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Does Knockout of Trmt61a in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Trmt61a
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Trmt61a (tRNA methyltransferase 61A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA processing, mRNA processing, methylation, tRNA methylation, tRNA processing; MF: mRNA (adenine-N1-)-methyltransferase activity, methyltransferase activity, tRNA (adenine(58)-N1)...
Does Knockout of Mir1970 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Mir1970
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Mir1970 (microRNA 1970) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Ddx49 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Ddx49
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ddx49 (DEAD box helicase 49) Type: protein-coding Summary: Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be involved in positive regulation of cell growth; rRNA processing; and regulation of rRNA stability. P...
Does Knockout of Nfil3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Nfil3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nfil3 (nuclear factor, interleukin 3, regulated) Type: protein-coding Summary: The protein encoded by this gene is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters. The encoded protein represses Per1 and Per2 ...
Does Knockout of Rnf114 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Rnf114
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rnf114 (ring finger protein 114) Type: protein-coding Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Predicted to be located in cytosol and plasma membrane. Is expressed in ce...
Does Knockout of Fancc in Lymphoma Cell Line causally result in response to chemicals?
1
1,550
Knockout
Fancc
response to chemicals
Lymphoma Cell Line
Gene: Fancc (Fanconi anemia, complementation group C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, brain morphogenesis, cellular response to oxidative stress, gamete generation, germ cell development, interstrand cross-link repair, myel...
Does Knockout of Leng8 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Leng8
protein/peptide distribution
Microglial Cell Line
Gene: Leng8 (leukocyte receptor cluster (LRC) member 8) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8CBY3 Entrez ID: 232798
Does Knockout of Tmem115 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Tmem115
protein/peptide accumulation
Embryonic Cell Line
Gene: Tmem115 (transmembrane protein 115) Type: protein-coding Summary: No summary available. Gene Ontology: BP: retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; MF: identical protein binding; CC: Golgi apparatus, Golgi cisterna membrane, Golgi transport complex, membrane,...
Does Knockout of Rsl24d1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Rsl24d1
cell proliferation
Embryonic Stem Cell Line
Gene: Rsl24d1 (ribosomal L24 domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ribosomal large subunit biogenesis, ribosome biogenesis; CC: nucleolus, nucleoplasm, nucleus Pathways: Coronavirus disease - COVID-19 - Mus musculus (mouse), Ribosom...
Does Knockout of Lsm6 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Lsm6
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Lsm6 (LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA catabolic process, mRNA processing, mRNA splicing, via spliceosome, maturation of SSU-rRNA, rRNA processing, tRNA processing;...
Does Knockout of Hsf4 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Hsf4
cell proliferation
Mouse kidney carcinoma cell
Gene: Hsf4 (heat shock transcription factor 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lens fiber cell differentiation, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, regulation of DNA-templated trans...
Does Knockout of Ctc1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Ctc1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ctc1 (CTS telomere maintenance complex component 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, bone marrow development, chromosome organization, hematopoietic stem cell proliferation, multicellular organism growth, negative regulation of te...
Does Knockout of Creb1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Creb1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Creb1 (cAMP responsive element binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axonogenesis, cAMP/PKA signal transduction, cell differentiation, cellular response to fatty acid, cellular response to forskolin, cellular response to growth factor st...
Does Knockout of Scarna3b in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Scarna3b
cell proliferation
Melanoma Cell Line
Gene: Scarna3b (small Cajal body-specific RNA 3B) Type: ncRNA Summary: small Cajal body-specific RNA 3B Gene Ontology: BP: RNA processing, biological_process; CC: Cajal body, cellular_component, nucleolus Pathways: UniProt: Entrez ID: 100217447
Does Knockout of Catsperz in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Catsperz
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Catsperz (cation channel sperm associated auxiliary subunit zeta) Type: protein-coding Summary: Involved in flagellated sperm motility; male meiotic nuclear division; and sperm capacitation. Located in sperm principal piece. Part of CatSper complex. Is expressed in alimentary system; genitourinary...
Does Knockout of Rad54l2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Rad54l2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rad54l2 (RAD54 like 2 (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, positive regulation of transcription by RNA polymerase II; MF: ATP binding, ATP hydrolysis activity, ATP-dependent chromatin remodele...
