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Does Knockout of Stfa1 in Microglial Cell Line causally result in response to virus?
0
1,438
Knockout
Stfa1
response to virus
Microglial Cell Line
Gene: Stfa1 (stefin A1) Type: protein-coding Summary: Enables endopeptidase inhibitor activity. Acts upstream of or within negative regulation of endopeptidase activity. Located in cytoplasm. Human ortholog(s) of this gene implicated in peeling skin syndrome 4. Orthologous to human CSTA (cystatin A). [p...
Does Knockout of Bank1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Bank1
cell proliferation
Embryonic Stem Cell Line
Gene: Bank1 (B cell scaffold protein with ankyrin repeats 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation, negative regulation of B cell activation, negative regulation of interleukin-6 production, negative regulation of phosphatidylinositol 3-kinase/...
Does Knockout of Aamp in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Aamp
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Aamp (angio-associated migratory protein) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cell surface, cytoplasm, intercellular bridge, microtubule cytoskeleton, plasma membrane Pathways: Hemostasis, Immune System, Innate Immune System, NOD1/2 Signaling Pa...
Does Knockout of Il13ra1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Il13ra1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Il13ra1 (interleukin 13 receptor, alpha 1) Type: protein-coding Summary: This gene encodes a transmembrane protein that complexes with interleukin 4 receptor alpha (IL4RA) to form a functional receptor for interleukin-13. Signalling through this pathway mediates allergy response and occurs during ...
Does Knockout of Fem1b in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Fem1b
cell cycle progression
breast epithelium
Gene: Fem1b (fem 1 homolog b) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, branching involved in prostate gland morphogenesis, developmental process involved in reproduction, epithelial cell maturation, epithelial cell maturation involved in prostate...
Does Knockout of Fibp in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Fibp
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Fibp (fibroblast growth factor (acidic) intracellular binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: MF: fibroblast growth factor binding; CC: endomembrane system, membrane, nuclear speck, nucleus Pathways: UniProt: Q9JI19 En...
Does Knockout of Tmem62 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Tmem62
cell proliferation
Mouse kidney carcinoma cell
Gene: Tmem62 (transmembrane protein 62) Type: protein-coding Summary: No summary available. Gene Ontology: MF: hydrolase activity, molecular_function; CC: cellular_component, membrane Pathways: UniProt: Q8BXJ9 Entrez ID: 96957
Does Knockout of B3gnt9 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
B3gnt9
cell cycle progression
breast epithelium
Gene: B3gnt9 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: poly-N-acetyllactosamine biosynthetic process, protein O-linked glycosylation, protein glycosylation; MF: UDP-glycosyltransferase activity, glycosy...
Does Knockout of Vmn1r57 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Vmn1r57
protein/peptide distribution
myoblast cell line
Gene: Vmn1r57 (vomeronasal 1 receptor 57) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor ...
Does Knockout of H2-Eb2 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
H2-Eb2
protein/peptide accumulation
Microglial Cell Line
Gene: H2-Eb2 (histocompatibility 2, class II antigen E beta2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processi...
Does Knockout of Kti12 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Kti12
cell proliferation
Mouse kidney carcinoma cell
Gene: Kti12 (KTI12 homolog, chromatin associated) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, molecular_function, nucleotide binding Pathways: UniProt: Q9D1R2 Entrez ID: 100087
Does Knockout of Mrpl42 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,268
Knockout
Mrpl42
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Mrpl42 (mitochondrial ribosomal protein L42) Type: protein-coding Summary: No summary available. Gene Ontology: CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrial small ribosomal subunit, mitochondrion, plasma membrane, ribonucleoprotein complex, riboso...
Does Knockout of Slc22a22 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Slc22a22
cell proliferation
Regulatory T cell
Gene: Slc22a22 (solute carrier family 22 (organic cation transporter), member 22) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, monoatomic ion transport, organic anion transport, sodium-independent prostaglandin transport, t...
Does Knockout of A930011G23Rik in macrophage causally result in phagocytosis?
0
1,890
Knockout
A930011G23Rik
phagocytosis
macrophage
Gene: A930011G23Rik (RIKEN cDNA A930011G23 gene) Type: ncRNA Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 319818
Does Knockout of Fem1a in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Fem1a
cell proliferation
Melanoma Cell Line
Gene: Fem1a (fem 1 homolog a) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, negative regulation of inflammatory response, positive regulation of inflammatory response, proteasome-mediated ubiquitin-dependent protein catabolic process, protein ubiquitinatio...
