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Does Knockout of Nipa2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Nipa2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nipa2 (non imprinted in Prader-Willi/Angelman syndrome 2 homolog (human)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: magnesium ion transmembrane transport, magnesium ion transport, monoatomic ion transport; MF: magnesium ion transmembrane transporter activity, ...
Does Knockout of Naa50 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Naa50
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Naa50 (N(alpha)-acetyltransferase 50, NatE catalytic subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: N-terminal protein amino acid acetylation, chromatin remodeling, establishment of mitotic sister chromatid cohesion, mitotic sister chromatid cohesion, mito...
Does Knockout of Psmb5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Psmb5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Psmb5 (proteasome (prosome, macropain) subunit, beta type 5) Type: protein-coding Summary: Enables peptidase activity. Acts upstream of or within proteasome-mediated ubiquitin-dependent protein catabolic process and response to oxidative stress. Part of proteasome core complex. Is expressed in emb...
Does Knockout of Kif23 in Microglial Cell Line causally result in response to virus?
1
1,438
Knockout
Kif23
response to virus
Microglial Cell Line
Gene: Kif23 (kinesin family member 23) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, microtubule-based movement, mitotic cytokinesis, mitotic spindle midzone assembly, positive regulation of cytokinesis; MF: ATP binding, ATP hydrolysis activity, microtubu...
Does Knockout of Plch1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Plch1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Plch1 (phospholipase C, eta 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular signal transduction, lipid catabolic process, lipid metabolic process, phosphatidylinositol metabolic process, phosphatidylinositol-mediated signaling, release of sequestere...
Does Knockout of Ssbp3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Ssbp3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ssbp3 (single-stranded DNA binding protein 3) Type: protein-coding Summary: This gene encodes a member of the Ssdp (sequence-specific single-stranded DNA binding protein) family of proteins. The encoded protein binds specifically to single-stranded pyrimidine-rich DNA elements. The encoded protein...
Does Knockout of Ola1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Ola1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ola1 (Obg-like ATPase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ATP metabolic process; MF: ATP binding, ATP hydrolysis activity, GTP binding, hydrolase activity, metal ion binding, nucleotide binding, ribosomal large subunit binding, ribosome binding; CC: c...
Does Knockout of Atp6v0e in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Atp6v0e
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Atp6v0e (ATPase, H+ transporting, lysosomal V0 subunit E) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transport, proton transmembrane transport, transmembrane transport; MF: proton-transporting ATPase activity, rotational mechanism; CC: membrane, ...
Does Knockout of Ankrd46 in Melanoma Cell Line causally result in cell proliferation?
1
1,158
Knockout
Ankrd46
cell proliferation
Melanoma Cell Line
Gene: Ankrd46 (ankyrin repeat domain 46) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8BTZ5 Entrez ID: 68839
Does Knockout of Tox in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Tox
protein/peptide accumulation
Regulatory T cell
Gene: Tox (thymocyte selection-associated high mobility group box) Type: protein-coding Summary: Enables chromatin DNA binding activity. Involved in several processes, including alpha-beta T cell lineage commitment; cerebral cortex neuron differentiation; and regulation of positive thymic T cell selecti...
Does Knockout of Nvl in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Nvl
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nvl (nuclear VCP-like) Type: protein-coding Summary: Predicted to enable ATP binding activity; ATP hydrolysis activity; and preribosome binding activity. Predicted to be involved in rRNA processing; regulation of protein localization to nucleolus; and ribosomal large subunit biogenesis. Predicted ...
Does Knockout of Synj2bp in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Synj2bp
protein/peptide distribution
myoblast cell line
Gene: Synj2bp (synaptojanin 2 binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rho protein signal transduction, cytoplasm organization, endocytosis, intracellular distribution of mitochondria, negative regulation of ERK1 and ERK2 cascade, negative regulati...
Does Knockout of Rangap1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Rangap1
cell proliferation
Embryonic Stem Cell Line
Gene: Rangap1 (RAN GTPase activating protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to peptide hormone stimulus, cellular response to vasopressin, negative regulation of protein export from nucleus, nuclear export, protein sumoylation, respon...
Does Knockout of Htra3 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Htra3
protein/peptide distribution
myoblast cell line
Gene: Htra3 (HtrA serine peptidase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of BMP signaling pathway, negative regulation of transforming growth factor beta receptor signaling pathway, proteolysis; MF: endopeptidase activity, hydrolase activi...
