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Does Knockout of Dmrtb1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Dmrtb1
autophagy
Embryonic Fibroblast Cell Line
Gene: Dmrtb1 (DMRT-like family B with proline-rich C-terminal, 1) Type: protein-coding Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regula...
Does Knockout of Spag4 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Spag4
cell proliferation
Colonic Cancer Cell Line
Gene: Spag4 (sperm associated antigen 4) Type: protein-coding Summary: Predicted to enable identical protein binding activity and protein-membrane adaptor activity. Predicted to be involved in cell differentiation and spermatogenesis. Predicted to be located in microtubule. Predicted to be part of meiot...
Does Knockout of Agtr2 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Agtr2
response to chemicals
Pancreatic Cancer Cell Line
Gene: Agtr2 (angiotensin II receptor, type 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger, angiotensin-activated signaling pathway, a...
Does Knockout of Slx4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Slx4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Slx4 (SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)) Type: protein-coding Summary: This gene encodes a protein containing a BTB (POZ) domain that comprises a subunit of structure-specific endonucleases. The encoded protein aids in the resolution of DNA secondary structures t...
Does Knockout of Fbxw13 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Fbxw13
cell proliferation
Melanoma Cell Line
Gene: Fbxw13 (F-box and WD-40 domain protein 13) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, cytoplasm Pathways: UniProt: A0A0G2JDF9, Q8BI57, A0A0G2JFH5 Entrez ID: 211305
Does Knockout of Clns1a in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Clns1a
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Clns1a (chloride channel, nucleotide-sensitive, 1A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, cell volume homeostasis, chloride transport, mRNA cis splicing, via spliceosome, mRNA processing, negative regulation of cell volume, positive regulatio...
Does Knockout of Cand1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Cand1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Cand1 (cullin associated and neddylation disassociated 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: SCF complex assembly, cell differentiation, negative regulation of catalytic activity, positive regulation of DNA-templated transcription, positive regulation o...
Does Knockout of Nans in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Nans
protein/peptide distribution
myoblast cell line
Gene: Nans (N-acetylneuraminic acid synthase (sialic acid synthase)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CMP-N-acetylneuraminate biosynthetic process, N-acetylneuraminate biosynthetic process, N-acetylneuraminate metabolic process, carbohydrate biosynthetic pr...
Does Knockout of Hcfc1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Hcfc1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Hcfc1 (host cell factor C1) Type: protein-coding Summary: This gene encodes a transcription cofactor that regulates the progression of cell cycle and maintain the ability of embryonic stem cells to self-renew. The encoded protein is a large precursor that undergoes site-specific proteolytic cleava...
Does Knockout of Cnot7 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Cnot7
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cnot7 (CCR4-NOT transcription complex, subunit 7) Type: protein-coding Summary: Enables piRNA binding activity and poly(A)-specific ribonuclease activity. Involved in positive regulation of mRNA catabolic process and spermatogenesis. Acts upstream of or within P-body assembly and positive regulati...
Does Knockout of Tpt1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Tpt1
cell proliferation
Colonic Cancer Cell Line
Gene: Tpt1 (tumor protein, translationally-controlled 1) Type: protein-coding Summary: Enables DNA-binding transcription factor binding activity. Involved in negative regulation of ectoderm development and stem cell population maintenance. Located in nucleoplasm. Is expressed in cerebral cortex ventricu...
Does Knockout of Smarce1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Smarce1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Smarce1 (SWI/SNF related BAF chromatin remodeling complex subunit E1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, negative regulation of DNA-templated transcription, nervous system development, neurogenesis, nucleoso...
Does Knockout of Dnmbp in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Dnmbp
protein/peptide distribution
myoblast cell line
Gene: Dnmbp (dynamin binding protein) Type: protein-coding Summary: This gene encodes a member of the DBL family of guanine nucleotide exchange factors. The encoded protein has been proposed to regulate the actin cytoskeleton by specifically activating the Rho-family GTPase Cdc42. An interaction between...
Does Knockout of Slc25a51 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Slc25a51
protein/peptide distribution
myoblast cell line
Gene: Slc25a51 (solute carrier family 25, member 51) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NAD+ biosynthetic process via the salvage pathway, NADP+ biosynthetic process, aerobic electron transport chain, mitochondrial NAD transmembrane transport, nicotinamide ri...
