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Does Knockout of Zfp383 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Zfp383
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfp383 (zinc finger protein 383) Type: protein-coding Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcrip...
Does Knockout of Capn6 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Capn6
cell viability
Immortal mouse chromaffin cells
Gene: Capn6 (calpain 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule bundle formation, proteolysis, regulation of cytoskeleton organization; MF: calcium-dependent cysteine-type endopeptidase activity, microtubule binding, protein binding; CC: cytoplasm, cyt...
Does Knockout of Uimc1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Uimc1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Uimc1 (ubiquitin interaction motif containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, chromatin organization, double-strand break repair, mitotic G2 DNA damage checkpoint signalin...
Does Knockout of Lsm1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Lsm1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Lsm1 (LSM1 homolog, mRNA degradation associated) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, deadenylation-dependent decapping of nuclear-transcribed mRNA, histone mRNA catabolic process, mRNA processing, negative regulation of neuron differentiati...
Does Knockout of Llgl1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Llgl1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Llgl1 (LLGL1 scribble cell polarity complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to plasma membrane transport, axonogenesis, brain development, cortical actin cytoskeleton organization, establishment of spindle orientation, exocytosis, ma...
Does Knockout of Atf6b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Atf6b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Atf6b (activating transcription factor 6 beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endoplasmic reticulum unfolded protein response, mitotic chromosome condensation, negative regulation of ATF6-mediated unfolded protein response, negative regulation of ge...
Does Knockout of Wdr82 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Wdr82
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Wdr82 (WD repeat domain containing 82) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription termination, RNA polymerase II promoter clearance, gene expression, lncRNA catabolic process, negative regulation of DNA-templated transcription, elong...
Does Knockout of Anxa3 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Anxa3
response to virus
Microglial Cell Line
Gene: Anxa3 (annexin A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to bacterium, neutrophil degranulation, phagocytosis, positive regulation of DNA metabolic process, positive regulation of angiogenesis, positive regulation of endothelial cell migra...
Does Knockout of Washc1 in macrophage causally result in phagocytosis?
1
1,888
Knockout
Washc1
phagocytosis
macrophage
Gene: Washc1 (WASH complex subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Arp2/3 complex-mediated actin nucleation, T cell proliferation, dendritic cell antigen processing and presentation, endocytic recycling, endosomal transport, endosome organization, endos...
Does Knockout of Ikbkg in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,271
Knockout
Ikbkg
cell proliferation
Mouse kidney carcinoma cell
Gene: Ikbkg (inhibitor of kappaB kinase gamma) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell homeostasis, DNA damage response, anoikis, canonical NF-kappaB signal transduction, defense response to bacterium, establishment of vesicle localization, negative regulat...
Does Knockout of Hmgb3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Hmgb3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Hmgb3 (high mobility group box 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA geometric change, immune system process, innate immune response, negative regulation of B cell differentiation, negative regulation of myeloid cell differentiation; MF: DNA binding...
Does Knockout of Rps27 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Rps27
cell proliferation
Embryonic Stem Cell Line
Gene: Rps27 (ribosomal protein S27) Type: protein-coding Summary: No summary available. Gene Ontology: BP: rRNA processing, ribosomal small subunit assembly, ribosomal small subunit biogenesis, translation, translation at postsynapse, translation at presynapse; MF: RNA binding, metal ion bindin...
Does Knockout of Enpp5 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Enpp5
protein/peptide distribution
Microglial Cell Line
Gene: Enpp5 (ectonucleotide pyrophosphatase/phosphodiesterase 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell communication, nucleotide catabolic process; MF: NAD+ diphosphatase activity, dinucleotide phosphatase activity, hydrolase activity, metal ion binding, zi...
Does Knockout of Plk3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Plk3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Plk3 (polo like kinase 3) Type: protein-coding Summary: This gene encodes a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal catalytic domain and a carboxy-terminal bipartite polo box domain that funct...
Does Knockout of Hdac3 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Hdac3
cell proliferation
Mouse kidney carcinoma cell
Gene: Hdac3 (histone deacetylase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair-dependent chromatin remodeling, cellular response to fluid shear stress, cellular response to mechanical stimulus, cellular response to parathyroid hormone stimulus, chromatin o...
