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Does Knockout of Lce3e in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Lce3e
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Lce3e (late cornified envelope 3E) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, epidermis development, keratinization Pathways: UniProt: F8VQJ0 Entrez ID: 69514
Does Knockout of Nars2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
1
1,265
Knockout
Nars2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nars2 (asparaginyl-tRNA synthetase 2 (mitochondrial)(putative)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: asparaginyl-tRNA aminoacylation, tRNA aminoacylation for protein translation, translation; MF: ATP binding, aminoacyl-tRNA ligase activity, asparagine-tRN...
Does Knockout of Il22ra2 in Embryonic Fibroblast Cell Line causally result in cell proliferation?
0
345
Knockout
Il22ra2
cell proliferation
Embryonic Fibroblast Cell Line
Gene: Il22ra2 (interleukin 22 receptor, alpha 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytokine-mediated signaling pathway, interleukin-22-mediated signaling pathway, negative regulation of inflammatory response; MF: cytokine receptor activity, interleukin-22 bi...
Does Knockout of Nuak1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Nuak1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Nuak1 (NUAK family, SNF1-like kinase, 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, cell adhesion, protein phosphorylation, regulation of cell adhesion, regulation of cellular senescence; MF: ATP binding, kinase activity, nucleotide binding...
Does Knockout of Bcl2l12 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,259
Knockout
Bcl2l12
cell proliferation
Mouse kidney carcinoma cell
Gene: Bcl2l12 (BCL2 like 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, negative regulation of apoptotic process, negative regulation of cellular senescence, negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by ...
Does Knockout of Plk5 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Plk5
protein/peptide accumulation
Regulatory T cell
Gene: Plk5 (polo like kinase 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, cell differentiation, cell division, cellular response to growth factor stimulus, defense response to tumor cell, mitotic spindle organization, negative regulation of cell...
Does Knockout of Lcn4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Lcn4
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Lcn4 (lipocalin 4) Type: protein-coding Summary: No summary available. Gene Ontology: MF: molecular_function, odorant binding, pheromone binding, small molecule binding; CC: extracellular region, extracellular space Pathways: UniProt: Q62472 Entrez ID: 16821
Does Knockout of Csnk2a1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Csnk2a1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Csnk2a1 (casein kinase 2, alpha 1 polypeptide) Type: protein-coding Summary: Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythms. The k...
Does Knockout of Tacr1 in Melanoma Cell Line causally result in cell proliferation?
0
2,185
Knockout
Tacr1
cell proliferation
Melanoma Cell Line
Gene: Tacr1 (tachykinin receptor 1) Type: protein-coding Summary: This gene encodes the receptor for the tachykinin, substance P, also referred to as neurokinin 1. This gene belongs to a gene family of tachykinin receptors which are characterized by interactions with G proteins and contain seven hydroph...
Does Knockout of Fkbp6 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Fkbp6
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Fkbp6 (FK506 binding protein 6) Type: protein-coding Summary: This gene is a member of the FK506-binding protein (Fkbp) family. The encoded protein plays a role in male-specific fertility and homologous pairing of chromosomes during meiosis. The protein may also be involved in LINE1 transposon sil...
Does Knockout of Mir763 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Mir763
response to virus
Neuroblastoma Cell Line
Gene: Mir763 (microRNA 763) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase I...
Does Knockout of Steap1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Steap1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Steap1 (six transmembrane epithelial antigen of the prostate 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: heme binding, metal ion binding; CC: endosome, endosome membrane, membrane, plasma membrane Pathways: Mineral absorption - Mus musculus (mouse) ...
Does Knockout of Hus1 in Lymphoma Cell Line causally result in response to chemicals?
0
1,531
Knockout
Hus1
response to chemicals
Lymphoma Cell Line
Gene: Hus1 (HUS1 checkpoint clamp component) Type: protein-coding Summary: This gene encodes a component of a cell cycle checkpoint complex that causes cell cycle arrest in response to bulky DNA lesions and DNA replication blockage. Together with the proteins Rad9 and Rad1, the encoded protein forms a h...
Does Knockout of Ptbp1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Ptbp1
cell proliferation
Mouse kidney carcinoma cell
Gene: Ptbp1 (polypyrimidine tract binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: IRES-dependent viral translational initiation, RNA splicing, gene expression, mRNA processing, negative regulation of RNA splicing, negative regulation of gene expression,...
