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Does Knockout of Scnm1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Scnm1
cell proliferation
Embryonic Stem Cell Line
Gene: Scnm1 (sodium channel modifier 1) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Zfp454 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Zfp454
cell proliferation
Embryonic Stem Cell Line
Gene: Zfp454 (zinc finger protein 454) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Lrfn3 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Lrfn3
protein/peptide distribution
myoblast cell line
Gene: Lrfn3 (leucine rich repeat and fibronectin type III domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, regulation of presynapse assembly, regulation of synaptic membrane adhesion, synaptic membrane adhesion; CC: axon, cell projection...
Does Knockout of Rab11fip4 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Rab11fip4
protein/peptide accumulation
Mouse cell
Gene: Rab11fip4 (RAB11 family interacting protein 4 (class II)) Type: protein-coding Summary: Predicted to enable protein homodimerization activity and small GTPase binding activity. Predicted to be involved in endocytic recycling and regulation of cytokinesis. Predicted to be located in endosome. Predi...
Does Knockout of Vps11 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Vps11
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Vps11 (VPS11, CORVET/HOPS core subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagy, endosomal vesicle fusion, endosome organization, endosome to lysosome transport, intracellular protein transport, negative regulation of intracellular estrogen recepto...
Does Knockout of Rnf4 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Rnf4
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Rnf4 (ring finger protein 4) Type: protein-coding Summary: This gene encodes a small nuclear RING finger protein that mediates ubiquitylation of polysumoylated proteins. Deficiency of the encoded protein in mice leads to embryonic lethality and global DNA hypermethylation. A similar protein in hum...
Does Knockout of Pgm3 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Pgm3
cell proliferation
Embryonic Stem Cell Line
Gene: Pgm3 (phosphoglucomutase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: UDP-N-acetylglucosamine biosynthetic process, carbohydrate metabolic process, hemopoiesis, protein N-linked glycosylation, protein O-linked glycosylation, spermatogenesis; MF: intramolecular...
Does Knockout of Mcph1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Mcph1
cell proliferation
Embryonic Stem Cell Line
Gene: Mcph1 (microcephaly, primary autosomal recessive 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bone development, cerebral cortex development, establishment of mitotic spindle orientation, mitotic cell cycle, negative regulation of transcription by RNA polymeras...
Does Knockout of Ager in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Ager
protein/peptide distribution
Microglial Cell Line
Gene: Ager (advanced glycosylation end product-specific receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, astrocyte activation, astrocyte development, cell adhesion, cell surface receptor signaling pathway via JAK-...
Does Knockout of Cdca5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Cdca5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cdca5 (cell division cycle associated 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, double-strand break repair, mitotic sister chromatid cohesion; MF: protein binding, protein-containing complex binding; CC: chromatin, chromosome, cytoplasm, nucl...
Does Knockout of Pcmtd1 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Pcmtd1
phagocytosis
macrophage
Gene: Pcmtd1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein ubiquitination; MF: S-adenosylmethionine-dependent methyltransferase activity, protein-L-isoaspartate (D-aspartate) O-methyl...
Does Knockout of Fcgr1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Fcgr1
protein/peptide accumulation
Embryonic Cell Line
Gene: Fcgr1 (Fc receptor, IgG, high affinity I) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Fc-gamma receptor signaling pathway, antibody-dependent cellular cytotoxicity, antigen processing and presentation of exogenous antigen, antigen processing and presentation of ...
Does Knockout of Nudcd1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Nudcd1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Nudcd1 (NudC domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, cytosol, nucleoplasm, nucleus Pathways: UniProt: Q6PIP5 Entrez ID: 67429
Does Knockout of Ankrd17 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Ankrd17
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ankrd17 (ankyrin repeat domain 17) Type: protein-coding Summary: This gene encodes a protein with ankyrin repeats, which are associated with protein-protein interactions. Studies suggest that this protein is involved in liver development. Two transcript variants encoding different isoforms have be...
Does Knockout of Mrpl54 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Mrpl54
cell proliferation
Mouse kidney carcinoma cell
Gene: Mrpl54 (mitochondrial ribosomal protein L54) Type: protein-coding Summary: Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including brain; brown fat; early conceptus; gonad; ...
Does Knockout of Etv5 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Etv5
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Etv5 (ets variant 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cellular response to oxidative stress, locomotory behavior, male germ-line stem cell asymmetric division, negative regulation of transcription by RNA polymerase II, neuromuscu...