Does Knockout of Vmn1r216 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Vmn1r216
cell proliferation
Embryonic Stem Cell Line
Gene: Vmn1r216 (vomeronasal 1 receptor 216) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8R257 Entrez ID: 171279
Does Knockout of Rps6ka4 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Rps6ka4
cell proliferation
Mouse kidney carcinoma cell
Gene: Rps6ka4 (ribosomal protein S6 kinase, polypeptide 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: TORC1 signaling, chromatin remodeling, inflammatory response, interleukin-1-mediated signaling pathway, intracellular signal transduction, positive regulation of tra...
Does Knockout of G2e3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
G2e3
cell proliferation
Mouse kidney carcinoma cell
Gene: G2e3 (G2/M-phase specific E3 ubiquitin ligase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, blastocyst development, negative regulation of intrinsic apoptotic signaling pathway, protein polyubiquitination, protein ubiquitination; MF: metal ion ...
Does Knockout of Ndufb5 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Ndufb5
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ndufb5 (NADH:ubiquinone oxidoreductase subunit B5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, proton motive force-driven mitochondrial ATP synthesis; CC: membrane, mitochondrial inner membrane, mitochondrion, nucleoplasm, respiratory chain ...
Does Knockout of Cysrt1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Cysrt1
cell proliferation
Colonic Cancer Cell Line
Gene: Cysrt1 (cysteine rich tail 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological process involved in interaction with symbiont, biological_process, establishment of skin barrier; MF: identical protein binding, molecular_function; CC: cornified envelope ...
Does Knockout of Pld6 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Pld6
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Pld6 (phospholipase D family member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: P granule organization, cell differentiation, lipid catabolic process, lipid metabolic process, meiotic cell cycle, mitochondrial fusion, phospholipid biosynthetic process, piRNA ...
Does Knockout of Sucla2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Sucla2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Sucla2 (succinate-Coenzyme A ligase, ADP-forming, beta subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: succinate metabolic process, succinyl-CoA metabolic process, tricarboxylic acid cycle; MF: ATP binding, catalytic activity, ligase activity, magnesium ion...
Does Knockout of Gtf2a1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Gtf2a1
cell proliferation
Mouse kidney carcinoma cell
Gene: Gtf2a1 (general transcription factor II A, 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, positive regulation of transcription by RNA polymerase II, positive regulation of transcription initiation by RNA polymera...
Does Knockout of Vmn1r81 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Vmn1r81
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Vmn1r81 (vomeronasal 1 receptor 81) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromone ...
Does Knockout of Stx19 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Stx19
protein/peptide distribution
myoblast cell line
Gene: Stx19 (syntaxin 19) Type: protein-coding Summary: No summary available. Gene Ontology: BP: exocytosis, intracellular protein transport, synaptic vesicle fusion to presynaptic active zone membrane, vesicle docking, vesicle-mediated transport; MF: SNAP receptor activity, SNARE binding; CC: ...
Does Knockout of Zfp30 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Zfp30
response to virus
Embryonic Fibroblast Cell Line
Gene: Zfp30 (zinc finger protein 30) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA po...
Does Knockout of Itgam in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Itgam
response to chemicals
Pancreatic Cancer Cell Line
Gene: Itgam (integrin alpha M) Type: protein-coding Summary: Enables complement component C3b binding activity; heparan sulfate proteoglycan binding activity; and heparin binding activity. Contributes to cargo receptor activity. Involved in several processes, including central nervous system development...
Does Knockout of Dnm2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Dnm2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Dnm2 (dynamin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor internalization, Golgi to plasma membrane transport, actin filament bundle organization, aorta development, autophagy, cellular response to dopamine, centrosome cycle, corona...
Does Knockout of Ktn1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Ktn1
protein/peptide accumulation
Embryonic Cell Line
Gene: Ktn1 (kinectin 1) Type: protein-coding Summary: Predicted to enable kinesin binding activity. Predicted to be involved in protein transport. Predicted to act upstream of or within microtubule-based movement. Located in endoplasmic reticulum. Is expressed in several structures, including genitourin...
Does Knockout of Vdr in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,268
Knockout
Vdr
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Vdr (vitamin D (1,25-dihydroxyvitamin D3) receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ morphogenesis, apoptotic signaling pathway, calcium ion transport, cell differentiation, cell morphogenesis, cell-cell junction maintenance, decidualizat...
