prompt
string
hit
int64
screen_id
int64
crispr_strategy
string
gene
string
phenotype
string
cell_type
string
gene_context
string
Does Knockout of Scrib in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Scrib
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Scrib (scribbled planar cell polarity) Type: protein-coding Summary: No summary available. Gene Ontology: BP: activation of GTPase activity, apoptotic process involved in morphogenesis, astrocyte cell migration, auditory receptor cell morphogenesis, auditory receptor cell stereocilium org...
Does Knockout of Tmem126b in myoblast cell line causally result in protein/peptide distribution?
0
1,685
Knockout
Tmem126b
protein/peptide distribution
myoblast cell line
Gene: Tmem126b (transmembrane protein 126B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial respiratory chain complex I assembly, mitochondrion organization, response to food; CC: membrane, mitochondrial membrane, mitochondrion Pathways: Aerobic res...
Does Knockout of Tmem114 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Tmem114
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tmem114 (transmembrane protein 114) Type: protein-coding Summary: Located in apical plasma membrane and apicolateral plasma membrane. Is expressed in several structures, including gut; heart; liver; male reproductive gland or organ; and metanephros. Orthologous to human TMEM114 (transmembrane prot...
Does Knockout of Usp36 in Embryonic Stem Cell Line causally result in cell proliferation?
1
578
Knockout
Usp36
cell proliferation
Embryonic Stem Cell Line
Gene: Usp36 (ubiquitin specific peptidase 36) Type: protein-coding Summary: Predicted to enable K48-linked deubiquitinase activity; cysteine-type deubiquitinase activity; and histone H2B deubiquitinase activity. Involved in several processes, including nucleolus organization; protein stabilization; and ...
Does Knockout of Smoc2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Smoc2
cell proliferation
Mouse kidney carcinoma cell
Gene: Smoc2 (SPARC related modular calcium binding 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: extracellular matrix organization, positive regulation of DNA biosynthetic process, positive regulation of angiogenesis, positive regulation of cell-substrate adhesion, p...
Does Knockout of Rxfp3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,279
Knockout
Rxfp3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Rxfp3 (relaxin family peptide receptor 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, neuropeptide signaling pathway, phospholipase C-activating G protein-coupled receptor signaling pathway, positive regulation of cy...
Does Knockout of Abhd5 in Melanoma Cell Line causally result in cell proliferation?
0
2,488
Knockout
Abhd5
cell proliferation
Melanoma Cell Line
Gene: Abhd5 (abhydrolase domain containing 5) Type: protein-coding Summary: Enables lipase activator activity. Involved in negative regulation of triglyceride storage and positive regulation of triglyceride catabolic process. Located in cytosol and lipid droplet. Is expressed in central nervous system; ...
Does Knockout of Cadm4 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Cadm4
protein/peptide accumulation
Embryonic Cell Line
Gene: Cadm4 (cell adhesion molecule 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules, negative regulation of peptidyl-threonine phosphorylation, negative regulation of peptidyl-tyrosine phosp...
Does Knockout of Rhox9 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Rhox9
phagocytosis
macrophage
Gene: Rhox9 (reproductive homeobox 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription activator acti...
Does Knockout of Mpz in Melanoma Cell Line causally result in tumorigenicity?
0
2,187
Knockout
Mpz
tumorigenicity
Melanoma Cell Line
Gene: Mpz (myelin protein zero) Type: protein-coding Summary: This gene is specifically expressed in Schwann cells of the peripheral nervous system and encodes a type I transmembrane glycoprotein that is a major structural protein of the peripheral myelin sheath. The encoded protein contains a large hyd...
Does Knockout of B3gnt9 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,279
Knockout
B3gnt9
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: B3gnt9 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: poly-N-acetyllactosamine biosynthetic process, protein O-linked glycosylation, protein glycosylation; MF: UDP-glycosyltransferase activity, glycosy...
