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Does Knockout of Fam76b in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,398
Knockout
Fam76b
protein/peptide accumulation
Microglial Cell Line
Gene: Fam76b (family with sequence similarity 76, member B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA stabilization, negative regulation of inflammatory response, negative regulation of macrophage activation, negative regulation of protein export from nucleus; ...
Does Knockout of Casr in Regulatory T cell causally result in cell proliferation?
0
1,483
Knockout
Casr
cell proliferation
Regulatory T cell
Gene: Casr (calcium-sensing receptor) Type: protein-coding Summary: Predicted to enable several functions, including integrin binding activity; protein homodimerization activity; and transmembrane transporter binding activity. Involved in regulation of presynaptic membrane potential. Acts upstream of or...
Does Knockout of Phactr3 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Phactr3
response to virus
Neuroblastoma Cell Line
Gene: Phactr3 (phosphatase and actin regulator 3) Type: protein-coding Summary: No summary available. Gene Ontology: MF: actin binding, protein phosphatase inhibitor activity; CC: nuclear matrix, nucleoplasm, nucleus Pathways: UniProt: Q8BYK5 Entrez ID: 74189
Does Knockout of Nxph2 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
1,565
Knockout
Nxph2
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Nxph2 (neurexophilin 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: signaling receptor binding Pathways: UniProt: Q61199 Entrez ID: 18232
Does Knockout of Bet1l in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Bet1l
cell proliferation
Mouse kidney carcinoma cell
Gene: Bet1l (Bet1 golgi vesicular membrane trafficking protein like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: membrane fusion, protein transport, regulation of retrograde vesicle-mediated transport, Golgi to ER, retrograde transport, endosome to Golgi; MF: SNAP rec...
Does Knockout of Rgl3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Rgl3
cell proliferation
Mouse kidney carcinoma cell
Gene: Rgl3 (ral guanine nucleotide dissociation stimulator-like 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Ras protein signal transduction, signal transduction, small GTPase-mediated signal transduction; MF: guanyl-nucleotide exchange factor activity, protein bind...
Does Knockout of Pglyrp4 in Melanoma Cell Line causally result in cell proliferation?
0
2,488
Knockout
Pglyrp4
cell proliferation
Melanoma Cell Line
Gene: Pglyrp4 (peptidoglycan recognition protein 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antimicrobial humoral immune response mediated by antimicrobial peptide, biological process involved in interaction with host, defense response to Gram-positive bacterium, ...
Does Knockout of Tagln2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Tagln2
cell proliferation
Mouse kidney carcinoma cell
Gene: Tagln2 (transgelin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin filament organization, epithelial cell differentiation Pathways: Hemostasis, Platelet activation, signaling and aggregation, Platelet degranulation , Response to elevated platelet c...
Does Knockout of Bsnd in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Bsnd
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Bsnd (barttin CLCNK type accessory beta subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chloride transmembrane transport, chloride transport, intracellular chloride ion homeostasis, intracellular monoatomic ion homeostasis, intracellular potassium ion homeo...
Does Knockout of Arhgef1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
1,664
Knockout
Arhgef1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Arhgef1 (Rho guanine nucleotide exchange factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, Rho-activating G protein-coupled receptor signaling pathway, microtubule depolymerization; MF: G protein-coupled receptor...
Does Knockout of Hspa4l in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Hspa4l
cell proliferation
Mouse kidney carcinoma cell
Gene: Hspa4l (heat shock protein 4 like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein folding, response to unfolded protein; MF: ATP binding, ATP-dependent protein folding chaperone, adenyl-nucleotide exchange factor activity, nucleotide binding, protein bindin...
Does Knockout of Cyb5r2 in Cytotoxic T-lymphocyte (CD8+ T cells) causally result in cell proliferation?
1
2,411
Knockout
Cyb5r2
cell proliferation
Cytotoxic T-lymphocyte (CD8+ T cells)
Gene: Cyb5r2 (cytochrome b5 reductase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid metabolic process, steroid biosynthetic process, steroid metabolic process, sterol biosynthetic process; MF: FAD binding, cytochrome-b5 reductase activity, acting on NAD(P)H, ox...
