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Does Knockout of Acot8 in Melanoma Cell Line causally result in cell proliferation?
0
2,488
Knockout
Acot8
cell proliferation
Melanoma Cell Line
Gene: Acot8 (acyl-CoA thioesterase 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acyl-CoA metabolic process, alpha-linolenic acid metabolic process, dicarboxylic acid catabolic process, fatty acid catabolic process, fatty acid derivative biosynthetic process, fatty a...
Does Knockout of Mir7087 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Mir7087
response to chemicals
Pancreatic Cancer Cell Line
Gene: Mir7087 (microRNA 7087) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Ago3 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Ago3
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Ago3 (argonaute RISC catalytic subunit 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RISC complex assembly, mRNA catabolic process, miRNA processing, miRNA-mediated gene silencing by inhibition of translation, miRNA-mediated gene silencing by mRNA destabilizati...
Does Knockout of Sirt6 in Lymphoma Cell Line causally result in response to chemicals?
0
1,546
Knockout
Sirt6
response to chemicals
Lymphoma Cell Line
Gene: Sirt6 (sirtuin 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, Ras protein signal transduction, base-excision repair, cardiac muscle cell differentiation, cellular response to angiotensin...
Does Knockout of Bcl6 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Bcl6
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Bcl6 (B cell leukemia/lymphoma 6) Type: protein-coding Summary: Enables DNA binding activity and DNA-binding transcription repressor activity, RNA polymerase II-specific. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including ...
Does Knockout of Scgb1b7 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Scgb1b7
protein/peptide accumulation
Embryonic Cell Line
Gene: Scgb1b7 (secretoglobin, family 1B, member 7) Type: protein-coding Summary: Predicted to enable steroid binding activity. Predicted to be active in extracellular region. [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: MF: molecular_function, steroid binding; CC: extrace...
Does Knockout of Ctxn3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,279
Knockout
Ctxn3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ctxn3 (cortexin 3) Type: protein-coding Summary: Predicted to be located in membrane. Is expressed in genitourinary system and otocyst. Orthologous to human CTXN3 (cortexin 3). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: CC: cellular_component, membrane Pa...
Does Knockout of Gns in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Gns
protein/peptide accumulation
Mouse cell
Gene: Gns (glucosamine (N-acetyl)-6-sulfatase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glycosaminoglycan metabolic process, heparan sulfate proteoglycan catabolic process, keratan sulfate proteoglycan catabolic process; MF: N-acetylglucosamine-6-sulfatase activity...
Does Knockout of Dnaja1 in Melanoma Cell Line causally result in protein/peptide accumulation?
0
1,839
Knockout
Dnaja1
protein/peptide accumulation
Melanoma Cell Line
Gene: Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1) Type: protein-coding Summary: The protein encoded by this gene is a member of the DnaJ family, whose members act as cochaperones of heat shock protein 70. Heat shock proteins facilitate protein folding, trafficking, prevention of aggregatio...
Does Knockout of Was in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Was
response to bacteria
renal medulla cell line
Gene: Was (Wiskott-Aldrich syndrome) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Cdc42 protein signal transduction, T cell activation, actin filament organization, actin filament polymerization, actin filament-based movement, actin polymerization or depolymerization, ...
Does Knockout of Rxfp2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,261
Knockout
Rxfp2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Rxfp2 (relaxin/insulin-like family peptide receptor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenylate cyclase-inhibiting G protein-cou...
Does Knockout of Pstpip2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,308
Knockout
Pstpip2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Pstpip2 (proline-serine-threonine phosphatase-interacting protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: actin binding, protein binding; CC: cytoplasm, cytoskeleton, cytosol, membrane, plasma membrane Pathways: UniProt: Q99M15 ...
Does Knockout of Asb2 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Asb2
response to virus
Microglial Cell Line
Gene: Asb2 (ankyrin repeat and SOCS box-containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, cardiac muscle cell development, cardiac muscle cell differentiation, dendritic cell migration, heart development, heart looping, intrace...
Does Knockout of Cdk9 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Cdk9
cell viability
Immortal mouse chromaffin cells
Gene: Cdk9 (cyclin dependent kinase 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, cellular response to cytokine stimulus, host-mediated activation of viral transcription, negative regulation of protein localization to chromatin, negat...