Does Knockout of Ddt in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Ddt
cell proliferation
Colonic Cancer Cell Line
Gene: Ddt (D-dopachrome tautomerase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: melanin biosynthetic process, positive regulation of inflammatory response; MF: D-dopachrome decarboxylase activity, cytokine receptor binding, lyase activity, phenylpyruvate tautomerase ...
Does Knockout of Trim54 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Trim54
cell proliferation
Mouse kidney carcinoma cell
Gene: Trim54 (tripartite motif-containing 54) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, innate immune response, negative regulation of microtubule depolymerization; MF: metal ion binding, microtubule binding, protein binding, ubiquitin protein ...
Does Knockout of Cd3e in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Cd3e
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Cd3e (CD3 antigen, epsilon polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell costimulation, T cell receptor signaling pathway, adaptive immune response, apoptotic signaling pathway, cell surface receptor signaling pathway, cerebellum development, d...
Does Knockout of Mtif2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Mtif2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mtif2 (mitochondrial translational initiation factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translational initiation, ribosome disassembly, translation, translational initiation; MF: GTP binding, GTPase activity, nucleotide binding, ribosom...
Does Knockout of Twnk in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Twnk
cell proliferation
Regulatory T cell
Gene: Twnk (twinkle mtDNA helicase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, DNA-templated DNA replication, mitochondrial DNA replication, mitochondrial transcription, protein hexamerization; MF: 5'-3' DNA helicase activity, ATP binding, ATP hydrol...
Does Knockout of Zfr2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,259
Knockout
Zfr2
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfr2 (zinc finger RNA binding protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: double-stranded RNA binding, molecular_function, nucleic acid binding, single-stranded RNA binding, zinc ion binding Pathways: UniProt: F6VRB4, E9Q5M4, D3YXQ2...
Does Knockout of Epyc in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Epyc
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Epyc (epiphycan) Type: protein-coding Summary: No summary available. Gene Ontology: BP: articular cartilage development, bone development, sensory perception of sound; CC: extracellular matrix, extracellular region Pathways: UniProt: P70186 Entrez ID: 13516
Does Knockout of Lgalsl in myoblast cell line causally result in protein/peptide distribution?
0
1,683
Knockout
Lgalsl
protein/peptide distribution
myoblast cell line
Gene: Lgalsl (galectin like) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carbohydrate binding, molecular_function Pathways: UniProt: Q8VED9 Entrez ID: 216551
Does Knockout of Sfxn5 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Sfxn5
protein/peptide accumulation
Embryonic Cell Line
Gene: Sfxn5 (sideroflexin 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: amino acid transport, citrate transport, mitochondrial transmembrane transport, monoatomic ion transmembrane transport, monoatomic ion transport, positive regulation of cold-induced thermogenesis...
Does Knockout of Sec62 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Sec62
cell cycle progression
breast epithelium
Gene: Sec62 (SEC62 homolog, preprotein translocation) Type: protein-coding Summary: No summary available. Gene Ontology: BP: post-translational protein targeting to endoplasmic reticulum membrane, post-translational protein targeting to membrane, translocation, protein transport; CC: endoplasmi...
Does Knockout of Slc4a2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Slc4a2
protein/peptide accumulation
Embryonic Cell Line
Gene: Slc4a2 (solute carrier family 4 (anion exchanger), member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: amelogenesis, bicarbonate transport, cell differentiation, chloride transmembrane transport, chloride transport, monoatomic anion transmembrane transport, mo...
Does Knockout of Ruvbl1 in Lung Cancer Cell Line causally result in tumorigenicity?
1
1,089
Knockout
Ruvbl1
tumorigenicity
Lung Cancer Cell Line
Gene: Ruvbl1 (RuvB-like AAA ATPase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, box C/D snoRNP assembly, cell division, chromatin organization, chromatin remodeling, positive regulation of DNA repair, positive regu...
