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Does Knockout of Strn in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Strn
protein/peptide distribution
myoblast cell line
Gene: Strn (striatin, calmodulin binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, dendrite development, locomotory behavior, negative regulation of cell population proliferation, regulation of modification of postsynaptic structure, ...
Does Knockout of Ndrg4 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Ndrg4
protein/peptide distribution
Microglial Cell Line
Gene: Ndrg4 (N-myc downstream regulated gene 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell migration involved in heart development, negative regulation of platelet-derived growth factor receptor signaling pathway, negative regulation of smooth muscle cell migrat...
Does Knockout of Polr3b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Polr3b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Polr3b (polymerase (RNA) III (DNA directed) polypeptide B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, defense response to virus, immune system process, innate immune response, positive regulation of innate immune response, positive ...
Does Knockout of Gm5148 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Gm5148
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gm5148 (predicted gene 5148) Type: protein-coding Summary: predicted gene 5148 Gene Ontology: Pathways: UniProt: Q8BGG2 Entrez ID: 381438
Does Knockout of Nsmce2 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Nsmce2
cell viability
Immortal mouse chromaffin cells
Gene: Nsmce2 (NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, cell division, cellular senescence, double-strand break repair via homologous recombination, positive regul...
Does Knockout of 2510039O18Rik in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
2510039O18Rik
cell proliferation
Colonic Cancer Cell Line
Gene: 2510039O18Rik (RIKEN cDNA 2510039O18 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q91X21 Entrez ID: 77034
Does Knockout of Notch1 in Pancreatic Cell Line causally result in protein/peptide accumulation?
0
2,197
Knockout
Notch1
protein/peptide accumulation
Pancreatic Cell Line
Gene: Notch1 (notch 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation, T-helper 17 type immune response, angiogenesis, animal organ regeneration, ao...
Does Knockout of Cilp in Microglial Cell Line causally result in protein/peptide distribution?
1
1,585
Knockout
Cilp
protein/peptide distribution
Microglial Cell Line
Gene: Cilp (cartilage intermediate layer protein, nucleotide pyrophosphohydrolase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of SMAD protein signal transduction, negative regulation of gene expression, negative regulation of insulin-like growth f...
Does Knockout of Tor1aip1 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Tor1aip1
protein/peptide distribution
myoblast cell line
Gene: Tor1aip1 (torsin A interacting protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nuclear membrane organization, positive regulation of ATP-dependent activity, protein localization to nuclear envelope; MF: ATPase activator activity, ATPase binding, cytoskele...
Does Knockout of Thbs4 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Thbs4
protein/peptide accumulation
Embryonic Cell Line
Gene: Thbs4 (thrombospondin 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: behavioral response to pain, cell adhesion, endothelial cell-cell adhesion, myoblast migration, negative regulation of angiogenesis, nervous system development, neuron projection morphogenesis,...
Does Knockout of Psmg4 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Psmg4
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Psmg4 (proteasome (prosome, macropain) assembly chaperone 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, proteasome assembly; MF: molecular_function, protein binding, protein-containing complex binding; CC: cytosol, protein-containing complex...
Does Knockout of Cdk13 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,271
Knockout
Cdk13
cell proliferation
Mouse kidney carcinoma cell
Gene: Cdk13 (cyclin dependent kinase 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, alternative mRNA splicing, via spliceosome, hemopoiesis, mRNA processing, negative regulation of stem cell differentiation, positive regulation of transcription by RNA p...
Does Knockout of Mtfp1 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Mtfp1
cell viability
Immortal mouse chromaffin cells
Gene: Mtfp1 (mitochondrial fission process 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, mitochondrial fission, mitochondrial membrane organization, mitochondrion organization; CC: membrane, mitochondrial inner membrane, mitochondrion Path...
Does Knockout of Cetn1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Cetn1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Cetn1 (centrin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, cellular response to heat, centriole replication, microtubule cytoskeleton organization; MF: G-protein beta/gamma-subunit complex binding, calcium ion binding, heterotrimeric G-protein ...
