prompt string | hit int64 | screen_id int64 | crispr_strategy string | gene string | phenotype string | cell_type string | gene_context string |
|---|---|---|---|---|---|---|---|
Does Knockout of Zp1 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,679 | Knockout | Zp1 | protein/peptide distribution | myoblast cell line | Gene: Zp1 (zona pellucida glycoprotein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: binding of sperm to zona pellucida, prevention of polyspermy, single fertilization; MF: acrosin binding, structural constituent of egg coat; CC: egg coat, extracellular matrix, extra... |
Does Knockout of Slc35e4 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,274 | Knockout | Slc35e4 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Slc35e4 (solute carrier family 35, member E4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: Golgi apparatus, membrane
Pathways:
UniProt: Q8K3D6
Entrez ID: 103710 |
Does Knockout of Myf6 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,274 | Knockout | Myf6 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Myf6 (myogenic factor 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell differentiation, muscle organ development, muscle tissue morphogenesis, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription, positive reg... |
Does Knockout of Serpina3g in Pancreatic Cancer Cell Line causally result in response to chemicals? | 0 | 2,359 | Knockout | Serpina3g | response to chemicals | Pancreatic Cancer Cell Line | Gene: Serpina3g (serine (or cysteine) peptidase inhibitor, clade A, member 3G)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: adaptive immune response, apoptotic process, immune system process, response to cytokine, response to peptide hormone; MF: cysteine-type endopept... |
Does Knockout of Ly6a in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 163 | Knockout | Ly6a | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Ly6a (lymphocyte antigen 6 family member A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: acetylcholine receptor signaling pathway, response to bacterium; MF: acetylcholine receptor binding, acetylcholine receptor inhibitor activity, protein binding; CC: external ... |
Does Knockout of Fndc11 in Regulatory T cell causally result in protein/peptide accumulation? | 0 | 1,482 | Knockout | Fndc11 | protein/peptide accumulation | Regulatory T cell | Gene: Fndc11 (fibronectin type III domain containing 11)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q80WB0
Entrez ID: 332713 |
Does Knockout of Bora in Melanoma Cell Line causally result in cell proliferation? | 0 | 2,492 | Knockout | Bora | cell proliferation | Melanoma Cell Line | Gene: Bora (bora, aurora kinase A activator)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell division, regulation of mitotic nuclear division, regulation of mitotic spindle organization, regulation of protein localization; MF: protein kinase binding; CC: cytoplasm, m... |
Does Knockout of Slc39a4 in macrophage causally result in phagocytosis? | 0 | 1,888 | Knockout | Slc39a4 | phagocytosis | macrophage | Gene: Slc39a4 (solute carrier family 39 (zinc transporter), member 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: bicarbonate transport, cellular response to zinc ion starvation, intracellular monoatomic cation homeostasis, intracellular zinc ion homeostasis, metal io... |
Does Knockout of Oprl1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 161 | Knockout | Oprl1 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Oprl1 (opioid receptor-like 1)
Type: protein-coding
Summary: The protein encoded by this gene is a member of the 7 transmembrane-spanning G protein-coupled receptor family, and functions as a receptor for the endogenous, opioid-related neuropeptide, nociceptin/orphanin FQ. This receptor-ligand sys... |
Does Knockout of Epn3 in Regulatory T cell causally result in protein/peptide accumulation? | 0 | 1,482 | Knockout | Epn3 | protein/peptide accumulation | Regulatory T cell | Gene: Epn3 (epsin 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: EH domain binding, clathrin binding, lipid binding, phospholipid binding; CC: cell cortex, clathrin vesicle coat, clathrin-coated pit, clathrin-coated vesicle, cytoplasm, cytoplasmic side of plasma membr... |
Does Knockout of Astn1 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 163 | Knockout | Astn1 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Astn1 (astrotactin 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell adhesion, cell migration, cell-cell adhesion, locomotory behavior, neuron cell-cell adhesion, neuron migration; CC: clathrin-coated vesicle, cytoplasmic vesicle, endosome, external side of pl... |
