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Does Knockout of Nell2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Nell2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nell2 (NEL-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: commissural neuron axon guidance, development of secondary female sexual characteristics, fertilization, neurogenesis, neuron cellular homeostasis, positive regulation of hormone secretion, regulatio...
Does Knockout of Utp15 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Utp15
cell proliferation
Melanoma Cell Line
Gene: Utp15 (UTP15 small subunit processome component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of rRNA processing, positive regulation of transcription by RNA polymerase I, rRNA processing, ribosomal small subunit biogenesis, ribosome biogenesi...
Does Knockout of Actr2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Actr2
protein/peptide accumulation
Embryonic Cell Line
Gene: Actr2 (actin related protein 2) Type: protein-coding Summary: Predicted to enable cytoskeletal protein binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to contribute to actin filament binding activity. Acts upstream of or within several processes, including cel...
Does Knockout of Trpm7 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Trpm7
cell proliferation
Embryonic Stem Cell Line
Gene: Trpm7 (transient receptor potential cation channel, subfamily M, member 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actomyosin structure organization, calcium ion transmembrane transport, calcium ion transport, calcium-dependent cell-matrix adhesion, intracel...
Does Knockout of Rhbdf1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Rhbdf1
protein/peptide accumulation
Embryonic Cell Line
Gene: Rhbdf1 (rhomboid 5 homolog 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell migration, cell population proliferation, negative regulation of protein secretion, regulation of epidermal growth factor receptor signaling pathway, regulation of proteasomal protein...
Does Knockout of Hr in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Hr
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Hr (Hr, lysine demethylase and nuclear receptor corepressor) Type: protein-coding Summary: This gene encodes a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid recep...
Does Knockout of Erp44 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Erp44
cell proliferation
Colonic Cancer Cell Line
Gene: Erp44 (endoplasmic reticulum protein 44) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glycoprotein metabolic process, protein folding, response to endoplasmic reticulum stress, response to unfolded protein; MF: protein binding, protein disulfide isomerase activit...
Does Knockout of Syap1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Syap1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Syap1 (synapse associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: TORC2 signaling, cell differentiation, cellular response to epidermal growth factor stimulus, cellular response to insulin stimulus, cellular response to insulin-like growth factor ...
Does Knockout of Naa50 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Naa50
cell proliferation
Embryonic Stem Cell Line
Gene: Naa50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: N-terminal protein amino acid acetylation, chromatin remodeling, establishment of mitotic sister chromatid cohesion, mitotic sister chromatid cohesion, mito...
Does Knockout of Cox8a in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Cox8a
protein/peptide distribution
myoblast cell line
Gene: Cox8a (cytochrome c oxidase subunit 8A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial electron transport, cytochrome c to oxygen, oxidative phosphorylation; CC: membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrion, respirator...
Does Knockout of Ucn in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Ucn
response to chemicals
Pancreatic Cancer Cell Line
Gene: Ucn (urocortin) Type: protein-coding Summary: This gene encodes a member of the corticotropin-releasing hormone peptide family that participates in coordinating autonomic, endocrine, and behavioral responses to stress. The encoded preproprotein undergoes proteolytic processing to generate a mature...
Does Knockout of Chchd2 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Chchd2
cell cycle progression
breast epithelium
Gene: Chchd2 (coiled-coil-helix-coiled-coil-helix domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to oxidative stress, mitochondrion organization, positive regulation of mitochondrial ATP synthesis coupled electron transport, positiv...
Does Knockout of Vsig1 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Vsig1
protein/peptide distribution
myoblast cell line
Gene: Vsig1 (V-set and immunoglobulin domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: epithelial cell morphogenesis, maintenance of gastrointestinal epithelium; CC: basolateral plasma membrane, membrane, plasma membrane Pathways: Un...
Does Knockout of Gps2 in Malignant Peripheral Nerve Sheath Tumor (MPNST) cancer cell causally result in cell proliferation?
1
2,182
Knockout
Gps2
cell proliferation
Malignant Peripheral Nerve Sheath Tumor (MPNST) cancer cell
Gene: Gps2 (G protein pathway suppressor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, negative regulation of B cell receptor signaling pathway, negative regulation of JNK cascade, negative regulation of fat cell differentiation, negative regu...
