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string
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Does Knockout of Chd1l in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
84
Knockout
Chd1l
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Chd1l (chromodomain helicase DNA binding protein 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA repair, chromatin remodeling; MF: ATP binding, ATP hydrolysis activity, ATP-dependent chromatin remodeler activity, DNA helicase activit...
Does Knockout of Defa24 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Defa24
protein/peptide accumulation
Mouse cell
Gene: Defa24 (defensin, alpha, 24) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antibacterial humoral response, antimicrobial humoral immune response mediated by antimicrobial peptide, defense response, defense response to Gram-negative bacterium, defense response to G...
Does Knockout of Eef1a2 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Eef1a2
protein/peptide accumulation
Embryonic Cell Line
Gene: Eef1a2 (eukaryotic translation elongation factor 1 alpha 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of apoptotic process, regulation of postsynaptic specialization assembly, translation, translational elongation; MF: GTP binding, GTPase a...
Does Knockout of Sf3b6 in Cytotoxic T-lymphocyte (CD8+ T cells) causally result in cell proliferation?
1
2,412
Knockout
Sf3b6
cell proliferation
Cytotoxic T-lymphocyte (CD8+ T cells)
Gene: Sf3b6 (splicing factor 3B, subunit 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, blastocyst formation, mRNA processing, mRNA splicing, via spliceosome; MF: RNA binding, mRNA binding, nucleic acid binding; CC: U12-type spliceosomal complex, U2-type...
Does Knockout of Krt14 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Krt14
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Krt14 (keratin 14) Type: protein-coding Summary: This gene encodes a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cyt...
Does Knockout of Tmem25 in myoblast cell line causally result in protein/peptide distribution?
0
1,685
Knockout
Tmem25
protein/peptide distribution
myoblast cell line
Gene: Tmem25 (transmembrane protein 25) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of excitatory postsynaptic potential, regulation of protein stability; CC: endosome, extracellular region, late endosome, lysosome, membrane, plasma membrane ...
Does Knockout of Grsf1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Grsf1
cell proliferation
Mouse kidney carcinoma cell
Gene: Grsf1 (G-rich RNA sequence binding factor 1) Type: protein-coding Summary: Predicted to enable RNA binding activity. Acts upstream of or within anterior/posterior pattern specification and morphogenesis of embryonic epithelium. Located in mitochondrion. Is expressed in several structures, includin...
Does Knockout of Miga1 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Miga1
cell cycle progression
breast epithelium
Gene: Miga1 (mitoguardin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mitochondrial fusion; MF: protein heterodimerization activity, protein homodimerization activity; CC: membrane, mitochondrial outer membrane, mitochondrion, plasma membrane Pathways: Glyc...
Does Knockout of Pnck in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,175
Knockout
Pnck
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Pnck (pregnancy upregulated non-ubiquitously expressed CaM kinase) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, calcium/calmodulin-dependent protein kinase activity, calmodulin binding, kinase activity, nucleotide binding, protein kinase activity, pr...
Does Knockout of Gm4567 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Gm4567
phagocytosis
macrophage
Gene: Gm4567 (predicted gene 4567) Type: protein-coding Summary: No summary available. Gene Ontology: MF: ATP binding, kinase activity, molecular_function, nucleotide binding, protein kinase activity, protein serine/threonine kinase activity, transferase activity Pathways: Un...
Does Knockout of Pex7 in Melanoma Cell Line causally result in cell proliferation?
0
1,281
Knockout
Pex7
cell proliferation
Melanoma Cell Line
Gene: Pex7 (peroxisomal biogenesis factor 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: endochondral ossification, ether lipid biosynthetic process, fatty acid beta-oxidation, neuron migration, peroxisome organization, protein import into peroxisome matrix, protein t...
Does Knockout of Serpina1d in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Serpina1d
cell proliferation
Mouse kidney carcinoma cell
Gene: Serpina1d (serine (or cysteine) peptidase inhibitor, clade A, member 1D) Type: protein-coding Summary: No summary available. Gene Ontology: BP: response to chromate, response to cytokine, response to lead ion, response to methanol, response to peptide hormone; MF: endopeptidase inhibitor ...
