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Does Knockout of Ncam2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,277
Knockout
Ncam2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ncam2 (neural cell adhesion molecule 2) Type: protein-coding Summary: Predicted to enable identical protein binding activity. Predicted to be involved in axonal fasciculation and cell adhesion. Located in axon. Is active in synaptic membrane. Is expressed in several structures, including alimentar...
Does Knockout of Gzmm in Melanoma Cell Line causally result in cell proliferation?
0
1,281
Knockout
Gzmm
cell proliferation
Melanoma Cell Line
Gene: Gzmm (granzyme M (lymphocyte met-ase 1)) Type: protein-coding Summary: The protein encoded by this gene is a member of a family of cytotoxic lymphocyte serine proteases called granzymes, which are expressed by cytotoxic T lymphocytes and natural killer cells. This protein belongs to a subfamily of...
Does Knockout of Dad1 in Embryonic Fibroblast Cell Line causally result in cell proliferation?
1
1,716
Knockout
Dad1
cell proliferation
Embryonic Fibroblast Cell Line
Gene: Dad1 (defender against cell death 1) Type: protein-coding Summary: Predicted to enable enzyme activator activity. Acts upstream of or within blastocyst development and negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of oligo...
Does Knockout of Sftpc in Regulatory T cell causally result in protein/peptide accumulation?
0
1,481
Knockout
Sftpc
protein/peptide accumulation
Regulatory T cell
Gene: Sftpc (surfactant associated protein C) Type: protein-coding Summary: No summary available. Gene Ontology: CC: alveolar lamellar body, cytoplasm, extracellular region, extracellular space, multivesicular body Pathways: UniProt: Q6P8P8 Entrez ID: 20389
Does Knockout of Col7a1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Col7a1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Col7a1 (collagen, type VII, alpha 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, collagen fibril organization; MF: extracellular matrix structural constituent conferring tensile strength, identical protein binding, peptidase inhibitor activity, se...
Does Knockout of Btbd3 in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Btbd3
cell proliferation
Regulatory T cell
Gene: Btbd3 (BTB domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cerebral cortex development, dendrite morphogenesis, nervous system development, neurogenesis; CC: cytoplasm, cytosol, nucleus Pathways: UniProt: P58545 Entrez...
Does Knockout of Inpp4a in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Inpp4a
cell proliferation
Colonic Cancer Cell Line
Gene: Inpp4a (inositol polyphosphate-4-phosphatase, type I) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid metabolic process, phosphatidylinositol biosynthetic process, phosphatidylinositol-3-phosphate biosynthetic process, polyphosphate catabolic process, regulati...
Does Knockout of Adgrf3 in myoblast cell line causally result in protein/peptide distribution?
0
1,683
Knockout
Adgrf3
protein/peptide distribution
myoblast cell line
Gene: Adgrf3 (adhesion G protein-coupled receptor F3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, cell surface receptor signaling pathway, signal t...
Does Knockout of Prss21 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Prss21
cell proliferation
Mouse kidney carcinoma cell
Gene: Prss21 (serine protease 21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteolysis, spermatogenesis; MF: hydrolase activity, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity; CC: extracellular space, membrane, plasma membra...
Does Knockout of Vps33a in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Vps33a
cell proliferation
Colonic Cancer Cell Line
Gene: Vps33a (VPS33A CORVET/HOPS core subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome maturation, autophagy, endosome to lysosome transport, intracellular protein transport, lysosome localization, melanosome localization, pigmentation, platelet form...
Does Knockout of Irf4 in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Irf4
cell proliferation
Melanoma Cell Line
Gene: Irf4 (interferon regulatory factor 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T-helper 17 cell lineage commitment, chromatin remodeling, defense response to protozoan, dendritic cell differentiation, immune system process, lymphocyte activation involved in i...
Does Knockout of Sema3b in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,277
Knockout
Sema3b
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Sema3b (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B) Type: protein-coding Summary: This gene encodes a secreted protein that belongs to the class 3 semaphorin/collapsin family. Members of this family play a role in growth cone guidance during neurogenesis...
Does Knockout of Syt7 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Syt7
cell proliferation
Colonic Cancer Cell Line
Gene: Syt7 (synaptotagmin VII) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion regulated lysosome exocytosis, calcium ion-regulated exocytosis of neurotransmitter, calcium-dependent activation of synaptic vesicle fusion, calcium-ion regulated exocytosis, exocy...