Does Knockout of Nek2 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Nek2
protein/peptide distribution
myoblast cell line
Gene: Nek2 (NIMA (never in mitosis gene a)-related expressed kinase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blastocyst development, cell division, centrosome separation, chromosome segregation, meiotic cell cycle, mitotic cell cycle, mitotic sister chromatid se...
Does Knockout of Bphl in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Bphl
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Bphl (biphenyl hydrolase like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: homocysteine metabolic process, xenobiotic metabolic process; MF: alpha-amino-acid esterase activity, hydrolase activity, metal ion binding, serine hydrolase activity; CC: mitochondrion ...
Does Knockout of Utp11 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Utp11
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Utp11 (UTP11 small subunit processome component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nervous system development, positive regulation of apoptotic process, rRNA processing, ribosomal small subunit biogenesis; CC: cytoplasm, cytosol, extracellular space, n...
Does Knockout of Dbt in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Dbt
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Dbt (dihydrolipoamide branched chain transacylase E2) Type: protein-coding Summary: Predicted to enable acetyltransferase activity; lipoic acid binding activity; and ubiquitin protein ligase binding activity. Predicted to contribute to branched-chain alpha-keto acid dehydrogenase activity. Predict...
Does Knockout of Apol7b in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Apol7b
protein/peptide distribution
myoblast cell line
Gene: Apol7b (apolipoprotein L 7b) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid transport, lipoprotein metabolic process; MF: chloride channel activity, lipid binding; CC: extracellular region, extracellular space, high-density lipoprotein particle, very-low-dens...
Does Knockout of Larp4 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Larp4
cell proliferation
Embryonic Stem Cell Line
Gene: Larp4 (La ribonucleoprotein 4) Type: protein-coding Summary: Predicted to enable mRNA 3'-UTR binding activity and poly(A) binding activity. Predicted to be involved in cytoskeleton organization; positive regulation of translation; and regulation of cell morphogenesis. Predicted to be part of cytos...
Does Knockout of Mrgpra3 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Mrgpra3
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Mrgpra3 (MAS-related GPR, member A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, acute-phase response, cell surface receptor signaling pathway, chemosensory behavior, response to chloroquine, signal transduction; MF:...
Does Knockout of Atp13a2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Atp13a2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Atp13a2 (ATPase type 13A2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome organization, autophagosome-lysosome fusion, autophagy, cellular response to manganese ion, cellular response to oxidative stress, extracellular exosome biogenesis, intracellula...
Does Knockout of Gsdmcl1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Gsdmcl1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gsdmcl1 (gasdermin C-like 1) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Snu13 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Snu13
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Snu13 (SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, box C/D snoRNP assembly, mRNA processing, mRNA splicing, via spliceosome, maturation of SSU-rRNA, ribosomal small subunit biogenesis, ribo...
Does Knockout of Polr2m in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Polr2m
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Polr2m (polymerase (RNA) II (DNA directed) polypeptide M) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maintenance of ER location, transcription elongation by RNA polymerase II; MF: RNA polymerase II complex binding, molecular_function, transcription elongation f...
Does Knockout of Mettl16 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Mettl16
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mettl16 (methyltransferase 16, N6-methyladenosine) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA methylation, RNA modification, S-adenosylmethionine biosynthetic process, mRNA catabolic process, mRNA destabilization, mRNA processing, methylation, negative regu...
Does Knockout of Ubc in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Ubc
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ubc (ubiquitin C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: modification-dependent protein catabolic process, protein ubiquitination; MF: protein binding, protein tag activity, ubiquitin protein ligase binding; CC: cytoplasm, cytosol, membrane, mitochondrial o...
Does Knockout of Elmod1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Elmod1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Elmod1 (ELMO/CED-12 domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cilium assembly, intracellular protein localization, protein transport; MF: GTPase activator activity; CC: Golgi apparatus, cilium, glutamatergic synapse, synapse Pathw...
Does Knockout of Ccnd1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,172
Knockout
Ccnd1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Ccnd1 (cyclin D1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, G1/S transition of mitotic cell cycle, Leydig cell differentiation, Wnt signaling pathway, animal organ regeneration, cell division, cell population proliferation, cellular respon...