Does Knockout of Brap in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,171
Knockout
Brap
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Brap (BRCA1 associated protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, Ras protein signal transduction, negative regulation of signal transduction, protein ubiquitination; MF: identical protein binding, metal ion binding, nuclear localization ...
Does Knockout of Wdr59 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Wdr59
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Wdr59 (WD repeat domain 59) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to amino acid starvation, cellular response to nutrient levels, positive regulation of TORC1 signaling, protein localization to plasma membrane; MF: metal ion binding, mole...
Does Knockout of Nfyb in Embryonic Stem Cell Line causally result in cell proliferation?
1
578
Knockout
Nfyb
cell proliferation
Embryonic Stem Cell Line
Gene: Nfyb (nuclear transcription factor-Y beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to leukemia inhibitory factor, positive regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II, regulation of D...
Does Knockout of Pgghg in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Pgghg
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Pgghg (protein glucosylgalactosylhydroxylysine glucosidase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate metabolic process; MF: catalytic activity, hydrolase activity, hydrolase activity, acting on glycosyl bonds, protein-glucosylgalactosylhydroxylys...
Does Knockout of 4933428G20Rik in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
4933428G20Rik
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: 4933428G20Rik (RIKEN cDNA 4933428G20 gene) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Ric8a in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Ric8a
response to virus
Microglial Cell Line
Gene: Ric8a (RIC8 guanine nucleotide exchange factor A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, basement membrane organization, cell migration ...
Does Knockout of Pkmyt1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Pkmyt1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pkmyt1 (protein kinase, membrane associated tyrosine/threonine 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: meiotic cell cycle, negative regulation of G2/M transition of mitotic cell cycle, negative regulation of G2/MI transition of meiotic cell cycle; MF: ATP...
Does Knockout of Ckap2l in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ckap2l
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ckap2l (cytoskeleton associated protein 2-like) Type: protein-coding Summary: No summary available. Gene Ontology: CC: centrosome, cilium, cytoplasm, cytoskeleton, cytosol, microtubule cytoskeleton, mitotic spindle, spindle pole Pathways: UniProt: Q7TS74 Entrez ...
Does Knockout of Stard5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Stard5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Stard5 (StAR related lipid transfer domain containing 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cholesterol import, lipid transport; MF: cholesterol binding, cholesterol transfer activity, lipid binding Pathways: Bile acid and bile salt metabolism,...
Does Knockout of Ifna5 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Ifna5
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Ifna5 (interferon alpha 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation involved in immune response, T cell activation involved in immune response, adaptive immune response, defense response, defense response to virus, humoral immune response, n...
Does Knockout of Tmprss11c in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Tmprss11c
protein/peptide distribution
myoblast cell line
Gene: Tmprss11c (transmembrane protease, serine 11c) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteolysis, self proteolysis; MF: hydrolase activity, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity; CC: cell projection, dendrit...
Does Knockout of Snrpa1 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Snrpa1
response to virus
Microglial Cell Line
Gene: Snrpa1 (small nuclear ribonucleoprotein polypeptide A') Type: protein-coding Summary: Predicted to enable U2 snRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome and spermatogenesis. Predicted to be located in nuclear speck. Predicted to be part of U2 snRNP; U2-type c...
Does Knockout of Abcb8 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Abcb8
protein/peptide accumulation
Mouse cell
Gene: Abcb8 (ATP-binding cassette, sub-family B member 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell volume homeostasis, mitochondrial potassium ion transmembrane transport, monoatomic ion transport, potassium ion transmembrane transport, potassium ion transport...
Does Knockout of 4933405O20Rik in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
4933405O20Rik
cell viability
Immortal mouse chromaffin cells
Gene: 4933405O20Rik (RIKEN cDNA 4933405O20 gene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: isocitrate metabolic process, tricarboxylic acid cycle; MF: ATP binding, magnesium ion binding, metal ion binding, nucleotide binding; CC: mitochondrion Pathways: Cit...