Does Knockout of Cdca5 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Cdca5
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cdca5 (cell division cycle associated 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, double-strand break repair, mitotic sister chromatid cohesion; MF: protein binding, protein-containing complex binding; CC: chromatin, chromosome, cytoplasm, nucl...
Does Knockout of Tstd2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Tstd2
cell proliferation
Colonic Cancer Cell Line
Gene: Tstd2 (thiosulfate sulfurtransferase (rhodanese)-like domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q3U269 Entrez ID: 272027
Does Knockout of Ms4a18 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Ms4a18
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ms4a18 (membrane-spanning 4-domains, subfamily A, member 18) Type: protein-coding Summary: Predicted to be involved in cell surface receptor signaling pathway. Predicted to be active in plasma membrane. Orthologous to human MS4A18 (membrane spanning 4-domains A18). [provided by Alliance of Genome ...
Does Knockout of Mex3b in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Mex3b
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Mex3b (mex3 RNA binding family member B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: establishment of localization in cell, positive regulation of cell-cell adhesion, positive regulation of phagocytosis, protein localization to cell cortex; MF: GTPase activating...
Does Knockout of Lmo7 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Lmo7
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Lmo7 (LIM domain only 7) Type: protein-coding Summary: Predicted to enable actinin binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in several cellular components, including adherens junction; apical plasma membrane; a...
Does Knockout of Arhgef7 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Arhgef7
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Arhgef7 (Rho guanine nucleotide exchange factor) Type: protein-coding Summary: Enables guanyl-nucleotide exchange factor activity and protein kinase binding activity. Involved in lamellipodium assembly. Acts upstream of or within hematopoietic progenitor cell differentiation; positive regulation o...
Does Knockout of Thoc1 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Thoc1
protein/peptide accumulation
Embryonic Cell Line
Gene: Thoc1 (THO complex 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, apoptotic process, mRNA export from nucleus, mRNA processing, mRNA transport, regulation of apoptotic process, signal transduction; MF: DNA binding, RNA binding, identical protein bi...
Does Knockout of Foxl1 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Foxl1
response to virus
Embryonic Fibroblast Cell Line
Gene: Foxl1 (forkhead box L1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Peyer's patch morphogenesis, anatomical structure morphogenesis, cell differentiation, heart development, proteoglycan biosynthetic process, regulation of DNA-templated transcription, regulation...
Does Knockout of Gm3336 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Gm3336
cell proliferation
Melanoma Cell Line
Gene: Gm3336 (predicted gene 3336) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: A0A1D5RMG6, J3QMQ6 Entrez ID: 100502950
Does Knockout of Mcm5 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Mcm5
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Mcm5 (minichromosome maintenance complex component 5) Type: protein-coding Summary: The protein encoded by this gene is a member of the oligameric minichromosome maintenance protein complex. During DNA replication, the complex loads onto chromatin in early G1 and is converted into an active replic...
Does Knockout of Csnk2b in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Csnk2b
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Csnk2b (casein kinase 2, beta polypeptide) Type: protein-coding Summary: This gene encodes the beta subunit of the casein kinase 2 enzyme, which is a heterotetramer comprised of alpha and/or alpha-prime catalytic subunits and two regulatory beta subunits. Casein kinase 2 is involved in the regulat...
Does Knockout of Zbtb8a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Zbtb8a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Zbtb8a (zinc finger and BTB domain containing 8a) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, negative regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcript...
Does Knockout of Nfx1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Nfx1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Nfx1 (nuclear transcription factor, X-box binding 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of MHC class II biosynthetic process, negative regulation of transcription by RNA polymerase II, protein autoubiquitination; MF: DNA binding, DNA...
Does Knockout of Plcb1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Plcb1
protein/peptide distribution
myoblast cell line
Gene: Plcb1 (phospholipase C, beta 1) Type: protein-coding Summary: Enables lamin binding activity and phosphatidylinositol-4,5-bisphosphate phospholipase C activity. Involved in several processes, including positive regulation of cell cycle process; regulation of macromolecule biosynthetic process; and...