Does Knockout of Arhgef37 in renal medulla cell line causally result in response to bacteria?
0
2,049
Knockout
Arhgef37
response to bacteria
renal medulla cell line
Gene: Arhgef37 (Rho guanine nucleotide exchange factor 37) Type: protein-coding Summary: No summary available. Gene Ontology: MF: guanyl-nucleotide exchange factor activity; CC: cellular_component, cytoplasm Pathways: Cell death signalling via NRAGE, NRIF and NADE, Death Receptor Signa...
Does Knockout of Dnajb11 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Dnajb11
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Dnajb11 (DnaJ heat shock protein family (Hsp40) member B11) Type: protein-coding Summary: No summary available. Gene Ontology: BP: mRNA modification, negative regulation of neurogenesis, protein folding, protein maturation; MF: misfolded protein binding, protein binding, signaling recepto...
Does Knockout of Klhl10 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,266
Knockout
Klhl10
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Klhl10 (kelch-like 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cell morphogenesis, fertilization, homeostasis of number of cells within a tissue, male genitalia morphogenesis, male gonad development, proteasome-mediated ubiquitin-depend...
Does Knockout of Zfp775 in Regulatory T cell causally result in cell proliferation?
0
1,483
Knockout
Zfp775
cell proliferation
Regulatory T cell
Gene: Zfp775 (zinc finger protein 775) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding, metal ion binding, zinc ion bi...
Does Knockout of Abi2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Abi2
cell proliferation
Mouse kidney carcinoma cell
Gene: Abi2 (abl interactor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Rac protein signal transduction, camera-type eye development, cell migration, cell projection morphogenesis, dendrite development, learning or memory, lens fiber cell morphogenesis, mitophagy, n...
Does Knockout of Rnf185 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Rnf185
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Rnf185 (ring finger protein 185) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, autophagy, cGAS/STING signaling pathway, defense response to virus, immune system process, innate immune response, positive regulation of ERAD pathway, positive regulation...
Does Knockout of Nr1i2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Nr1i2
cell proliferation
Mouse kidney carcinoma cell
Gene: Nr1i2 (nuclear receptor subfamily 1, group I, member 2) Type: protein-coding Summary: Enables nuclear receptor activity. Involved in cellular response to molecule of bacterial origin. Acts upstream of or within gene expression and positive regulation of gene expression. Located in nucleus. Part of...
Does Knockout of Peg3 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Peg3
cell proliferation
Embryonic Stem Cell Line
Gene: Peg3 (paternally expressed 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, negative regulation of transcription by RNA polymerase II, positive regulation of transcription by RNA polymerase II, regulation of gene expression, regulation of transc...
Does Knockout of Try5 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Try5
cell proliferation
Colonic Cancer Cell Line
Gene: Try5 (trypsin 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteolysis; MF: calcium ion binding, hydrolase activity, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity; CC: acrosomal vesicle, cytoplasmic vesicle, extracellul...
Does Knockout of Mesd in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Mesd
cell proliferation
Mouse kidney carcinoma cell
Gene: Mesd (mesoderm development LRP chaperone) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Wnt signaling pathway, mesoderm development, negative regulation of protein glycosylation, ossification, phagocytosis, positive regulation of Wnt signaling pathway, positive re...
Does Knockout of Pkig in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,398
Knockout
Pkig
protein/peptide accumulation
Microglial Cell Line
Gene: Pkig (protein kinase inhibitor, gamma) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of protein import into nucleus, negative regulation of transcription by RNA polymerase II; MF: cAMP-dependent protein kinase inhibitor activity, protein kinase...
Does Knockout of Pdha2 in Embryonic Fibroblast Cell Line causally result in cell proliferation?
0
345
Knockout
Pdha2
cell proliferation
Embryonic Fibroblast Cell Line
Gene: Pdha2 (pyruvate dehydrogenase E1 alpha 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: glucose metabolic process, pyruvate decarboxylation to acetyl-CoA, tricarboxylic acid cycle; MF: metal ion binding, oxidoreductase activity, oxidoreductase activity, acting on ...
