prompt
string
hit
int64
screen_id
int64
crispr_strategy
string
gene
string
phenotype
string
cell_type
string
gene_context
string
Does Knockout of Pcdhga9 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Pcdhga9
cell proliferation
Mouse kidney carcinoma cell
Gene: Pcdhga9 (protocadherin gamma subfamily A, 9) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding, metal ion binding; CC: membrane, pla...
Does Knockout of Cavin3 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,277
Knockout
Cavin3
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cavin3 (caveolae associated 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: circadian regulation of gene expression, cortical actin cytoskeleton organization, negative regulation of fermentation, negative regulation of phosphatidylinositol 3-kinase/protein kinase...
Does Knockout of Rnf26 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Rnf26
protein/peptide distribution
myoblast cell line
Gene: Rnf26 (ring finger protein 26) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endosome organization, negative regulation of defense response to virus, protein K11-linked ubiquitination, protein localization to perinuclear region of cytoplasm, protein ubiquitination...
Does Knockout of Gmeb1 in Regulatory T cell causally result in cell proliferation?
0
1,483
Knockout
Gmeb1
cell proliferation
Regulatory T cell
Gene: Gmeb1 (glucocorticoid modulatory element binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription activa...
Does Knockout of Il4i1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Il4i1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Il4i1 (interleukin 4 induced 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-phenylalanine catabolic process, L-tryptophan catabolic process, L-tryptophan catabolic process to indole-3-acetate, L-tyrosine catabolic process, adaptive immune response, amino acid ...
Does Knockout of Sik2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Sik2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Sik2 (salt inducible kinase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, insulin receptor signaling pathway, intracellular signal transduction, lipid biosynthetic process, negative regulation of carbohydrate metabolic process, negative regulation...
Does Knockout of Senp5 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,481
Knockout
Senp5
protein/peptide accumulation
Regulatory T cell
Gene: Senp5 (SUMO/sentrin specific peptidase 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, protein desumoylation, proteolysis; MF: SUMO-specific endopeptidase activity, cysteine-type peptidase activity, deSUMOylase activity, hydrolase activity, peptida...
Does Knockout of Prm3 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Prm3
protein/peptide accumulation
Regulatory T cell
Gene: Prm3 (protamine 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, chromosome condensation, flagellated sperm motility, spermatogenesis; CC: chromosome, cytoplasm, nucleosome, nucleus Pathways: UniProt: Q62100 Entrez ...
Does Knockout of Cenpc1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Cenpc1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cenpc1 (centromere protein C1) Type: protein-coding Summary: This gene encodes a centromeric protein component of a nucleosome-associated complex that plays a central role in kinetochore protein assembly, mitotic progression and chromosome segregation. The human ortholog encodes a protein with DNA...
Does Knockout of Mtss1 in myoblast cell line causally result in protein/peptide distribution?
0
1,683
Knockout
Mtss1
protein/peptide distribution
myoblast cell line
Gene: Mtss1 (MTSS I-BAR domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament organization, actin filament polymerization, adherens junction maintenance, bone mineralization, cellular response to fluid shear stress, epithelial cell proliferat...
Does Knockout of Kdm1a in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
1,666
Knockout
Kdm1a
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Kdm1a (lysine (K)-specific demethylase 1A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair-dependent chromatin remodeling, cell differentiation, cellular response to UV, cellular response to gamma radiation, chromatin organization, epigenetic regulation o...
Does Knockout of Pus7 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Pus7
cell proliferation
Colonic Cancer Cell Line
Gene: Pus7 (pseudouridylate synthase 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA modification, RNA splicing, mRNA processing, mRNA pseudouridine synthesis, negative regulation of translation, pseudouridine synthesis, regulation of hematopoietic stem cell differ...
Does Knockout of Prpf40a in macrophage causally result in phagocytosis?
