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Does Knockout of Srpx2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Srpx2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Srpx2 (sushi-repeat-containing protein, X-linked 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, cell adhesion, cell motility, cell-cell adhesion, positive regulation of cell migration involved in sprouting angiogenesis, positive regulation of synap...
Does Knockout of Mrps34 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Mrps34
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Mrps34 (mitochondrial ribosomal protein S34) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondrion, ribonucleoprotein ...
Does Knockout of Slc22a13 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Slc22a13
cell proliferation
Melanoma Cell Line
Gene: Slc22a13 (solute carrier family 22 (organic cation transporter), member 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of fatty acid metabolic process, nicotinate transport, positive regulation of T cell mediated cytotoxicity directed agains...
Does Knockout of Hba-a1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Hba-a1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Hba-a1 (hemoglobin alpha, adult chain 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbon dioxide transport, erythrocyte development, in utero embryonic development, nitric oxide transport, oxygen transport, response to bacterium, response to stilbenoid; MF: G...
Does Knockout of Hdac10 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Hdac10
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Hdac10 (histone deacetylase 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, autophagy, homologous recombination, macroautophagy, negative regulation of DNA-templated transcription, negative regulation of transc...
Does Knockout of Wasf1 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Wasf1
response to virus
Embryonic Fibroblast Cell Line
Gene: Wasf1 (WASP family, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rac protein signal transduction, actin cytoskeleton organization, cellular response to brain-derived neurotrophic factor stimulus, dendrite extension, dendritic transport of mitochondrion,...
Does Knockout of Sh3bp1 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Sh3bp1
response to virus
Embryonic Fibroblast Cell Line
Gene: Sh3bp1 (SH3-domain binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament organization, cell junction assembly, cell migration, establishment of epithelial cell apical/basal polarity, filopodium assembly, negative regulation of small GTPas...
Does Knockout of Zfp488 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Zfp488
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfp488 (zinc finger protein 488) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, nervous system development, oligodendrocyte development, positive regulation of myelination, positive regulation of oligodendrocyte d...
Does Knockout of Rell2 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Rell2
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Rell2 (RELT-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of cell-substrate adhesion, positive regulation of p38MAPK cascade; CC: basement membrane, extracellular matrix, membrane, plasma membrane Pathways: UniProt: Q...
Does Knockout of Glt1d1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Glt1d1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Glt1d1 (glycosyltransferase 1 domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: glycosyltransferase activity, molecular_function, transferase activity; CC: cytosol, extracellular region Pathways: UniProt: A4FUP9 Entrez I...
Does Knockout of Strap in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Strap
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Strap (serine/threonine kinase receptor associated protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, alternative mRNA splicing, via spliceosome, mRNA processing, mRNA splicing, via spliceosome, maintenance of gastrointestinal epithelium, negativ...
Does Knockout of Coa7 in Microglial Cell Line causally result in response to virus?
1
2,429
Knockout
Coa7
response to virus
Microglial Cell Line
Gene: Coa7 (cytochrome c oxidase assembly factor 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, respiratory chain complex IV assembly; MF: molecular_function, protein-disulfide reductase activity; CC: mitochondrial intermembrane space, mitochondrio...
Does Knockout of Bicra in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Bicra
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Bicra (BRD4 interacting chromatin remodeling complex associated protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin remodeling, negative regulation of cell differentiation, positive regulation of DNA-templated transcription, positive regulation of cel...
Does Knockout of Slc38a7 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Slc38a7
protein/peptide accumulation
Regulatory T cell
Gene: Slc38a7 (solute carrier family 38, member 7) Type: protein-coding Summary: Enables L-glutamine:sodium symporter activity. Involved in glutamine transport and sodium ion transport. Located in axon and neuronal cell body. Is expressed in several structures, including alimentary system; central nervo...
Does Knockout of Neurog3 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Neurog3
protein/peptide distribution
myoblast cell line
Gene: Neurog3 (neurogenin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon development, cell differentiation, developmental process, enteroendocrine cell differentiation, epithelial cell differentiation, forebrain development, hindbrain development, negative regula...