Does Knockout of Crisp3 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,277
Knockout
Crisp3
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Crisp3 (cysteine-rich secretory protein 3) Type: protein-coding Summary: Predicted to be involved in sexual reproduction. Predicted to be located in extracellular region and transport vesicle. Predicted to be active in extracellular space. Is expressed in sublingual gland and submandibular gland. ...
Does Knockout of L1cam in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
L1cam
protein/peptide accumulation
Embryonic Cell Line
Gene: L1cam (L1 cell adhesion molecule) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon development, axon guidance, axonal fasciculation, cell adhesion, cell differentiation, cell migration, cell surface receptor signaling pathway, cell-cell adhesion mediated by inte...
Does Knockout of Snx12 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Snx12
protein/peptide accumulation
Embryonic Cell Line
Gene: Snx12 (sorting nexin 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endocytic recycling, late endosome to Golgi transport, negative regulation of early endosome to late endosome transport, negative regulation of gene expression, negative regulation of protein c...
Does Knockout of Nudt4 in Melanoma Cell Line causally result in cell proliferation?
0
1,281
Knockout
Nudt4
cell proliferation
Melanoma Cell Line
Gene: Nudt4 (nudix hydrolase 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adenosine 5'-(hexahydrogen pentaphosphate) catabolic process, diadenosine hexaphosphate catabolic process, diadenosine pentaphosphate catabolic process, diphosphoinositol polyphosphate metabol...
Does Knockout of Vmn1r203 in Cytotoxic T-lymphocyte (CD8+ T cells) causally result in cell proliferation?
1
2,411
Knockout
Vmn1r203
cell proliferation
Cytotoxic T-lymphocyte (CD8+ T cells)
Gene: Vmn1r203 (vomeronasal 1 receptor 203) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromon...
Does Knockout of Ephx1 in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Ephx1
cell proliferation
Melanoma Cell Line
Gene: Ephx1 (epoxide hydrolase 1, microsomal) Type: protein-coding Summary: No summary available. Gene Ontology: BP: arachidonate metabolic process, cellular response to glucocorticoid stimulus, diol biosynthetic process, epoxide metabolic process, hydrocarbon catabolic process, lipid metabolic...
Does Knockout of Klk10 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,179
Knockout
Klk10
cell proliferation
Colonic Cancer Cell Line
Gene: Klk10 (kallikrein related-peptidase 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein maturation, proteolysis; MF: protein binding, serine-type endopeptidase activity; CC: extracellular space, secretory granule Pathways: UniProt: Q99M20 ...
Does Knockout of Mslnl in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Mslnl
protein/peptide distribution
myoblast cell line
Gene: Mslnl (mesothelin-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell-matrix adhesion; CC: cell surface, membrane Pathways: UniProt: Q8C160 Entrez ID: 328783
Does Knockout of Snx7 in Regulatory T cell causally result in cell proliferation?
0
1,483
Knockout
Snx7
cell proliferation
Regulatory T cell
Gene: Snx7 (sorting nexin 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endocytic recycling, mitophagy, piecemeal microautophagy of the nucleus, positive regulation of autophagosome assembly, protein transport, reticulophagy; MF: lipid binding, phosphatidylinositol b...
Does Knockout of Btbd18 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Btbd18
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Btbd18 (BTB domain containing 18) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, male meiosis I, piRNA transcription, positive regulation of transcription elongation by RNA polymerase II, spermatogenesis, transposable element silencing; CC: nu...
Does Knockout of Pum2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,259
Knockout
Pum2
cell proliferation
Mouse kidney carcinoma cell
Gene: Pum2 (pumilio RNA-binding family member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adipose tissue development, chromosome organization, hair follicle development, miRNA processing, mitochondrion organization, negative regulation of gene expression, positive ...
Does Knockout of Ccdc90b in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Ccdc90b
protein/peptide accumulation
Embryonic Cell Line
Gene: Ccdc90b (coiled-coil domain containing 90B) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane, mitochondrial membrane, mitochondrion Pathways: UniProt: Q8C3X2 Entrez ID: 66365
Does Knockout of Slc27a4 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Slc27a4
protein/peptide accumulation
Embryonic Cell Line
Gene: Slc27a4 (solute carrier family 27 (fatty acid transporter), member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: establishment of localization in cell, fatty acid metabolic process, fatty acid transport, glucose import in response to insulin stimulus, lipid met...