Does Knockout of Clic5 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 687 | Knockout | Clic5 | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Clic5 (chloride intracellular channel 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: auditory receptor cell stereocilium organization, chloride transmembrane transport, chloride transport, diet induced thermogenesis, epidermal cell differentiation, inner ear rec... |
Does Knockout of Mgst3 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,272 | Knockout | Mgst3 | cell proliferation | Mouse kidney carcinoma cell | Gene: Mgst3 (microsomal glutathione S-transferase 3)
Type: protein-coding
Summary: Predicted to enable several functions, including glutathione peroxidase activity; glutathione transferase activity; and leukotriene-C4 synthase activity. Predicted to be involved in leukotriene biosynthetic process and pr... |
Does Knockout of Nlrp4g in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,266 | Knockout | Nlrp4g | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Nlrp4g (NLR family, pyrin domain containing 4G)
Type:
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt:
Entrez ID: |
Does Knockout of Foxd3 in Mouse cell causally result in protein/peptide accumulation? | 0 | 1,047 | Knockout | Foxd3 | protein/peptide accumulation | Mouse cell | Gene: Foxd3 (forkhead box D3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA-templated transcription, anatomical structure morphogenesis, cell differentiation, cellular response to leukemia inhibitory factor, embryonic placenta development, in utero embryonic develop... |
Does Knockout of Birc7 in breast epithelium causally result in cell cycle progression? | 0 | 1,469 | Knockout | Birc7 | cell cycle progression | breast epithelium | Gene: Birc7 (baculoviral IAP repeat-containing 7)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, lens development in camera-type eye, negative regulation of apoptotic process, negative regulation of tumor necrosis factor-mediated signaling pathway, pos... |
Does Knockout of Isl2 in Regulatory T cell causally result in protein/peptide accumulation? | 0 | 1,481 | Knockout | Isl2 | protein/peptide accumulation | Regulatory T cell | Gene: Isl2 (insulin related protein 2 (islet 2))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: axonogenesis, negative regulation of neuron differentiation, neuron development, neuron fate commitment, neuron fate specification, positive regulation of transcription by RNA... |
Does Knockout of Sema6c in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,680 | Knockout | Sema6c | protein/peptide distribution | myoblast cell line | Gene: Sema6c (sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: axon guidance, cell differentiation, negative chemotaxis, negative regulation of axon extension, nervous system development, neur... |
Does Knockout of Inpp5k in Regulatory T cell causally result in cell proliferation? | 0 | 1,484 | Knockout | Inpp5k | cell proliferation | Regulatory T cell | Gene: Inpp5k (inositol polyphosphate 5-phosphatase K)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, cellular response to cAMP, cellular response to epidermal growth factor stimulus, cellular response to hormone stimulus, cel... |
Does Knockout of AB124611 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 2,307 | Knockout | AB124611 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: AB124611 (cDNA sequence AB124611)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: cellular_component, membrane
Pathways:
UniProt: A0A0B4J1G2, Z4YNA9
Entrez ID: 382062 |
Does Knockout of Rsad2 in Melanoma Cell Line causally result in protein/peptide accumulation? | 0 | 1,839 | Knockout | Rsad2 | protein/peptide accumulation | Melanoma Cell Line | Gene: Rsad2 (radical S-adenosyl methionine domain containing 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: CD4-positive, alpha-beta T cell activation, CD4-positive, alpha-beta T cell differentiation, defense response to virus, immune system process, innate immune res... |
Does Knockout of Trib1 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 688 | Knockout | Trib1 | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Trib1 (tribbles pseudokinase 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of JNK cascade, negative regulation of MAPK cascade, negative regulation of lipopolysaccharide-mediated signaling pathway, negative regulation of neutrophil different... |
Does Knockout of Plekho1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,565 | Knockout | Plekho1 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: Plekho1 (pleckstrin homology domain containing, family O member 1)
