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Does Knockout of Ppme1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Ppme1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ppme1 (protein phosphatase methylesterase 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carboxylic ester hydrolase activity, catalytic activity, hydrolase activity, lncRNA binding, protein kinase binding, protein methylesterase activity, protein phosphatase 2A ...
Does Knockout of Rps5 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Rps5
cell proliferation
Melanoma Cell Line
Gene: Rps5 (ribosomal protein S5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, regulation of translational fidelity, ribosomal small subunit biogenesis, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, mRNA b...
Does Knockout of Klk12 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Klk12
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Klk12 (kallikrein related-peptidase 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein maturation, proteolysis; MF: hydrolase activity, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity; CC: extracellular space, secretor...
Does Knockout of Pramel6 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Pramel6
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Pramel6 (PRAME like 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, negative regulation of DNA-templated transcription, negative regulation of apoptotic process, negative regulation of cell differentiation, positive regulation of cell populati...
Does Knockout of Retn in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Retn
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Retn (resistin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fat cell differentiation, negative regulation of feeding behavior, positive regulation of collagen metabolic process, positive regulation of progesterone secretion, positive regulation of smooth muscle ...
Does Knockout of Wdr93 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Wdr93
cell proliferation
Colonic Cancer Cell Line
Gene: Wdr93 (WD repeat domain 93) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q402B2 Entrez ID: 626359
Does Knockout of Crygf in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Crygf
cell proliferation
Colonic Cancer Cell Line
Gene: Crygf (crystallin, gamma F) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to reactive oxygen species, eye development, lens development in camera-type eye, visual perception; MF: structural constituent of eye lens Pathways: Uni...
Does Knockout of Elk1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Elk1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Elk1 (ELK1, member of ETS oncogene family) Type: protein-coding Summary: This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the seru...
Does Knockout of Sptlc2 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Sptlc2
cell proliferation
Colonic Cancer Cell Line
Gene: Sptlc2 (serine palmitoyltransferase, long chain base subunit 2) Type: protein-coding Summary: This gene encodes a long chain base subunit of serine palmitoyltransferase. The enzyme, serine palmitoyltransferase, consists of two different subunits, and is the key enzyme in sphingolipid biosynthesis....
Does Knockout of 2510009E07Rik in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
2510009E07Rik
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: 2510009E07Rik (RIKEN cDNA 2510009E07 gene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: circadian behavior, nervous system development Pathways: UniProt: Q6GQU0 Entrez ID: 72190
Does Knockout of Id2 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Id2
cell proliferation
Embryonic Stem Cell Line
Gene: Id2 (inhibitor of DNA binding 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Peyer's patch development, adipose tissue development, adult locomotory behavior, bundle of His development, cell development, cell differentiation, cell maturation, cell morphogenesis ...
Does Knockout of Acsf3 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Acsf3
protein/peptide distribution
myoblast cell line
Gene: Acsf3 (acyl-CoA synthetase family member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid biosynthetic process, fatty acid metabolic process, lipid metabolic process, malonate catabolic process; MF: ATP binding, CoA-ligase activity, ligase activity, mal...
Does Knockout of Rcan3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Rcan3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rcan3 (regulator of calcineurin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium-mediated signaling; MF: calcium-dependent protein serine/threonine phosphatase regulator activity, nucleic acid binding, phosphatase binding, troponin I binding; CC: cytoplasm...
Does Knockout of Fbxw9 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Fbxw9
cell proliferation
Embryonic Stem Cell Line
Gene: Fbxw9 (F-box and WD-40 domain protein 9) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: Adaptive Immune System, Antigen processing: Ubiquitination & Proteasome degradation, Class I MHC mediated antigen processing & presentation, Immune System, Metab...
Does Knockout of Pth2 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Pth2
protein/peptide distribution
myoblast cell line
Gene: Pth2 (parathyroid hormone 2) Type: protein-coding Summary: This gene encodes the precursor of a peptide hormone that shares sequence similarity with the parathyroid hormone. This gene is expressed in various regions of the brain where it plays a role in the release of pituitary hormones, anxiety a...