Does Knockout of Ifitm10 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Ifitm10
protein/peptide distribution
myoblast cell line
Gene: Ifitm10 (interferon induced transmembrane protein 10) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane, plasma membrane Pathways: UniProt: Q8BR26 Entrez ID: 320802
Does Knockout of Agtpbp1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Agtpbp1
protein/peptide accumulation
Regulatory T cell
Gene: Agtpbp1 (ATP/GTP binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: C-terminal protein deglutamylation, adult walking behavior, anterograde axonal transport of mitochondrion, axonal transport, central nervous system neuron development, cerebellar Pur...
Does Knockout of Riox1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Riox1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Riox1 (ribosomal oxygenase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, negative regulation of DNA repair, negative regulation of DNA-templated transcription, negative regulation of osteoblast differentiation, regu...
Does Knockout of Atp6v0e2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Atp6v0e2
cell viability
Immortal mouse chromaffin cells
Gene: Atp6v0e2 (ATPase, H+ transporting, lysosomal V0 subunit E2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transport, proton transmembrane transport, synaptic vesicle lumen acidification, transmembrane transport; MF: proton-transporting ATPase activi...
Does Knockout of Gpt2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Gpt2
protein/peptide accumulation
Embryonic Cell Line
Gene: Gpt2 (glutamic pyruvate transaminase (alanine aminotransferase) 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 2-oxoglutarate metabolic process, L-alanine catabolic process, L-alanine metabolic process, gluconeogenesis; MF: L-alanine:2-oxoglutarate aminotransfer...
Does Knockout of Rbm20 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Rbm20
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rbm20 (RNA binding motif protein 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, heart formation, mRNA processing, negative regulation of mRNA splicing, via spliceosome, positive regulation of RNA splicing, regulation of RNA splicing, regulation of...
Does Knockout of Nufip1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
578
Knockout
Nufip1
cell proliferation
Embryonic Stem Cell Line
Gene: Nufip1 (nuclear FMR1 interacting protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: box C/D snoRNP assembly, positive regulation of transcription by RNA polymerase II; MF: ATPase binding, RNA binding, identical protein binding, metal ion binding, protein bin...
Does Knockout of Zfp958 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Zfp958
protein/peptide distribution
myoblast cell line
Gene: Zfp958 (zinc finger protein 958) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of cytokine production, regulation of gene expression, regulation of imm...
Does Knockout of Tmc1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Tmc1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tmc1 (transmembrane channel-like gene family 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: auditory receptor cell development, calcium ion transmembrane transport, detection of mechanical stimulus involved in sensory perception of sound, monoatomic ion transmem...
Does Knockout of Lhfpl3 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Lhfpl3
protein/peptide distribution
myoblast cell line
Gene: Lhfpl3 (lipoma HMGIC fusion partner-like 3) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane, plasma membrane Pathways: UniProt: Q9CTN8 Entrez ID: 269629
Does Knockout of Gm5148 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Gm5148
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gm5148 (predicted gene 5148) Type: protein-coding Summary: predicted gene 5148 Gene Ontology: Pathways: UniProt: Q8BGG2 Entrez ID: 381438
Does Knockout of Tsr2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Tsr2
cell proliferation
Embryonic Stem Cell Line
Gene: Tsr2 (TSR2 20S rRNA accumulation) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA processing Pathways: UniProt: Q8C8T8 Entrez ID: 69499
Does Knockout of Cables2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Cables2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cables2 (CDK5 and Abl enzyme substrate 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, cell division, regulation of cell cycle; CC: cellular_component, cytosol Pathways: UniProt: Q8K3M5 Entrez ID: 252966
Does Knockout of Ccdc71 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Ccdc71
cell proliferation
Mouse kidney carcinoma cell
Gene: Ccdc71 (coiled-coil domain containing 71) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8VEG0 Entrez ID: 72454
Does Knockout of Ptpn5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ptpn5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ptpn5 (protein tyrosine phosphatase, non-receptor type 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: exploration behavior, positive regulation of long-term synaptic potentiation, positive regulation of neuron projection development, positive regulation of prote...