Does Knockout of 4931400O07Rik in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
4931400O07Rik
cell proliferation
Colonic Cancer Cell Line
Gene: 4931400O07Rik (RIKEN cDNA 4931400O07 gene) Type: ncRNA Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 70936
Does Knockout of Utp4 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Utp4
cell proliferation
Regulatory T cell
Gene: Utp4 (UTP4 small subunit processome component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of SSU-rRNA, maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), rRNA processing, regulation of DNA-templated transcriptio...
Does Knockout of Dph7 in Regulatory T cell causally result in cell proliferation?
0
1,483
Knockout
Dph7
cell proliferation
Regulatory T cell
Gene: Dph7 (diphthamine biosynethesis 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein histidyl modification to diphthamide; MF: diphthine methylesterase activity, hydrolase activity, molecular_function, protein methylesterase activity; CC: cellular_component, c...
Does Knockout of Mfn1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,262
Knockout
Mfn1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Mfn1 (mitofusin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GTP metabolic process, intracellular distribution of mitochondria, mitochondrial fusion, mitochondrion localization, mitochondrion organization, negative regulation of mitochondrial fission, positive...
Does Knockout of Pex12 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,286
Knockout
Pex12
cell proliferation
Mouse kidney carcinoma cell
Gene: Pex12 (peroxisomal biogenesis factor 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to reactive oxygen species, peroxisome organization, pexophagy, protein import into peroxisome matrix, protein import into peroxisome matrix, receptor recyclin...
Does Knockout of Wdfy1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Wdfy1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Wdfy1 (WD repeat and FYVE domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of toll-like receptor 3 signaling pathway, positive regulation of toll-like receptor 4 signaling pathway; MF: 1-phosphatidylinositol binding, metal ion...
Does Knockout of Card10 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Card10
protein/peptide accumulation
Embryonic Cell Line
Gene: Card10 (caspase recruitment domain family, member 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: activation of NF-kappaB-inducing kinase activity, negative regulation of cell migration involved in sprouting angiogenesis, positive regulation of canonical NF-kapp...
Does Knockout of Rorb in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Rorb
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rorb (RAR-related orphan receptor beta) Type: protein-coding Summary: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to e...
Does Knockout of Dnase1l2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Dnase1l2
protein/peptide accumulation
Embryonic Cell Line
Gene: Dnase1l2 (deoxyribonuclease 1-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA catabolic process, corneocyte development, hair follicle development; MF: DNA binding, DNA nuclease activity, catalytic activity, deoxyribonuclease I activity, endonuclease act...
Does Knockout of Slc2a5 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Slc2a5
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Slc2a5 (solute carrier family 2 (facilitated glucose transporter), member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-glucose import, D-glucose transmembrane transport, cellular response to fructose stimulus, dehydroascorbic acid transport, fructose import ...
Does Knockout of Glis3 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Glis3
phagocytosis
macrophage
Gene: Glis3 (GLIS family zinc finger 3) Type: protein-coding Summary: This gene is a member of the GLI-similar zinc finger protein family and encodes a nuclear protein which contains multiple C2H2-type zinc finger domains. This protein functions as both a repressor and activator of transcription and is ...
Does Knockout of Zfp472 in macrophage causally result in phagocytosis?
0
1,890
Knockout
Zfp472
phagocytosis
macrophage
Gene: Zfp472 (zinc finger protein 472) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Pde4c in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Pde4c
cell proliferation
Colonic Cancer Cell Line
Gene: Pde4c (phosphodiesterase 4C, cAMP specific) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cAMP catabolic process, negative regulation of cAMP/PKA signal transduction, negative regulation of insulin secretion involved in cellular response to glucose stimulus, signa...
Does Knockout of Ell2 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Ell2
protein/peptide distribution
myoblast cell line
Gene: Ell2 (elongation factor for RNA polymerase II 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of transcription elongation by RNA polymerase II, snRNA transcription by RNA polymerase II, transcription elongation by RNA polymerase II; CC: nucleo...
Does Knockout of 4930558K02Rik in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
4930558K02Rik
cell proliferation
Colonic Cancer Cell Line
Gene: 4930558K02Rik (RIKEN cDNA 4930558K02 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: E0CXC6 Entrez ID: 75368
Does Knockout of Slc5a11 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,178
Knockout
Slc5a11
tumorigenicity
Colonic Cancer Cell Line
Gene: Slc5a11 (solute carrier family 5 (sodium/glucose cotransporter), member 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, carbohydrate transmembrane transport, hexose transmembrane transport, monoatomic ion transport, myo-inositol transport, sod...
