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Does Knockout of Ocstamp in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,277
Knockout
Ocstamp
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ocstamp (osteoclast stimulatory transmembrane protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cellular response to estrogen stimulus, cellular response to tumor necrosis factor, multinuclear osteoclast differentiation, positive regulat...
Does Knockout of Onecut1 in cardiac muscle cell line causally result in protein/peptide accumulation?
0
1,662
Knockout
Onecut1
protein/peptide accumulation
cardiac muscle cell line
Gene: Onecut1 (one cut domain, family member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, Notch signaling pathway, anatomical structure morphogenesis, cell fate commitment, cilium assembly, endocrine pancreas development, endoderm development...
Does Knockout of Mir3113 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Mir3113
cell cycle progression
breast epithelium
Gene: Mir3113 (microRNA 3113) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Vps26a in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Vps26a
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Vps26a (VPS26 retromer complex component A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endocytic recycling, intracellular protein transport, protein transport, retrograde transport, endosome to Golgi; CC: cytoplasm, cytosol, early endosome, endosome, endosome m...
Does Knockout of Usp1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Usp1
cell proliferation
Mouse kidney carcinoma cell
Gene: Usp1 (ubiquitin specific peptidase 1) Type: protein-coding Summary: This gene encodes a member of the ubiquitin-specific peptidase family. The encoded protein acts as a catalytic subunit in a heterodimeric deubiquitinating enzyme complex that deubiquitinates Fanconi anemia, complementation group D...
Does Knockout of Zfp90 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
167
Knockout
Zfp90
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Zfp90 (zinc finger protein 90) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of DNA binding, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, positive regulation of DNA-templated tra...
Does Knockout of Miox in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Miox
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Miox (myo-inositol oxygenase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: inositol catabolic process; MF: NADP binding, alcohol dehydrogenase (NADP+) activity, ferric iron binding, inositol oxygenase activity, iron ion binding, metal ion binding, oxidoreductase ...
Does Knockout of Ankrd49 in Embryonic Fibroblast Cell Line causally result in cell proliferation?
1
345
Knockout
Ankrd49
cell proliferation
Embryonic Fibroblast Cell Line
Gene: Ankrd49 (ankyrin repeat domain 49) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, positive regulation of DNA-templated transcription, spermatogenesis Pathways: UniProt: Q8VE42 Entrez ID: 56503
Does Knockout of B3gnt7 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
B3gnt7
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: B3gnt7 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: keratan sulfate proteoglycan biosynthetic process, poly-N-acetyllactosamine biosynthetic process, protein O-linked glycosylation, protein glycosyla...
Does Knockout of D5Ertd579e in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
D5Ertd579e
protein/peptide accumulation
Embryonic Cell Line
Gene: D5Ertd579e (DNA segment, Chr 5, ERATO Doi 579, expressed) Type: protein-coding Summary: Predicted to enable ATP binding activity. Orthologous to human KIAA0232 (KIAA0232). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: MF: ATP binding, molecular_function, nucleotide b...
Does Knockout of Vmn1r80 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Vmn1r80
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Vmn1r80 (vomeronasal 1 receptor 80) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromone ...
Does Knockout of Zfand1 in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Zfand1
cell proliferation
Melanoma Cell Line
Gene: Zfand1 (zinc finger, AN1-type domain 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to arsenite ion, positive regulation of intracellular protein transport, stress granule disassembly; MF: metal ion binding, proteasome binding, zinc ion binding...
Does Knockout of Stat2 in Melanoma Cell Line causally result in cell proliferation?
0
1,281
Knockout
Stat2
cell proliferation
Melanoma Cell Line
Gene: Stat2 (signal transducer and activator of transcription 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway via JAK-STAT, defense response, defense response to virus, negative regulation of type I interferon-mediated signaling ...
