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string
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Does Knockout of Ubfd1 in myoblast cell line causally result in protein/peptide distribution?
0
1,685
Knockout
Ubfd1
protein/peptide distribution
myoblast cell line
Gene: Ubfd1 (ubiquitin family domain containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q78JW9 Entrez ID: 28018
Does Knockout of Lrrn4 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Lrrn4
protein/peptide accumulation
Embryonic Cell Line
Gene: Lrrn4 (leucine rich repeat neuronal 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: long-term memory, visual learning; CC: membrane, plasma membrane Pathways: UniProt: P59383 Entrez ID: 320974
Does Knockout of Htr2a in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Htr2a
cell proliferation
Colonic Cancer Cell Line
Gene: Htr2a (5-hydroxytryptamine (serotonin) receptor 2A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, G protein-coupled serotonin...
Does Knockout of Rps15a in macrophage causally result in phagocytosis?
0
1,890
Knockout
Rps15a
phagocytosis
macrophage
Gene: Rps15a (ribosomal protein S15A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoplasmic translation, positive regulation of cell cycle, positive regulation of cell population proliferation, response to virus, ribosomal small subunit biogenesis, translation, tran...
Does Knockout of Gls in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,272
Knockout
Gls
cell proliferation
Mouse kidney carcinoma cell
Gene: Gls (glutaminase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-glutamine catabolic process, chemical synaptic transmission, glutamate biosynthetic process, glutamine metabolic process, intracellular glutamate homeostasis, protein homotetramerization, regulation...
Does Knockout of Phlpp1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Phlpp1
cell proliferation
Mouse kidney carcinoma cell
Gene: Phlpp1 (PH domain and leucine rich repeat protein phosphatase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, entrainment of circadian clock, intracellular signal transduction, negative regulation of intracellular signal transduction, negative ...
Does Knockout of Plekhh3 in macrophage causally result in phagocytosis?
0
1,890
Knockout
Plekhh3
phagocytosis
macrophage
Gene: Plekhh3 (pleckstrin homology domain containing, family H (with MyTH4 domain) member 3) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8VCE9 Entrez ID: 217198
Does Knockout of Esf1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
84
Knockout
Esf1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Esf1 (ESF1 nucleolar pre-rRNA processing protein homolog) Type: protein-coding Summary: No summary available. Gene Ontology: BP: rRNA processing; CC: nucleolus, nucleoplasm, nucleus Pathways: UniProt: Q3V1V3 Entrez ID: 66580
Does Knockout of Cfap126 in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Cfap126
response to bacteria
renal medulla cell line
Gene: Cfap126 (cilia and flagella associated protein 126) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, cilium organization, flagellated sperm motility; CC: apical plasma membrane, axonemal B tubule inner sheath, axonemal microtubule, cell ...
Does Knockout of Tmem161b in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Tmem161b
cell proliferation
Embryonic Stem Cell Line
Gene: Tmem161b (transmembrane protein 161B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of cardiac muscle cell action potential, regulation of heart rate; CC: cellular_component, membrane, plasma membrane Pathways: UniProt: Q8C2L6 ...
Does Knockout of Tctn3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Tctn3
cell proliferation
Mouse kidney carcinoma cell
Gene: Tctn3 (tectonic family member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cell projection organization, cilium assembly, positive regulation of apoptotic process, smoothened signaling pathway; CC: membrane, nucleus Pathways: Anchor...
Does Knockout of Amigo2 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Amigo2
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Amigo2 (adhesion molecule with Ig like domain 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, cell adhesion, heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, homophilic cell adhesion via plasma membrane adhesion mole...
Does Knockout of Prss41 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,279
Knockout
Prss41
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Prss41 (serine protease 41) Type: protein-coding Summary: No summary available. Gene Ontology: MF: hydrolase activity, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity; CC: intracellular organelle, membrane, plasma membrane, side of membrane ...