Does Knockout of Usp34 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Usp34
protein/peptide distribution
Microglial Cell Line
Gene: Usp34 (ubiquitin specific peptidase 34) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, positive regulation of canonical Wnt signaling pathway, post-translational protein modification, protein K48-linked deubiquitination, protein deubiquitinat...
Does Knockout of Nmbr in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Nmbr
protein/peptide distribution
Microglial Cell Line
Gene: Nmbr (neuromedin B receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, antiviral innate immune response, bombesin receptor signaling pathway, negative regulation of interleukin-6 production, neuropeptide signaling ...
Does Knockout of Plagl2 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Plagl2
cell cycle progression
breast epithelium
Gene: Plagl2 (pleiomorphic adenoma gene-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chylomicron assembly, lipid metabolic process, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of transcription by RNA polymerase II, post-emb...
Does Knockout of Ivl in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Ivl
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ivl (involucrin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: keratinization, keratinocyte differentiation, regulation of antibacterial peptide production, response to UV-B; CC: centrosome, cornified envelope, cytoplasm, cytosol, nuclear body Pathways: ...
Does Knockout of Adra2c in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Adra2c
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Adra2c (adrenergic receptor, alpha 2c) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, adrenergic receptor signaling pathway, epidermal growth fa...
Does Knockout of Col9a3 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Col9a3
response to virus
Embryonic Fibroblast Cell Line
Gene: Col9a3 (collagen, type IX, alpha 3) Type: protein-coding Summary: Predicted to enable protein homodimerization activity. Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Predicted to be part o...
Does Knockout of Vps35 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Vps35
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Vps35 (VPS35 retromer complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endocytic recycling, intracellular protein transport, lysosome organization, mitochondrial fragmentation involved in apoptotic process, mitochondrion to lysosome vesicle-mediate...
Does Knockout of Piezo2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Piezo2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Piezo2 (piezo-type mechanosensitive ion channel component 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to mechanical stimulus, detection of mechanical stimulus, detection of mechanical stimulus involved in sensory perception, monoatomic catio...
Does Knockout of Akr1a1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Akr1a1
cell proliferation
Mouse kidney carcinoma cell
Gene: Akr1a1 (aldo-keto reductase family 1, member A1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-glucuronate catabolic process, D-glucuronate catabolic process to D-xylulose 5-phosphate, L-ascorbic acid biosynthetic process, aldehyde catabolic process, cellular de...
Does Knockout of Ttll4 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Ttll4
autophagy
Embryonic Fibroblast Cell Line
Gene: Ttll4 (tubulin tyrosine ligase-like family, member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule cytoskeleton organization, peptidyl-glutamic acid modification, protein polyglutamylation, regulation of blastocyst development; MF: ATP binding, ligase...
Does Knockout of Mrps12 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Mrps12
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mrps12 (mitochondrial ribosomal protein S12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondrion, ribon...
Does Knockout of Ubxn1 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Ubxn1
protein/peptide distribution
myoblast cell line
Gene: Ubxn1 (UBX domain protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of ERAD pathway, negative regulation of proteasomal ubiquitin-dependent protein catabolic process, negative regulation of protein K48-linked deubiquitination, negative r...
Does Knockout of Letm1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Letm1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Letm1 (leucine zipper-EF-hand containing transmembrane protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium export from the mitochondrion, calcium ion transport, cristae formation, inner mitochondrial membrane organization, mitochondrial calcium ion ho...
Does Knockout of Fam20a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Fam20a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Fam20a (FAM20A, golgi associated secretory pathway pseudokinase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biomineral tissue development, calcium ion homeostasis, enamel mineralization, positive regulation of protein phosphorylation, response to bacterium, too...
Does Knockout of Gpbp1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Gpbp1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gpbp1 (GC-rich promoter binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, positive regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II, regulation of DNA-templated transcr...
Does Knockout of Sfswap in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Sfswap
cell proliferation
Colonic Cancer Cell Line
Gene: Sfswap (splicing factor SWAP) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA processing, RNA splicing, alternative mRNA splicing, via spliceosome, mRNA 5'-splice site recognition, mRNA processing, negative regulation of mRNA splicing, via spliceosome; MF: RNA b...