Does Knockout of Adam28 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Adam28
cell proliferation
Mouse kidney carcinoma cell
Gene: Adam28 (a disintegrin and metallopeptidase domain 28) Type: protein-coding Summary: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are typically membrane-anchored, although a form of this protein may be secreted. Alternative splicin...
Does Knockout of Rsbn1l in Melanoma Cell Line causally result in cell proliferation?
0
1,282
Knockout
Rsbn1l
cell proliferation
Melanoma Cell Line
Gene: Rsbn1l (round spermatid basic protein 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: MF: dioxygenase activity, metal ion binding, molecular_function, oxidoreductase activity; CC: nucleus Pathways: UniProt: A0A0G2JDQ6, D3Z0K6, A0A0G2JEI9 ...
Does Knockout of Hoxb4 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Hoxb4
protein/peptide distribution
myoblast cell line
Gene: Hoxb4 (homeobox B4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterior/posterior pattern specification, bone marrow development, definitive hemopoiesis, embryonic organ morphogenesis, embryonic skeletal system morphogenesis, hematopoietic stem cell differentia...
Does Knockout of Magt1 in myoblast cell line causally result in protein/peptide distribution?
0
1,680
Knockout
Magt1
protein/peptide distribution
myoblast cell line
Gene: Magt1 (magnesium transporter 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cognition, magnesium ion transmembrane transport, magnesium ion transport, protein N-linked glycosylation, protein N-linked glycosylation via asparagine, protein glycosylation; CC: endop...
Does Knockout of Gm527 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Gm527
cell proliferation
Mouse kidney carcinoma cell
Gene: Gm527 (predicted gene 527) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled dopamine receptor signaling pathway, NMDA selective glutamate receptor signaling pathway, biological_process, cAMP-mediated signaling, gene expression, memory, neurogenesis ...
Does Knockout of Phyhipl in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Phyhipl
cell proliferation
Colonic Cancer Cell Line
Gene: Phyhipl (phytanoyl-CoA hydroxylase interacting protein-like) Type: protein-coding Summary: Located in mitochondrion. Is expressed in several structures, including nervous system; neural retina; and olfactory epithelium. Orthologous to human PHYHIPL (phytanoyl-CoA 2-hydroxylase interacting protein ...
Does Knockout of Kdm4c in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Kdm4c
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Kdm4c (lysine (K)-specific demethylase 4C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: androgen receptor signaling pathway, blastocyst formation, chromatin organization, chromatin remodeling, positive regulation of cell population proliferation, positive regulat...
Does Knockout of Vps18 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Vps18
cell viability
Immortal mouse chromaffin cells
Gene: Vps18 (VPS18 CORVET/HOPS core subunit) Type: protein-coding Summary: Enables actin binding activity. Acts upstream of or within endosome organization and symbiont entry into host cell. Located in actin filament and early endosome. Part of AP-3 adaptor complex and CORVET complex. Is expressed in al...
Does Knockout of Fap in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Fap
protein/peptide distribution
myoblast cell line
Gene: Fap (fibroblast activation protein) Type: protein-coding Summary: This gene belongs to the serine protease family. The encoded protein is an inducible cell-surface bound glycoprotein specifically expressed in tumor-associated fibroblasts and pericytes of epithelial tumors and has protease and gela...
Does Knockout of Ggct in Melanoma Cell Line causally result in tumorigenicity?
0
2,187
Knockout
Ggct
tumorigenicity
Melanoma Cell Line
Gene: Ggct (gamma-glutamyl cyclotransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: release of cytochrome c from mitochondria; MF: gamma-glutamylcyclotransferase activity, lyase activity, protein homodimerization activity; CC: cytosol Pathways: γ-g...
Does Knockout of Parm1 in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Parm1
cell cycle progression
breast epithelium
Gene: Parm1 (prostate androgen-regulated mucin-like protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: CC: Golgi apparatus, Golgi membrane, cytosol, early endosome, endosome, endosome membrane, late endosome, membrane, nucleoplasm, plasma membrane Pathways: ...