Does Knockout of Cct8 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Cct8
response to virus
Embryonic Fibroblast Cell Line
Gene: Cct8 (chaperonin containing TCP1 subunit 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: binding of sperm to zona pellucida, positive regulation of telomere maintenance via telomerase, protein folding, protein stabilization; MF: ATP binding, ATP hydrolysis activi...
Does Knockout of Gpm6b in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Gpm6b
cell proliferation
Melanoma Cell Line
Gene: Gpm6b (glycoprotein m6b) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon development, central nervous system myelination, extracellular matrix assembly, negative regulation of protein localization to cell surface, negative regulation of serotonin uptake, ossifi...
Does Knockout of Hmgcl in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
0
1,521
Knockout
Hmgcl
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Hmgcl (3-hydroxy-3-methylglutaryl-Coenzyme A lyase) Type: protein-coding Summary: Predicted to enable several functions, including anion binding activity; hydroxymethylglutaryl-CoA lyase activity; and metal ion binding activity. Acts upstream of or within mitochondrion organization. Located in mit...
Does Knockout of Cdc42ep4 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Cdc42ep4
protein/peptide accumulation
Embryonic Cell Line
Gene: Cdc42ep4 (CDC42 effector protein 4) Type: protein-coding Summary: Predicted to enable small GTPase binding activity. Acts upstream of or within Rho protein signal transduction and cellular response to type II interferon. Located in phagocytic vesicle. Is expressed in several structures, including ...
Does Knockout of Cd200r1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Cd200r1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Cd200r1 (CD200 receptor 1) Type: protein-coding Summary: Enables signaling receptor activity. Predicted to be involved in several processes, including negative regulation of interleukin-6 production; negative regulation of mononuclear cell migration; and negative regulation of neuroinflammatory re...
Does Knockout of Gabrg1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Gabrg1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gabrg1 (gamma-aminobutyric acid type A receptor subunit gamma 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chemical synaptic transmission, chloride transmembrane transport, chloride transport, gamma-aminobutyric acid signaling pathway, inhibitory synapse assem...
Does Knockout of Zfp141 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Zfp141
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfp141 (zinc finger protein 141) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Zc3h12b in Melanoma Cell Line causally result in cell proliferation?
0
2,488
Knockout
Zc3h12b
cell proliferation
Melanoma Cell Line
Gene: Zc3h12b (zinc finger CCCH-type containing 12B) Type: protein-coding Summary: No summary available. Gene Ontology: MF: RNA endonuclease activity, endonuclease activity, hydrolase activity, mRNA binding, metal ion binding, nuclease activity, zinc ion binding; CC: cytoplasmic ribonucleoprote...
Does Knockout of Adcy9 in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Adcy9
cell cycle progression
breast epithelium
Gene: Adcy9 (adenylate cyclase 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenylate cyclase-activating adrenergic receptor signaling pathway, cAMP biosynthetic process, cyclic nucleotide bi...
Does Knockout of Slc7a1 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Slc7a1
cell proliferation
Melanoma Cell Line
Gene: Slc7a1 (solute carrier family 7 (cationic amino acid transporter, y+ system), member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-amino acid transport, L-arginine import across plasma membrane, L-arginine transmembrane transport, L-histidine import across pl...
Does Knockout of Zfp710 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Zfp710
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfp710 (zinc finger protein 710) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, metal ion binding, zinc ion binding Pathways: Gen...
Does Knockout of Ssrp1 in Lung Cancer Cell Line causally result in tumorigenicity?
0
1,781
Knockout
Ssrp1
tumorigenicity
Lung Cancer Cell Line
Gene: Ssrp1 (structure specific recognition protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, nucleosome assembly, nucleosome disassembly, regulation of chromatin organization; MF: DNA binding, chromatin binding, ...
Does Knockout of Cyb5d2 in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Cyb5d2
cell proliferation
Melanoma Cell Line
Gene: Cyb5d2 (cytochrome b5 domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nervous system development, positive regulation of neuron differentiation; CC: endomembrane system, extracellular region, membrane Pathways: UniProt: Q5SSH8...