Type: protein-coding
Summary: Acts upstream of or within several processes, including lamellipodium morphogenesis; myoblast fusion; and myoblast migration. Located in muscle cell projection membrane and ruffle membrane. Orthologous... |
Does Knockout of Zfp428 in Neuroblastoma Cell Line causally result in response to virus? | 0 | 1,422 | Knockout | Zfp428 | response to virus | Neuroblastoma Cell Line | Gene: Zfp428 (zinc finger protein 428)
Type: protein-coding
Summary: Predicted to enable zinc ion binding activity. Is expressed in cortical plate. Orthologous to human ZNF428 (zinc finger protein 428). [provided by Alliance of Genome Resources, Jul 2025]
Gene Ontology: MF: metal ion binding, m... |
Does Knockout of Npm3 in macrophage causally result in phagocytosis? | 0 | 1,889 | Knockout | Npm3 | phagocytosis | macrophage | Gene: Npm3 (nucleoplasmin 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin remodeling, rRNA processing, rRNA transcription; MF: RNA binding, chromatin binding, histone binding, protein binding; CC: actin cytoskeleton, cytoplasm, cytosol, nucleolus, nucleoplasm... |
Does Knockout of Dmrt3 in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,685 | Knockout | Dmrt3 | protein/peptide distribution | myoblast cell line | Gene: Dmrt3 (doublesex and mab-3 related transcription factor 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: adult locomotory behavior, adult walking behavior, cell differentiation, male sex differentiation, regulation of DNA-templated transcription, regulation of odo... |
Does Knockout of Fzd10 in Melanoma Cell Line causally result in cell proliferation? | 0 | 1,270 | Knockout | Fzd10 | cell proliferation | Melanoma Cell Line | Gene: Fzd10 (frizzled class receptor 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, Wnt signaling pathway, canonical Wnt signaling pathway, cell surface receptor signaling pathway, non-canonical Wnt signaling pathway, pos... |
Does Knockout of Jak2 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,260 | Knockout | Jak2 | cell proliferation | Mouse kidney carcinoma cell | Gene: Jak2 (Janus kinase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: T-helper 1 cell differentiation, activation of Janus kinase activity, adaptive immune response, apoptotic signaling pathway, axon regeneration, cell adhesion, cell differentiation, cell surface re... |
Does Knockout of Ssbp1 in breast epithelium causally result in cell cycle progression? | 0 | 1,470 | Knockout | Ssbp1 | cell cycle progression | breast epithelium | Gene: Ssbp1 (single-stranded DNA binding protein 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: DNA replication, DNA-templated DNA replication, mitochondrion organization, positive regulation of mitochondrial DNA replication, protein homotetramerization; MF: DNA bindi... |
Does Knockout of Gm9758 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 1 | 83 | Knockout | Gm9758 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Gm9758 (predicted gene 9758)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q80ZT2
Entrez ID: 381714 |
Does Knockout of Anks1 in renal medulla cell line causally result in response to bacteria? | 0 | 2,049 | Knockout | Anks1 | response to bacteria | renal medulla cell line | Gene: Anks1 (ankyrin repeat and SAM domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ephrin receptor signaling pathway, negative regulation of ubiquitin-dependent protein catabolic process, neuron remodeling, regulation of ephrin receptor signaling pat... |
Does Knockout of Vmn2r10 in pro-B-lymphocyte causally result in response to chemicals? | 0 | 1,720 | Knockout | Vmn2r10 | response to chemicals | pro-B-lymphocyte | Gene: Vmn2r10 (vomeronasal 2, receptor 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane
Pathways:
UniProt: O3520... |
Does Knockout of Plb1 in Colonic Cancer Cell Line causally result in tumorigenicity? | 0 | 2,177 | Knockout | Plb1 | tumorigenicity | Colonic Cancer Cell Line | Gene: Plb1 (phospholipase B1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: diacylglycerol catabolic process, lipid metabolic process, phosphatidylcholine catabolic process, phosphatidylethanolamine catabolic process, phosphatidylglycerol catabolic process, phospholipid... |
Does Knockout of Mir3072 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity? | 0 | 688 | Knockout | Mir3072 | tumorigenicity | Immortal Mouse Liver-derived Cell Line | Gene: Mir3072 (microRNA 3072)
Type: ncRNA
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase... |