Does Knockout of Cep104 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Cep104
cell proliferation
Mouse kidney carcinoma cell
Gene: Cep104 (centrosomal protein 104) Type: protein-coding Summary: No summary available. Gene Ontology: MF: glutamate binding, glycine binding, molecular_function, protein binding, thienylcyclohexylpiperidine binding; CC: cell projection, centriole, centrosome, cilium, cytoplasm, cytoskeleton...
Does Knockout of Pqbp1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Pqbp1
cell proliferation
Colonic Cancer Cell Line
Gene: Pqbp1 (polyglutamine binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, activation of innate immune response, alternative mRNA splicing, via spliceosome, cellular response to exogenous dsRNA, defense response to virus, immune system pro...
Does Knockout of Rhobtb1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Rhobtb1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rhobtb1 (Rho-related BTB domain containing 1) Type: protein-coding Summary: Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including cytoskeleton organization; regulation of actin cytoskeleton organizat...
Does Knockout of Rasgrp3 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Rasgrp3
protein/peptide distribution
myoblast cell line
Gene: Rasgrp3 (RAS, guanyl releasing protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Ras protein signal transduction, immune response, small GTPase-mediated signal transduction; MF: GTPase activator activity, calcium ion binding, guanyl-nucleotide exchange fact...
Does Knockout of Krtap6-1 in Melanoma Cell Line causally result in cell proliferation?
0
1,838
Knockout
Krtap6-1
cell proliferation
Melanoma Cell Line
Gene: Krtap6-1 (keratin associated protein 6-1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, keratinization; MF: identical protein binding, molecular_function; CC: cellular_component, intermediate filament Pathways: Developmental Biology, K...
Does Knockout of Fkbp14 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Fkbp14
cell proliferation
Mouse kidney carcinoma cell
Gene: Fkbp14 (FK506 binding protein 14) Type: protein-coding Summary: Predicted to enable RNA polymerase II CTD heptapeptide repeat P3 isomerase activity; RNA polymerase II CTD heptapeptide repeat P6 isomerase activity; and calcium ion binding activity. Predicted to be involved in regulation of transcri...
Does Knockout of Dstn in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,260
Knockout
Dstn
cell proliferation
Mouse kidney carcinoma cell
Gene: Dstn (destrin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament depolymerization, actin filament fragmentation, actin filament severing, cell motility, positive regulation of actin filament depolymerization; MF: actin binding, actin filament binding; C...
Does Knockout of Mrps18a in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Mrps18a
cell proliferation
Regulatory T cell
Gene: Mrps18a (mitochondrial ribosomal protein S18A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: small ribosomal subunit rRNA binding, structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large...
Does Knockout of Sel1l in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Sel1l
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sel1l (sel-1 suppressor of lin-12-like (C. elegans)) Type: protein-coding Summary: Involved in ERAD pathway; protein secretion; and triglyceride metabolic process. Acts upstream of or within response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum. Predicted to be...
Does Knockout of H2-M10.5 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
H2-M10.5
protein/peptide distribution
myoblast cell line
Gene: H2-M10.5 (histocompatibility 2, M region locus 10.5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent, antigen processing and presentation of endogenous ...
Does Knockout of Eed in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Eed
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Eed (embryonic ectoderm development) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to leukemia inhibitory factor, chromatin organization, facultative heterochromatin formation, genomic imprinting, heterochromatin formation, negative regulation of...
Does Knockout of Cyp2d40 in myoblast cell line causally result in protein/peptide distribution?
1
1,683
Knockout
Cyp2d40
protein/peptide distribution
myoblast cell line
Gene: Cyp2d40 (cytochrome P450, family 2, subfamily d, polypeptide 40) Type: protein-coding Summary: No summary available. Gene Ontology: MF: anandamide 11,12 epoxidase activity, anandamide 14,15 epoxidase activity, anandamide 8,9 epoxidase activity, aromatase activity, heme binding, iron ion b...