Does Knockout of Mmp9 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Mmp9
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Mmp9 (matrix metallopeptidase 9) Type: protein-coding Summary: This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. The encoded preproprot...
Does Knockout of Cep70 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Cep70
cell proliferation
Melanoma Cell Line
Gene: Cep70 (centrosomal protein 70) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, cilium assembly, regulation of microtubule cytoskeleton organization; MF: gamma-tubulin binding, identical protein binding, molecular_function; CC: centrosome, cytopla...
Does Knockout of Bccip in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Bccip
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Bccip (BRCA2 and CDKN1A interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, establishment of mitotic spindle orientation, microtubule anchoring, microtubule cytoskeleton organization, mitotic spindle assembly, mitoti...
Does Knockout of Rad23b in Lymphoma Cell Line causally result in response to chemicals?
0
1,541
Knockout
Rad23b
response to chemicals
Lymphoma Cell Line
Gene: Rad23b (RAD23 homolog B, nucleotide excision repair protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, UV-damage excision repair, cellular response to interleukin-7, embryonic organ development, nucleotide-excision repair, prot...
Does Knockout of Asl in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Asl
protein/peptide distribution
myoblast cell line
Gene: Asl (argininosuccinate lyase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-amino acid metabolic process, L-arginine biosynthetic process, L-arginine biosynthetic process via ornithine, amino acid biosynthetic process, amino acid metabolic process, ammonia assim...
Does Knockout of Utp11 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Utp11
cell proliferation
Embryonic Stem Cell Line
Gene: Utp11 (UTP11 small subunit processome component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nervous system development, positive regulation of apoptotic process, rRNA processing, ribosomal small subunit biogenesis; CC: cytoplasm, cytosol, extracellular space, n...
Does Knockout of Map3k14 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Map3k14
cell proliferation
Mouse kidney carcinoma cell
Gene: Map3k14 (mitogen-activated protein kinase kinase kinase 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, cellular response to mechanical stimulus, defense response to virus, immune response, non-canonical NF-kappaB signal transduction; MF: ATP bindi...
Does Knockout of Zc3h12d in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Zc3h12d
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Zc3h12d (zinc finger CCCH type containing 12D) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 3'-UTR-mediated mRNA destabilization, mRNA catabolic process, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of T cell proliferation, ne...
Does Knockout of Pim2 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Pim2
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Pim2 (proviral integration site 2) Type: protein-coding Summary: Enables protein serine/threonine kinase activity. Involved in several processes, including positive regulation of canonical NF-kappaB signal transduction; positive regulation of metabolic process; and protein stabilization. Acts upst...
Does Knockout of Cc2d2a in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Cc2d2a
protein/peptide accumulation
Embryonic Cell Line
Gene: Cc2d2a (coiled-coil and C2 domain containing 2A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axoneme assembly, camera-type eye development, cell projection organization, cilium assembly, determination of left/right symmetry, embryonic brain development, heart de...
Does Knockout of Madd in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Madd
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Madd (MAP-kinase activating death domain) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterograde synaptic vesicle transport, apoptotic process, execution phase of apoptosis, negative regulation of apoptotic signaling pathway, negative regulation of growth hormo...
Does Knockout of Ctrb1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Ctrb1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ctrb1 (chymotrypsinogen B1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: digestion, positive regulation of apoptotic process, protein catabolic process, proteolysis, response to cytokine; MF: hydrolase activity, peptidase activity, serine-type endopeptidase activ...
Does Knockout of Adamts15 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Adamts15
cell proliferation
Mouse kidney carcinoma cell
Gene: Adamts15 (ADAM metallopeptidase with thrombospondin type 1 motif 15) Type: protein-coding Summary: This gene encodes a member of 'a disintegrin and metalloproteinase with thrombospondin motifs' (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissu...
Does Knockout of Mrpl45 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Mrpl45
cell proliferation
Embryonic Stem Cell Line
Gene: Mrpl45 (mitochondrial ribosomal protein L45) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, ribonucleoprotein ...
Does Knockout of Cdk5r1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Cdk5r1
cell proliferation
Mouse kidney carcinoma cell
Gene: Cdk5r1 (cyclin dependent kinase 5, regulatory subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled acetylcholine receptor signaling pathway, G1 to G0 transition involved in cell differentiation, axon guidance, axonal fasciculation, brain deve...
