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Does Knockout of Rimklb in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Rimklb
cell proliferation
Melanoma Cell Line
Gene: Rimklb (ribosomal modification protein rimK-like family member B) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, N-acetyl-L-aspartate-L-glutamate ligase activity, citrate-L-glutamate ligase activity, ligase activity, metal ion binding, nucleotide bindi...
Does Knockout of Mpv17l in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Mpv17l
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mpv17l (Mpv17 transgene, kidney disease mutant-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of hydrogen peroxide biosynthetic process, negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling p...
Does Knockout of Mrpl12 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Mrpl12
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Mrpl12 (mitochondrial ribosomal protein L12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial transcription, mitochondrial translation, positive regulation of DNA-templated transcription, translation; MF: mRNA binding, structural constituent of ribosome...
Does Knockout of Dsc3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Dsc3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Dsc3 (desmocollin 3) Type: protein-coding Summary: This gene encodes a member of the cadherin family of proteins that mediates adhesion in desmosomes. Together with desmogleins, the encoded protein forms the transmembrane core of desmosomes, a multiprotein complex involved in cell adhesion, organi...
Does Knockout of Nucb2 in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
0
2,474
Knockout
Nucb2
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Nucb2 (nucleobindin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: insulin metabolic process, intracellular calcium ion homeostasis, negative regulation of appetite, negative regulation of cAMP/PKA signal transduction, negative regulation of fat cell differentia...
Does Knockout of Stap1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Stap1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Stap1 (signal transducing adaptor family member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor protein tyrosine kinase signaling pathway, cellular response to lipopolysaccharide, myeloid cell differentiation, negative regulation of macropha...
Does Knockout of Gdf10 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,308
Knockout
Gdf10
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Gdf10 (growth differentiation factor 10) Type: protein-coding Summary: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcri...
Does Knockout of Il34 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Il34
phagocytosis
macrophage
Gene: Il34 (interleukin 34) Type: protein-coding Summary: Predicted to enable identical protein binding activity and macrophage colony-stimulating factor receptor binding activity. Involved in microglial cell proliferation; positive regulation of gene expression; and positive regulation of oligodendrocy...
Does Knockout of Tbc1d23 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Tbc1d23
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Tbc1d23 (TBC1 domain family, member 23) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, brain development, embryonic brain development, nervous system development, neuron projection development, positive regulation of interleukin-6 producti...
Does Knockout of Gm10419 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Gm10419
phagocytosis
macrophage
Gene: Gm10419 (predicted gene 10419) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Uqcc1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,481
Knockout
Uqcc1
protein/peptide accumulation
Regulatory T cell
Gene: Uqcc1 (ubiquinol-cytochrome c reductase complex assembly factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial respiratory chain complex III assembly; CC: cytoplasmic vesicle, membrane, mitochondrial inner membrane, mitochondrion Pathways:...
Does Knockout of Sulf1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Sulf1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sulf1 (sulfatase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, bone development, cartilage condensation, cartilage development, cell adhesion, chondrocyte development, embryonic skeletal system development, esophagus smooth muscle contraction...
Does Knockout of Cga in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Cga
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cga (glycoprotein hormones, alpha subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, cellular response to hormone stimulus, developmental growth, follicle-stimulating hormone secretion, gonad development, luteinizi...
Does Knockout of Nbr1 in myoblast cell line causally result in protein/peptide distribution?
1
1,682
Knockout
Nbr1
protein/peptide distribution
myoblast cell line
Gene: Nbr1 (NBR1, autophagy cargo receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: macroautophagy, negative regulation of osteoblast differentiation, regulation of bone mineralization, regulation of stress-activated MAPK cascade; MF: metal ion binding, mitogen-ac...
Does Knockout of Rhobtb3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,259
Knockout
Rhobtb3
cell proliferation
Mouse kidney carcinoma cell
Gene: Rhobtb3 (Rho-related BTB domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: male gonad development, proteasome-mediated ubiquitin-dependent protein catabolic process, regulation of proteolysis, retrograde transport, endosome to Golgi; MF: ATP bindi...