Does Knockout of Ftsj3 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Ftsj3
protein/peptide distribution
myoblast cell line
Gene: Ftsj3 (FtsJ RNA 2'-O-methyltransferase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA methylation, maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, ...
Does Knockout of Zfp438 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Zfp438
protein/peptide distribution
myoblast cell line
Gene: Zfp438 (zinc finger protein 438) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, DNA-binding transcripti...
Does Knockout of Ogfod2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Ogfod2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ogfod2 (2-oxoglutarate and iron-dependent oxygenase domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: L-ascorbic acid binding, dioxygenase activity, iron ion binding, metal ion binding, molecular_function, oxidoreductase activity, oxidoreductase a...
Does Knockout of Arhgap19 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Arhgap19
protein/peptide distribution
myoblast cell line
Gene: Arhgap19 (Rho GTPase activating protein 19) Type: protein-coding Summary: Predicted to enable GTPase activator activity. Predicted to be involved in regulation of small GTPase mediated signal transduction. Predicted to be located in intracellular membrane-bounded organelle and plasma membrane. Pre...
Does Knockout of Gspt1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Gspt1
cell proliferation
Embryonic Stem Cell Line
Gene: Gspt1 (G1 to S phase transition 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, regulation of translational termination, ribosome disassembly, translation, translational termination; MF: GTP bin...
Does Knockout of Pou4f3 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Pou4f3
cell proliferation
Embryonic Stem Cell Line
Gene: Pou4f3 (POU domain, class 4, transcription factor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, axon extension, cell differentiation, inner ear auditory receptor cell differentiation, inner ear development, inner ear morphogenesis, inner ear ...
Does Knockout of Rbbp7 in Lung Cancer Cell Line causally result in tumorigenicity?
0
1,089
Knockout
Rbbp7
tumorigenicity
Lung Cancer Cell Line
Gene: Rbbp7 (retinoblastoma binding protein 7, chromatin remodeling factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, brain development, cellular heat acclimation, chromatin organization, chromatin remodeling, negative regulation of DNA-templated tr...
Does Knockout of Ankrd13a in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Ankrd13a
protein/peptide distribution
myoblast cell line
Gene: Ankrd13a (ankyrin repeat domain 13a) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of protein localization to endosome, negative regulation of receptor internalization; MF: ubiquitin-modified protein reader activity; CC: cytoplasm, endosome, la...
Does Knockout of Bpifb3 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Bpifb3
protein/peptide distribution
myoblast cell line
Gene: Bpifb3 (BPI fold containing family B, member 3) Type: protein-coding Summary: No summary available. Gene Ontology: MF: lipid binding, molecular_function; CC: cytoplasm, extracellular region Pathways: UniProt: Q80ZU7 Entrez ID: 378700
Does Knockout of Gins3 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,287
Knockout
Gins3
cell proliferation
Mouse kidney carcinoma cell
Gene: Gins3 (GINS complex subunit 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, cellular senescence, multicellular organism growth; CC: CMG complex, GINS complex, chromosome, nucleoplasm, nucleus Pathways: Cell Cycle, Cell Cycle, Mitotic, DN...
Does Knockout of Ubox5 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Ubox5
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ubox5 (U box domain containing 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein polyubiquitination, protein ubiquitination; MF: metal ion binding, transferase activity, ubiquitin protein ligase activity, ubiquitin protein ligase binding, ubiquitin-protein ...
Does Knockout of Prss33 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Prss33
autophagy
Embryonic Fibroblast Cell Line
Gene: Prss33 (serine protease 33) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteolysis; MF: hydrolase activity, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity; CC: cytoplasm, extracellular region, extracellular space ...
Does Knockout of Drap1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Drap1
cell proliferation
Embryonic Stem Cell Line
Gene: Drap1 (DR1 associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, transcription by RNA polymerase II; MF: DNA binding, RNA polymerase II general transcription initiation factor activity, RNA p...
Does Knockout of Pi4ka in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Pi4ka
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Pi4ka (phosphatidylinositol 4-kinase alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Schwann cell migration, actin cytoskeleton organization, host-mediated perturbation of viral process, lipid metabolic process, myelination in peripheral nervous system, phosp...