Does Knockout of Crnn in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Crnn
protein/peptide accumulation
Regulatory T cell
Gene: Crnn (cornulin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell-cell adhesion, cellular response to cytokine stimulus, positive regulation of cell cycle G1/S phase transition, positive regulation of keratinocyte proliferation, regulation of gene expression, reg...
Does Knockout of Zfp672 in Microglial Cell Line causally result in response to virus?
0
1,439
Knockout
Zfp672
response to virus
Microglial Cell Line
Gene: Zfp672 (zinc finger protein 672) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II transcription regulatory regi...
Does Knockout of Kat5 in Lymphoma Cell Line causally result in response to chemicals?
0
1,557
Knockout
Kat5
response to chemicals
Lymphoma Cell Line
Gene: Kat5 (K(lysine) acetyltransferase 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA damage response, signal transduction by p53 class mediator, DNA double-strand break processing, DNA repair, DNA repair-dependent chromatin remodeling, aggre...
Does Knockout of Rab5c in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Rab5c
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Rab5c (RAB5C, member RAS oncogene family) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endocytosis, endosomal transport, endosome organization, intracellular protein transport, plasma membrane to endosome transport, protein transport, regulation of endocytosis; M...
Does Knockout of Cenph in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Cenph
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Cenph (centromere protein H) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromosome segregation, kinetochore assembly, kinetochore organization, mitotic cell cycle, mitotic spindle organization; MF: kinetochore binding, protein binding; CC: chromosome, chromosom...
Does Knockout of Nanog in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Nanog
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Nanog (Nanog homeobox) Type: protein-coding Summary: The protein encoded by this gene is a DNA binding homeobox transcription factor involved in embryonic stem (ES) cell proliferation, renewal, and pluripotency. The encoded protein can block ES cell differentiation and can also autorepress its own...
Does Knockout of Grb14 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Grb14
protein/peptide accumulation
Mouse cell
Gene: Grb14 (growth factor receptor bound protein 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to insulin stimulus, insulin receptor signaling pathway, negative regulation of insulin receptor signaling pathway, negative regulation of meiotic cell ...
Does Knockout of Fbxo47 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Fbxo47
cell proliferation
Regulatory T cell
Gene: Fbxo47 (F-box protein 47) Type: protein-coding Summary: Orthologous to human FBXO47 (F-box protein 47). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: Pathways: UniProt: A2A6H3 Entrez ID: 72973
Does Knockout of Azin2 in myoblast cell line causally result in protein/peptide distribution?
0
1,680
Knockout
Azin2
protein/peptide distribution
myoblast cell line
Gene: Azin2 (antizyme inhibitor 2) Type: protein-coding Summary: The protein encoded by this gene belongs to the antizyme inhibitor family, which plays a role in cell growth and proliferation by maintaining polyamine homeostasis within the cell. Antizyme inhibitors are homologs of ornithine decarboxylas...
Does Knockout of Hsfy2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Hsfy2
cell proliferation
Mouse kidney carcinoma cell
Gene: Hsfy2 (heat shock transcription factor, Y-linked 2) Type: protein-coding Summary: Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be located in cytosol and nucleoplasm. Orthologous to several human genes including HSFY2 (heat shock transcription factor Y-li...
Does Knockout of Plekhb2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Plekhb2
cell proliferation
Mouse kidney carcinoma cell
Gene: Plekhb2 (pleckstrin homology domain containing, family B (evectins) member 2) Type: protein-coding Summary: No summary available. Gene Ontology: CC: endosome, membrane, recycling endosome membrane Pathways: UniProt: Q9QZC7 Entrez ID: 226971
Does Knockout of Slc17a8 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Slc17a8
phagocytosis
macrophage
Gene: Slc17a8 (solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-glutamate import, L-glutamate transmembrane transport, chloride transmembrane transport, chloride transport, cochlea d...
Does Knockout of Tap1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in cell proliferation?
1
2,141
Knockout
Tap1
cell proliferation
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Tap1 (transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)) Type: protein-coding Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular...