Does Knockout of Pramel6 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Pramel6
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pramel6 (PRAME like 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, negative regulation of DNA-templated transcription, negative regulation of apoptotic process, negative regulation of cell differentiation, positive regulation of cell populati...
Does Knockout of Mtnr1b in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Mtnr1b
protein/peptide distribution
myoblast cell line
Gene: Mtnr1b (melatonin receptor 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, circadian rhythm, glucose homeostasis, negative regulation of cGMP-mediated signaling, negative regulation of cytosolic calcium ion concentra...
Does Knockout of Acly in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,286
Knockout
Acly
cell proliferation
Mouse kidney carcinoma cell
Gene: Acly (ATP citrate lyase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acetyl-CoA biosynthetic process, acetyl-CoA metabolic process, acyl-CoA biosynthetic process, citrate metabolic process, fatty acid biosynthetic process, lipid biosynthetic process, lipid metab...
Does Knockout of 4930407I10Rik in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
4930407I10Rik
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: 4930407I10Rik (RIKEN cDNA 4930407I10 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: D3Z5T8 Entrez ID: 328573
Does Knockout of Ctag2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Ctag2
protein/peptide accumulation
Embryonic Cell Line
Gene: Ctag2 (cancer/testis antigen 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: tRNA processing, tRNA threonylcarbamoyladenosine metabolic process; CC: EKC/KEOPS complex, cytoplasm, nucleus Pathways: UniProt: Q9D9S4 Entrez ID: 70062
Does Knockout of Cxcr4 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Cxcr4
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cxcr4 (C-X-C motif chemokine receptor 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CXCL12-activated CXCR4 signaling pathway, G protein-coupled receptor signaling pathway, T cell proliferation, adenylate cyclase-inhibiting G protein-coupled receptor signaling p...
Does Knockout of Mxd3 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Mxd3
cell proliferation
Embryonic Stem Cell Line
Gene: Mxd3 (Max dimerization protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-bi...
Does Knockout of Mtg1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Mtg1
cell proliferation
Melanoma Cell Line
Gene: Mtg1 (mitochondrial ribosome-associated GTPase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial large ribosomal subunit assembly, regulation of mitochondrial translation, regulation of respiratory system process, regulation of translation; MF: GTP bi...
Does Knockout of Ttk in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ttk
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ttk (Ttk protein kinase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromosome segregation, female meiosis chromosome segregation, meiotic spindle assembly checkpoint signaling, mitotic spindle assembly checkpoint signaling, nuclear chromosome segregation, nucl...
Does Knockout of Kank1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Kank1
protein/peptide accumulation
Regulatory T cell
Gene: Kank1 (KN motif and ankyrin repeat domains 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, cell population proliferation, cortical microtubule organization, negative regulation of Rho protein signal transduction, negative regulati...
Does Knockout of Il22ra1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Il22ra1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Il22ra1 (interleukin 22 receptor, alpha 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytokine-mediated signaling pathway, defense response to Gram-negative bacterium, interleukin-22-mediated signaling pathway, negative regulation of cytokine production involve...
Does Knockout of Gm15013 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Gm15013
cell proliferation
Mouse kidney carcinoma cell
Gene: Gm15013 (ribosomal protein S4, X-linked pseudogene) Type: pseudo Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 100417274
Does Knockout of Ago2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ago2
cell proliferation
Embryonic Stem Cell Line
Gene: Ago2 (argonaute RISC catalytic subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: P-body assembly, RISC complex assembly, RNA stabilization, cell differentiation, gene expression, miRNA metabolic process, miRNA processing, miRNA-mediated gene silencing by in...
Does Knockout of Tff3 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Tff3
cell proliferation
Melanoma Cell Line
Gene: Tff3 (trefoil factor 3, intestinal) Type: protein-coding Summary: Predicted to enable identical protein binding activity. Involved in regulation of glucose metabolic process. Located in secretory granule. Is expressed in several structures, including alimentary system; integumental system; metanep...
Does Knockout of Abcb1b in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Abcb1b
protein/peptide distribution
myoblast cell line
Gene: Abcb1b (ATP-binding cassette, sub-family B member 1B) Type: protein-coding Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. A...