Does Knockout of Psmc6 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Psmc6
cell proliferation
Embryonic Stem Cell Line
Gene: Psmc6 (proteasome (prosome, macropain) 26S subunit, ATPase, 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, positive regulation of RNA polymerase II transcription preinitiation complex assembly, positive regulation of inclusion body assembly, protea...
Does Knockout of St13 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
St13
protein/peptide accumulation
Embryonic Cell Line
Gene: St13 (suppression of tumorigenicity 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein folding, response to bacterium; MF: Hsp70 protein binding, dATP binding, identical protein binding, protein dimerization activity, protein domain specific binding, protei...
Does Knockout of Serf2 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Serf2
cell proliferation
Embryonic Stem Cell Line
Gene: Serf2 (small EDRK-rich factor 2) Type: protein-coding Summary: Predicted to be involved in protein destabilization. Predicted to be located in cytosol and nucleus. Is expressed in several structures, including brain; endocrine gland; genitourinary system; oral epithelium; and respiratory system. O...
Does Knockout of Atg14 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Atg14
response to virus
Embryonic Fibroblast Cell Line
Gene: Atg14 (autophagy related 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, autophagosome maturation, autophagosome membrane docking, autophagy, cellular response to glucose starvation, cellular response to starvation, defense response to vi...
Does Knockout of Zcchc18 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Zcchc18
protein/peptide distribution
myoblast cell line
Gene: Zcchc18 (zinc finger, CCHC domain containing 18) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, zinc ion binding Pathways: UniProt: Q8VD24 Entrez ID: 66995
Does Knockout of Tbl3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Tbl3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tbl3 (transducin (beta)-like 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rR...
Does Knockout of Krt9 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Krt9
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Krt9 (keratin 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: epithelial cell differentiation, intermediate filament organization, morphogenesis of an epithelium, skin development, spermatogenesis; MF: structural constituent of skin epidermis, structural molecule...
Does Knockout of Sptlc1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Sptlc1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Sptlc1 (serine palmitoyltransferase, long chain base subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ceramide biosynthetic process, lipid metabolic process, positive regulation of lipophagy, regulation of fat cell apoptotic process, sphinganine biosynthet...
Does Knockout of Oacyl in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Oacyl
protein/peptide distribution
myoblast cell line
Gene: Oacyl (O-acyltransferase like) Type: protein-coding Summary: No summary available. Gene Ontology: MF: acyltransferase activity, transferring groups other than amino-acyl groups, molecular_function; CC: cellular_component, membrane Pathways: UniProt: Q8BML2 Entre...
Does Knockout of Dapk1 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Dapk1
protein/peptide accumulation
Mouse cell
Gene: Dapk1 (death associated protein kinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, apoptotic signaling pathway, cellular response to hydroperoxide, cellular response to type II interferon, defense response to tumor cell, extrinsic apoptotic...
Does Knockout of Tspyl3 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Tspyl3
cell proliferation
Embryonic Stem Cell Line
Gene: Tspyl3 (TSPY-like 3) Type: protein-coding Summary: Predicted to enable chromatin binding activity and histone binding activity. Predicted to be active in chromatin and nucleus. Orthologous to human TSPY26P (testis specific protein Y-linked 26, pseudogene). [provided by Alliance of Genome Resources...
Does Knockout of Tor1aip1 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Tor1aip1
cell viability
Immortal mouse chromaffin cells
Gene: Tor1aip1 (torsin A interacting protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nuclear membrane organization, positive regulation of ATP-dependent activity, protein localization to nuclear envelope; MF: ATPase activator activity, ATPase binding, cytoskele...
Does Knockout of Tas2r113 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Tas2r113
protein/peptide accumulation
Mouse cell
Gene: Tas2r113 (taste receptor, type 2, member 113) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of bitter taste, detection of chemical stimulus involved in sens...
Does Knockout of Mir6239 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Mir6239
response to chemicals
Pancreatic Cancer Cell Line
Gene: Mir6239 (microRNA 6239) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Rpl13 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Rpl13
cell proliferation
Melanoma Cell Line
Gene: Rpl13 (ribosomal protein L13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blastocyst development, bone development, cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, structural constituent of ribosome; ...