Does Knockout of Cd6 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Cd6
cell proliferation
Colonic Cancer Cell Line
Gene: Cd6 (CD6 antigen) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acute inflammatory response to antigenic stimulus, cell adhesion, heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, immunological synapse formation, lipopolysaccharide-media...
Does Knockout of Ddx3x in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ddx3x
cell proliferation
Embryonic Stem Cell Line
Gene: Ddx3x (DEAD box helicase 3, X-linked) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, apoptotic process, cell differentiation, cellular response to arsenic-containing substance, cellular response to osmotic stress, cellular response to virus, ...
Does Knockout of Rfx1 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Rfx1
cell cycle progression
breast epithelium
Gene: Rfx1 (regulatory factor X, 1 (influences HLA class II expression)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity...
Does Knockout of Cenph in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Cenph
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cenph (centromere protein H) Type: protein-coding Summary: Enables kinetochore binding activity. Predicted to be involved in chromosome segregation and mitotic spindle organization. Predicted to act upstream of or within mitotic cell cycle. Located in kinetochore and nucleus. Is expressed in sever...
Does Knockout of Urod in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Urod
protein/peptide distribution
myoblast cell line
Gene: Urod (uroporphyrinogen decarboxylase) Type: protein-coding Summary: This gene encodes an enzyme that catalyzes the conversion of uroporphyrinogen-III to coproporphyrinogen-III, an intermediate step in heme biosynthesis. Homozygous knockout mice for this gene exhibit embryonic lethality. [provided ...
Does Knockout of Kcne2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Kcne2
cell proliferation
Mouse kidney carcinoma cell
Gene: Kcne2 (potassium voltage-gated channel, Isk-related subfamily, gene 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cardiac muscle cell action potential involved in contraction, cellular response to xenobiotic stimulus, establishment of localization in cell, intr...
Does Knockout of Cox6c in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Cox6c
cell proliferation
Melanoma Cell Line
Gene: Cox6c (cytochrome c oxidase subunit 6C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, oxidative phosphorylation; CC: membrane, mitochondrial inner membrane, mitochondrial membrane, mitochondrion, respiratory chain complex IV Pathways: ...
Does Knockout of Chek2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Chek2
cell viability
Immortal mouse chromaffin cells
Gene: Chek2 (checkpoint kinase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage checkpoint signaling, DNA damage response, DNA damage response, signal transduction by p53 class mediator, DNA repair, G2/M transition of mitotic cell cycle, apoptotic process, au...
Does Knockout of Psg21 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Psg21
protein/peptide accumulation
Embryonic Cell Line
Gene: Psg21 (pregnancy-specific beta-1-glycoprotein 21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell activation, female pregnancy, immune response; CC: cellular_component, external side of plasma membrane Pathways: UniProt: S4R1D2, Q9DAV5 ...
Does Knockout of Usp20 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Usp20
cell proliferation
Embryonic Stem Cell Line
Gene: Usp20 (ubiquitin specific peptidase 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antiviral innate immune response, canonical NF-kappaB signal transduction, endocytosis, negative regulation of canonical NF-kappaB signal transduction, nervous system development...
Does Knockout of Sly in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Sly
cell viability
Immortal mouse chromaffin cells
Gene: Sly (Sycp3 like Y-linked) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A0A087WRK1, Q810R0, A0A9L6KDV5, A0A087WNQ6 Entrez ID: 382301
Does Knockout of Azin1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Azin1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Azin1 (antizyme inhibitor 1) Type: protein-coding Summary: The protein encoded by this gene belongs to the antizyme inhibitor family, which plays a role in cell growth and proliferation by maintaining polyamine homeostasis within the cell. Antizyme inhibitors are homologs of ornithine decarboxylas...
Does Knockout of Maea in bone marrow cell line causally result in regulation of signal transduction phenotype?
1
1,785
Knockout
Maea
regulation of signal transduction phenotype
bone marrow cell line
Gene: Maea (macrophage erythroblast attacher) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell division, cytoskeleton organization, enucleate erythrocyte development, erythrocyte development, erythrocyte maturation, negative regulation of myeloid cell a...
Does Knockout of Snip1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Snip1
cell proliferation
Embryonic Stem Cell Line
Gene: Snip1 (Smad nuclear interacting protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome, miRNA processing, negative regulation of canonical NF-kappaB signal transduction, positive regulation of transcr...