Does Knockout of Fkbp1b in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Fkbp1b
cell proliferation
Mouse kidney carcinoma cell
Gene: Fkbp1b (FK506 binding protein 1b) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell proliferation, calcium-mediated signaling, establishment of localization in cell, insulin secretion, negative regulation of calcium-mediated signaling, negative regulation of he...
Does Knockout of Rbm12b2 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Rbm12b2
cell proliferation
Embryonic Stem Cell Line
Gene: Rbm12b2 (RNA binding motif protein 12 B2) Type: protein-coding Summary: Predicted to enable RNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Orthologous to human RBM12B (RNA bindi...
Does Knockout of Knl1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Knl1
cell proliferation
Mouse kidney carcinoma cell
Gene: Knl1 (kinetochore scaffold 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, attachment of spindle microtubules to kinetochore, cell division, chromosome segregation, establishment of localization in cell, head development, homologous chromosom...
Does Knockout of Krt19 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Krt19
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Krt19 (keratin 19) Type: protein-coding Summary: The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytok...
Does Knockout of Pdilt in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Pdilt
cell proliferation
Mouse kidney carcinoma cell
Gene: Pdilt (protein disulfide isomerase-like, testis expressed) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, germ cell migration, protein folding, spermatid development, spermatogenesis; MF: isomerase activity, protein binding, protein disulfide ...
Does Knockout of Speer3 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Speer3
response to chemicals
Pancreatic Cancer Cell Line
Gene: Speer3 (spermatogenesis associated glutamate (E)-rich protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9D4A3, W4VSP1 Entrez ID: 71026
Does Knockout of Gtpbp6 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Gtpbp6
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Gtpbp6 (GTP binding protein 6 (putative)) Type: protein-coding Summary: No summary available. Gene Ontology: MF: GTP binding, metal ion binding, molecular_function, nucleotide binding, ribosome binding Pathways: UniProt: Q3U6U5 Entrez ID: 107999
Does Knockout of Hnrnpab in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Hnrnpab
cell proliferation
Colonic Cancer Cell Line
Gene: Hnrnpab (heterogeneous nuclear ribonucleoprotein A/B) Type: protein-coding Summary: This gene encodes a protein with consensus RNA binding domains present in a number of other RNA binding proteins and a glycine-rich C-terminus. This gene overlaps in a tail-to-tail orientation the gene encoding ala...
Does Knockout of Serpina3a in macrophage causally result in phagocytosis?
0
1,889
Knockout
Serpina3a
phagocytosis
macrophage
Gene: Serpina3a (serine (or cysteine) peptidase inhibitor, clade A, member 3A) Type: protein-coding Summary: No summary available. Gene Ontology: MF: peptidase inhibitor activity, serine-type endopeptidase inhibitor activity; CC: extracellular region, extracellular space Pathways: ...
Does Knockout of Gm4894 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Gm4894
cell proliferation
Mouse kidney carcinoma cell
Gene: Gm4894 (predicted gene 4894) Type: ncRNA Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 235327
Does Knockout of Atp11b in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Atp11b
protein/peptide distribution
myoblast cell line
Gene: Atp11b (ATPase, class VI, type 11B) Type: protein-coding Summary: Predicted to enable ATPase-coupled intramembrane lipid transporter activity. Predicted to be involved in phospholipid translocation. Predicted to be located in early endosome membrane. Predicted to be part of phospholipid-translocat...
Does Knockout of Mpv17l in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,268
Knockout
Mpv17l
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Mpv17l (Mpv17 transgene, kidney disease mutant-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of hydrogen peroxide biosynthetic process, negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling p...
Does Knockout of Lct in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Lct
cell proliferation
Colonic Cancer Cell Line
Gene: Lct (lactase) Type: protein-coding Summary: Predicted to enable hydrolase activity, hydrolyzing O-glycosyl compounds; protein homodimerization activity; and transferase activity. Predicted to be involved in several processes, including disaccharide catabolic process; glycosylceramide catabolic pro...