Does Knockout of Slc44a3 in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
Slc44a3
response to chemicals
Pancreatic Cancer Cell Line
Gene: Slc44a3 (solute carrier family 44, member 3) Type: protein-coding Summary: Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Is expressed in gut and olfactory epithelium. Orthologous to human SLC44A3 (so...
Does Knockout of Gpr149 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Gpr149
protein/peptide accumulation
Microglial Cell Line
Gene: Gpr149 (G protein-coupled receptor 149) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, antral ovarian follicle growth, negative regulation of ovulation, neuropeptide signaling pathway, preantral ovarian follicle growth,...
Does Knockout of Vps45 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Vps45
cell proliferation
Melanoma Cell Line
Gene: Vps45 (vacuolar protein sorting 45) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular protein transport, protein transport, vesicle-mediated transport; CC: Golgi apparatus, Golgi membrane, cytoplasmic vesicle, endosome, endosome membrane, membrane, synap...
Does Knockout of Pam in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Pam
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Pam (peptidylglycine alpha-amidating monooxygenase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to oxidative stress, fatty acid primary amide biosynthetic process, lipid metabolic process, long-chain fatty acid metabolic process, peptide amidat...
Does Knockout of BC051665 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
BC051665
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: BC051665 (cDNA sequence BC051665) Type: protein-coding Summary: No summary available. Gene Ontology: BP: collagen catabolic process, fusion of virus membrane with host endosome membrane, fusion of virus membrane with host plasma membrane, protein autoprocessing, proteolysis, proteolysis i...
Does Knockout of Nfu1 in myoblast cell line causally result in protein/peptide distribution?
0
1,680
Knockout
Nfu1
protein/peptide distribution
myoblast cell line
Gene: Nfu1 (NFU1 iron-sulfur cluster scaffold) Type: protein-coding Summary: No summary available. Gene Ontology: BP: iron-sulfur cluster assembly, protein maturation; MF: 2 iron, 2 sulfur cluster binding, 4 iron, 4 sulfur cluster binding, iron ion binding, iron-sulfur cluster binding, metal io...
Does Knockout of Prok2 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Prok2
protein/peptide distribution
myoblast cell line
Gene: Prok2 (prokineticin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, chemotaxis, circadian rhythm, coronary vasculature development, endothelial cell proliferation, epicardium-derived cardiac endothelial cell differentiation, epicardium-derived cardi...
Does Knockout of Jph2 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Jph2
protein/peptide accumulation
Mouse cell
Gene: Jph2 (junctophilin 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: calcium ion homeostasis, negative regulation of DNA-templated transcription, negative regulation of transcription by RNA polymerase II, positive regulation of cytosolic calcium ion concentration, ...
Does Knockout of Csdc2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Csdc2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Csdc2 (cold shock domain containing C2, RNA binding) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA processing, regulation of mRNA stability; MF: RNA binding, mRNA 3'-UTR binding, nucleic acid binding; CC: cytoplasm, nucleus Pathways: UniPro...
Does Knockout of H60c in myoblast cell line causally result in protein/peptide distribution?
1
1,685
Knockout
H60c
protein/peptide distribution
myoblast cell line
Gene: H60c (histocompatibility 60c) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent, antigen processing and presentation of endogenous peptide antigen via MHC...
Does Knockout of Gm17455 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Gm17455
response to virus
Embryonic Fibroblast Cell Line
Gene: Gm17455 (predicted gene, 17455) Type: protein-coding Summary: Orthologous to human C10orf105 (chromosome 10 open reading frame 105). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: Pathways: UniProt: A0A3B2WBH3, G3UW87, A0A3B2WAM3 Entrez ID:...
Does Knockout of Sptan1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Sptan1
protein/peptide accumulation
Embryonic Cell Line
Gene: Sptan1 (spectrin alpha, non-erythrocytic 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: actin cytoskeleton organization, actin filament capping; MF: actin binding, actin filament binding, calcium ion binding, calmodulin binding, metal ion binding, protein bindin...
Does Knockout of Dyrk3 in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Dyrk3
cell proliferation
Melanoma Cell Line
Gene: Dyrk3 (dual-specificity tyrosine phosphorylation regulated kinase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, erythrocyte differentiation, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulatio...