0
1,890
Knockout
Prpf40a
phagocytosis
macrophage
Gene: Prpf40a (pre-mRNA processing factor 40A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, cell migration, cytoskeleton organization, mRNA cis splicing, via spliceosome, mRNA processing, mRNA splicing, via spliceosome, regulation of cell shape, regulatio...
Does Knockout of Defb37 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Defb37
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Defb37 (defensin beta 37) Type: protein-coding Summary: Predicted to enable CCR6 chemokine receptor binding activity and identical protein binding activity. Predicted to be involved in calcium-mediated signaling; defense response to other organism; and positive regulation of flagellated sperm moti...
Does Knockout of Nol8 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Nol8
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nol8 (nucleolar protein 8) Type: protein-coding Summary: Predicted to enable RNA binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in chromosome. Predicted to be active in nucleolus. Is expressed in central nervous system and sens...
Does Knockout of Pitpnc1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Pitpnc1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Pitpnc1 (phosphatidylinositol transfer protein, cytoplasmic 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intermembrane lipid transfer, lipid transport, phosphatidylinositol metabolic process, phospholipid transport, signal transduction; MF: lipid binding, phos...
Does Knockout of Onecut2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Onecut2
protein/peptide accumulation
Embryonic Cell Line
Gene: Onecut2 (one cut domain, family member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anatomical structure morphogenesis, cell fate commitment, cilium assembly, endocrine pancreas development, epithelial cell development, liver development, negative regulation o...
Does Knockout of Cacna1c in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Cacna1c
cell proliferation
Colonic Cancer Cell Line
Gene: Cacna1c (calcium channel, voltage-dependent, L type, alpha 1C subunit) Type: protein-coding Summary: Enables enzyme binding activity and voltage-gated calcium channel activity involved in cardiac muscle cell action potential. Involved in positive regulation of adenylate cyclase activity. Acts upst...
Does Knockout of Cic in Melanoma Cell Line causally result in protein/peptide accumulation?
0
1,839
Knockout
Cic
protein/peptide accumulation
Melanoma Cell Line
Gene: Cic (capicua transcriptional repressor) Type: protein-coding Summary: Enables chromatin binding activity. Involved in several processes, including learning or memory; negative regulation of DNA-templated transcription; and social behavior. Acts upstream of or within lung alveolus development and n...
Does Knockout of Cinp in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Cinp
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cinp (cyclin dependent kinase 2 interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, DNA replication, biological_process, cell division, ribosomal large subunit biogenesis, ribosome biogenesis; MF: molecular_function,...
Does Knockout of Ifna11 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Ifna11
protein/peptide accumulation
Microglial Cell Line
Gene: Ifna11 (interferon alpha 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell activation involved in immune response, T cell activation involved in immune response, adaptive immune response, defense response, defense response to virus, humoral immune response,...
Does Knockout of Tal1 in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Tal1
cell proliferation
Regulatory T cell
Gene: Tal1 (T cell acute lymphocytic leukemia 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, astrocyte fate commitment, basophil differentiation, cell differentiation, cell fate commitment, central nervous system neuron differentiation, definitive hemopo...
Does Knockout of Vat1 in Immortal mouse chromaffin cells causally result in cell viability?
1
2,469
Knockout
Vat1
cell viability
Immortal mouse chromaffin cells
Gene: Vat1 (vesicle amine transport 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intermembrane phospholipid transfer, negative regulation of mitochondrial fusion; MF: NADPH dehydrogenase (quinone) activity, oxidoreductase activity, phospholipid transfer activity, zi...
Does Knockout of Cd3d in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Cd3d
protein/peptide accumulation
Microglial Cell Line
Gene: Cd3d (CD3 antigen, delta polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell activation, adaptive immune response, cell surface receptor signaling pathway, immune system process, positive thymic T cell selection, protein-containing complex assembly; ...
