, cellular response to interleukin-4, cellular response to oxidative stress, in utero embryonic development, negative regulation of ... |
Does Knockout of Neurl2 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,681 | Knockout | Neurl2 | protein/peptide distribution | myoblast cell line | Gene: Neurl2 (neuralized E3 ubiquitin protein ligase 2)
Type: protein-coding
Summary: Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within sarcomere organization. Located in muscle tendon junction. Part of VCB complex. Is expressed in forebrain; gonad; metanephros; and subma... |
Does Knockout of Trim30a in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,679 | Knockout | Trim30a | protein/peptide distribution | myoblast cell line | Gene: Trim30a (tripartite motif-containing 30A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: activation of innate immune response, autophagy, host-mediated suppression of symbiont invasion, innate immune response, negative regulation of NLRP3 inflammasome complex assem... |
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