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Does Knockout of Sptb in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Sptb
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sptb (spectrin beta, erythrocytic) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, actin filament capping, hemopoiesis, modification of postsynaptic actin cytoskeleton, plasma membrane organization, porphyrin-containing compound bios...
Does Knockout of Vmn2r18 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Vmn2r18
cell proliferation
Mouse kidney carcinoma cell
Gene: Vmn2r18 (vomeronasal 2, receptor 18) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: A0A3B...
Does Knockout of Ntm in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Ntm
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ntm (neurotrimin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, negative regulation of glial cell proliferation, negative regulation of neuron projection development, positive regulation of Schwann cell migration, positive regulation of neuron proje...
Does Knockout of Hspd1 in Lymphoma Cell Line causally result in response to chemicals?
1
1,545
Knockout
Hspd1
response to chemicals
Lymphoma Cell Line
Gene: Hspd1 (heat shock protein 1 (chaperonin)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation, B cell proliferation, MyD88-dependent toll-like receptor signaling pathway, T cell activation, adhesion of symbiont to host, apoptotic mitochondrial changes,...
Does Knockout of Gtf2a1l in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Gtf2a1l
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Gtf2a1l (general transcription factor IIA, 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cognition, transcription by RNA polymerase II, transcription initiation at RNA polymerase II promoter; MF: DNA binding, protein binding; CC: cytoplasm, male germ cell ...
Does Knockout of Zfp648 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Zfp648
cell proliferation
Melanoma Cell Line
Gene: Zfp648 (zinc finger protein 648) Type: protein-coding Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RN...
Does Knockout of Vmn2r59 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Vmn2r59
protein/peptide accumulation
Embryonic Cell Line
Gene: Vmn2r59 (vomeronasal 2, receptor 59) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: A0A3B...
Does Knockout of Htr3a in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Htr3a
cell viability
Immortal mouse chromaffin cells
Gene: Htr3a (5-hydroxytryptamine (serotonin) receptor 3A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chemical synaptic transmission, excitatory postsynaptic potential, inorganic cation transmembrane transport, monoatomic ion transmembrane transport, monoatomic ion tr...
Does Knockout of Gnl2 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Gnl2
cell viability
Immortal mouse chromaffin cells
Gene: Gnl2 (guanine nucleotide binding protein nucleolar 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: GTP binding, nucleotide binding; CC: nucleolus, nucleus Pathways: Ribosome biogenesis in eukaryotes - Mus musculus (mouse) UniProt: Q99LH1 ...
Does Knockout of Cyp2d26 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Cyp2d26
protein/peptide distribution
myoblast cell line
Gene: Cyp2d26 (cytochrome P450, family 2, subfamily d, polypeptide 26) Type: protein-coding Summary: No summary available. Gene Ontology: BP: arachidonate metabolic process, response to xenobiotic stimulus, xenobiotic metabolic process; MF: anandamide 11,12 epoxidase activity, anandamide 14,15 ...
Does Knockout of Cyth3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Cyth3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cyth3 (cytohesin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi vesicle transport, establishment of epithelial cell polarity, positive regulation of cell adhesion, regulation of ARF protein signal transduction; MF: guanyl-nucleotide exchange factor activit...
Does Knockout of Klrd1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Klrd1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Klrd1 (killer cell lectin-like receptor, subfamily D, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, immune system process, innate immune response, natural killer cell mediated immunity, negative regulation of T cell mediated cyt...
Does Knockout of Tle4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Tle4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tle4 (transducin-like enhancer of split 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, cellular response to leukemia inhibitory factor, negative regulation of DNA-templated transcription, negative regulation of canonical Wnt signaling path...
Does Knockout of Spata31d1a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Spata31d1a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Spata31d1a (spermatogenesis associated 31 subfamily D, member 1A) Type: protein-coding Summary: Orthologous to several human genes including SPATA31D1 (SPATA31 subfamily D member 1). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: CC: cellular_component, membrane ...