Does Knockout of Ap4b1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Ap4b1
cell proliferation
Mouse kidney carcinoma cell
Gene: Ap4b1 (adaptor-related protein complex AP-4, beta 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular protein transport, protein localization to somatodendritic compartment, protein targeting, protein transport, vesicle-mediated transport; MF: clathrin ...
Does Knockout of Nudt8 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Nudt8
protein/peptide accumulation
Embryonic Cell Line
Gene: Nudt8 (nudix hydrolase 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acetyl-CoA catabolic process, biological_process, butyryl-CoA catabolic process, coenzyme A catabolic process, malonyl-CoA catabolic process, medium-chain fatty-acyl-CoA catabolic process, pro...
Does Knockout of Meaf6 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,286
Knockout
Meaf6
cell proliferation
Mouse kidney carcinoma cell
Gene: Meaf6 (MYST/Esa1-associated factor 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, positive regulation of DNA-templated transcription, positive regulation of double-strand break repair via homologous recombination, re...
Does Knockout of Hdhd3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Hdhd3
cell proliferation
Mouse kidney carcinoma cell
Gene: Hdhd3 (haloacid dehalogenase-like hydrolase domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: CC: mitochondrion, nucleolus, nucleus Pathways: UniProt: Q9CYW4 Entrez ID: 72748
Does Knockout of Fdx1 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Fdx1
cell viability
Immortal mouse chromaffin cells
Gene: Fdx1 (ferredoxin 1) Type: protein-coding Summary: Ferrodoxins are iron-sulfur proteins that facilitate monooxygenase reactions catalyzed by P450 enzymes. The protein encoded by this gene is present in the mitochondrial matrix and transfers electrons from ferredoxin reductase to steroidogenic mitoc...
Does Knockout of Ttc3 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Ttc3
cell proliferation
Melanoma Cell Line
Gene: Ttc3 (tetratricopeptide repeat domain 3) Type: protein-coding Summary: Predicted to enable ubiquitin-protein transferase activity. Involved in negative regulation of axon extension and negative regulation of neuron differentiation. Located in vacuole. Is expressed in several structures, including ...
Does Knockout of Ankrd35 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Ankrd35
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ankrd35 (ankyrin repeat domain 35) Type: protein-coding Summary: No summary available. Gene Ontology: MF: actin binding, molecular_function Pathways: UniProt: D6RGN5, E9Q9D8 Entrez ID: 213121
Does Knockout of Atpaf1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Atpaf1
cell proliferation
Mouse kidney carcinoma cell
Gene: Atpaf1 (ATP synthase mitochondrial F1 complex assembly factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial proton-transporting ATP synthase complex assembly, protein-containing complex assembly; MF: molecular_function, protein-containing complex ...
Does Knockout of Iqsec2 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Iqsec2
cell proliferation
Embryonic Stem Cell Line
Gene: Iqsec2 (IQ motif and Sec7 domain 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, modulation of chemical synaptic transmission, positive regulation of long-term synaptic depression, positive regulation of synapse assembly, positive...
Does Knockout of Nudcd3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Nudcd3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nudcd3 (NudC domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cilium assembly, protein folding, protein localization to pericentriolar material; CC: cytoplasm, cytoplasmic dynein complex Pathways: UniProt: Q8R1N4 Entrez...
Does Knockout of Cadm4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Cadm4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cadm4 (cell adhesion molecule 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules, negative regulation of peptidyl-threonine phosphorylation, negative regulation of peptidyl-tyrosine phosp...
Does Knockout of Gemin7 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Gemin7
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gemin7 (gem nuclear organelle associated protein 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, spliceosomal snRNP assembly; MF: RNA binding, protein binding; CC: Gemini of Cajal bodies, SMN complex, SMN-Sm protein complex, Sm-like...
Does Knockout of 1700018F24Rik in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
1700018F24Rik
autophagy
Embryonic Fibroblast Cell Line
Gene: 1700018F24Rik (RIKEN cDNA 1700018F24 gene) Type: protein-coding Summary: No summary available. Gene Ontology: MF: guanyl-nucleotide exchange factor activity, molecular_function Pathways: UniProt: B2RW27 Entrez ID: 69396
Does Knockout of Sfpq in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Sfpq
cell proliferation
Colonic Cancer Cell Line
Gene: Sfpq (splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, RNA splicing, activation of innate immune response, alternative mRNA splicing, via splice...