Does Knockout of Atp8b5 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Atp8b5
protein/peptide distribution
Microglial Cell Line
Gene: Atp8b5 (ATPase, class I, type 8B, member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, lipid transport, phospholipid translocation, phospholipid transport; MF: ATP binding, ATP hydrolysis activity, ATPase-coupled intramembrane lipid transpor...
Does Knockout of 2310022B05Rik in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
1,565
Knockout
2310022B05Rik
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: 2310022B05Rik (RIKEN cDNA 2310022B05 gene) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, cytosol Pathways: UniProt: Q8C3W1 Entrez ID: 69551
Does Knockout of Apol10b in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Apol10b
cell proliferation
Mouse kidney carcinoma cell
Gene: Apol10b (apolipoprotein L 10B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, lipid transport, lipoprotein metabolic process; MF: chloride channel activity, lipid binding, molecular_function; CC: extracellular region, extracellular space, high-d...
Does Knockout of Cdh1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Cdh1
protein/peptide accumulation
Embryonic Cell Line
Gene: Cdh1 (cadherin 1) Type: protein-coding Summary: This gene encodes E-cadherin, a calcium-dependent cell adhesion molecule that functions in the establishment and maintenance of epithelial cell morphology during embryongenesis and adulthood. The encoded preproprotein undergoes proteolytic processing...
Does Knockout of 2310009B15Rik in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,259
Knockout
2310009B15Rik
cell proliferation
Mouse kidney carcinoma cell
Gene: 2310009B15Rik (RIKEN cDNA 2310009B15 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A0A0A6YWI4, D3Z1T2 Entrez ID: 69549
Does Knockout of Stab2 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Stab2
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Stab2 (stabilin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, defense response to Gram-positive bacterium, defense response to bacterium, endocytosis, hyaluronan catabolic process, receptor-mediated endocytosis; MF: calcium ion binding, cargo rec...
Does Knockout of Zfp960 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
163
Knockout
Zfp960
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Zfp960 (zinc finger protein 960) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Tsku in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Tsku
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Tsku (tsukushi, small leucine rich proteoglycan) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anatomical structure morphogenesis, anterior commissure morphogenesis, camera-type eye development, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic pr...
Does Knockout of Fgf17 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Fgf17
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Fgf17 (fibroblast growth factor 17) Type: protein-coding Summary: Predicted to enable growth factor activity; type 1 fibroblast growth factor receptor binding activity; and type 2 fibroblast growth factor receptor binding activity. Acts upstream of or within fibroblast growth factor receptor signa...
Does Knockout of Adam5 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Adam5
protein/peptide distribution
myoblast cell line
Gene: Adam5 (a disintegrin and metallopeptidase domain 5) Type: protein-coding Summary: This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. The encoded p...
Does Knockout of Arpc5 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Arpc5
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Arpc5 (actin related protein 2/3 complex, subunit 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Arp2/3 complex-mediated actin nucleation, actin filament network formation, cell migration, lamellipodium organization, maintenance of cell polarity, microtubule org...
Does Knockout of Clca2 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Clca2
protein/peptide distribution
myoblast cell line
Gene: Clca2 (chloride channel accessory 2) Type: protein-coding Summary: This gene encodes a member of the calcium-activated chloride channel regulator (CLCR) family of proteins. Members of this family regulate the transport of chloride across the plasma membrane. Expression of this gene is upregulated ...
Does Knockout of Dkkl1 in pro-B-lymphocyte causally result in response to chemicals?
0
1,720
Knockout
Dkkl1
response to chemicals
pro-B-lymphocyte
Gene: Dkkl1 (dickkopf-like 1) Type: protein-coding Summary: Predicted to enable co-receptor binding activity and receptor antagonist activity. Involved in negative regulation of testosterone biosynthetic process; penetration of zona pellucida; and positive regulation of apoptotic process. Acts upstream ...