Does Knockout of Lepr in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Lepr
cell proliferation
Mouse kidney carcinoma cell
Gene: Lepr (leptin receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell differentiation, angiogenesis, bone growth, cell surface receptor signaling pathway via STAT, cholesterol metabolic process, cytokine-mediated signaling pathway, eating behavior, energy ho...
Does Knockout of Slc38a2 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Slc38a2
cell cycle progression
breast epithelium
Gene: Slc38a2 (solute carrier family 38, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-glutamine import across plasma membrane, L-proline import across plasma membrane, L-serine import across plasma membrane, L-serine transport, acidic amino acid transport, ...
Does Knockout of Tubb3 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Tubb3
protein/peptide distribution
myoblast cell line
Gene: Tubb3 (tubulin, beta 3 class III) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon guidance, dorsal root ganglion development, microtubule cytoskeleton organization, microtubule-based process, mitotic cell cycle, netrin-activated signaling pathway, neuron differ...
Does Knockout of Cbfb in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Cbfb
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cbfb (core binding factor beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell maturation, definitive hemopoiesis, lymphocyte differentiation, myeloid cell differentiation, negative regulation of CD4-positive, alpha-beta T cell differentiation, negative regula...
Does Knockout of Mkrn3 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Mkrn3
protein/peptide distribution
myoblast cell line
Gene: Mkrn3 (makorin, ring finger protein, 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein polyubiquitination, protein ubiquitination; MF: identical protein binding, metal ion binding, transferase activity, ubiquitin protein ligase activity, zinc ion binding ...
Does Knockout of Glrx3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Glrx3
cell proliferation
Mouse kidney carcinoma cell
Gene: Glrx3 (glutaredoxin 3) Type: protein-coding Summary: Predicted to enable identical protein binding activity and protein kinase C binding activity. Involved in negative regulation of cardiac muscle hypertrophy and regulation of the force of heart contraction. Located in Z disc. Is expressed in seve...
Does Knockout of Pcca in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Pcca
cell cycle progression
breast epithelium
Gene: Pcca (propionyl-Coenzyme A carboxylase, alpha polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid catabolic process, lipid metabolic process; MF: ATP binding, enzyme binding, ligase activity, metal ion binding, nucleotide binding, propionyl-CoA carbox...
Does Knockout of Ilvbl in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Ilvbl
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ilvbl (ilvB (bacterial acetolactate synthase)-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-valine biosynthetic process, fatty acid alpha-oxidation, fatty acid metabolic process, isoleucine biosynthetic process, lipid metabolic process; MF: acetolactate sy...
Does Knockout of Slc17a5 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Slc17a5
protein/peptide distribution
myoblast cell line
Gene: Slc17a5 (solute carrier family 17 (anion/sugar transporter), member 5) Type: protein-coding Summary: Enables D-glucuronate transmembrane transporter activity. Involved in neurotransmitter loading into synaptic vesicle. Acts upstream of or within response to bacterium. Located in cytoplasmic vesicl...
Does Knockout of Slc26a6 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Slc26a6
cell proliferation
Melanoma Cell Line
Gene: Slc26a6 (solute carrier family 26, member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiotensin-activated signaling pathway, bicarbonate transport, cellular response to cAMP, cellular response to fructose stimulus, cellular response to type II interferon, c...
Does Knockout of Tpst2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Tpst2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Tpst2 (protein-tyrosine sulfotransferase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fusion of sperm to egg plasma membrane involved in single fertilization, peptidyl-tyrosine sulfation, prevention of polyspermy; MF: protein homodimerization activity, protein...
Does Knockout of Ankrd13a in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Ankrd13a
cell proliferation
Embryonic Stem Cell Line
Gene: Ankrd13a (ankyrin repeat domain 13a) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of protein localization to endosome, negative regulation of receptor internalization; MF: ubiquitin-modified protein reader activity; CC: cytoplasm, endosome, la...
Does Knockout of Bcas2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Bcas2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Bcas2 (BCAS2 pre-mRNA processing factor) Type: protein-coding Summary: Acts upstream of or within several processes, including alternative mRNA splicing, via spliceosome; ovarian follicle development; and spindle assembly. Part of Prp19 complex. Is expressed in several structures, including centra...
