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Does Knockout of Mbtps1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Mbtps1
cell proliferation
Mouse kidney carcinoma cell
Gene: Mbtps1 (membrane-bound transcription factor peptidase, site 1) Type: protein-coding Summary: Enables serine-type endopeptidase activity. Involved in membrane protein intracellular domain proteolysis and mitotic G2 DNA damage checkpoint signaling. Acts upstream of or within lipid metabolic process....
Does Knockout of Ppy in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Ppy
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Ppy (pancreatic polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: feeding behavior, neuropeptide signaling pathway; MF: G protein-coupled receptor binding, hormone activity, neuropeptide Y receptor binding, neuropeptide hormone activity; CC: cytoplasm, ex...
Does Knockout of Rac1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Rac1
cell proliferation
Colonic Cancer Cell Line
Gene: Rac1 (Rac family small GTPase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, Rac protein signal transduction, Wnt signaling pathway, planar cell polarity pathway, actin cytoskeleton organization, actin filament organ...
Does Knockout of Serinc2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Serinc2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Serinc2 (serine incorporator 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: phosphatidylserine metabolic process, plasma membrane phospholipid scrambling; MF: acetyltransferase activator activity, phospholipid scramblase activity; CC: membrane, plasma membrane ...
Does Knockout of Sla2 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Sla2
cell proliferation
Embryonic Stem Cell Line
Gene: Sla2 (Src-like-adaptor 2) Type: protein-coding Summary: Predicted to enable signaling adaptor activity. Acts upstream of or within T cell activation. Located in late endosome and plasma membrane. Is expressed in thymus primordium. Orthologous to human SLA2 (Src like adaptor 2). [provided by Allian...
Does Knockout of Ndufaf6 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Ndufaf6
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ndufaf6 (NADH:ubiquinone oxidoreductase complex assembly factor 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial respiratory chain complex I assembly; CC: cytoplasm, membrane, mitochondrial inner membrane, mitochondrion, nucleus Pathways: Ae...
Does Knockout of Pmf1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Pmf1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pmf1 (polyamine-modulated factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: attachment of spindle microtubules to kinetochore, cell division, chromosome segregation, positive regulation of DNA-templated transcription; MF: leucine zipper domain binding, prote...
Does Knockout of Ubl5 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Ubl5
cell proliferation
Colonic Cancer Cell Line
Gene: Ubl5 (ubiquitin-like 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA splicing, via spliceosome, protein modification process; CC: cytoplasm, nucleus Pathways: Metabolism of RNA, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing, mRNA Sp...
Does Knockout of Mon2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Mon2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mon2 (MON2 homolog, regulator of endosome to Golgi trafficking) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to endosome transport, protein transport; CC: cytosol, early endosome membrane, endosome, membrane Pathways: UniProt: Q80TL7 ...
Does Knockout of Prrc1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Prrc1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Prrc1 (proline-rich coiled-coil 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: identical protein binding, protein kinase A regulatory subunit binding; CC: Golgi apparatus, cytoplasm Pathways: UniProt: Q3UPH1 Entrez ID: 73137
Does Knockout of Tango2 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Tango2
protein/peptide accumulation
Embryonic Cell Line
Gene: Tango2 (transport and golgi organization 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, protein secretion; CC: Golgi apparatus, cytoplasm, cytosol, mitochondrion Pathways: UniProt: P54797 Entrez ID: 27883
Does Knockout of Emc2 in Microglial Cell Line causally result in protein/peptide distribution?
1
1,585
Knockout
Emc2
protein/peptide distribution
Microglial Cell Line
Gene: Emc2 (ER membrane protein complex subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein insertion into ER membrane by stop-transfer membrane-anchor sequence, tail-anchored membrane protein insertion into ER membrane; MF: membrane insertase activity; CC:...
Does Knockout of Upf1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,172
Knockout
Upf1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Upf1 (UPF1 RNA helicase and ATPase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 3'-UTR-mediated mRNA destabilization, DNA repair, DNA replication, cell cycle phase transition, cellular response to interleukin-1, cellular response to lipopolysaccharide, histone m...
Does Knockout of Zfp563 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Zfp563
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfp563 (zinc finger protein 563) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II...