Does Knockout of Cst8 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Cst8
cell proliferation
Regulatory T cell
Gene: Cst8 (cystatin 8 (cystatin-related epididymal spermatogenic)) Type: protein-coding Summary: No summary available. Gene Ontology: MF: cysteine-type endopeptidase inhibitor activity, peptidase inhibitor activity; CC: cell surface, cytoplasm, extracellular region Pathways: ...
Does Knockout of Klrb1f in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Klrb1f
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Klrb1f (killer cell lectin-like receptor subfamily B member 1F) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carbohydrate binding, protein binding, signaling receptor activity; CC: cell surface, membrane, plasma membrane Pathways: Malaria - Mus musculus ...
Does Knockout of Grwd1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Grwd1
cell proliferation
Mouse kidney carcinoma cell
Gene: Grwd1 (glutamate-rich WD repeat containing 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA replication, nucleosome assembly, nucleosome disassembly, ribosome biogenesis; MF: DNA replication origin binding, chromatin binding, histone binding; CC: chromosome, c...
Does Knockout of Pim1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Pim1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Pim1 (proviral integration site 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, cellular detoxification, cellular response to amino acid starvation, cellular response to nutrient levels, cellular response to type II interferon, cytolysis in ano...
Does Knockout of Myh11 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Myh11
cell proliferation
Mouse kidney carcinoma cell
Gene: Myh11 (myosin, heavy polypeptide 11, smooth muscle) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actomyosin structure organization, cardiac muscle cell development, elastic fiber assembly, skeletal muscle myosin thick filament assembly, smooth muscle contraction;...
Does Knockout of Tvp23b in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Tvp23b
cell proliferation
Mouse kidney carcinoma cell
Gene: Tvp23b (trans-golgi network vesicle protein 23B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein secretion, vesicle-mediated transport; CC: Golgi membrane, membrane Pathways: UniProt: Q9D8T4 Entrez ID: 67510
Does Knockout of Pgm5 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Pgm5
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Pgm5 (phosphoglucomutase 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate metabolic process, cell adhesion, myofibril assembly, striated muscle tissue development; MF: magnesium ion binding, phosphoglucomutase activity, protein binding; CC: Z disc, ad...
Does Knockout of Grid1 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Grid1
protein/peptide accumulation
Regulatory T cell
Gene: Grid1 (glutamate receptor, ionotropic, delta 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ionotropic glutamate receptor signaling pathway, modulation of chemical synaptic transmission, monoatomic ion transmembrane transport, monoatomic ion transport, negative ...
Does Knockout of Slc10a6 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Slc10a6
cell proliferation
Mouse kidney carcinoma cell
Gene: Slc10a6 (solute carrier family 10 (sodium/bile acid cotransporter family), member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bile acid and bile salt transport, lipid transport, monoatomic ion transport, sodium ion transport, sodium-dependent organic anion tr...
Does Knockout of Tas2r131 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,261
Knockout
Tas2r131
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Tas2r131 (taste receptor, type 2, member 131) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of bitter taste, detection of chemical stimulus involved in sens...
Does Knockout of Gm5797 in small cell lung cancer causally result in cell proliferation?
1
1,714
Knockout
Gm5797
cell proliferation
small cell lung cancer
Gene: Gm5797 (predicted gene 5797) Type: protein-coding Summary: predicted gene 5797 Gene Ontology: Pathways: UniProt: Q5BKP9 Entrez ID: 545013
Does Knockout of Ppp2cb in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Ppp2cb
cell proliferation
Mouse kidney carcinoma cell
Gene: Ppp2cb (protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic mitochondrial changes, mitotic cell cycle, negative regulation of Ras protein signal transduction, negative regulation of canonica...
Does Knockout of Cdk6 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Cdk6
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Cdk6 (cyclin dependent kinase 6) Type: protein-coding Summary: This gene encodes a member of the cyclin dependent kinase family of proteins that play important roles in the progression and regulation of the cell cycle. The encoded protein binds to a D-type cyclin to form an active kinase complex t...