Does Knockout of Gse1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Gse1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gse1 (genetic suppressor element 1, coiled-coil protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, gene expression, in utero embryonic development, placenta development Pathways: UniProt: Q3U3C9 Entrez ID: 382034
Does Knockout of Prelid3b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Prelid3b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Prelid3b (PRELI domain containing 3B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intermembrane lipid transfer, phospholipid transport; CC: mitochondrial intermembrane space, mitochondrion Pathways: UniProt: Q9CYY7 Entrez ID: 66390
Does Knockout of Psmc3ip in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Psmc3ip
protein/peptide accumulation
Embryonic Cell Line
Gene: Psmc3ip (proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA recombination, androgen receptor signaling pathway, estrogen receptor signaling pathway, homologous chromosome pairing at meiosis...
Does Knockout of Dot1l in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Dot1l
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dot1l (DOT1 like histone lysine methyltransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage checkpoint signaling, DNA repair, chromatin organization, gene expression, heterochromatin formation, methylation, positive regulation of cell population pr...
Does Knockout of Cpa1 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Cpa1
protein/peptide distribution
myoblast cell line
Gene: Cpa1 (carboxypeptidase A1, pancreatic) Type: protein-coding Summary: This gene encodes carboxypeptidase A, a zinc-dependent metalloprotease that cleaves peptide bonds at the C-terminus of protein substrates. The encoded preproprotein undergoes proteolytic activation to generate a mature, functiona...
Does Knockout of Ntpcr in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Ntpcr
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Ntpcr (nucleoside-triphosphatase, cancer-related) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, ATP hydrolysis activity, CTPase activity, GTPase activity, hydrolase activity, molecular_function, nucleotide binding, ribonucleoside triphosphate phosphat...
Does Knockout of Slfn1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Slfn1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Slfn1 (schlafen 1) Type: protein-coding Summary: Predicted to enable RNA nuclease activity and ribosome binding activity. Acts upstream of or within negative regulation of G1/S transition of mitotic cell cycle; negative regulation of T cell proliferation; and negative regulation of macromolecule m...
Does Knockout of Zfp93 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Zfp93
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Zfp93 (zinc finger protein 93) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, metal ion binding, zinc ion binding Pathways: Herpes simplex virus 1 infection - Mus musculus (mouse) UniProt: Q61116 Entrez ID: 22755
Does Knockout of Ttll12 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ttll12
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ttll12 (tubulin tyrosine ligase-like family, member 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, immune system process, innate immune response, negative regulation of type I interferon-mediated signaling pathway, regulation of mitotic ...
Does Knockout of Timeless in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Timeless
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Timeless (timeless circadian clock 1) Type: protein-coding Summary: The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The enco...
Does Knockout of Siae in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Siae
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Siae (sialic acid acetylesterase) Type: protein-coding Summary: Predicted to enable sialate O-acetylesterase activity. Predicted to be involved in carbohydrate metabolic process and regulation of immune system process. Located in lysosome. Is expressed in several structures, including abdominal fa...
Does Knockout of Copb2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Copb2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Copb2 (COPI coat complex subunit beta 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endoplasmic reticulum to Golgi vesicle-mediated transport, intra-Golgi vesicle-mediated transport, intracellular protein transport, protein transport, retrograde vesicle-mediate...
Does Knockout of Ggt7 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Ggt7
response to chemicals
Pancreatic Cancer Cell Line
Gene: Ggt7 (gamma-glutamyltransferase 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glutathione biosynthetic process, glutathione catabolic process, glutathione metabolic process, negative regulation of response to oxidative stress; MF: acyltransferase activity, glut...
Does Knockout of Zfp831 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Zfp831
cell proliferation
Colonic Cancer Cell Line
Gene: Zfp831 (zinc finger protein 831) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, molecular_function, zinc ion binding Pathways: UniProt: A2ADM8 Entrez ID: 100043757
Does Knockout of Bcs1l in Embryonic Stem Cell Line causally result in cell proliferation?
1
578
Knockout
Bcs1l
cell proliferation
Embryonic Stem Cell Line
Gene: Bcs1l (BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone) Type: protein-coding Summary: The protein encoded by this gene is a chaperone protein that is involved in the assembly of complex III (CIII), one of the five protein complexes of the mitochondrial respiratory chain, and is ne...