Does Knockout of Gtf2h2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Gtf2h2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gtf2h2 (general transcription factor II H, polypeptide 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA-templated transcription, nucleotide-excision repair, regulation of transcription by RNA polymerase II, transcription by RNA...
Does Knockout of Podnl1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Podnl1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Podnl1 (podocan-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: extracellular matrix, extracellular region, extracellular space Pathways: UniProt: Q6P3Y9 Entrez ID: 244550
Does Knockout of Prkg2 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Prkg2
cell proliferation
Embryonic Stem Cell Line
Gene: Prkg2 (protein kinase, cGMP-dependent, type II) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular hypotonic response, circadian regulation of gene expression, circadian rhythm, negative regulation of cell volume, negative regulation of chloride transport, pos...
Does Knockout of Rdh1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Rdh1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Rdh1 (retinol dehydrogenase 1 (all trans)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: androgen biosynthetic process, positive regulation of retinoic acid biosynthetic process, retinoic acid metabolic process, retinoid metabolic process, retinol metabolic proces...
Does Knockout of Ifna12 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Ifna12
protein/peptide distribution
myoblast cell line
Gene: Ifna12 (interferon alpha 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation involved in immune response, T cell activation involved in immune response, adaptive immune response, defense response, defense response to virus, humoral immune response,...
Does Knockout of Cdh20 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Cdh20
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cdh20 (cadherin 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adherens junction organization, calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules, cell adhesion, cell migration, cell morphogenesis, cell-cell adhesion, cell-cell adh...
Does Knockout of Chd4 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Chd4
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Chd4 (chromodomain helicase DNA binding protein 4) Type: protein-coding Summary: Enables DNA-binding transcription factor binding activity. Predicted to be involved in several processes, including double-strand break repair via homologous recombination; negative regulation of macromolecule biosynt...
Does Knockout of Mamdc2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Mamdc2
cell viability
Immortal mouse chromaffin cells
Gene: Mamdc2 (MAM domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: CC: endoplasmic reticulum, extracellular matrix, extracellular region, interstitial matrix, membrane Pathways: UniProt: Q8CG85 Entrez ID: 71738
Does Knockout of Trnp1 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Trnp1
phagocytosis
macrophage
Gene: Trnp1 (TMF1-regulated nuclear protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cerebellar cortex morphogenesis, nervous system development, neural precursor cell proliferation, regulation of cell cycle, regulation of cell population proliferation; MF: DNA ...
Does Knockout of Eomes in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Eomes
protein/peptide accumulation
Embryonic Cell Line
Gene: Eomes (eomesodermin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CD8-positive, alpha-beta T cell differentiation involved in immune response, adaptive immune response, anatomical structure morphogenesis, astrocyte differentiation, blastocyst development, brain d...
Does Knockout of Traf3ip1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Traf3ip1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Traf3ip1 (TRAF3 interacting protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, cell projection organization, cilium assembly, dorsal/ventral neural tube patterning, embryonic camera-type eye development, embryonic digit morphogenesi...
Does Knockout of Cox6a1 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Cox6a1
cell proliferation
Regulatory T cell
Gene: Cox6a1 (cytochrome c oxidase subunit 6A1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial electron transport, cytochrome c to oxygen, oxidative phosphorylation; MF: enzyme regulator activity, oxidoreductase activity; CC: membrane, mitochondrial inner m...
Does Knockout of Ctcf in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Ctcf
cell viability
Immortal mouse chromaffin cells
Gene: Ctcf (CCCTC-binding factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA methylation-dependent constitutive heterochromatin formation, cardiac muscle cell development, cardiac muscle cell differentiation, chromatin looping, chromatin organization, chromosome ...
Does Knockout of Alas2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Alas2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Alas2 (aminolevulinic acid synthase 2, erythroid) Type: protein-coding Summary: No summary available. Gene Ontology: BP: erythrocyte development, erythrocyte differentiation, heme B biosynthetic process, heme biosynthetic process, hemoglobin biosynthetic process, intracellular iron ion ho...
Does Knockout of Snrpd1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Snrpd1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Snrpd1 (small nuclear ribonucleoprotein D1) Type: protein-coding Summary: Predicted to enable RNA binding activity and U1 snRNP binding activity. Predicted to be involved in spliceosomal snRNP assembly. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in connective tissu...