Does Knockout of Las1l in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Las1l
protein/peptide distribution
myoblast cell line
Gene: Las1l (LAS1-like (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of 5.8S rRNA, maturation of LSU-rRNA, rRNA processing; MF: endonuclease activity, hydrolase activity; CC: Las1 complex, MLL1 complex, cytoplasm, nucleolus, nucleoplasm, nucl...
Does Knockout of Dad1 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Dad1
cell proliferation
Melanoma Cell Line
Gene: Dad1 (defender against cell death 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, blastocyst development, negative regulation of apoptotic process, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein glycosyla...
Does Knockout of Ugdh in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Ugdh
cell proliferation
Colonic Cancer Cell Line
Gene: Ugdh (UDP-glucose dehydrogenase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: UDP-glucuronate biosynthetic process, chondroitin sulfate proteoglycan biosynthetic process, gastrulation with mouth forming second, glycosaminoglycan biosynthetic process, heparan sulf...
Does Knockout of Fan1 in Lymphoma Cell Line causally result in response to chemicals?
1
1,545
Knockout
Fan1
response to chemicals
Lymphoma Cell Line
Gene: Fan1 (FANCD2/FANCI-associated nuclease 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, double-strand break repair via homologous recombination, interstrand cross-link repair, nucleotide-excision repair; MF: 5'-3' exonuclease activ...
Does Knockout of Rrm2b in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Rrm2b
cell cycle progression
breast epithelium
Gene: Rrm2b (ribonucleotide reductase M2 B (TP53 inducible)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 2'-deoxyribonucleotide biosynthetic process, DNA damage response, DNA repair, DNA synthesis involved in DNA repair, deoxyribonucleoside triphosphate metabolic proc...
Does Knockout of Pole in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Pole
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Pole (polymerase (DNA directed), epsilon) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA biosynthetic process, DNA damage response, DNA metabolic process, DNA repair, DNA replication, DNA replication proofreading, DNA synthesis involved in DNA repair, DNA-templ...
Does Knockout of Gabpb1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Gabpb1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gabpb1 (GA repeat binding protein, beta 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrion organization, positive regulation of transcription by RNA polymerase II; MF: protein binding, transcription cis-regulatory region binding; CC: cytoplasmic ribonu...
Does Knockout of Dnaja1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Dnaja1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1) Type: protein-coding Summary: The protein encoded by this gene is a member of the DnaJ family, whose members act as cochaperones of heat shock protein 70. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregatio...
Does Knockout of Ociad1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Ociad1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ociad1 (OCIA domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: endosome, mitochondrion Pathways: UniProt: Q9CRD0 Entrez ID: 68095
Does Knockout of 4930590J08Rik in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
4930590J08Rik
response to virus
Embryonic Fibroblast Cell Line
Gene: 4930590J08Rik (RIKEN cDNA 4930590J08 gene) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, membrane Pathways: UniProt: Q8CDN1 Entrez ID: 381798
Does Knockout of Brca2 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Brca2
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Brca2 (breast cancer 2, early onset) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA damage response, signal transduction by p53 class mediator, DNA recombination, DNA repair, brain development, cell population proliferation, cellular respon...
Does Knockout of Zfp146 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Zfp146
protein/peptide accumulation
Regulatory T cell
Gene: Zfp146 (zinc finger protein 146) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II transcription regulatory region sequence-specific DNA binding, metal ion binding, z...
Does Knockout of Nup43 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Nup43
protein/peptide distribution
myoblast cell line
Gene: Nup43 (nucleoporin 43) Type: protein-coding Summary: Predicted to be involved in nucleocytoplasmic transport. Predicted to be located in cytosol; nuclear envelope; and nuclear speck. Predicted to be part of nuclear pore outer ring. Predicted to colocalize with kinetochore. Is expressed in several ...
Does Knockout of Orc1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Orc1
cell proliferation
Melanoma Cell Line
Gene: Orc1 (origin recognition complex, subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, DNA replication initiation, mitotic DNA replication checkpoint signaling, positive regulation of G0 to G1 transition, positive regulation of smooth muscle c...
Does Knockout of Casz1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Casz1
protein/peptide distribution
myoblast cell line
Gene: Casz1 (castor zinc finger 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of amacrine cell differentiation, negative regulation of glial cell differentiation, negative regulation of neuron differentiation, negative regulation of retinal cone c...