Does Knockout of Sec61a1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Sec61a1
cell proliferation
Embryonic Stem Cell Line
Gene: Sec61a1 (SEC61 translocon subunit alpha 1) Type: protein-coding Summary: Enables ribosome binding activity and transmembrane transporter activity. Involved in pronephric nephron development. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of Sec61 translocon complex...
Does Knockout of Letm1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Letm1
cell proliferation
Embryonic Stem Cell Line
Gene: Letm1 (leucine zipper-EF-hand containing transmembrane protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium export from the mitochondrion, calcium ion transport, cristae formation, inner mitochondrial membrane organization, mitochondrial calcium ion ho...
Does Knockout of Defa22 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Defa22
protein/peptide accumulation
Mouse cell
Gene: Defa22 (defensin, alpha, 22) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, defense response, defense response to Gram-negative bacterium, defense response to G...
Does Knockout of Nhp2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Nhp2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nhp2 (NHP2 ribonucleoprotein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: rRNA processing, rRNA pseudouridine synthesis, ribosome biogenesis, snRNA pseudouridine synthesis, snoRNA guided rRNA pseudouridine synthesis, telomere maintenance via telomerase; MF: RNA ...
Does Knockout of Papola in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Papola
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Papola (poly (A) polymerase alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA 3'-end processing, co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, cytosolic mRNA polyadenylation, mRNA 3'-end processing, mRNA processing; MF: AT...
Does Knockout of Rps26 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Rps26
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rps26 (ribosomal protein S26) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, negative regulation of RNA splicing, translation, translation at postsynapse, translation at presynapse; MF: mRNA binding, structural constituent of ribosome; CC: ...
Does Knockout of Taf1a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Taf1a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Taf1a (TATA-box binding protein associated factor, RNA polymerase I, A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: transcription by RNA polymerase I; MF: DNA binding, protein binding; CC: RNA polymerase I transcription regulator complex, RNA polymerase transcri...
Does Knockout of Abcc1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Abcc1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Abcc1 (ATP-binding cassette, sub-family C member 1) Type: protein-coding Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC...
Does Knockout of Pigf in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
1
2,172
Knockout
Pigf
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Pigf (phosphatidylinositol glycan anchor biosynthesis, class F) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GPI anchor biosynthetic process; CC: endoplasmic reticulum, endoplasmic reticulum membrane, membrane Pathways: Glycosylphosphatidylinositol (GPI)...
Does Knockout of Mapre2 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Mapre2
cell proliferation
Regulatory T cell
Gene: Mapre2 (microtubule-associated protein, RP/EB family, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, positive regulation of ARF protein signal transduction, positive regulation of focal adhesion disassembly, positive regulation of keratinoc...
Does Knockout of Sfpq in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Sfpq
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sfpq (splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, RNA splicing, activation of innate immune response, alternative mRNA splicing, via splice...
Does Knockout of Etv2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Etv2
cell proliferation
Mouse kidney carcinoma cell
Gene: Etv2 (ets variant 2) Type: protein-coding Summary: Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstre...
Does Knockout of Bglap2 in Colonic Cancer Cell Line causally result in cell proliferation?
1
2,176
Knockout
Bglap2
cell proliferation
Colonic Cancer Cell Line
Gene: Bglap2 (bone gamma-carboxyglutamate protein 2) Type: protein-coding Summary: This gene encodes a preproprotein that is proteolytically processed to generate a mature protein product. This protein product is a hormone that is secreted by osteoblasts and may function in bone remodeling and energy me...
Does Knockout of Rflna in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Rflna
cell proliferation
Mouse kidney carcinoma cell
Gene: Rflna (refilin A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament bundle organization, negative regulation of bone mineralization involved in bone maturation, negative regulation of chondrocyte development, regulation of chondrocyte development, skele...
Does Knockout of Commd6 in macrophage causally result in phagocytosis?
1
1,888
Knockout
Commd6
phagocytosis
macrophage
Gene: Commd6 (COMM domain containing 6) Type: protein-coding Summary: No summary available. Gene Ontology: MF: NF-kappaB binding; CC: cellular_component, cytoplasm, nucleus Pathways: Metabolism of proteins, Neddylation, Post-translational protein modification UniProt: Q3V4B5 ...