Does Knockout of N4bp2l1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
N4bp2l1
cell proliferation
Mouse kidney carcinoma cell
Gene: N4bp2l1 (NEDD4 binding protein 2-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q3V2Q8 Entrez ID: 100637
Does Knockout of Txn1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,174
Knockout
Txn1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Txn1 (thioredoxin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell redox homeostasis, cellular detoxification of hydrogen peroxide, cellular homeostasis, negative regulation of protein export from nucleus, negative regulation of transcription by RNA polymeras...
Does Knockout of Rpl37 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Rpl37
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Rpl37 (ribosomal protein L37) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, positive regulation of signal transduction by p53 class mediator, translation, translation at postsynapse, translation at presynapse; MF: MDM2/MDM4 family protein ...
Does Knockout of Kmt2a in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Kmt2a
cell proliferation
Colonic Cancer Cell Line
Gene: Kmt2a (lysine (K)-specific methyltransferase 2A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T-helper 2 cell differentiation, anterior/posterior pattern specification, cellular response to transforming growth factor beta stimulus, chromatin organization, circadi...
Does Knockout of Tmem91 in Melanoma Cell Line causally result in cell proliferation?
0
1,838
Knockout
Tmem91
cell proliferation
Melanoma Cell Line
Gene: Tmem91 (transmembrane protein 91) Type: protein-coding Summary: No summary available. Gene Ontology: CC: intracellular membrane-bounded organelle, membrane Pathways: UniProt: Q8C581 Entrez ID: 320208
Does Knockout of Ubqln2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Ubqln2
cell proliferation
Mouse kidney carcinoma cell
Gene: Ubqln2 (ubiquilin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, autophagosome assembly, autophagy, negative regulation of G protein-coupled receptor internalization, negative regulation of clathrin-dependent endocytosis, positive regulation of ERA...
Does Knockout of Kcnk6 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Kcnk6
protein/peptide distribution
myoblast cell line
Gene: Kcnk6 (potassium inwardly-rectifying channel, subfamily K, member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport, negative regulation of systemic arterial blood pressure, positive regulation of NLR...
Does Knockout of Ighv1-73 in Embryonic Fibroblast Cell Line causally result in cell proliferation?
1
345
Knockout
Ighv1-73
cell proliferation
Embryonic Fibroblast Cell Line
Gene: Ighv1-73 (immunoglobulin heavy variable 1-73) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of 1700102P08Rik in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
1700102P08Rik
protein/peptide accumulation
Regulatory T cell
Gene: 1700102P08Rik (RIKEN cDNA 1700102P08 gene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, spermatogenesis Pathways: UniProt: Q9D9C7 Entrez ID: 112418
Does Knockout of Med12 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Med12
protein/peptide accumulation
Embryonic Cell Line
Gene: Med12 (mediator complex subunit 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Schwann cell development, Wnt signaling pathway, planar cell polarity pathway, axis elongation involved in somitogenesis, embryonic brain development, embryonic neurocranium morphoge...
Does Knockout of Rps6ka4 in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Rps6ka4
cell cycle progression
breast epithelium
Gene: Rps6ka4 (ribosomal protein S6 kinase, polypeptide 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: TORC1 signaling, chromatin remodeling, inflammatory response, interleukin-1-mediated signaling pathway, intracellular signal transduction, positive regulation of tra...
Does Knockout of Zfp462 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Zfp462
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Zfp462 (zinc finger protein 462) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, positive regulation of transcription by RNA polymerase II; MF: DNA binding, metal ion binding, zinc ion binding; CC: nucleoplasm, nucleus Pathways: ...
Does Knockout of Snx33 in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Snx33
cell cycle progression
breast epithelium
Gene: Snx33 (sorting nexin 33) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, cleavage furrow formation, endocytosis, endosomal transport, endosome organization, intracellular protein transport, macropinocytosis, mitotic cell cycle, mitotic cytokinesis, ne...
Does Knockout of Glis2 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,481
Knockout
Glis2
protein/peptide accumulation
Regulatory T cell
Gene: Glis2 (GLIS family zinc finger 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cell differentiation involved in kidney development, central nervous system development, hematopoietic stem cell homeostasis, kidney development, negative regulat...