Does Knockout of Tmem87a in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Tmem87a
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Tmem87a (transmembrane protein 87A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to mechanical stimulus, detection of mechanical stimulus involved in sensory perception of touch, retrograde transport, endosome to Golgi; CC: Golgi apparatus, Golg...
Does Knockout of Spin1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Spin1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Spin1 (spindlin 1) Type: protein-coding Summary: Enables histone reader activity and methylated histone binding activity. Involved in protein localization to chromatin and transposable element silencing by piRNA-mediated DNA methylation. Located in spindle. Is active in chromatin. Is expressed in ...
Does Knockout of Rnf145 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,481
Knockout
Rnf145
protein/peptide accumulation
Regulatory T cell
Gene: Rnf145 (ring finger protein 145) Type: protein-coding Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in ERAD pathway and proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted...
Does Knockout of Vax1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Vax1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Vax1 (ventral anterior homeobox 1) Type: protein-coding Summary: This gene encodes a member of the EMX homeobox protein family. The encoded protein functions as a transcription factor which is important in the development of anterior ventral forebrain and visual system. Disruption of this gene cau...
Does Knockout of Tmem101 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,259
Knockout
Tmem101
cell proliferation
Mouse kidney carcinoma cell
Gene: Tmem101 (transmembrane protein 101) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q91VP7 Entrez ID: 76547
Does Knockout of Vmn2r115 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
163
Knockout
Vmn2r115
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Vmn2r115 (vomeronasal 2, receptor 115) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: A0A...
Does Knockout of Ptpra in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Ptpra
cell cycle progression
breast epithelium
Gene: Ptpra (protein tyrosine phosphatase receptor type A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: insulin receptor signaling pathway, integrin-mediated signaling pathway, modulation of chemical synaptic transmission, positive regulation of oligodendrocyte differe...
Does Knockout of Dnajc15 in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
0
2,474
Knockout
Dnajc15
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Dnajc15 (DnaJ heat shock protein family (Hsp40) member C15) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to starvation, negative regulation of mitochondrial electron transport, NADH to ubiquinone, negative regulation of protein-containing comple...
Does Knockout of Ndor1 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Ndor1
cell proliferation
Colonic Cancer Cell Line
Gene: Ndor1 (NADPH dependent diflavin oxidoreductase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: electron transport chain, iron-sulfur cluster assembly; MF: FAD binding, FMN binding, NADP binding, NADPH binding, NADPH-hemoprotein reductase activity, NADPH-iron-sulf...
Does Knockout of P3h2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
P3h2
protein/peptide accumulation
Embryonic Cell Line
Gene: P3h2 (prolyl 3-hydroxylase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: collagen metabolic process, negative regulation of cell population proliferation, peptidyl-proline hydroxylation; MF: L-ascorbic acid binding, dioxygenase activity, iron ion binding, metal...
Does Knockout of Ak6 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Ak6
cell proliferation
Colonic Cancer Cell Line
Gene: Ak6 (adenylate kinase 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nucleoside monophosphate phosphorylation, rRNA processing, ribosomal small subunit biogenesis, ribosome biogenesis; MF: AMP kinase activity, ATP binding, ATP hydrolysis activity, kinase activit...
Does Knockout of Kitl in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,277
Knockout
Kitl
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Kitl (kit ligand) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, cell adhesion, developmental process involved in reproduction, ectopic germ cell programmed cell death, embryonic hemopoiesis, extrinsic apoptotic signaling pathway in absenc...
Does Knockout of Arap1 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Arap1
cell proliferation
Melanoma Cell Line
Gene: Arap1 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of stress fiber assembly, photoreceptor cell maintenance, positive regulation of DNA-templated transcription, positive regulation of...
Does Knockout of Npy5r in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,178
Knockout
Npy5r
tumorigenicity
Colonic Cancer Cell Line
Gene: Npy5r (neuropeptide Y receptor Y5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, cardiac left ventricle morphogenesis, chemical synaptic transmission, eating behavior, generation of ovulation cycle rhythm, negative reg...
Does Knockout of Gtpbp4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Gtpbp4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gtpbp4 (GTP binding protein 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), negative regulation of DNA replication, negative regulation of G2/M transition of mitotic cell cy...
