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Does Knockout of Hhatl in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,440
Knockout
Hhatl
protein/peptide accumulation
Embryonic Cell Line
Gene: Hhatl (hedgehog acyltransferase-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of N-terminal protein palmitoylation, regulation of protein modification process; CC: endoplasmic reticulum, endoplasmic reticulum membrane, membrane, perinucle...
Does Knockout of Zfp773 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Zfp773
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Zfp773 (zinc finger protein 773) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Hoxc6 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Hoxc6
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Hoxc6 (homeobox C6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterior/posterior pattern specification, embryonic skeletal system development, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-bin...
Does Knockout of Gfi1b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Gfi1b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gfi1b (growth factor independent 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of granulocyte differentiation, positive regulation of transcription by RNA polymerase II, regulation of erythrocyte differentiation, regulation of hemopoiesis, ...
Does Knockout of Lap3 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,043
Knockout
Lap3
autophagy
Embryonic Fibroblast Cell Line
Gene: Lap3 (leucine aminopeptidase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteolysis; MF: aminopeptidase activity, carboxypeptidase activity, hydrolase activity, manganese ion binding, metal ion binding, metalloaminopeptidase activity, peptidase activity; CC:...
Does Knockout of Aldh1a1 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Aldh1a1
cell viability
Immortal mouse chromaffin cells
Gene: Aldh1a1 (aldehyde dehydrogenase family 1, subfamily A1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 9-cis-retinoic acid biosynthetic process, 9-cis-retinoic acid metabolic process, aldehyde metabolic process, cellular detoxification of aldehyde, embryonic eye mo...
Does Knockout of Ric1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Ric1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ric1 (RAB6A GEF complex partner 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cranial skeletal system development, intracellular protein transport, negative regulation of protein catabolic process, positive regulation of GTPase activity, regulation of extracell...
Does Knockout of Foxn1 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Foxn1
response to virus
Microglial Cell Line
Gene: Foxn1 (forkhead box N1) Type: protein-coding Summary: The protein encoded by this gene is part of the forkhead family or 'winged-helix' transcription factors that are important in developmental processes, immune system regulation, metabolism, cancer and aging. This gene family has over 100 members...
Does Knockout of Pcna in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Pcna
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Pcna (proliferating cell nuclear antigen) Type: protein-coding Summary: Enables enzyme binding activity. Involved in mitotic telomere maintenance via semi-conservative replication and replication fork processing. Acts upstream of or within base-excision repair, gap-filling; cellular response to xe...
Does Knockout of Klk9 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Klk9
response to virus
Microglial Cell Line
Gene: Klk9 (kallikrein related-peptidase 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, protein maturation, proteolysis; MF: hydrolase activity, molecular_function, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activ...
Does Knockout of Rassf9 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Rassf9
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rassf9 (Ras association (RalGDS/AF-6) domain family (N-terminal) member 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular transport, signal transduction; MF: enzyme binding, protein domain specific binding; CC: cytosol, endosome, recycling endosome, t...
Does Knockout of Dpys in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Dpys
cell proliferation
Embryonic Stem Cell Line
Gene: Dpys (dihydropyrimidinase) Type: protein-coding Summary: Enables dihydropyrimidinase activity and phosphoprotein binding activity. Involved in pyrimidine nucleoside monophosphate catabolic process. Is active in cytosol. Is expressed in cranium. Human ortholog(s) of this gene implicated in dihydrop...
Does Knockout of Mettl5 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Mettl5
cell proliferation
Embryonic Stem Cell Line
Gene: Mettl5 (methyltransferase 5, N6-adenosine) Type: protein-coding Summary: No summary available. Gene Ontology: BP: methylation, positive regulation of translation, rRNA methylation, rRNA processing, stem cell differentiation; MF: S-adenosyl-L-methionine binding, S-adenosylmethionine-depend...
Does Knockout of Hrh3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Hrh3
cell proliferation
Mouse kidney carcinoma cell
Gene: Hrh3 (histamine receptor H3) Type: protein-coding Summary: Predicted to enable several functions, including amine binding activity; histamine receptor activity; and neurotransmitter receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pat...
Does Knockout of Med12 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Med12
response to virus
Microglial Cell Line
Gene: Med12 (mediator complex subunit 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Schwann cell development, Wnt signaling pathway, planar cell polarity pathway, axis elongation involved in somitogenesis, embryonic brain development, embryonic neurocranium morphoge...