Does Knockout of 1700001O22Rik in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
1700001O22Rik
cell proliferation
Mammary Gland Tumor Cell Line
Gene: 1700001O22Rik (RIKEN cDNA 1700001O22 gene) Type: protein-coding Summary: Orthologous to human C9orf50 (chromosome 9 open reading frame 50). [provided by Alliance of Genome Resources, Apr 2025] Gene Ontology: CC: cellular_component, cytoplasm Pathways: UniProt: A2APZ1 ...
Does Knockout of Cyp2b9 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Cyp2b9
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cyp2b9 (cytochrome P450, family 2, subfamily b, polypeptide 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: epoxygenase P450 pathway, ketone metabolic process, response to stilbenoid, steroid metabolic process, xenobiotic catabolic process, xenobiotic metabolic p...
Does Knockout of Gm3558 in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Gm3558
response to bacteria
renal medulla cell line
Gene: Gm3558 (predicted gene 3558) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q5FWC9 Entrez ID: 100041874
Does Knockout of Gkn1 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Gkn1
response to virus
Microglial Cell Line
Gene: Gkn1 (gastrokine 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of cell division, positive regulation of cell population proliferation, regulation of cell population proliferation, signal transduction; CC: Golgi apparatus, cytoplasm, endomemb...
Does Knockout of Ruvbl1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Ruvbl1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ruvbl1 (RuvB-like AAA ATPase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, box C/D snoRNP assembly, cell division, chromatin organization, chromatin remodeling, positive regulation of DNA repair, positive regu...
Does Knockout of Ces2d-ps in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Ces2d-ps
cell proliferation
Mouse kidney carcinoma cell
Gene: Ces2d-ps (carboxylesterase 2D, pseudogene) Type: pseudo Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 667754
Does Knockout of Acot13 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Acot13
cell proliferation
Mouse kidney carcinoma cell
Gene: Acot13 (acyl-CoA thioesterase 13) Type: protein-coding Summary: Enables fatty acyl-CoA hydrolase activity. Involved in negative regulation of cold-induced thermogenesis. Located in mitochondrial matrix. Is expressed in chondrocranium; hindgut; and midgut. Orthologous to human ACOT13 (acyl-CoA thio...
Does Knockout of Irak3 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Irak3
response to virus
Neuroblastoma Cell Line
Gene: Irak3 (interleukin-1 receptor-associated kinase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Toll signaling pathway, apoptotic process, cytokine-mediated signaling pathway, interleukin-1-mediated signaling pathway, intracellular signal transduction, lipopolysa...
Does Knockout of Adtrp in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,277
Knockout
Adtrp
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Adtrp (androgen dependent TFPI regulating protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell migration involved in sprouting angiogenesis, cellular response to oxidised low-density lipoprotein particle stimulus, cellular response to steroid hormone stimul...
Does Knockout of Dpf3 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Dpf3
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Dpf3 (double PHD fingers 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, muscle cell differentiation, muscle organ development, nervous system development, positive regulation of cell differentiation, positive regulat...
Does Knockout of Mrpl55 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
1,664
Knockout
Mrpl55
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Mrpl55 (mitochondrial ribosomal protein L55) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: structural constituent of ribosome; CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrion, ribon...
Does Knockout of Etv6 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Etv6
protein/peptide accumulation
Embryonic Cell Line
Gene: Etv6 (ets variant 6) Type: protein-coding Summary: This gene encodes a transcriptional repressor belonging to the ETS family of proteins. Knockout of this gene in mice results in embryonic lethality due to defective angiogenesis. In humans, this gene is often involved in chromosome rearrangements ...
Does Knockout of Prg2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Prg2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Prg2 (proteoglycan 2, bone marrow) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to bacterium, defense response to nematode, immune response, immune system process, negative regulation of interleukin-10 production, negative regulation of macrophag...
Does Knockout of Copz1 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,178
Knockout
Copz1
tumorigenicity
Colonic Cancer Cell Line
Gene: Copz1 (coatomer protein complex, subunit zeta 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intra-Golgi vesicle-mediated transport, intracellular protein transport, protein transport, retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum, vesicl...
Does Knockout of Slc41a1 in myoblast cell line causally result in protein/peptide distribution?