Does Knockout of Cib1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Cib1
cell proliferation
Embryonic Stem Cell Line
Gene: Cib1 (calcium and integrin binding 1) Type: protein-coding Summary: Enables protein-membrane adaptor activity and transmembrane transporter binding activity. Involved in several processes, including negative regulation of megakaryocyte differentiation; regulation of intracellular signal transducti...
Does Knockout of Rbm6 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Rbm6
response to virus
Embryonic Fibroblast Cell Line
Gene: Rbm6 (RNA binding motif protein 6) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: S4R1W5, Q3ULB0, S4R1I5, S4R1D1, A0A0A6YWN4, A0A0A6YXE2, A0A0A6YY54 Entrez ID: 19654
Does Knockout of Gcat in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Gcat
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Gcat (glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-threonine catabolic process, L-threonine catabolic process to glycine, biological_process; MF: 5-aminolevulinate synthase activity, acyltr...
Does Knockout of Rps6kb1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,308
Knockout
Rps6kb1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Rps6kb1 (ribosomal protein S6 kinase, polypeptide 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G1/S transition of mitotic cell cycle, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, TOR signaling, TORC1 signaling, TORC2 signaling, apop...
Does Knockout of Gapdh in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Gapdh
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gapdh (glyceraldehyde-3-phosphate dehydrogenase) Type: protein-coding Summary: This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct funct...
Does Knockout of Zfp706 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Zfp706
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Zfp706 (zinc finger protein 706) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA-templated transcription, negative regulation of stem cell population maintenance, regulation of translation; MF: metal ion binding, molecular_function, zinc i...
Does Knockout of Sowaha in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Sowaha
cell proliferation
Mouse kidney carcinoma cell
Gene: Sowaha (sosondowah ankyrin repeat domain family member A) Type: protein-coding Summary: Is expressed in brain; liver lobe; and sensory organ. Orthologous to human SOWAHA (sosondowah ankyrin repeat domain family member A). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology:...
Does Knockout of Mrfap1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Mrfap1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Mrfap1 (Morf4 family associated protein 1) Type: protein-coding Summary: Predicted to enable identical protein binding activity. Predicted to be located in nucleoplasm. Is expressed in brain; genitourinary system; liver; lung; and spleen. Orthologous to several human genes including MRFAP1 (Morf4 ...
Does Knockout of Ccnc in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,398
Knockout
Ccnc
protein/peptide accumulation
Microglial Cell Line
Gene: Ccnc (cyclin C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G0 to G1 transition, negative regulation of Notch signaling pathway, negative regulation of triglyceride metabolic process, positive regulation of transcription by RNA polymerase II, protein ubiquitinat...
Does Knockout of Paf1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Paf1
protein/peptide accumulation
Embryonic Cell Line
Gene: Paf1 (Paf1, RNA polymerase II complex component) Type: protein-coding Summary: Enables chromatin binding activity. Involved in several processes, including cellular response to lipopolysaccharide; endodermal cell fate commitment; and negative regulation of transcription by RNA polymerase II. Part ...
Does Knockout of Cd2bp2 in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Cd2bp2
cell proliferation
Colonic Cancer Cell Line
Gene: Cd2bp2 (CD2 cytoplasmic tail binding protein 2) Type: protein-coding Summary: Predicted to enable ribonucleoprotein complex binding activity. Predicted to be involved in RNA splicing and mRNA processing. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Predicted to be part of...
Does Knockout of Gnal in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Gnal
cell cycle progression
breast epithelium
Gene: Gnal (guanine nucleotide binding protein, alpha stimulating, olfactory type) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenylate cyclase-ac...
Does Knockout of Tmem88 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Tmem88
response to virus
Microglial Cell Line
Gene: Tmem88 (transmembrane protein 88) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, negative regulation of canonical Wnt signaling pathway, protein localization to plasma membrane, protein stabilization; MF: PDZ domain binding, protein binding; ...