Does Knockout of Gm4744 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Gm4744
cell proliferation
Mouse kidney carcinoma cell
Gene: Gm4744 (trypsinogen pseudogene) Type: pseudo Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 194360
Does Knockout of Hmg20a in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Hmg20a
cell proliferation
Mouse kidney carcinoma cell
Gene: Hmg20a (high mobility group 20A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, negative regulation of neuron differentiation, negative regulation of protein sumoylation, negative regulation of transcription by RNA polymerase II, regulation ...
Does Knockout of Xpc in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Xpc
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Xpc (xeroderma pigmentosum, complementation group C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, UV-damage excision repair, mismatch repair, mitotic intra-S DNA damage checkpoint signaling, negative regulation of gluconeogenesis,...
Does Knockout of Pgk1 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Pgk1
response to virus
Embryonic Fibroblast Cell Line
Gene: Pgk1 (phosphoglycerate kinase 1) Type: protein-coding Summary: The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by funct...
Does Knockout of Alx4 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Alx4
protein/peptide distribution
myoblast cell line
Gene: Alx4 (aristaless-like homeobox 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, anterior/posterior pattern specification, digestive tract development, embryonic digit morphogenesis, embryonic forelimb morphogenesis, embryonic hindlimb mor...
Does Knockout of Ffar1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Ffar1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Ffar1 (free fatty acid receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, glucose homeostasis, insulin secretion, ligand-gated ion channel signaling pathway, negative regulation of interleukin-1 beta production,...
Does Knockout of Dr1 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Dr1
response to virus
Microglial Cell Line
Gene: Dr1 (down-regulator of transcription 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of cell cycle, ...
Does Knockout of Cacna1b in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Cacna1b
cell proliferation
Embryonic Stem Cell Line
Gene: Cacna1b (calcium channel, voltage-dependent, N type, alpha 1B subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion import, calcium ion import across plasma membrane, calcium ion transmembrane transport, calcium ion transport, chemical synaptic transm...
Does Knockout of Snap47 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Snap47
response to virus
Embryonic Fibroblast Cell Line
Gene: Snap47 (synaptosomal-associated protein, 47) Type: protein-coding Summary: No summary available. Gene Ontology: BP: exocytic insertion of neurotransmitter receptor to postsynaptic membrane, exocytosis, long-term synaptic potentiation, synaptic vesicle fusion to presynaptic active zone mem...
Does Knockout of Crip2 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Crip2
cell proliferation
Embryonic Stem Cell Line
Gene: Crip2 (cysteine rich protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: hemopoiesis, positive regulation of cell population proliferation; MF: metal ion binding, protein binding Pathways: UniProt: Q9DCT8 Entrez ID: 68337
Does Knockout of Cr2 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Cr2
protein/peptide distribution
myoblast cell line
Gene: Cr2 (complement receptor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation, B cell differentiation, B cell proliferation, T cell mediated immunity, antiviral innate immune response, complement activation, alternative pathway, complement activation...
Does Knockout of Htr1d in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Htr1d
cell proliferation
Mouse kidney carcinoma cell
Gene: Htr1d (5-hydroxytryptamine (serotonin) receptor 1D) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-inhibitin...
Does Knockout of Ap5m1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Ap5m1
protein/peptide distribution
myoblast cell line
Gene: Ap5m1 (adaptor-related protein complex 5, mu 1 subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endosomal transport, protein transport, vesicle-mediated transport; CC: AP-5 adaptor complex, AP-type membrane coat adaptor complex, cytoplasm, cytosol, endosome,...
Does Knockout of Pax4 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Pax4
protein/peptide distribution
myoblast cell line
Gene: Pax4 (paired box 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ morphogenesis, brain development, cell differentiation, circadian rhythm, forebrain development, negative regulation of DNA-templated transcription, negative regulation of apoptotic pro...
Does Knockout of Comt in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Comt
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Comt (catechol-O-methyltransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: artery development, behavioral fear response, catechol-containing compound metabolic process, catecholamine catabolic process, catecholamine metabolic process, cellular response to c...