Does Knockout of Pof1b in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,279
Knockout
Pof1b
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Pof1b (premature ovarian failure 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, actin filament organization, bicellular tight junction assembly, epithelial cell morphogenesis; MF: actin binding, actin filament binding; CC: actin...
Does Knockout of Casc3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Casc3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Casc3 (exon junction complex subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, intracellular mRNA localization, mRNA export from nucleus, mRNA processing, mRNA splicing, via spliceosome, mRNA transport, nuclear-transcribed mRNA catabolic process...
Does Knockout of Tgm2 in myoblast cell line causally result in protein/peptide distribution?
0
1,683
Knockout
Tgm2
protein/peptide distribution
myoblast cell line
Gene: Tgm2 (transglutaminase 2, C polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, apoptotic cell clearance, blood vessel remodeling, bone development, branching involved in salivary gland morphogenesis, cellular r...
Does Knockout of Disp1 in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Disp1
cell proliferation
Melanoma Cell Line
Gene: Disp1 (dispatched RND transporter family member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: determination of left/right symmetry, diaphragm development, dorsal/ventral pattern formation, embryonic pattern specification, patched ligand maturation, peptide tran...
Does Knockout of Acin1 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Acin1
response to virus
Embryonic Fibroblast Cell Line
Gene: Acin1 (apoptotic chromatin condensation inducer 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, apoptotic chromosome condensation, apoptotic process, erythrocyte differentiation, mRNA processing, negative regulation of mRNA splicing, via spliceosome...
Does Knockout of Bcl2l12 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Bcl2l12
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Bcl2l12 (BCL2 like 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, negative regulation of apoptotic process, negative regulation of cellular senescence, negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by ...
Does Knockout of Iqcm in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Iqcm
response to bacteria
renal medulla cell line
Gene: Iqcm (IQ motif containing M) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9DAN0, Q149I8 Entrez ID: 71831
Does Knockout of Kiss1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Kiss1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Kiss1 (KiSS-1 metastasis-suppressor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, decidualization, generation of ovulation cycle rhythm, negative regulation of cell population proliferation, phospholipase C-activating...
Does Knockout of Ip6k3 in Melanoma Cell Line causally result in cell proliferation?
0
1,838
Knockout
Ip6k3
cell proliferation
Melanoma Cell Line
Gene: Ip6k3 (inositol hexaphosphate kinase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: inositol phosphate biosynthetic process, locomotion, phosphatidylinositol metabolic process, phosphatidylinositol phosphate biosynthetic process; MF: ATP binding, inositol hexaki...
Does Knockout of Ing3 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Ing3
phagocytosis
macrophage
Gene: Ing3 (inhibitor of growth family, member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, positive regulation of DNA-templated transcription, positive regulation of double-strand break repair via homologous recombinati...
Does Knockout of Zfp112 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,308
Knockout
Zfp112
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Zfp112 (zinc finger protein 112) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding tran...
Does Knockout of Acad8 in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
0
2,474
Knockout
Acad8
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Acad8 (acyl-Coenzyme A dehydrogenase family, member 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-valine catabolic process, branched-chain amino acid catabolic process, fatty acid beta-oxidation, lipid metabolic process; MF: acyl-CoA dehydrogenase activity, f...
Does Knockout of Svop in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Svop
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Svop (SV2 related protein) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasmic vesicle, membrane, synapse, synaptic vesicle, synaptic vesicle membrane Pathways: UniProt: Q8BFT9 Entrez ID: 68666
Does Knockout of Zkscan16 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Zkscan16
phagocytosis
macrophage
Gene: Zkscan16 (zinc finger with KRAB and SCAN domains 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymera...
Does Knockout of Ccl12 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Ccl12
cell proliferation
Colonic Cancer Cell Line
Gene: Ccl12 (C-C motif chemokine ligand 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, antimicrobial humoral immune response mediated by antimicrobial peptide, chemokine-mediated signaling pathway, chemotaxis, eosinophil chemotaxis, immune response, inf...
Does Knockout of Mir6916 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Mir6916
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Mir6916 (microRNA 6916) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Ndst3 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Ndst3
response to virus
Embryonic Fibroblast Cell Line
Gene: Ndst3 (N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3) Type: protein-coding Summary: Enables N-acetylglucosamine deacetylase activity and heparan sulfate N-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi membrane...