1
1,685
Knockout
Slc41a1
protein/peptide distribution
myoblast cell line
Gene: Slc41a1 (solute carrier family 41, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to magnesium ion, intracellular magnesium ion homeostasis, magnesium ion transmembrane transport, magnesium ion transport, metal ion transport, monoatomic ...
Does Knockout of Dlg3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Dlg3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Dlg3 (discs large MAGUK scaffold protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell-cell adhesion, chemical synaptic transmission, establishment of planar polarity, establishment or maintenance of epithelial cell apical/basal polarity, nervous system de...
Does Knockout of A3galt2 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
A3galt2
response to virus
Microglial Cell Line
Gene: A3galt2 (alpha 1,3-galactosyltransferase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate metabolic process, cellular response to manganese ion, glycosphingolipid biosynthetic process, lipid metabolic process; MF: N-acetyllactosaminide 3-alpha-galacto...
Does Knockout of Fbxo8 in myoblast cell line causally result in protein/peptide distribution?
0
1,683
Knockout
Fbxo8
protein/peptide distribution
myoblast cell line
Gene: Fbxo8 (F-box protein 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of ARF protein signal transduction, ubiquitin-dependent protein catabolic process; MF: guanyl-nucleotide exchange factor activity Pathways: UniProt: Q9QZN3 ...
Does Knockout of Rnf144a in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Rnf144a
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Rnf144a (ring finger protein 144A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic pattern recognition receptor signaling pathway, pattern recognition receptor signaling pathway, protein K6-linked ubiquitination, protein ubiquitination, ubiquitin-depende...
Does Knockout of Med1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Med1
cell proliferation
Mouse kidney carcinoma cell
Gene: Med1 (mediator complex subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, androgen biosynthetic process, angiogenesis, animal organ morphogenesis, animal organ regeneration, brain development, camera-type eye...
Does Knockout of Scaper in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Scaper
cell proliferation
Mouse kidney carcinoma cell
Gene: Scaper (S phase cyclin A-associated protein in the ER) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antral ovarian follicle growth, ovarian follicle development, retina development in camera-type eye, seminiferous tubule development, spermatogenesis; MF: molecula...
Does Knockout of Obsl1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,481
Knockout
Obsl1
protein/peptide accumulation
Regulatory T cell
Gene: Obsl1 (obscurin-like 1) Type: protein-coding Summary: Predicted to be involved in several processes, including positive regulation of dendrite morphogenesis; protein localization to Golgi apparatus; and regulation of mitotic nuclear division. Predicted to be located in Golgi apparatus; centrosome;...
Does Knockout of Syt15 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Syt15
protein/peptide accumulation
Embryonic Cell Line
Gene: Syt15 (synaptotagmin XV) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of calcium ion-dependent exocytosis, vesicle-mediated transport; MF: SNARE binding, calcium ion sensor activity, calcium-dependent phospholipid binding; CC: exocytic vesicle, membran...
Does Knockout of Rps6ka5 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,663
Knockout
Rps6ka5
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Rps6ka5 (ribosomal protein S6 kinase, polypeptide 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: TORC1 signaling, chromatin remodeling, inflammatory response, interleukin-1-mediated signaling pathway, intracellular signal transduction, negative regulation of DNA...
Does Knockout of Polk in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Polk
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Polk (polymerase (DNA directed), kappa) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA biosynthetic process, DNA damage response, DNA repair, DNA replication, cellular response to UV, error-prone translesion synthesis, nucleotide-excision repair, DNA gap fillin...
Does Knockout of Mill1 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Mill1
cell proliferation
Melanoma Cell Line
Gene: Mill1 (MHC I like leukocyte 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: natural killer cell lectin-like receptor binding, protein binding, receptor ligand activity; CC: cell surface, external side of plasma membrane, extracellular space, membrane, plasma memb...
Does Knockout of Camk1g in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,179
Knockout
Camk1g
cell proliferation
Colonic Cancer Cell Line
Gene: Camk1g (calcium/calmodulin-dependent protein kinase I gamma) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, calcium/calmodulin-dependent protein kinase activity, calmodulin binding, catalytic activity, kinase activity, nucleotide binding, protein kinas...