Does Knockout of Fars2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
81
Knockout
Fars2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Fars2 (phenylalanine-tRNA synthetase 2, mitochondrial) Type: protein-coding Summary: No summary available. Gene Ontology: BP: phenylalanyl-tRNA aminoacylation, tRNA aminoacylation, tRNA processing, translation; MF: ATP binding, aminoacyl-tRNA ligase activity, ligase activity, nucleotide b...
Does Knockout of Gpr45 in Microglial Cell Line causally result in phagocytosis?
0
1,587
Knockout
Gpr45
phagocytosis
Microglial Cell Line
Gene: Gpr45 (G protein-coupled receptor 45) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: G alpha (s) signalling ...
Does Knockout of Ifit1 in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Ifit1
response to virus
Microglial Cell Line
Gene: Ifit1 (interferon-induced protein with tetratricopeptide repeats 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to interferon-alpha, cellular response to interferon-beta, defense response to virus, immune system process, innate immune response,...
Does Knockout of Rnf20 in Lung Cancer Cell Line causally result in tumorigenicity?
0
1,781
Knockout
Rnf20
tumorigenicity
Lung Cancer Cell Line
Gene: Rnf20 (ring finger protein 20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: chromatin organization, chromatin remodeling, negative regulation of cell migration, positive regulation of DNA-templated transcription, positive regulation of transcription by RNA polyme...
Does Knockout of Slco4c1 in macrophage causally result in phagocytosis?
0
1,890
Knockout
Slco4c1
phagocytosis
macrophage
Gene: Slco4c1 (solute carrier organic anion transporter family, member 4C1) Type: protein-coding Summary: Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be active in basolateral...
Does Knockout of Srm in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Srm
protein/peptide accumulation
Regulatory T cell
Gene: Srm (spermidine synthase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to leukemia inhibitory factor, polyamine biosynthetic process, polyamine metabolic process, spermidine biosynthetic process; MF: catalytic activity, identical protein binding...
Does Knockout of Slc6a3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,260
Knockout
Slc6a3
cell proliferation
Mouse kidney carcinoma cell
Gene: Slc6a3 (solute carrier family 6 (neurotransmitter transporter, dopamine), member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adenohypophysis development, amino acid transport, cognition, dopamine biosynthetic process, dopamine catabolic process, dopamine tran...
Does Knockout of Dcun1d5 in myoblast cell line causally result in protein/peptide distribution?
1
1,683
Knockout
Dcun1d5
protein/peptide distribution
myoblast cell line
Gene: Dcun1d5 (defective in cullin neddylation 1 domain containing 5) Type: protein-coding Summary: Predicted to enable cullin family protein binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin-like protein binding activity. Predicted to be involved in several processes, inclu...
Does Knockout of Fgf21 in pro-B-lymphocyte causally result in response to chemicals?
0
1,720
Knockout
Fgf21
response to chemicals
pro-B-lymphocyte
Gene: Fgf21 (fibroblast growth factor 21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fibroblast growth factor receptor signaling pathway, negative regulation of endothelial cell apoptotic process, neurogenesis, positive regulation of D-glucose import, positive regula...
Does Knockout of Rhox4f in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Rhox4f
cell proliferation
Embryonic Stem Cell Line
Gene: Rhox4f (reproductive homeobox 4F) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, positive regulation of transcription by RNA polymerase II, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription activator ac...
Does Knockout of Col5a1 in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Col5a1
cell proliferation
Regulatory T cell
Gene: Col5a1 (collagen, type V, alpha 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: blood vessel development, cell adhesion, cell migration, collagen biosynthetic process, collagen fibril organization, eye morphogenesis, heart morphogenesis, integrin biosynthetic pro...
Does Knockout of Cilp2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Cilp2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Cilp2 (cartilage intermediate layer protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: carbohydrate binding, molecular_function; CC: extracellular region, extracellular space Pathways: UniProt: D3Z7H8 Entrez ID: 68709
Does Knockout of Spag6l in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
Spag6l
protein/peptide accumulation
Embryonic Cell Line
Gene: Spag6l (sperm associated antigen 6-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, cell projection organization, cerebrospinal fluid circulation, ear development, epithelial cilium movement involved in extracellular fluid movement, establishment...