Does Knockout of Kmt2b in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Kmt2b
cell proliferation
Melanoma Cell Line
Gene: Kmt2b (lysine (K)-specific methyltransferase 2B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA methylation-dependent constitutive heterochromatin formation, chromatin organization, epigenetic regulation of gene expression, maternal-to-zygotic transition of gen...
Does Knockout of Cpne2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Cpne2
cell viability
Immortal mouse chromaffin cells
Gene: Cpne2 (copine II) Type: protein-coding Summary: Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encodes a calcium-dependent protein containing two N-terminal type II C2 domains and...
Does Knockout of Arl13a in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Arl13a
cell proliferation
Melanoma Cell Line
Gene: Arl13a (ADP-ribosylation factor-like 13A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: non-motile cilium assembly, receptor localization to non-motile cilium; MF: GTP binding, GTPase activity, nucleotide binding; CC: ciliary membrane, cilium, motile cilium, non-m...
Does Knockout of Kdm5a in Melanoma Cell Line causally result in tumorigenicity?
1
616
Knockout
Kdm5a
tumorigenicity
Melanoma Cell Line
Gene: Kdm5a (lysine demethylase 5A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, circadian regulation of gene expression, facultative heterochromatin formation, male gonad development, negative regulation of transcription b...
Does Knockout of Ccl9 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Ccl9
protein/peptide accumulation
Regulatory T cell
Gene: Ccl9 (C-C motif chemokine ligand 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antimicrobial humoral immune response mediated by antimicrobial peptide, cell chemotaxis, chemokine-mediated signaling pathway, chemotaxis, immune response, inflammatory response, ne...
Does Knockout of Mfsd11 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Mfsd11
protein/peptide distribution
myoblast cell line
Gene: Mfsd11 (major facilitator superfamily domain containing 11) Type: protein-coding Summary: Acts upstream of or within response to food and response to starvation. Predicted to be located in membrane. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system; liv...
Does Knockout of Psg18 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Psg18
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Psg18 (pregnancy specific beta-1-glycoprotein 18) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytokinin biosynthetic process, positive regulation of gene expression, regulation of immune system process, regulation of interleukin-10 production, signal transductio...
Does Knockout of 4930555G01Rik in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
4930555G01Rik
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: 4930555G01Rik (RIKEN cDNA 4930555G01 gene) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Tsc1 in Lung Cancer Cell Line causally result in tumorigenicity?
1
1,089
Knockout
Tsc1
tumorigenicity
Lung Cancer Cell Line
Gene: Tsc1 (TSC complex subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-glucose import, TORC1 signaling, adaptive immune response, adult locomotory behavior, associative learning, cardiac muscle cell differentiation, cell projection organization, cell-matrix ...
Does Knockout of Rasl10b in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Rasl10b
response to virus
Microglial Cell Line
Gene: Rasl10b (RAS-like, family 10, member B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of peptide hormone secretion, regulation of systemic arterial blood pressure by atrial natriuretic peptide; MF: G protein activity, GTP binding, GTPase activi...
Does Knockout of Dok4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Dok4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dok4 (docking protein 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor protein tyrosine kinase signaling pathway, nervous system development, positive regulation of MAPK cascade Pathways: Axon guidance, Developmental Biology, Nervous...
Does Knockout of Kctd20 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Kctd20
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Kctd20 (potassium channel tetramerisation domain containing 20) Type: protein-coding Summary: No summary available. Gene Ontology: MF: identical protein binding, protein binding; CC: cytoplasm Pathways: UniProt: Q8CDD8 Entrez ID: 66989
Does Knockout of Mmp21 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Mmp21
cell viability
Immortal mouse chromaffin cells
Gene: Mmp21 (matrix metallopeptidase 21) Type: protein-coding Summary: This gene encodes a member of the matrix metalloproteinase family of extracellular matrix-degrading enzymes that are involved in tissue remodeling, wound repair, progression of atherosclerosis and tumor invasion. Mice harboring certa...
Does Knockout of Arhgef2 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Arhgef2
protein/peptide distribution
myoblast cell line
Gene: Arhgef2 (Rho/Rac guanine nucleotide exchange factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament organization, asymmetric neuroblast division, cell differentiation, cell division, cell morphogenesis, cellular response to muramyl dipeptide, estab...