Does Knockout of Dda1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Dda1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Dda1 (DET1 and DDB1 associated 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein polyubiquitination, protein ubiquitination, regulation of proteasomal ubiquitin-dependent prot...
Does Knockout of Sf3a1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Sf3a1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sf3a1 (splicing factor 3a, subunit 1) Type: protein-coding Summary: Predicted to enable RNA binding activity. Predicted to be involved in U2-type prespliceosome assembly. Predicted to be located in nuclear speck. Predicted to be part of U2 snRNP and spliceosomal complex. Is expressed in central ne...
Does Knockout of Sart3 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Sart3
response to virus
Embryonic Fibroblast Cell Line
Gene: Sart3 (squamous cell carcinoma antigen recognized by T cells 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA processing, RNA splicing, cell morphogenesis, hematopoietic stem cell proliferation, homeostasis of number of cells, mRNA processing, mRNA splicing, v...
Does Knockout of Zfp119a in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Zfp119a
protein/peptide distribution
myoblast cell line
Gene: Zfp119a (zinc finger protein 119a) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RN...
Does Knockout of Zfp157 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Zfp157
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfp157 (zinc finger protein 157) Type: protein-coding Summary: No summary available. Gene Ontology: BP: epithelial cell fate commitment, lung alveolus development, mammary gland morphogenesis, regulation of DNA-templated transcription, regulation of cell fate commitment, regulation of tra...
Does Knockout of Lrfn2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Lrfn2
cell proliferation
Mouse kidney carcinoma cell
Gene: Lrfn2 (leucine rich repeat and fibronectin type III domain containing 2) Type: protein-coding Summary: Involved in modulation of chemical synaptic transmission and regulation of postsynapse organization. Located in cell surface. Is active in Schaffer collateral - CA1 synapse; postsynapse; and pres...
Does Knockout of Ndufa2 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Ndufa2
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Ndufa2 (NADH:ubiquinone oxidoreductase subunit A2) Type: protein-coding Summary: This gene encodes a subunit of the NADH-ubiquinone oxidoreductase (complex I) enzyme, which is a large, multimeric protein. It is the first enzyme complex in the mitochondrial electron transport chain and catalyzes th...
Does Knockout of Krtap7-1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Krtap7-1
protein/peptide accumulation
Regulatory T cell
Gene: Krtap7-1 (keratin associated protein 7-1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, intermediate filament Pathways: UniProt: Q9D3I6 Entrez ID: 71363
Does Knockout of Ercc4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ercc4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ercc4 (excision repair cross-complementing rodent repair deficiency, complementation group 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, UV protection, cellular response to UV, double-strand break repair via homologous recombina...
Does Knockout of Mocs3 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Mocs3
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Mocs3 (molybdenum cofactor synthesis 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Mo-molybdopterin cofactor biosynthetic process, molybdopterin cofactor biosynthetic process, protein urmylation, tRNA processing, tRNA thio-modification, tRNA wobble position uri...
Does Knockout of Hjurp in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Hjurp
cell proliferation
Melanoma Cell Line
Gene: Hjurp (Holliday junction recognition protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CENP-A containing chromatin assembly, chromosome segregation, regulation of protein-containing complex assembly; MF: DNA binding, histone binding, identical protein binding...
Does Knockout of Toe1 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Toe1
response to virus
Microglial Cell Line
Gene: Toe1 (target of EGR1, member 1 (nuclear)) Type: protein-coding Summary: Predicted to enable poly(A)-specific ribonuclease activity and snRNA binding activity. Predicted to be involved in snRNA 3'-end processing. Predicted to be located in cytoplasm and nuclear body. Predicted to be active in Cajal...
Does Knockout of Rprd1b in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Rprd1b
protein/peptide distribution
myoblast cell line
Gene: Rprd1b (regulation of nuclear pre-mRNA domain containing 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II promoter clearance, mRNA 3'-end processing, positive regulation of cell population proliferation, positive regulation of transcription by R...
Does Knockout of Rufy3 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Rufy3
protein/peptide accumulation
Embryonic Cell Line
Gene: Rufy3 (RUN and FYVE domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament organization, cell differentiation, negative regulation of axonogenesis, nervous system development, positive regulation of axon extension, positive regulation of...