Does Knockout of Cd302 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Cd302
protein/peptide distribution
myoblast cell line
Gene: Cd302 (CD302 antigen) Type: protein-coding Summary: No summary available. Gene Ontology: BP: phagocytosis; MF: carbohydrate binding, signaling receptor activity; CC: cell cortex, cell projection, cytoplasm, filopodium, membrane, microvillus Pathways: UniProt: Q9DCG2 ...
Does Knockout of Klhl11 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Klhl11
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Klhl11 (kelch-like 11) Type: protein-coding Summary: Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be acti...
Does Knockout of Gm11544 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Gm11544
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gm11544 (predicted gene 11544) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Nin in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Nin
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Nin (ninein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: centriole-centriole cohesion, centrosome localization, centrosome-templated microtubule nucleation, collateral sprouting, corpus callosum morphogenesis, corticospinal tract morphogenesis, intracellular pro...
Does Knockout of Nrgn in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Nrgn
autophagy
Embryonic Fibroblast Cell Line
Gene: Nrgn (neurogranin) Type: protein-coding Summary: Enables calmodulin binding activity. Predicted to be involved in positive regulation of long-term synaptic potentiation and postsynaptic modulation of chemical synaptic transmission. Predicted to act upstream of or within intracellular signal transd...
Does Knockout of Zbtb7c in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Zbtb7c
protein/peptide distribution
myoblast cell line
Gene: Zbtb7c (zinc finger and BTB domain containing 7C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of cell population proliferation, positive regulation of fat cell differentiation, positive regulation of transcription by RNA polymerase II, regula...
Does Knockout of Pigl in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Pigl
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Pigl (phosphatidylinositol glycan anchor biosynthesis, class L) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GPI anchor biosynthetic process, lipid metabolic process; MF: N-acetylglucosaminylphosphatidylinositol deacetylase activity, hydrolase activity; CC: endop...
Does Knockout of Mrps21 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Mrps21
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mrps21 (mitochondrial ribosomal protein S21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondrion, ribon...
Does Knockout of Sytl3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Sytl3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Sytl3 (synaptotagmin-like 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: exocytosis, intracellular protein transport; MF: calcium-dependent phospholipid binding, neurexin family protein binding, phospholipid binding, protein binding, small GTPase binding, zinc i...
Does Knockout of Pde4dip in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Pde4dip
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Pde4dip (phosphodiesterase 4D interacting protein (myomegalin)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: astral microtubule organization, centrosome cycle, positive regulation of microtubule nucleation, protein-containing complex assembly, regulation of Golgi...
Does Knockout of Krt78 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Krt78
protein/peptide accumulation
Regulatory T cell
Gene: Krt78 (keratin 78) Type: protein-coding Summary: Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Is active in cornified envelope. Orthologous to human KRT78 (keratin 78). [provided by Alliance of Genome ...
Does Knockout of Rhox3e in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Rhox3e
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Rhox3e (reproductive homeobox 3E) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: V9GX94, Q4TU90, V9GXY5, V9GXK5, V9GWU0, V9GXD0, V9GXQ1 Entrez ID: 100135657
Does Knockout of Pdp2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Pdp2
cell proliferation
Mouse kidney carcinoma cell
Gene: Pdp2 (pyruvate dehydrogenase phosphatase catalytic subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity, cation binding, hydrolase activity, metal ion binding, phosphoprotein phosphatase activ...
Does Knockout of Pnma1 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Pnma1
protein/peptide distribution
myoblast cell line
Gene: Pnma1 (paraneoplastic antigen MA1) Type: protein-coding Summary: Predicted to be involved in inflammatory response to antigenic stimulus. Predicted to be located in cytoplasm and nucleolus. Orthologous to human PNMA1 (PNMA family member 1). [provided by Alliance of Genome Resources, Jul 2025] ...
Does Knockout of Trmt1l in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Trmt1l
protein/peptide distribution
myoblast cell line
Gene: Trmt1l (tRNA methyltransferase 1 like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adult behavior, adult locomotory behavior, methylation, tRNA N2-guanine methylation, tRNA processing; MF: RNA binding, metal ion binding, methyltransferase activity, tRNA (guanine...