Does Knockout of Abhd12b in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Abhd12b
cell proliferation
Embryonic Stem Cell Line
Gene: Abhd12b (abhydrolase domain containing 12B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoacylglycerol catabolic process, phosphatidylserine catabolic process; MF: monoacylglycerol lipase activity, phosphatidylcholine lysophospholipase activity Pathwa...
Does Knockout of Naa50 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Naa50
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Naa50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: N-terminal protein amino acid acetylation, chromatin remodeling, establishment of mitotic sister chromatid cohesion, mitotic sister chromatid cohesion, mito...
Does Knockout of Nfkbia in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Nfkbia
response to virus
Embryonic Fibroblast Cell Line
Gene: Nfkbia (nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha) Type: protein-coding Summary: Enables transcription regulator inhibitor activity. Involved in B cell receptor signaling pathway; negative regulation of canonical NF-kappaB signal transduction; and positive...
Does Knockout of Ccndbp1 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Ccndbp1
protein/peptide distribution
myoblast cell line
Gene: Ccndbp1 (cyclin D-type binding-protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, nuclear body, nucleoplasm, nucleus Pathways: UniProt: Q3TVC7 Entrez ID: 17151
Does Knockout of Col14a1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Col14a1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Col14a1 (collagen, type XIV, alpha 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, collagen fibril organization, extracellular matrix organization, homeostasis of number of cells within a tissue, regulation of cell growth involved in cardiac muscle...
Does Knockout of Nod1 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Nod1
response to virus
Embryonic Fibroblast Cell Line
Gene: Nod1 (nucleotide-binding oligomerization domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cellular response to muramyl dipeptide, defense response, defense response to Gram-negative bacterium, defense response to Gram-positive ...
Does Knockout of Krt90 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Krt90
protein/peptide distribution
myoblast cell line
Gene: Krt90 (keratin 90) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intermediate filament organization, keratinization; CC: intermediate filament, keratin filament Pathways: UniProt: E9Q1Z0, Q8BIS2 Entrez ID: 239673
Does Knockout of Ctr9 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Ctr9
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ctr9 (CTR9 homolog, Paf1/RNA polymerase II complex component) Type: protein-coding Summary: Enables SH2 domain binding activity. Involved in several processes, including cell surface receptor signaling pathway; cellular response to lipopolysaccharide; and endodermal cell fate commitment. Acts upst...
Does Knockout of Nup107 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Nup107
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nup107 (nucleoporin 107) Type: protein-coding Summary: Predicted to be a structural constituent of nuclear pore. Predicted to be involved in several processes, including nuclear pore complex assembly; nucleocytoplasmic transport; and post-transcriptional tethering of RNA polymerase II gene DNA at ...
Does Knockout of Ly6g6e in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Ly6g6e
protein/peptide accumulation
Embryonic Cell Line
Gene: Ly6g6e (lymphocyte antigen 6 family member G6E) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acetylcholine receptor signaling pathway, cell surface receptor protein serine/threonine kinase signaling pathway, desensitization of G protein-coupled receptor signaling...
Does Knockout of Il10ra in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Il10ra
cell proliferation
Embryonic Stem Cell Line
Gene: Il10ra (interleukin 10 receptor, alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytokine-mediated signaling pathway, interleukin-10-mediated signaling pathway, intestinal epithelial structure maintenance, negative regulation of autophagy, negative regulation...
Does Knockout of Cnot6 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Cnot6
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cnot6 (CCR4-NOT transcription complex, subunit 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: miRNA-mediated gene silencing by mRNA destabilization, nuclear-transcribed mRNA catabolic process, no-go decay, nuclear-transcribed mRNA poly(A) tail shortening, positi...
Does Knockout of Rragb in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Rragb
cell proliferation
Embryonic Stem Cell Line
Gene: Rragb (Ras-related GTP binding B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to amino acid starvation, cellular response to amino acid stimulus, cellular response to leucine starvation, cellular response to starvation, intracellular protein lo...
Does Knockout of Vps28 in Embryonic Stem Cell Line causally result in cell proliferation?
1
578
Knockout
Vps28
cell proliferation
Embryonic Stem Cell Line
Gene: Vps28 (vacuolar protein sorting 28) Type: protein-coding Summary: This gene encodes a protein which is thought to be a subunit of the ESCRT-I complex (endosomal complexes required for transport), which functions in the transport and sorting of proteins into subcellular vesicles. This complex can a...