Does Knockout of Slc38a2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Slc38a2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Slc38a2 (solute carrier family 38, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-glutamine import across plasma membrane, L-proline import across plasma membrane, L-serine import across plasma membrane, L-serine transport, acidic amino acid transport, ...
Does Knockout of Impa2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Impa2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Impa2 (inositol monophosphatase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: inositol biosynthetic process, inositol metabolic process, phosphatidylinositol phosphate biosynthetic process, response to lithium ion, signal transduction; MF: glucose-1-phosphatase...
Does Knockout of Ssu72 in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Ssu72
cell proliferation
Embryonic Stem Cell Line
Gene: Ssu72 (Ssu72 RNA polymerase II CTD phosphatase homolog (yeast)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, mRNA 3'-end processing, mRNA processing, regulation of transcription by R...
Does Knockout of Timm8a1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Timm8a1
cell proliferation
Embryonic Stem Cell Line
Gene: Timm8a1 (translocase of inner mitochondrial membrane 8A1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein insertion into mitochondrial inner membrane, protein targeting to mitochondrion, protein transport; MF: identical protein binding, metal ion binding, zi...
Does Knockout of Atp6ap1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Atp6ap1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Atp6ap1 (ATPase, H+ transporting, lysosomal accessory protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to increased oxygen levels, endosome to plasma membrane protein transport, intracellular iron ion homeostasis, monoatomic ion transport...
Does Knockout of Spx in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Spx
protein/peptide distribution
myoblast cell line
Gene: Spx (spexin hormone) Type: protein-coding Summary: No summary available. Gene Ontology: BP: long-chain fatty acid import into cell, negative regulation of appetite, negative regulation of heart rate, negative regulation of renal sodium excretion, positive regulation of gastro-intestinal s...
Does Knockout of Nccrp1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Nccrp1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Nccrp1 (non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, glycoprotein catabolic process, positive regulation of ...
Does Knockout of Zswim7 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Zswim7
autophagy
Embryonic Fibroblast Cell Line
Gene: Zswim7 (zinc finger SWIM-type containing 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, double-strand break repair via homologous recombination, protein stabilization; MF: metal ion binding, zinc ion binding; C...
Does Knockout of Ncor2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Ncor2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ncor2 (nuclear receptor co-repressor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell proliferation in forebrain, epidermis development, establishment of skin barrier, forebrain development, gene expression, glucose homeostasis, heart morphogenesis, in utero ...
Does Knockout of Kif17 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Kif17
protein/peptide distribution
Microglial Cell Line
Gene: Kif17 (kinesin family member 17) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterograde dendritic transport of neurotransmitter receptor complex, cell projection organization, intraciliary transport, microtubule-based movement, microtubule-based process, protei...
Does Knockout of Gpr174 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Gpr174
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gpr174 (G protein-coupled receptor 174) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, T cell homeostasis, adenylate cyclase-activating G protein-coupled receptor signaling pathway, negative regulation of interleukin-2 ...
Does Knockout of Fam162b in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Fam162b
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Fam162b (family with sequence similarity 162, member B) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q9CX19 Entrez ID: 77296
Does Knockout of Ascc2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Ascc2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Ascc2 (activating signal cointegrator 1 complex subunit 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, regulation of DNA-templated transcription, rescue of stalled ribosome, ribosome disassembly, ribosome-associated ubiquitin-dep...
Does Knockout of Pinlyp in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Pinlyp
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Pinlyp (phospholipase A2 inhibitor and LY6/PLAUR domain containing) Type: protein-coding Summary: Predicted to enable phospholipase inhibitor activity. Predicted to be located in extracellular region. Orthologous to human PINLYP (phospholipase A2 inhibitor and LY6/PLAUR domain containing). [provid...
Does Knockout of Sod3 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Sod3
tumorigenicity
Colonic Cancer Cell Line
Gene: Sod3 (superoxide dismutase 3, extracellular) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blood vessel diameter maintenance, removal of superoxide radicals, response to copper ion, response to hypoxia, superoxide metabolic process; MF: antioxidant activity, coppe...