Does Knockout of Phactr4 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Phactr4
protein/peptide accumulation
Microglial Cell Line
Gene: Phactr4 (phosphatase and actin regulator 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rho protein signal transduction, actin cytoskeleton organization, closure of optic fissure, enteric nervous system development, negative regulation of integrin-mediated signa...
Does Knockout of Vps53 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Vps53
cell proliferation
Mouse kidney carcinoma cell
Gene: Vps53 (VPS53 GARP complex subunit) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytosolic transport, endocytic recycling, lysosomal transport, protein targeting to lysosome, protein transport, retrograde transport, endosome to Golgi, vesicle-mediated cholesterol ...
Does Knockout of Tpbpa in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Tpbpa
cell proliferation
Mouse kidney carcinoma cell
Gene: Tpbpa (trophoblast specific protein alpha) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A0A286YCU7, Q9CPR0, A0A286YCI4 Entrez ID: 21984
Does Knockout of 1810065E05Rik in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
1810065E05Rik
cell proliferation
Melanoma Cell Line
Gene: 1810065E05Rik (RIKEN cDNA 1810065E05 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9D8K1, Q5NC41 Entrez ID: 69864
Does Knockout of Dpf2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Dpf2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Dpf2 (double PHD fingers 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, chromatin organization, chromatin remodeling, negative regulation of myeloid progenitor cell differentiation, nervous system development, positive regulation of double-str...
Does Knockout of Klrb1b in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Klrb1b
cell proliferation
Regulatory T cell
Gene: Klrb1b (killer cell lectin-like receptor subfamily B member 1B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of natural killer cell mediated cytotoxicity, regulation of natural killer cell mediated cytotoxicity; MF: carbohydrate binding, ident...
Does Knockout of 6030458C11Rik in myoblast cell line causally result in protein/peptide distribution?
0
1,680
Knockout
6030458C11Rik
protein/peptide distribution
myoblast cell line
Gene: 6030458C11Rik (RIKEN cDNA 6030458C11 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8BGC1 Entrez ID: 77877
Does Knockout of Akr1a1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Akr1a1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Akr1a1 (aldo-keto reductase family 1, member A1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: D-glucuronate catabolic process, D-glucuronate catabolic process to D-xylulose 5-phosphate, L-ascorbic acid biosynthetic process, aldehyde catabolic process, cellular de...
Does Knockout of 4930474N05Rik in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,261
Knockout
4930474N05Rik
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: 4930474N05Rik (RIKEN cDNA 4930474N05 gene) Type: protein-coding Summary: No summary available. Gene Ontology: MF: guanyl-nucleotide exchange factor activity, molecular_function Pathways: UniProt: Q3V0P0, Q8BVR5 Entrez ID: 218921
Does Knockout of Map3k21 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Map3k21
cell proliferation
Mouse kidney carcinoma cell
Gene: Map3k21 (mitogen-activated protein kinase kinase kinase 21) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MAPK cascade, signal transduction; MF: ATP binding, JUN kinase kinase kinase activity, MAP kinase kinase kinase activity, kinase activity, nucleotide binding,...
Does Knockout of Ear-ps2 in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Ear-ps2
protein/peptide distribution
Microglial Cell Line
Gene: Ear-ps2 (eosinophil-associated, ribonuclease A family, pseudogene 2) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Itgae in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Itgae
cell proliferation
Mouse kidney carcinoma cell
Gene: Itgae (integrin alpha E, epithelial-associated) Type: protein-coding Summary: Predicted to enable integrin binding activity. Predicted to be involved in several processes, including cell adhesion mediated by integrin; cell-matrix adhesion; and integrin-mediated signaling pathway. Located in extern...
Does Knockout of Gaa in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Gaa
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Gaa (glucosidase, alpha, acid) Type: protein-coding Summary: This gene encodes a lysosomal acid glucosidase that is involved in the degradation of glycogen. The encoded preproprotein undergoes proteolytic processing to generate a mature enzyme that cleaves alpha-1-4 and alpha-1-6 glycosidic bonds ...
Does Knockout of Ccdc40 in Embryonic Cell Line causally result in protein/peptide accumulation?