Does Knockout of Atp6v0d2 in Colonic Cancer Cell Line causally result in tumorigenicity? | 0 | 2,181 | Knockout | Atp6v0d2 | tumorigenicity | Colonic Cancer Cell Line | Gene: Atp6v0d2 (ATPase, H+ transporting, lysosomal V0 subunit D2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: monoatomic ion transport, proton transmembrane transport, vacuolar acidification, vacuolar transport; CC: apical plasma membrane, early endosome, endosome, me... |
Does Knockout of Fbxo24 in Embryonic Cell Line causally result in protein/peptide accumulation? | 0 | 1,440 | Knockout | Fbxo24 | protein/peptide accumulation | Embryonic Cell Line | Gene: Fbxo24 (F-box protein 24)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: axoneme assembly, biological_process, chromatin organization, cilium organization, mRNA splicing, via spliceosome, mitochondrion organization, piRNA processing, protein catabolic process, sing... |
Does Knockout of Asmt in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,266 | Knockout | Asmt | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Asmt (acetylserotonin O-methyltransferase)
Type: protein-coding
Summary: This gene belongs to the methyltransferase superfamily and is located in the pseudoautosomal region (PAR) of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin and is abunda... |
Does Knockout of Supt7l in Mouse kidney carcinoma cell causally result in cell proliferation? | 1 | 1,286 | Knockout | Supt7l | cell proliferation | Mouse kidney carcinoma cell | Gene: Supt7l (SPT7-like, STAGA complex gamma subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: maintenance of protein location in nucleus, positive regulation of DNA-templated transcription, regulation of DNA repair, regulation of RNA splicing; MF: protein heterodi... |
Does Knockout of Pcdh15 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,284 | Knockout | Pcdh15 | cell proliferation | Mouse kidney carcinoma cell | Gene: Pcdh15 (protocadherin 15)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: actin filament bundle assembly, actin filament organization, adult walking behavior, auditory receptor cell stereocilium organization, cell adhesion, detection of mechanical stimulus involved ... |
Does Knockout of Hspg2 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,681 | Knockout | Hspg2 | protein/peptide distribution | myoblast cell line | Gene: Hspg2 (perlecan (heparan sulfate proteoglycan 2))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: angiogenesis, animal organ morphogenesis, brain development, cardiac muscle tissue development, cartilage development involved in endochondral bone morphogenesis, cell ... |
Does Knockout of Phospho2 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,278 | Knockout | Phospho2 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Phospho2 (phosphatase, orphan 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: hydrolase activity, metal ion binding, phosphatase activity, pyridoxal phosphatase activity
Pathways: Vitamin B6 metabolism - Mus musculus (mouse)
UniProt: Q9D9M5
... |
Does Knockout of Ugt2a2 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity? | 0 | 2,175 | Knockout | Ugt2a2 | tumorigenicity | Breast Adenocarcinoma Cell Line | Gene: Ugt2a2 (UDP glucuronosyltransferase 2 family, polypeptide A2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: bile acid metabolic process, lipid metabolic process, response to symbiont, xenobiotic metabolic process; MF: UDP-glycosyltransferase activity, glucuronosyl... |
Does Knockout of Slc6a12 in Melanoma Cell Line causally result in cell proliferation? | 0 | 2,488 | Knockout | Slc6a12 | cell proliferation | Melanoma Cell Line | Gene: Slc6a12 (solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: amino acid transport, gamma-aminobutyric acid transport, glycine betaine transport, intracellular water homeostasis, monocarboxy... |
Does Knockout of Dffa in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,264 | Knockout | Dffa | cell proliferation | Colonic Cancer Cell Line | Gene: Dffa (DNA fragmentation factor, alpha subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic DNA fragmentation, apoptotic process, negative regulation of apoptotic DNA fragmentation, negative regulation of execution phase of apoptosis, positive regulatio... |
Does Knockout of Mfap2 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,284 | Knockout | Mfap2 | cell proliferation | Mouse kidney carcinoma cell | Gene: Mfap2 (microfibrillar-associated protein 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: embryonic eye morphogenesis, platelet formation, positive regulation of cold-induced thermogenesis, post-embryonic eye morphogenesis; MF: extracellular matrix structural cons... |