Does Knockout of Gm10392 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Gm10392
cell proliferation
Mouse kidney carcinoma cell
Gene: Gm10392 (predicted gene 10392) Type: ncRNA Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 100049168
Does Knockout of Cyp2j12 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Cyp2j12
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Cyp2j12 (cytochrome P450, family 2, subfamily j, polypeptide 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: epoxygenase P450 pathway, icosanoid metabolic process, linoleic acid metabolic process, organic acid metabolic process, xenobiotic metabolic process; MF:...
Does Knockout of Gpr89 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Gpr89
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Gpr89 (G protein-coupled receptor 89) Type: protein-coding Summary: Predicted to enable voltage-gated monoatomic anion channel activity. Involved in T cell differentiation. Acts upstream of or within skin development. Predicted to be located in Golgi-associated vesicle membrane. Predicted to be pa...
Does Knockout of Slc6a14 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,178
Knockout
Slc6a14
tumorigenicity
Colonic Cancer Cell Line
Gene: Slc6a14 (solute carrier family 6 (neurotransmitter transporter), member 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: (R)-carnitine transmembrane transport, alanine transport, amine transport, amino acid import across plasma membrane, amino acid transport, bet...
Does Knockout of Zyg11a in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Zyg11a
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Zyg11a (zyg-11 family member A, cell cycle regulator) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A0A1Y7VNL1, A0A217FL76, F8WHU3 Entrez ID: 230590
Does Knockout of Vav1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
1,664
Knockout
Vav1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Vav1 (vav 1 oncogene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell proliferation, G protein-coupled receptor signaling pathway, T cell activation, T cell costimulation, T cell differentiation, cell migration, cell surface receptor signaling pathway, immune...
Does Knockout of Nmrk2 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Nmrk2
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nmrk2 (nicotinamide riboside kinase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: NAD+ biosynthetic process, NAD+ biosynthetic process via the salvage pathway, NADP+ biosynthetic process, negative regulation of myoblast differentiation, nicotinamide riboside me...
Does Knockout of Eddm3b in Regulatory T cell causally result in cell proliferation?
0
2,127
Knockout
Eddm3b
cell proliferation
Regulatory T cell
Gene: Eddm3b (epididymal protein 3B) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8K0E4 Entrez ID: 219026
Does Knockout of Grip1 in Melanoma Cell Line causally result in cell proliferation?
0
2,488
Knockout
Grip1
cell proliferation
Melanoma Cell Line
Gene: Grip1 (glutamate receptor interacting protein 1) Type: protein-coding Summary: This gene encodes a protein containing multiple PDZ (post synaptic density protein, Drosophila disc large tumor suppressor, and zonula occludens-1 protein) domains. The encoded protein acts as a mediator between cytoske...
Does Knockout of Tcf24 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,265
Knockout
Tcf24
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Tcf24 (transcription factor 24) Type: protein-coding Summary: No summary available. Gene Ontology: BP: developmental process, regulation of transcription by RNA polymerase II; MF: DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II transcription regula...
Does Knockout of Ints8 in Embryonic Stem Cell Line causally result in cell proliferation?
1
2,477
Knockout
Ints8
cell proliferation
Embryonic Stem Cell Line
Gene: Ints8 (integrator complex subunit 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II transcription initiation surveillance, protein localization to chromatin, snRNA 3'-end processing, snRNA processing; CC: INTAC complex, chromatin, chromosome, inte...
Does Knockout of Tmem139 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Tmem139
phagocytosis
macrophage
Gene: Tmem139 (transmembrane protein 139) Type: protein-coding Summary: No summary available. Gene Ontology: CC: cellular_component, membrane Pathways: UniProt: E9PX92, Q8C6T0 Entrez ID: 109218
Does Knockout of Plcxd2 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Plcxd2
protein/peptide distribution
myoblast cell line
Gene: Plcxd2 (phosphatidylinositol-specific phospholipase C, X domain containing 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, lipid catabolic process, lipid metabolic process, signal transduction; MF: hydrolase activity, molecular_function, phosp...
Does Knockout of Pnpla8 in Melanoma Cell Line causally result in cell proliferation?