Does Knockout of Tnpo2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Tnpo2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Tnpo2 (transportin 2 (importin 3, karyopherin beta 2b)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular protein transport, negative regulation of muscle cell differentiation, nucleocytoplasmic transport, protein import into nucleus, protein transport; ...
Does Knockout of Angel1 in Melanoma Cell Line causally result in cell proliferation?
0
1,838
Knockout
Angel1
cell proliferation
Melanoma Cell Line
Gene: Angel1 (angel homolog 1) Type: protein-coding Summary: No summary available. Gene Ontology: MF: catalytic activity, eukaryotic initiation factor 4E binding, mRNA 3'-UTR binding, protein domain specific binding; CC: cis-Golgi network, cytosol, endoplasmic reticulum, mitochondrial outer mem...
Does Knockout of Zcchc8 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Zcchc8
phagocytosis
macrophage
Gene: Zcchc8 (zinc finger, CCHC domain containing 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA processing, RNA splicing, co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway, mRNA 3'-end processing, mRNA processing; MF: RNA binding, ...
Does Knockout of Ppdpf in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Ppdpf
cell proliferation
Mouse kidney carcinoma cell
Gene: Ppdpf (pancreatic progenitor cell differentiation and proliferation factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: TOR signaling, TORC1 signaling, cell differentiation, liver development Pathways: UniProt: Q9CR37 Entrez ID: 66496
Does Knockout of Qtrt1 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Qtrt1
response to virus
Microglial Cell Line
Gene: Qtrt1 (queuine tRNA-ribosyltransferase catalytic subunit 1) Type: protein-coding Summary: Enables tRNA-guanosine(34) queuine transglycosylase activity. Involved in tRNA-guanine transglycosylation. Located in cytoplasmic side of mitochondrial outer membrane and nucleus. Part of protein-containing c...
Does Knockout of Slc6a13 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Slc6a13
cell proliferation
Regulatory T cell
Gene: Slc6a13 (solute carrier family 6 (neurotransmitter transporter, GABA), member 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: amino acid import across plasma membrane, amino acid transport, creatine transmembrane transport, gamma-aminobutyric acid import, monoca...
Does Knockout of Smim12 in Melanoma Cell Line causally result in protein/peptide accumulation?
0
1,839
Knockout
Smim12
protein/peptide accumulation
Melanoma Cell Line
Gene: Smim12 (small integral membrane protein 12) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: Q78RX3 Entrez ID: 80284
Does Knockout of Tlcd2 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Tlcd2
response to virus
Neuroblastoma Cell Line
Gene: Tlcd2 (TLC domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: membrane assembly, phospholipid homeostasis, plasma membrane organization, regulation of membrane lipid distribution; CC: membrane, plasma membrane Pathways: UniProt: ...
Does Knockout of Nsl1 in pro-B-lymphocyte causally result in response to chemicals?
0
1,720
Knockout
Nsl1
response to chemicals
pro-B-lymphocyte
Gene: Nsl1 (NSL1, MIS12 kinetochore complex component) Type: protein-coding Summary: No summary available. Gene Ontology: BP: attachment of spindle microtubules to kinetochore, cell division, chromosome segregation, mitotic sister chromatid segregation; CC: MIS12/MIND type complex, chromosome, ...
Does Knockout of Zfp54 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Zfp54
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Zfp54 (zinc finger protein 54) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA po...
Does Knockout of Ecd in Microglial Cell Line causally result in response to virus?
0
1,438
Knockout
Ecd
response to virus
Microglial Cell Line
Gene: Ecd (ecdysoneless cell cycle regulator) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, fibroblast proliferation, mRNA processing, positive regulation of transcription by RNA polymerase II, regulation of G1/S transition of mitotic cell cycle; MF: histo...