Does Knockout of Pcdhgb2 in Mammary Gland Tumor Cell Line causally result in cell proliferation? | 0 | 1,274 | Knockout | Pcdhgb2 | cell proliferation | Mammary Gland Tumor Cell Line | Gene: Pcdhgb2 (protocadherin gamma subfamily B, 2)
Type: protein-coding
Summary: Predicted to be involved in cell adhesion. Located in membrane. Is expressed in brain and cerebral cortex. Orthologous to human PCDHGB2 (protocadherin gamma subfamily B, 2). [provided by Alliance of Genome Resources, Apr 20... |
Does Knockout of Npy1r in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,285 | Knockout | Npy1r | cell proliferation | Mouse kidney carcinoma cell | Gene: Npy1r (neuropeptide Y receptor Y1)
Type: protein-coding
Summary: Enables pancreatic polypeptide receptor activity and peptide YY receptor activity. Acts upstream of or within several processes, including feeding behavior; glucose metabolic process; and sensory perception of pain. Predicted to be l... |
Does Knockout of Pde6g in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,262 | Knockout | Pde6g | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Pde6g (phosphodiesterase 6G, cGMP-specific, rod, gamma)
Type: protein-coding
Summary: Predicted to enable spectrin binding activity. Acts upstream of or within positive regulation of G protein-coupled receptor signaling pathway; positive regulation of MAPK cascade; and positive regulation of epide... |
Does Knockout of Mpc2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 81 | Knockout | Mpc2 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Mpc2 (mitochondrial pyruvate carrier 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: positive regulation of insulin secretion involved in cellular response to glucose stimulus, pyruvate decarboxylation to acetyl-CoA, pyruvate import into mitochondria; MF: identic... |
Does Knockout of Slc5a10 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,289 | Knockout | Slc5a10 | cell proliferation | Mouse kidney carcinoma cell | Gene: Slc5a10 (solute carrier family 5 (sodium/glucose cotransporter), member 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: carbohydrate transmembrane transport, fructose transmembrane transport, hexose transmembrane transport, mannose transmembrane transport, monoa... |
Does Knockout of Zc3hc1 in Melanoma Cell Line causally result in cell proliferation? | 0 | 1,281 | Knockout | Zc3hc1 | cell proliferation | Melanoma Cell Line | Gene: Zc3hc1 (zinc finger, C3HC type 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell division, protein ubiquitination; MF: metal ion binding, protein kinase binding, zinc ion binding; CC: nuclear envelope, nuclear membrane, nuclear pore nuclear basket, nucleoplasm... |
Does Knockout of Efna2 in Colonic Cancer Cell Line causally result in tumorigenicity? | 0 | 2,181 | Knockout | Efna2 | tumorigenicity | Colonic Cancer Cell Line | Gene: Efna2 (ephrin A2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: axon guidance, bone remodeling, ephrin receptor signaling pathway, olfactory bulb development, osteoclast differentiation; MF: ephrin receptor binding, protein binding; CC: membrane, neuromuscular jun... |
Does Knockout of Hoxd8 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals? | 0 | 1,565 | Knockout | Hoxd8 | response to chemicals | Pancreatic Ductal Adenocarcinoma Cell Line | Gene: Hoxd8 (homeobox D8)
Type: protein-coding
Summary: Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within anterior/posterior pattern specifi... |
Does Knockout of Mir7224 in breast epithelium causally result in cell cycle progression? | 0 | 1,468 | Knockout | Mir7224 | cell cycle progression | breast epithelium | Gene: Mir7224 (microRNA 7224)
Type: ncRNA
Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase... |
Does Knockout of Riox2 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 1,130 | Knockout | Riox2 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Riox2 (ribosomal oxygenase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: chromatin remodeling, negative regulation of DNA-templated transcription, regulation of cell population proliferation, ribosome biogenesis; MF: dioxygenase activity, histone H3K36 demethyl... |
Does Knockout of Tas2r139 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype? | 0 | 1,130 | Knockout | Tas2r139 | regulation of signal transduction phenotype | Embryonic Fibroblast Cell Line | Gene: Tas2r139 (taste receptor, type 2, member 139)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, detection of chemical stimulus involved in sensory perception of bitter taste, detection of chemical stimulus involved in sens... |