Does Knockout of Vmn1r158 in Microglial Cell Line causally result in response to virus?
0
1,438
Knockout
Vmn1r158
response to virus
Microglial Cell Line
Gene: Vmn1r158 (vomeronasal 1 receptor 158) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, biological_process, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled recepto...
Does Knockout of Krt18 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Krt18
response to virus
Embryonic Fibroblast Cell Line
Gene: Krt18 (keratin 18) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi to plasma membrane protein transport, extrinsic apoptotic signaling pathway, hepatocyte apoptotic process, intermediate filament cytoskeleton organization, negative regulation of apoptotic proc...
Does Knockout of Grem1 in Embryonic Fibroblast Cell Line causally result in cell proliferation?
0
345
Knockout
Grem1
cell proliferation
Embryonic Fibroblast Cell Line
Gene: Grem1 (gremlin 1, DAN family BMP antagonist) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, animal organ morphogenesis, cardiac muscle cell differentiation, cardiac muscle cell myoblast differentiation, cell migration involved in sprouting angiogenesi...
Does Knockout of Mcm3ap in Cytotoxic T-lymphocyte (CD8+ T cells) causally result in cell proliferation?
1
2,412
Knockout
Mcm3ap
cell proliferation
Cytotoxic T-lymphocyte (CD8+ T cells)
Gene: Mcm3ap (minichromosome maintenance complex component 3 associated protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: immune system process, mRNA export from nucleus, mRNA transport, nucleosome organization, poly(A)+ mRNA export from nucleus, protein transport,...
Does Knockout of Ikbip in macrophage causally result in response to bacteria?
0
2,211
Knockout
Ikbip
response to bacteria
macrophage
Gene: Ikbip (IKBKB interacting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: response to interleukin-1, response to lipopolysaccharide, response to tumor necrosis factor; MF: molecular_function, protein binding; CC: endoplasmic reticulum, endoplasmic reticulum ...
Does Knockout of Zfp30 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Zfp30
protein/peptide accumulation
Embryonic Cell Line
Gene: Zfp30 (zinc finger protein 30) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA po...
Does Knockout of Htr7 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Htr7
cell proliferation
Mouse kidney carcinoma cell
Gene: Htr7 (5-hydroxytryptamine (serotonin) receptor 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, G protein-coupled serotonin r...
Does Knockout of Spata21 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Spata21
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Spata21 (spermatogenesis associated 21) Type: protein-coding Summary: No summary available. Gene Ontology: MF: calcium ion binding, metal ion binding, molecular_function Pathways: UniProt: Q8BHW6 Entrez ID: 329972
Does Knockout of Ncr1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Ncr1
cell proliferation
Mouse kidney carcinoma cell
Gene: Ncr1 (natural cytotoxicity triggering receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to virus, detection of virus, immune response-regulating signaling pathway; CC: cell surface, membrane, plasma membrane Pathways: Natural kill...
Does Knockout of Mrpl30 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Mrpl30
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Mrpl30 (mitochondrial ribosomal protein L30) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial translation, translation; MF: molecular_function, structural constituent of ribosome; CC: large ribosomal subunit, mitochondrial inner membrane, mitochondrial ...
Does Knockout of Dctn3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,267
Knockout
Dctn3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Dctn3 (dynactin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, cytoskeleton-dependent cytokinesis, microtubule-based process; CC: centrosome, chromosome, chromosome, centromeric region, cleavage furrow, cytoplasm, cytoskeleton, cytosol, dynactin c...
Does Knockout of Kyat3 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Kyat3
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Kyat3 (kynurenine aminotransferase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 2-oxoglutarate metabolic process, L-kynurenine catabolic process, amino acid metabolic process, kynurenine metabolic process; MF: cysteine-S-conjugate beta-lyase activity, kynureni...