Does Knockout of Gm10322 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Gm10322
phagocytosis
macrophage
Gene: Gm10322 (predicted gene 10322) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Cracr2b in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,663
Knockout
Cracr2b
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cracr2b (calcium release activated channel regulator 2B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, store-operated calcium entry; MF: calcium ion binding, molecular_function, ubiquitin-protein transferase activity Pathways: ...
Does Knockout of Itln1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Itln1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Itln1 (intelectin 1 (galactofuranose binding)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of D-glucose import, positive regulation of protein phosphorylation, response to nematode; MF: calcium ion binding, carbohydrate binding, identical pro...
Does Knockout of Cyp2c55 in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Cyp2c55
cell proliferation
Melanoma Cell Line
Gene: Cyp2c55 (cytochrome P450, family 2, subfamily c, polypeptide 55) Type: protein-coding Summary: No summary available. Gene Ontology: BP: arachidonate metabolic process, epoxygenase P450 pathway, linoleic acid metabolic process, retinoic acid metabolic process, xenobiotic catabolic process;...
Does Knockout of Slc30a5 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Slc30a5
cell cycle progression
breast epithelium
Gene: Slc30a5 (solute carrier family 30 (zinc transporter), member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GPI anchor biosynthetic process, cobalt ion transport, insulin processing, intracellular zinc ion homeostasis, monoatomic cation transport, monoatomic ion...
Does Knockout of Cdk19 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Cdk19
cell proliferation
Embryonic Stem Cell Line
Gene: Cdk19 (cyclin dependent kinase 19) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to lipopolysaccharide, positive regulation of apoptotic process, regulation of cell cycle; MF: ATP binding, cyclin-dependent protein serine/threonine kinase activity...
Does Knockout of Mark4 in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Mark4
cell proliferation
Melanoma Cell Line
Gene: Mark4 (MAP/microtubule affinity regulating kinase 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, cell projection organization, cilium disassembly, cilium organization, intracellular signal transduction, microtubule bundle formation, microtubule cy...
Does Knockout of Dlx4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Dlx4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dlx4 (distal-less homeobox 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, embryonic skeletal system development, negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcripti...
Does Knockout of Ccnc in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Ccnc
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ccnc (cyclin C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G0 to G1 transition, negative regulation of Notch signaling pathway, negative regulation of triglyceride metabolic process, positive regulation of transcription by RNA polymerase II, protein ubiquitinat...
Does Knockout of Pygb in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Pygb
cell proliferation
Mouse kidney carcinoma cell
Gene: Pygb (brain glycogen phosphorylase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate metabolic process, glycogen catabolic process, glycogen metabolic process; MF: 1,4-alpha-oligoglucan phosphorylase activity, carbohydrate binding, catalytic activity, gl...
Does Knockout of Col11a1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Col11a1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Col11a1 (collagen, type XI, alpha 1) Type: protein-coding Summary: This gene encodes the alpha-1 subunit of type XI collagen, one of the low abundance fibrillar collagens that is essential for normal embryonic skeletal development and the cohesive properties of cartilage. The encoded protein, in a...
Does Knockout of Mcrs1 in Pancreatic Cell Line causally result in protein/peptide accumulation?
0
2,195
Knockout
Mcrs1
protein/peptide accumulation
Pancreatic Cell Line
Gene: Mcrs1 (microspherule protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, chromatin organization, chromatin remodeling, negative regulation of telomere maintenance via telomere lengthening, positive regulatio...
Does Knockout of Foxp2 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Foxp2
protein/peptide accumulation
Mouse cell
Gene: Foxp2 (forkhead box P2) Type: protein-coding Summary: Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; identical protein binding activity; and transcription coregulator binding activity. Involved in cerebellar Purkinje cell differentiat...
Does Knockout of Rbm12 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Rbm12
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Rbm12 (RNA binding motif protein 12) Type: protein-coding Summary: This gene encodes a protein that contains several RNA-binding motifs, potential transmembrane domains, and proline-rich regions. This gene and the gene for copine I overlap at map location 2 H2. Two alternatively spliced transcript...
Does Knockout of Polr2j in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Polr2j
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Polr2j (polymerase (RNA) II (DNA directed) polypeptide J) Type: protein-coding Summary: Predicted to enable LRR domain binding activity. Predicted to contribute to DNA-directed RNA polymerase activity. Predicted to be involved in transcription by RNA polymerase II. Located in nucleus. Part of RNA ...