Does Knockout of Zyg11a in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Zyg11a
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Zyg11a (zyg-11 family member A, cell cycle regulator) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A0A1Y7VNL1, A0A217FL76, F8WHU3 Entrez ID: 230590
Does Knockout of Slc39a14 in myoblast cell line causally result in protein/peptide distribution?
0
1,683
Knockout
Slc39a14
protein/peptide distribution
myoblast cell line
Gene: Slc39a14 (solute carrier family 39 (zinc transporter), member 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bicarbonate transport, cadmium ion transmembrane transport, cellular response to glucose stimulus, cellular response to insulin stimulus, chondrocyte di...
Does Knockout of Xkr7 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Xkr7
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Xkr7 (X-linked Kx blood group related 7) Type: protein-coding Summary: Predicted to be involved in apoptotic process involved in development; engulfment of apoptotic cell; and phosphatidylserine exposure on apoptotic cell surface. Is active in plasma membrane. Orthologous to human XKR7 (XK related...
Does Knockout of Sycp3 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Sycp3
response to virus
Embryonic Fibroblast Cell Line
Gene: Sycp3 (synaptonemal complex protein 3) Type: protein-coding Summary: Predicted to enable DNA binding activity. Involved in female meiosis sister chromatid cohesion; meiotic chromosome segregation; and spermatogenesis. Acts upstream of or within several processes, including cellular response to leu...
Does Knockout of Ptov1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Ptov1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ptov1 (prostate tumor over expressed gene 1) Type: protein-coding Summary: Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of transcription regulator complex. Is expressed in several structures, inc...
Does Knockout of Nipsnap2 in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Nipsnap2
cell proliferation
Regulatory T cell
Gene: Nipsnap2 (nipsnap homolog 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagy, mitochondrion organization, mitophagy, positive regulation of high voltage-gated calcium channel activity; MF: molecular_function, protein-macromolecule adaptor activity; CC: cyt...
Does Knockout of Gabbr1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Gabbr1
cell proliferation
Embryonic Stem Cell Line
Gene: Gabbr1 (gamma-aminobutyric acid type B receptor subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, gamma-aminobutyric acid signaling path...
Does Knockout of Klhl33 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Klhl33
cell cycle progression
breast epithelium
Gene: Klhl33 (kelch-like 33) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: G3UW92, A0A2I3BRZ3, B7ZMY3 Entrez ID: 546611
Does Knockout of Pfn4 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Pfn4
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Pfn4 (profilin family, member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acrosome assembly, cell differentiation, flagellated sperm motility, manchette assembly, sperm flagellum assembly, spermatogenesis; MF: actin binding, actin monomer binding, lipid bindi...
Does Knockout of Saa1 in Embryonic Fibroblast Cell Line causally result in cell proliferation?
0
345
Knockout
Saa1
cell proliferation
Embryonic Fibroblast Cell Line
Gene: Saa1 (serum amyloid A 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acute-phase response, cholesterol metabolic process, response to bacterium; MF: G protein-coupled receptor binding, heparin binding, protein binding; CC: cytoplasmic microtubule, extracellular ...
Does Knockout of Fkbp5 in Melanoma Cell Line causally result in protein/peptide accumulation?
0
1,839
Knockout
Fkbp5
protein/peptide accumulation
Melanoma Cell Line
Gene: Fkbp5 (FK506 binding protein 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, phosphatidylinositol 3-kinase/protein kinase B signal transduction, protein folding, response t...
Does Knockout of Kctd18 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Kctd18
protein/peptide distribution
myoblast cell line
Gene: Kctd18 (potassium channel tetramerisation domain containing 18) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, protein homooligomerization Pathways: UniProt: E9Q945, E0CZ26, Q6DI85, E9PYP3, E0CXJ5 Entrez ID: 51960
Does Knockout of Dab1 in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Dab1
response to bacteria
renal medulla cell line
Gene: Dab1 (disabled 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi localization, adult walking behavior, cell differentiation, cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration, central nervous s...
Does Knockout of Ugt1a6b in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Ugt1a6b
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ugt1a6b (UDP glucuronosyltransferase 1 family, polypeptide A6B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 4-chlorobiphenyl metabolic process, cellular response to glucocorticoid stimulus, xenobiotic metabolic process; MF: UDP-glycosyltransferase activity, enzy...