Does Knockout of Gatad2a in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Gatad2a
cell proliferation
Mouse kidney carcinoma cell
Gene: Gatad2a (GATA zinc finger domain containing 2A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterior neuropore closure, blood vessel development, chromatin remodeling, embryonic body morphogenesis, in utero embryonic development, negative regulation of DNA-templ...
Does Knockout of Ablim1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ablim1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ablim1 (actin-binding LIM protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon guidance, cilium assembly, cytoskeleton organization, lamellipodium assembly, positive regulation of transcription by RNA polymerase II, transcription by RNA polymerase II; MF:...
Does Knockout of Wbp2nl in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Wbp2nl
cell cycle progression
breast epithelium
Gene: Wbp2nl (WBP2 N-terminal like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: egg activation, female pronucleus assembly, male pronucleus assembly, positive regulation of DNA-templated transcription; MF: WW domain binding, chromatin DNA binding, transcription coacti...
Does Knockout of Ifnar1 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Ifnar1
protein/peptide distribution
myoblast cell line
Gene: Ifnar1 (interferon (alpha and beta) receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell activation, cell surface receptor signaling pathway via JAK-STAT, cellular response to interferon-alpha, cellular response to interferon-beta, cytokine-mediated si...
Does Knockout of U2af1l4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
U2af1l4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: U2af1l4 (U2 small nuclear RNA auxiliary factor 1-like 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome, rhythmic process; MF: RNA binding, metal ion binding, nucleic acid binding, pre-mRNA 3'-splice sit...
Does Knockout of Drd2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Drd2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Drd2 (dopamine receptor D2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled dopamine receptor signaling pathway, G protein-coupled receptor internalization, G protein-coupled receptor signaling pathway, Wnt signaling pathway, acid secretion, adenoh...
Does Knockout of Zfp981 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Zfp981
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Zfp981 (zinc finger protein 981) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II...
Does Knockout of Eif2s3y in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Eif2s3y
cell proliferation
Mouse kidney carcinoma cell
Gene: Eif2s3y (eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked) Type: protein-coding Summary: Predicted to enable translation initiation factor activity. Predicted to contribute to tRNA binding activity. Acts upstream of or within positive regulation of male gonad develop...
Does Knockout of Ddx28 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Ddx28
autophagy
Embryonic Fibroblast Cell Line
Gene: Ddx28 (DEAD box helicase 28) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial large ribosomal subunit assembly, ribosome biogenesis; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase activity, hydrolase activity, nuc...
Does Knockout of Itgb3bp in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Itgb3bp
cell viability
Immortal mouse chromaffin cells
Gene: Itgb3bp (integrin beta 3 binding protein (beta3-endonexin)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CENP-A containing chromatin assembly, apoptotic process, cell division, chromosome segregation, negative regulation of epithelial cell apoptotic process, posi...
Does Knockout of Ubr4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ubr4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ubr4 (ubiquitin protein ligase E3 component n-recognin 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: HRI-mediated signaling, cellular response to stress, cytoplasm protein quality control, cytoplasm protein quality control by the ubiquitin-proteasome system, en...
Does Knockout of Ivd in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
0
2,474
Knockout
Ivd
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Ivd (isovaleryl coenzyme A dehydrogenase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-leucine catabolic process, branched-chain amino acid catabolic process, fatty acid beta-oxidation using acyl-CoA dehydrogenase; MF: 3-methylbutanoyl-CoA dehydrogenase activit...
Does Knockout of Tyk2 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Tyk2
protein/peptide distribution
myoblast cell line
Gene: Tyk2 (tyrosine kinase 2) Type: protein-coding Summary: Predicted to enable growth hormone receptor binding activity; non-membrane spanning protein tyrosine kinase activity; and type 1 angiotensin receptor binding activity. Involved in cell population proliferation and positive regulation of T cell...
Does Knockout of Egln1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Egln1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Egln1 (egl-9 family hypoxia-inducible factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cardiac muscle tissue morphogenesis, cellular response to hypoxia, heart trabecula formation, intracellular iron ion homeostasis, intracellular oxygen homeostasis, labyri...