Does Knockout of Serpina10 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Serpina10
protein/peptide distribution
myoblast cell line
Gene: Serpina10 (serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10) Type: protein-coding Summary: The protein encoded by this gene is a member of the large serpin family of proteins, and is also known as serpin PZ-dependent protease inhibitor (ZPI or PZI)...
Does Knockout of Lsm4 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Lsm4
cell proliferation
Colonic Cancer Cell Line
Gene: Lsm4 (LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated) Type: protein-coding Summary: No summary available. Gene Ontology: BP: P-body assembly, RNA processing, RNA splicing, mRNA processing, mRNA splicing, via spliceosome, nuclear-transcribed mRNA catabolic process, spli...
Does Knockout of Kif21b in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Kif21b
protein/peptide accumulation
Embryonic Cell Line
Gene: Kif21b (kinesin family member 21B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, corpus callosum development, microtubule-based movement, regulation of postsynaptic membrane neurotransmitter receptor levels, retrograde dendritic transport; MF: A...
Does Knockout of Cystm1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Cystm1
cell proliferation
Embryonic Stem Cell Line
Gene: Cystm1 (cysteine-rich transmembrane module containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: Immune System, Innate Immune System, Neutrophil degranulation UniProt: Q8K353 Entrez ID: 66060
Does Knockout of Mrpl20 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Mrpl20
cell proliferation
Mouse kidney carcinoma cell
Gene: Mrpl20 (mitochondrial ribosomal protein L20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: rRNA binding, structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitoch...
Does Knockout of Stxbp3 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Stxbp3
cell viability
Immortal mouse chromaffin cells
Gene: Stxbp3 (syntaxin binding protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, cellular response to type II interferon, exocytosis, insulin secretion, intracellular glucose homeostasis, intracellular protein transport, negative regulation of ...
Does Knockout of Fbxw2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Fbxw2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Fbxw2 (F-box and WD-40 domain protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9QUH1, Q8BS25, Q9CPQ6, Q8CCH8, A2AUF9, A2AUG1 Entrez ID: 30050
Does Knockout of Paxip1 in Lymphoma Cell Line causally result in response to chemicals?
0
1,551
Knockout
Paxip1
response to chemicals
Lymphoma Cell Line
Gene: Paxip1 (PAX interacting (with transcription-activation domain) protein 1) Type: protein-coding Summary: This gene encodes a nuclear-localized protein that contains six BRCT1 (C-terminal of breast cancer susceptibility protein) domains. The encoded protein is involved in the repair of DNA double-st...
Does Knockout of Zfp131 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Zfp131
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Zfp131 (zinc finger protein 131) Type: protein-coding Summary: This gene encodes a member of the BTB/POZ family of transcription factors. This protein has been found to act as a transcriptional activator and may regulate estrogen receptor signaling. Alternative splicing results in multiple transcr...
Does Knockout of Prmt9 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Prmt9
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Prmt9 (protein arginine methyltransferase 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin remodeling, mRNA processing, methylation, regulation of DNA-templated transcription; MF: histone methyltransferase activity, methyltransferase activity, protein-ar...
Does Knockout of Txlnb in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Txlnb
protein/peptide distribution
myoblast cell line
Gene: Txlnb (taxilin beta) Type: protein-coding Summary: No summary available. Gene Ontology: MF: molecular_function, syntaxin binding; CC: cytoplasm Pathways: UniProt: Q8VBT1 Entrez ID: 378431
Does Knockout of Ints6 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ints6
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ints6 (integrator complex subunit 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II transcription initiation surveillance, protein localization to chromatin, snRNA 3'-end processing, snRNA processing, transcription by RNA polymerase II, transcript...
Does Knockout of Pcnx2 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Pcnx2
protein/peptide distribution
myoblast cell line
Gene: Pcnx2 (pecanex homolog 2) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q5DU28 Entrez ID: 270109
Does Knockout of Sapcd2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Sapcd2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sapcd2 (suppressor APC domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, establishment of mitotic spindle orientation, negative regulation of protein localization to cell cortex, positive regulation of cell population proliferation,...