Does Knockout of Dmrtc1a in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Dmrtc1a
protein/peptide accumulation
Mouse cell
Gene: Dmrtc1a (DMRT-like family C1a) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding Pathways: UniProt: Q9D9R7 ...
Does Knockout of Dnajb6 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Dnajb6
protein/peptide distribution
myoblast cell line
Gene: Dnajb6 (DnaJ heat shock protein family (Hsp40) member B6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, chorio-allantoic fusion, chorion development, extracellular matrix organization, intermediate filament organization, negative r...
Does Knockout of Nyap2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Nyap2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Nyap2 (neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: neuron projection morphogenesis, phosphatidylinositol 3-kinase/protein kinase B signal transduction Pathways: UniProt: A0A0...
Does Knockout of Scgb2b24 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Scgb2b24
protein/peptide distribution
myoblast cell line
Gene: Scgb2b24 (secretoglobin, family 2B, member 24) Type: protein-coding Summary: Predicted to be located in extracellular space. [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: CC: cellular_component, extracellular region, extracellular space Pathways: U...
Does Knockout of Lyz1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Lyz1
cell proliferation
Mouse kidney carcinoma cell
Gene: Lyz1 (lysozyme 1) Type: protein-coding Summary: Predicted to enable identical protein binding activity and lysozyme activity. Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Predicted to be located in several cellular components, including G...
Does Knockout of Il6ra in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Il6ra
protein/peptide accumulation
Embryonic Cell Line
Gene: Il6ra (interleukin 6 receptor, alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T-helper 17 cell lineage commitment, cell surface receptor signaling pathway via JAK-STAT, cell surface receptor signaling pathway via STAT, ciliary neurotrophic factor-mediated si...
Does Knockout of Klk1b24 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Klk1b24
protein/peptide distribution
myoblast cell line
Gene: Klk1b24 (kallikrein 1-related peptidase b24) Type: protein-coding Summary: This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasti...
Does Knockout of Top1 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Top1
cell viability
Immortal mouse chromaffin cells
Gene: Top1 (topoisomerase (DNA) I) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, DNA topological change, animal organ regeneration, cellular response to luteinizing hormone stimulus, chromatin remodeling, chromosome segregation, circadian regulation of ...
Does Knockout of Grk4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Grk4
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Grk4 (G protein-coupled receptor kinase 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor internalization, desensitization of G protein-coupled receptor signaling pathway, receptor internalization, regulation of signal transduction, signa...
Does Knockout of Cltc in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Cltc
protein/peptide distribution
myoblast cell line
Gene: Cltc (clathrin heavy chain) Type: protein-coding Summary: Enables protein kinase binding activity. Predicted to be involved in several processes, including amyloid-beta clearance by transcytosis; endocytosis; and negative regulation of hyaluronan biosynthetic process. Predicted to act upstream of ...
Does Knockout of Aqp11 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Aqp11
cell proliferation
Regulatory T cell
Gene: Aqp11 (aquaporin 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endosomal lumen acidification, glycerol transmembrane transport, hydrogen peroxide transmembrane transport, intracellular oxygen homeostasis, intracellular water homeostasis, kidney development, ne...
Does Knockout of Nans in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Nans
cell proliferation
Melanoma Cell Line
Gene: Nans (N-acetylneuraminic acid synthase (sialic acid synthase)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CMP-N-acetylneuraminate biosynthetic process, N-acetylneuraminate biosynthetic process, N-acetylneuraminate metabolic process, carbohydrate biosynthetic pr...
Does Knockout of Cbx2 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Cbx2
response to virus
Microglial Cell Line
Gene: Cbx2 (chromobox 2) Type: protein-coding Summary: This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this g...
Does Knockout of Tmem63c in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Tmem63c
cell proliferation
Colonic Cancer Cell Line
Gene: Tmem63c (transmembrane protein 63c) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glomerular filtration, monoatomic cation transmembrane transport, monoatomic cation transport, monoatomic ion transmembrane transport, monoatomic ion transport; MF: calcium-activated...
Does Knockout of Cox6a2 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Cox6a2
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Cox6a2 (cytochrome c oxidase subunit 6A2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial electron transport, cytochrome c to oxygen, oxidative phosphorylation; MF: enzyme regulator activity, oxidoreductase activity; CC: membrane, mitochondrial inner m...