Does Knockout of Rfng in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Rfng
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Rfng (RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase) Type: protein-coding Summary: Enables O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity. Involved in regulation of Notch signaling pathway. Acts upstream of or within positive regulation of Notch signaling pathway. ...
Does Knockout of Map7d1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Map7d1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Map7d1 (MAP7 domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule cytoskeleton organization; CC: centrosome, cytoplasm, cytoskeleton, microtubule cytoskeleton, midbody, spindle Pathways: UniProt: A2AJI0 Entrez I...
Does Knockout of Prkdc in Lymphoma Cell Line causally result in response to chemicals?
1
1,528
Knockout
Prkdc
response to chemicals
Lymphoma Cell Line
Gene: Prkdc (protein kinase, DNA activated, catalytic polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell lineage commitment, DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, T cell differentiation in thymus, T cell lineage commi...
Does Knockout of Glud1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Glud1
protein/peptide distribution
myoblast cell line
Gene: Glud1 (glutamate dehydrogenase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-glutamate catabolic process, amino acid metabolic process, glutamine metabolic process, positive regulation of insulin secretion, response to aluminum ion, tricarboxylic acid metabol...
Does Knockout of Adamts9 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Adamts9
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Adamts9 (ADAM metallopeptidase with thrombospondin type 1 motif 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: camera-type eye morphogenesis, cornea development in camera-type eye, extracellular matrix organization, lens development in camera-type eye, positive ...
Does Knockout of Zfp532 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Zfp532
protein/peptide distribution
myoblast cell line
Gene: Zfp532 (zinc finger protein 532) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, metal ion binding, molecular_function, zinc ion binding Pathways: UniProt: Q6NXK2 Entrez ID: 328977
Does Knockout of Coa4 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Coa4
cell proliferation
Melanoma Cell Line
Gene: Coa4 (cytochrome c oxidase assembly factor 4) Type: protein-coding Summary: No summary available. Gene Ontology: CC: mitochondrial intermembrane space, mitochondrion Pathways: Thermogenesis - Mus musculus (mouse) UniProt: Q8BT51 Entrez ID: 68185
Does Knockout of Nxf1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Nxf1
cell proliferation
Melanoma Cell Line
Gene: Nxf1 (nuclear RNA export factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA export from nucleus, mRNA export from nucleus, mRNA transport, poly(A)+ mRNA export from nucleus, protein transport; MF: RNA binding, mRNA binding, nucleic acid binding, protein b...
Does Knockout of Tapbp in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Tapbp
cell viability
Immortal mouse chromaffin cells
Gene: Tapbp (TAP binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MHC class Ib protein complex assembly, antigen processing and presentation of endogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via...
Does Knockout of B3gnt7 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
B3gnt7
protein/peptide accumulation
Mouse cell
Gene: B3gnt7 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: keratan sulfate proteoglycan biosynthetic process, poly-N-acetyllactosamine biosynthetic process, protein O-linked glycosylation, protein glycosyla...
Does Knockout of Tmem132e in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Tmem132e
cell proliferation
Regulatory T cell
Gene: Tmem132e (transmembrane protein 132E) Type: protein-coding Summary: Predicted to be involved in posterior lateral line neuromast hair cell development. Located in cell body. Is expressed in nervous system. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 99. O...
Does Knockout of Zdbf2 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Zdbf2
protein/peptide accumulation
Regulatory T cell
Gene: Zdbf2 (zinc finger, DBF-type containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: epigenetic programming of gene expression, genomic imprinting Pathways: UniProt: Q5SS00 Entrez ID: 73884
Does Knockout of Map3k21 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Map3k21
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Map3k21 (mitogen-activated protein kinase kinase kinase 21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, signal transduction; MF: ATP binding, JUN kinase kinase kinase activity, MAP kinase kinase kinase activity, kinase activity, nucleotide binding,...