Does Knockout of Gas8 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Gas8
protein/peptide distribution
myoblast cell line
Gene: Gas8 (growth arrest specific 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axoneme assembly, brain development, cell motility, cilium movement involved in cell motility, determination of left/right symmetry, epithelial cilium movement involved in extracellular ...
Does Knockout of Cxxc1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Cxxc1
cell proliferation
Embryonic Stem Cell Line
Gene: Cxxc1 (CXXC finger protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, positive regulation of DNA-templated transcription, regulation of DNA-templated transcription; MF: DNA binding, cis-regulatory region sequence-specific DNA binding,...
Does Knockout of Itga10 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Itga10
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Itga10 (integrin, alpha 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell migration, cell-cell adhesion, cell-matrix adhesion, integrin-mediated signaling pathway; MF: collagen binding involved in cell-matrix adhesion, metal ion binding, signal...
Does Knockout of Haus8 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Haus8
cell proliferation
Colonic Cancer Cell Line
Gene: Haus8 (4HAUS augmin-like complex, subunit 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, centrosome cycle, spindle assembly; CC: HAUS complex, centrosome, cytoplasm, cytoskeleton, microtubule, mitotic spindle microtubule, nuclear microtubule, spin...
Does Knockout of Bcas2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Bcas2
protein/peptide accumulation
Embryonic Cell Line
Gene: Bcas2 (BCAS2 pre-mRNA processing factor) Type: protein-coding Summary: Acts upstream of or within several processes, including alternative mRNA splicing, via spliceosome; ovarian follicle development; and spindle assembly. Part of Prp19 complex. Is expressed in several structures, including centra...
Does Knockout of Nup210l in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Nup210l
cell proliferation
Mouse kidney carcinoma cell
Gene: Nup210l (nucleoporin 210-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Sertoli cell development, spermatid development; CC: membrane, nuclear membrane, nuclear pore, nucleoplasm, nucleus Pathways: Amyotrophic lateral sclerosis - Mus musculus (mouse)...
Does Knockout of B3gat2 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
B3gat2
cell proliferation
Melanoma Cell Line
Gene: B3gat2 (beta-1,3-glucuronyltransferase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate biosynthetic process, carbohydrate metabolic process, chondroitin sulfate proteoglycan biosynthetic process, protein glycosylation; MF: galactosylgalactosylxylosyl...
Does Knockout of Tbk1 in Melanoma Cell Line causally result in tumorigenicity?
1
616
Knockout
Tbk1
tumorigenicity
Melanoma Cell Line
Gene: Tbk1 (TANK-binding kinase 1) Type: protein-coding Summary: Enables several functions, including identical protein binding activity; protein phosphatase binding activity; and protein serine/threonine kinase activity. Involved in several processes, including peptidyl-serine phosphorylation; positive...
Does Knockout of Nit1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Nit1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Nit1 (nitrilase 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: [acetyl-CoA carboxylase]-phosphatase activity, deaminated glutathione amidase activity, hydrolase activity, hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; CC...
Does Knockout of Lrrc26 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Lrrc26
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Lrrc26 (leucine rich repeat containing 26) Type: protein-coding Summary: Predicted to enable potassium channel activator activity; transmembrane transporter binding activity; and voltage-gated potassium channel activity. Predicted to be involved in positive regulation of voltage-gated potassium ch...
Does Knockout of Ndufb11 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Ndufb11
protein/peptide distribution
myoblast cell line
Gene: Ndufb11 (NADH:ubiquinone oxidoreductase subunit B11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner membrane, mitochondrion, respiratory chain complex I ...
Does Knockout of Hacd4 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Hacd4
protein/peptide distribution
myoblast cell line
Gene: Hacd4 (3-hydroxyacyl-CoA dehydratase 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid biosynthetic process, fatty acid elongation, fatty acid metabolic process, lipid metabolic process, sphingolipid biosynthetic process, very long-chain fatty acid biosy...
Does Knockout of Gpr31b in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Gpr31b
response to chemicals
Pancreatic Cancer Cell Line
Gene: Gpr31b (G protein-coupled receptor 31, D17Leh66b region) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, negative regulation of inflammatory response, positive regulation of immune response, response to acidic pH, respon...