Does Knockout of Trmu in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Trmu
protein/peptide distribution
myoblast cell line
Gene: Trmu (tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: tRNA processing, tRNA wobble position uridine thiolation; MF: ATP binding, RNA binding, nucleotide binding, sulfurtransferase activity, tRNA binding, tR...
Does Knockout of Vmn1r7 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Vmn1r7
protein/peptide accumulation
Embryonic Cell Line
Gene: Vmn1r7 (vomeronasal 1 receptor 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromone bi...
Does Knockout of Srp9 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Srp9
cell proliferation
Colonic Cancer Cell Line
Gene: Srp9 (signal recognition particle 9) Type: protein-coding Summary: Predicted to enable 7S RNA binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Is expresse...
Does Knockout of Tomm40 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Tomm40
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Tomm40 (translocase of outer mitochondrial membrane 40) Type: protein-coding Summary: Predicted to enable monoatomic cation channel activity; preprotein binding activity; and protein transmembrane transporter activity. Predicted to be involved in positive regulation of apoptotic process; protein i...
Does Knockout of Ywhae in Lymphoma Cell Line causally result in response to chemicals?
1
1,547
Knockout
Ywhae
response to chemicals
Lymphoma Cell Line
Gene: Ywhae (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to plasma membrane transport, MAPK cascade, cellular response to heat, cerebral cortex development, cytoplasmic ...
Does Knockout of Arhgap23 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Arhgap23
cell proliferation
Colonic Cancer Cell Line
Gene: Arhgap23 (Rho GTPase activating protein 23) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: RAC1 GTPase cycle, RHO GTPase cycle, RHOA GTPase cycle, Signal Transduction, Signaling by Rho GTPases, Signaling by Rho GTPases, Miro GTPases and RHOBTB3 ...
Does Knockout of Rap2b in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Rap2b
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Rap2b (RAP2B, member of RAS oncogene family) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rap protein signal transduction, negative regulation of cell migration, platelet activation, platelet aggregation, regulation of protein tyrosine kinase activity, signal tra...
Does Knockout of Cacna1h in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Cacna1h
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit) Type: protein-coding Summary: Voltage-dependent Ca(2+) channels mediate the entry of Ca(2+) ions into excitable cells and are involved in a variety of Ca(2+)-dependent processes, including muscle contraction, hormone or neurotr...
Does Knockout of Sec24b in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Sec24b
response to virus
Embryonic Fibroblast Cell Line
Gene: Sec24b (SEC24 homolog B, COPII coat complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: COPII-coated vesicle cargo loading, aorta morphogenesis, auditory receptor cell morphogenesis, auditory receptor cell stereocilium organization, circulatory system...
Does Knockout of Hsd17b2 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Hsd17b2
autophagy
Embryonic Fibroblast Cell Line
Gene: Hsd17b2 (hydroxysteroid (17-beta) dehydrogenase 2) Type: protein-coding Summary: Predicted to enable estradiol 17-beta-dehydrogenase [NAD(P)+] activity and testosterone dehydrogenase (NAD+) activity. Acts upstream of or within in utero embryonic development and placenta development. Predicted to b...
Does Knockout of Tdh in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Tdh
cell viability
Immortal mouse chromaffin cells
Gene: Tdh (L-threonine dehydrogenase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-threonine catabolic process, L-threonine catabolic process to glycine; MF: L-threonine 3-dehydrogenase activity, identical protein binding, oxidoreductase activity; CC: mitochondrion ...
Does Knockout of Xrn1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Xrn1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Xrn1 (5'-3' exoribonuclease 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA metabolic process, RNA processing, histone mRNA catabolic process, meiotic cell cycle, negative regulation of translation, nuclear mRNA surveillance, nuclear-transcribed mRNA cataboli...
Does Knockout of Glp1r in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Glp1r
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Glp1r (glucagon-like peptide 1 receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, associative learning, cAMP/PKA signal transduction, cell...
Does Knockout of Map10 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Map10
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Map10 (microtubule-associated protein 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, cytoplasmic microtubule organization, microtubule cytoskeleton organization, mitotic spindle midzone assembly, positive regulation of cytokinesis, regulation of ...
Does Knockout of Cyb5r1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Cyb5r1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cyb5r1 (cytochrome b5 reductase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid metabolic process, steroid biosynthetic process, steroid metabolic process, sterol biosynthetic process; MF: FAD binding, cytochrome-b5 reductase activity, acting on NAD(P)H, ox...