Does Knockout of Cybb in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Cybb
cell proliferation
Mouse kidney carcinoma cell
Gene: Cybb (cytochrome b-245, beta polypeptide) Type: protein-coding Summary: This gene encodes the heavy chain component of a heterodimeric transmembrane ion transporter composed of both a heavy and a light chain. This transporter mediates the transfer of electrons from nicotinamide adenine dinucleotid...
Does Knockout of Ces2d-ps in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Ces2d-ps
cell proliferation
Colonic Cancer Cell Line
Gene: Ces2d-ps (carboxylesterase 2D, pseudogene) Type: pseudo Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 667754
Does Knockout of Esco2 in Lymphoma Cell Line causally result in response to chemicals?
1
1,558
Knockout
Esco2
response to chemicals
Lymphoma Cell Line
Gene: Esco2 (establishment of sister chromatid cohesion N-acetyltransferase 2) Type: protein-coding Summary: Enables L-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor. Acts upstream of or within several processes, including double-strand break repair; hematopoietic progenitor ce...
Does Knockout of Adh1 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Adh1
protein/peptide distribution
myoblast cell line
Gene: Adh1 (alcohol dehydrogenase 1 (class I)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ regeneration, behavioral response to ethanol, ethanol catabolic process, lipid metabolic process, response to ethanol, response to progesterone, response to retinoi...
Does Knockout of F11 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
F11
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: F11 (coagulation factor XI) Type: protein-coding Summary: This gene encodes a glycoprotein coagulation factor that plays an important role in intrinsic pathway of blood coagulation and hemostasis. The encoded protein is an inactive zymogen that can be activated by coagulation factor XIIa, thrombin...
Does Knockout of Apoo in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Apoo
response to chemicals
Pancreatic Cancer Cell Line
Gene: Apoo (apolipoprotein O) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cristae formation; CC: Golgi apparatus, Golgi membrane, MICOS complex, cytosol, endoplasmic reticulum, endoplasmic reticulum membrane, extracellular region, membrane, mitochondrial inner membran...
Does Knockout of Tgfbrap1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Tgfbrap1
protein/peptide distribution
myoblast cell line
Gene: Tgfbrap1 (transforming growth factor, beta receptor associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagy, endosomal vesicle fusion, endosome to lysosome transport, intracellular protein transport, protein transport, regulation of DNA-templ...
Does Knockout of Rps2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Rps2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Rps2 (ribosomal protein S2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to interleukin-4, cytoplasmic translation, translation; MF: RNA binding, enzyme binding, fibroblast growth factor binding, mRNA binding, protein-containing complex binding,...
Does Knockout of Col28a1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Col28a1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Col28a1 (collagen, type XXVIII, alpha 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: extracellular matrix structural constituent conferring tensile strength, peptidase inhibitor activity, serine-type endopeptidase inhibitor activity; CC: basement membrane, colla...
Does Knockout of Rock1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Rock1
cell proliferation
Mouse kidney carcinoma cell
Gene: Rock1 (Rho-associated coiled-coil containing protein kinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rho protein signal transduction, actin cytoskeleton organization, actomyosin structure organization, apical constriction, apoptotic process, bleb assembly,...
Does Knockout of Gata5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Gata5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gata5 (GATA binding protein 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aortic valve morphogenesis, cardiac jelly development, cardiac muscle tissue development, cell fate commitment, cellular response to BMP stimulus, cellular response to hydrogen peroxide, ...
Does Knockout of Rps23 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Rps23
protein/peptide distribution
myoblast cell line
Gene: Rps23 (ribosomal protein S23) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, maintenance of translational fidelity, ribosomal small subunit biogenesis, stress granule assembly, translation; MF: protein binding, structural constituent of rib...
Does Knockout of Rpl13a-ps1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Rpl13a-ps1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Rpl13a-ps1 (ribosomal protein 13A, pseudogene 1) Type: pseudo Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 433251
Does Knockout of Aatf in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Aatf
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Aatf (apoptosis antagonizing transcription factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, embryonic cleavage, negative regulation of amyloid precursor protein biosynthetic process, negative regulation of apoptotic process, negative regulation...
Does Knockout of Tnks1bp1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Tnks1bp1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Tnks1bp1 (tankyrase 1 binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to ionizing radiation, double-strand break repair; MF: ankyrin repeat binding, enzyme binding, protein serine/threonine kinase activator activity, protein-cont...