0
1,838
Knockout
Pnpla8
cell proliferation
Melanoma Cell Line
Gene: Pnpla8 (patatin-like phospholipase domain containing 8) Type: protein-coding Summary: Enables calcium-independent phospholipase A2 activity. Involved in cardiolipin metabolic process; regulation of cellular response to oxidative stress; and triglyceride homeostasis. Located in mitochondrion and pe...
Does Knockout of Rps27rt in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Rps27rt
cell cycle progression
breast epithelium
Gene: Rps27rt (ribosomal protein S27, retrogene) Type: protein-coding Summary: Predicted to be a structural constituent of ribosome. Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to be located in cytosolic ribosome and nucleus. Predicted to be part of cyto...
Does Knockout of Sec14l2 in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Sec14l2
cell proliferation
Melanoma Cell Line
Gene: Sec14l2 (SEC14-like lipid binding 2) Type: protein-coding Summary: No summary available. Gene Ontology: MF: enzyme activator activity, lipid binding, transferase activity, transferring alkyl or aryl (other than methyl) groups; CC: cytoplasm, cytosol, nucleoplasm, nucleus Pathways...
Does Knockout of Zfand3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Zfand3
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfand3 (zinc finger, AN1-type domain 3) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA binding, metal ion binding, molecular_function, zinc ion binding Pathways: UniProt: Q497H0 Entrez ID: 21769
Does Knockout of Rps3a1 in Acute Myeloid Leukemia Cell Line causally result in cell proliferation?
1
684
Knockout
Rps3a1
cell proliferation
Acute Myeloid Leukemia Cell Line
Gene: Rps3a1 (ribosomal protein S3A1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, cytoplasmic translation, negative regulation of apoptotic process, ribosomal small subunit biogenesis, translation; MF: mRNA 5'-UTR binding, mRNA binding, protein b...
Does Knockout of Cadm2 in Melanoma Cell Line causally result in protein/peptide accumulation?
1
1,839
Knockout
Cadm2
protein/peptide accumulation
Melanoma Cell Line
Gene: Cadm2 (cell adhesion molecule 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell adhesion, homophilic cell adhesion via plasma membrane adhesion molecules, synaptic membrane adhesion; CC: GABA-ergic synapse, axon, cell projection, glutamatergic synapse, membran...
Does Knockout of Pafah2 in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Pafah2
protein/peptide distribution
myoblast cell line
Gene: Pafah2 (platelet-activating factor acetylhydrolase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: lipid catabolic process, lipid metabolic process, negative regulation of apoptotic process; MF: 1-alkyl-2-acetylglycerophosphocholine esterase activity, hydrolase a...
Does Knockout of Serpinb3d in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,268
Knockout
Serpinb3d
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Serpinb3d (serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3D) Type: protein-coding Summary: No summary available. Gene Ontology: MF: cysteine-type endopeptidase inhibitor activity, endopeptidase inhibitor activity, enzyme binding, peptidase inhibitor activity, prote...
Does Knockout of Tnnc1 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Tnnc1
phagocytosis
macrophage
Gene: Tnnc1 (troponin C, cardiac/slow skeletal) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cardiac muscle cell contraction, cardiac muscle contraction, diaphragm contraction, muscle filament sliding, regulation of muscle contraction, regulation of muscle filament sli...
Does Knockout of Cela3a in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,260
Knockout
Cela3a
cell proliferation
Mouse kidney carcinoma cell
Gene: Cela3a (chymotrypsin-like elastase family, member 3A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteolysis; MF: hydrolase activity, peptidase activity, serine-type endopeptidase activity, serine-type peptidase activity Pathways: Pancreatic secretion ...
Does Knockout of Erf in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
1,664
Knockout
Erf
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Erf (Ets2 repressor factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, chorio-allantoic fusion, ectodermal cell differentiation, in utero embryonic development, regulation of DNA-templated transcription, regulation of transcription by RNA ...
Does Knockout of Aff1 in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Aff1
cell cycle progression
breast epithelium
Gene: Aff1 (AF4/FMR2 family, member 1) Type: protein-coding Summary: This gene encodes a member of the AF4/ lymphoid nuclear protein related to the Fragile X E syndrome (FRAXE) family of proteins, which have been implicated in human childhood lymphoblastic leukemia, fragile chromosome X intellectual dis...