Does Knockout of Idh3b in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Idh3b
protein/peptide distribution
Microglial Cell Line
Gene: Idh3b (isocitrate dehydrogenase 3 (NAD+) beta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: isocitrate metabolic process, tricarboxylic acid cycle; MF: NAD binding, magnesium ion binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP a...
Does Knockout of Sparc in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Sparc
protein/peptide distribution
Microglial Cell Line
Gene: Sparc (secreted acidic cysteine rich glycoprotein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bone development, cellular response to growth factor stimulus, lung development, negative regulation of angiogenesis, negative regulation of endothelial cell prolifera...
Does Knockout of Tmco4 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Tmco4
cell proliferation
Embryonic Stem Cell Line
Gene: Tmco4 (transmembrane and coiled-coil domains 4) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q91WU4 Entrez ID: 77056
Does Knockout of Mrm1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Mrm1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Mrm1 (mitochondrial rRNA methyltransferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA processing, methylation, rRNA 2'-O-methylation, rRNA methylation, rRNA modification, rRNA processing; MF: RNA binding, RNA methyltransferase activity, methyltransferase...
Does Knockout of Ccdc13 in Melanoma Cell Line causally result in cell proliferation?
0
1,281
Knockout
Ccdc13
cell proliferation
Melanoma Cell Line
Gene: Ccdc13 (coiled-coil domain containing 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, axoneme assembly, cell projection organization, cytoplasmic microtubule organization, non-motile cilium assembly; MF: microtubule binding, molecular_functi...
Does Knockout of Btbd16 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Btbd16
protein/peptide accumulation
Embryonic Cell Line
Gene: Btbd16 (BTB domain containing 16) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: E9Q173 Entrez ID: 330660
Does Knockout of Zswim3 in Melanoma Cell Line causally result in cell proliferation?
0
1,838
Knockout
Zswim3
cell proliferation
Melanoma Cell Line
Gene: Zswim3 (zinc finger SWIM-type containing 3) Type: protein-coding Summary: Predicted to enable zinc ion binding activity. Orthologous to human ZSWIM3 (zinc finger SWIM-type containing 3). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: MF: metal ion binding, molecular_f...
Does Knockout of Il27ra in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Il27ra
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Il27ra (interleukin 27 receptor, alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway, defense response to Gram-positive bacterium, interleukin-27-mediated signaling pathway, negative regulation of T cell extravasation, nega...
Does Knockout of H2-Aa in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
H2-Aa
response to virus
Neuroblastoma Cell Line
Gene: H2-Aa (histocompatibility 2, class II antigen A, alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, antigen processing and presentation, antigen processing and presentation of exogenous peptide antigen via MHC class II, antigen processi...
Does Knockout of Uqcc1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Uqcc1
cell proliferation
Mouse kidney carcinoma cell
Gene: Uqcc1 (ubiquinol-cytochrome c reductase complex assembly factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial respiratory chain complex III assembly; CC: cytoplasmic vesicle, membrane, mitochondrial inner membrane, mitochondrion Pathways:...
Does Knockout of Il13ra2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Il13ra2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Il13ra2 (interleukin 13 receptor, alpha 2) Type: protein-coding Summary: This gene encodes a receptor protein that binds to interleukin 13 (IL-13) with very high affinity. The encoded protein acts as a decoy receptor, and does not elicit any signal upon the binding of IL-13. Mice lacking the encod...
Does Knockout of Crlf2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Crlf2
cell proliferation
Mouse kidney carcinoma cell
Gene: Crlf2 (cytokine receptor-like factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytokine-mediated signaling pathway, inflammatory response, positive regulation of cell population proliferation, positive regulation of interleukin-5 production, positive regula...
Does Knockout of Spata19 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Spata19
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Spata19 (spermatogenesis associated 19) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, sperm mitochondrion organization, spermatogenesis; CC: cell projection, cilium, membrane, mitochondrial outer membrane, mitochondrion, motile cilium, sperm ...
Does Knockout of Phf10 in Lung Cancer Cell Line causally result in tumorigenicity?