Does Knockout of Far2 in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Far2
cell proliferation
Regulatory T cell
Gene: Far2 (fatty acyl CoA reductase 2) Type: protein-coding Summary: Enables alcohol-forming very long-chain fatty acyl-CoA reductase activity. Predicted to be involved in long-chain fatty-acyl-CoA metabolic process. Predicted to act upstream of or within wax biosynthetic process. Located in peroxisome...
Does Knockout of Apbb1ip in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Apbb1ip
cell proliferation
Mouse kidney carcinoma cell
Gene: Apbb1ip (amyloid beta precursor protein binding family B member 1 interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell, positive regulation of...
Does Knockout of Grin2b in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,263
Knockout
Grin2b
cell proliferation
Colonic Cancer Cell Line
Gene: Grin2b (glutamate receptor, ionotropic, NMDA2B (epsilon 2)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: action potential, associative learning, behavioral fear response, behavioral response to pain, calcium ion transmembrane import into cytosol, calcium ion tran...
Does Knockout of Snx10 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
1,664
Knockout
Snx10
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Snx10 (sorting nexin 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bone mineralization involved in bone maturation, bone remodeling, bone resorption, calcium ion homeostasis, cell projection organization, cellular homeostasis, cellular response to leukemia inh...
Does Knockout of Cdk17 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Cdk17
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cdk17 (cyclin dependent kinase 17) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, cyclin-dependent protein serine/threonine kinase activity, kinase activity, nucleotide binding, protein kinase activity, protein serine kinase activity, protein serine/th...
Does Knockout of Umodl1 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Umodl1
protein/peptide distribution
myoblast cell line
Gene: Umodl1 (uromodulin-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adipose tissue development, cellular response to gonadotropin-releasing hormone, ectopic germ cell programmed cell death, regulation of apoptotic process, regulation of developmental process,...
Does Knockout of Cib2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Cib2
protein/peptide accumulation
Embryonic Cell Line
Gene: Cib2 (calcium and integrin binding family member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion homeostasis, cellular response to ATP, photoreceptor cell maintenance, positive regulation of cytosolic calcium ion concentration; MF: calcium ion binding...
Does Knockout of Mrps35 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Mrps35
cell proliferation
Colonic Cancer Cell Line
Gene: Mrps35 (mitochondrial ribosomal protein S35) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation; MF: structural constituent of ribosome; CC: cytosol, mitochondrial inner membrane, mitochondrial small ribosomal subunit, mitochondrion, ribonucle...
Does Knockout of Rgs13 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Rgs13
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Rgs13 (regulator of G-protein signaling 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, negative regulation of G protein-coupled receptor signaling pathway, negative regulation of signal transduction; CC: cytosol, nu...
Does Knockout of Nudt2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Nudt2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nudt2 (nudix hydrolase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: AMP biosynthetic process, ATP biosynthetic process, apoptotic process; MF: GTP binding, bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity, bis(5'-nucleosyl)-tetraphosphatase activity,...
Does Knockout of Zbtb34 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Zbtb34
cell cycle progression
breast epithelium
Gene: Zbtb34 (zinc finger and BTB domain containing 34) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, regulation of cytokine production, regulation of immune system process; MF: DNA binding, DNA-binding transcri...
Does Knockout of Ncapd2 in macrophage causally result in phagocytosis?
0
1,890
Knockout
Ncapd2
phagocytosis
macrophage
Gene: Ncapd2 (non-SMC condensin I complex, subunit D2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, chromosome condensation, meiotic chromosome condensation, mitotic cell cycle, mitotic chromosome condensation, positive regulation of chromosome condensat...
Does Knockout of T in Melanoma Cell Line causally result in cell proliferation?
0
1,838
Knockout
T
cell proliferation
Melanoma Cell Line
Gene: T (brachyury, T-box transcription factor T) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anatomical structure morphogenesis, anterior/posterior pattern specification, bone morphogenesis, cardiac muscle cell differentiation, cardiac muscle cell myoblast differenti...