Does Knockout of Trim39 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Trim39
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Trim39 (tripartite motif-containing 39) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, innate immune response, mitotic G2 DNA damage checkpoint signaling, negative regulation of canonical NF-kappaB signal transduction, negative regulation of prot...
Does Knockout of Trim55 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Trim55
cell proliferation
Colonic Cancer Cell Line
Gene: Trim55 (tripartite motif-containing 55) Type: protein-coding Summary: No summary available. Gene Ontology: BP: canonical NF-kappaB signal transduction, cellular response to lipopolysaccharide, defense response to virus, diapedesis, inflammatory response, innate immune response, leukocyte ...
Does Knockout of Inpp1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,170
Knockout
Inpp1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Inpp1 (inositol polyphosphate-1-phosphatase) Type: protein-coding Summary: No summary available. Gene Ontology: MF: hydrolase activity, inositol-1,3,4-trisphosphate 1-phosphatase activity, inositol-1,4-bisphosphate 1-phosphatase activity, metal ion binding Pathways: D-<i>myo</i>-...
Does Knockout of Zfp966 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Zfp966
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Zfp966 (zinc finger protein 966) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA-binding transcription factor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding Pathways: UniProt: A2ART2, A2ART1, E9PXD4, A0A571BD11...
Does Knockout of Ccdc89 in myoblast cell line causally result in protein/peptide distribution?
0
1,685
Knockout
Ccdc89
protein/peptide distribution
myoblast cell line
Gene: Ccdc89 (coiled-coil domain containing 89) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, nucleus Pathways: UniProt: Q9DA73 Entrez ID: 70054
Does Knockout of Mir7233 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Mir7233
response to virus
Embryonic Fibroblast Cell Line
Gene: Mir7233 (microRNA 7233) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Bloc1s1 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Bloc1s1
phagocytosis
macrophage
Gene: Bloc1s1 (biogenesis of lysosomal organelles complex-1, subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aerobic respiration, anterograde axonal transport, anterograde synaptic vesicle transport, endosomal transport, lysosome localization, melanosome organi...
Does Knockout of Fam180a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Fam180a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Fam180a (family with sequence similarity 180, member A) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, extracellular region Pathways: UniProt: Q8BR21 Entrez ID: 208164
Does Knockout of Npr1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,268
Knockout
Npr1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Npr1 (natriuretic peptide receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blood vessel diameter maintenance, cGMP biosynthetic process, cGMP-mediated signaling, cell surface receptor signaling pathway, cyclic nucleotide biosynthetic process, dopamine met...
Does Knockout of Tcf7 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Tcf7
response to virus
Neuroblastoma Cell Line
Gene: Tcf7 (transcription factor 7, T cell specific) Type: protein-coding Summary: This gene encodes a transcription factor which is a member of the T-cell specific transcription factor family. The encoded protein is distinct from the hepatic transcription factor, transcription factor 1, which is also r...
Does Knockout of Hmx1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Hmx1
cell proliferation
Embryonic Stem Cell Line
Gene: Hmx1 (H6 homeobox 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by RNA polymera...
Does Knockout of Slc34a1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Slc34a1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Slc34a1 (solute carrier family 34 (sodium phosphate), member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: arsenate ion transmembrane transport, bone remodeling, calcium ion homeostasis, cellular response to phosphate starvation, gene expression, inorganic diph...
Does Knockout of Pld3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Pld3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Pld3 (phospholipase D family member 3) Type: protein-coding Summary: Enables single-stranded DNA 5'-3' DNA exonuclease activity. Involved in regulation of cytokine production involved in inflammatory response. Located in late endosome membrane and lysosomal membrane. Is expressed in several struct...
Does Knockout of Samd12 in Melanoma Cell Line causally result in protein/peptide accumulation?
0
1,839
Knockout
Samd12
protein/peptide accumulation
Melanoma Cell Line
Gene: Samd12 (sterile alpha motif domain containing 12) Type: protein-coding Summary: Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be active in cytoplasmic side of plasma membrane. Human ortholog(s) of this gene implicated in familial adult my...
Does Knockout of Iqsec1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Iqsec1
protein/peptide accumulation
Embryonic Cell Line
Gene: Iqsec1 (IQ motif and Sec7 domain 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, dendritic spine development, positive regulation of focal adhesion disassembly, positive regulation of keratinocyte migration, positive regulation of...