Does Knockout of Galnt12 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Galnt12
tumorigenicity
Colonic Cancer Cell Line
Gene: Galnt12 (polypeptide N-acetylgalactosaminyltransferase 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, protein O-linked glycosylation, protein O-linked glycosylation via N-acetyl-galactosamine, protein glycosylation; MF: carbohydrate binding,...
Does Knockout of Tgm3 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Tgm3
protein/peptide distribution
myoblast cell line
Gene: Tgm3 (transglutaminase 3, E polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: epidermis development, hair cell differentiation, keratinization, keratinocyte differentiation, peptide cross-linking, skin development; MF: acyltransferase activity, calcium io...
Does Knockout of Vmn1r68 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Vmn1r68
protein/peptide distribution
myoblast cell line
Gene: Vmn1r68 (vomeronasal 1 receptor 68) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor ...
Does Knockout of Atg16l1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Atg16l1
cell proliferation
Mouse kidney carcinoma cell
Gene: Atg16l1 (autophagy related 16 like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, autophagy, axonal transport, corpus callosum development, defense response to virus, dendrite arborization, hippocampus development, macroautophagy, microau...
Does Knockout of Asb10 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Asb10
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Asb10 (ankyrin repeat and SOCS box-containing 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, intracellular signal transduction, protein ubiquitination; CC: cytoplasm, cytosol, nucleus Pathways: Adaptive Immune System, Antigen proces...
Does Knockout of Ube2l3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Ube2l3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ube2l3 (ubiquitin-conjugating enzyme E2L 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell cycle phase transition, cell population proliferation, cellular response to glucocorticoid stimulus, cellular response to steroid hormone stimulus, positive regulation o...
Does Knockout of Lekr1 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Lekr1
protein/peptide distribution
myoblast cell line
Gene: Lekr1 (leucine, glutamate and lysine rich 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: guanyl-nucleotide exchange factor activity, molecular_function Pathways: UniProt: A0A571BF98, B2RVN1, Q3UVB4 Entrez ID: 624866
Does Knockout of Adamtsl1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Adamtsl1
protein/peptide distribution
myoblast cell line
Gene: Adamtsl1 (ADAMTS-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: extracellular matrix, extracellular region Pathways: Metabolism of proteins, O-glycosylation of TSR domain-containing proteins, O-linked glycosylation, Post-translational protein modif...
Does Knockout of Il18rap in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Il18rap
cell proliferation
Mouse kidney carcinoma cell
Gene: Il18rap (interleukin 18 receptor accessory protein) Type: protein-coding Summary: Interleukin-18 (or interferon-gamma inducing factor) is a proinflammatory cytokine that induces cell-mediated immunity following microbial infection. This gene encodes a member of the interleukin-1 receptor family. T...
Does Knockout of Csdc2 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Csdc2
protein/peptide distribution
myoblast cell line
Gene: Csdc2 (cold shock domain containing C2, RNA binding) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA processing, regulation of mRNA stability; MF: RNA binding, mRNA 3'-UTR binding, nucleic acid binding; CC: cytoplasm, nucleus Pathways: UniPro...
Does Knockout of Sobp in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Sobp
protein/peptide accumulation
Mouse cell
Gene: Sobp (sine oculis binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, cochlea development, cognition, inner ear morphogenesis, locomotory behavior, sensory perception of sound; MF: SUMO polymer binding, metal ion binding, zinc ...
Does Knockout of Pabpc1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Pabpc1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Pabpc1 (poly(A) binding protein, cytoplasmic 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CRD-mediated mRNA stabilization, RNA splicing, mRNA processing, negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay, negative...
Does Knockout of Chfr in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Chfr
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Chfr (checkpoint with forkhead and ring finger domains) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, meiotic spindle checkpoint signaling, mitotic G2/M transition checkpoint, mitotic cell cycle, positive regulation of proteasomal ubiquitin-dependen...
Does Knockout of Dcaf7 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Dcaf7
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Dcaf7 (DDB1 and CUL4 associated factor 7) Type: protein-coding Summary: No summary available. Gene Ontology: CC: Cul4-RING E3 ubiquitin ligase complex, cytoplasm, cytosol, nuclear body, nuclear matrix, nucleoplasm, nucleus, protein-containing complex Pathways: Metabolism of prote...