Does Knockout of Nap1l3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Nap1l3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nap1l3 (nucleosome assembly protein 1-like 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nucleosome assembly; MF: chromatin binding, histone binding; CC: chromatin, cytoplasm, nucleus Pathways: UniProt: Q794H2 Entrez ID: 54561
Does Knockout of Rpl4 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Rpl4
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Rpl4 (ribosomal protein L4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: 5S rRNA binding, RNA binding, protein binding, structural constituent of ribosome; CC: A band...
Does Knockout of Lrp12 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Lrp12
protein/peptide accumulation
Embryonic Cell Line
Gene: Lrp12 (low density lipoprotein-related protein 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell migration, endocytosis, integrin activation, lymphocyte migration into lymphoid organs, neuron migration, neuron projection development; MF: integr...
Does Knockout of Hnrnpul1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Hnrnpul1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Hnrnpul1 (heterogeneous nuclear ribonucleoprotein U-like 1) Type: protein-coding Summary: Predicted to enable RNA binding activity and enzyme binding activity. Predicted to be involved in alternative mRNA splicing, via spliceosome. Is active in synapse. Orthologous to human HNRNPUL1 (heterogeneous...
Does Knockout of Itm2c in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Itm2c
protein/peptide accumulation
Mouse cell
Gene: Itm2c (integral membrane protein 2C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of amyloid precursor protein biosynthetic process, negative regulation of neuron projection development, neuron differentiation, positive regulation of extrinsic...
Does Knockout of Hk1 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Hk1
cell proliferation
Melanoma Cell Line
Gene: Hk1 (hexokinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GDP-mannose biosynthetic process from mannose, canonical glycolysis, carbohydrate metabolic process, carbohydrate phosphorylation, establishment of protein localization to mitochondrion, fructose 6-p...
Does Knockout of Gm10604 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Gm10604
cell proliferation
Colonic Cancer Cell Line
Gene: Gm10604 (predicted gene 10604) Type: unknown Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 100038424
Does Knockout of Defa23 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Defa23
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Defa23 (defensin, alpha, 23) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, defense response, defense response to Gram-negative bacterium, defense response to G...
Does Knockout of Map3k7 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Map3k7
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Map3k7 (mitogen-activated protein kinase kinase kinase 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: I-kappaB phosphorylation, JNK cascade, MAPK cascade, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, angiogenesis, anoikis, apoptotic p...
Does Knockout of Slitrk3 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Slitrk3
cell cycle progression
breast epithelium
Gene: Slitrk3 (SLIT and NTRK-like family, member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axonogenesis, gephyrin clustering involved in postsynaptic density assembly, neurotransmitter-gated ion channel clustering, positive regulation of synapse assembly, postsyn...
Does Knockout of Mtpap in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Mtpap
cell proliferation
Embryonic Stem Cell Line
Gene: Mtpap (mitochondrial poly(A) polymerase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA 3'-end processing, RNA metabolic process, histone mRNA catabolic process, mRNA processing, mitochondrial RNA 3'-end processing, mitochondrial mRNA polyadenylation; MF: ATP b...
Does Knockout of Zfp532 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Zfp532
cell proliferation
Melanoma Cell Line
Gene: Zfp532 (zinc finger protein 532) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, metal ion binding, molecular_function, zinc ion binding Pathways: UniProt: Q6NXK2 Entrez ID: 328977
Does Knockout of Satl1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Satl1
cell proliferation
Colonic Cancer Cell Line
Gene: Satl1 (spermidine/spermine N1-acetyl transferase-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: polyamine metabolic process, spermidine acetylation; MF: acyltransferase activity, acyltransferase activity, transferring groups other than amino-acyl groups, di...
Does Knockout of Fancf in Lymphoma Cell Line causally result in response to chemicals?
1
1,536
Knockout
Fancf
response to chemicals
Lymphoma Cell Line
Gene: Fancf (Fanconi anemia, complementation group F) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, interstrand cross-link repair, ovarian follicle development, protein ubiquitination, spermatogenesis; CC: Fanconi anaemia nuclear complex...