Does Knockout of Rdh16f2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Rdh16f2
cell proliferation
Mouse kidney carcinoma cell
Gene: Rdh16f2 (RDH16 family member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: androgen biosynthetic process, positive regulation of retinoic acid biosynthetic process, retinoic acid metabolic process, retinol metabolic process, steroid metabolic process; MF: all-t...
Does Knockout of Fance in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Fance
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Fance (Fanconi anemia, complementation group E) Type: protein-coding Summary: This gene encodes the complementation group E subunit of the multimeric Fanconi anemia (FA) nuclear complex composed of proteins encoded by over ten Fanconi anemia complementation (FANC) group genes: FANCA, FANCB, FANCC,...
Does Knockout of Ogdh in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Ogdh
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ogdh (oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 2-oxoglutarate decarboxylation to succinyl-CoA, 2-oxoglutarate metabolic process, cerebellar cortex development, generation of precursor metabolites a...
Does Knockout of Bri3 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Bri3
cell cycle progression
breast epithelium
Gene: Bri3 (brain protein I3) Type: protein-coding Summary: No summary available. Gene Ontology: MF: identical protein binding; CC: cytoplasm, lysosomal membrane, lysosome, membrane, perinuclear region of cytoplasm Pathways: Immune System, Innate Immune System, Neutrophil degranulation...
Does Knockout of Necab1 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Necab1
cell cycle progression
breast epithelium
Gene: Necab1 (N-terminal EF-hand calcium binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blastocyst hatching, regulation of amyloid precursor protein biosynthetic process; MF: calcium ion binding, identical protein binding, metal ion binding; CC: cilium...
Does Knockout of Vgll2 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Vgll2
cell proliferation
Melanoma Cell Line
Gene: Vgll2 (vestigial like family member 2) Type: protein-coding Summary: This gene is a member of the Vestigial-like (Vgl) gene family and is upregulated during muscle differentiation. The product of this gene interacts with and modifies the DNA-binding properties of the transcription factor, TEF-1, a...
Does Knockout of Urgcp in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Urgcp
cell proliferation
Regulatory T cell
Gene: Urgcp (upregulator of cell proliferation) Type: protein-coding Summary: No summary available. Gene Ontology: MF: GTP binding, molecular_function, nucleotide binding; CC: cytoplasm, cytosol, nucleus Pathways: UniProt: Q5NCI0 Entrez ID: 72046
Does Knockout of Nlrx1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Nlrx1
cell proliferation
Embryonic Stem Cell Line
Gene: Nlrx1 (NLR family member X1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: immune system process, innate immune response, negative regulation of RIG-I signaling pathway, negative regulation of canonical NF-kappaB signal transduction, negative regulation of inflamm...
Does Knockout of Pstpip2 in Melanoma Cell Line causally result in cell proliferation?
1
1,157
Knockout
Pstpip2
cell proliferation
Melanoma Cell Line
Gene: Pstpip2 (proline-serine-threonine phosphatase-interacting protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: actin binding, protein binding; CC: cytoplasm, cytoskeleton, cytosol, membrane, plasma membrane Pathways: UniProt: Q99M15 ...
Does Knockout of Gatd1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Gatd1
protein/peptide distribution
myoblast cell line
Gene: Gatd1 (glutamine amidotransferase like class 1 domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lactate biosynthetic process, methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione; CC: cytoplasm, early endosome, endosome, extrace...
Does Knockout of Esrrg in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Esrrg
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Esrrg (estrogen-related receptor gamma) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nuclear receptor-mediated steroid hormone signaling pathway, positive regulation of DNA-templated transcription, positive regulation of cold-induced thermogenesis, positive regul...
Does Knockout of Ddx59 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ddx59
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ddx59 (DEAD box helicase 59) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase activity, hydrolase activity, mRNA binding, metal ion binding, nucleic acid binding, nucleotide binding, z...
Does Knockout of Pdzd2 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Pdzd2
protein/peptide distribution
Microglial Cell Line
Gene: Pdzd2 (PDZ domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: CC: apical part of cell, cell-cell junction, centriolar satellite, cytoplasm, cytosol, endoplasmic reticulum, extracellular region, nucleus, plasma membrane Pathways: UniP...