Does Knockout of Acacb in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,285 | Knockout | Acacb | cell proliferation | Mouse kidney carcinoma cell | Gene: Acacb (acetyl-Coenzyme A carboxylase beta)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: D-glucose import, acetyl-CoA metabolic process, acyl-CoA metabolic process, energy homeostasis, fatty acid biosynthetic process, fatty acid metabolic process, fatty acid oxida... |
Does Knockout of Zfp873 in Microglial Cell Line causally result in response to virus? | 0 | 2,429 | Knockout | Zfp873 | response to virus | Microglial Cell Line | Gene: Zfp873 (zinc finger protein 873)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: developmental process, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polym... |
Does Knockout of Galnt10 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,679 | Knockout | Galnt10 | protein/peptide distribution | myoblast cell line | Gene: Galnt10 (polypeptide N-acetylgalactosaminyltransferase 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: protein O-linked glycosylation, protein O-linked glycosylation via N-acetyl-galactosamine, protein glycosylation; MF: carbohydrate binding, glycosyltransferase... |
Does Knockout of Csn2 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,683 | Knockout | Csn2 | protein/peptide distribution | myoblast cell line | Gene: Csn2 (casein beta)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: extracellular region, extracellular space
Pathways: Prolactin signaling pathway - Mus musculus (mouse)
UniProt: P10598
Entrez ID: 12991 |
Does Knockout of Gm5447 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,262 | Knockout | Gm5447 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Gm5447 (predicted gene 5447)
Type:
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt:
Entrez ID: |
Does Knockout of Fggy in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,286 | Knockout | Fggy | cell proliferation | Mouse kidney carcinoma cell | Gene: Fggy (FGGY carbohydrate kinase domain containing)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: carbohydrate metabolic process, carbohydrate phosphorylation, neuron cellular homeostasis, pentose metabolic process; MF: D-ribulokinase activity, kinase activity, phos... |
Does Knockout of Sel1l3 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,271 | Knockout | Sel1l3 | cell proliferation | Mouse kidney carcinoma cell | Gene: Sel1l3 (sel-1 suppressor of lin-12-like 3 (C. elegans))
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q80TS8
Entrez ID: 231238 |
Does Knockout of P3h3 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,680 | Knockout | P3h3 | protein/peptide distribution | myoblast cell line | Gene: P3h3 (prolyl 3-hydroxylase 3)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: collagen biosynthetic process, collagen metabolic process, negative regulation of cell population proliferation, peptidyl-lysine hydroxylation; MF: L-ascorbic acid binding, dioxygenase act... |
Does Knockout of Zfp457 in macrophage causally result in phagocytosis? | 0 | 1,890 | Knockout | Zfp457 | phagocytosis | macrophage | Gene: Zfp457 (zinc finger protein 457)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: negative regulation of transcription by RNA polymerase II, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, metal ion bindin... |
Does Knockout of Spns2 in Melanoma Cell Line causally result in cell proliferation? | 0 | 2,492 | Knockout | Spns2 | cell proliferation | Melanoma Cell Line | Gene: Spns2 (SPNS lysolipid transporter 2, sphingosine-1-phosphate)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell homeostasis, T cell homeostasis, bone development, lipid transport, lymph node development, lymphocyte homeostasis, lymphocyte migration, regulation ... |
Does Knockout of Defb33 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 578 | Knockout | Defb33 | cell proliferation | Embryonic Stem Cell Line | Gene: Defb33 (defensin beta 33)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell chemotaxis, defense response, defense response to bacterium, positive chemotaxis; MF: CCR6 chemokine receptor binding, chemoattractant activity; CC: extracellular region, extracellular sp... |
Does Knockout of Golim4 in Melanoma Cell Line causally result in cell proliferation? | 0 | 1,838 | Knockout | Golim4 | cell proliferation | Melanoma Cell Line | Gene: Golim4 (golgi integral membrane protein 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: CC: Golgi apparatus, Golgi cisterna membrane, Golgi membrane, endosome, endosome membrane, membrane
Pathways:
UniProt: Q8BXA1
Entrez ID: 73124 |