Does Knockout of Ankrd61 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Ankrd61
cell proliferation
Embryonic Stem Cell Line
Gene: Ankrd61 (ankyrin repeat domain 61) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, molecular_function; CC: nucleoplasm Pathways: UniProt: Q9CQM6 Entrez ID: 66729
Does Knockout of Shd in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Shd
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Shd (src homology 2 domain-containing transforming protein D) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: O88834 Entrez ID: 20420
Does Knockout of Med26 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Med26
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Med26 (mediator complex subunit 26) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, positive regulation of gene expression, positive regulation of transcription elongation by RNA polymerase II, positive regulation of...
Does Knockout of Sptlc3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Sptlc3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sptlc3 (serine palmitoyltransferase, long chain base subunit 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ceramide biosynthetic process, lipid metabolic process, sphingoid biosynthetic process, sphingolipid metabolic process, sphingosine biosynthetic process; ...
Does Knockout of Acer2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Acer2
cell proliferation
Mouse kidney carcinoma cell
Gene: Acer2 (alkaline ceramidase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA damage response, signal transduction by p53 class mediator, cellular response to xenobiotic stimulus, ceramide catabolic process, ceramide metabolic process, lipid...
Does Knockout of Zfp105 in pro-B-lymphocyte causally result in response to chemicals?
0
1,720
Knockout
Zfp105
response to chemicals
pro-B-lymphocyte
Gene: Zfp105 (zinc finger protein 105) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II transcription regulatory region sequence...
Does Knockout of Slc23a2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Slc23a2
cell proliferation
Mouse kidney carcinoma cell
Gene: Slc23a2 (solute carrier family 23 (nucleobase transporters), member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-ascorbic acid metabolic process, L-ascorbic acid transmembrane transport, blood circulation, cell adhesion, cellular response to ethanol, monoato...
Does Knockout of Sftpc in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Sftpc
cell proliferation
Melanoma Cell Line
Gene: Sftpc (surfactant associated protein C) Type: protein-coding Summary: No summary available. Gene Ontology: CC: alveolar lamellar body, cytoplasm, extracellular region, extracellular space, multivesicular body Pathways: UniProt: Q6P8P8 Entrez ID: 20389
Does Knockout of Gzmn in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Gzmn
cell cycle progression
breast epithelium
Gene: Gzmn (granzyme N) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein maturation, proteolysis; MF: hydrolase activity, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity; CC: cytolytic granule, cytoplasm, extracellular space ...
Does Knockout of G6pd2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
G6pd2
cell proliferation
Mouse kidney carcinoma cell
Gene: G6pd2 (glucose-6-phosphate dehydrogenase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NADP+ metabolic process, NADPH regeneration, cellular response to oxidative stress, cholesterol biosynthetic process, erythrocyte maturation, glucose 6-phosphate metabolic pr...
Does Knockout of 4930510E17Rik in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
4930510E17Rik
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: 4930510E17Rik (RIKEN cDNA 4930510E17 gene) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Fundc1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Fundc1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Fundc1 (FUN14 domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagy, autophagy of mitochondrion, mitochondrial fusion, mitophagy, response to hypoxia; CC: membrane, mitochondrial outer membrane, mitochondrion Pathways: Autophagy, Ma...
Does Knockout of Kctd2 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,177
Knockout
Kctd2
tumorigenicity
Colonic Cancer Cell Line
Gene: Kctd2 (potassium channel tetramerisation domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, protein homooligomerization; MF: cullin family protein binding, protein-containing comple...
Does Knockout of Scgb2b7 in myoblast cell line causally result in protein/peptide distribution?
0
1,683
Knockout
Scgb2b7
protein/peptide distribution
myoblast cell line
Gene: Scgb2b7 (secretoglobin, family 2B, member 7) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, extracellular region, extracellular space Pathways: UniProt: D3YYY1 Entrez ID: 100043836
Does Knockout of Spata7 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Spata7
cell proliferation
Colonic Cancer Cell Line
Gene: Spata7 (spermatogenesis associated 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule cytoskeleton organization, photoreceptor cell maintenance, protein localization to photoreceptor connecting cilium, protein localization to photoreceptor outer segment,...
Does Knockout of Iqgap1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Iqgap1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Iqgap1 (IQ motif containing GTPase activating protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, caveola assembly, cell migration, cellular response to calcium ion, cellular response to epidermal growth factor stimulus, cellular response to fib...