Does Knockout of Cd274 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,271
Knockout
Cd274
cell proliferation
Mouse kidney carcinoma cell
Gene: Cd274 (CD274 antigen) Type: protein-coding Summary: The protein encoded by this gene is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane p...
Does Knockout of Lyrm4 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Lyrm4
protein/peptide distribution
myoblast cell line
Gene: Lyrm4 (LYR motif containing 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: [2Fe-2S] cluster assembly, [4Fe-4S] cluster assembly, iron-sulfur cluster assembly; MF: molecular_function, protein homodimerization activity, structural molecule activity; CC: L-cysteine...
Does Knockout of Rack1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Rack1
cell proliferation
Embryonic Stem Cell Line
Gene: Rack1 (receptor for activated C kinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cellular response to glucose stimulus, cellular response to growth factor stimulus, gastrulation, intracellular protein localization, intracellular signal tr...
Does Knockout of B3gnt2 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
B3gnt2
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: B3gnt2 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2) Type: protein-coding Summary: Predicted to enable N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity. Acts upstream of or within several processes, including axon guidance; cellular response to leukemia inh...
Does Knockout of Ndrg1 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Ndrg1
cell viability
Immortal mouse chromaffin cells
Gene: Ndrg1 (N-myc downstream regulated gene 1) Type: protein-coding Summary: Predicted to enable cadherin binding activity; small GTPase binding activity; and tubulin binding activity. Involved in negative regulation of cell population proliferation and peripheral nervous system myelin maintenance. Act...
Does Knockout of Tfrc in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,287
Knockout
Tfrc
cell proliferation
Mouse kidney carcinoma cell
Gene: Tfrc (transferrin receptor) Type: protein-coding Summary: This gene encodes a cell surface receptor necessary for cellular iron uptake by the process of receptor-mediated endocytosis. This receptor is required for erythropoiesis and neurologic development. Mice that are deficient in this receptor ...
Does Knockout of Ufsp2 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Ufsp2
cell proliferation
Mouse kidney carcinoma cell
Gene: Ufsp2 (UFM1-specific peptidase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of proteolysis involved in protein catabolic process, proteolysis, regulation of intracellular estrogen receptor signaling pathway, regulation of type II interferon...
Does Knockout of Shq1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Shq1
protein/peptide distribution
myoblast cell line
Gene: Shq1 (SHQ1 homolog (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: box H/ACA snoRNP assembly, positive regulation of TORC1 signaling, protein-RNA complex assembly, regulation of androgen receptor signaling pathway; CC: cytoplasm, cytosol, nucleoplas...
Does Knockout of Slc30a6 in Microglial Cell Line causally result in protein/peptide distribution?
1
1,585
Knockout
Slc30a6
protein/peptide distribution
Microglial Cell Line
Gene: Slc30a6 (solute carrier family 30 (zinc transporter), member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to endosome transport, monoatomic cation transport, monoatomic ion transport, regulation of zinc ion transport, transmembrane transport, zinc ion im...
Does Knockout of Scx in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Scx
protein/peptide distribution
myoblast cell line
Gene: Scx (scleraxis scleraxis bHLH transcription factor) Type: protein-coding Summary: This gene encodes a basic helix-loop-helix type transcription factor involved in mesoderm and heart valve formation. The encoded protein is expressed during embryonic development of tendons and ligaments. The gene pr...
Does Knockout of Sorl1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Sorl1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Sorl1 (sortilin-related receptor, LDLR class A repeats-containing) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive thermogenesis, amyloid-beta formation, cell migration, diet induced thermogenesis, endocytosis, endosome to plasma membrane protein transport,...
Does Knockout of Mettl21a in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Mettl21a
protein/peptide distribution
myoblast cell line
Gene: Mettl21a (methyltransferase 21A, HSPA lysine) Type: protein-coding Summary: No summary available. Gene Ontology: BP: methylation, negative regulation of protein folding, protein methylation; MF: ATPase binding, Hsp70 protein binding, heat shock protein binding, methyltransferase activity,...
Does Knockout of Fancl in Lymphoma Cell Line causally result in response to chemicals?