Does Knockout of Tbx4 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Tbx4
protein/peptide accumulation
Embryonic Cell Line
Gene: Tbx4 (T-box 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, cell fate specification, developmental process, embryonic hindlimb morphogenesis, embryonic limb morphogenesis, embryonic lung development, limb morphogenesis, lung development, morphogenes...
Does Knockout of Samt4 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Samt4
protein/peptide distribution
myoblast cell line
Gene: Samt4 (spermatogenesis associated multipass transmembrane protein 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bicellular tight junction assembly, cell adhesion; MF: molecular_function, structural molecule activity; CC: anchoring junction, bicellular tight jun...
Does Knockout of Crem in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Crem
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Crem (cAMP responsive element modulator) Type: protein-coding Summary: This gene encodes a basic-leucine zipper domain-containing protein that localizes to gene promoters, where it binds to the cyclic AMP response element (CRE). Different protein isoforms encoded by this gene may function as eithe...
Does Knockout of Mob3c in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Mob3c
protein/peptide distribution
Microglial Cell Line
Gene: Mob3c (MOB kinase activator 3C) Type: protein-coding Summary: Predicted to enable protein kinase activator activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm and nucleus. Orthologous to human MOB3C (MOB kinase activator 3C). [provided by Alliance of Geno...
Does Knockout of Ddx42 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Ddx42
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ddx42 (DEAD box helicase 42) Type: protein-coding Summary: No summary available. Gene Ontology: BP: U2-type prespliceosome assembly, intracellular protein localization, regulation of apoptotic process; MF: ATP binding, ATP hydrolysis activity, RNA binding, RNA helicase activity, helicase ...
Does Knockout of Cep78 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Cep78
protein/peptide distribution
myoblast cell line
Gene: Cep78 (centrosomal protein 78) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, cilium organization, flagellated sperm motility, negative regulation of protein ubiquitination, protein localization to centrosome, protein localization to c...
Does Knockout of Card11 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Card11
cell proliferation
Colonic Cancer Cell Line
Gene: Card11 (caspase recruitment domain family, member 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, B cell proliferation, T cell activation, T cell costimulation, TORC1 signaling, canonical NF-kappaB signal transduction, homeostasis of numb...
Does Knockout of Ndufaf3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Ndufaf3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ndufaf3 (NADH:ubiquinone oxidoreductase complex assembly factor 3) Type: protein-coding Summary: Predicted to be involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Is expressed in olfactory epithelium. Human ortholog(s) of this gene implicated in nuclear type...
Does Knockout of Ubald1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Ubald1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ubald1 (UBA-like domain containing 1) Type: protein-coding Summary: Is expressed in central nervous system; embryo; retina; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human UBALD1 (UBA like domain containing 1). [provided by Alliance of Genome Resources, Jul 2025] ...
Does Knockout of Eras in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Eras
protein/peptide accumulation
Embryonic Cell Line
Gene: Eras (ES cell-expressed Ras) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Ras protein signal transduction, signal transduction; MF: G protein activity, GDP binding, GTP binding, GTPase activity, hydrolase activity, nucleotide binding; CC: membrane, plasma membran...
Does Knockout of Tdpoz4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Tdpoz4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tdpoz4 (TD and POZ domain containing 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, protein catabolic process, protein polyubiquitination, regulation of proteolysis; MF: identical protein binding...
Does Knockout of Nle1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Nle1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Nle1 (notchless homolog 1) Type: protein-coding Summary: Acts upstream of or within several processes, including chordate embryonic development; hematopoietic stem cell homeostasis; and positive regulation of canonical Wnt signaling pathway. Located in nucleolus. Is expressed in several structures...
Does Knockout of Pcna in Lymphoma Cell Line causally result in response to chemicals?
1
1,536
Knockout
Pcna
response to chemicals
Lymphoma Cell Line
Gene: Pcna (proliferating cell nuclear antigen) Type: protein-coding Summary: Enables enzyme binding activity. Involved in mitotic telomere maintenance via semi-conservative replication and replication fork processing. Acts upstream of or within base-excision repair, gap-filling; cellular response to xe...
Does Knockout of Jpt1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Jpt1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Jpt1 (Jupiter microtubule associated homolog 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, cytosol, intercellular bridge, microtubule cytoskeleton, nucleoplasm, nucleus Pathways: UniProt: P97825 Entrez ID: 15374
Does Knockout of Idh1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Idh1
protein/peptide accumulation
Regulatory T cell
Gene: Idh1 (isocitrate dehydrogenase 1 (NADP+), soluble) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 2-oxoglutarate metabolic process, NADP+ metabolic process, NADPH regeneration, female gonad development, glutathione metabolic process, glyoxylate cycle, isocitrate me...