Does Knockout of Hikeshi in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Hikeshi
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Hikeshi (heat shock protein nuclear import factor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Golgi organization, cellular response to heat, lung development, protein import into nucleus, protein transport; MF: Hsp70 protein binding, nuclear import signal recep...
Does Knockout of Gm10941 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Gm10941
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Gm10941 (predicted gene 10941) Type: ncRNA Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID: 100169878
Does Knockout of Las1l in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Las1l
cell proliferation
Colonic Cancer Cell Line
Gene: Las1l (LAS1-like (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: maturation of 5.8S rRNA, maturation of LSU-rRNA, rRNA processing; MF: endonuclease activity, hydrolase activity; CC: Las1 complex, MLL1 complex, cytoplasm, nucleolus, nucleoplasm, nucl...
Does Knockout of Hoxd3 in Embryonic Stem Cell Line causally result in cell proliferation?
0
579
Knockout
Hoxd3
cell proliferation
Embryonic Stem Cell Line
Gene: Hoxd3 (homeobox D3) Type: protein-coding Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including glossopharyngea...
Does Knockout of Rsrp1 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Rsrp1
phagocytosis
macrophage
Gene: Rsrp1 (arginine/serine rich protein 1) Type: protein-coding Summary: Predicted to be involved in spliceosomal complex assembly. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; extraembryonic component; and retina. Orthologous to human RSRP1...
Does Knockout of Ankrd66 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Ankrd66
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Ankrd66 (ankyrin repeat domain 66) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, positive regulation of canonical Wnt signaling pathway, positive regulation of telomere capping, protein localization to chromosome, telomeric region; MF: NAD+ pol...
Does Knockout of Cpne3 in Melanoma Cell Line causally result in cell proliferation?
0
1,281
Knockout
Cpne3
cell proliferation
Melanoma Cell Line
Gene: Cpne3 (copine III) Type: protein-coding Summary: Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encodes a calcium-dependent protein containing two N-terminal type II C2 domains an...
Does Knockout of Star in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Star
protein/peptide accumulation
Regulatory T cell
Gene: Star (steroidogenic acute regulatory protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: bile acid biosynthetic process, biphenyl metabolic process, cellular response to alkaloid, cellular response to antibiotic, cellular response to cAMP, cellular response to ...
Does Knockout of Ttbk1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Ttbk1
cell proliferation
Mouse kidney carcinoma cell
Gene: Ttbk1 (tau tubulin kinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: learning or memory, negative regulation of gene expression, positive regulation of astrocyte activation, positive regulation of gene expression, positive regulation of microglial cell activ...
Does Knockout of 4930453N24Rik in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,152
Knockout
4930453N24Rik
protein/peptide accumulation
Embryonic Cell Line
Gene: 4930453N24Rik (RIKEN cDNA 4930453N24 gene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, positive regulation of apoptotic process; CC: nucleus Pathways: UniProt: Q3TTL0 Entrez ID: 67609
Does Knockout of Chit1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,259
Knockout
Chit1
cell proliferation
Mouse kidney carcinoma cell
Gene: Chit1 (chitinase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate metabolic process, chitin catabolic process, polysaccharide catabolic process; MF: chitin binding, chitinase activity, endochitinase activity, hydrolase activity, hydrolase activity, ac...
Does Knockout of Nxf1 in myoblast cell line causally result in protein/peptide distribution?
1
1,684
Knockout
Nxf1
protein/peptide distribution
myoblast cell line
Gene: Nxf1 (nuclear RNA export factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA export from nucleus, mRNA export from nucleus, mRNA transport, poly(A)+ mRNA export from nucleus, protein transport; MF: RNA binding, mRNA binding, nucleic acid binding, protein b...
Does Knockout of Lgals12 in Mouse Embryonic Stem Cell causally result in protein/peptide accumulation?