1
1,553
Knockout
Fancl
response to chemicals
Lymphoma Cell Line
Gene: Fancl (Fanconi anemia, complementation group L) Type: protein-coding Summary: This gene encodes the complementation group L subunit of the multimeric Fanconi anemia (FA) nuclear complex composed of proteins encoded by over ten Fanconi anemia complementation (FANC) group genes. The FA complex is ne...
Does Knockout of Lgi4 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Lgi4
cell viability
Immortal mouse chromaffin cells
Gene: Lgi4 (leucine-rich repeat LGI family, member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Schwann cell development, adult locomotory behavior, glial cell development, glial cell proliferation, gliogenesis, myelination, myelination in peripheral nervous system,...
Does Knockout of Vmn1r7 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Vmn1r7
response to chemicals
Pancreatic Cancer Cell Line
Gene: Vmn1r7 (vomeronasal 1 receptor 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromone bi...
Does Knockout of Dimt1 in Lung Cancer Cell Line causally result in tumorigenicity?
0
1,089
Knockout
Dimt1
tumorigenicity
Lung Cancer Cell Line
Gene: Dimt1 (DIM1 rRNA methyltransferase and ribosome maturation factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: methylation, positive regulation of rRNA processing, rRNA methylation, rRNA modification, rRNA processing, ribosomal small subunit biogenesis; MF: 18S ...
Does Knockout of Haus2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Haus2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Haus2 (HAUS augmin-like complex, subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, centrosome cycle, microtubule nucleation, microtubule organizing center organization, spindle assembly; CC: HAUS complex, centrosome, cytoplasm, cytoskeleton, ...
Does Knockout of Havcr1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Havcr1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Havcr1 (hepatitis A virus cellular receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: phagocytosis, engulfment, positive regulation of mast cell activation, response to lipopolysaccharide, response to wounding, symbiont entry into host cell; MF: phosphatidy...
Does Knockout of Abra in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Abra
cell proliferation
Mouse kidney carcinoma cell
Gene: Abra (actin-binding Rho activating protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, positive regulation of DNA-templated transcription, positive regulation of Rho protein signal transduction, positive regulation of transcript...
Does Knockout of Bmpr1b in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Bmpr1b
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Bmpr1b (bone morphogenetic protein receptor, type 1B) Type: protein-coding Summary: This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type I receptor, and forms a complex of two type II and two type I receptors...
Does Knockout of Rnf13 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Rnf13
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Rnf13 (ring finger protein 13) Type: protein-coding Summary: This gene encodes a member of the PA-TM-RING family of proteins that contain a protease associated (PA) domain and a RING finger domain separated by a transmembrane (TM) domain. The encoded protein is an E3 ubiquitin ligase localized to ...
Does Knockout of Alg2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
578
Knockout
Alg2
cell proliferation
Embryonic Stem Cell Line
Gene: Alg2 (ALG2 alpha-1,3/1,6-mannosyltransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: dolichol-linked oligosaccharide biosynthetic process, protein N-linked glycosylation, protein glycosylation; MF: GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferas...
Does Knockout of Rars2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,172
Knockout
Rars2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Rars2 (arginyl-tRNA synthetase 2, mitochondrial) Type: protein-coding Summary: Predicted to enable arginine-tRNA ligase activity. Predicted to be involved in arginyl-tRNA aminoacylation and mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including alimentar...
Does Knockout of Psma2 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Psma2
cell proliferation
Melanoma Cell Line
Gene: Psma2 (proteasome subunit alpha 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis involved in protein catabolic process, response to virus, ubiquitin-dependent protein catabolic process;...
Does Knockout of Vwa3a in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Vwa3a
cell proliferation
Melanoma Cell Line
Gene: Vwa3a (von Willebrand factor A domain containing 3A) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q3UVV9 Entrez ID: 233813
Does Knockout of Rnf8 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Rnf8
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rnf8 (ring finger protein 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, cell division, chromatin organization, double-strand break repair, double-strand break repair via nonhomologous e...
Does Knockout of Rcor2 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Rcor2
cell proliferation
Melanoma Cell Line
Gene: Rcor2 (REST corepressor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: enzyme binding, protein binding, transcription corepressor activity; CC: chromatin, h...