Does Knockout of Mfsd6l in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Mfsd6l
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Mfsd6l (major facilitator superfamily domain containing 6-like) Type: protein-coding Summary: Predicted to be active in membrane. Orthologous to human MFSD6L (major facilitator superfamily domain containing 6 like). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: CC: m...
Does Knockout of Ascl1 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Ascl1
response to virus
Embryonic Fibroblast Cell Line
Gene: Ascl1 (achaete-scute family bHLH transcription factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GABAergic neuron differentiation, Notch signaling pathway, adrenal chromaffin cell differentiation, carotid body glomus cell differentiation, cell differentiatio...
Does Knockout of Cracr2a in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Cracr2a
cell proliferation
Melanoma Cell Line
Gene: Cracr2a (calcium release activated channel regulator 2A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T-helper 1 cell differentiation, activation of store-operated calcium channel activity, adaptive immune response, calcium ion transport, endosomal transport, imm...
Does Knockout of Wwp1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Wwp1
cell proliferation
Mouse kidney carcinoma cell
Gene: Wwp1 (WW domain containing E3 ubiquitin protein ligase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell differentiation, lung development, negative regulation of DNA-templated transcription, proteasome-mediated ubiquitin-dependent protein catabolic process,...
Does Knockout of Impa2 in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Impa2
cell proliferation
Melanoma Cell Line
Gene: Impa2 (inositol monophosphatase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: inositol biosynthetic process, inositol metabolic process, phosphatidylinositol phosphate biosynthetic process, response to lithium ion, signal transduction; MF: glucose-1-phosphatase...
Does Knockout of Phc2 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Phc2
tumorigenicity
Colonic Cancer Cell Line
Gene: Phc2 (polyhomeotic 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, spermatogenesis; MF: DNA binding, chromatin binding, histone binding, identical protein binding, metal ion binding, protein binding, zinc ion bi...
Does Knockout of Gnl3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Gnl3
cell proliferation
Mouse kidney carcinoma cell
Gene: Gnl3 (guanine nucleotide binding protein nucleolar 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of miRNA transcription, positive regulation of protein localization to chromosome, telomeric region, positive regulation of protein sumoylation,...
Does Knockout of Nat2 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Nat2
cell viability
Immortal mouse chromaffin cells
Gene: Nat2 (N-acetyltransferase 2 (arylamine N-acetyltransferase)) Type: protein-coding Summary: No summary available. Gene Ontology: MF: N-acetyltransferase activity, N-hydroxyarylamine O-acetyltransferase activity, acetyltransferase activity, acyltransferase activity, arylamine N-acetyltransf...
Does Knockout of Prkaa1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Prkaa1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Prkaa1 (protein kinase, AMP-activated, alpha 1 catalytic subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CAMKK-AMPK signaling cascade, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, TORC1 signaling, Wnt signaling pathway, autophago...
Does Knockout of Snapc4 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Snapc4
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Snapc4 (small nuclear RNA activating complex, polypeptide 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: snRNA transcription by RNA polymerase II, snRNA transcription by RNA polymerase III; MF: DNA binding, RNA polymerase II cis-regulatory region sequence-specif...
Does Knockout of Osbpl8 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Osbpl8
cell proliferation
Mouse kidney carcinoma cell
Gene: Osbpl8 (oxysterol binding protein-like 8) Type: protein-coding Summary: This gene encodes a member of the oxysterol-binding protein (Osbp) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserv...
Does Knockout of Peak1 in myoblast cell line causally result in protein/peptide distribution?
1
1,683
Knockout
Peak1
protein/peptide distribution
myoblast cell line
Gene: Peak1 (pseudopodium-enriched atypical kinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell migration, focal adhesion assembly, regulation of cell motility, regulation of focal adhesion assembly, substrate adhesion-dependent cell spreading; MF: ATP binding,...
Does Knockout of Wdr5 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Wdr5
protein/peptide accumulation
Microglial Cell Line
Gene: Wdr5 (WD repeat domain 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, negative regulation of transcription by RNA polymerase II, neuron projection development, positive regulation of DNA-templated transcription, positive regulation of glu...
Does Knockout of Tssc4 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Tssc4
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Tssc4 (tumor-suppressing subchromosomal transferable fragment 4) Type: protein-coding Summary: Predicted to enable molecular sequestering activity. Predicted to be involved in spliceosomal tri-snRNP complex assembly. Predicted to be part of U5 snRNP. Predicted to be active in cytoplasm and nucleus...