Does Knockout of Acadvl in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,170
Knockout
Acadvl
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Acadvl (acyl-Coenzyme A dehydrogenase, very long chain) Type: protein-coding Summary: This gene encodes a homodimeric mitochondrial flavoprotein and is a member of the acyl-CoA dehydrogenase family. Members of this family catalyze the first step of fatty acid beta-oxidation, forming a C2-C3 trans-...
Does Knockout of Celf1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Celf1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Celf1 (CUGBP, Elav-like family member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, cerebral cortex development, cerebral cortex neuron differentiation, mRNA destabilization, mRNA processing, mRNA splice site recognition, negative regulation of ce...
Does Knockout of Tpsb2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Tpsb2
cell proliferation
Mouse kidney carcinoma cell
Gene: Tpsb2 (tryptase beta 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: inflammatory response, proteolysis; MF: heparin binding, hydrolase activity, identical protein binding, peptidase activity, protein binding, serine-type endopeptidase activity, serine-type pepti...
Does Knockout of Plekha6 in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Plekha6
cell proliferation
Melanoma Cell Line
Gene: Plekha6 (pleckstrin homology domain containing, family A member 6) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: Metabolism, Metabolism of lipids, PI Metabolism, Phospholipid metabolism, Synthesis of PIPs at the plasma membrane UniProt: Q7...
Does Knockout of Kif21a in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Kif21a
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Kif21a (kinesin family member 21A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterograde axonal transport, cortical microtubule organization, microtubule-based movement, regulation of axon guidance, regulation of microtubule depolymerization, regulation of mic...
Does Knockout of Lyz1 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Lyz1
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Lyz1 (lysozyme 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to Gram-negative bacterium, defense response to Gram-positive bacterium, defense response to bacterium, killing of cells of another organism; MF: catalytic activity, hydrolase activit...
Does Knockout of Rps6kl1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Rps6kl1
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rps6kl1 (ribosomal protein S6 kinase-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, kinase activity, nucleotide binding, protein kinase activity, protein serine kinase activity, protein serine/threonine kinase activity, transferase activity; CC...
Does Knockout of Gm20867 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Gm20867
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gm20867 (predicted gene, 20867) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q5FWD4 Entrez ID: 100041256
Does Knockout of Scgb2b12 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Scgb2b12
cell cycle progression
breast epithelium
Gene: Scgb2b12 (secretoglobin, family 2B, member 12) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, extracellular region, extracellular space Pathways: UniProt: S4R2L0 Entrez ID: 668379
Does Knockout of Rab3a in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Rab3a
cell proliferation
Mouse kidney carcinoma cell
Gene: Rab3a (RAB3A, member RAS oncogene family) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acrosomal vesicle exocytosis, axonogenesis, calcium-ion regulated exocytosis, establishment of localization in cell, evoked neurotransmitter secretion, exocytosis, insulin secr...
Does Knockout of Nampt in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,308
Knockout
Nampt
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Nampt (nicotinamide phosphoribosyltransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NAD+ biosynthetic process, NAD+ biosynthetic process via the salvage pathway, NADP+ biosynthetic process, circadian regulation of gene expression, circadian rhythm, inflam...
Does Knockout of Akr1b8 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Akr1b8
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Akr1b8 (aldo-keto reductase family 1, member B8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid metabolic process, polyol metabolic process, retinal metabolic process, retinol metabolic process; MF: NADP+ binding, NADPH binding, alcohol dehydrogenase (NADP+) ...
Does Knockout of Lhx8 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Lhx8
protein/peptide accumulation
Embryonic Cell Line
Gene: Lhx8 (LIM homeobox protein 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: female gonad development, forebrain neuron development, forebrain neuron differentiation, learning or memory, neuron differentiation, odontogenesis of dentin-containing tooth, regulation o...
Does Knockout of Slc17a3 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Slc17a3
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Slc17a3 (solute carrier family 17 (sodium phosphate), member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic anion transmembrane transport, monoatomic ion transport, organic anion transport, sodium ion transport, transmembrane transport, urate metaboli...
Does Knockout of Dmrtc1b in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Dmrtc1b
cell proliferation
Embryonic Stem Cell Line
Gene: Dmrtc1b (DMRT-like family C1b) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding; CC: nucleus Pathways: UniP...