Does Knockout of Galnt10 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Galnt10
cell proliferation
Mouse kidney carcinoma cell
Gene: Galnt10 (polypeptide N-acetylgalactosaminyltransferase 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein O-linked glycosylation, protein O-linked glycosylation via N-acetyl-galactosamine, protein glycosylation; MF: carbohydrate binding, glycosyltransferase...
Does Knockout of Zfp955b in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Zfp955b
cell cycle progression
breast epithelium
Gene: Zfp955b (zinc finger protein 955B) Type: protein-coding Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcr...
Does Knockout of Pde6b in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Pde6b
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Pde6b (phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: detection of light stimulus, entrainment of circadian clock by photoperiod, negative regulation of cAMP/PKA signal transduction, retina development in ...
Does Knockout of Sharpin in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Sharpin
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sharpin (SHANK-associated RH domain interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic nuclear changes, defense response to bacterium, epidermis development, keratinization, mitochondrion organization, negative regulation of canonical NF-...
Does Knockout of Syt3 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Syt3
protein/peptide distribution
myoblast cell line
Gene: Syt3 (synaptotagmin III) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, chemical synaptic transmission, exocytosis, positive regulation of dendrite extension, positive regulation of vesicle fusion, regulation of calcium ion-dependent exocytosi...
Does Knockout of D630003M21Rik in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
D630003M21Rik
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: D630003M21Rik (RIKEN cDNA D630003M21 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8BWG4 Entrez ID: 228846
Does Knockout of Ehbp1 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Ehbp1
cell proliferation
Melanoma Cell Line
Gene: Ehbp1 (EH domain binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endocytosis, protein transport; CC: cytoplasm, cytosol, endosome, membrane, nucleoplasm, plasma membrane Pathways: UniProt: Q69ZW3 Entrez ID: 216565
Does Knockout of Adgrb2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Adgrb2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Adgrb2 (adhesion G protein-coupled receptor B2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, calcineurin-NFAT signaling cascade, cell surface receptor signaling pathway, negative regulation of angiogenesis, peripheral...
Does Knockout of Tomm6 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Tomm6
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tomm6 (translocase of outer mitochondrial membrane 6) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane, mitochondrial outer membrane, mitochondrial outer membrane translocase complex, mitochondrion Pathways: Autophagy, Macroautophagy, Mitophagy, PIN...
Does Knockout of Hmgb2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Hmgb2
cell proliferation
Embryonic Stem Cell Line
Gene: Hmgb2 (high mobility group box 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA recombination, DNA topological change, cell chemotaxis, cellular response to lipopolysaccharide, chemotaxis, chromatin remodeling, defense response to Gram-negative bacterium, defe...
Does Knockout of Guk1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Guk1
cell proliferation
Melanoma Cell Line
Gene: Guk1 (guanylate kinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GDP biosynthetic process, GDP metabolic process, GDP-mannose metabolic process, GMP metabolic process, dATP metabolic process, dGDP biosynthetic process, dGMP metabolic process, glycoprotein t...
Does Knockout of Eefsec in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Eefsec
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Eefsec (eukaryotic elongation factor, selenocysteine-tRNA-specific) Type: protein-coding Summary: Enables several functions, including GTP binding activity; RNA binding activity; and translation elongation factor activity. Acts upstream of or within selenocysteine incorporation. Located in mitocho...
Does Knockout of Timmdc1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Timmdc1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Timmdc1 (translocase of inner mitochondrial membrane domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, mitochondrial respiratory chain complex I assembly; CC: membrane, mitochondrial membrane, mitochondrion, nucleoplasm ...
Does Knockout of Rassf4 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Rassf4
protein/peptide accumulation
Embryonic Cell Line
Gene: Rassf4 (Ras association (RalGDS/AF-6) domain family member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: signal transduction Pathways: Hippo signaling pathway - multiple species - Mus musculus (mouse) UniProt: Q8CB96 Entrez ID: 213391
Does Knockout of Cfap69 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Cfap69
protein/peptide distribution
myoblast cell line
Gene: Cfap69 (cilia and flagella associated protein 69) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, flagellated sperm motility, olfactory behavior, positive regulation of fertilization, positive regulation of flagellated sperm motility, response ...