Does Knockout of Msi1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Msi1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Msi1 (musashi RNA-binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: central nervous system development, epithelial cell differentiation, regulation of translation, response to hormone; MF: RNA binding, identical protein binding, mRNA binding, molecu...
Does Knockout of Hes5 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Hes5
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Hes5 (hes family bHLH transcription factor 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, S-shaped body morphogenesis, animal organ development, anterior/posterior pattern specification, astrocyte differentiation, brain development, came...
Does Knockout of Ppp3ca in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Ppp3ca
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ppp3ca (protein phosphatase 3, catalytic subunit, alpha isoform) Type: protein-coding Summary: Enables calmodulin binding activity and calmodulin-dependent protein phosphatase activity. Involved in several processes, including positive regulation of cell differentiation; positive regulation of tra...
Does Knockout of Rbfox3 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Rbfox3
protein/peptide distribution
Microglial Cell Line
Gene: Rbfox3 (RNA binding protein, fox-1 homolog (C. elegans) 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, nervous system development, regulation of RNA splicing, regulation of alternative mRNA splicing, via spliceosome; MF: DNA bindin...
Does Knockout of 3100002H09Rik in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
3100002H09Rik
cell proliferation
Mouse kidney carcinoma cell
Gene: 3100002H09Rik (RIKEN cDNA 3100002H09 gene) Type: ncRNA Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 70249
Does Knockout of Exoc5 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Exoc5
cell proliferation
Embryonic Stem Cell Line
Gene: Exoc5 (exocyst complex component 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to plasma membrane transport, epithelial cell apoptotic process, establishment of planar polarity, exocytosis, homeostasis of number of cells within a tissue, membrane fission,...
Does Knockout of Rbm43 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Rbm43
cell proliferation
Mouse kidney carcinoma cell
Gene: Rbm43 (RNA binding motif protein 43) Type: protein-coding Summary: No summary available. Gene Ontology: MF: RNA binding, molecular_function, nucleic acid binding Pathways: UniProt: Q99J64 Entrez ID: 71684
Does Knockout of Vmn1r71 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Vmn1r71
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Vmn1r71 (vomeronasal 1 receptor 71) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor ...
Does Knockout of Cnot10 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Cnot10
response to virus
Embryonic Fibroblast Cell Line
Gene: Cnot10 (CCR4-NOT transcription complex, subunit 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA catabolic process, negative regulation of translation, regulation of translation, regulatory ncRNA-mediated gene silencing; CC: CCR4-NOT complex, cytoplasm, cyto...
Does Knockout of Atm in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Atm
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Atm (ataxia telangiectasia mutated) Type: protein-coding Summary: Enables histone H2AXS139 kinase activity. Involved in several processes, including cellular response to retinoic acid; negative regulation of TORC1 signaling; and regulation of macromolecule biosynthetic process. Acts upstream of or...
Does Knockout of Sdhc in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Sdhc
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sdhc (succinate dehydrogenase complex, subunit C, integral membrane protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial electron transport, succinate to ubiquinone, proton motive force-driven mitochondrial ATP synthesis, tricarboxylic acid cycle; ...
Does Knockout of Ap2s1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Ap2s1
protein/peptide distribution
myoblast cell line
Gene: Ap2s1 (adaptor-related protein complex 2, sigma 1 subunit) Type: protein-coding Summary: Predicted to enable clathrin adaptor activity. Predicted to be involved in postsynaptic neurotransmitter receptor internalization and synaptic vesicle endocytosis. Part of AP-2 adaptor complex. Is active in sy...
Does Knockout of Mrpl38 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Mrpl38
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mrpl38 (mitochondrial ribosomal protein L38) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytosol, mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrial ribosome, mitochondrion, ribonucleoprotein complex, ribosome Pathways: M...
Does Knockout of Ngb in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Ngb
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ngb (neuroglobin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to hydrogen peroxide, cellular response to hypoxia, negative regulation of apoptotic process, neuron projection development, oxygen transport, response to hypoxia; MF: GDP-dissociati...