Does Knockout of Nckap1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Nckap1
protein/peptide accumulation
Embryonic Cell Line
Gene: Nckap1 (NCK-associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rac protein signal transduction, apical protein localization, basal protein localization, cell migration, cell migration involved in gastrulation, cell morphogenesis, cell projection a...
Does Knockout of Med26 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Med26
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Med26 (mediator complex subunit 26) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, positive regulation of gene expression, positive regulation of transcription elongation by RNA polymerase II, positive regulation of...
Does Knockout of Sod1 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Sod1
phagocytosis
macrophage
Gene: Sod1 (superoxide dismutase 1, soluble) Type: protein-coding Summary: No summary available. Gene Ontology: BP: action potential initiation, anterograde axonal transport, auditory receptor cell stereocilium organization, cellular response to ATP, cellular response to cadmium ion, cellular r...
Does Knockout of Tat in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Tat
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Tat (tyrosine aminotransferase) Type: protein-coding Summary: This gene encodes a liver-specific mitochondrial enzyme that catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Regulated by glucocorticoid and polypeptide hormones, this gene's expression is affected by deletion of a ...
Does Knockout of Snapc5 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Snapc5
protein/peptide accumulation
Embryonic Cell Line
Gene: Snapc5 (small nuclear RNA activating complex, polypeptide 5) Type: protein-coding Summary: Predicted to enable RNA polymerase II general transcription initiation factor activity and RNA polymerase III general transcription initiation factor activity. Predicted to be involved in snRNA transcription...
Does Knockout of Edc3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Edc3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Edc3 (enhancer of mRNA decapping 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: P-body assembly, deadenylation-independent decapping of nuclear-transcribed mRNA; MF: RNA binding, identical protein binding, mRNA binding; CC: P-body, cytoplasm, cytoplasmic ribonuc...
Does Knockout of Retn in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Retn
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Retn (resistin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fat cell differentiation, negative regulation of feeding behavior, positive regulation of collagen metabolic process, positive regulation of progesterone secretion, positive regulation of smooth muscle ...
Does Knockout of Rps10 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Rps10
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Rps10 (ribosomal protein S10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, ribosomal small subunit assembly, translation at postsynapse, translation at presynapse; MF: RNA binding, structural constituent of ribosome, tRNA binding; CC: cyt...
Does Knockout of Sbno1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,172
Knockout
Sbno1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Sbno1 (strawberry notch 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, inflammatory response, negative regulation of MAPK cascade, negative regulation of canonical NF-kappaB signal transduction, negative regulation of neuroinflammatory res...
Does Knockout of Scml2 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Scml2
protein/peptide distribution
myoblast cell line
Gene: Scml2 (Scm polycomb group protein like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, intracellular protein localization, negative regulation of DNA-templated transcription, protein localization to chromosome, regulation of DNA-templated trans...
Does Knockout of Ctnnbip1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Ctnnbip1
cell proliferation
Mouse kidney carcinoma cell
Gene: Ctnnbip1 (catenin beta interacting protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, anterior/posterior pattern specification, branching involved in ureteric bud morphogenesis, canonical Wnt signaling pathway, negative regulation of W...
Does Knockout of Wdhd1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Wdhd1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Wdhd1 (WD repeat and HMG-box DNA binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair, DNA-templated DNA replication, RNA processing, mitotic cell cycle, pericentric heterochromatin organization, regulation of chromosome organization; MF: DN...
Does Knockout of Laptm4b in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Laptm4b
cell proliferation
Mouse kidney carcinoma cell
Gene: Laptm4b (lysosomal-associated protein transmembrane 4B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endosome organization, endosome transport via multivesicular body sorting pathway, negative regulation of lysosomal protein catabolic process, negative regulation...
Does Knockout of Rab4a in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
1
1,522
Knockout
Rab4a
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Rab4a (RAB4A, member RAS oncogene family) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rab protein signal transduction, antigen processing and presentation, neurotransmitter receptor transport postsynaptic membrane to endosome, protein transport, regulation of en...