1
1,781
Knockout
Phf10
tumorigenicity
Lung Cancer Cell Line
Gene: Phf10 (PHD finger protein 10) Type: protein-coding Summary: Predicted to enable chromatin binding activity; histone acetyltransferase activity; and transcription coregulator activity. Involved in nervous system development. Part of npBAF complex. Is expressed in several structures, including centr...
Does Knockout of Gadl1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
1,565
Knockout
Gadl1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Gadl1 (glutamate decarboxylase-like 1) Type: protein-coding Summary: Predicted to enable carboxy-lyase activity. Predicted to be involved in carboxylic acid metabolic process. Predicted to be active in cytoplasm. Orthologous to human GADL1 (glutamate decarboxylase like 1). [provided by Alliance of...
Does Knockout of Mtpap in Microglial Cell Line causally result in response to virus?
0
1,439
Knockout
Mtpap
response to virus
Microglial Cell Line
Gene: Mtpap (mitochondrial poly(A) polymerase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA 3'-end processing, RNA metabolic process, histone mRNA catabolic process, mRNA processing, mitochondrial RNA 3'-end processing, mitochondrial mRNA polyadenylation; MF: ATP b...
Does Knockout of Prpf6 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
1
1,663
Knockout
Prpf6
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Prpf6 (pre-mRNA splicing factor 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA localization, RNA processing, RNA splicing, mRNA processing, mRNA splicing, via spliceosome, positive regulation of transcription by RNA polymerase II, spliceosomal tri-snRNP comp...
Does Knockout of Bok in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,259
Knockout
Bok
cell proliferation
Mouse kidney carcinoma cell
Gene: Bok (BCL2-related ovarian killer) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cellular component disassembly involved in execution phase of apoptosis, extrinsic apoptotic signaling pathway in absence of ligand, intrinsic apoptotic signaling pa...
Does Knockout of Fnta in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Fnta
protein/peptide distribution
myoblast cell line
Gene: Fnta (farnesyltransferase, CAAX box, alpha) Type: protein-coding Summary: No summary available. Gene Ontology: BP: enzyme-linked receptor protein signaling pathway, negative regulation of apoptotic process, nuclear envelope organization, peptide pheromone maturation, positive regulation o...
Does Knockout of Lrrc10 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Lrrc10
cell proliferation
Melanoma Cell Line
Gene: Lrrc10 (leucine rich repeat containing 10) Type: protein-coding Summary: Enables actin binding activity and alpha-actinin binding activity. Acts upstream of or within cardiac muscle cell development. Located in several cellular components, including cytoskeleton; mitochondrion; and sarcomere. Is e...
Does Knockout of Psg26 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Psg26
response to virus
Microglial Cell Line
Gene: Psg26 (pregnancy-specific beta-1-glycoprotein 26) Type: protein-coding Summary: Predicted to be involved in T cell activation and immune response. Predicted to be located in apical plasma membrane and cytosol. Predicted to be active in external side of plasma membrane. Orthologous to human CEACAM2...
Does Knockout of Amn1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,279
Knockout
Amn1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Amn1 (antagonist of mitotic exit network 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, cobalamin transport, vesicle-mediated transport; MF: cargo receptor activity, molecular_function; CC:...
Does Knockout of Dnm1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Dnm1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Dnm1 (dynamin 1) Type: protein-coding Summary: This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein is a GTPase which is required for membrane recycling, including vesicle endocytosis in neurons. It may also be involved in cellular fission via associatio...
Does Knockout of Fastkd3 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Fastkd3
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Fastkd3 (FAST kinase domains 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial RNA processing, mitochondrial cytochrome c oxidase assembly, positive regulation of mitochondrial translation, regulation of mitochondrial mRNA stability; CC: mitochondrial...