0
1,077
Knockout
Lgals12
protein/peptide accumulation
Mouse Embryonic Stem Cell
Gene: Lgals12 (lectin, galactose binding, soluble 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, intrinsic apoptotic signaling pathway; MF: carbohydrate binding, lactose binding; CC: cytoplasm, mitochondrion, nucleus Pathways: Un...
Does Knockout of Ropn1 in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Ropn1
cell proliferation
Melanoma Cell Line
Gene: Ropn1 (ropporin, rhophilin associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cilium organization, flagellated sperm motility, protein localization to cilium, sperm capacitation; MF: identical protein binding, protein binding, protein heterodimeri...
Does Knockout of Nucb1 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,263
Knockout
Nucb1
cell proliferation
Colonic Cancer Cell Line
Gene: Nucb1 (nucleobindin 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of protein targeting, small GTPase-mediated signal transduction; MF: DNA binding, G-protein alpha-subunit binding, calcium ion binding, guanyl-nucleotide exchange factor activity, meta...
Does Knockout of Rab27b in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Rab27b
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Rab27b (RAB27B, member RAS oncogene family) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anterograde axonal protein transport, exocytosis, multivesicular body sorting pathway, positive regulation of exocytosis, regulation of exocytosis, synaptic vesicle endocytos...
Does Knockout of Kcnj14 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Kcnj14
cell proliferation
Mouse kidney carcinoma cell
Gene: Kcnj14 (potassium inwardly-rectifying channel, subfamily J, member 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion import across plasma membrane, potassium ion transport, regulation ...
Does Knockout of Adnp2 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Adnp2
protein/peptide distribution
myoblast cell line
Gene: Adnp2 (ADNP homeobox 2) Type: protein-coding Summary: Predicted to enable DNA binding activity and zinc ion binding activity. Involved in nervous system development. Predicted to be active in nucleus. Is expressed in several structures, including blastocyst; brain; genitourinary system; pancreas; ...
Does Knockout of Ccdc152 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Ccdc152
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Ccdc152 (coiled-coil domain containing 152) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: A0A2I3BPP3, E9PX14 Entrez ID: 100039139
Does Knockout of Cyp2a12 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Cyp2a12
cell proliferation
Colonic Cancer Cell Line
Gene: Cyp2a12 (cytochrome P450, family 2, subfamily a, polypeptide 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: coumarin metabolic process, epoxygenase P450 pathway, xenobiotic metabolic process; MF: arachidonate epoxygenase activity, coumarin 7-hydroxylase activit...
Does Knockout of Epha7 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Epha7
cell proliferation
Melanoma Cell Line
Gene: Epha7 (Eph receptor A7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, axon guidance, brain development, branching morphogenesis of a nerve, cell surface receptor protein tyrosine kinase signaling pathway, central nervous system development, ephr...
Does Knockout of Cbln1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,289
Knockout
Cbln1
cell proliferation
Mouse kidney carcinoma cell
Gene: Cbln1 (cerebellin 1 precursor protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cerebellar granule cell differentiation, establishment of localization in cell, heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules, maintenance of synapse...
Does Knockout of Sun5 in Melanoma Cell Line causally result in cell proliferation?
0
1,281
Knockout
Sun5
cell proliferation
Melanoma Cell Line
Gene: Sun5 (Sad1 and UNC84 domain containing 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, protein-containing complex assembly, regulation of protein localization, spermatid development, spermatogenesis; MF: protein binding, protein-membrane ada...
Does Knockout of Adh6a in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,264
Knockout
Adh6a
cell proliferation
Colonic Cancer Cell Line
Gene: Adh6a (alcohol dehydrogenase 6A (class V)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: retinoic acid metabolic process, retinol metabolic process, small molecule catabolic process; MF: alcohol dehydrogenase (NAD+) activity, all-trans-retinol dehydrogenase (NAD+)...
Does Knockout of Gm5142 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Gm5142
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Gm5142 (predicted gene 5142) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8C5X9 Entrez ID: 380907
Does Knockout of Traf2 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Traf2
protein/peptide accumulation
Regulatory T cell
Gene: Traf2 (TNF receptor-associated factor 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: CD27 signaling pathway, CD40 signaling pathway, T cell activation, TORC1 complex assembly, TORC1 signaling, TORC2 complex disassembly, TORC2 signaling, apoptotic process, cellul...