Does Knockout of Jmjd8 in cardiac muscle cell line causally result in protein/peptide accumulation?
0
1,662
Knockout
Jmjd8
protein/peptide accumulation
cardiac muscle cell line
Gene: Jmjd8 (jumonji domain containing 8) Type: protein-coding Summary: Predicted to enable cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within cellular respiration and sprouting angiogenesis. Is active in cytoplasm. Is expressed in brain; gonad; lung; metanephros; a...
Does Knockout of Atp6v0a1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Atp6v0a1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Atp6v0a1 (ATPase, H+ transporting, lysosomal V0 subunit A1) Type: protein-coding Summary: Predicted to enable ATPase binding activity. Involved in synaptic vesicle lumen acidification. Located in perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; geni...
Does Knockout of Btbd35f11 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,308
Knockout
Btbd35f11
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Btbd35f11 (BTB domain containing 35, family member 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, germ cell development Pathways: UniProt: A2BFZ7 Entrez ID: 668958
Does Knockout of Atp13a5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Atp13a5
cell proliferation
Mouse kidney carcinoma cell
Gene: Atp13a5 (ATPase type 13A5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular calcium ion homeostasis, monoatomic cation transmembrane transport, monoatomic ion transmembrane transport, polyamine transmembrane transport; MF: ATP binding, ATP hydrolysis ac...
Does Knockout of Kidins220 in Melanoma Cell Line causally result in cell proliferation?
0
2,488
Knockout
Kidins220
cell proliferation
Melanoma Cell Line
Gene: Kidins220 (kinase D-interacting substrate 220) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to nerve growth factor stimulus, dendrite morphogenesis, in utero embryonic development, nerve growth factor signaling pathway, nervous system developmen...
Does Knockout of Ly6g5b in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,260
Knockout
Ly6g5b
cell proliferation
Mouse kidney carcinoma cell
Gene: Ly6g5b (lymphocyte antigen 6 family member G5B) Type: protein-coding Summary: Predicted to enable identical protein binding activity. Colocalizes with external side of plasma membrane. Is expressed in several structures, including brain; liver; lung; metanephros; and spleen. Orthologous to human L...
Does Knockout of Mrgpra3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,279
Knockout
Mrgpra3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Mrgpra3 (MAS-related GPR, member A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, acute-phase response, cell surface receptor signaling pathway, chemosensory behavior, response to chloroquine, signal transduction; MF:...
Does Knockout of 4930423O20Rik in macrophage causally result in phagocytosis?
0
1,890
Knockout
4930423O20Rik
phagocytosis
macrophage
Gene: 4930423O20Rik (RIKEN cDNA 4930423O20 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 73946
Does Knockout of Cd5 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Cd5
protein/peptide accumulation
Regulatory T cell
Gene: Cd5 (CD5 antigen) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell costimulation, apoptotic signaling pathway; CC: cell surface, external side of plasma membrane, membrane, plasma membrane Pathways: Hematopoietic cell lineage - Mus musculus (mouse) ...
Does Knockout of Swsap1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Swsap1
cell proliferation
Mouse kidney carcinoma cell
Gene: Swsap1 (SWIM type zinc finger 7 associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, double-strand break repair via homologous recombination, protein stabilization; MF: ATP hydrolysis activity, DNA...
Does Knockout of Snrpb2 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Snrpb2
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Snrpb2 (U2 small nuclear ribonucleoprotein B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome; MF: RNA binding, U1 snRNA binding, nucleic acid binding, protein binding, snRNP binding; CC: U1 snRNP, U2 snR...
Does Knockout of Polr2j in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,268
Knockout
Polr2j
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Polr2j (polymerase (RNA) II (DNA directed) polypeptide J) Type: protein-coding Summary: Predicted to enable LRR domain binding activity. Predicted to contribute to DNA-directed RNA polymerase activity. Predicted to be involved in transcription by RNA polymerase II. Located in nucleus. Part of RNA ...
Does Knockout of Chst2 in myoblast cell line causally result in protein/peptide distribution?
0
1,680
Knockout
Chst2
protein/peptide distribution
myoblast cell line
Gene: Chst2 (carbohydrate sulfotransferase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: N-acetylglucosamine metabolic process, carbohydrate metabolic process, inflammatory response, positive regulation of leukocyte tethering or rolling, sulfur compound metabolic pro...