Does Knockout of Pde7a in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Pde7a
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Pde7a (phosphodiesterase 7A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cAMP catabolic process, negative regulation of cAMP/PKA signal transduction, signal transduction; MF: 3',5'-cyclic-AMP phosphodiesterase activity, 3',5'-cyclic-GMP phosphodiesterase activit...
Does Knockout of Ccdc90b in Melanoma Cell Line causally result in protein/peptide accumulation?
0
1,839
Knockout
Ccdc90b
protein/peptide accumulation
Melanoma Cell Line
Gene: Ccdc90b (coiled-coil domain containing 90B) Type: protein-coding Summary: No summary available. Gene Ontology: CC: membrane, mitochondrial membrane, mitochondrion Pathways: UniProt: Q8C3X2 Entrez ID: 66365
Does Knockout of Mlf1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Mlf1
cell proliferation
Mouse kidney carcinoma cell
Gene: Mlf1 (myeloid leukemia factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, cell differentiation, myeloid progenitor cell differentiation, regulation of DNA-templated transcription, regulation of cell cycle G1/S phase transition, re...
Does Knockout of Pfkfb1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Pfkfb1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Pfkfb1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate phosphorylation, fructose 2,6-bisphosphate metabolic process, fructose metabolic process, gluconeogenesis, glycolytic process, negative regula...
Does Knockout of Cwc22 in myoblast cell line causally result in protein/peptide distribution?
0
1,680
Knockout
Cwc22
protein/peptide distribution
myoblast cell line
Gene: Cwc22 (CWC22 spliceosome-associated protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, mRNA splicing, via spliceosome; MF: RNA binding; CC: U2-type catalytic step 1 spliceosome, U2-type catalytic step 2 spliceosome, U2-type preca...
Does Knockout of Cebpe in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
1,664
Knockout
Cebpe
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Cebpe (CCAAT/enhancer binding protein epsilon) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, cellular response to lipopolysaccharide, granulocyte differentiation, macrophage differentiation, myeloid cell differentiation, phagocytosis, ...
Does Knockout of Gpr143 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Gpr143
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gpr143 (G protein-coupled receptor 143) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, melanosome localization, melanosome organization, melanosome transport, neuropeptide signaling pathway, phospholipase C-activating G...
Does Knockout of Nell1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Nell1
cell proliferation
Mouse kidney carcinoma cell
Gene: Nell1 (NEL-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, negative regulation of osteoblast proliferation, negative regulation of protein catabolic process, positive regulation of apoptotic process, positive regulation of bone minerali...
Does Knockout of Arhgef39 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
1,565
Knockout
Arhgef39
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Arhgef39 (Rho guanine nucleotide exchange factor 39) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of cell migration; CC: membrane, plasma membrane Pathways: Cell death signalling via NRAGE, NRIF and NADE, Death Receptor Signaling, G a...
Does Knockout of Tulp2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,172
Knockout
Tulp2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Tulp2 (TUB like protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein localization to cilium; MF: phosphoric diester hydrolase activity, protein-containing complex binding; CC: cilium, cytoplasm, extracellular region Pathways: UniProt...
Does Knockout of Cmss1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Cmss1
cell proliferation
Embryonic Stem Cell Line
Gene: Cmss1 (cms small ribosomal subunit 1) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9CZT6 Entrez ID: 66497
Does Knockout of Zfp386 in cardiac muscle cell line causally result in protein/peptide accumulation?
0
1,662
Knockout
Zfp386
protein/peptide accumulation
cardiac muscle cell line
Gene: Zfp386 (zinc finger protein 386 (Kruppel-like)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, D...
Does Knockout of Itga2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
165
Knockout
Itga2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Itga2 (integrin alpha 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, cell adhesion mediated by integrin, cell-cell adhesion, cell-matrix adhesion, cell-substrate adhesion, cellular response to estradiol stimulus, cellular response to mechanical st...