Does Knockout of Ddx51 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Ddx51
protein/peptide distribution
Microglial Cell Line
Gene: Ddx51 (DEAD box helicase 51) Type: protein-coding Summary: No summary available. Gene Ontology: BP: rRNA processing, ribosome biogenesis; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase activity, hydrolase activity, nucleic acid binding, nucleotide b...
Does Knockout of Ifna15 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Ifna15
autophagy
Embryonic Fibroblast Cell Line
Gene: Ifna15 (interferon alpha 15) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation involved in immune response, T cell activation involved in immune response, adaptive immune response, defense response, defense response to virus, humoral immune response,...
Does Knockout of Psmd3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Psmd3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Psmd3 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of protein catabolic process, ubiquitin-dependent protein catabolic process; MF: enzyme regulator activity, protein binding; CC: cytosol, nu...
Does Knockout of Spc24 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Spc24
cell proliferation
Mouse kidney carcinoma cell
Gene: Spc24 (SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: attachment of spindle microtubules to kinetochore, cell division, chromosome segregation, mitotic spindle assembly checkpoint signaling; CC: N...
Does Knockout of Gosr1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Gosr1
protein/peptide accumulation
Embryonic Cell Line
Gene: Gosr1 (golgi SNAP receptor complex member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endoplasmic reticulum to Golgi vesicle-mediated transport, inter-Golgi cisterna vesicle-mediated transport, protein transport, retrograde transport, endosome to Golgi, vesic...
Does Knockout of St3gal3 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
St3gal3
protein/peptide distribution
myoblast cell line
Gene: St3gal3 (ST3 beta-galactoside alpha-2,3-sialyltransferase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ganglioside biosynthetic process via lactosylceramide, protein glycosylation; MF: N-acetyllactosaminide alpha-2,3-sialyltransferase activity, beta-galactosid...
Does Knockout of Myo5a in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Myo5a
cell cycle progression
breast epithelium
Gene: Myo5a (myosin VA) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament organization, actin filament-based movement, axo-dendritic protein transport, cellular response to insulin stimulus, chemical synaptic transmission, developmental pigmentation, dopamine...
Does Knockout of Mrpl19 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Mrpl19
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mrpl19 (mitochondrial ribosomal protein L19) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrial riboso...
Does Knockout of Lrrc49 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Lrrc49
response to virus
Microglial Cell Line
Gene: Lrrc49 (leucine rich repeat containing 49) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cilium disassembly, microtubule cytoskeleton organization, microtubule polymerization; CC: centriolar satellite, cytoplasm, cytoskeleton, cytosol, microtubule Pathway...
Does Knockout of Stac2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Stac2
protein/peptide accumulation
Embryonic Cell Line
Gene: Stac2 (SH3 and cysteine rich domain 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of protein localization to plasma membrane, positive regulation of voltage-gated calcium channel activity, skeletal muscle contraction; MF: metal ion binding, ...
Does Knockout of Copg1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Copg1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Copg1 (coatomer protein complex, subunit gamma 1) Type: protein-coding Summary: Predicted to enable structural molecule activity. Predicted to be involved in several processes, including Golgi vesicle transport; establishment of Golgi localization; and organelle transport along microtubule. Locate...
Does Knockout of Slu7 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Slu7
protein/peptide accumulation
Embryonic Cell Line
Gene: Slu7 (SLU7 splicing factor homolog (S. cerevisiae)) Type: protein-coding Summary: Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicin...
Does Knockout of Mmp27 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Mmp27
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Mmp27 (matrix metallopeptidase 27) Type: protein-coding Summary: No summary available. Gene Ontology: BP: collagen catabolic process, extracellular matrix organization, proteolysis; MF: hydrolase activity, metal ion binding, metalloendopeptidase activity, metallopeptidase activity, peptid...
Does Knockout of Sap18b in Colonic Cancer Cell Line causally result in cell proliferation?
1
2,176
Knockout
Sap18b
cell proliferation
Colonic Cancer Cell Line
Gene: Sap18b (Sin3-associated polypeptide 18B) Type: protein-coding Summary: This intronless gene is highly similar to the multi-exon Sap18 gene on chromosome 14, whose product functions in transcriptional repression as a component of the Sin3 histone deacetylase complex. This gene may possibly be a Sap...