Does Knockout of Ap2s1 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,271
Knockout
Ap2s1
cell proliferation
Mouse kidney carcinoma cell
Gene: Ap2s1 (adaptor-related protein complex 2, sigma 1 subunit) Type: protein-coding Summary: Predicted to enable clathrin adaptor activity. Predicted to be involved in postsynaptic neurotransmitter receptor internalization and synaptic vesicle endocytosis. Part of AP-2 adaptor complex. Is active in sy...
Does Knockout of Ccdc185 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Ccdc185
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Ccdc185 (coiled-coil domain containing 185) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q3V118 Entrez ID: 433386
Does Knockout of Park7 in Lymphoma Cell Line causally result in response to chemicals?
0
1,543
Knockout
Park7
response to chemicals
Lymphoma Cell Line
Gene: Park7 (Parkinson disease (autosomal recessive, early onset) 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, adult locomotory behavior, androgen receptor signaling pathway, autophagy, cellular detoxification of aldehyde, cellular d...
Does Knockout of Ak1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Ak1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Ak1 (adenylate kinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ADP biosynthetic process, AMP metabolic process, ATP metabolic process, inosine biosynthetic process, nucleobase-containing compound metabolic process, nucleoside monophosphate phosphorylation,...
Does Knockout of Tmem269 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Tmem269
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Tmem269 (transmembrane protein 269) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9D4Y8 Entrez ID: 75180
Does Knockout of Ubl5 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Ubl5
cell viability
Immortal mouse chromaffin cells
Gene: Ubl5 (ubiquitin-like 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA splicing, via spliceosome, protein modification process; CC: cytoplasm, nucleus Pathways: Metabolism of RNA, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing, mRNA Sp...
Does Knockout of Dexi in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Dexi
cell proliferation
Colonic Cancer Cell Line
Gene: Dexi (dexamethasone-induced transcript) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9WUQ7 Entrez ID: 58239
Does Knockout of Actr10 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Actr10
cell proliferation
Melanoma Cell Line
Gene: Actr10 (ARP10 actin-related protein 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule-based movement, retrograde axonal transport of mitochondrion; CC: axon cytoplasm, cytoplasm, cytoskeleton, dynactin complex Pathways: Adaptive Immune System,...
Does Knockout of Pgm1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Pgm1
cell proliferation
Mouse kidney carcinoma cell
Gene: Pgm1 (phosphoglucomutase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate metabolic process, galactose catabolic process via UDP-galactose, Leloir pathway, glucose metabolic process, glycogen biosynthetic process, glycogen catabolic process; MF: intra...
Does Knockout of Mapk15 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Mapk15
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Mapk15 (mitogen-activated protein kinase 15) Type: protein-coding Summary: Predicted to enable MAP kinase activity and chromatin binding activity. Involved in positive regulation of metaphase/anaphase transition of meiosis I; positive regulation of spindle assembly; and regulation of cilium assemb...
Does Knockout of Cdk13 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Cdk13
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cdk13 (cyclin dependent kinase 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, alternative mRNA splicing, via spliceosome, hemopoiesis, mRNA processing, negative regulation of stem cell differentiation, positive regulation of transcription by RNA p...
Does Knockout of Mecr in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,289
Knockout
Mecr
cell proliferation
Mouse kidney carcinoma cell
Gene: Mecr (mitochondrial trans-2-enoyl-CoA reductase) Type: protein-coding Summary: Predicted to enable enoyl-[acyl-carrier-protein] reductase (NADPH) activity; nuclear receptor binding activity; and signaling receptor binding activity. Predicted to be involved in fatty acid metabolic process. Located ...
Does Knockout of Tlr8 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Tlr8
cell proliferation
Mouse kidney carcinoma cell
Gene: Tlr8 (toll-like receptor 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: canonical NF-kappaB signal transduction, cellular response to mechanical stimulus, defense response to virus, immune system process, inflammatory response, innate immune response, negative r...