Does Knockout of Gm5591 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Gm5591
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gm5591 (predicted gene 5591) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8CDK1 Entrez ID: 434171
Does Knockout of Fstl3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Fstl3
cell proliferation
Mouse kidney carcinoma cell
Gene: Fstl3 (follistatin-like 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, hematopoietic progenitor cell differentiation, negative regulation of BMP signaling pathway, negative regulation of activin receptor signaling pathway, negative regulati...
Does Knockout of Tas1r3 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Tas1r3
autophagy
Embryonic Fibroblast Cell Line
Gene: Tas1r3 (taste receptor, type 1, member 3) Type: protein-coding Summary: Predicted to enable G protein-coupled receptor activity and taste receptor activity. Predicted to contribute to sweet taste receptor activity. Acts upstream of or within sensory perception of sweet taste. Predicted to be locat...
Does Knockout of Vezf1 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Vezf1
protein/peptide accumulation
Mouse cell
Gene: Vezf1 (vascular endothelial zinc finger 1) Type: protein-coding Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within angiogenesi...
Does Knockout of Rps6kb1 in Melanoma Cell Line causally result in tumorigenicity?
1
615
Knockout
Rps6kb1
tumorigenicity
Melanoma Cell Line
Gene: Rps6kb1 (ribosomal protein S6 kinase, polypeptide 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G1/S transition of mitotic cell cycle, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, TOR signaling, TORC1 signaling, TORC2 signaling, apop...
Does Knockout of Sh3rf2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Sh3rf2
cell proliferation
Colonic Cancer Cell Line
Gene: Sh3rf2 (SH3 domain containing ring finger 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of JNK cascade, negative regulation of apoptotic process, negative regulation of protein ubiquitination, positive regulation of JNK cascade, positive reg...
Does Knockout of Dkc1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
578
Knockout
Dkc1
cell proliferation
Embryonic Stem Cell Line
Gene: Dkc1 (dyskeratosis congenita 1, dyskerin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA modification, RNA processing, box H/ACA sno(s)RNA 3'-end processing, box H/ACA sno(s)RNA metabolic process, enzyme-directed rRNA pseudouridine synthesis, mRNA pseudouridine...
Does Knockout of H2-Q7 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
H2-Q7
cell cycle progression
breast epithelium
Gene: H2-Q7 (histocompatibility 2, Q region locus 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent, antigen processing and presentation of endogenous peptid...
Does Knockout of Axin2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Axin2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Axin2 (axin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, aortic valve morphogenesis, bone mineralization, canonical Wnt signaling pathway, cell development, cellular response to dexamethasone stimulus, chondrocyte differentiation involve...
Does Knockout of Tmcc3 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,440
Knockout
Tmcc3
protein/peptide accumulation
Embryonic Cell Line
Gene: Tmcc3 (transmembrane and coiled coil domains 3) Type: protein-coding Summary: Predicted to enable 14-3-3 protein binding activity and identical protein binding activity. Predicted to be located in endoplasmic reticulum. Predicted to be active in endomembrane system. Is expressed in several structu...
Does Knockout of Parl in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,287
Knockout
Parl
cell proliferation
Mouse kidney carcinoma cell
Gene: Parl (presenilin associated, rhomboid-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: membrane protein proteolysis, mitochondrial fusion, negative regulation of intrinsic apoptotic signaling pathway, negative regulation of release of cytochrome c from mitochon...
Does Knockout of Acsl4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Acsl4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Acsl4 (acyl-CoA synthetase long-chain family member 4) Type: protein-coding Summary: Enables long-chain fatty acid-CoA ligase activity. Involved in fatty acid derivative biosynthetic process and fatty acid metabolic process. Acts upstream of or within embryonic process involved in female pregnancy...
Does Knockout of Epn1 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Epn1
protein/peptide distribution
myoblast cell line
Gene: Epn1 (epsin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, clathrin coat assembly, embryonic organ development, endocytosis, female pregnancy, in utero embryonic development, membrane fission, negative regulation of sprouting angiogenesi...