Does Knockout of Cdk2 in Lymphoma Cell Line causally result in response to chemicals?
0
1,536
Knockout
Cdk2
response to chemicals
Lymphoma Cell Line
Gene: Cdk2 (cyclin dependent kinase 2) Type: protein-coding Summary: Enables cyclin binding activity; cyclin-dependent protein serine/threonine kinase activity; and magnesium ion binding activity. Involved in peptidyl-serine phosphorylation and positive regulation of cell population proliferation. Acts ...
Does Knockout of Dll1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Dll1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dll1 (delta like canonical Notch ligand 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, Notch signaling pathway involved in arterial endothelial cell fate commitment, animal organ morphogenesis, astrocyte development, auditory receptor ce...
Does Knockout of Kcna1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Kcna1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Kcna1 (potassium voltage-gated channel, shaker-related subfamily, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: action potential, brain development, cell communication by electrical coupling, cellular response to magnesium ion, detection of mechanical st...
Does Knockout of Wwp1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Wwp1
cell proliferation
Embryonic Stem Cell Line
Gene: Wwp1 (WW domain containing E3 ubiquitin protein ligase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell differentiation, lung development, negative regulation of DNA-templated transcription, proteasome-mediated ubiquitin-dependent protein catabolic process,...
Does Knockout of Tnpo1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Tnpo1
cell proliferation
Embryonic Stem Cell Line
Gene: Tnpo1 (transportin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular protein transport, nucleocytoplasmic transport, protein import into nucleus, protein transport; MF: nuclear import signal receptor activity, nuclear localization sequence binding, pr...
Does Knockout of Bcas2 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Bcas2
cell proliferation
Melanoma Cell Line
Gene: Bcas2 (BCAS2 pre-mRNA processing factor) Type: protein-coding Summary: Acts upstream of or within several processes, including alternative mRNA splicing, via spliceosome; ovarian follicle development; and spindle assembly. Part of Prp19 complex. Is expressed in several structures, including centra...
Does Knockout of Tut1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Tut1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Tut1 (terminal uridylyl transferase 1, U6 snRNA-specific) Type: protein-coding Summary: Predicted to enable several functions, including RNA binding activity; enzyme-substrate adaptor activity; and nucleotidyltransferase activity. Predicted to be involved in U6 snRNA 3'-end processing and co-trans...
Does Knockout of C1qtnf7 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
C1qtnf7
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: C1qtnf7 (C1q and tumor necrosis factor related protein 7) Type: protein-coding Summary: Enables identical protein binding activity. Located in extracellular space. Is expressed in several structures, including adipose tissue; central nervous system; genitourinary system; gut; and skeleton. Ortholo...
Does Knockout of Gm4775 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Gm4775
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Gm4775 (predicted gene 4775) Type: pseudo Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 212084
Does Knockout of Rabgef1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Rabgef1
cell proliferation
Embryonic Stem Cell Line
Gene: Rabgef1 (RAB guanine nucleotide exchange factor (GEF) 1) Type: protein-coding Summary: Enables ubiquitin protein ligase activity. Involved in dendritic transport. Acts upstream of or within several processes, including negative regulation of macromolecule metabolic process; regulation of signal tr...
Does Knockout of Crls1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Crls1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Crls1 (cardiolipin synthase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cardiolipin biosynthetic process, lipid metabolic process, phospholipid biosynthetic process, response to phosphatidylethanolamine, response to thyroxine; MF: cardiolipin synthase (CMP-fo...
Does Knockout of Pecam1 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Pecam1
response to virus
Embryonic Fibroblast Cell Line
Gene: Pecam1 (platelet/endothelial cell adhesion molecule 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rho protein signal transduction, angiogenesis, bicellular tight junction assembly, blood vessel development, cell adhesion, cell migration, cell surface receptor s...
Does Knockout of Timm17a in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Timm17a
cell proliferation
Colonic Cancer Cell Line
Gene: Timm17a (translocase of inner mitochondrial membrane 17a) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of protein processing, protein import into mitochondrial matrix, protein transport; MF: enzyme binding, protein transmembrane transporter ac...
Does Knockout of Ubqln1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
2,173
Knockout
Ubqln1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ubqln1 (ubiquilin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, aggrephagy, autophagosome assembly, autophagosome maturation, autophagy, cellular response to hypoxia, macroautophagy, negative regulation of store-operated calcium channel activity, ...