Does Knockout of Cnep1r1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Cnep1r1
cell proliferation
Colonic Cancer Cell Line
Gene: Cnep1r1 (CTD nuclear envelope phosphatase 1 regulatory subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid metabolic process, positive regulation of triglyceride biosynthetic process, protein localization to nucleus; MF: molecular_function, protein phos...
Does Knockout of Etfdh in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Etfdh
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Etfdh (electron transferring flavoprotein, dehydrogenase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: electron transport chain, fatty acid beta-oxidation using acyl-CoA dehydrogenase, respiratory electron transport chain, response to oxidative stress; MF: 4 iron...
Does Knockout of Cul5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Cul5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cul5 (cullin 5) Type: protein-coding Summary: Enables ubiquitin ligase complex scaffold activity. Involved in proteasome-mediated ubiquitin-dependent protein catabolic process and regulation of neuron migration. Acts upstream of with a negative effect on reelin-mediated signaling pathway. Acts ups...
Does Knockout of Adam20 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Adam20
cell cycle progression
breast epithelium
Gene: Adam20 (a disintegrin and metallopeptidase domain 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: male gonad development, proteolysis; MF: metal ion binding, metalloendopeptidase activity, metallopeptidase activity, molecular_function; CC: external side of plasm...
Does Knockout of Hspd1 in Lymphoma Cell Line causally result in response to chemicals?
1
1,549
Knockout
Hspd1
response to chemicals
Lymphoma Cell Line
Gene: Hspd1 (heat shock protein 1 (chaperonin)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation, B cell proliferation, MyD88-dependent toll-like receptor signaling pathway, T cell activation, adhesion of symbiont to host, apoptotic mitochondrial changes,...
Does Knockout of G6pdx in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
G6pdx
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: G6pdx (glucose-6-phosphate dehydrogenase X-linked) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NADP+ biosynthetic process, NADP+ metabolic process, NADPH regeneration, angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressu...
Does Knockout of Mbtps2 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Mbtps2
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Mbtps2 (membrane-bound transcription factor peptidase, site 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NLS-bearing protein import into nucleus, bone maturation, cholesterol metabolic process, lipid metabolic process, membrane protein intracellular domain pro...
Does Knockout of Caap1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Caap1
cell proliferation
Melanoma Cell Line
Gene: Caap1 (caspase activity and apoptosis inhibitor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, negative regulation of apoptotic process, regulation of apoptotic process Pathways: UniProt: Q8VDY9 Entrez ID: 67770
Does Knockout of Siah2 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Siah2
cell proliferation
Melanoma Cell Line
Gene: Siah2 (siah E3 ubiquitin protein ligase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, canonical Wnt signaling pathway, negative regulation of apoptotic process, negative regulation of canonical Wnt signaling pathway, negative regulation of ex...
Does Knockout of Txn1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Txn1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Txn1 (thioredoxin 1) Type: protein-coding Summary: Enables protein-disulfide reductase activity. Acts upstream of or within cell redox homeostasis; negative regulation of protein export from nucleus; and negative regulation of transcription by RNA polymerase II. Located in cytosol and nucleus. Is ...
Does Knockout of Stxbp3 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Stxbp3
protein/peptide distribution
myoblast cell line
Gene: Stxbp3 (syntaxin binding protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, cellular response to type II interferon, exocytosis, insulin secretion, intracellular glucose homeostasis, intracellular protein transport, negative regulation of ...
Does Knockout of Tuba1a in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Tuba1a
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tuba1a (tubulin, alpha 1A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adult behavior, adult locomotory behavior, cellular response to calcium ion, centrosome cycle, cerebellar cortex morphogenesis, cerebral cortex development, dentate gyrus development, flagell...
Does Knockout of Ccr4 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Ccr4
response to virus
Embryonic Fibroblast Cell Line
Gene: Ccr4 (C-C motif chemokine receptor 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, calcium-mediated signaling, cell chemotaxis, chemokine-mediated signaling pathway, chemotaxis, homeostasis of number of cells, immune ...