Does Knockout of Ppat in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Ppat
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ppat (phosphoribosyl pyrophosphate amidotransferase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 'de novo' AMP biosynthetic process, 'de novo' IMP biosynthetic process, 'de novo' XMP biosynthetic process, GMP biosynthetic process, L-glutamine catabolic process, ...
Does Knockout of Zcchc7 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,261
Knockout
Zcchc7
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Zcchc7 (zinc finger, CCHC domain containing 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: TRAMP-dependent tRNA surveillance pathway, biological_process, nuclear mRNA surveillance of mRNA 3'-end processing, nuclear polyadenylation-dependent CUT catabolic process...
Does Knockout of Apex2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Apex2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Apex2 (apurinic/apyrimidinic endonuclease 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, DNA recombination, DNA repair, base-excision repair; MF: DNA binding, DNA-(apurinic or apyrimidinic site) endonuclease activity, catalytic activity, dou...
Does Knockout of Ifi209 in Melanoma Cell Line causally result in cell proliferation?
0
1,269
Knockout
Ifi209
cell proliferation
Melanoma Cell Line
Gene: Ifi209 (interferon activated gene 209) Type: protein-coding Summary: Predicted to enable double-stranded DNA binding activity and identical protein binding activity. Acts upstream of or within cellular response to interferon-beta. Predicted to be located in nucleolus. Predicted to be active in cyt...
Does Knockout of Akr1c20 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,262
Knockout
Akr1c20
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Akr1c20 (aldo-keto reductase family 1, member C20) Type: protein-coding Summary: No summary available. Gene Ontology: BP: daunorubicin metabolic process, doxorubicin metabolic process, progesterone metabolic process, prostaglandin metabolic process, response to estrogen, response to xenob...
Does Knockout of Ccdc61 in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Ccdc61
protein/peptide accumulation
Regulatory T cell
Gene: Ccdc61 (coiled-coil domain containing 61) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, centriole assembly, mitotic spindle assembly; MF: identical protein binding, microtubule binding; CC: cell projection, centriolar satellite, centr...
Does Knockout of Kcnh5 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,170
Knockout
Kcnh5
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Kcnh5 (potassium voltage-gated channel, subfamily H (eag-related), member 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion transmembrane transport, potassium ion transport, regulation ...
Does Knockout of Mir2137 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
688
Knockout
Mir2137
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Mir2137 (microRNA 2137) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Zbtb37 in Immortal mouse chromaffin cells causally result in cell viability?
0
2,469
Knockout
Zbtb37
cell viability
Immortal mouse chromaffin cells
Gene: Zbtb37 (zinc finger and BTB domain containing 37) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, regulation of cytokine production, regulation of immune system process; MF: DNA binding, DNA-binding transcri...
Does Knockout of Ankar in Regulatory T cell causally result in protein/peptide accumulation?
0
1,481
Knockout
Ankar
protein/peptide accumulation
Regulatory T cell
Gene: Ankar (ankyrin and armadillo repeat containing) Type: protein-coding Summary: Predicted to be located in membrane. Orthologous to human ANKAR (ankyrin and armadillo repeat containing). [provided by Alliance of Genome Resources, Jul 2025] Gene Ontology: Pathways: UniPro...
Does Knockout of Dyrk3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Dyrk3
cell proliferation
Mouse kidney carcinoma cell
Gene: Dyrk3 (dual-specificity tyrosine phosphorylation regulated kinase 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, erythrocyte differentiation, negative regulation of DNA damage response, signal transduction by p53 class mediator, negative regulatio...
Does Knockout of Kcnh1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,288
Knockout
Kcnh1
cell proliferation
Mouse kidney carcinoma cell
Gene: Kcnh1 (potassium voltage-gated channel, subfamily H (eag-related), member 1) Type: protein-coding Summary: Enables delayed rectifier potassium channel activity and voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential. Involved in potassium ion tran...
Does Knockout of Gm1995 in Melanoma Cell Line causally result in cell proliferation?