Does Knockout of Arsb in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Arsb
cell proliferation
Embryonic Stem Cell Line
Gene: Arsb (arylsulfatase B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterior head development, autophagy, chondroitin sulfate proteoglycan catabolic process, colon epithelial cell migration, dermatan sulfate proteoglycan catabolic process, positive regulation of ...
Does Knockout of Clic1 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Clic1
cell cycle progression
breast epithelium
Gene: Clic1 (chloride intracellular channel 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chloride transmembrane transport, chloride transport, monoatomic ion transmembrane transport, monoatomic ion transport, positive regulation of osteoblast differentiation, regula...
Does Knockout of Gast in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Gast
response to virus
Neuroblastoma Cell Line
Gene: Gast (gastrin) Type: protein-coding Summary: This gene encodes the peptide hormone gastrin, which stimulates gastric acid secretion, proliferation, cell migration and angiogenesis, as well as inhibits apoptosis. The encoded preproprotein undergoes proteolytic processing to generate multiple gastri...
Does Knockout of Magee2 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Magee2
protein/peptide distribution
myoblast cell line
Gene: Magee2 (MAGE family member E2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, brain morphogenesis, negative regulation of transcription by RNA polymerase II Pathways: UniProt: Q8CBC3, Q52KG3 Entrez ID: 272790
Does Knockout of Myo1c in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Myo1c
cell proliferation
Embryonic Stem Cell Line
Gene: Myo1c (myosin IC) Type: protein-coding Summary: This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The protein functions in int...
Does Knockout of Gnat1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Gnat1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Gnat1 (G protein subunit alpha transducin 1) Type: protein-coding Summary: Enables G-protein beta/gamma-subunit complex binding activity and GTPase activity. Acts upstream of or within several processes, including cellular response to electrical stimulus; detection of light stimulus; and eye photo...
Does Knockout of Apcdd1 in myoblast cell line causally result in protein/peptide distribution?
1
1,681
Knockout
Apcdd1
protein/peptide distribution
myoblast cell line
Gene: Apcdd1 (adenomatosis polyposis coli down-regulated 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, astrocyte cell migration, hair follicle development, negative regulation of Wnt signaling pathway, regulation of odontogenesis of dentin-cont...
Does Knockout of Htr1b in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
1
2,308
Knockout
Htr1b
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Htr1b (5-hydroxytryptamine (serotonin) receptor 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, adenylate cyclase-inhibitin...
Does Knockout of Mocs3 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,290
Knockout
Mocs3
cell proliferation
Mouse kidney carcinoma cell
Gene: Mocs3 (molybdenum cofactor synthesis 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Mo-molybdopterin cofactor biosynthetic process, molybdopterin cofactor biosynthetic process, protein urmylation, tRNA processing, tRNA thio-modification, tRNA wobble position uri...
Does Knockout of Car15 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Car15
protein/peptide accumulation
Embryonic Cell Line
Gene: Car15 (carbonic anhydrase 15) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carbonate dehydratase activity, lyase activity, metal ion binding, zinc ion binding; CC: extracellular region, membrane, plasma membrane Pathways: Nitrogen metabolism - Mus muscul...
Does Knockout of Dysf in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
1,565
Knockout
Dysf
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Dysf (dysferlin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T-tubule organization, angiogenesis, cellular response to osmotic stress, fat cell differentiation, glycerol metabolic process, lipid storage, macrophage activation involved in immune response, membran...
Does Knockout of Ctdsp2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Ctdsp2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Ctdsp2 (CTD small phosphatase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of G1/S transition of mitotic cell cycle, regulation of transcription by RNA polymerase II; MF: RNA polymerase II CTD heptapeptide repeat phosphatase activity, hydro...
Does Knockout of Tkfc in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Tkfc
cell proliferation
Embryonic Stem Cell Line
Gene: Tkfc (triokinase, FMN cyclase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate metabolic process, carbohydrate phosphorylation, fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate, glycerol catabolic process, glycerol m...