Does Knockout of Traf3ip2 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Traf3ip2
protein/peptide distribution
myoblast cell line
Gene: Traf3ip2 (TRAF3 interacting protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell affinity maturation, B cell apoptotic process, B cell homeostasis, B cell mediated immunity, CD40 signaling pathway, T cell activation, T cell differentiation, T-helper 17 ...
Does Knockout of Hsbp1l1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Hsbp1l1
protein/peptide accumulation
Embryonic Cell Line
Gene: Hsbp1l1 (heat shock factor binding protein 1-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular heat acclimation, negative regulation of DNA-templated transcription; MF: molecular_function, transcription corepressor activity; CC: cytosol, nucleus ...
Does Knockout of Slc25a17 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Slc25a17
tumorigenicity
Colonic Cancer Cell Line
Gene: Slc25a17 (solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ADP transport, AMP transport, ATP transport, FAD transmembrane transport, NAD transmembrane transport, NAD transport,...
Does Knockout of Esp6 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Esp6
protein/peptide distribution
myoblast cell line
Gene: Esp6 (exocrine gland secreted peptide 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, signal transduction; MF: pheromone activity; CC: extracellular space, membrane Pathways: UniProt: A0A3B2WD20, A8R0U0 Entrez ID: 43...
Does Knockout of Wdr62 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,440
Knockout
Wdr62
protein/peptide accumulation
Embryonic Cell Line
Gene: Wdr62 (WD repeat domain 62) Type: protein-coding Summary: No summary available. Gene Ontology: BP: centriole replication, cerebral cortex development, mitotic spindle organization, neurogenesis, neuronal stem cell population maintenance, positive regulation of neuroblast proliferation, po...
Does Knockout of Nav1 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Nav1
cell proliferation
Melanoma Cell Line
Gene: Nav1 (neuron navigator 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, microtubule bundle formation, nervous system development, neurogenesis, neuron migration; CC: axon initial segment, cytoplasm, cytoskeleton, microtubule, microtubule cyto...
Does Knockout of Grcc10 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Grcc10
cell proliferation
Embryonic Stem Cell Line
Gene: Grcc10 (gene rich cluster, C10 gene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: camera-type eye morphogenesis, cognition, corpus callosum morphogenesis, post-embryonic development, psychomotor behavior, regulation of skeletal muscle contraction, third ventricle...
Does Knockout of Supv3l1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Supv3l1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Supv3l1 (suppressor of var1, 3-like 1 (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA recombination, RNA catabolic process, mitochondrial RNA 3'-end processing, mitochondrial RNA surveillance, mitochondrial mRNA catabolic process, mitochondrial ...
Does Knockout of Kctd5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Kctd5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Kctd5 (potassium channel tetramerisation domain containing 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, protein homooligomerization; MF: cullin family protein binding, identical protein binding...
Does Knockout of Ddx49 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Ddx49
cell proliferation
Colonic Cancer Cell Line
Gene: Ddx49 (DEAD box helicase 49) Type: protein-coding Summary: Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be involved in positive regulation of cell growth; rRNA processing; and regulation of rRNA stability. P...
Does Knockout of Junb in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Junb
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Junb (jun B proto-oncogene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to calcium ion, decidualization, embryonic process involved in female pregnancy, in utero embryonic development, labyrinthine layer blood vessel development, osteoblast dif...
Does Knockout of Acss2 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Acss2
protein/peptide distribution
myoblast cell line
Gene: Acss2 (acyl-CoA synthetase short-chain family member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acetate biosynthetic process, acetyl-CoA biosynthetic process, lipid biosynthetic process, lipid metabolic process, long-term memory, positive regulation of DNA-t...
Does Knockout of Tax1bp3 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Tax1bp3
cell proliferation
Mouse kidney carcinoma cell
Gene: Tax1bp3 (Tax1 (human T cell leukemia virus type I) binding protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rho protein signal transduction, Wnt signaling pathway, negative regulation of Wnt signaling pathway, negative regulation of cell population prolife...
Does Knockout of Zfp330 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Zfp330
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Zfp330 (zinc finger protein 330) Type: protein-coding Summary: Predicted to enable zinc ion binding activity. Predicted to be located in chromosome, centromeric region; midbody; and nuclear lumen. Predicted to be active in nucleus. Is expressed in central nervous system and genitourinary system. O...