Does Knockout of Dse in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Dse
protein/peptide accumulation
Embryonic Cell Line
Gene: Dse (dermatan sulfate epimerase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chondroitin sulfate proteoglycan metabolic process, dermatan sulfate proteoglycan biosynthetic process, dermatan sulfate proteoglycan metabolic process, heparan sulfate proteoglycan bio...
Does Knockout of Ttll5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Ttll5
cell proliferation
Mouse kidney carcinoma cell
Gene: Ttll5 (tubulin tyrosine ligase-like family, member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fertilization, flagellated sperm motility, retina development in camera-type eye, sperm axoneme assembly, spermatogenesis; MF: ATP binding, ligase activity, metal i...
Does Knockout of Wbp1l in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Wbp1l
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Wbp1l (WW domain binding protein 1 like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CXCL12-activated CXCR4 signaling pathway, hemopoiesis, positive regulation of protein ubiquitination; CC: cellular_component, membrane Pathways: UniProt: Q8BG...
Does Knockout of Me3 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Me3
response to virus
Embryonic Fibroblast Cell Line
Gene: Me3 (malic enzyme 3, NADP(+)-dependent, mitochondrial) Type: protein-coding Summary: No summary available. Gene Ontology: BP: malate metabolic process, pyruvate biosynthetic process, pyruvate metabolic process; MF: NAD binding, NADP+ binding, malate dehydrogenase (decarboxylating) (NADP+)...
Does Knockout of Slc38a8 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Slc38a8
response to virus
Microglial Cell Line
Gene: Slc38a8 (solute carrier family 38, member 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-alpha-amino acid transmembrane transport, amino acid transmembrane transport, amino acid transport, aspartate metabolic process, neuron projection development, optic nerve...
Does Knockout of Vps9d1 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Vps9d1
response to virus
Embryonic Fibroblast Cell Line
Gene: Vps9d1 (VPS9 domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, vesicle-mediated transport; MF: guanyl-nucleotide exchange factor activity, identical protein binding, molecular_function, small GTPase binding; CC: cytosol, endocy...
Does Knockout of Vegfd in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Vegfd
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Vegfd (vascular endothelial growth factor D) Type: protein-coding Summary: This gene encodes a member of the vascular endothelial growth factor (VEGF) family that acts as a ligand for vascular endothelial growth factor receptor 3. Signalling through this protein is important for growth and develop...
Does Knockout of Lef1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Lef1
cell proliferation
Mouse kidney carcinoma cell
Gene: Lef1 (lymphoid enhancer binding factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell proliferation, BMP signaling pathway, T cell receptor V(D)J recombination, T-helper 1 cell differentiation, Wnt signaling pathway, alpha-beta T cell differentiation, ana...
Does Knockout of Cinp in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Cinp
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Cinp (cyclin dependent kinase 2 interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, biological_process, cell division, ribosomal large subunit biogenesis, ribosome biogenesis; MF: molecular_function,...
Does Knockout of Wnt2b in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Wnt2b
cell proliferation
Embryonic Stem Cell Line
Gene: Wnt2b (wingless-type MMTV integration site family, member 2B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, animal organ morphogenesis, canonical Wnt signaling pathway, cell fate commitment, cell-cell signaling, cellular response to starvati...
Does Knockout of Fam131c in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Fam131c
cell proliferation
Mouse kidney carcinoma cell
Gene: Fam131c (family with sequence similarity 131, member C) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A2ADB2 Entrez ID: 277743
Does Knockout of Gtf2ird2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Gtf2ird2
cell proliferation
Mouse kidney carcinoma cell
Gene: Gtf2ird2 (GTF2I repeat domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of skeletal muscle adaptation, transition between fast and slow fiber; MF: DNA binding, protein binding; CC: nucleus Pathways: UniProt: Q99NI3 ...
Does Knockout of Klc4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Klc4
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Klc4 (kinesin light chain 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axo-dendritic transport, microtubule-based movement; CC: ciliary rootlet, cytoplasm, cytoskeleton, kinesin complex, microtubule, neuron projection Pathways: Adaptive Immune System,...
Does Knockout of Tmem259 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Tmem259
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Tmem259 (transmembrane protein 259) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of ERAD pathway, response to endoplasmic reticulum stress; CC: endoplasmic reticulum, endoplasmic reticulum membrane, membrane Pathways: UniPro...