Does Knockout of Pkig in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Pkig
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Pkig (protein kinase inhibitor, gamma) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of protein import into nucleus, negative regulation of transcription by RNA polymerase II; MF: cAMP-dependent protein kinase inhibitor activity, protein kinase...
Does Knockout of Nkx2-5 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Nkx2-5
protein/peptide distribution
myoblast cell line
Gene: Nkx2-5 (NK2 homeobox 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Purkinje myocyte differentiation, adult heart development, apoptotic process involved in heart morphogenesis, atrial cardiac muscle cell development, atrial cardiac muscle tissue development, at...
Does Knockout of Lmcd1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Lmcd1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Lmcd1 (LIM and cysteine-rich domains 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, positive regulation of calcineurin-NFAT signaling cascade, regulation of cardiac muscle hypertrophy; MF: metal ion bind...
Does Knockout of Arhgap22 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Arhgap22
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Arhgap22 (Rho GTPase activating protein 22) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, cell differentiation, negative regulation of small GTPase mediated signal transduction, regulation of postsynapse organization, regulation of small GTPase media...
Does Knockout of Slc16a5 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Slc16a5
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Slc16a5 (solute carrier family 16 (monocarboxylic acid transporters), member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monocarboxylic acid transport, transmembrane transport; MF: monocarboxylic acid transmembrane transporter activity, symporter activity, tr...
Does Knockout of Sf3b6 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Sf3b6
cell proliferation
Embryonic Stem Cell Line
Gene: Sf3b6 (splicing factor 3B, subunit 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, blastocyst formation, mRNA processing, mRNA splicing, via spliceosome; MF: RNA binding, mRNA binding, nucleic acid binding; CC: U12-type spliceosomal complex, U2-type...
Does Knockout of Zfp524 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Zfp524
protein/peptide distribution
myoblast cell line
Gene: Zfp524 (zinc finger protein 524) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, metal ion binding, sequence-specific double-stranded DNA b...
Does Knockout of Slc17a8 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Slc17a8
protein/peptide accumulation
Mouse cell
Gene: Slc17a8 (solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-glutamate import, L-glutamate transmembrane transport, chloride transmembrane transport, chloride transport, cochlea d...
Does Knockout of Prtn3 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Prtn3
cell viability
Immortal mouse chromaffin cells
Gene: Prtn3 (proteinase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell-cell junction maintenance, collagen catabolic process, mature conventional dendritic cell differentiation, membrane protein ectodomain proteolysis, negative regulation of phagocytosis, neutrop...
Does Knockout of Hsp90b1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Hsp90b1
cell proliferation
Melanoma Cell Line
Gene: Hsp90b1 (heat shock protein 90, beta (Grp94), member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, actin rod assembly, cellular response to ATP, cellular response to manganese ion, insulin processing, negative regulation of apoptotic process, posi...
Does Knockout of Srpk3 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Srpk3
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Srpk3 (serine/arginine-rich protein specific kinase 3) Type: protein-coding Summary: Enables protein serine/threonine kinase activity. Involved in muscle tissue development. Acts upstream of or within protein phosphorylation and skeletal muscle tissue development. Predicted to be active in cytopla...
Does Knockout of Nbeal2 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Nbeal2
response to virus
Microglial Cell Line
Gene: Nbeal2 (neurobeachin-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blood coagulation, intracellular protein localization, megakaryocyte development, myeloid cell differentiation, platelet alpha granule organization, platelet formation, wound healing; CC: c...
Does Knockout of Pmpcb in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Pmpcb
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Pmpcb (peptidase (mitochondrial processing) beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein processing, protein processing involved in protein targeting to mitochondrion, proteolysis; MF: endopeptidase activity, hydrolase activity, metal ion binding, m...
Does Knockout of Zdhhc4 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Zdhhc4
protein/peptide distribution
myoblast cell line
Gene: Zdhhc4 (zinc finger, DHHC domain containing 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic pattern recognition receptor signaling pathway, negative regulation of cell migration, positive regulation of cell migration, positive regulation of innate imm...
Does Knockout of Defb7 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Defb7
cell proliferation
Mouse kidney carcinoma cell
Gene: Defb7 (defensin beta 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell chemotaxis, defense response, defense response to bacterium, positive chemotaxis; MF: CCR6 chemokine receptor binding, chemoattractant activity, phosphatidylinositol-4,5-bisphosphate bindin...