Does Knockout of Cacna2d4 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Cacna2d4
protein/peptide distribution
Microglial Cell Line
Gene: Cacna2d4 (calcium channel, voltage-dependent, alpha 2/delta subunit 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion transmembrane transport, calcium ion transport, detection of light stimulus involved in visual perception, monoatomic ion transmembrane...
Does Knockout of Muc19 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Muc19
protein/peptide distribution
Microglial Cell Line
Gene: Muc19 (mucin 19) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, B cell proliferation, T cell differentiation, T cell proliferation, antibacterial innate immune response, cell differentiation involved in salivary gland development, chemokine-...
Does Knockout of Lats2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Lats2
cell proliferation
Mouse kidney carcinoma cell
Gene: Lats2 (large tumor suppressor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G1/S transition of mitotic cell cycle, cell division, hippo signaling, hormone-mediated signaling pathway, inner cell mass cell fate commitment, inner cell mass cellular morphogenesis, ...
Does Knockout of Chaf1b in Lymphoma Cell Line causally result in response to chemicals?
1
1,544
Knockout
Chaf1b
response to chemicals
Lymphoma Cell Line
Gene: Chaf1b (chromatin assembly factor 1, subunit B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, DNA replication-dependent chromatin assembly, chromatin organization, nucleosome assembly; CC: CAF-1 complex, chromatin,...
Does Knockout of Il23a in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Il23a
cell proliferation
Embryonic Stem Cell Line
Gene: Il23a (interleukin 23, alpha subunit p19) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell proliferation, cell surface receptor signaling pathway via JAK-STAT, cell surface receptor signaling pathway via STAT, defense response to Gram-negative bacterium, defen...
Does Knockout of Psmb6 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Psmb6
cell proliferation
Mouse kidney carcinoma cell
Gene: Psmb6 (proteasome (prosome, macropain) subunit, beta type 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis, proteolysis involved in protein catabolic process; MF: endopeptidase activity...
Does Knockout of Atr in Lymphoma Cell Line causally result in response to chemicals?
1
1,540
Knockout
Atr
response to chemicals
Lymphoma Cell Line
Gene: Atr (ataxia telangiectasia and Rad3 related) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage checkpoint signaling, DNA damage response, DNA repair, DNA replication, DNA strand resection involved in replication fork processing, G2/M transition of mitotic c...
Does Knockout of Phf13 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Phf13
cell proliferation
Colonic Cancer Cell Line
Gene: Phf13 (PHD finger protein 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, cell division, chromatin organization, chromosome condensation, chromosome segregation, mitotic cell cycle, mitotic chromosome condensation; MF: chromatin binding, chr...
Does Knockout of Rps5 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Rps5
cell proliferation
Colonic Cancer Cell Line
Gene: Rps5 (ribosomal protein S5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, regulation of translational fidelity, ribosomal small subunit biogenesis, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, mRNA b...
Does Knockout of Dazap1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Dazap1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Dazap1 (DAZ associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, fibroblast proliferation, maternal placenta development, positive regulation of mRNA splicing, via spliceosome, spermatogenesis; MF: RNA binding, RNA stem-loop bi...
Does Knockout of Actn1 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Actn1
protein/peptide distribution
myoblast cell line
Gene: Actn1 (actinin, alpha 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, actin filament bundle assembly, actin filament network formation, actin filament organization, cortical cytoskeleton organization, focal adhesion assembly, musc...
Does Knockout of Dnlz in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Dnlz
autophagy
Embryonic Fibroblast Cell Line
Gene: Dnlz (DNL-type zinc finger) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chaperone-mediated protein complex assembly, protein folding, protein import into mitochondrial matrix, protein stabilization; MF: metal ion binding, protein folding chaperone, protein-foldi...
Does Knockout of Serpina9 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Serpina9
response to virus
Embryonic Fibroblast Cell Line
Gene: Serpina9 (serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9) Type: protein-coding Summary: No summary available. Gene Ontology: MF: peptidase inhibitor activity, serine-type endopeptidase inhibitor activity; CC: extracellular region, extrace...