1
1,440
Knockout
Ccdc40
protein/peptide accumulation
Embryonic Cell Line
Gene: Ccdc40 (coiled-coil domain containing 40) Type: protein-coding Summary: No summary available. Gene Ontology: BP: axonemal dynein complex assembly, axoneme assembly, cilium movement, determination of digestive tract left/right asymmetry, determination of left/right symmetry, determination ...
Does Knockout of Hax1 in macrophage causally result in phagocytosis?
0
1,890
Knockout
Hax1
phagocytosis
macrophage
Gene: Hax1 (HCLS1 associated X-1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway, cellular response to cytokine stimulus, granulocyte colony-stimulating factor signaling pathway, negative regulation of apoptotic process, positive r...
Does Knockout of 4933409G03Rik in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
4933409G03Rik
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: 4933409G03Rik (RIKEN cDNA 4933409G03 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: F6YRC2, Q8C5U0 Entrez ID: 227998
Does Knockout of Mybph in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Mybph
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Mybph (myosin binding protein H) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, sarcomere organization; CC: M band, myosin filament Pathways: UniProt: P70402 Entrez ID: 53311
Does Knockout of Gls2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,663
Knockout
Gls2
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Gls2 (glutaminase 2 (liver, mitochondrial)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: L-glutamine catabolic process, glutamate biosynthetic process, glutamine metabolic process, reactive oxygen species metabolic process, regulation of apoptotic process; MF: gl...
Does Knockout of Pelp1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Pelp1
protein/peptide accumulation
Embryonic Cell Line
Gene: Pelp1 (proline, glutamic acid and leucine rich protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to estrogen stimulus, positive regulation of transcription by RNA polymerase II, rRNA processing; MF: SUMO binding, chromatin binding, protein...
Does Knockout of Rad9b in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Rad9b
response to virus
Neuroblastoma Cell Line
Gene: Rad9b (RAD9 checkpoint clamp component B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage checkpoint signaling, DNA repair, DNA replication checkpoint signaling, cellular response to ionizing radiation, mitotic intra-S DNA damage checkpoint signaling; CC:...
Does Knockout of Gucy2g in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Gucy2g
protein/peptide distribution
Microglial Cell Line
Gene: Gucy2g (guanylate cyclase 2g) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cGMP biosynthetic process, cyclic nucleotide biosynthetic process, intracellular signal transduction, receptor guanylyl cyclase signaling pathway; MF: ATP binding, GTP binding, guanylate c...
Does Knockout of Gc in macrophage causally result in phagocytosis?
0
1,889
Knockout
Gc
phagocytosis
macrophage
Gene: Gc (vitamin D binding protein) Type: protein-coding Summary: Predicted to enable actin binding activity and calcidiol binding activity. Acts upstream of or within vitamin D metabolic process. Predicted to be located in axon; extracellular space; and perinuclear region of cytoplasm. Predicted to be...
Does Knockout of Map3k15 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Map3k15
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Map3k15 (mitogen-activated protein kinase kinase kinase 15) Type: protein-coding Summary: Predicted to enable MAP kinase kinase kinase activity. Predicted to be involved in JNK cascade and p38MAPK cascade. Is expressed in pancreas. Orthologous to human MAP3K15 (mitogen-activated protein kinase kin...
Does Knockout of Mterf2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
Mterf2
protein/peptide accumulation
Embryonic Cell Line
Gene: Mterf2 (mitochondrial transcription termination factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, nucleic acid binding; CC: mitochondrial matrix, mitochondrial nucleoid, mitochondrion Pathways: UniProt: Q8BKY8 Entrez I...
Does Knockout of Pdpn in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Pdpn
cell proliferation
Colonic Cancer Cell Line
Gene: Pdpn (podoplanin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rho protein signal transduction, actin-mediated cell contraction, amino acid transport, cell adhesion, cell migration, cell population proliferation, cell-cell adhesion, folic acid transport, lung alv...
Does Knockout of Tlx1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,271
Knockout
Tlx1
cell proliferation
Mouse kidney carcinoma cell
Gene: Tlx1 (T cell leukemia, homeobox 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, animal organ formation, cell fate commitment, central nervous system development, lymph node development, neuron differentiation, positive regulation of stem...