Does Knockout of Sectm1a in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Sectm1a
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Sectm1a (secreted and transmembrane 1A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: immune response, interleukin-2-mediated signaling pathway, positive regulation of T cell cytokine production, signal transduction; MF: cytokine activity, receptor ligand activity...
Does Knockout of Adora2b in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Adora2b
cell proliferation
Colonic Cancer Cell Line
Gene: Adora2b (adenosine A2b receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled adenosine receptor signaling pathway, G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, negative...
Does Knockout of Pid1 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Pid1
response to virus
Neuroblastoma Cell Line
Gene: Pid1 (phosphotyrosine interaction domain containing 1) Type: protein-coding Summary: Involved in several processes, including cellular response to cytokine stimulus; negative regulation of D-glucose import; and positive regulation of ATP biosynthetic process. Located in cytoplasm. Is expressed in ...
Does Knockout of Eif4a3 in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Eif4a3
cell cycle progression
breast epithelium
Gene: Eif4a3 (eukaryotic translation initiation factor 4A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, embryonic cranial skeleton morphogenesis, mRNA export from nucleus, mRNA processing, mRNA splicing, via spliceosome, mRNA transport, negative regulati...
Does Knockout of Zfp790 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Zfp790
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Zfp790 (zinc finger protein 790) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Nop14 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Nop14
protein/peptide accumulation
Embryonic Cell Line
Gene: Nop14 (NOP14 nucleolar protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of SSU-rRNA, rRNA processing, ribosomal small subunit biogenesis, ribosome biogenesis; MF: enzyme binding, snoRNA binding; CC: Noc4p-Nop14p complex, nucleolus, nucleoplasm, nu...
Does Knockout of Tpm4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Tpm4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tpm4 (tropomyosin 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament organization, muscle contraction, platelet formation; MF: actin binding, actin filament binding, identical protein binding, metal ion binding, protein heterodimerization activity, pr...
Does Knockout of Dguok in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Dguok
cell proliferation
Colonic Cancer Cell Line
Gene: Dguok (deoxyguanosine kinase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: dAMP salvage, dGMP salvage, dGTP metabolic process, dIMP salvage, mitochondrial ATP synthesis coupled electron transport, negative regulation of neuron projection development, nucleobase-c...
Does Knockout of Cerkl in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Cerkl
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Cerkl (ceramide kinase-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of apoptotic process, sphingolipid biosynthetic process, sphingolipid metabolic process; MF: kinase activity, lipid kinase activity, sphingolipid binding; CC: Golgi appa...
Does Knockout of Neil3 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Neil3
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Neil3 (nei like 3 (E. coli)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, base-excision repair, interstrand cross-link repair, single strand break repair; MF: DNA N-glycosylase activity, DNA binding, DNA-(apurinic or apyrimidinic ...
Does Knockout of Ostm1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Ostm1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ostm1 (osteopetrosis associated transmembrane protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: osteoclast differentiation, transepithelial chloride transport; CC: chloride channel complex, cytosol, lysosomal membrane, lysosome, membrane Pathways: ...
Does Knockout of Kcnrg in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Kcnrg
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Kcnrg (potassium channel regulator) Type: protein-coding Summary: Predicted to enable identical protein binding activity. Predicted to be involved in negative regulation of delayed rectifier potassium channel activity. Predicted to be active in endoplasmic reticulum. Orthologous to human KCNRG (po...
Does Knockout of Arpp19 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Arpp19
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Arpp19 (cAMP-regulated phosphoprotein 19) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G2/M transition of mitotic cell cycle, cell division, mitotic cell cycle, positive regulation of gluconeogenesis; MF: phosphatase inhibitor activity, potassium channel regulato...
Does Knockout of Peli3 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Peli3
phagocytosis
macrophage
Gene: Peli3 (pellino 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to Gram-negative bacterium, immune system process, innate immune response, negative regulation of Toll signaling pathway, negative regulation of extrinsic apoptotic signaling pathway,...
Does Knockout of Ccdc177 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Ccdc177
cell proliferation
Mouse kidney carcinoma cell
Gene: Ccdc177 (coiled-coil domain containing 177) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q3UHB8 Entrez ID: 380768
Does Knockout of Twf2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Twf2
cell proliferation
Mouse kidney carcinoma cell
Gene: Twf2 (twinfilin actin binding protein 2) Type: protein-coding Summary: Enables actin monomer binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in barbed-end actin filament capping. Located in several cellular components, including lamellipodium; myofibril; and s...