Does Knockout of Cdc7 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Cdc7
cell proliferation
Mouse kidney carcinoma cell
Gene: Cdc7 (cell division cycle 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell cycle phase transition, cell division, double-strand break repair via break-induced replication, positive regulation of G2/M transition of mitotic cell cycle, positive regulation of ce...
Does Knockout of Chuk in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,266
Knockout
Chuk
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Chuk (conserved helix-loop-helix ubiquitous kinase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: canonical NF-kappaB signal transduction, cellular response to tumor necrosis factor, cellular response to virus, defense response to virus, integrin-mediated signalin...
Does Knockout of Pou5f1 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Pou5f1
protein/peptide accumulation
Mouse cell
Gene: Pou5f1 (POU domain, class 5, transcription factor 1) Type: protein-coding Summary: The protein encoded by this gene belongs to the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathw...
Does Knockout of Rbm11 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Rbm11
cell proliferation
Melanoma Cell Line
Gene: Rbm11 (RNA binding motif protein 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, cell differentiation, cellular response to oxidative stress, mRNA processing, regulation of alternative mRNA splicing, via spliceosome; MF: RNA binding, nucleic acid b...
Does Knockout of Coro1c in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Coro1c
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Coro1c (coronin, actin binding protein 1C) Type: protein-coding Summary: Enables small GTPase binding activity. Involved in several processes, including activation of GTPase activity; regulation of fibroblast migration; and regulation of ruffle assembly. Acts upstream of or within corpus callosum ...
Does Knockout of Rell2 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Rell2
cell viability
Immortal mouse chromaffin cells
Gene: Rell2 (RELT-like 2) Type: protein-coding Summary: Enables collagen binding activity. Acts upstream of or within positive regulation of cell-substrate adhesion. Located in basement membrane. Is expressed in lip; lower jaw molar dental lamina; lower jaw molar enamel organ; and oral epithelium. Ortho...
Does Knockout of Ppbp in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Ppbp
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ppbp (pro-platelet basic protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antimicrobial humoral immune response mediated by antimicrobial peptide, cellular response to lipopolysaccharide, chemotaxis, defense response, immune response, inflammatory response, ...
Does Knockout of R3hdml in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
R3hdml
response to virus
Embryonic Fibroblast Cell Line
Gene: R3hdml (R3H domain containing-like) Type: protein-coding Summary: No summary available. Gene Ontology: MF: molecular_function, peptidase inhibitor activity; CC: extracellular region, extracellular space Pathways: UniProt: A2A5I3 Entrez ID: 100043899
Does Knockout of Rtca in Melanoma Cell Line causally result in cell proliferation?
0
2,488
Knockout
Rtca
cell proliferation
Melanoma Cell Line
Gene: Rtca (RNA 3'-terminal phosphate cyclase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA processing, negative regulation of optical nerve axon regeneration; MF: ATP binding, RNA-3'-phosphate cyclase activity, catalytic activity, ligase activity, nucleotide bindi...
Does Knockout of Flot1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Flot1
cell proliferation
Colonic Cancer Cell Line
Gene: Flot1 (flotillin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adherens junction organization, axon guidance, axonogenesis, caveola assembly, cell-cell adhesion mediated by cadherin, cell-cell junction assembly, endocytosis, extracellular matrix disassembly, in...
Does Knockout of Hcar2 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Hcar2
protein/peptide distribution
myoblast cell line
Gene: Hcar2 (hydroxycarboxylic acid receptor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, apoptotic process, negative regulation of lipid catabolic process, positive regulation of adiponectin secretion, positive regulati...
Does Knockout of Gabra6 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Gabra6
cell proliferation
Embryonic Stem Cell Line
Gene: Gabra6 (gamma-aminobutyric acid type A receptor subunit alpha 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chloride transmembrane transport, chloride transport, gamma-aminobutyric acid signaling pathway, inhibitory synapse assembly, monoatomic ion transmembran...