Does Knockout of Fam53b in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Fam53b
cell proliferation
Mouse kidney carcinoma cell
Gene: Fam53b (family with sequence similarity 53, member B) Type: protein-coding Summary: Predicted to be involved in positive regulation of canonical Wnt signaling pathway and protein import into nucleus. Predicted to be active in nucleus. Is expressed in several structures, including central nervous s...
Does Knockout of Aff2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Aff2
protein/peptide accumulation
Embryonic Cell Line
Gene: Aff2 (AF4/FMR2 family, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, learning or memory, mRNA processing, negative regulation of gene expression, nuclear speck organization, regulation of RNA splicing, regulation of gene expression; MF: G-q...
Does Knockout of Rp1l1 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Rp1l1
response to chemicals
Pancreatic Cancer Cell Line
Gene: Rp1l1 (retinitis pigmentosa 1 homolog like 1) Type: protein-coding Summary: This gene encodes a member of the doublecortin family. This protein is a retinal-specific protein. It contains two N-terminal doublecortin domains, which can assemble and stabilize axonemal microtubules, but lacks the C-te...
Does Knockout of Ino80e in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,259
Knockout
Ino80e
cell proliferation
Mouse kidney carcinoma cell
Gene: Ino80e (INO80 complex subunit E) Type: protein-coding Summary: Predicted to be involved in several processes, including chromatin remodeling; regulation of chromosome organization; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in nucleolus and nucleopl...
Does Knockout of Hoxa9 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Hoxa9
protein/peptide distribution
Microglial Cell Line
Gene: Hoxa9 (homeobox A9) Type: protein-coding Summary: This gene is located in a cluster of developmentally and temporally regulated genes on chromosome 6 encoding proteins involved in pattern formation. These proteins contain a characteristic DNA-binding motif called a homeodomain and function in tran...
Does Knockout of Ell3 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,268
Knockout
Ell3
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Ell3 (elongation factor RNA polymerase II-like 3) Type: protein-coding Summary: Enables cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including positive regulation of transcription by RNA polymerase II; regulation of epithelial to mesenchymal transiti...
Does Knockout of Npm1 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Npm1
cell cycle progression
breast epithelium
Gene: Npm1 (nucleophosmin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair, cell volume homeostasis, cellular response to UV, cellular senescence, centrosome cycle, chromatin remodeling, cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA tra...
Does Knockout of Faiml in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Faiml
response to chemicals
Pancreatic Cancer Cell Line
Gene: Faiml (Fas apoptotic inhibitory molecule like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, negative regulation of apoptotic process, negative regulation of extrinsic apoptotic signaling pathway via death domain receptors, regulation of signal ...
Does Knockout of Morc2b in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Morc2b
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Morc2b (microrchidia 2B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, chromatin remodeling, constitutive heterochromatin formation, double-strand break repair involved in meiotic recombination, gamete generation, homologous chromosome pairing...
Does Knockout of Hagh in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Hagh
cell proliferation
Melanoma Cell Line
Gene: Hagh (hydroxyacyl glutathione hydrolase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glutathione biosynthetic process, glutathione metabolic process, methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione; MF: hydrolase activity, hydroxyacylgluta...
Does Knockout of Cdca7 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Cdca7
response to virus
Neuroblastoma Cell Line
Gene: Cdca7 (cell division cycle associated 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, regulation of DNA-templated transcription, regulation of cell population proliferation; MF: hemi-methylated DNA-binding, molecular_function; CC: cytoplasm, cy...
Does Knockout of Cyp4x1 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Cyp4x1
response to virus
Neuroblastoma Cell Line
Gene: Cyp4x1 (cytochrome P450, family 4, subfamily x, polypeptide 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid metabolic process, lipid metabolic process; MF: anandamide 14,15 epoxidase activity, heme binding, iron ion binding, metal ion binding, monooxyg...