Does Knockout of Srrm1 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Srrm1
protein/peptide distribution
myoblast cell line
Gene: Srrm1 (serine/arginine repetitive matrix 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, RNA splicing, via transesterification reactions, mRNA processing, mRNA splicing, via spliceosome, regulation of mRNA splicing, via spliceosome; MF: DNA binding,...
Does Knockout of Trdn in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Trdn
protein/peptide accumulation
Embryonic Cell Line
Gene: Trdn (triadin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic microtubule organization, endoplasmic reticulum membrane organization, establishment of localization in cell, heart contraction, intracellular calcium ion homeostasis, negative regulation of ...
Does Knockout of Vmp1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Vmp1
cell proliferation
Colonic Cancer Cell Line
Gene: Vmp1 (vacuole membrane protein 1) Type: protein-coding Summary: Predicted to enable phospholipid scramblase activity. Involved in autophagy and lipoprotein transport. Acts upstream of or within embryo implantation. Located in phagophore assembly site. Orthologous to human VMP1 (vacuole membrane pr...
Does Knockout of Ang2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Ang2
protein/peptide accumulation
Embryonic Cell Line
Gene: Ang2 (angiogenin, ribonuclease A family, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, angiotensin-activated signaling pathway, antibacterial humoral response, antifungal humoral response, antimicrobial humoral immune response mediated by a...
Does Knockout of Haus2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Haus2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Haus2 (HAUS augmin-like complex, subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, centrosome cycle, microtubule nucleation, microtubule organizing center organization, spindle assembly; CC: HAUS complex, centrosome, cytoplasm, cytoskeleton, ...
Does Knockout of Prg4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Prg4
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Prg4 (proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: hematopoietic stem cell proliferation, immune response, negative regulation of interleukin-6 production, regulation of cell p...
Does Knockout of Ms4a1 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Ms4a1
response to virus
Microglial Cell Line
Gene: Ms4a1 (membrane-spanning 4-domains, subfamily A, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation, B cell differentiation, B cell receptor signaling pathway, calcium ion import into cytosol, cell surface receptor signaling pathway, positiv...
Does Knockout of Oas1e in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Oas1e
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Oas1e (2'-5' oligoadenylate synthetase 1E) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antiviral innate immune response, cellular response to exogenous dsRNA, cellular response to interferon-alpha, cellular response to interferon-beta, defense response to bacter...
Does Knockout of Il2rb in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Il2rb
protein/peptide accumulation
Mouse cell
Gene: Il2rb (interleukin 2 receptor, beta chain) Type: protein-coding Summary: The interleukin 2 receptor is composed of alpha and beta subunits. The beta subunit encoded by this gene is very homologous to the human beta subunit and also shows structural similarity to other cytokine receptors. [provided...
Does Knockout of Yipf7 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Yipf7
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Yipf7 (Yip1 domain family, member 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, endoplasmic reticulum to Golgi vesicle-mediated transport, vesicle fusion with Golgi apparatus; CC: Golgi apparatus, cis-Golgi network, endomembrane system, endo...
Does Knockout of Tmem184b in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Tmem184b
cell proliferation
Embryonic Stem Cell Line
Gene: Tmem184b (transmembrane protein 184b) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane Pathways: UniProt: Q8BG09 Entrez ID: 223693
Does Knockout of Ngdn in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Ngdn
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ngdn (neuroguidin, EIF4E binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), negative regulation of protein localization to plasma membrane, postsynaptic modulatio...
Does Knockout of Nop53 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Nop53
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nop53 (NOP53 ribosome biogenesis factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, cellular response to hypoxia, mitotic G2 DNA damage checkpoint signaling, negative regulation of phosphatidylinositol 3-kinase/protein kinase B ...
Does Knockout of Tlr5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Tlr5
cell proliferation
Mouse kidney carcinoma cell
Gene: Tlr5 (toll-like receptor 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: immune response, immune system process, inflammatory response, innate immune response, positive regulation of cytokine production, positive regulation of interleukin-8 production, positive r...
Does Knockout of Iah1 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Iah1
response to virus
Embryonic Fibroblast Cell Line
Gene: Iah1 (isoamyl acetate-hydrolyzing esterase 1 homolog) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, gene expression, lipid catabolic process, lipid metabolic process; MF: hydrolase activity, hydrolase activity, acting on ester bonds, identical ...