Does Knockout of Osbpl5 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 83 | Knockout | Osbpl5 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Osbpl5 (oxysterol binding protein-like 5)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: intermembrane lipid transfer, lipid transport, phospholipid transport; MF: cholesterol binding, lipid binding, phosphatidylinositol-4-phosphate binding, phosphatidylserine bind... |
Does Knockout of Kcnj16 in myoblast cell line causally result in protein/peptide distribution? | 0 | 1,684 | Knockout | Kcnj16 | protein/peptide distribution | myoblast cell line | Gene: Kcnj16 (potassium inwardly-rectifying channel, subfamily J, member 16)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: monoatomic ion transmembrane transport, monoatomic ion transport, potassium ion import across plasma membrane, potassium ion transmembrane transpor... |
Does Knockout of Snx7 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 1,263 | Knockout | Snx7 | cell proliferation | Colonic Cancer Cell Line | Gene: Snx7 (sorting nexin 7)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: endocytic recycling, mitophagy, piecemeal microautophagy of the nucleus, positive regulation of autophagosome assembly, protein transport, reticulophagy; MF: lipid binding, phosphatidylinositol b... |
Does Knockout of Tie1 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,259 | Knockout | Tie1 | cell proliferation | Mouse kidney carcinoma cell | Gene: Tie1 (tyrosine kinase with immunoglobulin-like and EGF-like domains 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: angiogenesis, aortic valve morphogenesis, blood vessel development, branching involved in lymph vessel morphogenesis, branching morphogenesis of an... |
Does Knockout of AW209491 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,286 | Knockout | AW209491 | cell proliferation | Mouse kidney carcinoma cell | Gene: AW209491 (expressed sequence AW209491)
Type: protein-coding
Summary: No summary available.
Gene Ontology:
Pathways:
UniProt: Q91WD4
Entrez ID: 105351 |
Does Knockout of Mttp in macrophage causally result in response to bacteria? | 0 | 2,211 | Knockout | Mttp | response to bacteria | macrophage | Gene: Mttp (microsomal triglyceride transfer protein)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: ceramide 1-phosphate transport, cholesterol homeostasis, cholesterol metabolic process, circadian rhythm, establishment of localization in cell, gene expression, glutamin... |
Does Knockout of Gna12 in Colonic Cancer Cell Line causally result in cell proliferation? | 0 | 2,179 | Knockout | Gna12 | cell proliferation | Colonic Cancer Cell Line | Gene: Gna12 (guanine nucleotide binding protein, alpha 12)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, Rho protein signal transduction, Rho-activating G protein-coupled receptor signaling pathway, adenylate cyclase-modulat... |
Does Knockout of Ttbk2 in Immortal mouse chromaffin cells causally result in cell viability? | 0 | 2,469 | Knockout | Ttbk2 | cell viability | Immortal mouse chromaffin cells | Gene: Ttbk2 (tau tubulin kinase 2)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell projection organization, cerebellar granular layer development, cerebellar granule cell precursor tangential migration, cerebellum development, cilium assembly, embryonic brain develop... |
Does Knockout of a in Melanoma Cell Line causally result in cell proliferation? | 0 | 1,269 | Knockout | a | cell proliferation | Melanoma Cell Line | Gene: a (nonagouti)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: adult feeding behavior, epigenetic programming in the zygotic pronuclei, epigenetic regulation of gene expression, generation of precursor metabolites and energy, hormone-mediated signaling pathway, melan... |
Does Knockout of Ptprz1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation? | 0 | 1,277 | Knockout | Ptprz1 | cell proliferation | Breast Adenocarcinoma Cell Line | Gene: Ptprz1 (protein tyrosine phosphatase receptor type Z, polypeptide 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: axonal fasciculation, axonogenesis, hematopoietic progenitor cell differentiation, learning or memory, negative regulation of cell population prolife... |
Does Knockout of Tmem9 in macrophage causally result in phagocytosis? | 0 | 1,889 | Knockout | Tmem9 | phagocytosis | macrophage | Gene: Tmem9 (transmembrane protein 9)
Type: protein-coding
Summary: Involved in positive regulation of canonical Wnt signaling pathway and regulation of protein catabolic process. Predicted to be located in bounding membrane of organelle; intercellular bridge; and mitotic spindle. Is expressed in centra... |