Does Knockout of Gpc5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,260
Knockout
Gpc5
cell proliferation
Mouse kidney carcinoma cell
Gene: Gpc5 (glypican 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell migration, positive regulation of canonical Wnt signaling pathway, regulation of protein localization to membrane, regulation of signal transduction; CC: Golgi lumen, cell surface, extracellular ...
Does Knockout of Mug2 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Mug2
cell cycle progression
breast epithelium
Gene: Mug2 (murinoglobulin 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: endopeptidase inhibitor activity, peptidase inhibitor activity, protease binding, serine-type endopeptidase inhibitor activity; CC: extracellular region, extracellular space Pathways: ...
Does Knockout of Pros1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Pros1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Pros1 (protein S (alpha)) Type: protein-coding Summary: This gene encodes a vitamin K-dependent protein with key roles in multiple biological processes including coagulation, apoptosis and vasculogenesis. The encoded protein undergoes proteolytic processing to generate a mature protein which is se...
Does Knockout of Tmem70 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,398
Knockout
Tmem70
protein/peptide accumulation
Microglial Cell Line
Gene: Tmem70 (transmembrane protein 70) Type: protein-coding Summary: Predicted to enable mitochondrial proton-transporting ATP synthase complex binding activity. Involved in mitochondrial proton-transporting ATP synthase complex assembly. Located in mitochondrion. Is expressed in several structures, in...
Does Knockout of Bmpr2 in Pancreatic Cell Line causally result in protein/peptide accumulation?
0
2,197
Knockout
Bmpr2
protein/peptide accumulation
Pancreatic Cell Line
Gene: Bmpr2 (bone morphogenetic protein receptor type 2) Type: protein-coding Summary: This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type II receptor that binds extracellular BMPs and forms a complex of two type ...
Does Knockout of Elavl3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Elavl3
cell proliferation
Mouse kidney carcinoma cell
Gene: Elavl3 (ELAV like RNA binding protein 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, nervous system development; MF: RNA binding, mRNA 3'-UTR AU-rich region binding, nucleic acid binding Pathways: UniProt: Q60900 ...
Does Knockout of Ccdc50 in Melanoma Cell Line causally result in cell proliferation?
0
1,281
Knockout
Ccdc50
cell proliferation
Melanoma Cell Line
Gene: Ccdc50 (coiled-coil domain containing 50) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ubiquitin protein ligase binding; CC: ciliary basal body, cytoplasm, cytosol, microtubule cytoskeleton Pathways: UniProt: Q810U5 Entrez ID: 67501
Does Knockout of Usf2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Usf2
cell proliferation
Colonic Cancer Cell Line
Gene: Usf2 (upstream transcription factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to glucose stimulus, glucose mediated signaling pathway, lactation, lipid homeostasis, positive regulation of DNA-templated transcription, positive regulation of...
Does Knockout of Ermap in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,275
Knockout
Ermap
cell proliferation
Colonic Cancer Cell Line
Gene: Ermap (erythroblast membrane-associated protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell receptor signaling pathway, regulation of cytokine production; CC: Golgi apparatus, cytoplasm, cytoplasmic vesicle, cytosol, external side of plasma membrane, mem...
Does Knockout of Phf11d in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Phf11d
response to virus
Microglial Cell Line
Gene: Phf11d (PHD finger protein 11D) Type: protein-coding Summary: No summary available. Gene Ontology: MF: metal ion binding, molecular_function, zinc ion binding; CC: nuclear membrane, nucleoplasm, nucleus Pathways: UniProt: A6H5X4 Entrez ID: 219132
Does Knockout of Eif4g2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Eif4g2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Eif4g2 (eukaryotic translation initiation factor 4, gamma 2) Type: protein-coding Summary: Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits:...
Does Knockout of Mylk2 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Mylk2
cell proliferation
Embryonic Stem Cell Line
Gene: Mylk2 (myosin, light polypeptide kinase 2, skeletal muscle) Type: protein-coding Summary: Predicted to enable myosin light chain binding activity and myosin light chain kinase activity. Involved in skeletal muscle satellite cell differentiation. Acts upstream of or within neuromuscular synaptic tr...