Does Knockout of Agpat1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Agpat1
cell proliferation
Mouse kidney carcinoma cell
Gene: Agpat1 (1-acylglycerol-3-phosphate O-acyltransferase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CDP-diacylglycerol biosynthetic process, lipid metabolic process, phosphatidic acid biosynthetic process, phospholipid biosynthetic process, positive regulation o...
Does Knockout of Snapc5 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Snapc5
protein/peptide accumulation
Embryonic Cell Line
Gene: Snapc5 (small nuclear RNA activating complex, polypeptide 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: snRNA transcription by RNA polymerase II, snRNA transcription by RNA polymerase III, transcription by RNA polymerase II, transcription initiation at RNA poly...
Does Knockout of Chek2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Chek2
protein/peptide accumulation
Embryonic Cell Line
Gene: Chek2 (checkpoint kinase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage checkpoint signaling, DNA damage response, DNA damage response, signal transduction by p53 class mediator, DNA repair, G2/M transition of mitotic cell cycle, apoptotic process, au...
Does Knockout of Mup21 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Mup21
protein/peptide accumulation
Microglial Cell Line
Gene: Mup21 (major urinary protein 21) Type: protein-coding Summary: No summary available. Gene Ontology: MF: molecular_function, odorant binding, pheromone binding, small molecule binding; CC: extracellular region, extracellular space Pathways: UniProt: Q80YX8 Entrez...
Does Knockout of Stx3 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Stx3
phagocytosis
macrophage
Gene: Stx3 (syntaxin 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: exocytic insertion of neurotransmitter receptor to postsynaptic membrane, exocytosis, intracellular protein transport, long-term synaptic potentiation, membrane fusion, modulation of chemical synaptic...
Does Knockout of Drd1 in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Drd1
response to bacteria
renal medulla cell line
Gene: Drd1 (dopamine receptor D1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-glucose import, G protein-coupled dopamine receptor signaling pathway, G protein-coupled receptor signaling pathway, G protein-coupled receptor signaling pathway, coupled to cyclic nucleot...
Does Knockout of Itm2c in myoblast cell line causally result in protein/peptide distribution?
1
1,685
Knockout
Itm2c
protein/peptide distribution
myoblast cell line
Gene: Itm2c (integral membrane protein 2C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of amyloid precursor protein biosynthetic process, negative regulation of neuron projection development, neuron differentiation, positive regulation of extrinsic...
Does Knockout of Myef2 in macrophage causally result in phagocytosis?
0
1,890
Knockout
Myef2
phagocytosis
macrophage
Gene: Myef2 (myelin basic protein expression factor 2, repressor) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, RNA binding, RNA polymerase II cis-regulatory region sequence-specific ...
Does Knockout of Fnip1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Fnip1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Fnip1 (folliculin interacting protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, TORC1 signaling, cellular response to nutrient levels, cellular response to star...
Does Knockout of C8a in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
C8a
protein/peptide accumulation
Mouse cell
Gene: C8a (complement component 8, alpha polypeptide) Type: protein-coding Summary: This gene encodes the alpha subunit of complement component C8 that participates in the assembly of the complement membrane attack complex. The encoded preproprotein undergoes proteolytic processing to generate the alpha...
Does Knockout of Gm38119 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Gm38119
cell proliferation
Mouse kidney carcinoma cell
Gene: Gm38119 (predicted gene, 38119) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Serpinb6c in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Serpinb6c
protein/peptide distribution
Microglial Cell Line
Gene: Serpinb6c (serine (or cysteine) peptidase inhibitor, clade B, member 6c) Type: protein-coding Summary: Predicted to enable protease binding activity and serine-type endopeptidase inhibitor activity. Predicted to be involved in cellular response to osmotic stress; negative regulation of endopeptida...
Does Knockout of Tbc1d12 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Tbc1d12
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Tbc1d12 (TBC1D12: TBC1 domain family, member 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of autophagosome assembly, vesicle-mediated transport; MF: GTPase activator activity, enzyme binding; CC: autophagosome, cytoplasmic vesicle, endosome, recycl...