Does Knockout of Sdhc in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Sdhc
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sdhc (succinate dehydrogenase complex, subunit C, integral membrane protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial electron transport, succinate to ubiquinone, proton motive force-driven mitochondrial ATP synthesis, tricarboxylic acid cycle; ...
Does Knockout of Defb50 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Defb50
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Defb50 (defensin beta 50) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, defense response, defense response to bacterium; CC: cellular_component, extracellular region Pathways: UniProt: Q6TU36 Entrez ID: 387334
Does Knockout of Iffo2 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Iffo2
cell proliferation
Melanoma Cell Line
Gene: Iffo2 (intermediate filament family orphan 2) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, intermediate filament Pathways: UniProt: Q8R2V2 Entrez ID: 212632
Does Knockout of Cldn20 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Cldn20
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cldn20 (claudin 20) Type: protein-coding Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the para...
Does Knockout of Agmo in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Agmo
protein/peptide distribution
myoblast cell line
Gene: Agmo (alkylglycerol monooxygenase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ether lipid metabolic process, lipid biosynthetic process, lipid metabolic process, membrane lipid metabolic process, triglyceride biosynthetic process; MF: glyceryl-ether monooxygena...
Does Knockout of Psma7 in Embryonic Stem Cell Line causally result in cell proliferation?
1
578
Knockout
Psma7
cell proliferation
Embryonic Stem Cell Line
Gene: Psma7 (proteasome subunit alpha 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis involved in protein catabolic process, ubiquitin-dependent protein catabolic process; MF: identical prot...
Does Knockout of Scrn1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Scrn1
cell proliferation
Mouse kidney carcinoma cell
Gene: Scrn1 (secernin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: exocytosis, proteolysis, regulation of synaptic vesicle cycle; MF: cysteine-type exopeptidase activity, dipeptidase activity, molecular_function; CC: cytoplasm, nuclear membrane, nucleus, presynapse ...
Does Knockout of Trappc6b in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,287
Knockout
Trappc6b
cell proliferation
Mouse kidney carcinoma cell
Gene: Trappc6b (trafficking protein particle complex 6B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi vesicle transport, endoplasmic reticulum to Golgi vesicle-mediated transport, nervous system development, vesicle coating, vesicle tethering; CC: Golgi apparatus...
Does Knockout of Fam210b in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Fam210b
cell proliferation
Mouse kidney carcinoma cell
Gene: Fam210b (family with sequence similarity 210, member B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cellular response to estradiol stimulus, erythrocyte differentiation, erythrocyte maturation, inflammatory response, positive regulation of ...
Does Knockout of Elp5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Elp5
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Elp5 (elongator acetyltransferase complex subunit 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of cell migration, tRNA modification, tRNA processing, tRNA wobble uridine modification; CC: cytoplasm, cytosol, elongator holoenzyme complex, nu...
Does Knockout of Cdc16 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Cdc16
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Cdc16 (CDC16 cell division cycle 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anaphase-promoting complex-dependent catabolic process, cell division, positive regulation of mitotic metaphase/anaphase transition, protein K11-linked ubiquitination, protein K48-l...
Does Knockout of Znfx1 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Znfx1
protein/peptide distribution
myoblast cell line
Gene: Znfx1 (zinc finger, NFX1-type containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: activation of innate immune response, defense response to bacterium, defense response to virus, immune system process, innate immune response, negative regulation of viral ge...
Does Knockout of Hoxb2 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Hoxb2
cell proliferation
Melanoma Cell Line
Gene: Hoxb2 (homeobox B2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterior/posterior pattern specification, dorsal/ventral pattern formation, embryonic skeletal system morphogenesis, facial nerve structural organization, morphogenesis of an epithelial sheet, neura...
Does Knockout of Ctcf in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
1,130
Knockout
Ctcf
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ctcf (CCCTC-binding factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA methylation-dependent constitutive heterochromatin formation, cardiac muscle cell development, cardiac muscle cell differentiation, chromatin looping, chromatin organization, chromosome ...