Does Knockout of Mrpl12 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Mrpl12
cell proliferation
Embryonic Stem Cell Line
Gene: Mrpl12 (mitochondrial ribosomal protein L12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial transcription, mitochondrial translation, positive regulation of DNA-templated transcription, translation; MF: mRNA binding, structural constituent of ribosome...
Does Knockout of Vmn1r148 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Vmn1r148
protein/peptide accumulation
Embryonic Cell Line
Gene: Vmn1r148 (vomeronasal 1 receptor 148) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled recepto...
Does Knockout of Akr1cl in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
1
1,522
Knockout
Akr1cl
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Akr1cl (aldo-keto reductase family 1, member C-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: daunorubicin metabolic process, doxorubicin metabolic process, progesterone metabolic process, prostaglandin metabolic process; MF: 15-hydroxyprostaglandin-D dehydro...
Does Knockout of Ces5a in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Ces5a
protein/peptide distribution
myoblast cell line
Gene: Ces5a (carboxylesterase 5A) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carboxylesterase activity, carboxylic ester hydrolase activity, hydrolase activity Pathways: UniProt: Q6AW46 Entrez ID: 67935
Does Knockout of Btbd9 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Btbd9
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Btbd9 (BTB domain containing 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adult locomotory behavior, circadian behavior, circadian sleep/wake cycle, non-REM sleep, long-term memory, modulation of chemical synaptic transmission, multicellular organismal-level i...
Does Knockout of Scgb1c1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Scgb1c1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Scgb1c1 (secretoglobin, family 1C, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, extracellular region Pathways: UniProt: G5E8B5 Entrez ID: 338417
Does Knockout of Fen1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Fen1
cell proliferation
Embryonic Stem Cell Line
Gene: Fen1 (flap structure specific endonuclease 1) Type: protein-coding Summary: Enables DNA binding activity; metal ion binding activity; and nuclease activity. Acts upstream of or within DNA repair and DNA replication. Predicted to be located in mitochondrion; nucleolus; and nucleoplasm. Predicted to...
Does Knockout of Prex2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Prex2
cell proliferation
Mouse kidney carcinoma cell
Gene: Prex2 (phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2) Type: protein-coding Summary: Predicted to enable GTPase activator activity; guanyl-nucleotide exchange factor activity; and protein serine/threonine kinase inhibitor activity. Acts upstream of or within adult locomot...
Does Knockout of Atp6v1g1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Atp6v1g1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Atp6v1g1 (ATPase, H+ transporting, lysosomal V1 subunit G1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to increased oxygen levels, intracellular iron ion homeostasis, monoatomic ion transport, proton transmembrane transport, synaptic vesicle l...
Does Knockout of Hirip3 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Hirip3
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Hirip3 (HIRA interacting protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, chromatin organization; MF: H2A-H2B histone complex chaperone activity, molecular_function; CC: nucleolus, nucleoplasm, nucleus Pathways: UniPr...
Does Knockout of Mars2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Mars2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Mars2 (methionine-tRNA synthetase 2 (mitochondrial)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: methionyl-tRNA aminoacylation, tRNA aminoacylation for protein translation, translation; MF: ATP binding, aminoacyl-tRNA ligase activity, ligase activity, methionine...
Does Knockout of Fap in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Fap
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Fap (fibroblast activation protein) Type: protein-coding Summary: This gene belongs to the serine protease family. The encoded protein is an inducible cell-surface bound glycoprotein specifically expressed in tumor-associated fibroblasts and pericytes of epithelial tumors and has protease and gela...
Does Knockout of Cops8 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Cops8
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Cops8 (COP9 signalosome subunit 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: COP9 signalosome assembly, negative regulation of cell population proliferation, protein deneddylation; CC: COP9 signalosome, cytoplasm, cytosol, nucleoplasm, nucleus, perinuclear reg...
Does Knockout of Ndufs3 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Ndufs3
cell proliferation
Embryonic Stem Cell Line
Gene: Ndufs3 (NADH:ubiquinone oxidoreductase core subunit S3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, mitochondrial electron transport, NADH to ubiquinone, mitochondrial respiratory chain complex I assembly, proton motive force-driven mitochon...