Does Knockout of Syce2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
1,664
Knockout
Syce2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Syce2 (synaptonemal complex central element protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, meiotic cell cycle, synaptonemal complex assembly; CC: central element, chromosome, nucleoplasm, nucleus, synaptonemal complex Pathways: ...
Does Knockout of Gm17175 in Embryonic Fibroblast Cell Line causally result in cell proliferation?
1
345
Knockout
Gm17175
cell proliferation
Embryonic Fibroblast Cell Line
Gene: Gm17175 (predicted gene 17175) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 102641463
Does Knockout of Gpr88 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Gpr88
cell proliferation
Embryonic Stem Cell Line
Gene: Gpr88 (G-protein coupled receptor 88) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-modulating G protein-coupled receptor signaling pathway, adrenergic receptor signaling pathway, cellular response to...
Does Knockout of Epha3 in Melanoma Cell Line causally result in cell proliferation?
0
1,838
Knockout
Epha3
cell proliferation
Melanoma Cell Line
Gene: Epha3 (Eph receptor A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axon guidance, cell migration, cell surface receptor protein tyrosine kinase signaling pathway, cellular response to follicle-stimulating hormone stimulus, cellular response to retinoic acid, en...
Does Knockout of Mplkip in Melanoma Cell Line causally result in cell proliferation?
0
1,281
Knockout
Mplkip
cell proliferation
Melanoma Cell Line
Gene: Mplkip (M-phase specific PLK1 intereacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: CC: Golgi apparatus, centrosome, cytoplasm, cytoskeleton, midbody, nucleoplasm, nucleus Pathways: UniProt: Q9D011 Entrez ID: 66308
Does Knockout of Ercc8 in Lymphoma Cell Line causally result in response to chemicals?
0
1,559
Knockout
Ercc8
response to chemicals
Lymphoma Cell Line
Gene: Ercc8 (excision repaiross-complementing rodent repair deficiency, complementation group 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, double-strand break repair via classical nonhomologous end joining, positive regulation of DNA...
Does Knockout of Hmbox1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Hmbox1
cell proliferation
Colonic Cancer Cell Line
Gene: Hmbox1 (homeobox containing 1) Type: protein-coding Summary: Enables telomeric DNA binding activity. Involved in telomere maintenance via telomerase. Located in chromosome, telomeric region and nucleus. Is expressed in several structures, including central nervous system; early conceptus; female r...
Does Knockout of Cobll1 in myoblast cell line causally result in protein/peptide distribution?
0
1,683
Knockout
Cobll1
protein/peptide distribution
myoblast cell line
Gene: Cobll1 (Cobl-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cell cortex, membrane Pathways: UniProt: Q3UMF0 Entrez ID: 319876
Does Knockout of Tubal3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,268
Knockout
Tubal3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Tubal3 (tubulin, alpha-like 3) Type: protein-coding Summary: Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be active in cytoplasm and microtu...
Does Knockout of Tmem132d in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Tmem132d
cell proliferation
Mouse kidney carcinoma cell
Gene: Tmem132d (transmembrane protein 132D) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q76HP3 Entrez ID: 243274
Does Knockout of Tppp2 in myoblast cell line causally result in protein/peptide distribution?
1
1,679
Knockout
Tppp2
protein/peptide distribution
myoblast cell line
Gene: Tppp2 (tubulin polymerization-promoting protein family member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, microtubule bundle formation, microtubule polymerization, positive regulation of protein polymerization, regulation of flagellated ...
Does Knockout of Vmn2r15 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,398
Knockout
Vmn2r15
protein/peptide accumulation
Microglial Cell Line
Gene: Vmn2r15 (vomeronasal 2, receptor 15) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: A0A3B...
Does Knockout of Tbc1d21 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Tbc1d21
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Tbc1d21 (TBC1 domain family, member 21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, flagellated sperm motility, plasma membrane to endosome transport, sperm axoneme assembly, sperm mitochondrial sheath assembly, spermatogenesis; MF: GTPase ...