Does Knockout of Pced1b in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Pced1b
response to virus
Microglial Cell Line
Gene: Pced1b (PC-esterase domain containing 1B) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8BGX1 Entrez ID: 239647
Does Knockout of Podxl in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Podxl
response to virus
Embryonic Fibroblast Cell Line
Gene: Podxl (podocalyxin-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell migration, epithelial tube formation, leukocyte migration, negative regulation of cell adhesion, negative regulation of cell-cell adhesion, podocyte development, positive re...
Does Knockout of Sdhb in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Sdhb
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sdhb (succinate dehydrogenase complex, subunit B, iron sulfur (Ip)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, mitochondrial electron transport, succinate to ubiquinone, proton motive force-driven mitochondrial ATP synthesis, respiratory el...
Does Knockout of Mir9-1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Mir9-1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Mir9-1 (microRNA 9-1) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I...
Does Knockout of Ldb3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Ldb3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ldb3 (LIM domain binding 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, heart development, muscle structure development, sarcomere organization; MF: actin binding, cytoskeletal protein binding, enzyme binding, metal ion binding, ...
Does Knockout of Zmpste24 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Zmpste24
cell proliferation
Embryonic Stem Cell Line
Gene: Zmpste24 (zinc metallopeptidase, STE24) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CAAX-box protein processing, CAMKK-AMPK signaling cascade, DNA damage response, DNA repair, adult walking behavior, bone mineralization, calcium ion import into sarcoplasmic reti...
Does Knockout of Spidr in Lymphoma Cell Line causally result in response to chemicals?
1
1,525
Knockout
Spidr
response to chemicals
Lymphoma Cell Line
Gene: Spidr (scaffolding protein involved in DNA repair) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, cellular response to camptothecin, cellular response to hydroxyurea, cellular response to ionizing radiation, doubl...
Does Knockout of Wsb2 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Wsb2
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Wsb2 (WD repeat and SOCS box-containing 2) Type: protein-coding Summary: Predicted to be involved in protein polyubiquitination. Is expressed in several structures, including central nervous system; gonad; lung; stomach; and urinary system. Orthologous to human WSB2 (WD repeat and SOCS box contain...
Does Knockout of Gpc1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Gpc1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Gpc1 (glypican 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Schwann cell differentiation, cell migration, heparan sulfate proteoglycan catabolic process, myelin assembly, negative regulation of fibroblast growth factor receptor signaling pathway, positive regu...
Does Knockout of Mcoln2 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Mcoln2
protein/peptide distribution
myoblast cell line
Gene: Mcoln2 (mucolipin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, calcium ion transmembrane transport, calcium ion transport, calcium-mediated signaling, immune system process, innate immune response, iron ion transmembrane transport, ma...
Does Knockout of Six2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Six2
cell viability
Immortal mouse chromaffin cells
Gene: Six2 (sine oculis-related homeobox 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterior/posterior axis specification, cell fate specification, cell migration, cell population proliferation, chondrocyte differentiation, condensed mesenchymal cell proliferation...
Does Knockout of 4921517D22Rik in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
4921517D22Rik
cell proliferation
Colonic Cancer Cell Line
Gene: 4921517D22Rik (RIKEN cDNA 4921517D22 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A0A286YDE0, Q8CET0 Entrez ID: 70900
Does Knockout of Senp3 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Senp3
protein/peptide distribution
myoblast cell line
Gene: Senp3 (SUMO/sentrin specific peptidase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of double-strand break repair via homologous recombination, protein desumoylation, proteolysis; MF: cysteine-type deubiquitinase activity, cysteine-type pep...
Does Knockout of Tle1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Tle1
protein/peptide distribution
myoblast cell line
Gene: Tle1 (transducin-like enhancer of split 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, negative regulation of DNA-templated transcription, negative regulation of Wnt signaling pathway, negative regulation of anoikis, negative regulation of...
Does Knockout of Cs in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Cs
protein/peptide distribution
Microglial Cell Line
Gene: Cs (citrate synthase) Type: protein-coding Summary: The protein encoded by this gene is a central metabolic pathway enzyme, catalyzing the first step of the tricarboxylic acid cycle in which acetyl coenzyme A and oxaloacetate are converted to citrate and coenzyme A. This enzyme is found in nearly ...