Does Knockout of Mapk4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Mapk4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mapk4 (mitogen-activated protein kinase 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, intracellular signal transduction; MF: ATP binding, MAP kinase activity, kinase activity, nucleotide binding, protein heterodimerization activity, protein homodi...
Does Knockout of Fam124a in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Fam124a
protein/peptide accumulation
Microglial Cell Line
Gene: Fam124a (family with sequence similarity 124, member A) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: D3Z5V4 Entrez ID: 629059
Does Knockout of Sema3e in macrophage causally result in phagocytosis?
0
1,888
Knockout
Sema3e
phagocytosis
macrophage
Gene: Sema3e (sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, axon guidance, branching involved in blood vessel morphogenesis, cell differentiation, gonadotrophin-releasi...
Does Knockout of Mbd4 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Mbd4
tumorigenicity
Colonic Cancer Cell Line
Gene: Mbd4 (methyl-CpG binding domain protein 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, intrinsic apoptotic signaling pathway in response to DNA damage, mitotic G2 DNA damage checkpoint signaling, response to radiation; MF: DNA bi...
Does Knockout of Tbc1d1 in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Tbc1d1
response to bacteria
renal medulla cell line
Gene: Tbc1d1 (TBC1 domain family, member 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of insulin secretion involved in cellular response to glucose stimulus, regulation of protein localization; MF: GTPase activator activity, protein binding; CC: ...
Does Knockout of Hes2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Hes2
cell proliferation
Mouse kidney carcinoma cell
Gene: Hes2 (hes family bHLH transcription factor 2) Type: protein-coding Summary: The protein encoded by this gene belongs to the mammalian Hes gene family, the mammalian homologues of Drosophila hairy and Enhancer of split. Hes 2 is a basic helix-loop-helix transcriptional repressor and is an effector ...
Does Knockout of Adgra3 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,178
Knockout
Adgra3
tumorigenicity
Colonic Cancer Cell Line
Gene: Adgra3 (adhesion G protein-coupled receptor A3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, cell surface receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity, transmembrane signali...
Does Knockout of Tcf12 in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Tcf12
cell cycle progression
breast epithelium
Gene: Tcf12 (transcription factor 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, nervous system development, positive regulation of DNA-templated transcription, positive regulation of gene expression, positive regulation of neuron differentiatio...
Does Knockout of Stat1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,261
Knockout
Stat1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Stat1 (signal transducer and activator of transcription 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA-templated transcription, blood circulation, cell population proliferation, cell surface receptor signaling pathway via JAK-STAT, cell surface receptor sign...
Does Knockout of Hif1an in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Hif1an
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Hif1an (hypoxia-inducible factor 1, alpha subunit inhibitor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of Notch signaling pathway, negative regulation of transcription by RNA polymerase II, positive regulation of myoblast differentiation, r...
Does Knockout of Cyp4a30b in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Cyp4a30b
protein/peptide distribution
myoblast cell line
Gene: Cyp4a30b (cytochrome P450, family 4, subfamily a, polypeptide 30b) Type: protein-coding Summary: Predicted to enable 16-hydroxypalmitate dehydrogenase activity and monooxygenase activity. Predicted to be involved in fatty acid metabolic process; icosanoid biosynthetic process; and kidney developme...
Does Knockout of Pkia in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Pkia
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Pkia (protein kinase inhibitor, alpha) Type: protein-coding Summary: Enables cAMP-dependent protein kinase inhibitor activity and protein kinase A catalytic subunit binding activity. Acts upstream of or within negative regulation of macromolecule metabolic process; negative regulation of protein i...
Does Knockout of Trpv6 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Trpv6
cell proliferation
Mouse kidney carcinoma cell
Gene: Trpv6 (transient receptor potential cation channel, subfamily V, member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion homeostasis, calcium ion import, calcium ion import across plasma membrane, calcium ion transmembrane transport, calcium ion transp...