Does Knockout of Npat in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Npat
cell proliferation
Embryonic Stem Cell Line
Gene: Npat (nuclear protein in the AT region) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell cycle G1/S phase transition, in utero embryonic development, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription, positive...
Does Knockout of Brd8 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Brd8
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Brd8 (bromodomain containing 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to thyroid hormone stimulus, chromatin organization, positive regulation of DNA-templated transcription, positive regulation of double-strand break repair via homologou...
Does Knockout of Fut7 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Fut7
protein/peptide accumulation
Embryonic Cell Line
Gene: Fut7 (fucosyltransferase 7) Type: protein-coding Summary: Enables alpha-(1->3)-fucosyltransferase activity. Involved in several processes, including leukocyte migration involved in inflammatory response; lymphocyte migration into lymph node; and regulation of leukocyte migration. Acts upstream of ...
Does Knockout of Taf1a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Taf1a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Taf1a (TATA-box binding protein associated factor, RNA polymerase I, A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: transcription by RNA polymerase I; MF: DNA binding, protein binding; CC: RNA polymerase I transcription regulator complex, RNA polymerase transcri...
Does Knockout of Rer1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Rer1
protein/peptide distribution
myoblast cell line
Gene: Rer1 (retention in endoplasmic reticulum sorting receptor 1) Type: protein-coding Summary: Enables acetylcholine receptor binding activity. Acts upstream of or within positive regulation of protein localization to plasma membrane and skeletal muscle acetylcholine-gated channel clustering. Located ...
Does Knockout of Ywhae in Lymphoma Cell Line causally result in response to chemicals?
1
1,531
Knockout
Ywhae
response to chemicals
Lymphoma Cell Line
Gene: Ywhae (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to plasma membrane transport, MAPK cascade, cellular response to heat, cerebral cortex development, cytoplasmic ...
Does Knockout of Egr1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Egr1
cell proliferation
Colonic Cancer Cell Line
Gene: Egr1 (early growth response 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: BMP signaling pathway, T cell differentiation, cellular response to gamma radiation, cellular response to heparin, cellular response to hypoxia, cellular response to interleukin-8, cellul...
Does Knockout of Clpx in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Clpx
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Clpx (caseinolytic mitochondrial matrix peptidase chaperone subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ATP metabolic process, protein folding, proteolysis, proteolysis involved in protein catabolic process; MF: ATP binding, ATP hydrolysis activity, ATP...
Does Knockout of Serpina1a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Serpina1a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Serpina1a (serine (or cysteine) peptidase inhibitor, clade A, member 1A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acute-phase response, protein N-linked glycosylation, response to chromate, response to cytokine, response to lead ion, response to methanol, res...
Does Knockout of Mgat3 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Mgat3
protein/peptide accumulation
Regulatory T cell
Gene: Mgat3 (mannoside acetylglucosaminyltransferase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: N-acetylglucosamine metabolic process, amyloid-beta metabolic process, cellular response to oxidative stress, cognition, intracellular protein localization, negative re...
Does Knockout of Gsg1l in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Gsg1l
response to virus
Microglial Cell Line
Gene: Gsg1l (GSG1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of cell communication, regulation of postsynaptic neurotransmitter receptor internalization, regulation of short-term neuronal synaptic plasticity, regulation of signaling, regulation of tr...
Does Knockout of Pkdcc in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Pkdcc
protein/peptide accumulation
Embryonic Cell Line
Gene: Pkdcc (protein kinase domain containing, cytoplasmic) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bone mineralization, cell differentiation, embryonic digestive tract development, limb morphogenesis, lung alveolus development, multicellular organism growth, nega...
Does Knockout of Arhgap8 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Arhgap8
cell proliferation
Regulatory T cell
Gene: Arhgap8 (Rho GTPase activating protein 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of endocytic recycling, positive regulation of ERK1 and ERK2 cascade, signal transduction, small GTPase-mediated signal transduction; MF: GTPase activator a...
Does Knockout of Ufl1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Ufl1
cell proliferation
Colonic Cancer Cell Line
Gene: Ufl1 (UFM1 specific ligase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage checkpoint signaling, DNA damage response, DNA damage response, signal transduction by p53 class mediator, DNA double-strand break processing, DNA repair, NLRP3 inflammasome com...