Does Knockout of Ints3 in Mouse kidney carcinoma cell causally result in cell proliferation?
1
1,271
Knockout
Ints3
cell proliferation
Mouse kidney carcinoma cell
Gene: Ints3 (integrator complex subunit 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, RNA polymerase II transcription initiation surveillance, double-strand break repair via homologous recombination, mitotic G2/M transition checkpoint...
Does Knockout of Pdha2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Pdha2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Pdha2 (pyruvate dehydrogenase E1 alpha 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glucose metabolic process, pyruvate decarboxylation to acetyl-CoA, tricarboxylic acid cycle; MF: metal ion binding, oxidoreductase activity, oxidoreductase activity, acting on ...
Does Knockout of Gsdmc in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
1,565
Knockout
Gsdmc
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Gsdmc (gasdermin C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to bacterium, programmed cell death, pyroptotic inflammatory response; MF: phosphatidylinositol-4,5-bisphosphate binding, phosphatidylinositol-4-phosphate binding, phosphatidylserin...
Does Knockout of Cebpg in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,263
Knockout
Cebpg
cell proliferation
Colonic Cancer Cell Line
Gene: Cebpg (CCAAT/enhancer binding protein gamma) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell differentiation, DNA-templated transcription, chromatin remodeling, enucleate erythrocyte differentiation, immune response, liver development, mRNA metabolic process,...
Does Knockout of Manba in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Manba
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Manba (mannosidase, beta A, lysosomal) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate metabolic process, glycoprotein catabolic process; MF: D-mannose binding, beta-mannosidase activity, hydrolase activity, hydrolase activity, acting on glycosyl bonds,...
Does Knockout of Tapbp in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Tapbp
protein/peptide distribution
myoblast cell line
Gene: Tapbp (TAP binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: MHC class Ib protein complex assembly, antigen processing and presentation of endogenous peptide antigen via MHC class I, antigen processing and presentation of exogenous peptide antigen via...
Does Knockout of Hcst in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Hcst
cell proliferation
Embryonic Stem Cell Line
Gene: Hcst (hematopoietic cell signal transducer) Type: protein-coding Summary: No summary available. Gene Ontology: BP: natural killer cell mediated cytotoxicity, positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction, regulation of immune response; MF: phosp...
Does Knockout of Tnfrsf11a in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Tnfrsf11a
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Tnfrsf11a (tumor necrosis factor receptor superfamily, member 11a, NFKB activator) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, cellular response to zinc ion starvation, circadian temperature homeostasis, immune system process, lymph nod...
Does Knockout of Rfc2 in Embryonic Fibroblast Cell Line causally result in cell proliferation?
1
345
Knockout
Rfc2
cell proliferation
Embryonic Fibroblast Cell Line
Gene: Rfc2 (replication factor C (activator 1) 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA repair, DNA replication, DNA-templated DNA replication, positive regulation of DNA-directed DNA polymerase activity; MF: ATP binding, ATP hydrolysis activity, DNA binding...
Does Knockout of Irs2 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Irs2
cell viability
Immortal mouse chromaffin cells
Gene: Irs2 (insulin receptor substrate 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: brain development, cellular response to endothelin, cellular response to glucose stimulus, cellular response to insulin stimulus, epithelial cell migration, insulin receptor signalin...
Does Knockout of Yme1l1 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Yme1l1
protein/peptide accumulation
Microglial Cell Line
Gene: Yme1l1 (YME1-like 1 (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell population proliferation, cellular response to starvation, mitochondrial protein catabolic process, mitochondrial protein processing, mitochondrion organization, negative regul...
Does Knockout of Foxn4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
82
Knockout
Foxn4
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Foxn4 (forkhead box N4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: amacrine cell differentiation, atrioventricular canal development, heart looping, nervous system development, neuron fate commitment, positive regulation of transcription by RNA polymerase II, r...
Does Knockout of Nhs in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,259
Knockout
Nhs
cell proliferation
Mouse kidney carcinoma cell
Gene: Nhs (NHS actin remodeling regulator) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, lens development in camera-type eye; CC: Golgi apparatus, cell junction, nuclear body Pathways: RAC1 GTPase cycle, RAC2 GTPase cycle, RAC3 GTPase cycl...