Does Knockout of Fjx1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Fjx1
cell proliferation
Mouse kidney carcinoma cell
Gene: Fjx1 (four jointed box 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell-cell signaling, retina layer formation; CC: extracellular region, extracellular space Pathways: UniProt: Q8BQB4 Entrez ID: 14221
Does Knockout of Cadm2 in Microglial Cell Line causally result in protein/peptide distribution?
1
1,585
Knockout
Cadm2
protein/peptide distribution
Microglial Cell Line
Gene: Cadm2 (cell adhesion molecule 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules, synaptic membrane adhesion; CC: GABA-ergic synapse, axon, cell projection, glutamatergic synapse, membran...
Does Knockout of Lasp1 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Lasp1
protein/peptide distribution
myoblast cell line
Gene: Lasp1 (LIM and SH3 protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport; MF: actin binding, actin filament binding, metal ion binding, monoatomic ion transmembrane transporter activity, protein b...
Does Knockout of Clec2h in pro-B-lymphocyte causally result in response to chemicals?
0
1,720
Knockout
Clec2h
response to chemicals
pro-B-lymphocyte
Gene: Clec2h (C-type lectin domain family 2, member h) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carbohydrate binding, natural killer cell lectin-like receptor binding, transmembrane signaling receptor activity; CC: cell surface, endoplasmic reticulum, external side...
Does Knockout of Syt13 in Microglial Cell Line causally result in regulation of lipid localization?
0
1,678
Knockout
Syt13
regulation of lipid localization
Microglial Cell Line
Gene: Syt13 (synaptotagmin XIII) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium-dependent activation of synaptic vesicle fusion, regulation of calcium ion-dependent exocytosis, regulation of synaptic vesicle exocytosis, vesicle-mediated transport; MF: SNARE bindi...
Does Knockout of Zfp472 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Zfp472
protein/peptide distribution
myoblast cell line
Gene: Zfp472 (zinc finger protein 472) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Ptpn23 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,177
Knockout
Ptpn23
tumorigenicity
Colonic Cancer Cell Line
Gene: Ptpn23 (protein tyrosine phosphatase, non-receptor type 23) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, cilium assembly, early endosome to late endosome transport, endocytic recycling, negative regulation of epithelial cell migratio...
Does Knockout of Tubal3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Tubal3
cell proliferation
Mouse kidney carcinoma cell
Gene: Tubal3 (tubulin, alpha-like 3) Type: protein-coding Summary: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be active in cytoplasm and microtu...
Does Knockout of Rnpep in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,175
Knockout
Rnpep
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Rnpep (arginyl aminopeptidase (aminopeptidase B)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of blood pressure, protein processing, proteolysis; MF: aminopeptidase activity, cobalt ion binding, copper ion binding, hydrolase activity, metal i...
Does Knockout of Scin in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Scin
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Scin (scinderin) Type: protein-coding Summary: Predicted to enable actin filament binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Predicted to be involved in several processes, including actin polymerization or depolymerization; positive regulation of megakaryocyte dif...
Does Knockout of Tubg1 in Melanoma Cell Line causally result in cell proliferation?
1
1,270
Knockout
Tubg1
cell proliferation
Melanoma Cell Line
Gene: Tubg1 (tubulin, gamma 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic microtubule organization, meiotic spindle organization, microtubule nucleation, microtubule-based process, mitotic cell cycle, mitotic sister chromatid segregation, mitotic spindle ...
Does Knockout of Gprc5c in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Gprc5c
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Gprc5c (G protein-coupled receptor, family C, group 5, member C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction, visual perception; MF: G protein-coupled receptor activity, protein kinase activator a...
Does Knockout of Pdgfb in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Pdgfb
protein/peptide accumulation
Embryonic Cell Line
Gene: Pdgfb (platelet derived growth factor, B polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, angiogenesis, blood vessel development, blood vessel morphogenesis, branching involved in salivary gland morphogenesis, cardiac vas...
Does Knockout of Colec12 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Colec12
protein/peptide accumulation
Microglial Cell Line
Gene: Colec12 (collectin sub-family member 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to bacterium, immune response, phagocytosis, recognition, plasma membrane raft organization; MF: carbohydrate binding, low-density lipoprotein particle binding,...