Does Knockout of Kank3 in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Kank3
cell proliferation
Melanoma Cell Line
Gene: Kank3 (KN motif and ankyrin repeat domains 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of actin filament polymerization, negative regulation of stress fiber assembly, podocyte cell migration, regulation of Rho protein signal transduction; ...
Does Knockout of Tmem33 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Tmem33
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Tmem33 (transmembrane protein 33) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endoplasmic reticulum tubular network organization, immune system process, innate immune response, membrane organization, positive regulation of IRE1-mediated unfolded protein response...
Does Knockout of Smim22 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Smim22
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Smim22 (small integral membrane protein 22) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid droplet formation, positive regulation of cell migration, regulation of actin cytoskeleton organization, regulation of cell cycle, regulation of cell population prolife...
Does Knockout of Aadac in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Aadac
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Aadac (arylacetamide deacetylase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid metabolic process, positive regulation of triglyceride catabolic process; MF: carboxylic ester hydrolase activity, catalytic activity, deacetylase activity, hydrolase activity, l...
Does Knockout of Zfp956 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,277
Knockout
Zfp956
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Zfp956 (zinc finger protein 956) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding, metal ion binding, zinc ion bi...
Does Knockout of Lrp8 in myoblast cell line causally result in protein/peptide distribution?
0
1,680
Knockout
Lrp8
protein/peptide distribution
myoblast cell line
Gene: Lrp8 (low density lipoprotein receptor-related protein 8, apolipoprotein e receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ammon gyrus development, cellular response to cholesterol, cellular response to growth factor stimulus, cerebral cortex development, ...
Does Knockout of Dhx58 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Dhx58
protein/peptide distribution
myoblast cell line
Gene: Dhx58 (DExH-box helicase 58) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antiviral innate immune response, cytoplasmic pattern recognition receptor signaling pathway, defense response to virus, immune system process, innate immune response, negative regulation o...
Does Knockout of Trim35 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Trim35
phagocytosis
macrophage
Gene: Trim35 (tripartite motif-containing 35) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, innate immune response, negative regulation of cell population proliferation, negative regulation of mitotic cell cycle, positive regulation of apoptotic proce...
Does Knockout of GM20481 in macrophage causally result in phagocytosis?
0
1,888
Knockout
GM20481
phagocytosis
macrophage
Gene: Gm20481 (predicted gene 20481) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Rin3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Rin3
cell proliferation
Mouse kidney carcinoma cell
Gene: Rin3 (Ras and Rab interactor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of mast cell chemotaxis, negative regulation of receptor internalization, regulation of vesicle size, signal transduction, vesicle-mediated transport; MF: GTPase acti...
Does Knockout of Fosb in Melanoma Cell Line causally result in cell proliferation?
0
1,838
Knockout
Fosb
cell proliferation
Melanoma Cell Line
Gene: Fosb (FBJ osteosarcoma oncogene B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: behavioral response to cocaine, cellular response to calcium ion, cellular response to hormone stimulus, female pregnancy, positive regulation of transcription by RNA polymerase II, r...
Does Knockout of Snx22 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Snx22
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Snx22 (sorting nexin 22) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, protein transport; MF: lipid binding, molecular_function, phosphatidylinositol binding, phosphatidylinositol phosphate binding; CC: cellular_component, cytoplasmic vesicle, ...
Does Knockout of Tspo2 in Melanoma Cell Line causally result in cell proliferation?
0
1,838
Knockout
Tspo2
cell proliferation
Melanoma Cell Line
Gene: Tspo2 (translocator protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 5-aminolevulinic acid import across plasma membrane, enucleate erythrocyte differentiation, import across plasma membrane, intracellular cholesterol transport, lipid droplet organization;...
Does Knockout of Usp32 in myoblast cell line causally result in protein/peptide distribution?
0
1,685
Knockout
Usp32
protein/peptide distribution
myoblast cell line
Gene: Usp32 (ubiquitin specific peptidase 32) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of TORC1 signaling, protein deubiquitination, proteolysis; MF: calcium ion binding, cysteine-type deubiquitinase activity, cysteine-type peptidase activity, h...