Does Knockout of Cdc73 in Regulatory T cell causally result in protein/peptide accumulation?
1
1,482
Knockout
Cdc73
protein/peptide accumulation
Regulatory T cell
Gene: Cdc73 (cell division cycle 73, Paf1/RNA polymerase II complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, cellular response to lipopolysaccharide, endodermal cell fate commitment, mRNA 3'-end processing, negative regulation of G...
Does Knockout of Cyp4a12b in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Cyp4a12b
protein/peptide distribution
myoblast cell line
Gene: Cyp4a12b (cytochrome P450, family 4, subfamily a, polypeptide 12B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: arachidonate metabolic process, fatty acid metabolic process, icosanoid biosynthetic process, kidney development, lauric acid metabolic process, linole...
Does Knockout of Cep72 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Cep72
protein/peptide distribution
myoblast cell line
Gene: Cep72 (centrosomal protein 72) Type: protein-coding Summary: No summary available. Gene Ontology: BP: centriole replication, gamma-tubulin complex localization, regulation of protein localization to centrosome, spindle organization; CC: centriolar satellite, centrosome, ciliary basal body...
Does Knockout of Fpr-rs3 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Fpr-rs3
protein/peptide accumulation
Embryonic Cell Line
Gene: Fpr-rs3 (formyl peptide receptor, related sequence 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, chemotaxis, complement receptor mediated signaling pathway, inflammatory response, phospholipase C-activating G protei...
Does Knockout of Farsa in Embryonic Stem Cell Line causally result in cell proliferation?
1
579
Knockout
Farsa
cell proliferation
Embryonic Stem Cell Line
Gene: Farsa (phenylalanyl-tRNA synthetase, alpha subunit) Type: protein-coding Summary: Predicted to enable magnesium ion binding activity and phenylalanine-tRNA ligase activity. Predicted to be involved in phenylalanyl-tRNA aminoacylation and protein heterotetramerization. Predicted to be part of pheny...
Does Knockout of Invs in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Invs
cell viability
Immortal mouse chromaffin cells
Gene: Invs (inversin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, animal organ development, embryonic heart tube left/right pattern formation, epithelial cilium movement involved in determination of left/right asymmetry, kidney development, nega...
Does Knockout of Defb18 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Defb18
cell proliferation
Mouse kidney carcinoma cell
Gene: Defb18 (defensin beta 18) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, defense response, defense response to bacterium, innate immune response; CC: cellular_component, extracellular region Pathways: Antimicrobial peptides, Beta defens...
Does Knockout of Bicc1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Bicc1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Bicc1 (BicC family RNA binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: determination of left/right symmetry, heart development, kidney development, mRNA catabolic process, negative regulation of canonical Wnt signaling pathway; MF: RNA binding, nu...
Does Knockout of C1qtnf3 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
C1qtnf3
protein/peptide distribution
Microglial Cell Line
Gene: C1qtnf3 (C1q and tumor necrosis factor related protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chemical homeostasis, glucose homeostasis, intracellular triglyceride homeostasis, negative regulation of gene expression, negative regulation of gluconeogenesi...
Does Knockout of Snupn in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Snupn
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Snupn (snurportin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA import into nucleus, cytoskeleton organization, protein complex oligomerization, protein import into nucleus, protein tetramerization, snRNA import into nucleus; MF: RNA binding, RNA cap bindin...
Does Knockout of Dap3 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Dap3
protein/peptide distribution
myoblast cell line
Gene: Dap3 (death associated protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic mitochondrial changes, apoptotic process, mitochondrial translation; MF: GTPase activity, hydrolase activity, structural constituent of ribosome; CC: mitochondrial inner memb...
Does Knockout of Kcnk5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Kcnk5
cell proliferation
Mouse kidney carcinoma cell
Gene: Kcnk5 (potassium channel, subfamily K, member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion export across plasma membrane, potassium ion import across plasma membrane, potassium ion...
Does Knockout of Tnxb in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Tnxb
cell proliferation
Embryonic Stem Cell Line
Gene: Tnxb (tenascin XB) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell-cell adhesion, cell-matrix adhesion, collagen fibril organization, collagen metabolic process, elastic fiber assembly, extracellular matrix organization, fatty acid metabolic proc...