Does Knockout of Dnm2 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Dnm2
cell proliferation
Mouse kidney carcinoma cell
Gene: Dnm2 (dynamin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor internalization, Golgi to plasma membrane transport, actin filament bundle organization, aorta development, autophagy, cellular response to dopamine, centrosome cycle, corona...
Does Knockout of Fndc5 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Fndc5
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Fndc5 (fibronectin type III domain containing 5) Type: protein-coding Summary: This gene encodes a type I transmembrane protein containing fibronectin type III repeat. The encoded transmembrane protein undergoes proteolytic processing to generate a soluble hormone named irisin that is secreted int...
Does Knockout of Mthfd2l in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Mthfd2l
cell proliferation
Colonic Cancer Cell Line
Gene: Mthfd2l (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 10-formyltetrahydrofolate metabolic process, amino acid biosynthetic process, carboxylic acid metabolic process, methionine biosynthetic proces...
Does Knockout of Xrcc6 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Xrcc6
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Xrcc6 (X-ray repair complementing defective repair in Chinese hamster cells 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, V(D)J recombination, activation of innate immune response, cellular hyperosmotic salini...
Does Knockout of Kcnh6 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Kcnh6
protein/peptide accumulation
Embryonic Cell Line
Gene: Kcnh6 (potassium voltage-gated channel, subfamily H (eag-related), member 6) Type: protein-coding Summary: Predicted to enable inward rectifier potassium channel activity. Predicted to be involved in several processes, including potassium ion transmembrane transport; regulation of heart rate by ca...
Does Knockout of Phf23 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Phf23
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Phf23 (PHD finger protein 23) Type: protein-coding Summary: Predicted to enable zinc ion binding activity. Predicted to be involved in negative regulation of autophagosome assembly; negative regulation of autophagosome maturation; and positive regulation of protein ubiquitination. Predicted to be ...
Does Knockout of Tma16 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Tma16
protein/peptide distribution
myoblast cell line
Gene: Tma16 (translation machinery associated 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, ribosomal large subunit biogenesis, ribosome biogenesis; MF: molecular_function, preribosome binding; CC: nucleolus, nucleoplasm, nucleus Pathway...
Does Knockout of Nmb in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Nmb
cell proliferation
Melanoma Cell Line
Gene: Nmb (neuromedin B) Type: protein-coding Summary: This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in satiety, reproduction and thermoregulation...
Does Knockout of Mphosph10 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Mphosph10
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Mphosph10 (M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)) Type: protein-coding Summary: Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in chromosome and nucleolus. Predicted to be part of Mpp10 complex and small-subunit processome. Is exp...
Does Knockout of Pcnt in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Pcnt
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pcnt (pericentrin (kendrin)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain morphogenesis, camera-type eye development, cerebellar cortex morphogenesis, cilium assembly, embryonic brain development, embryonic heart tube development, head development, in utero...
Does Knockout of Zfhx4 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Zfhx4
protein/peptide accumulation
Embryonic Cell Line
Gene: Zfhx4 (zinc finger homeodomain 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA...
Does Knockout of Aif1l in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Aif1l
cell proliferation
Regulatory T cell
Gene: Aif1l (allograft inflammatory factor 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament bundle assembly, ruffle assembly; MF: actin binding, actin filament binding, calcium ion binding, metal ion binding; CC: actin cytoskeleton, actin filament, c...
Does Knockout of Polr2i in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Polr2i
cell viability
Immortal mouse chromaffin cells
Gene: Polr2i (polymerase (RNA) II (DNA directed) polypeptide I) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II, transcription by RNA polymerase II, t...
Does Knockout of Dpysl3 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Dpysl3
autophagy
Embryonic Fibroblast Cell Line
Gene: Dpysl3 (dihydropyrimidinase-like 3) Type: protein-coding Summary: This gene encodes a protein that belongs to the TUC (TOAD-64/Ulip/CRMP) family of proteins. Members of this family are phosphoproteins that function in axonal guidance and neuronal differentiation during development and regeneration...