Does Knockout of Tsku in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,398
Knockout
Tsku
protein/peptide accumulation
Microglial Cell Line
Gene: Tsku (tsukushi, small leucine rich proteoglycan) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anatomical structure morphogenesis, anterior commissure morphogenesis, camera-type eye development, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic pr...
Does Knockout of Cep350 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Cep350
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Cep350 (centrosomal protein 350) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule anchoring, non-motile cilium assembly, protein localization to centrosome; MF: microtubule binding, protein binding; CC: cell projection, centriole, centrosome, ciliary basa...
Does Knockout of Gm5071 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Gm5071
protein/peptide distribution
Microglial Cell Line
Gene: Gm5071 (predicted gene 5071) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 278087
Does Knockout of Hepacam2 in Non-Small Cell Lung Cancer Cell Line causally result in tumorigenicity?
0
2,189
Knockout
Hepacam2
tumorigenicity
Non-Small Cell Lung Cancer Cell Line
Gene: Hepacam2 (HEPACAM family member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, centrosome cycle; CC: Golgi apparatus, Golgi membrane, centrosome, cytoplasm, cytoskeleton, membrane, midbody, mitotic spindle, nucleoplasm, spindle Pathways: ...
Does Knockout of Zfp712 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Zfp712
cell proliferation
Embryonic Stem Cell Line
Gene: Zfp712 (zinc finger protein 712) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of macromolecule biosynthetic process, regulation of DNA-templated transcription, regulation of anatomical structure morphogenesis, regulation of transcription by RN...
Does Knockout of Cyp2e1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Cyp2e1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cyp2e1 (cytochrome P450, family 2, subfamily e, polypeptide 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 4-nitrophenol metabolic process, epoxygenase P450 pathway, fatty acid metabolic process, lipid hydroxylation, lipid metabolic process, long-chain fatty aci...
Does Knockout of Artn in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Artn
response to virus
Embryonic Fibroblast Cell Line
Gene: Artn (artemin) Type: protein-coding Summary: This gene encodes a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment...
Does Knockout of Nme7 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,398
Knockout
Nme7
protein/peptide accumulation
Microglial Cell Line
Gene: Nme7 (NME/NM23 family member 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CTP biosynthetic process, DNA catabolic process, GTP biosynthetic process, UTP biosynthetic process, brain development, cellular response to leukemia inhibitory factor, cilium assembly, ...
Does Knockout of Gipr in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Gipr
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Gipr (gastric inhibitory polypeptide receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled rec...
Does Knockout of Vmn1r224 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Vmn1r224
cell proliferation
Mouse kidney carcinoma cell
Gene: Vmn1r224 (vomeronasal 1 receptor 224) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled recepto...
Does Knockout of Rad23b in Lymphoma Cell Line causally result in response to chemicals?
1
1,543
Knockout
Rad23b
response to chemicals
Lymphoma Cell Line
Gene: Rad23b (RAD23 homolog B, nucleotide excision repair protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, UV-damage excision repair, cellular response to interleukin-7, embryonic organ development, nucleotide-excision repair, prot...
Does Knockout of Spaca4 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Spaca4
cell proliferation
Mouse kidney carcinoma cell
Gene: Spaca4 (sperm acrosome associated 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: binding of sperm to zona pellucida, cell adhesion, fertilization, single fertilization, sperm-egg recognition; CC: acrosomal vesicle, cytoplasmic vesicle, inner acrosomal membrane, ...
Does Knockout of Ankrd12 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Ankrd12
response to virus
Embryonic Fibroblast Cell Line
Gene: Ankrd12 (ankyrin repeat domain 12) Type: protein-coding Summary: Predicted to be located in cytosol. Predicted to be active in nucleoplasm. Orthologous to human ANKRD12 (ankyrin repeat domain 12). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: CC: cytosol, nucleoplasm...
Does Knockout of Dera in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Dera
response to virus
Neuroblastoma Cell Line
Gene: Dera (deoxyribose-phosphate aldolase) Type: protein-coding Summary: Predicted to enable deoxyribose-phosphate aldolase activity. Predicted to be involved in carbohydrate catabolic process; deoxyribonucleoside catabolic process; and deoxyribonucleotide catabolic process. Predicted to be located in ...