Does Knockout of Inca1 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Inca1
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Inca1 (inhibitor of CDK, cyclin A1 interacting protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic signaling pathway, negative regulation of cell population proliferation, negative regulation of fibroblast proliferation, positive regulation of apopt...
Does Knockout of Rgs3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Rgs3
cell proliferation
Mouse kidney carcinoma cell
Gene: Rgs3 (regulator of G-protein signaling 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, negative regulation of signal transduction; MF: GTPase activator activity; CC: cytoplasm, membrane, nucleus, plasma membrane ...
Does Knockout of Alkbh7 in myoblast cell line causally result in protein/peptide distribution?
0
1,679
Knockout
Alkbh7
protein/peptide distribution
myoblast cell line
Gene: Alkbh7 (alkB homolog 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, fatty acid metabolic process, oxidative RNA demethylation, programmed cell death, regulation of lipid storage, regulation of mitochondrial membrane permeability involved in ...
Does Knockout of Npy4r in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Npy4r
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Npy4r (neuropeptide Y receptor Y4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, neuropeptide signaling pathway, signal transduction; MF: G protein-coupled receptor activity, neuropeptide Y receptor activity, neuropept...
Does Knockout of Psapl1 in Melanoma Cell Line causally result in protein/peptide accumulation?
0
1,839
Knockout
Psapl1
protein/peptide accumulation
Melanoma Cell Line
Gene: Psapl1 (prosaposin-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, epithelial cell differentiation involved in prostate gland development, lipid metabolic process, prostate gland grow...
Does Knockout of Pcdhb5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Pcdhb5
cell proliferation
Mouse kidney carcinoma cell
Gene: Pcdhb5 (protocadherin beta 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules; MF: calcium ion binding, cell adhesion molecule binding; CC: membrane, plasma membrane Pathways: ...
Does Knockout of Sned1 in cardiac muscle cell line causally result in protein/peptide accumulation?
0
1,662
Knockout
Sned1
protein/peptide accumulation
cardiac muscle cell line
Gene: Sned1 (sushi, nidogen and EGF-like domains 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, cell-matrix adhesion; MF: Notch binding, calcium ion binding, molecular_function; CC: extracellular matrix, extracellular region Pathways: ...
Does Knockout of Irf1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Irf1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Irf1 (interferon regulatory factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CD8-positive, alpha-beta T cell differentiation, apoptotic process, canonical NF-kappaB signal transduction, cellular response to interferon-beta, cellular response to interleukin-...
Does Knockout of Ctdsp2 in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Ctdsp2
response to bacteria
renal medulla cell line
Gene: Ctdsp2 (CTD small phosphatase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of G1/S transition of mitotic cell cycle, regulation of transcription by RNA polymerase II; MF: RNA polymerase II CTD heptapeptide repeat phosphatase activity, hydro...
Does Knockout of Agpat1 in Embryonic Fibroblast Cell Line causally result in protein/peptide accumulation?
0
1,521
Knockout
Agpat1
protein/peptide accumulation
Embryonic Fibroblast Cell Line
Gene: Agpat1 (1-acylglycerol-3-phosphate O-acyltransferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CDP-diacylglycerol biosynthetic process, lipid metabolic process, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, positive regulation o...
Does Knockout of Bahd1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Bahd1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Bahd1 (bromo adjacent homology domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, heterochromatin formation, negative regulation of DNA-templated transcription; MF: chromatin binding, transcription cis-regulatory region bind...
Does Knockout of Mrpl40 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Mrpl40
cell proliferation
Mouse kidney carcinoma cell
Gene: Mrpl40 (mitochondrial ribosomal protein L40) Type: protein-coding Summary: No summary available. Gene Ontology: CC: mitochondrial inner membrane, mitochondrial large ribosomal subunit, mitochondrial ribosome, mitochondrion, nucleolus, ribonucleoprotein complex, ribosome Pathways:...