Does Knockout of Ifngr2 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,276
Knockout
Ifngr2
cell proliferation
Colonic Cancer Cell Line
Gene: Ifngr2 (interferon gamma receptor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytokine-mediated signaling pathway, defense response to virus, microglial cell activation, positive regulation of glutamate receptor signaling pathway, type II interferon-mediated ...
Does Knockout of Vmn2r45 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Vmn2r45
protein/peptide accumulation
Embryonic Cell Line
Gene: Vmn2r45 (vomeronasal 2, receptor 45) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: L7N2B...
Does Knockout of BC016579 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,260
Knockout
BC016579
cell proliferation
Mouse kidney carcinoma cell
Gene: BC016579 (cDNA sequence, BC016579) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, endoplasmic reticulum, endoplasmic reticulum membrane, membrane, plasma membrane Pathways: UniProt: Q8C5C9 Entrez ID: 212998
Does Knockout of Ccnb1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Ccnb1
protein/peptide accumulation
Embryonic Cell Line
Gene: Ccnb1 (cyclin B1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G1/S transition of mitotic cell cycle, cell division, cellular response to fatty acid, cellular response to hypoxia, cellular response to iron(III) ion, digestive tract development, in utero embryonic...
Does Knockout of Dcp1b in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Dcp1b
protein/peptide accumulation
Regulatory T cell
Gene: Dcp1b (decapping mRNA 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to interleukin-17, deadenylation-dependent decapping of nuclear-transcribed mRNA, deadenylation-independent decapping of nuclear-transcribed mRNA, nuclear-transcribed mRNA ca...
Does Knockout of Col3a1 in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Col3a1
cell proliferation
Melanoma Cell Line
Gene: Col3a1 (collagen, type III, alpha 1) Type: protein-coding Summary: This gene encodes the alpha-1 subunit of the fibril-forming type III collagen found in bone, cartilage, dentin, tendon, bone marrow stroma and other connective tissue. The encoded protein forms homotrimeric type III procollagen tha...
Does Knockout of Foxa2 in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Foxa2
cell cycle progression
breast epithelium
Gene: Foxa2 (forkhead box A2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, adult locomotory behavior, anatomical structure formation involved in morphogenesis, anatomical structure morphogenesis, anterior/posterior pattern specification, cell d...
Does Knockout of Nxph4 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Nxph4
protein/peptide distribution
myoblast cell line
Gene: Nxph4 (neurexophilin 4) Type: protein-coding Summary: Predicted to enable signaling receptor binding activity. Involved in modulation of chemical synaptic transmission. Is active in GABA-ergic synapse. Is expressed in brain and spinal cord lateral wall. Orthologous to human NXPH4 (neurexophilin 4)...
Does Knockout of Kif14 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Kif14
protein/peptide distribution
myoblast cell line
Gene: Kif14 (kinesin family member 14) Type: protein-coding Summary: Enables several functions, including ATP binding activity; ATP hydrolysis activity; and plus-end-directed microtubule motor activity. Involved in several processes, including brain development; negative regulation of neuron apoptotic p...
Does Knockout of Vrk1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Vrk1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Vrk1 (vaccinia related kinase 1) Type: protein-coding Summary: Enables protein serine/threonine kinase activity. Involved in regulation of neuron migration. Acts upstream of or within protein autophosphorylation. Located in nucleus. Is expressed in several structures, including dorsal mesogastrium...
Does Knockout of Rpl37a in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
685
Knockout
Rpl37a
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Rpl37a (ribosomal protein L37a) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, translation, translation at postsynapse, translation at presynapse; MF: large ribosomal subunit rRNA binding, metal ion binding, structural constituent of riboso...
Does Knockout of Rreb1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Rreb1
cell proliferation
Mouse kidney carcinoma cell
Gene: Rreb1 (ras responsive element binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, positive regulation of brown fat cell differentiation, pos...
Does Knockout of Ppp6r1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Ppp6r1
protein/peptide accumulation
Embryonic Cell Line
Gene: Ppp6r1 (protein phosphatase 6, regulatory subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: protein phosphatase binding, protein phosphatase regulator activity, small GTPase binding; CC: cytoplasm, cytosol, lamellipodium, nucleus Pathways: Asparagi...
Does Knockout of Cxcl1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Cxcl1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Cxcl1 (C-X-C motif chemokine ligand 1) Type: protein-coding Summary: This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein ...