Does Knockout of Rhof in Melanoma Cell Line causally result in cell proliferation?
0
2,488
Knockout
Rhof
cell proliferation
Melanoma Cell Line
Gene: Rhof (ras homolog family member F (in filopodia)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament organization, cell migration, regulation of actin cytoskeleton organization, signal transduction, small GTPase-mediated signal transduction; MF: GTP bind...
Does Knockout of Bet1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Bet1
cell proliferation
Mouse kidney carcinoma cell
Gene: Bet1 (Bet1 golgi vesicular membrane trafficking protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endoplasmic reticulum to Golgi vesicle-mediated transport, protein transport, vesicle fusion with Golgi apparatus, vesicle-mediated transport; MF: SNAP receptor ...
Does Knockout of Prkdc in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Prkdc
response to virus
Embryonic Fibroblast Cell Line
Gene: Prkdc (protein kinase, DNA activated, catalytic polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell lineage commitment, DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, T cell differentiation in thymus, T cell lineage commi...
Does Knockout of Snx9 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Snx9
phagocytosis
macrophage
Gene: Snx9 (sorting nexin 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, cleavage furrow formation, endocytosis, endosomal transport, intracellular protein transport, lipid tube assembly, mitotic cell cycle, mitotic cytokinesis, plasma membrane tubulati...
Does Knockout of Ahdc1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Ahdc1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ahdc1 (AT hook, DNA binding motif, containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, cell differentiation, mesoderm formation, regulation of DNA-templated transcription, skin morphogenesis; MF: DNA binding, DNA-binding transcription f...
Does Knockout of Tmem184b in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Tmem184b
cell proliferation
Mouse kidney carcinoma cell
Gene: Tmem184b (transmembrane protein 184b) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane Pathways: UniProt: Q8BG09 Entrez ID: 223693
Does Knockout of Taok3 in Lymphoma Cell Line causally result in response to chemicals?
0
1,542
Knockout
Taok3
response to chemicals
Lymphoma Cell Line
Gene: Taok3 (TAO kinase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, MAPK cascade, mitotic G2 DNA damage checkpoint signaling, negative regulation of JNK cascade, neuron projection morphogenesis, positive regulation of JNK cascade, p...
Does Knockout of Pik3c2b in Regulatory T cell causally result in cell proliferation?
0
1,483
Knockout
Pik3c2b
cell proliferation
Regulatory T cell
Gene: Pik3c2b (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome organization, cell migration, cellular response to starvation, lipid metabolic process, macroautophagy, phosphatidylinosit...
Does Knockout of Mvb12a in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Mvb12a
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Mvb12a (multivesicular body subunit 12A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endosome to lysosome transport via multivesicular body sorting pathway, protein transport, receptor catabolic process, regulation of epidermal growth factor receptor signaling p...
Does Knockout of Dram2 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Dram2
phagocytosis
macrophage
Gene: Dram2 (DNA-damage regulated autophagy modulator 2) Type: protein-coding Summary: Involved in photoreceptor cell maintenance. Acts upstream of or within cell population proliferation; phloem or xylem histogenesis; and retina development in camera-type eye. Located in apical plasma membrane and phot...
Does Knockout of Rax in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,261
Knockout
Rax
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Rax (retina and anterior neural fold homeobox) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, camera-type eye development, hypothalamus development, limb development, pattern specification process, positive regulation of transcription by RNA poly...
Does Knockout of Tle4 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Tle4
cell proliferation
Mouse kidney carcinoma cell
Gene: Tle4 (transducin-like enhancer of split 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, cellular response to leukemia inhibitory factor, negative regulation of DNA-templated transcription, negative regulation of canonical Wnt signaling path...
Does Knockout of Scn1b in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Scn1b
protein/peptide distribution
Microglial Cell Line
Gene: Scn1b (sodium channel, voltage-gated, type I, beta) Type: protein-coding Summary: Enables sodium channel inhibitor activity. Involved in several processes, including membrane depolarization during cardiac muscle cell action potential; regulation of sodium ion transport; and regulation of ventricul...
Does Knockout of Adar in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Adar
protein/peptide distribution
myoblast cell line
Gene: Adar (adenosine deaminase, RNA-specific) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RISC complex assembly, RNA processing, adenosine to inosine editing, base conversion or substitution editing, cellular response to virus, defense response to virus, definitive h...