Does Knockout of Ythdf1 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Ythdf1
protein/peptide distribution
myoblast cell line
Gene: Ythdf1 (YTH N6-methyladenosine RNA binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: immune system process, learning, mRNA destabilization, memory, organelle assembly, positive regulation of translation, positive regulation of translational initiati...
Does Knockout of Hoxc12 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Hoxc12
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Hoxc12 (homeobox C12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-speci...
Does Knockout of Tmem41b in Melanoma Cell Line causally result in cell proliferation?
1
2,492
Knockout
Tmem41b
cell proliferation
Melanoma Cell Line
Gene: Tmem41b (transmembrane protein 41B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, autophagy, host-mediated perturbation of viral RNA genome replication, intracellular lipid transport, lipid transport, nervous system development, plasma memb...
Does Knockout of Nbn in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,152
Knockout
Nbn
protein/peptide accumulation
Embryonic Cell Line
Gene: Nbn (nibrin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage checkpoint signaling, DNA damage response, DNA double-strand break processing, DNA repair, DNA strand resection involved in replication fork processing, R-loop processing, blastocyst growth, dou...
Does Knockout of Sh3bp5 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Sh3bp5
protein/peptide accumulation
Regulatory T cell
Gene: Sh3bp5 (SH3-domain binding protein 5 (BTK-associated)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular signal transduction, negative regulation of protein kinase activity; MF: SH3 domain binding, guanyl-nucleotide exchange factor activity, protein kina...
Does Knockout of Slc25a34 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Slc25a34
cell proliferation
Melanoma Cell Line
Gene: Slc25a34 (solute carrier family 25, member 34) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane, mitochondrial inner membrane, mitochondrion Pathways: UniProt: A2ADF7 Entrez ID: 384071
Does Knockout of Satl1 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Satl1
cell proliferation
Embryonic Stem Cell Line
Gene: Satl1 (spermidine/spermine N1-acetyl transferase-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: polyamine metabolic process, spermidine acetylation; MF: acyltransferase activity, acyltransferase activity, transferring groups other than amino-acyl groups, di...
Does Knockout of Cpsf3 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Cpsf3
cell proliferation
Embryonic Stem Cell Line
Gene: Cpsf3 (cleavage and polyadenylation specificity factor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, mRNA 3'-end processing, mRNA 3'-end processing by stem-loop binding and cleavag...
Does Knockout of Nsun6 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Nsun6
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Nsun6 (NOL1/NOP2/Sun domain family member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA methylation, methylation, tRNA C5-cytosine methylation, tRNA methylation, tRNA modification; MF: RNA binding, RNA methyltransferase activity, methyltransferase activity,...
Does Knockout of Phlda3 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Phlda3
cell proliferation
Colonic Cancer Cell Line
Gene: Phlda3 (pleckstrin homology like domain, family A, member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator, negative regulation of phosphatidylinositol 3-kinas...
Does Knockout of Hs6st2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Hs6st2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Hs6st2 (heparan sulfate 6-O-sulfotransferase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: heparan sulfate proteoglycan biosynthetic process; MF: heparan sulfate 6-sulfotransferase activity, sulfotransferase activity, transferase activity; CC: Golgi apparatus, ...
Does Knockout of Ccnk in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,271
Knockout
Ccnk
cell proliferation
Mouse kidney carcinoma cell
Gene: Ccnk (cyclin K) Type: protein-coding Summary: Predicted to enable cyclin-dependent protein serine/threonine kinase activator activity; protein kinase binding activity; and protein serine/threonine kinase activity. Acts upstream of or within in utero embryonic development and negative regulation of...
Does Knockout of Tm9sf1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Tm9sf1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Tm9sf1 (transmembrane 9 superfamily member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagy, protein localization to membrane; CC: autophagosome membrane, cytoplasmic vesicle, lysosomal membrane, lysosome, membrane Pathways: UniProt: Q...
Does Knockout of Muc13 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Muc13
protein/peptide accumulation
Mouse cell
Gene: Muc13 (mucin 13, epithelial transmembrane) Type: protein-coding Summary: No summary available. Gene Ontology: CC: apical plasma membrane, cell periphery, cytosol, extracellular region, extracellular space, membrane, plasma membrane Pathways: Metabolism of proteins, O-linked glyco...