Does Knockout of U2surp in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
U2surp
cell proliferation
Embryonic Stem Cell Line
Gene: U2surp (U2 snRNP-associated SURP domain containing) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA processing, biological_process; MF: RNA binding, molecular_function, nucleic acid binding; CC: U2 snRNP, nucleoplasm, nucleus Pathways: Metabolism of RNA...
Does Knockout of B3galt4 in Regulatory T cell causally result in cell proliferation?
1
2,127
Knockout
B3galt4
cell proliferation
Regulatory T cell
Gene: B3galt4 (UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ganglioside biosynthetic process, lipid metabolic process, protein O-linked glycosylation, protein glycosylation; MF: N-acetyl-beta-D-glucosami...
Does Knockout of Spaca6 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Spaca6
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Spaca6 (sperm acrosome associated 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fusion of sperm to egg plasma membrane involved in single fertilization, single fertilization, sperm-egg recognition; MF: molecular_function, protein-macromolecule adaptor activity;...
Does Knockout of Zfp628 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Zfp628
response to chemicals
Pancreatic Cancer Cell Line
Gene: Zfp628 (zinc finger protein 628) Type: protein-coding Summary: No summary available. Gene Ontology: BP: developmental process, positive regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II, spermatoge...
Does Knockout of Fyco1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Fyco1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Fyco1 (FYVE and coiled-coil domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: plus-end-directed vesicle transport along microtubule, positive regulation of autophagosome maturation; MF: metal ion binding, zinc ion binding; CC: Golgi apparatus, aut...
Does Knockout of Wdr1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Wdr1
cell proliferation
Melanoma Cell Line
Gene: Wdr1 (WD repeat domain 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, actin filament depolymerization, actin filament fragmentation, apical junction assembly, cortical cytoskeleton organization, establishment of planar polarity o...
Does Knockout of Rnf43 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Rnf43
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rnf43 (ring finger protein 43) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt receptor catabolic process, Wnt signaling pathway, negative regulation of Wnt signaling pathway, protein ubiquitination, stem cell proliferation, ubiquitin-dependent protein catabolic...
Does Knockout of Hic1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Hic1
cell proliferation
Embryonic Stem Cell Line
Gene: Hic1 (hypermethylated in cancer 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, intrinsic apoptotic signaling pathway in response to DNA damage, negative regulation of Wnt signaling pathway, negative regulation of transcription by RNA polym...
Does Knockout of Wfdc10 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Wfdc10
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Wfdc10 (WAP four-disulfide core domain 10) Type: protein-coding Summary: Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be active in extracellular space. Orthologous to several hu...
Does Knockout of Dnaja3 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Dnaja3
cell proliferation
Colonic Cancer Cell Line
Gene: Dnaja3 (DnaJ heat shock protein family (Hsp40) member A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell differentiation in thymus, activation-induced cell death of T cells, apoptotic process, cellular senescence, immune system process, mitochondrial DNA rep...
Does Knockout of Prpf40b in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Prpf40b
protein/peptide distribution
myoblast cell line
Gene: Prpf40b (pre-mRNA processing factor 40B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA cis splicing, via spliceosome, mRNA processing, mRNA splicing, via spliceosome; CC: U1 snRNP, U2-type prespliceosome, nuclear matrix, nuclear speck, nucleus ...
Does Knockout of Hells in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Hells
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Hells (helicase, lymphoid specific) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA methylation-dependent constitutive heterochromatin formation, cell division, cellular response to leukemia inhibitory factor, chromatin remodeling, chromosomal DNA methylation ma...
Does Knockout of Mcur1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,288
Knockout
Mcur1
cell proliferation
Mouse kidney carcinoma cell
Gene: Mcur1 (mitochondrial calcium uniporter regulator 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium import into the mitochondrion, calcium ion import, calcium ion transmembrane transport, calcium ion transport, cell migration, cell population proliferation, ...
Does Knockout of Cpsf1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Cpsf1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cpsf1 (cleavage and polyadenylation specific factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA 3'-end processing, mRNA processing; MF: RNA binding, enzyme binding, mRNA 3'-UTR AU-rich region binding, nucleic acid binding; CC: mRNA cleavage and polyadenyl...