Does Knockout of Ints10 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Ints10
cell cycle progression
breast epithelium
Gene: Ints10 (integrator complex subunit 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II transcription initiation surveillance, snRNA processing; CC: INTAC complex, integrator complex, nucleus Pathways: Gene expression (Transcription), RNA P...
Does Knockout of Col4a1 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Col4a1
protein/peptide distribution
Microglial Cell Line
Gene: Col4a1 (collagen, type IV, alpha 1) Type: protein-coding Summary: This gene encodes the alpha-1 subunit of the type IV collagens, an essential component of basement membranes. The encoded protein forms a triple helical heterotrimer comprised of two alpha-1 and one alpha-2 subunits that assembles i...
Does Knockout of Krtap13-1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Krtap13-1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Krtap13-1 (keratin associated protein 13-1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, cytosol, intermediate filament, keratin filament Pathways: Developmental Biology, Keratinization UniProt: Q8K198 Entrez ID: 2689...
Does Knockout of Rbm20 in Melanoma Cell Line causally result in cell proliferation?
1
2,492
Knockout
Rbm20
cell proliferation
Melanoma Cell Line
Gene: Rbm20 (RNA binding motif protein 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, heart formation, mRNA processing, negative regulation of mRNA splicing, via spliceosome, positive regulation of RNA splicing, regulation of RNA splicing, regulation of...
Does Knockout of Asf1a in Lung Cancer Cell Line causally result in tumorigenicity?
1
1,089
Knockout
Asf1a
tumorigenicity
Lung Cancer Cell Line
Gene: Asf1a (anti-silencing function 1A histone chaperone) Type: protein-coding Summary: Enables chromatin binding activity. Acts upstream of or within muscle cell differentiation and osteoblast differentiation. Predicted to be located in nucleoplasm. Predicted to be part of protein-containing complex. ...
Does Knockout of Padi6 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Padi6
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Padi6 (peptidyl arginine deiminase, type VI) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasm organization, cytoskeleton organization, embryonic cleavage, epigenetic programming in the zygotic pronuclei, in utero embryonic development, intracellular protein...
Does Knockout of Emc3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Emc3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Emc3 (ER membrane protein complex subunit 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein insertion into ER membrane by stop-transfer membrane-anchor sequence, tail-anchored membrane protein insertion into ER membrane; MF: membrane insertase activity; CC:...
Does Knockout of Rhox10 in Melanoma Cell Line causally result in cell proliferation?
1
2,492
Knockout
Rhox10
cell proliferation
Melanoma Cell Line
Gene: Rhox10 (reproductive homeobox 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: neuron development, positive regulation of gene expression, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase...
Does Knockout of Gjb5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Gjb5
cell proliferation
Mouse kidney carcinoma cell
Gene: Gjb5 (gap junction protein, beta 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell communication, cell-cell signaling, labyrinthine layer morphogenesis, spongiotrophoblast differentiation, transmembrane transport, trophoblast giant cell differentiation; CC: an...
Does Knockout of Coasy in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Coasy
protein/peptide distribution
myoblast cell line
Gene: Coasy (Coenzyme A synthase) Type: protein-coding Summary: This gene encodes the bifunctional protein coenzyme A (CoA) synthase which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this protein catal...
Does Knockout of Trpm4 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Trpm4
response to virus
Microglial Cell Line
Gene: Trpm4 (transient receptor potential cation channel, subfamily M, member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, calcium ion transmembrane transport, calcium ion transport, calcium-mediated signaling, cellular response to ATP, den...
Does Knockout of Gal3st1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Gal3st1
autophagy
Embryonic Fibroblast Cell Line
Gene: Gal3st1 (galactose-3-O-sulfotransferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: galactosylceramide biosynthetic process, galactosylceramide metabolic process, glycerolipid metabolic process, glycolipid biosynthetic process, lipid metabolic process, myelin...
Does Knockout of Pnma2 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Pnma2
response to virus
Embryonic Fibroblast Cell Line
Gene: Pnma2 (paraneoplastic antigen MA2) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, nucleolus, nucleus Pathways: UniProt: Q8BHK0 Entrez ID: 239157
Does Knockout of Cypt2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Cypt2
cell proliferation
Colonic Cancer Cell Line
Gene: Cypt2 (cysteine-rich perinuclear theca 2) Type: protein-coding Summary: cysteine-rich perinuclear theca 2 Gene Ontology: Pathways: UniProt: Q8CH23, Q6P924, A0A9L6KE70 Entrez ID: 245566
Does Knockout of Fabp3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Fabp3
cell proliferation
Mouse kidney carcinoma cell
Gene: Fabp3 (fatty acid binding protein 3, muscle and heart) Type: protein-coding Summary: Predicted to enable cytoskeletal protein binding activity; long-chain fatty acid binding activity; and long-chain fatty acid transmembrane transporter activity. Involved in several processes, including cholesterol...