Does Knockout of Zfp775 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Zfp775
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Zfp775 (zinc finger protein 775) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding, metal ion binding, zinc ion bi...
Does Knockout of Sec24b in macrophage causally result in phagocytosis?
0
1,890
Knockout
Sec24b
phagocytosis
macrophage
Gene: Sec24b (SEC24 homolog B, COPII coat complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: COPII-coated vesicle cargo loading, aorta morphogenesis, auditory receptor cell morphogenesis, auditory receptor cell stereocilium organization, circulatory system...
Does Knockout of Nlrc4 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Nlrc4
response to virus
Embryonic Fibroblast Cell Line
Gene: Nlrc4 (NLR family, CARD domain containing 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: activation of innate immune response, apoptotic process, defense response to bacterium, detection of bacterium, immune system process, inflammatory response, innate immune r...
Does Knockout of Rae1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Rae1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Rae1 (ribonucleic acid export 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA export from nucleus, cell division, nucleocytoplasmic transport, regulation of mitotic spindle organization, transcription-dependent tethering of RNA polymerase II gene DNA at nucle...
Does Knockout of Syde2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Syde2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Syde2 (synapse defective 1, Rho GTPase, homolog 2 (C. elegans)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell migration, regulation of Ras protein signal transduction Pathways: RAC1 GTPase cycle, RHO GTPase cycle, Signal Transduction, Signaling by Rh...
Does Knockout of Grtp1 in myoblast cell line causally result in protein/peptide distribution?
0
1,683
Knockout
Grtp1
protein/peptide distribution
myoblast cell line
Gene: Grtp1 (GH regulated TBC protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: GTPase activator activity; CC: cytoplasm, plasma membrane Pathways: UniProt: Q9D3N8 Entrez ID: 66790
Does Knockout of Chrna7 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Chrna7
cell proliferation
Mouse kidney carcinoma cell
Gene: Chrna7 (cholinergic receptor, nicotinic, alpha polypeptide 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation, T cell activation, acetylcholine receptor signaling pathway, associative learning, behavioral response to ethanol, behavioral response to...
Does Knockout of Pet100 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Pet100
cell proliferation
Mouse kidney carcinoma cell
Gene: Pet100 (PET100 homolog) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial cytochrome c oxidase assembly; CC: membrane, mitochondrial inner membrane, mitochondrion Pathways: UniProt: P0DJE0 Entrez ID: 100503890
Does Knockout of Dydc2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
1,565
Knockout
Dydc2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Dydc2 (DPY30 domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9D3X8 Entrez ID: 71200
Does Knockout of Adgra3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,268
Knockout
Adgra3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Adgra3 (adhesion G protein-coupled receptor A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, cell surface receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity, transmembrane signali...
Does Knockout of Atl3 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Atl3
cell cycle progression
breast epithelium
Gene: Atl3 (atlastin GTPase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, cellular response to type II interferon, endoplasmic reticulum membrane fusion, endoplasmic reticulum organization, endoplasmic reticulum tubular network membrane organizati...
Does Knockout of Gm3409 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Gm3409
response to virus
Embryonic Fibroblast Cell Line
Gene: Gm3409 (predicted gene 3409) Type: protein-coding Summary: No summary available. Gene Ontology: MF: guanyl-nucleotide exchange factor activity, molecular_function Pathways: UniProt: A0A0G2JE67, L7N464, D3YYA7 Entrez ID: 100041566
Does Knockout of Litaf in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Litaf
cell proliferation
Regulatory T cell
Gene: Litaf (LPS-induced TN factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to lipopolysaccharide, negative regulation of non-canonical NF-kappaB signal transduction, positive regulation of canonical NF-kappaB signal transduction, positive regula...
Does Knockout of Ttf2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,263
Knockout
Ttf2
cell proliferation
Colonic Cancer Cell Line
Gene: Ttf2 (transcription termination factor, RNA polymerase II) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair, DNA-templated transcription termination, RNA splicing, biological_process, mRNA processing; MF: ATP binding, ATP-dependent activity, acting on DNA,...