Does Knockout of Rps15a in small cell lung cancer causally result in cell proliferation?
1
1,714
Knockout
Rps15a
cell proliferation
small cell lung cancer
Gene: Rps15a (ribosomal protein S15A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, positive regulation of cell cycle, positive regulation of cell population proliferation, response to virus, ribosomal small subunit biogenesis, translation, tran...
Does Knockout of Tmprss11e in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Tmprss11e
protein/peptide accumulation
Embryonic Cell Line
Gene: Tmprss11e (transmembrane protease, serine 11e) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cognition, proteolysis; MF: hydrolase activity, peptidase activity, protein binding, serine-type endopeptidase activity, serine-type peptidase activity; CC: extracellular ...
Does Knockout of Ogfr in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,275
Knockout
Ogfr
cell proliferation
Colonic Cancer Cell Line
Gene: Ogfr (opioid growth factor receptor) Type: protein-coding Summary: No summary available. Gene Ontology: MF: opioid growth factor receptor activity, signaling receptor activity; CC: cytoplasm, membrane, nucleus Pathways: UniProt: Q99PG2 Entrez ID: 72075
Does Knockout of Rad51c in Lymphoma Cell Line causally result in response to chemicals?
0
1,539
Knockout
Rad51c
response to chemicals
Lymphoma Cell Line
Gene: Rad51c (RAD51 paralog C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, double-strand break repair via homologous recombination, female meiosis sister chromatid cohesion, male meiosis I, meiotic DNA recombinase as...
Does Knockout of Fcrl1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,268
Knockout
Fcrl1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Fcrl1 (Fc receptor-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: coreceptor activity, protein phosphatase binding, signaling adaptor activity; CC: cell surface, membrane, plasma membrane Pathways: UniProt: Q8R4Y0 Entrez ID: 22949...
Does Knockout of Zranb1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Zranb1
cell proliferation
Mouse kidney carcinoma cell
Gene: Zranb1 (zinc finger, RAN-binding domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, autophagosome assembly, cell migration, cytoskeleton organization, phosphatidylinositol phosphate biosynthetic process, positive regulation o...
Does Knockout of Ggps1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,261
Knockout
Ggps1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ggps1 (geranylgeranyl diphosphate synthase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: farnesyl diphosphate biosynthetic process, geranyl diphosphate biosynthetic process, geranylgeranyl diphosphate biosynthetic process, isoprenoid biosynthetic process, isopr...
Does Knockout of Smarcd1 in Colonic Cancer Cell Line causally result in tumorigenicity?
1
2,181
Knockout
Smarcd1
tumorigenicity
Colonic Cancer Cell Line
Gene: Smarcd1 (SWI/SNF related BAF chromatin remodeling complex subunit D1) Type: protein-coding Summary: Predicted to enable chromatin binding activity; signaling receptor binding activity; and transcription coregulator activity. Predicted to be involved in nucleosome disassembly; regulation of transcr...
Does Knockout of Cox6b2 in macrophage causally result in phagocytosis?
0
1,890
Knockout
Cox6b2
phagocytosis
macrophage
Gene: Cox6b2 (cytochrome c oxidase subunit 6B2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, oxidative phosphorylation; CC: membrane, mitochondrial crista, mitochondrial inner membrane, mitochondrion, respiratory chain complex IV Pathways: ...
Does Knockout of Atat1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,175
Knockout
Atat1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Atat1 (alpha tubulin acetyltransferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: alpha-tubulin acetylation, dentate gyrus development, microtubule cytoskeleton organization, neuron development, positive regulation of NLRP3 inflammasome complex assembly, reg...
Does Knockout of Stip1 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Stip1
protein/peptide accumulation
Mouse cell
Gene: Stip1 (stress-induced phosphoprotein 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: Hsp70 protein binding, Hsp90 protein binding, protein binding, protein-folding chaperone binding; CC: cytoplasm, cytosol, dynein axonemal particle, myelin sheath, nucleus, protei...