Does Knockout of Slc35a1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Slc35a1
cell proliferation
Mouse kidney carcinoma cell
Gene: Slc35a1 (solute carrier family 35 (CMP-sialic acid transporter), member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CMP-N-acetylneuraminate biosynthetic process, CMP-N-acetylneuraminate transmembrane transport, N-acetylneuraminate metabolic process, pyrimidin...
Does Knockout of Bean1 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Bean1
cell viability
Immortal mouse chromaffin cells
Gene: Bean1 (brain expressed, associated with Nedd4, 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: Spinocerebellar ataxia - Mus musculus (mouse) UniProt: Q9EQG5 Entrez ID: 65115
Does Knockout of Rfc4 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Rfc4
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Rfc4 (replication factor C (activator 1) 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair, DNA replication, DNA-templated DNA replication, positive regulation of DNA-directed DNA polymerase activity; MF: ATP binding, ATP hydrolysis activity, DNA binding...
Does Knockout of Atf7ip in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Atf7ip
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Atf7ip (activating transcription factor 7 interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA methylation-dependent constitutive heterochromatin formation, negative regulation of DNA-templated transcription, negative regulation of transcription ...
Does Knockout of Tarbp1 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Tarbp1
cell cycle progression
breast epithelium
Gene: Tarbp1 (TAR RNA binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA processing, methylation, tRNA methylation; MF: RNA binding, RNA methyltransferase activity, methyltransferase activity, tRNA (guanine(18)-2'-O)-methyltransferase activity, tRNA (g...
Does Knockout of 1700020A23Rik in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
1700020A23Rik
protein/peptide distribution
myoblast cell line
Gene: 1700020A23Rik (RIKEN cDNA 1700020A23 gene) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q9DA59 Entrez ID: 75656
Does Knockout of Gulo in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Gulo
cell proliferation
Embryonic Stem Cell Line
Gene: Gulo (gulonolactone (L-) oxidase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-ascorbic acid biosynthetic process; MF: D-arabinono-1,4-lactone oxidase activity, FAD binding, L-gulonolactone oxidase activity, flavin adenine dinucleotide binding, oxidoreductase a...
Does Knockout of Spag11a in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Spag11a
protein/peptide distribution
myoblast cell line
Gene: Spag11a (sperm associated antigen 11A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, antifungal humoral response, defense response, defense response to bacterium, negative regulation of interleukin-1 alpha production, negative regul...
Does Knockout of Mtmr3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Mtmr3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Mtmr3 (myotubularin related protein 3) Type: protein-coding Summary: Predicted to enable phosphatase activity and protein phosphatase binding activity. Predicted to be involved in several processes, including cellular response to glucose starvation; phosphatidylinositol metabolic process; and regu...
Does Knockout of Abhd3 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Abhd3
cell proliferation
Colonic Cancer Cell Line
Gene: Abhd3 (abhydrolase domain containing 3) Type: protein-coding Summary: Predicted to enable carboxylic ester hydrolase activity. Involved in phosphatidylcholine metabolic process. Predicted to be located in membrane. Is expressed in several structures, including brain; genitourinary system; liver; o...
Does Knockout of Atg5 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation?
1
2,142
Knockout
Atg5
cell proliferation
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Atg5 (autophagy related 5) Type: protein-coding Summary: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic...
Does Knockout of Trim34b in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Trim34b
protein/peptide accumulation
Regulatory T cell
Gene: Trim34b (tripartite motif-containing 34B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to virus, innate immune response, protein ubiquitination, regulation of gene expression; MF: identical protein binding, metal ion binding, transferase activity...
Does Knockout of Pir in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Pir
protein/peptide accumulation
Mouse cell
Gene: Pir (pirin) Type: protein-coding Summary: Predicted to enable metal ion binding activity; quercetin 2,3-dioxygenase activity; and transcription coregulator activity. Acts upstream of or within myeloid cell differentiation. Predicted to be located in cytosol and nuclear body. Predicted to be active...
Does Knockout of Uts2r in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Uts2r
cell proliferation
Colonic Cancer Cell Line
Gene: Uts2r (urotensin 2 receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, blood circulation, blood vessel diameter maintenance, negative regulation of blood pressure, negative regulation of glomerular filtration, nega...