Does Knockout of Tmem51 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Tmem51
cell proliferation
Embryonic Stem Cell Line
Gene: Tmem51 (transmembrane protein 51) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q99LG1 Entrez ID: 214359
Does Knockout of Ppp1r3a in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Ppp1r3a
response to virus
Embryonic Fibroblast Cell Line
Gene: Ppp1r3a (protein phosphatase 1, regulatory subunit 3A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glycogen metabolic process, regulation of glycogen biosynthetic process; MF: glycogen binding, protein phosphatase 1 binding, protein serine/threonine phosphatase ...
Does Knockout of Gpn1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Gpn1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Gpn1 (GPN-loop GTPase 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: GTP binding, GTPase activity, hydrolase activity, nucleotide binding; CC: cytoplasm, cytosol, mitochondrion, nucleoplasm, nucleus Pathways: UniProt: Q8VCE2 Entrez ID:...
Does Knockout of Csdc2 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Csdc2
protein/peptide distribution
myoblast cell line
Gene: Csdc2 (cold shock domain containing C2, RNA binding) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA processing, regulation of mRNA stability; MF: RNA binding, mRNA 3'-UTR binding, nucleic acid binding; CC: cytoplasm, nucleus Pathways: UniPro...
Does Knockout of Mfsd2a in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Mfsd2a
cell cycle progression
breast epithelium
Gene: Mfsd2a (MFSD2 lysolipid transporter A, lysophospholipid) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, carbohydrate transport, cellular response to starvation, cognition, embryonic brain development, energy homeostasis, establishment of blood-br...
Does Knockout of Adam7 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Adam7
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Adam7 (a disintegrin and metallopeptidase domain 7) Type: protein-coding Summary: This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. This gene is ...
Does Knockout of Skint6 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Skint6
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Skint6 (selection and upkeep of intraepithelial T cells 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell activation, T cell receptor signaling pathway, regulation of T cell activation, regulation of cytokine production, regulation of leukocyte cell-cell adh...
Does Knockout of Rps26 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Rps26
response to virus
Microglial Cell Line
Gene: Rps26 (ribosomal protein S26) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, negative regulation of RNA splicing, translation, translation at postsynapse, translation at presynapse; MF: mRNA binding, structural constituent of ribosome; CC: ...
Does Knockout of Spaca4 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Spaca4
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Spaca4 (sperm acrosome associated 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: binding of sperm to zona pellucida, cell adhesion, fertilization, single fertilization, sperm-egg recognition; CC: acrosomal vesicle, cytoplasmic vesicle, inner acrosomal membrane, ...
Does Knockout of Uchl1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Uchl1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Uchl1 (ubiquitin carboxy-terminal hydrolase L1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adult walking behavior, axon target recognition, axonal transport of mitochondrion, axonogenesis, cellular response to xenobiotic stimulus, eating behavior, male germ cel...
Does Knockout of Ska3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Ska3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ska3 (spindle and kinetochore associated complex subunit 3) Type: protein-coding Summary: Predicted to enable microtubule binding activity. Involved in establishment of meiotic spindle orientation and spindle assembly involved in female meiosis. Located in meiotic spindle. Is expressed in several ...
Does Knockout of Exog in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Exog
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Exog (exo/endonuclease G) Type: protein-coding Summary: No summary available. Gene Ontology: MF: 5'-3' exonuclease activity, RNA endonuclease activity, endonuclease activity, hydrolase activity, metal ion binding, nuclease activity, nucleic acid binding, single-stranded DNA endodeoxyribon...
Does Knockout of Naaladl1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Naaladl1
cell proliferation
Embryonic Stem Cell Line
Gene: Naaladl1 (N-acetylated alpha-linked acidic dipeptidase-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: peptide catabolic process, proteolysis; MF: aminopeptidase activity, calcium ion binding, carboxypeptidase activity, hydrolase activity, metal ion binding,...
Does Knockout of Ipmk in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ipmk
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ipmk (inositol polyphosphate multikinase) Type: protein-coding Summary: Enables inositol-1,4,5,6-tetrakisphosphate 3-kinase activity and inositol-1,4,5-trisphosphate 3-kinase activity. Acts upstream of or within inositol phosphate biosynthetic process and neural tube formation. Predicted to be loc...
Does Knockout of Myl12a in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Myl12a
protein/peptide distribution
myoblast cell line
Gene: Myl12a (myosin, light chain 12A, regulatory, non-sarcomeric) Type: protein-coding Summary: Enables glutamate receptor binding activity. Acts upstream of or within protein localization to plasma membrane and regulation of cell shape. Located in Z disc and stress fiber. Part of myosin II complex. Or...