Does Knockout of Fan1 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Fan1
protein/peptide accumulation
Mouse cell
Gene: Fan1 (FANCD2/FANCI-associated nuclease 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, double-strand break repair via homologous recombination, interstrand cross-link repair, nucleotide-excision repair; MF: 5'-3' exonuclease activ...
Does Knockout of Cdh4 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,266
Knockout
Cdh4
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cdh4 (cadherin 4) Type: protein-coding Summary: This gene encodes a member of the cadherin family of calcium-dependent glycoproteins that mediate cell adhesion and regulate many morphogenetic events during development. The encoded preproprotein is further processed to generate a mature protein. Th...
Does Knockout of Ccdc47 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Ccdc47
cell proliferation
Mouse kidney carcinoma cell
Gene: Ccdc47 (coiled-coil domain containing 47) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ER overload response, ERAD pathway, calcium ion homeostasis, endoplasmic reticulum calcium ion homeostasis, endoplasmic reticulum organization, multi-pass transmembrane protein...
Does Knockout of Dgkz in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Dgkz
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Dgkz (diacylglycerol kinase zeta) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Ras protein signal transduction, diacylglycerol metabolic process, glycerolipid metabolic process, intracellular signal transduction, lipid metabolic process, lipid phosphorylation, ma...
Does Knockout of Plagl2 in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Plagl2
cell proliferation
Regulatory T cell
Gene: Plagl2 (pleiomorphic adenoma gene-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chylomicron assembly, lipid metabolic process, positive regulation of intrinsic apoptotic signaling pathway, positive regulation of transcription by RNA polymerase II, post-emb...
Does Knockout of Ust in Regulatory T cell causally result in protein/peptide accumulation?
0
1,481
Knockout
Ust
protein/peptide accumulation
Regulatory T cell
Gene: Ust (uronyl-2-sulfotransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: dermatan sulfate proteoglycan biosynthetic process, establishment of cell polarity, regulation of axonogenesis; MF: 3'-phosphoadenosine 5'-phosphosulfate binding, chondroitin 2-sulfotran...
Does Knockout of Gprin3 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Gprin3
cell proliferation
Melanoma Cell Line
Gene: Gprin3 (GPRIN family member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell morphogenesis involved in neuron differentiation, excitatory chemical synaptic transmission, locomotory behavior, neuron projection development, neuronal action potential, response t...
Does Knockout of Utf1 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Utf1
cell proliferation
Embryonic Stem Cell Line
Gene: Utf1 (undifferentiated embryonic cell transcription factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of transcription by RNA polymerase II; MF: HMG box domain binding, TBP-class protein binding, protein binding, transcription coactivator...
Does Knockout of Bhlha15 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,268
Knockout
Bhlha15
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Bhlha15 (basic helix-loop-helix family, member a15) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, Golgi organization, axon development, calcium-mediated signaling, cell differentiation, cell-cell adhesion mediated by c...
Does Knockout of Hace1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,268
Knockout
Hace1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Hace1 (HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, membrane fusion, protein K48-linked ubiquitination, protein ubiquitination, regulation of cell migration, ubiquitin-d...
Does Knockout of Dcps in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Dcps
protein/peptide distribution
myoblast cell line
Gene: Dcps (decapping enzyme, scavenger) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, deadenylation-dependent decapping of nuclear-transcribed mRNA, mRNA cis splicing, via spliceosome, mRNA methylguanosine-cap decapping, mRNA processing, nuclear-transcrib...
Does Knockout of Cetn4 in Melanoma Cell Line causally result in cell proliferation?
0
1,281
Knockout
Cetn4
cell proliferation
Melanoma Cell Line
Gene: Cetn4 (centrin 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: centriole replication, microtubule cytoskeleton organization; MF: G-protein beta/gamma-subunit complex binding, calcium ion binding, heterotrimeric G-protein binding, metal ion binding; CC: centriole,...