Does Knockout of Ankrd52 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Ankrd52
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ankrd52 (ankyrin repeat domain 52) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8BTI7 Entrez ID: 237615
Does Knockout of Ywhae in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Ywhae
protein/peptide distribution
myoblast cell line
Gene: Ywhae (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to plasma membrane transport, MAPK cascade, cellular response to heat, cerebral cortex development, cytoplasmic ...
Does Knockout of Vmn1r223 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Vmn1r223
protein/peptide distribution
myoblast cell line
Gene: Vmn1r223 (vomeronasal 1 receptor 223) Type: protein-coding Summary: vomeronasal 1 receptor 223 Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled re...
Does Knockout of Hibadh in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Hibadh
protein/peptide distribution
myoblast cell line
Gene: Hibadh (3-hydroxyisobutyrate dehydrogenase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-valine catabolic process, branched-chain amino acid catabolic process; MF: 3-hydroxyisobutyrate dehydrogenase activity, NAD binding, NADP binding, oxidoreductase activity; ...
Does Knockout of Wfdc6b in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Wfdc6b
cell proliferation
Mouse kidney carcinoma cell
Gene: Wfdc6b (WAP four-disulfide core domain 6B) Type: protein-coding Summary: No summary available. Gene Ontology: MF: molecular_function, peptidase inhibitor activity, serine-type endopeptidase inhibitor activity; CC: extracellular region, extracellular space Pathways: UniP...
Does Knockout of Ncapg2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Ncapg2
cell proliferation
Mouse kidney carcinoma cell
Gene: Ncapg2 (non-SMC condensin II complex, subunit G2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, chromatin organization, chromosome condensation, erythrocyte differentiation, inner cell mass cell proliferation, mitotic sister chromatid segregation, p...
Does Knockout of Tifa in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Tifa
protein/peptide accumulation
Embryonic Cell Line
Gene: Tifa (TRAF-interacting protein with forkhead-associated domain) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic pattern recognition receptor signaling pathway, immune system process, innate immune response, positive regulation of canonical NF-kappaB sign...
Does Knockout of Rbms3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Rbms3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rbms3 (RNA binding motif, single stranded interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to tumor cell, negative regulation of canonical Wnt signaling pathway, negative regulation of gene expression, positive regulation of gene...
Does Knockout of Cops7b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Cops7b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cops7b (COP9 signalosome subunit 7B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: COP9 signalosome assembly, protein deneddylation; CC: COP9 signalosome, cytoplasm, nucleoplasm, nucleus Pathways: Cargo recognition for clathrin-mediated endocytosis, Clath...
Does Knockout of Nelfa in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Nelfa
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Nelfa (negative elongation factor complex member A, Whsc2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription elongation by RNA polymerase II, positive regulation of transcription by RNA polymerase II; MF: chromatin binding, molecul...
Does Knockout of Tmem44 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Tmem44
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tmem44 (transmembrane protein 44) Type: protein-coding Summary: No summary available. Gene Ontology: BP: basic amino acid transmembrane transport, biological_process; MF: basic amino acid transmembrane transporter activity, molecular_function Pathways: UniProt: Q8C820, ...
Does Knockout of Gbp10 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Gbp10
cell proliferation
Colonic Cancer Cell Line
Gene: Gbp10 (guanylate-binding protein 10) Type: protein-coding Summary: Predicted to enable GTP binding activity and GTPase activity. Acts upstream of or within cellular response to lipopolysaccharide and defense response to other organism. Located in cytoplasmic vesicle. Is expressed in several struct...
Does Knockout of Chmp4b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Chmp4b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Chmp4b (charged multivesicular body protein 4B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome maturation, autophagy, exit from mitosis, late endosome to lysosome transport, late endosome to vacuole transport via multivesicular body sorting pathway, m...
Does Knockout of Nr2f1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Nr2f1
cell proliferation
Mouse kidney carcinoma cell
Gene: Nr2f1 (nuclear receptor subfamily 2, group F, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cerebral cortex regionalization, forebrain development, interneuron migration, intracellular receptor signaling pathway, negative regulation...
Does Knockout of Mybbp1a in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Mybbp1a
cell proliferation
Embryonic Stem Cell Line
Gene: Mybbp1a (MYB binding protein (P160) 1a) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to glucose starvation, chromatin remodeling, circadian regulation of gene expression, intrinsic apoptotic signaling pathway by p53 class mediator, negative regu...