Does Knockout of Rhpn1 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Rhpn1
cell cycle progression
breast epithelium
Gene: Rhpn1 (rhophilin, Rho GTPase binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: focal adhesion assembly, glomerular filtration, kidney development, negative regulation of stress fiber assembly, plasma membrane bounded cell projection morphogenesis, r...
Does Knockout of Zfp185 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Zfp185
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfp185 (zinc finger protein 185) Type: protein-coding Summary: No summary available. Gene Ontology: CC: anchoring junction, cytoplasm, cytoskeleton, focal adhesion Pathways: UniProt: Q62394 Entrez ID: 22673
Does Knockout of Ppp1r14b in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Ppp1r14b
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ppp1r14b (protein phosphatase 1, regulatory inhibitor subunit 14B) Type: protein-coding Summary: No summary available. Gene Ontology: MF: phosphatase inhibitor activity, protein phosphatase inhibitor activity, protein phosphatase regulator activity, protein serine/threonine phosphatase in...
Does Knockout of Terb2 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Terb2
response to virus
Neuroblastoma Cell Line
Gene: Terb2 (telomere repeat binding bouquet formation protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: double-strand break repair involved in meiotic recombination, homologous chromosome pairing at meiosis, meiotic attachment of telomere to nuclear envelope, me...
Does Knockout of Hnrnpf in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Hnrnpf
protein/peptide accumulation
Mouse cell
Gene: Hnrnpf (heterogeneous nuclear ribonucleoprotein F) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, regulation of RNA splicing; MF: RNA binding, TBP-class protein binding, nucleic acid binding, single-stranded RNA binding; CC: catalytic...
Does Knockout of 1700008O03Rik in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,260
Knockout
1700008O03Rik
cell proliferation
Mouse kidney carcinoma cell
Gene: 1700008O03Rik (RIKEN cDNA 1700008O03 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: D3Z070 Entrez ID: 69349
Does Knockout of Actrt3 in Melanoma Cell Line causally result in protein/peptide accumulation?
0
1,839
Knockout
Actrt3
protein/peptide accumulation
Melanoma Cell Line
Gene: Actrt3 (actin related protein T3) Type: protein-coding Summary: No summary available. Gene Ontology: CC: actin cytoskeleton, cytoplasm, cytoskeleton, male germ cell nucleus, nucleus Pathways: UniProt: Q8BXF8 Entrez ID: 76652
Does Knockout of Tdg in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Tdg
cell proliferation
Colonic Cancer Cell Line
Gene: Tdg (thymine DNA glycosylase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, base-excision repair, base-excision repair, AP site formation, chromatin organization, epigenetic regulation of gene expression, negative regulation of tra...
Does Knockout of Nlrp6 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,261
Knockout
Nlrp6
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Nlrp6 (NLR family, pyrin domain containing 6) Type: protein-coding Summary: The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the c...
Does Knockout of Slc39a7 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Slc39a7
protein/peptide accumulation
Microglial Cell Line
Gene: Slc39a7 (solute carrier family 39 (zinc transporter), member 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, intracellular zinc ion homeostasis, metal ion transport, monoatomic ion transport, regulation of ferroptosis, skin epidermis devel...
Does Knockout of Gm6710 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Gm6710
cell cycle progression
breast epithelium
Gene: Gm6710 (predicted gene 6710) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: Herpes simplex virus 1 infection - Mus musculus (mouse) UniProt: Q8C1K5, A2ART0, A2ARX2, A2ARX1 Entrez ID: 626832
Does Knockout of Atp6v0e2 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Atp6v0e2
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Atp6v0e2 (ATPase, H+ transporting, lysosomal V0 subunit E2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transport, proton transmembrane transport, synaptic vesicle lumen acidification, transmembrane transport; MF: proton-transporting ATPase activi...
Does Knockout of Htr4 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,481
Knockout
Htr4
protein/peptide accumulation
Regulatory T cell
Gene: Htr4 (5 hydroxytryptamine (serotonin) receptor 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-activating ...
Does Knockout of Apoc3 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Apoc3
protein/peptide distribution
myoblast cell line
Gene: Apoc3 (apolipoprotein C-III) Type: protein-coding Summary: This gene encodes an apolipoprotein which is the major protein component of very-low-density lipoproteins (VLDL) and a minor component of high-density lipoproteins (HDL). The encoded protein is thought to regulate the metabolism of triglyc...