Does Knockout of Spats2l in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Spats2l
cell proliferation
Mouse kidney carcinoma cell
Gene: Spats2l (spermatogenesis associated, serine-rich 2-like) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, cytosol, nucleolus, nucleoplasm, nucleus, protein-containing complex Pathways: UniProt: Q91WJ7 Entrez ID: 67198
Does Knockout of Prl3b1 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Prl3b1
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Prl3b1 (prolactin family 3, subfamily b, member 1) Type: protein-coding Summary: Predicted to enable hormone activity and prolactin receptor binding activity. Predicted to be involved in several processes, including female pregnancy; positive regulation of lactation; and positive regulation of rec...
Does Knockout of Serpinb9c in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Serpinb9c
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Serpinb9c (serine (or cysteine) peptidase inhibitor, clade B, member 9c) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cytoplasm, extracellular space Pathways: Amoebiasis - Mus musculus (mouse) UniProt: I7HJI5, Q9D6A7, Q80WW4, J3JSA2 Entr...
Does Knockout of Slc6a11 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
1,664
Knockout
Slc6a11
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Slc6a11 (solute carrier family 6 (neurotransmitter transporter, GABA), member 11) Type: protein-coding Summary: Enables gamma-aminobutyric acid:sodium:chloride symporter activity and taurine:sodium symporter activity. Involved in neurotransmitter uptake. Is active in synapse. Is expressed in sever...
Does Knockout of Ube2t in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,170
Knockout
Ube2t
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ube2t (ubiquitin-conjugating enzyme E2T) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, protein K11-linked ubiquitination, protein K27-linked ubiquitination, protein K29-linked ubiquitination, protein K48-linked ubiquitination, prot...
Does Knockout of Ppp1r3c in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,263
Knockout
Ppp1r3c
cell proliferation
Colonic Cancer Cell Line
Gene: Ppp1r3c (protein phosphatase 1, regulatory subunit 3C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glycogen biosynthetic process, glycogen metabolic process, protein targeting, regulation of glycogen biosynthetic process, regulation of glycogen catabolic process...
Does Knockout of Cln3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,266
Knockout
Cln3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cln3 (CLN3 lysosomal/endosomal transmembrane protein, battenin) Type: protein-coding Summary: This gene encodes a transmembrane protein called battenin that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis genes, cause a number of neurodegenerat...
Does Knockout of Tmem35b in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Tmem35b
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Tmem35b (transmembrane protein 35B) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q3U0Y2 Entrez ID: 100039968
Does Knockout of Bsn in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Bsn
cell proliferation
Mouse kidney carcinoma cell
Gene: Bsn (bassoon) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axo-dendritic transport, maintenance of presynaptic active zone structure, modulation of chemical synaptic transmission, presynaptic active zone assembly, presynaptic active zone organization, protein loc...
Does Knockout of Slc11a1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Slc11a1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Slc11a1 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-arginine transmembrane transport, MHC class II biosynthetic process, T cell proliferation involved in immune response, ant...
Does Knockout of Mpzl2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Mpzl2
cell proliferation
Mouse kidney carcinoma cell
Gene: Mpzl2 (myelin protein zero-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell differentiation in thymus, cell adhesion, cell-cell adhesion; CC: membrane, plasma membrane Pathways: UniProt: A0A1L1STN6, F6RG10, A0A1L1SST8 Entrez ...
Does Knockout of Rad54l2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Rad54l2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rad54l2 (RAD54 like 2 (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, positive regulation of transcription by RNA polymerase II; MF: ATP binding, ATP hydrolysis activity, ATP-dependent chromatin remodele...
Does Knockout of Ift46 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Ift46
cell proliferation
Mouse kidney carcinoma cell
Gene: Ift46 (intraflagellar transport 46) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axoneme assembly, cilium assembly, cilium organization, cilium-dependent cell motility, intraciliary anterograde transport, intraciliary transport, protein transport, regulation of c...