Does Knockout of Wars2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Wars2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Wars2 (tryptophanyl tRNA synthetase 2 (mitochondrial)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial tryptophanyl-tRNA aminoacylation, positive regulation of angiogenesis, tRNA aminoacylation for protein translation, translation, tryptophanyl-tRNA am...
Does Knockout of Ndufv2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Ndufv2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ndufv2 (NADH:ubiquinone oxidoreductase core subunit V2) Type: protein-coding Summary: This gene encodes a subunit of the NADH-ubiquinone oxidoreductase (complex I) enzyme, which is a large, multimeric protein. It is the first enzyme complex in the mitochondrial electron transport chain and catalyz...
Does Knockout of Pax2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Pax2
cell proliferation
Mouse kidney carcinoma cell
Gene: Pax2 (paired box 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain morphogenesis, branching involved in ureteric bud morphogenesis, camera-type eye development, cell differentiation, cell fate determination, cellular response to glucose stimulus, cellular res...
Does Knockout of Med31 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Med31
cell proliferation
Colonic Cancer Cell Line
Gene: Med31 (mediator complex subunit 31) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, limb development, negative regulation of fibroblast proliferation, positive regulation of transcription elongation by RNA polymerase...
Does Knockout of P2ry4 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
P2ry4
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: P2ry4 (pyrimidinergic receptor P2Y, G-protein coupled, 4) Type: protein-coding Summary: Enables G protein-coupled UTP receptor activity. Acts upstream of or within cellular response to prostaglandin E stimulus and transepithelial chloride transport. Predicted to be located in apical plasma membran...
Does Knockout of Dnm1l in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Dnm1l
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Dnm1l (dynamin 1-like) Type: protein-coding Summary: This gene encodes a member of the dynamin family. The encoded protein is localized to the cytoplasm and mitochondrial membrane, is involved in mitochondrial and peroxisomal division, and is essential for mitochondrial fission. Alternative splici...
Does Knockout of Xrcc5 in Lymphoma Cell Line causally result in response to chemicals?
1
1,536
Knockout
Xrcc5
response to chemicals
Lymphoma Cell Line
Gene: Xrcc5 (X-ray repair complementing defective repair in Chinese hamster cells 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, activation of innate immune response, cellular hyperosmotic salinity response, cellular...
Does Knockout of Mettl1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Mettl1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mettl1 (methyltransferase 1, tRNA methylguanosine) Type: protein-coding Summary: Predicted to enable internal mRNA (guanine-N7-)-methyltransferase activity and tRNA (guanine(46)-N7)-methyltransferase activity. Predicted to be involved in tRNA (guanine-N7)-methylation and tRNA stabilization. Predic...
Does Knockout of Psg17 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Psg17
cell cycle progression
breast epithelium
Gene: Psg17 (pregnancy specific beta-1-glycoprotein 17) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell activation, female pregnancy, immune response; MF: heparan sulfate proteoglycan binding, protein binding Pathways: UniProt: Q62056 Ent...
Does Knockout of Dpagt1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Dpagt1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Dpagt1 (dolichyl-phosphate N-acetylglucosaminephosphotransferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: dolichol-linked oligosaccharide biosynthetic process, protein N-linked glycosylation, protein glycosylation; MF: UDP-N-acetylglucosamine-dolichyl-phos...
Does Knockout of Vars2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Vars2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Vars2 (valyl-tRNA synthetase 2, mitochondrial) Type: protein-coding Summary: Predicted to enable valine-tRNA ligase activity. Predicted to be involved in valyl-tRNA aminoacylation. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; inte...
Does Knockout of Raver1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Raver1
cell proliferation
Mouse kidney carcinoma cell
Gene: Raver1 (ribonucleoprotein, PTB-binding 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: RNA binding, nucleic acid binding; CC: cytoplasm, nucleus Pathways: UniProt: Q9CW46 Entrez ID: 71766
Does Knockout of Polq in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Polq
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Polq (polymerase (DNA directed), theta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, DNA-templated DNA replication, base-excision repair, double-strand break repair, double-strand break repair via alternative nonh...