Does Knockout of Psmd11 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
83
Knockout
Psmd11
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Psmd11 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteasome assembly, stem cell differentiation, ubiquitin-dependent protein catabolic process; MF: protein binding, structural molecule activity; CC:...
Does Knockout of Prrt2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Prrt2
cell proliferation
Mouse kidney carcinoma cell
Gene: Prrt2 (proline-rich transmembrane protein 2) Type: protein-coding Summary: Enables syntaxin-1 binding activity. Involved in negative regulation of short-term synaptic potentiation; regulation of vesicle fusion; and synaptic vesicle fusion to presynaptic active zone membrane. Located in axon termin...
Does Knockout of Rabep2 in myoblast cell line causally result in protein/peptide distribution?
0
1,685
Knockout
Rabep2
protein/peptide distribution
myoblast cell line
Gene: Rabep2 (rabaptin, RAB GTPase binding effector protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, endocytosis, protein transport, regulation of cilium assembly, signal transduction; MF: GTPase activator activity, growth factor ac...
Does Knockout of Catsper3 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Catsper3
cell proliferation
Melanoma Cell Line
Gene: Catsper3 (cation channel, sperm associated 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion transmembrane transport, calcium ion transport, cell differentiation, establishment of localization in cell, flagellated sperm motility, monoatomic ion transmem...
Does Knockout of Gm5916 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Gm5916
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Gm5916 (predicted gene 5916) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: G5E8W5 Entrez ID: 546123
Does Knockout of Gstm3 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Gstm3
protein/peptide accumulation
Mouse cell
Gene: Gstm3 (glutathione S-transferase, mu 3) Type: protein-coding Summary: Predicted to enable several functions, including glutathione binding activity; glutathione transferase activity; and protein homodimerization activity. Acts upstream of or within cellular response to xenobiotic stimulus and resp...
Does Knockout of Ctxn3 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Ctxn3
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ctxn3 (cortexin 3) Type: protein-coding Summary: Predicted to be located in membrane. Is expressed in genitourinary system and otocyst. Orthologous to human CTXN3 (cortexin 3). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: CC: cellular_component, membrane Pa...
Does Knockout of Tmem268 in Melanoma Cell Line causally result in protein/peptide accumulation?
0
1,839
Knockout
Tmem268
protein/peptide accumulation
Melanoma Cell Line
Gene: Tmem268 (transmembrane protein 268) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane, plasma membrane Pathways: UniProt: Q8R239 Entrez ID: 230279
Does Knockout of Ears2 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Ears2
protein/peptide distribution
Microglial Cell Line
Gene: Ears2 (glutamyl-tRNA synthetase 2, mitochondrial) Type: protein-coding Summary: This gene encodes a putative member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is enco...
Does Knockout of Csf2ra in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Csf2ra
cell proliferation
Melanoma Cell Line
Gene: Csf2ra (colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway via JAK-STAT, cellular response to granulocyte macrophage colony-stimulating factor st...
Does Knockout of Synpo in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Synpo
cell proliferation
Mouse kidney carcinoma cell
Gene: Synpo (synaptopodin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cortical cytoskeleton organization, positive regulation of actin filament bundle assembly, postsynaptic modulation of chemical synaptic transmission, regulation of long-term neuronal synaptic plast...
Does Knockout of Pced1b in Melanoma Cell Line causally result in cell proliferation?
1
1,838
Knockout
Pced1b
cell proliferation
Melanoma Cell Line
Gene: Pced1b (PC-esterase domain containing 1B) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8BGX1 Entrez ID: 239647
Does Knockout of Nkg7 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Nkg7
phagocytosis
macrophage
Gene: Nkg7 (natural killer cell group 7 sequence) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CD4-positive, alpha-beta T cell activation, defense response to protozoan, granzyme-mediated programmed cell death signaling pathway, inflammatory response, killing of cells ...