Does Knockout of Ciart in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Ciart
cell proliferation
Embryonic Stem Cell Line
Gene: Ciart (circadian associated repressor of transcription) Type: protein-coding Summary: No summary available. Gene Ontology: BP: circadian regulation of gene expression, locomotor rhythm, negative regulation of DNA-templated transcription, rhythmic process; MF: E-box binding, RNA polymerase...
Does Knockout of Il20 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Il20
protein/peptide distribution
myoblast cell line
Gene: Il20 (interleukin 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: hemopoiesis, immune response, positive regulation of osteoclast differentiation, signal transduction; MF: cytokine activity, interleukin-20 receptor binding, interleukin-22 receptor binding, signa...
Does Knockout of Fxn in Embryonic Stem Cell Line causally result in cell proliferation?
1
578
Knockout
Fxn
cell proliferation
Embryonic Stem Cell Line
Gene: Fxn (frataxin) Type: protein-coding Summary: Predicted to enable several functions, including 2 iron, 2 sulfur cluster binding activity; ferroxidase activity; and iron ion binding activity. Involved in [4Fe-4S] cluster assembly. Acts upstream of or within several processes, including adult walking...
Does Knockout of Tcaim in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Tcaim
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Tcaim (T cell activation inhibitor, mitochondrial) Type: protein-coding Summary: Located in mitochondrion. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and respiratory system. Orthologous to human TCAIM (T cell activation inhi...
Does Knockout of Zfyve26 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Zfyve26
protein/peptide distribution
myoblast cell line
Gene: Zfyve26 (zinc finger, FYVE domain containing 26) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, autophagosome organization, cell division, double-strand break repair via homologous recombination, lysosome organization, mitotic cytok...
Does Knockout of Chmp6 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,287
Knockout
Chmp6
cell proliferation
Mouse kidney carcinoma cell
Gene: Chmp6 (charged multivesicular body protein 6) Type: protein-coding Summary: Predicted to be involved in several processes, including midbody abscission; regulation of protein metabolic process; and vacuolar transport. Predicted to be located in several cellular components, including bounding membr...
Does Knockout of Ube2r2 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Ube2r2
phagocytosis
macrophage
Gene: Ube2r2 (ubiquitin-conjugating enzyme E2R 2) Type: protein-coding Summary: Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in protein K48-linked ubiquitination; protein monoubiquitination; and ubiquitin-dependent protein catabolic process. Orthologous to human UB...
Does Knockout of Ifne in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Ifne
protein/peptide distribution
myoblast cell line
Gene: Ifne (interferon epsilon) Type: protein-coding Summary: Predicted to enable cytokine activity and type I interferon receptor binding activity. Involved in defense response to bacterium and defense response to virus. Predicted to be active in extracellular space. Is expressed in diencephalon floor ...
Does Knockout of Cog7 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Cog7
tumorigenicity
Colonic Cancer Cell Line
Gene: Cog7 (component of oligomeric golgi complex 7) Type: protein-coding Summary: Predicted to be involved in several processes, including Golgi vesicle transport; protein localization to Golgi apparatus; and protein stabilization. Predicted to be located in Golgi apparatus and nucleolus. Predicted to ...
Does Knockout of Polr3k in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Polr3k
cell proliferation
Colonic Cancer Cell Line
Gene: Polr3k (polymerase (RNA) III (DNA directed) polypeptide K) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, defense response to virus, immune system process, innate immune response, termination of RNA polymerase III transcription, transcr...
Does Knockout of Btbd8 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Btbd8
cell proliferation
Regulatory T cell
Gene: Btbd8 (BTB domain containing 8) Type: protein-coding Summary: Involved in synaptic vesicle budding from endosome and synaptic vesicle endocytosis. Is extrinsic component of synaptic vesicle membrane. Is expressed in several structures, including adrenal gland; genitourinary system; liver; nervous ...
Does Knockout of Pop7 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Pop7
cell proliferation
Embryonic Stem Cell Line
Gene: Pop7 (processing of precursor 7, ribonuclease P family, (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA processing, rRNA processing, tRNA 5'-leader removal, tRNA processing; MF: nucleic acid binding, ribonuclease P RNA binding, ribonuclease P ac...
Does Knockout of Srsf2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Srsf2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Srsf2 (serine and arginine-rich splicing factor 2) Type: protein-coding Summary: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM...
Does Knockout of Trpc6 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Trpc6
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Trpc6 (transient receptor potential cation channel, subfamily C, member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion transmembrane transport, calcium ion transport, cellular response to hydrogen peroxide, cellular response to hypoxia, monoatomic io...