Does Knockout of Kif5a in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,180
Knockout
Kif5a
tumorigenicity
Colonic Cancer Cell Line
Gene: Kif5a (kinesin family member 5A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterograde axonal protein transport, anterograde dendritic transport of neurotransmitter receptor complex, axon guidance, microtubule-based movement, retrograde neuronal dense core ves...
Does Knockout of Nono in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,259
Knockout
Nono
cell proliferation
Mouse kidney carcinoma cell
Gene: Nono (non-POU-domain-containing, octamer binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, RNA splicing, activation of innate immune response, cellular response to angiotensin, cellular response to h...
Does Knockout of Fv1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Fv1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Fv1 (Friend virus susceptibility 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to virus, response to virus; CC: Golgi apparatus Pathways: UniProt: P70213 Entrez ID: 14349
Does Knockout of Phax in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Phax
response to bacteria
renal medulla cell line
Gene: Phax (phosphorylated adaptor for RNA export) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA stabilization, protein transport, snRNA export from nucleus; MF: RNA binding, mRNA cap binding complex binding, toxic substance binding; CC: Cajal body, cytoplasm, neuro...
Does Knockout of Vmn1r218 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Vmn1r218
protein/peptide distribution
myoblast cell line
Gene: Vmn1r218 (vomeronasal 1 receptor 218) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromon...
Does Knockout of Serhl in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Serhl
cell proliferation
Mouse kidney carcinoma cell
Gene: Serhl (serine hydrolase-like) Type: protein-coding Summary: No summary available. Gene Ontology: MF: hydrolase activity; CC: cytoplasm, cytoplasmic vesicle, mitochondrion, perinuclear region of cytoplasm, peroxisome Pathways: UniProt: Q9EPB5 Entrez ID: 68607
Does Knockout of Sppl3 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Sppl3
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Sppl3 (signal peptide peptidase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell receptor signaling pathway, membrane protein ectodomain proteolysis, membrane protein proteolysis, positive regulation of calcineurin-NFAT signaling cascade, positive regulatio...
Does Knockout of Trpc5 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,179
Knockout
Trpc5
cell proliferation
Colonic Cancer Cell Line
Gene: Trpc5 (transient receptor potential cation channel, subfamily C, member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion transmembrane transport, calcium ion transport, monoatomic ion transmembrane transport, monoatomic ion transport, negative regulati...
Does Knockout of Cdhr3 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Cdhr3
response to chemicals
Pancreatic Cancer Cell Line
Gene: Cdhr3 (cadherin-related family member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding; CC: membrane, plasma membrane P...
Does Knockout of Plekhm3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Plekhm3
cell proliferation
Mouse kidney carcinoma cell
Gene: Plekhm3 (pleckstrin homology domain containing, family M, member 3) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, protein binding, zinc ion binding; CC: Golgi apparatus, cytoplasm, membrane, plasma membrane Pathways: UniProt: ...
Does Knockout of Taldo1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Taldo1
cell proliferation
Mouse kidney carcinoma cell
Gene: Taldo1 (transaldolase 1) Type: protein-coding Summary: This gene encodes a key enzyme of the nonoxidative pentose phosphate pathway that provides ribose-5-phosphate for nucleic acid synthesis and nicotinamide adenine dinucleotide phosphate (NADPH) for lipid biosynthesis. The encoded protein is imp...
Does Knockout of Erich1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,261
Knockout
Erich1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Erich1 (glutamate rich 1) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q3UGP3, E9PY43, A0A1B0GRP9 Entrez ID: 234086
Does Knockout of Dusp19 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Dusp19
cell proliferation
Embryonic Stem Cell Line
Gene: Dusp19 (dual specificity phosphatase 19) Type: protein-coding Summary: Enables several functions, including phosphoprotein phosphatase activity; protein kinase binding activity; and protein kinase regulator activity. Involved in negative regulation of JUN kinase activity; positive regulation of JN...
Does Knockout of Aldh5a1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,308
Knockout
Aldh5a1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Aldh5a1 (aldhehyde dehydrogenase family 5, subfamily A1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: central nervous system development, gamma-aminobutyric acid catabolic process, gamma-aminobutyric acid metabolic process, glutamate metabolic process, post-embry...