Does Knockout of Cubn in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Cubn
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cubn (cubilin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cholesterol metabolic process, cobalamin catabolic process, cobalamin metabolic process, cobalamin transport, endocytic hemoglobin import into cell, establishment of localization in cell, in utero embryo...
Does Knockout of Clptm1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Clptm1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Clptm1 (cleft lip and palate associated transmembrane protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, regulation of T cell differentiation in thymus, regulation of postsynaptic membrane neurotransmitter receptor levels; MF: GABA rece...
Does Knockout of Wdr74 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Wdr74
cell cycle progression
breast epithelium
Gene: Wdr74 (WD repeat domain 74) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA metabolic process, blastocyst formation, rRNA processing, ribosomal large subunit biogenesis; CC: nuclear exosome (RNase complex), nucleolus, nucleoplasm, nucleus, preribosome, large sub...
Does Knockout of Ccnd3 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Ccnd3
cell proliferation
Melanoma Cell Line
Gene: Ccnd3 (cyclin D3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G1/S transition of mitotic cell cycle, T cell proliferation, cell division, hyaluronan biosynthetic process, negative regulation of transcription by RNA polymerase II, positive regulation of G1/S tran...
Does Knockout of Mroh1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Mroh1
autophagy
Embryonic Fibroblast Cell Line
Gene: Mroh1 (maestro heat-like repeat family member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, lysosome fission; MF: membrane destabilizing activity, molecular_function; CC: cytoplasm, lysosomal membrane, lysosome, membrane Pathways: ...
Does Knockout of Lrch2 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Lrch2
protein/peptide distribution
Microglial Cell Line
Gene: Lrch2 (leucine-rich repeats and calponin homology (CH) domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q3UMG5 Entrez ID: 210297
Does Knockout of Mlph in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Mlph
cell proliferation
Mouse kidney carcinoma cell
Gene: Mlph (melanophilin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular protein transport, melanocyte differentiation, melanosome localization, pigmentation, protein targeting; MF: actin binding, metal ion binding, microtubule plus-end binding, molecular a...
Does Knockout of Cntd1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Cntd1
cell proliferation
Mouse kidney carcinoma cell
Gene: Cntd1 (cyclin N-terminal domain containing 1) Type: protein-coding Summary: Involved in regulation of meiotic cell cycle. Acts upstream of or within reciprocal meiotic recombination and spermatogenesis. Located in chromosome. Orthologous to human CNTD1 (cyclin N-terminal domain containing 1). [pro...
Does Knockout of Gpnmb in Melanoma Cell Line causally result in cell proliferation?
1
2,492
Knockout
Gpnmb
cell proliferation
Melanoma Cell Line
Gene: Gpnmb (glycoprotein (transmembrane) nmb) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bone mineralization, cell adhesion, cell-cell signaling, negative regulation of G1/S transition of mitotic cell cycle, negative regulation of T cell activation, negative regulat...
Does Knockout of Gpr25 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Gpr25
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Gpr25 (G protein-coupled receptor 25) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, chemokine-mediated signaling pathway, leukocyte chemotaxis, lymphocyte chemotaxis, lymphocyte migration into lymphoid organs, signal t...
Does Knockout of Grm3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Grm3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Grm3 (glutamate receptor, metabotropic 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled glutamate receptor signaling pathway, G protein-coupled receptor signaling pathway, adenylate cyclase-inhibiting G protein-coupled glutamate receptor signalin...
Does Knockout of Ltb in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Ltb
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ltb (lymphotoxin B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway, gene expression, immune response, lymph node development, positive regulation of canonical NF-kappaB signal transduction, positive regulation of extrinsic ap...
Does Knockout of Dmd in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Dmd
protein/peptide distribution
myoblast cell line
Gene: Dmd (dystrophin, muscular dystrophy) Type: protein-coding Summary: This gene encodes a large, rod-like cytoskeletal protein which is found at the inner surface of muscle fibers in skeletal and cardiac muscles. The encoded protein, dystrophin, is part of the dystrophin-glycoprotein complex, which b...