Does Knockout of Pkn1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Pkn1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Pkn1 (protein kinase N1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell apoptotic process, B cell homeostasis, chromatin organization, chromatin remodeling, epithelial cell migration, hyperosmotic response, intracellular signal transduction, negative regulat...
Does Knockout of Oip5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Oip5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Oip5 (Opa interacting protein 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CENP-A containing chromatin assembly, cell division, chromosome segregation, pericentric heterochromatin organization; MF: identical protein binding, metal ion binding; CC: CENP-A recru...
Does Knockout of Ints11 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,440
Knockout
Ints11
protein/peptide accumulation
Embryonic Cell Line
Gene: Ints11 (integrator complex subunit 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II transcription initiation surveillance, snRNA 3'-end processing, snRNA processing, transcription by RNA polymerase II, transcription elongation by RNA polymerase ...
Does Knockout of Trmt112 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Trmt112
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Trmt112 (tRNA methyltransferase 11-2) Type: protein-coding Summary: Predicted to enable protein heterodimerization activity; protein methyltransferase activity; and tRNA methyltransferase activator activity. Involved in peptidyl-glutamine methylation. Predicted to be located in nucleoplasm and per...
Does Knockout of Zranb1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Zranb1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Zranb1 (zinc finger, RAN-binding domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, autophagosome assembly, cell migration, cytoskeleton organization, phosphatidylinositol phosphate biosynthetic process, positive regulation o...
Does Knockout of Sdf2 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Sdf2
cell proliferation
Regulatory T cell
Gene: Sdf2 (stromal cell derived factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein refolding; MF: misfolded protein binding; CC: endoplasmic reticulum, extracellular region, protein folding chaperone complex, protein-containing complex Pathways: ...
Does Knockout of Ppp1r35 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Ppp1r35
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Ppp1r35 (protein phosphatase 1, regulatory subunit 35) Type: protein-coding Summary: No summary available. Gene Ontology: BP: notochord morphogenesis, positive regulation of centriole elongation, positive regulation of cilium assembly; MF: phosphatase binding, protein phosphatase inhibito...
Does Knockout of Dtl in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Dtl
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dtl (denticleless E3 ubiquitin protein ligase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA replication, mitotic G2 DNA damage checkpoint signaling, positive regulation of G2/M transition of mitotic cell cycle, positive regulation of cata...
Does Knockout of Myg1 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Myg1
response to virus
Embryonic Fibroblast Cell Line
Gene: Myg1 (melanocyte proliferating gene 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: locomotory exploration behavior, mRNA processing, mitochondrial RNA metabolic process, rRNA processing; MF: 3'-5'-RNA exonuclease activity, hydrolase activity, molecular_function,...
Does Knockout of Rpl35a in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Rpl35a
cell proliferation
Colonic Cancer Cell Line
Gene: Rpl35a (ribosomal protein L35A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, rRNA processing, ribosomal large subunit biogenesis, translation, translation at postsynapse, translation at presynapse; MF: ribonucleoprotein complex binding, s...
Does Knockout of Tm4sf1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Tm4sf1
cell proliferation
Embryonic Stem Cell Line
Gene: Tm4sf1 (transmembrane 4 superfamily member 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane, plasma membrane Pathways: UniProt: Q64302 Entrez ID: 17112
Does Activation of Dnajc19 in Mouse cell causally result in protein/peptide accumulation?
1
690
Activation
Dnajc19
protein/peptide accumulation
Mouse cell
Gene: Dnajc19 (DnaJ heat shock protein family (Hsp40) member C19) Type: protein-coding Summary: No summary available. Gene Ontology: BP: genitalia development, protein import into mitochondrial matrix, protein transport, regulation of cardiolipin metabolic process, visual perception; MF: ATPase...
Does Knockout of Kdm1a in Melanoma Cell Line causally result in cell proliferation?
1
1,157
Knockout
Kdm1a
cell proliferation
Melanoma Cell Line
Gene: Kdm1a (lysine (K)-specific demethylase 1A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair-dependent chromatin remodeling, cell differentiation, cellular response to UV, cellular response to gamma radiation, chromatin organization, epigenetic regulation o...