Does Knockout of Dnajc30 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Dnajc30
cell proliferation
Melanoma Cell Line
Gene: Dnajc30 (DnaJ heat shock protein family (Hsp40) member C30) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ATP biosynthetic process, brain development, regulation of mitochondrial ATP synthesis coupled proton transport; CC: membrane, mitochondrial inner membrane, m...
Does Knockout of Xrcc4 in Lymphoma Cell Line causally result in response to chemicals?
0
1,549
Knockout
Xrcc4
response to chemicals
Lymphoma Cell Line
Gene: Xrcc4 (X-ray repair complementing defective repair in Chinese hamster cells 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DN2 thymocyte differentiation, DNA damage response, DNA recombination, DNA repair, V(D)J recombination, base-excision repair, central nervo...
Does Knockout of Yy1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
1,664
Knockout
Yy1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Yy1 (YY1 transcription factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, DNA damage response, DNA recombination, DNA repair, RNA localization, anterior/posterior pattern specification, camera-type eye morphogenesis, cell differentiation...
Does Knockout of Gm8267 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Gm8267
protein/peptide accumulation
Microglial Cell Line
Gene: Gm8267 (predicted gene 8267) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: E9Q207, E9PW76 Entrez ID: 666744
Does Knockout of Pde7a in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Pde7a
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Pde7a (phosphodiesterase 7A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cAMP catabolic process, negative regulation of cAMP/PKA signal transduction, signal transduction; MF: 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cyclic-GMP phosphodiesterase activit...
Does Knockout of Slc38a8 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Slc38a8
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Slc38a8 (solute carrier family 38, member 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-alpha-amino acid transmembrane transport, amino acid transmembrane transport, amino acid transport, aspartate metabolic process, neuron projection development, optic nerve...
Does Knockout of Dkk1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Dkk1
autophagy
Embryonic Fibroblast Cell Line
Gene: Dkk1 (dickkopf WNT signaling pathway inhibitor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, Wnt signaling pathway involved in somitogenesis, cell morphogenesis, embryonic limb morphogenesis, endoderm development, endoderm formation, endo...
Does Knockout of Csnk1d in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Csnk1d
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Csnk1d (casein kinase 1, delta) Type: protein-coding Summary: This gene encodes a member of the casein kinase I (CKI) family of serine/threonine protein kinases. A highly similar human protein regulates an array of cellular processes by influencing the Wnt and hedgehog signaling pathways. The enco...
Does Knockout of Slc25a4 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Slc25a4
cell proliferation
Colonic Cancer Cell Line
Gene: Slc25a4 (solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ADP transport, adaptive thermogenesis, apoptotic mitochondrial changes, mitochondrial ADP transmembrane transport, m...
Does Knockout of Hsf3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Hsf3
cell proliferation
Mouse kidney carcinoma cell
Gene: Hsf3 (heat shock transcription factor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to heat, positive regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription; MF: DNA binding, DNA-binding transcription facto...
Does Knockout of Sin3a in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Sin3a
cell proliferation
Regulatory T cell
Gene: Sin3a (transcriptional regulator, SIN3A (yeast)) Type: protein-coding Summary: Enables several functions, including RNA polymerase II-specific DNA-binding transcription factor binding activity; chromatin binding activity; and transcription corepressor activity. Involved in several processes, inclu...
Does Knockout of Paf1 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Paf1
cell cycle progression
breast epithelium
Gene: Paf1 (Paf1, RNA polymerase II complex component) Type: protein-coding Summary: Enables chromatin binding activity. Involved in several processes, including cellular response to lipopolysaccharide; endodermal cell fate commitment; and negative regulation of transcription by RNA polymerase II. Part ...
Does Knockout of Rock2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,307
Knockout
Rock2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Rock2 (Rho-associated coiled-coil containing protein kinase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rho protein signal transduction, actin cytoskeleton organization, actomyosin structure organization, blood vessel diameter maintenance, cellular response t...
Does Knockout of Rai14 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Rai14
cell cycle progression
breast epithelium
Gene: Rai14 (retinoic acid induced 14) Type: protein-coding Summary: Predicted to enable actin binding activity. Predicted to be involved in cell differentiation and spermatogenesis. Located in mitochondrion. Is expressed in several structures, including brain; genitourinary system; jaw; neural ectoderm...
Does Knockout of Kctd12b in myoblast cell line causally result in protein/peptide distribution?