Does Knockout of Kcnk12 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Kcnk12
cell proliferation
Mouse kidney carcinoma cell
Gene: Kcnk12 (potassium channel, subfamily K, member 12) Type: protein-coding Summary: Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to be active in plasma membrane. O...
Does Knockout of Kcng3 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Kcng3
cell proliferation
Colonic Cancer Cell Line
Gene: Kcng3 (potassium voltage-gated channel, subfamily G, member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: action potential, monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion transmembrane transport, potassium ion transport, protein...
Does Knockout of Mrps33 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Mrps33
protein/peptide distribution
myoblast cell line
Gene: Mrps33 (mitochondrial ribosomal protein S33) Type: protein-coding Summary: No summary available. Gene Ontology: CC: mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondrion, ribonucleoprotein complex, ribosome Pathways: Metabolism of proteins, Mitochondr...
Does Knockout of Plpp5 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Plpp5
cell viability
Immortal mouse chromaffin cells
Gene: Plpp5 (phospholipid phosphatase 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid metabolic process, phospholipid dephosphorylation, phospholipid metabolic process; MF: diacylglycerol diphosphate phosphatase activity, hydrolase activity, phosphatidate phospha...
Does Knockout of Patz1 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Patz1
cell cycle progression
breast epithelium
Gene: Patz1 (POZ (BTB) and AT hook containing zinc finger 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell differentiation, male gonad development, negative regulation of DNA-templated transcription, negative regulation of endothelial cell migration, negative reg...
Does Knockout of Sirt1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Sirt1
protein/peptide accumulation
Embryonic Cell Line
Gene: Sirt1 (sirtuin 1) Type: protein-coding Summary: This gene encodes a member of the sirtuin family of proteins, characterized by their deacetylase activity and proposed role in longevity. The encoded protein regulates gene expression in a wide range of cell and tissue types through its NAD+-dependen...
Does Knockout of Actl6a in Lymphoma Cell Line causally result in response to chemicals?
1
1,558
Knockout
Actl6a
response to chemicals
Lymphoma Cell Line
Gene: Actl6a (actin-like 6A) Type: protein-coding Summary: Enables chromatin binding activity. Involved in several processes, including positive regulation of DNA metabolic process; regulation of embryonic development; and telomere maintenance. Acts upstream of or within blastocyst formation and chromat...
Does Knockout of Slc17a9 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Slc17a9
cell proliferation
Colonic Cancer Cell Line
Gene: Slc17a9 (solute carrier family 17, member 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ADP transport, ATP export, ATP transport, guanine nucleotide transmembrane transport, lysosomal protein catabolic process, purine nucleotide import into lysosome, purine-con...
Does Knockout of Anln in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Anln
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Anln (anillin, actin binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actomyosin contractile ring assembly, cell division, hematopoietic progenitor cell differentiation, mitotic cytokinesis, podocyte cell migration, positive regulation of bleb assemb...
Does Knockout of Rb1cc1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Rb1cc1
autophagy
Embryonic Fibroblast Cell Line
Gene: Rb1cc1 (RB1-inducible coiled-coil 1) Type: protein-coding Summary: Enables protein kinase binding activity. Involved in autophagosome assembly; negative regulation of cell population proliferation; and positive regulation of autophagy. Acts upstream of or within several processes, including defens...
Does Knockout of Pitrm1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Pitrm1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pitrm1 (pitrilysin metallepetidase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein processing, proteolysis; MF: hydrolase activity, metal ion binding, metalloendopeptidase activity, metallopeptidase activity, peptidase activity, zinc ion binding; CC: mito...
Does Knockout of Hivep2 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Hivep2
protein/peptide distribution
myoblast cell line
Gene: Hivep2 (human immunodeficiency virus type I enhancer binding protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II, signal t...
Does Knockout of Omt2b in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Omt2b
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Omt2b (oocyte maturation, beta) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytosol, membrane Pathways: UniProt: A0A087WRQ7, D3YX29, A0A087WQL0 Entrez ID: 382088
Does Knockout of Glo1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Glo1
protein/peptide distribution
myoblast cell line
Gene: Glo1 (glyoxalase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glutathione metabolic process, methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione, methylglyoxal metabolic process, negative regulation of apoptotic process, osteoclast different...