Does Knockout of Ppp4c in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Ppp4c
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ppp4c (protein phosphatase 4, catalytic subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: double-strand break repair via homologous recombination, regulation of double-strand break repair, regulation of double-strand break repair via homologous recombination;...
Does Activation of Camta1 in Mouse cell causally result in protein/peptide accumulation?
1
690
Activation
Camta1
protein/peptide accumulation
Mouse cell
Gene: Camta1 (calmodulin binding transcription activator 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: neuromuscular process controlling balance, positive regulation of calcineurin-NFAT signaling cascade, positive regulation of transcription by RNA polymerase II, reg...
Does Knockout of Hnf1b in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Hnf1b
cell proliferation
Melanoma Cell Line
Gene: Hnf1b (HNF1 homeobox B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, anterior/posterior pattern specification, blastocyst development, branching morphogenesis of an epithelial tube, circadian regulation of gene expression, embryonic diges...
Does Knockout of Gprin2 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Gprin2
response to chemicals
Pancreatic Cancer Cell Line
Gene: Gprin2 (G protein regulated inducer of neurite outgrowth 2) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: D3Z1D7, A0A2I3BRN2, A0A2I3BQP8 Entrez ID: 432839
Does Knockout of Seh1l in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Seh1l
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Seh1l (SEH1-like (S. cerevisiae) Type: protein-coding Summary: No summary available. Gene Ontology: BP: attachment of mitotic spindle microtubules to kinetochore, cell division, cellular response to amino acid starvation, cellular response to nutrient levels, chromosome segregation, defen...
Does Knockout of Ankrd34a in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Ankrd34a
cell cycle progression
breast epithelium
Gene: Ankrd34a (ankyrin repeat domain 34A) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q7TST1, B2RW11 Entrez ID: 545554
Does Knockout of Dync2li1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Dync2li1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Dync2li1 (dynein cytoplasmic 2 light intermediate chain 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, cilium assembly, determination of left/right symmetry, intraciliary retrograde transport, intraciliary transport involved in cili...
Does Knockout of S100a6 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
S100a6
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: S100a6 (S100 calcium binding protein A6 (calcyclin)) Type: protein-coding Summary: No summary available. Gene Ontology: MF: S100 protein binding, calcium ion binding, calcium-dependent protein binding, metal ion binding, monoatomic ion transmembrane transporter activity, protein binding, ...
Does Knockout of Eif1ad in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Eif1ad
cell proliferation
Embryonic Stem Cell Line
Gene: Eif1ad (eukaryotic translation initiation factor 1A domain containing) Type: protein-coding Summary: No summary available. Gene Ontology: MF: RNA binding, translation initiation factor activity; CC: cytosol, nucleoplasm, nucleus Pathways: UniProt: Q3THJ3 Entrez ...
Does Knockout of Slc38a2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Slc38a2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Slc38a2 (solute carrier family 38, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-glutamine import across plasma membrane, L-proline import across plasma membrane, L-serine import across plasma membrane, L-serine transport, acidic amino acid transport, ...
Does Knockout of St6galnac5 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
St6galnac5
protein/peptide distribution
myoblast cell line
Gene: St6galnac5 (ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ganglioside biosynthetic process, glycosphingolipid biosynthetic process, lipid metabolic proce...
Does Knockout of Spg7 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Spg7
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Spg7 (SPG7, paraplegin matrix AAA peptidase subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterograde axonal transport, calcium import into the mitochondrion, cell adhesion, mitochondrial outer membrane permeabilization involved in programmed cell death, ...
Does Knockout of Fbxw4 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Fbxw4
cell proliferation
Melanoma Cell Line
Gene: Fbxw4 (F-box and WD-40 domain protein 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, Wnt signaling pathway, cartilage development, embryonic digit morphogenesis, limb development, positive ...
Does Knockout of Cyb5d1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Cyb5d1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Cyb5d1 (cytochrome b5 domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, cilium movement, regulation of cilium beat frequency; MF: metal ion binding, molecular_function; CC: cell projection, cellular_component, cytoplasm, cytosk...