Does Knockout of Lats2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Lats2
cell proliferation
Mouse kidney carcinoma cell
Gene: Lats2 (large tumor suppressor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G1/S transition of mitotic cell cycle, cell division, hippo signaling, hormone-mediated signaling pathway, inner cell mass cell fate commitment, inner cell mass cellular morphogenesis, ...
Does Knockout of Rap2b in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Rap2b
protein/peptide accumulation
Regulatory T cell
Gene: Rap2b (RAP2B, member of RAS oncogene family) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rap protein signal transduction, negative regulation of cell migration, platelet activation, platelet aggregation, regulation of protein tyrosine kinase activity, signal tra...
Does Knockout of Ptk2b in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,170
Knockout
Ptk2b
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ptk2b (PTK2 protein tyrosine kinase 2 beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, MAPK cascade, actin filament organization, adaptive immune response, angiogenesis, blood vessel endothelial cell migration, bone resorption, cell adhesion...
Does Knockout of Tldc2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,268
Knockout
Tldc2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Tldc2 (TBC/LysM associated domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of cellular response to oxidative stress, response to oxidative stress Pathways: UniProt: A2ACG1 Entrez ID: 383766
Does Knockout of Cfhr1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,260
Knockout
Cfhr1
cell proliferation
Mouse kidney carcinoma cell
Gene: Cfhr1 (complement factor H-related 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blood coagulation, complement activation; MF: complement component C3b binding, identical protein binding; CC: extracellular region, extracellular space, protein-containing complex...
Does Knockout of Serpinb9f in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Serpinb9f
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Serpinb9f (serine (or cysteine) peptidase inhibitor, clade B, member 9f) Type: protein-coding Summary: No summary available. Gene Ontology: BP: hematopoietic progenitor cell differentiation, immune response, negative regulation of apoptotic process, protection from natural killer cell med...
Does Knockout of Mrto4 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Mrto4
response to virus
Embryonic Fibroblast Cell Line
Gene: Mrto4 (mRNA turnover 4, ribosome maturation factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: nuclear-transcribed mRNA catabolic process, rRNA processing, ribosomal large subunit assembly, ribosomal large subunit biogenesis, ribosome biogenesis; CC: cytoplasm,...
Does Knockout of Gal3st2b in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Gal3st2b
response to virus
Embryonic Fibroblast Cell Line
Gene: Gal3st2b (galactose-3-O-sulfotransferase 2B) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q6XQH0 Entrez ID: 100041596
Does Knockout of Pfn2 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Pfn2
response to virus
Microglial Cell Line
Gene: Pfn2 (profilin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, modification of postsynaptic actin cytoskeleton, modulation of chemical synaptic transmission, negative regulation of actin filament polymerization, negative regulatio...
Does Knockout of Dynlrb1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Dynlrb1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Dynlrb1 (dynein light chain roadblock-type 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule-based movement, visual behavior; MF: dynein intermediate chain binding, identical protein binding, protein binding; CC: centrosome, cytoplasm, cytoplasmic dynei...
Does Knockout of Adrb1 in Embryonic Fibroblast Cell Line causally result in cell proliferation?
0
345
Knockout
Adrb1
cell proliferation
Embryonic Fibroblast Cell Line
Gene: Adrb1 (adrenergic receptor, beta 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, Rho protein signal transduction, adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenylate cyclase-activating...
Does Knockout of Ccdc18 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Ccdc18
cell proliferation
Colonic Cancer Cell Line
Gene: Ccdc18 (coiled-coil domain containing 18) Type: protein-coding Summary: Predicted to be located in centriolar satellite. Orthologous to human CCDC18 (coiled-coil domain containing 18). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: BP: biological_process, positive reg...
Does Knockout of Esco1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Esco1
protein/peptide accumulation
Embryonic Cell Line
Gene: Esco1 (establishment of sister chromatid cohesion N-acetyltransferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitotic sister chromatid cohesion, peptidyl-lysine acetylation, post-translational protein acetylation, regulation of DNA replication; MF: N-acet...