Does Knockout of Wrap53 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Wrap53
protein/peptide distribution
myoblast cell line
Gene: Wrap53 (WD repeat containing, antisense to Trp53) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Cajal body organization, DNA damage response, DNA repair, RNA folding, positive regulation of DNA repair, positive regulation of double-strand break repair, positive re...
Does Knockout of Dennd6a in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Dennd6a
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Dennd6a (DENN domain containing 6A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of cell-cell adhesion mediated by cadherin; MF: guanyl-nucleotide exchange factor activity; CC: cytoplasm, endosome, recycling endosome Pathways: Membran...
Does Knockout of Trp53i11 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Trp53i11
cell proliferation
Mouse kidney carcinoma cell
Gene: Trp53i11 (transformation related protein 53 inducible protein 11) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q4QQM4 Entrez ID: 277414
Does Knockout of Rps25 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Rps25
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rps25 (ribosomal protein S25) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, rRNA processing, ribosomal small subunit biogenesis; MF: structural constituent of ribosome; CC: cytoplasm, cytosol, cytosolic ribosome, cytosolic small ribosomal ...
Does Knockout of Slitrk6 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Slitrk6
protein/peptide accumulation
Mouse cell
Gene: Slitrk6 (SLIT and NTRK-like family, member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adult locomotory behavior, auditory behavior, auditory receptor cell morphogenesis, axonogenesis, camera-type eye development, cochlea development, inner ear morphogenesis,...
Does Knockout of Vps13a in Malignant Peripheral Nerve Sheath Tumor (MPNST) cancer cell causally result in cell proliferation?
1
2,182
Knockout
Vps13a
cell proliferation
Malignant Peripheral Nerve Sheath Tumor (MPNST) cancer cell
Gene: Vps13a (vacuolar protein sorting 13A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adult locomotory behavior, autophagy, brain-derived neurotrophic factor receptor signaling pathway, cell morphogenesis, cellular response to osmotic stress, erythrocyte differentia...
Does Knockout of Ncbp1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ncbp1
cell proliferation
Embryonic Stem Cell Line
Gene: Ncbp1 (nuclear cap binding protein subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 7-methylguanosine mRNA capping, RNA catabolic process, RNA metabolic process, RNA splicing, alternative mRNA splicing, via spliceosome, cap-dependent translational initiati...
Does Knockout of Znhit1 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Znhit1
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Znhit1 (zinc finger, HIT domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion homeostasis, chromatin organization, chromatin remodeling, heart process, hematopoietic stem cell homeostasis, intestinal stem cell homeostasis, muscle cell dif...
Does Knockout of Pold1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Pold1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pold1 (polymerase (DNA directed), delta 1, catalytic subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA biosynthetic process, DNA damage response, DNA repair, DNA replication, DNA replication proofreading, DNA synthesis involved in DNA repair, DNA-template...
Does Knockout of Trp53rkb in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Trp53rkb
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Trp53rkb (transformation related protein 53 regulating kinase B) Type: protein-coding Summary: Predicted to enable p53 binding activity and protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation and tRNA threonylcarbamoyladenosine metabolic process. Predicted...
Does Knockout of Parp16 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Parp16
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Parp16 (poly (ADP-ribose) polymerase family, member 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: IRE1-mediated unfolded protein response, cellular response to leukemia inhibitory factor, cytoplasmic translation, endoplasmic reticulum unfolded protein response...
Does Knockout of Tyrp1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Tyrp1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tyrp1 (tyrosinase-related protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acetoacetic acid metabolic process, melanin biosynthetic process, melanin biosynthetic process from tyrosine, melanin metabolic process, melanocyte differentiation, melanosome organ...
Does Knockout of Vmn2r90 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,273
Knockout
Vmn2r90
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Vmn2r90 (vomeronasal 2, receptor 90) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: A0A33...
Does Knockout of Otol1 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Otol1
protein/peptide distribution
myoblast cell line
Gene: Otol1 (otolin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: otolith mineralization, protein homooligomerization; MF: calcium ion binding, metal ion binding, protein binding; CC: collagen trimer, extracellular region Pathways: UniProt: Q4ZJM7 ...
Does Knockout of Bap1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Bap1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Bap1 (Brca1 associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cell population proliferation, chromatin organization, common myeloid progenitor cell proliferation, erythrocyte differentiation, erythrocyte maturation, gene exp...