Does Knockout of Prpf40a in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Prpf40a
cell proliferation
Embryonic Stem Cell Line
Gene: Prpf40a (pre-mRNA processing factor 40A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, cell migration, cytoskeleton organization, mRNA cis splicing, via spliceosome, mRNA processing, mRNA splicing, via spliceosome, regulation of cell shape, regulatio...
Does Knockout of Ebf2 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Ebf2
protein/peptide distribution
myoblast cell line
Gene: Ebf2 (early B cell factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adipose tissue development, brown fat cell differentiation, cell fate determination, positive regulation of DNA-templated transcription, positive regulation of cold-induced thermogenesis, p...
Does Knockout of Gin1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Gin1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gin1 (gypsy retrotransposon integrase 1) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8K259 Entrez ID: 252876
Does Knockout of Dhx38 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Dhx38
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Dhx38 (DEAH-box helicase 38) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome; MF: 3'-5' RNA helicase activity, ATP binding, ATP-dependent activity, acting on RNA, RNA binding, RNA helicase activity, helic...
Does Knockout of Arhgef5 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,440
Knockout
Arhgef5
protein/peptide accumulation
Embryonic Cell Line
Gene: Arhgef5 (Rho guanine nucleotide exchange factor 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, hematopoietic stem cell homeostasis, intracellular signal transduction, myeloid dendritic cell chemotaxis, positive regulation of podo...
Does Knockout of Gtpbp3 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Gtpbp3
protein/peptide distribution
myoblast cell line
Gene: Gtpbp3 (GTP binding protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial tRNA wobble uridine modification, tRNA methylation, tRNA modification, tRNA processing, tRNA wobble uridine modification; MF: GTP binding, GTPase activity, hydrolase activit...
Does Knockout of Irgm1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Irgm1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Irgm1 (immunity-related GTPase family M member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CAMKK-AMPK signaling cascade, NLRP3 inflammasome complex assembly, antibacterial innate immune response, autophagosome assembly, autophagosome maturation, autophagy, ce...
Does Knockout of Acsl5 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Acsl5
cell proliferation
Melanoma Cell Line
Gene: Acsl5 (acyl-CoA synthetase long-chain family member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid metabolic process, fatty acid transport, lipid metabolic process, long-chain fatty acid metabolic process, long-chain fatty-acyl-CoA biosynthetic proces...
Does Knockout of Dnajc11 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Dnajc11
cell proliferation
Mouse kidney carcinoma cell
Gene: Dnajc11 (DnaJ heat shock protein family (Hsp40) member C11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cristae formation; CC: MICOS complex, SAM complex, membrane, mitochondrial inner membrane, mitochondrial outer membrane, mitochondrion, nuclear speck, nucleop...
Does Knockout of Hbs1l in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Hbs1l
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Hbs1l (Hbs1-like (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of gene expression, nuclear-transcribed mRNA catabolic process, no-go decay, regulation of translation, rescue of stalled ribosome, ribosome disassembly, translatio...
Does Knockout of Thsd7b in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Thsd7b
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Thsd7b (thrombospondin, type I, domain containing 7B) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane, plasma membrane Pathways: Metabolism of proteins, O-glycosylation of TSR domain-containing proteins, O-linked glycosylation, Post-translational p...
Does Knockout of Rpl23a in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Rpl23a
cell proliferation
Melanoma Cell Line
Gene: Rpl23a (ribosomal protein L23A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, TORC2 complex binding, large ribosomal subunit rRNA binding, protein binding...
Does Knockout of Rhox4c in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Rhox4c
protein/peptide distribution
myoblast cell line
Gene: Rhox4c (reproductive homeobox 4C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription activator ac...
Does Knockout of Trib3 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Trib3
cell proliferation
Mouse kidney carcinoma cell
Gene: Trib3 (tribbles pseudokinase 3) Type: protein-coding Summary: Enables enzyme binding activity; transcription corepressor activity; and ubiquitin-protein transferase regulator activity. Involved in several processes, including cellular response to insulin stimulus; negative regulation of fat cell d...
Does Knockout of B3galt2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
B3galt2
cell proliferation
Colonic Cancer Cell Line
Gene: B3galt2 (UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: galactosylceramide biosynthetic process, lipid metabolic process, oligosaccharide biosynthetic process, protein O-linked glycosylation, protein...