Does Knockout of Igf2bp3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Igf2bp3
cell proliferation
Mouse kidney carcinoma cell
Gene: Igf2bp3 (insulin-like growth factor 2 mRNA binding protein 3) Type: protein-coding Summary: Predicted to enable N6-methyladenosine-containing RNA reader activity; mRNA 3'-UTR binding activity; and mRNA 5'-UTR binding activity. Predicted to be involved in CRD-mediated mRNA stabilization and nervous...
Does Knockout of Polr3f in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Polr3f
cell proliferation
Regulatory T cell
Gene: Polr3f (polymerase (RNA) III (DNA directed) polypeptide F) Type: protein-coding Summary: No summary available. Gene Ontology: BP: defense response to virus, immune system process, innate immune response, positive regulation of innate immune response, positive regulation of interferon-beta...
Does Knockout of Mkx in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Mkx
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Mkx (mohawk homeobox) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, cell development, cellular response to mechanical stimulus, collagen fibril organization, intratendonous ossification, muscle organ development, negative regulation of ch...
Does Knockout of Fgf23 in Regulatory T cell causally result in cell proliferation?
0
1,483
Knockout
Fgf23
cell proliferation
Regulatory T cell
Gene: Fgf23 (fibroblast growth factor 23) Type: protein-coding Summary: This gene encodes a member of the fibroblast growth factor family. The encoded protein regulates phosphate homeostasis and vitamin D metabolism. Mutation of the related gene in humans causes autosomal dominant hypophosphatemic ricke...
Does Knockout of Il5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Il5
cell proliferation
Mouse kidney carcinoma cell
Gene: Il5 (interleukin 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytokine-mediated signaling pathway, eosinophil differentiation, immune response, interleukin-5-mediated signaling pathway, positive regulation of B cell proliferation, positive regulation of cell p...
Does Knockout of Irx2 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Irx2
phagocytosis
macrophage
Gene: Irx2 (Iroquois homeobox 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ development, cell development, metanephros development, negative regulation of transcription by RNA polymerase II, neuron differentiation, proximal/distal pattern formation invol...
Does Knockout of Zfp954 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Zfp954
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Zfp954 (zinc finger protein 954) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Oscp1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Oscp1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Oscp1 (organic solute carrier partner 1) Type: protein-coding Summary: Predicted to enable transmembrane transporter activity. Predicted to be involved in xenobiotic detoxification by transmembrane export across the plasma membrane. Located in cytoplasm. Is expressed in several structures, includi...
Does Knockout of Prdx6 in myoblast cell line causally result in protein/peptide distribution?
1
1,680
Knockout
Prdx6
protein/peptide distribution
myoblast cell line
Gene: Prdx6 (peroxiredoxin 6) Type: protein-coding Summary: This gene encodes a member of the peroxiredoxin family of peroxidases. The encoded protein is a bifunctional enzyme that has glutathione peroxidase and phospholipase activities. This protein is an antioxidant that reduces peroxidized membrane p...
Does Knockout of Kif21a in cardiac muscle cell line causally result in protein/peptide accumulation?
0
1,662
Knockout
Kif21a
protein/peptide accumulation
cardiac muscle cell line
Gene: Kif21a (kinesin family member 21A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterograde axonal transport, cortical microtubule organization, microtubule-based movement, regulation of axon guidance, regulation of microtubule depolymerization, regulation of mic...
Does Knockout of Ugcg in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Ugcg
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ugcg (UDP-glucose ceramide glucosyltransferase) Type: protein-coding Summary: Enables ceramide glucosyltransferase activity. Involved in several processes, including cornified envelope assembly; establishment of skin barrier; and glucosylceramide biosynthetic process. Predicted to be located in Go...
Does Knockout of Amdhd2 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Amdhd2
protein/peptide distribution
myoblast cell line
Gene: Amdhd2 (amidohydrolase domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: N-acetylglucosamine catabolic process, N-acetylglucosamine metabolic process, N-acetylneuraminate catabolic process, negative regulation of UDP-N-acetylglucosamine biosynthet...