Does Knockout of Atp8b2 in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Atp8b2
response to bacteria
renal medulla cell line
Gene: Atp8b2 (ATPase, class I, type 8B, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, lipid transport, phospholipid translocation, phospholipid transport; MF: ATP binding, ATP hydrolysis activity, ATPase-coupled intramembrane lipid transpor...
Does Knockout of Nuak2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Nuak2
cell proliferation
Mouse kidney carcinoma cell
Gene: Nuak2 (NUAK family, SNF1-like kinase, 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, apoptotic process, cellular response to glucose starvation, negative regulation of apoptotic process, protein localization to nucleus, protein p...
Does Knockout of Casp7 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Casp7
protein/peptide distribution
myoblast cell line
Gene: Casp7 (caspase 7) Type: protein-coding Summary: Enables aspartic-type endopeptidase activity and cysteine-type endopeptidase activity. Involved in lymphocyte apoptotic process and protein maturation. Acts upstream of or within several processes, including ceramide biosynthetic process; fibroblast ...
Does Knockout of Scnn1b in myoblast cell line causally result in protein/peptide distribution?
0
1,685
Knockout
Scnn1b
protein/peptide distribution
myoblast cell line
Gene: Scnn1b (sodium channel, nonvoltage-gated 1 beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: aldosterone metabolic process, artery smooth muscle contraction, blood circulation, cellular response to acidic pH, cellular response to aldosterone, cellular response t...
Does Knockout of Arl10 in Melanoma Cell Line causally result in protein/peptide accumulation?
1
1,839
Knockout
Arl10
protein/peptide accumulation
Melanoma Cell Line
Gene: Arl10 (ADP-ribosylation factor-like 10) Type: protein-coding Summary: No summary available. Gene Ontology: MF: GTP binding, GTPase activity, molecular_function, nucleotide binding Pathways: UniProt: Q9QXJ4 Entrez ID: 56795
Does Knockout of Naa15 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Naa15
cell proliferation
Mouse kidney carcinoma cell
Gene: Naa15 (N(alpha)-acetyltransferase 15, NatA auxiliary subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, cell differentiation, negative regulation of apoptotic process, positive regulation of DNA-templated transcription, protein stabilization; MF:...
Does Knockout of Arhgef39 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Arhgef39
cell viability
Immortal mouse chromaffin cells
Gene: Arhgef39 (Rho guanine nucleotide exchange factor 39) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of cell migration; CC: membrane, plasma membrane Pathways: Cell death signalling via NRAGE, NRIF and NADE, Death Receptor Signaling, G a...
Does Knockout of Cd209g in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,261
Knockout
Cd209g
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cd209g (CD209g antigen) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carbohydrate binding, pattern recognition receptor activity Pathways: C-type lectin receptor signaling pathway - Mus musculus (mouse), Measles - Mus musculus (mouse), Phagosome - Mus mu...
Does Knockout of Scrn3 in Non-Small Cell Lung Cancer Cell Line causally result in tumorigenicity?
0
2,189
Knockout
Scrn3
tumorigenicity
Non-Small Cell Lung Cancer Cell Line
Gene: Scrn3 (secernin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: detection of temperature stimulus involved in sensory perception of pain, proteolysis; MF: cysteine-type exopeptidase activity, dipeptidase activity, molecular_function Pathways: U...
Does Knockout of Uchl5 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,178
Knockout
Uchl5
tumorigenicity
Colonic Cancer Cell Line
Gene: Uchl5 (ubiquitin carboxyl-terminal esterase L5) Type: protein-coding Summary: Predicted to enable cysteine-type deubiquitinase activity; endopeptidase inhibitor activity; and proteasome binding activity. Involved in several processes, including brain development; positive regulation of DNA metabol...
Does Knockout of Gm20904 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Gm20904
phagocytosis
macrophage
Gene: Gm20904 (predicted gene, 20904) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Ociad2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Ociad2
cell proliferation
Mouse kidney carcinoma cell
Gene: Ociad2 (OCIA domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell migration, mitochondrial respiratory chain complex III assembly, response to bacterium; CC: endosome, membrane, mitochondrial inner membrane, mitochondrion Pathways: ...
Does Knockout of Lsm10 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
84
Knockout
Lsm10
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Lsm10 (U7 snRNP-specific Sm-like protein LSM10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA 3'-end processing by stem-loop binding and cleavage, mRNA processing, positive regulation of G1/S transition of mitotic cell cycle; MF: RNA binding, U7...