Does Knockout of Saa4 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Saa4
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Saa4 (serum amyloid A 4) Type: protein-coding Summary: No summary available. Gene Ontology: CC: extracellular region, high-density lipoprotein particle Pathways: UniProt: P31532 Entrez ID: 20211
Does Knockout of Pcdh17 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Pcdh17
protein/peptide distribution
myoblast cell line
Gene: Pcdh17 (protocadherin 17) Type: protein-coding Summary: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein contains six extracellular cadherin domains, a transmembrane domain, and a cytoplasmic tail differing from those of the classical...
Does Knockout of Trip10 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Trip10
phagocytosis
macrophage
Gene: Trip10 (thyroid hormone receptor interactor 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endocytosis, epithelial to mesenchymal transition, negative regulation of cardiac muscle cell apoptotic process, positive regulation of cell growth involved in cardiac mu...
Does Knockout of Cstl1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Cstl1
protein/peptide accumulation
Regulatory T cell
Gene: Cstl1 (cystatin-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled opioid receptor signaling pathway, signaling receptor ligand precursor processing, transmission of nerve impulse; MF: cysteine-type endopeptidase inhibitor activity, cysteine-t...
Does Knockout of Vps9d1 in Melanoma Cell Line causally result in cell proliferation?
0
1,838
Knockout
Vps9d1
cell proliferation
Melanoma Cell Line
Gene: Vps9d1 (VPS9 domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, vesicle-mediated transport; MF: guanyl-nucleotide exchange factor activity, identical protein binding, molecular_function, small GTPase binding; CC: cytosol, endocy...
Does Knockout of Alg6 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Alg6
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Alg6 (ALG6 alpha-1,3-glucosyltransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: dolichol-linked oligosaccharide biosynthetic process, protein N-linked glycosylation, protein glycosylation; MF: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferas...
Does Knockout of Wfdc12 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Wfdc12
cell proliferation
Mouse kidney carcinoma cell
Gene: Wfdc12 (WAP four-disulfide core domain 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, defense response to bacterium, innate immune response; MF: peptidase inhibitor activity, serine-type endopeptidase inhibitor activity; CC: extr...
Does Knockout of Gps1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Gps1
cell proliferation
Mouse kidney carcinoma cell
Gene: Gps1 (G protein pathway suppressor 1) Type: protein-coding Summary: Predicted to be involved in protein deneddylation. Part of COP9 signalosome. Is expressed in several structures, including adrenal gland; central nervous system; genitourinary system; hemolymphoid system gland; and retina. Ortholo...
Does Knockout of Kcnc1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Kcnc1
cell proliferation
Colonic Cancer Cell Line
Gene: Kcnc1 (potassium voltage gated channel, Shaw-related subfamily, member 1) Type: protein-coding Summary: Enables kinesin binding activity and transmembrane transporter binding activity. Predicted to be involved in several processes, including positive regulation of potassium ion transmembrane trans...
Does Knockout of Rimbp2 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Rimbp2
response to virus
Microglial Cell Line
Gene: Rimbp2 (RIMS binding protein 2) Type: protein-coding Summary: Enables voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels and voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential. A structural const...
Does Knockout of Ppcs in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,170
Knockout
Ppcs
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ppcs (phosphopantothenoylcysteine synthetase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acetyl-CoA biosynthetic process, coenzyme A biosynthetic process, heart process; MF: ATP binding, identical protein binding, ligase activity, nucleotide binding, phosphopan...
Does Knockout of Slc1a7 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Slc1a7
protein/peptide accumulation
Regulatory T cell
Gene: Slc1a7 (solute carrier family 1 (glutamate transporter), member 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-glutamate transmembrane transport, chloride transmembrane transport, excitatory postsynaptic potential, monoatomic anion transmembrane transport, neu...
Does Knockout of Zdhhc20 in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Zdhhc20
cell proliferation
Melanoma Cell Line
Gene: Zdhhc20 (zinc finger, DHHC domain containing 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: host-mediated activation of viral process, peptidyl-L-cysteine S-palmitoylation, protein palmitoylation, protein targeting to membrane, synaptic vesicle maturation, viri...
Does Knockout of Trmt112 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Trmt112
cell proliferation
Mouse kidney carcinoma cell
Gene: Trmt112 (tRNA methyltransferase 11-2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of LSU-rRNA, maturation of SSU-rRNA, peptidyl-glutamine methylation, positive regulation of rRNA processing, rRNA (guanine-N7)-methylation, rRNA methylation, tRNA methyl...