Does Knockout of Pfkfb4 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Pfkfb4
protein/peptide distribution
myoblast cell line
Gene: Pfkfb4 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate phosphorylation, fructose 2,6-bisphosphate metabolic process, fructose metabolic process, gluconeogenesis, glycolytic process; MF: 6-phosphofr...
Does Knockout of Pggt1b in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
1
1,522
Knockout
Pggt1b
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Pggt1b (protein geranylgeranyltransferase type I, beta subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of cell cycle, positive regulation of cell population proliferation, protein geranylgeranylation; MF: CAAX-protein geranylgeranyltrans...
Does Knockout of Mall in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Mall
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mall (mal, T cell differentiation protein-like) Type: protein-coding Summary: No summary available. Gene Ontology: CC: Golgi membrane, clathrin-coated vesicle, cytoplasmic vesicle, membrane, membrane raft, plasma membrane Pathways: UniProt: Q91X49 Entrez ID: 228...
Does Knockout of Utp15 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Utp15
protein/peptide distribution
myoblast cell line
Gene: Utp15 (UTP15 small subunit processome component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of rRNA processing, positive regulation of transcription by RNA polymerase I, rRNA processing, ribosomal small subunit biogenesis, ribosome biogenesi...
Does Knockout of Ric8a in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Ric8a
cell proliferation
Colonic Cancer Cell Line
Gene: Ric8a (RIC8 guanine nucleotide exchange factor A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, basement membrane organization, cell migration ...
Does Knockout of Fabp6 in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
0
1,522
Knockout
Fabp6
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Fabp6 (fatty acid binding protein 6) Type: protein-coding Summary: The protein encoded by this gene is part of the fatty acid binding protein family (FABP). FABPs are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands and partic...
Does Knockout of Gjd3 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Gjd3
cell cycle progression
breast epithelium
Gene: Gjd3 (gap junction protein, delta 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: AV node cell to bundle of His cell communication by electrical coupling, cell communication, cell-cell signaling, gap junction assembly, monoatomic ion transmembrane transport, nega...
Does Knockout of Ces2b in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Ces2b
autophagy
Embryonic Fibroblast Cell Line
Gene: Ces2b (carboxyesterase 2B) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carboxylesterase activity, carboxylic ester hydrolase activity, hydrolase activity Pathways: Aspirin ADME, Biological oxidations, Drug ADME, Drug metabolism - other enzymes - Mus mus...
Does Knockout of Avil in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Avil
cell proliferation
Colonic Cancer Cell Line
Gene: Avil (advillin) Type: protein-coding Summary: Predicted to enable Arp2/3 complex binding activity; actin filament binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in positive regulation of neuron projection development. Predicted to be located in several cellu...
Does Knockout of Pam16 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Pam16
cell proliferation
Embryonic Stem Cell Line
Gene: Pam16 (presequence translocase-asssociated motor 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA biosynthetic process, negative regulation of apoptotic signaling pathway, ossification, protein import into mitochondrial matrix, protein transport; CC: PAM comp...
Does Knockout of Akap10 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Akap10
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Akap10 (A kinase anchor protein 10) Type: protein-coding Summary: This gene encodes a member of A-kinase anchoring proteins (AKAPs), a family of functionally related proteins that target protein kinase A to discrete locations within the cell. The encoded protein is localized to mitochondria and in...
Does Knockout of Otc in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Otc
protein/peptide distribution
myoblast cell line
Gene: Otc (ornithine transcarbamylase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-arginine biosynthetic process, L-arginine biosynthetic process via ornithine, L-ornithine catabolic process, amino acid biosynthetic process, amino acid metabolic process, ammonium ho...
Does Knockout of Nmd3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Nmd3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nmd3 (NMD3 ribosome export adaptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of RNA biosynthetic process, positive regulation of protein localization to nucleolus, protein transport, ribosomal large subunit export from nucleus; MF: protein...
Does Knockout of Nup188 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Nup188
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nup188 (nucleoporin 188) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA export from nucleus, mRNA transport, nucleocytoplasmic transport, protein import into nucleus, protein transport; MF: structural constituent of nuclear pore; CC: nuclear envelope, nuclear p...