0
2,492
Knockout
Gm1995
cell proliferation
Melanoma Cell Line
Gene: Gm1995 (predicted gene 1995) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Galnt12 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
1,130
Knockout
Galnt12
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Galnt12 (polypeptide N-acetylgalactosaminyltransferase 12) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, protein O-linked glycosylation, protein O-linked glycosylation via N-acetyl-galactosamine, protein glycosylation; MF: carbohydrate binding,...
Does Knockout of Prl8a2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Prl8a2
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Prl8a2 (prolactin family 8, subfamily a, member 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell surface receptor signaling pathway, female pregnancy, mammary gland development, maternal process involved in female pregnancy, positive regulation of lactation, ...
Does Knockout of S100pbp in Cytotoxic T-lymphocyte (CD8+ T cells) causally result in cell proliferation?
1
2,411
Knockout
S100pbp
cell proliferation
Cytotoxic T-lymphocyte (CD8+ T cells)
Gene: S100pbp (S100P binding protein) Type: protein-coding Summary: No summary available. Gene Ontology: MF: calcium-dependent protein binding, molecular_function; CC: cytosol, nuclear speck, nucleus Pathways: UniProt: Q9D5K4 Entrez ID: 74648
Does Knockout of Snf8 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,290
Knockout
Snf8
cell proliferation
Mouse kidney carcinoma cell
Gene: Snf8 (SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: early endosome to late endosome transport, endocytic recycling, macroautophagy, multivesicular body assembly, multivesicular body sorting pathway, positive...
Does Knockout of Igf1r in myoblast cell line causally result in protein/peptide distribution?
0
1,680
Knockout
Igf1r
protein/peptide distribution
myoblast cell line
Gene: Igf1r (insulin-like growth factor I receptor) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adrenal gland development, amyloid-beta clearance, animal organ morphogenesis, axonogenesis, brain development, cell surface receptor protein tyrosine kinase signaling path...
Does Knockout of Psma2 in Melanoma Cell Line causally result in protein/peptide accumulation?
0
1,839
Knockout
Psma2
protein/peptide accumulation
Melanoma Cell Line
Gene: Psma2 (proteasome subunit alpha 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: proteasome-mediated ubiquitin-dependent protein catabolic process, proteolysis involved in protein catabolic process, response to virus, ubiquitin-dependent protein catabolic process;...
Does Knockout of Vmn1r86 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Vmn1r86
cell proliferation
Melanoma Cell Line
Gene: Vmn1r86 (vomeronasal 1 receptor 86) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromone ...
Does Knockout of Brwd3 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,178
Knockout
Brwd3
tumorigenicity
Colonic Cancer Cell Line
Gene: Brwd3 (bromodomain and WD repeat domain containing 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cytoskeleton organization, regulation of cell shape, regulation of transcription by RNA polymerase II Pathways: UniProt: A2AHJ4 Entrez ID...
Does Knockout of Ech1 in pro-B-lymphocyte causally result in response to chemicals?
0
1,720
Knockout
Ech1
response to chemicals
pro-B-lymphocyte
Gene: Ech1 (enoyl coenzyme A hydratase 1, peroxisomal) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid beta-oxidation, fatty acid metabolic process, lipid metabolic process; MF: catalytic activity, delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity, isomerase...
Does Knockout of Mir219b in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Mir219b
cell cycle progression
breast epithelium
Gene: Mir219b (microRNA 219b) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase...
Does Knockout of Tsku in Microglial Cell Line causally result in response to virus?
0
2,429
Knockout
Tsku
response to virus
Microglial Cell Line
Gene: Tsku (tsukushi, small leucine rich proteoglycan) Type: protein-coding Summary: No summary available. Gene Ontology: BP: anatomical structure morphogenesis, anterior commissure morphogenesis, camera-type eye development, cholesterol efflux, cholesterol homeostasis, cholesterol metabolic pr...
Does Knockout of Atp6v0d2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
1,664
Knockout
Atp6v0d2
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Atp6v0d2 (ATPase, H+ transporting, lysosomal V0 subunit D2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: monoatomic ion transport, proton transmembrane transport, vacuolar acidification, vacuolar transport; CC: apical plasma membrane, early endosome, endosome, me...