Does Knockout of Magi1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Magi1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Magi1 (membrane associated guanylate kinase, WW and PDZ domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endothelial cell morphogenesis, positive regulation of cell-cell adhesion, signal transduction; MF: ATP binding, alpha-actinin binding, nucle...
Does Knockout of Ikbkg in Melanoma Cell Line causally result in tumorigenicity?
0
616
Knockout
Ikbkg
tumorigenicity
Melanoma Cell Line
Gene: Ikbkg (inhibitor of kappaB kinase gamma) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell homeostasis, DNA damage response, anoikis, canonical NF-kappaB signal transduction, defense response to bacterium, establishment of vesicle localization, negative regulat...
Does Knockout of Cdx4 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Cdx4
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cdx4 (caudal type homeobox 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterior/posterior axis specification, anterior/posterior pattern specification, blood vessel development, cell differentiation, digestive tract development, embryonic pattern specificatio...
Does Knockout of Pcdhb4 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Pcdhb4
phagocytosis
macrophage
Gene: Pcdhb4 (protocadherin beta 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding, molecular_function; CC: membrane, plasma membrane ...
Does Knockout of Ubxn4 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Ubxn4
cell cycle progression
breast epithelium
Gene: Ubxn4 (UBX domain protein 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, response to unfolded protein; CC: cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, membrane, nuclear envelope, nucleus Pathways: Protein processing in ...
Does Knockout of Gria2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Gria2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gria2 (glutamate receptor, ionotropic, AMPA2 (alpha 2)) Type: protein-coding Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of g...
Does Knockout of Ndufa6 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Ndufa6
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Ndufa6 (NADH:ubiquinone oxidoreductase subunit A6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, mitochondrial respiratory chain complex I assembly, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner memb...
Does Knockout of Ccdc137 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Ccdc137
phagocytosis
macrophage
Gene: Ccdc137 (coiled-coil domain containing 137) Type: protein-coding Summary: No summary available. Gene Ontology: CC: chromosome, nucleolus, nucleoplasm, nucleus Pathways: UniProt: Q8R0K4 Entrez ID: 67291
Does Knockout of Mrpl48 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Mrpl48
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mrpl48 (mitochondrial ribosomal protein L48) Type: protein-coding Summary: No summary available. Gene Ontology: CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrial ribosome, mitochondrion, ribonucleoprotein complex, ribosome Pathways: Metabolism...
Does Knockout of Dap3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Dap3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Dap3 (death associated protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic mitochondrial changes, apoptotic process, mitochondrial translation; MF: GTPase activity, hydrolase activity, structural constituent of ribosome; CC: mitochondrial inner memb...
Does Knockout of Rpl3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Rpl3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Rpl3 (ribosomal protein L3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to interleukin-4, cytoplasmic translation, translation; MF: 5S rRNA binding, RNA binding, structural constituent of ribosome; CC: cytoplasm, cytosol, cytosolic large riboso...
Does Knockout of Mrps22 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Mrps22
cell proliferation
Colonic Cancer Cell Line
Gene: Mrps22 (mitochondrial ribosomal protein S22) Type: protein-coding Summary: No summary available. Gene Ontology: MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondrion, ribonucleoprotein complex, ribosome Path...
Does Knockout of Faim in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Faim
protein/peptide distribution
myoblast cell line
Gene: Faim (Fas apoptotic inhibitory molecule) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, negative regulation of apoptotic process, negative regulation of extrinsic apoptotic signaling pathway via death domain receptors, positive regulation of cano...
Does Knockout of Tppp in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Tppp
cell viability
Immortal mouse chromaffin cells
Gene: Tppp (tubulin polymerization promoting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: astral microtubule organization, cell division, microtubule bundle formation, microtubule nucleation by microtubule organizing center, microtubule polymerization, myelin ...
Does Knockout of Cpne7 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Cpne7
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cpne7 (copine VII) Type: protein-coding Summary: Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encodes a calcium-dependent protein containing two N-terminal type II C2 domains an...