0
1,680
Knockout
Kctd12b
protein/peptide distribution
myoblast cell line
Gene: Kctd12b (potassium channel tetramerisation domain containing 12b) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transmembrane transport, protein homooligomerization, regulation of G protein-coupled receptor signaling pathway, regulation of presynapt...
Does Knockout of Bcs1l in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,277
Knockout
Bcs1l
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Bcs1l (BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone) Type: protein-coding Summary: The protein encoded by this gene is a chaperone protein that is involved in the assembly of complex III (CIII), one of the five protein complexes of the mitochondrial respiratory chain, and is ne...
Does Knockout of Itga2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Itga2
cell proliferation
Mouse kidney carcinoma cell
Gene: Itga2 (integrin alpha 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell adhesion mediated by integrin, cell-cell adhesion, cell-matrix adhesion, cell-substrate adhesion, cellular response to estradiol stimulus, cellular response to mechanical st...
Does Knockout of Cplx4 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Cplx4
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Cplx4 (complexin 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: exocytosis, modulation of chemical synaptic transmission, neurotransmitter transport, regulation of neurotransmitter secretion, regulation of synaptic vesicle fusion to presynaptic active zone membr...
Does Knockout of Ankrd23 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Ankrd23
protein/peptide accumulation
Embryonic Cell Line
Gene: Ankrd23 (ankyrin repeat domain 23) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid metabolic process, positive regulation of transcription by RNA polymerase II, regulation of sarcomere organization, response to mechanical stimulus, response to muscle stre...
Does Knockout of Cd79b in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Cd79b
cell cycle progression
breast epithelium
Gene: Cd79b (CD79B antigen) Type: protein-coding Summary: The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expre...
Does Knockout of Smim7 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Smim7
protein/peptide accumulation
Mouse cell
Gene: Smim7 (small integral membrane protein 7) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q5RKS2 Entrez ID: 66818
Does Knockout of Uqcc1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Uqcc1
cell proliferation
Embryonic Stem Cell Line
Gene: Uqcc1 (ubiquinol-cytochrome c reductase complex assembly factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial respiratory chain complex III assembly; CC: cytoplasmic vesicle, membrane, mitochondrial inner membrane, mitochondrion Pathways:...
Does Knockout of Tmem248 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,263
Knockout
Tmem248
cell proliferation
Colonic Cancer Cell Line
Gene: Tmem248 (transmembrane protein 248) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q3TBN1 Entrez ID: 71667
Does Knockout of Ankrd61 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,308
Knockout
Ankrd61
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ankrd61 (ankyrin repeat domain 61) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, molecular_function; CC: nucleoplasm Pathways: UniProt: Q9CQM6 Entrez ID: 66729
Does Knockout of Card9 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,398
Knockout
Card9
protein/peptide accumulation
Microglial Cell Line
Gene: Card9 (caspase recruitment domain family, member 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, antifungal innate immune response, apoptotic signaling pathway, defense response to Gram-positive bacterium, defense response to virus, host...
Does Knockout of Insc in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Insc
protein/peptide distribution
Microglial Cell Line
Gene: Insc (INSC spindle orientation adaptor protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apical protein localization, asymmetric cell division, cell differentiation, nervous system development, regulation of asymmetric cell division, regulation of protein sta...
Does Knockout of Nwd2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Nwd2
cell proliferation
Mouse kidney carcinoma cell
Gene: Nwd2 (NACHT and WD repeat domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, synapse Pathways: UniProt: Q6P5U7 Entrez ID: 319807
Does Knockout of Zranb3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Zranb3
cell proliferation
Mouse kidney carcinoma cell
Gene: Zranb3 (zinc finger, RAN-binding domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, replication fork processing, replication fork reversal, response to UV; MF: ATP binding, ATP-dependent DNA/DNA annealing activity, ...
Does Knockout of Gnal in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Gnal
response to chemicals
Pancreatic Cancer Cell Line
Gene: Gnal (guanine nucleotide binding protein, alpha stimulating, olfactory type) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenylate cyclase-ac...
Does Knockout of Pcdhb21 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Pcdhb21
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Pcdhb21 (protocadherin beta 21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding, molecular_function; CC: membrane, plasma membrane...