Does Knockout of Scfd1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Scfd1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Scfd1 (Sec1 family domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endoplasmic reticulum to Golgi vesicle-mediated transport, intracellular protein transport, negative regulation of autophagosome assembly, post-Golgi vesicle-mediated transport, ...
Does Knockout of Cdkn1a in Melanoma Cell Line causally result in cell proliferation?
1
2,491
Knockout
Cdkn1a
cell proliferation
Melanoma Cell Line
Gene: Cdkn1a (cyclin dependent kinase inhibitor 1A) Type: protein-coding Summary: This gene encodes a potent cyclin-dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin-cyclin-dependent kinase2 or cyclin-dependent kinase4 complexes, and thus functions as a regulat...
Does Knockout of Tas2r110 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Tas2r110
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tas2r110 (taste receptor, type 2, member 110) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of bitter taste, detection of chemical stimulus involved in sens...
Does Knockout of Mcm8 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Mcm8
cell cycle progression
breast epithelium
Gene: Mcm8 (minichromosome maintenance 8 homologous recombination repair factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, double-strand break repair via homologous recombination, female gamete generation, male gamet...
Does Knockout of Heatr1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Heatr1
cell proliferation
Melanoma Cell Line
Gene: Heatr1 (HEAT repeat containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), neural precursor cell proliferation, positive regulation of rRNA processing, positive regulati...
Does Knockout of Tamm41 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Tamm41
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Tamm41 (TAM41 mitochondrial translocator assembly and maintenance homolog) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CDP-diacylglycerol biosynthetic process, cardiolipin biosynthetic process, lipid metabolic process, phospholipid biosynthetic process; MF: nucl...
Does Knockout of Bsx in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Bsx
protein/peptide distribution
myoblast cell line
Gene: Bsx (brain specific homeobox) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, cell differentiation, eating behavior, locomotory behavior, mammary gland involution, positive regulation of transcription by RNA polymerase II, regulation of DNA-templa...
Does Knockout of Defb47 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Defb47
phagocytosis
macrophage
Gene: Defb47 (defensin beta 47) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell chemotaxis, defense response to bacterium, positive chemotaxis; MF: CCR6 chemokine receptor binding, chemoattractant activity; CC: cytosol, extracellular region, extracellular space ...
Does Knockout of Ifrd2 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Ifrd2
protein/peptide accumulation
Regulatory T cell
Gene: Ifrd2 (interferon-related developmental regulator 2) Type: protein-coding Summary: Predicted to enable ribosome binding activity and translation repressor activity. Acts upstream of or within several processes, including Wnt signaling pathway; adipose tissue development; and fat cell differentiati...
Does Knockout of Agpat2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Agpat2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Agpat2 (1-acylglycerol-3-phosphate O-acyltransferase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CDP-diacylglycerol biosynthetic process, epidermis development, lipid metabolic process, phosphatidic acid biosynthetic process, phospholipid biosynthetic process...
Does Knockout of Epb42 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Epb42
protein/peptide accumulation
Embryonic Cell Line
Gene: Epb42 (erythrocyte membrane protein band 4.2) Type: protein-coding Summary: The protein encoded by this gene is the key component of a macromolecular complex involved in the structure of erythrocytes. [provided by RefSeq, Aug 2015]. Gene Ontology: BP: cell morphogenesis, erythrocyte matur...
Does Knockout of Prokr1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Prokr1
cell proliferation
Mouse kidney carcinoma cell
Gene: Prokr1 (prokineticin receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, cellular response to hormone stimulus, circadian rhythm, coronary vasculature development, negative regulation of apoptotic process, neurop...
Does Knockout of Mrps18a in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Mrps18a
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Mrps18a (mitochondrial ribosomal protein S18A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: small ribosomal subunit rRNA binding, structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large...
Does Knockout of Spast in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Spast
response to chemicals
Pancreatic Cancer Cell Line
Gene: Spast (spastin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterograde axonal transport, axonal transport of mitochondrion, axonogenesis, cell differentiation, cell division, central nervous system neuron axonogenesis, cytokinetic process, endoplasmic reticulum...