Does Knockout of Mta2 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,177
Knockout
Mta2
tumorigenicity
Colonic Cancer Cell Line
Gene: Mta2 (metastasis-associated gene family, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin remodeling, chromosome organization, genomic imprinting, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA poly...
Does Knockout of Tacr3 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Tacr3
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Tacr3 (tachykinin receptor 3) Type: protein-coding Summary: This gene belongs to a family of genes that function as receptors for tachykinins. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the rec...
Does Knockout of Mir125b-1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Mir125b-1
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Mir125b-1 (microRNA 125b-1) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polyme...
Does Knockout of Zfp629 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Zfp629
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfp629 (zinc finger protein 629) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, metal ion binding, zinc ion binding; CC: nucleus Pathways: UniProt: Q6A085 Entrez ID: 320683
Does Knockout of Caap1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Caap1
protein/peptide accumulation
Embryonic Cell Line
Gene: Caap1 (caspase activity and apoptosis inhibitor 1) Type: protein-coding Summary: Predicted to be involved in negative regulation of apoptotic process. Orthologous to human CAAP1 (caspase activity and apoptosis inhibitor 1). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontolog...
Does Knockout of Secisbp2l in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Secisbp2l
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Secisbp2l (SECIS binding protein 2-like) Type: protein-coding Summary: No summary available. Gene Ontology: MF: mRNA 3'-UTR binding, ribonucleoprotein complex binding, selenocysteine insertion sequence binding; CC: mitochondrion, ribonucleoprotein complex Pathways: UniP...
Does Knockout of Gpr132 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Gpr132
cell proliferation
Mouse kidney carcinoma cell
Gene: Gpr132 (G protein-coupled receptor 132) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, G1/S transition of mitotic cell cycle, negative regulation of G2/M transition of mitotic cell cycle, signal transduction; MF: G prot...
Does Knockout of Slc25a20 in macrophage causally result in phagocytosis?
0
1,890
Knockout
Slc25a20
phagocytosis
macrophage
Gene: Slc25a20 (solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20) Type: protein-coding Summary: Predicted to enable O-acyl-L-carnitine transmembrane transporter activity and carnitine transmembrane transporter activity. Involved in carnitine shuttle. Acts upstream ...
Does Knockout of Card10 in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Card10
response to bacteria
renal medulla cell line
Gene: Card10 (caspase recruitment domain family, member 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: activation of NF-kappaB-inducing kinase activity, negative regulation of cell migration involved in sprouting angiogenesis, positive regulation of canonical NF-kapp...
Does Knockout of Polr3b in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Polr3b
cell proliferation
Colonic Cancer Cell Line
Gene: Polr3b (polymerase (RNA) III (DNA directed) polypeptide B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, defense response to virus, immune system process, innate immune response, positive regulation of innate immune response, positive ...
Does Knockout of Cdsn in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,263
Knockout
Cdsn
cell proliferation
Colonic Cancer Cell Line
Gene: Cdsn (corneodesmosin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: amyloid fibril formation, cell-cell adhesion, corneocyte desquamation, negative regulation of cornification, skin morphogenesis; MF: protein homodimerization activity; CC: cornified envelope, desm...
Does Knockout of Klra8 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Klra8
cell proliferation
Mouse kidney carcinoma cell
Gene: Klra8 (killer cell lectin-like receptor, subfamily A, member 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, response to virus; MF: carbohydrate binding, protein binding, signaling receptor activity; CC: cell surface, membrane, plasma membrane ...
Does Knockout of Rbmy in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Rbmy
response to virus
Embryonic Fibroblast Cell Line
Gene: Rbmy (RNA binding motif protein, Y chromosome) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, hematopoietic progenitor cell differentiation, mRNA processing, positive regulation of mRNA splicing, via spliceosome; MF: RNA binding, identical protein bin...