Does Knockout of Aadat in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Aadat
protein/peptide distribution
myoblast cell line
Gene: Aadat (aminoadipate aminotransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 2-oxoglutarate metabolic process, L-lysine catabolic process to acetyl-CoA via saccharopine, alpha-amino acid metabolic process, glutamate metabolic process, kynurenine metabolic p...
Does Knockout of Bcl2l12 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Bcl2l12
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Bcl2l12 (BCL2 like 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, negative regulation of apoptotic process, negative regulation of cellular senescence, negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by ...
Does Knockout of Chrd in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Chrd
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Chrd (chordin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: BMP signaling pathway, artery morphogenesis, cell population proliferation, central nervous system development, chordate pharynx development, cranial skeletal system development, descending aorta develop...
Does Knockout of Taf3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Taf3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Taf3 (TATA-box binding protein associated factor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, chromatin organization, mRNA transcription by RNA polymerase II, maintenance of protein location in nucleus, negativ...
Does Knockout of Nmral1 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Nmral1
protein/peptide distribution
myoblast cell line
Gene: Nmral1 (NmrA-like family domain containing 1) Type: protein-coding Summary: Predicted to enable identical protein binding activity. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brain; eye; genitourinary system; gut; and lu...
Does Knockout of Rnf207 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Rnf207
cell proliferation
Mouse kidney carcinoma cell
Gene: Rnf207 (ring finger protein 207) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of gene expression, positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential, regulation of cardiac muscle contraction,...
Does Knockout of Tlr7 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Tlr7
protein/peptide accumulation
Embryonic Cell Line
Gene: Tlr7 (toll-like receptor 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: JNK cascade, MAPK cascade, canonical NF-kappaB signal transduction, cellular response to mechanical stimulus, cellular response to virus, defense response to virus, immune system process, in...
Does Knockout of Aldh1a2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Aldh1a2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Aldh1a2 (aldehyde dehydrogenase family 1, subfamily A2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 9-cis-retinoic acid biosynthetic process, aldehyde metabolic process, anterior/posterior pattern specification, blood vessel development, camera-type eye developm...
Does Knockout of Spock2 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Spock2
cell proliferation
Melanoma Cell Line
Gene: Spock2 (sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to leukemia inhibitory factor, extracellular matrix organization, positive regulation of cell-substrate adhesion; MF: calcium ion...
Does Knockout of Flot2 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Flot2
protein/peptide distribution
myoblast cell line
Gene: Flot2 (flotillin 2) Type: protein-coding Summary: Predicted to enable ionotropic glutamate receptor binding activity and protease binding activity. Involved in anterograde dendritic transport; regulation of myoblast differentiation; and regulation of postsynaptic membrane neurotransmitter receptor...
Does Knockout of Mrpl30 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Mrpl30
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Mrpl30 (mitochondrial ribosomal protein L30) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: molecular_function, structural constituent of ribosome; CC: large ribosomal subunit, mitochondrial inner membrane, mitochondrial ...
Does Knockout of Irx2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Irx2
cell proliferation
Mouse kidney carcinoma cell
Gene: Irx2 (Iroquois homeobox 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, cell development, metanephros development, negative regulation of transcription by RNA polymerase II, neuron differentiation, proximal/distal pattern formation invol...
Does Knockout of Sp110 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Sp110
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Sp110 (Sp110 nuclear body protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, immune system process, innate immune response, positive regulation of apoptotic process, regulation of transcription by RNA polymerase II, response to bacterium; MF...
Does Knockout of Gm3604 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Gm3604
response to virus
Embryonic Fibroblast Cell Line
Gene: Gm3604 (predicted gene 3604) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA poly...
Does Knockout of Nkx6-1 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Nkx6-1
protein/peptide distribution
myoblast cell line
Gene: Nkx6-1 (NK6 homeobox 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cellular response to cytokine stimulus, cellular response to peptide hormone stimulus, central nervous system neuron differentiation, endocrine pancreas development, entero...