Does Knockout of Smg7 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Smg7
response to virus
Embryonic Fibroblast Cell Line
Gene: Smg7 (SMG7 nonsense mediated mRNA decay factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; MF: protein phosphatase 2A binding, telomerase RNA binding, telomeric DNA binding; CC: cytoplasm, cyt...
Does Knockout of Tollip in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Tollip
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tollip (toll interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagy, epithelial cell differentiation, immune system process, inflammatory response, innate immune response, interleukin-1-mediated signaling pathway, phosphorylation, positive re...
Does Knockout of Prr15l in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Prr15l
cell proliferation
Embryonic Stem Cell Line
Gene: Prr15l (proline rich 15-like) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8JZM2 Entrez ID: 217138
Does Knockout of Msl3l2 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Msl3l2
response to virus
Embryonic Fibroblast Cell Line
Gene: Msl3l2 (MSL3 like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, regulation of DNA-templated transcription; MF: DNA binding, histone H4K16ac reader activity, histone reader activity; CC: MSL complex, NuA4 histone acetyltransferase complex...
Does Knockout of Dmpk in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Dmpk
cell proliferation
Embryonic Stem Cell Line
Gene: Dmpk (dystrophia myotonica-protein kinase) Type: protein-coding Summary: The protein encoded by this gene is a serine/threonine protein kinase that contains coiled-coil and C-terminal membrane association domains. In the embryonic mouse, it is found in cardiac and skeletal myocytes where it appear...
Does Knockout of Mir467e in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Mir467e
response to chemicals
Pancreatic Cancer Cell Line
Gene: Mir467e (microRNA 467e) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Sgpl1 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Sgpl1
response to virus
Embryonic Fibroblast Cell Line
Gene: Sgpl1 (sphingosine phosphate lyase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Leydig cell differentiation, androgen metabolic process, apoptotic process, apoptotic signaling pathway, carboxylic acid metabolic process, ceramide metabolic process, estrogen met...
Does Knockout of Ppm1h in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Ppm1h
cell proliferation
Colonic Cancer Cell Line
Gene: Ppm1h (protein phosphatase 1H (PP2C domain containing)) Type: protein-coding Summary: No summary available. Gene Ontology: MF: [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity, hydrolase activity, identical protein binding, phosphoprotein phosphatase activity, protein s...
Does Knockout of Mex3b in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Mex3b
protein/peptide accumulation
Mouse cell
Gene: Mex3b (mex3 RNA binding family member B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: establishment of localization in cell, positive regulation of cell-cell adhesion, positive regulation of phagocytosis, protein localization to cell cortex; MF: GTPase activating...
Does Knockout of Cyp4b1 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Cyp4b1
response to virus
Embryonic Fibroblast Cell Line
Gene: Cyp4b1 (cytochrome P450, family 4, subfamily b, polypeptide 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biphenyl metabolic process, fatty acid metabolic process; MF: heme binding, heterocyclic compound binding, iron ion binding, metal ion binding, monooxygena...
Does Knockout of Slco6c1 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Slco6c1
response to virus
Embryonic Fibroblast Cell Line
Gene: Slco6c1 (solute carrier organic anion transporter family, member 6c1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: organic anion transport, sodium-independent organic anion transport, transmembrane transport; MF: organic anion transmembrane transporter activity, ...
Does Knockout of Sec61b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Sec61b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sec61b (SEC61 translocon subunit beta) Type: protein-coding Summary: Enables ribosome binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, translocation; post-translational protein targeting to membrane, translocation; and retrograde protein tr...
Does Knockout of Ube2g2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,278
Knockout
Ube2g2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ube2g2 (ubiquitin-conjugating enzyme E2G 2) Type: protein-coding Summary: Enables identical protein binding activity and ubiquitin conjugating enzyme activity. Acts upstream of or within ERAD pathway. Located in cytosol and endoplasmic reticulum. Is expressed in several structures, including alime...
Does Knockout of Kat7 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Kat7
protein/peptide distribution
Microglial Cell Line
Gene: Kat7 (K(lysine) acetyltransferase 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, DNA replication-dependent chromatin disassembly, T cell differentiation, chromatin organization, internal peptidyl-lysine acetylati...