Does Knockout of Nlrp10 in Melanoma Cell Line causally result in protein/peptide accumulation? | 1 | 1,839 | Knockout | Nlrp10 | protein/peptide accumulation | Melanoma Cell Line | Gene: Nlrp10 (NLR family, pyrin domain containing 10)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: activation of innate immune response, adaptive immune response, defense response, defense response to fungus, immune system process, inflammatory response, innate immune ... |
Does Knockout of Tdrd6 in Mouse cell causally result in protein/peptide accumulation? | 0 | 1,047 | Knockout | Tdrd6 | protein/peptide accumulation | Mouse cell | Gene: Tdrd6 (tudor domain containing 6)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: P granule organization, cell differentiation, germ cell development, oogenesis, piRNA processing, spermatogenesis, spliceosomal snRNP assembly; CC: P granule, chromatoid body, cytoplas... |
Does Knockout of Kif1c in myoblast cell line causally result in protein/peptide distribution? | 1 | 1,683 | Knockout | Kif1c | protein/peptide distribution | myoblast cell line | Gene: Kif1c (kinesin family member 1C)
Type: protein-coding
Summary: Predicted to enable ATP hydrolysis activity; microtubule binding activity; and plus-end-directed microtubule motor activity. Acts upstream of or within retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Located in G... |
Does Knockout of Elp2 in Embryonic Fibroblast Cell Line causally result in cell proliferation? | 1 | 345 | Knockout | Elp2 | cell proliferation | Embryonic Fibroblast Cell Line | Gene: Elp2 (elongator acetyltransferase complex subunit 2)
Type: protein-coding
Summary: Enables protein kinase binding activity. Acts upstream of or within regulation of receptor signaling pathway via JAK-STAT. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of elongator holoen... |
Does Knockout of Adk in Pancreatic Cancer Cell Line causally result in response to chemicals? | 0 | 2,359 | Knockout | Adk | response to chemicals | Pancreatic Cancer Cell Line | Gene: Adk (adenosine kinase)
Type: protein-coding
Summary: Enables adenosine kinase activity and deoxyadenosine kinase activity. Involved in AMP salvage; GMP salvage; and dAMP salvage. Acts upstream of or within dATP biosynthetic process and purine ribonucleoside salvage. Located in nucleus. Is active i... |
Does Knockout of Rcsd1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 82 | Knockout | Rcsd1 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Rcsd1 (RCSD domain containing 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular hyperosmotic response, protein localization to endosome, retrograde transport, endosome to Golgi, skeletal muscle contraction; MF: actin filament binding, phosphatidylinositol ... |
Does Knockout of Vmn1r200 in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 579 | Knockout | Vmn1r200 | cell proliferation | Embryonic Stem Cell Line | Gene: Vmn1r200 (vomeronasal 1 receptor 200)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromon... |
Does Knockout of Tarbp2 in macrophage causally result in phagocytosis? | 0 | 1,888 | Knockout | Tarbp2 | phagocytosis | macrophage | Gene: Tarbp2 (TARBP2, RISC loading complex RNA binding subunit)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: RISC complex assembly, cytoplasmic pattern recognition receptor signaling pathway, global gene silencing by mRNA cleavage, miRNA processing, multicellular organ... |
Does Knockout of Serhl in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,287 | Knockout | Serhl | cell proliferation | Mouse kidney carcinoma cell | Gene: Serhl (serine hydrolase-like)
Type: protein-coding
Summary: No summary available.
Gene Ontology: MF: hydrolase activity; CC: cytoplasm, cytoplasmic vesicle, mitochondrion, perinuclear region of cytoplasm, peroxisome
Pathways:
UniProt: Q9EPB5
Entrez ID: 68607 |
Does Knockout of Icosl in Melanoma Cell Line causally result in cell proliferation? | 0 | 2,488 | Knockout | Icosl | cell proliferation | Melanoma Cell Line | Gene: Icosl (icos ligand)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell activation, T cell activation, T cell receptor signaling pathway, T follicular helper cell differentiation, adaptive immune response, immune system process, isotype switching, positive regula... |
Does Knockout of Gapt in Melanoma Cell Line causally result in protein/peptide accumulation? | 0 | 1,839 | Knockout | Gapt | protein/peptide accumulation | Melanoma Cell Line | Gene: Gapt (Grb2-binding adaptor, transmembrane)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: B cell activation, B cell homeostasis, B cell proliferation involved in immune response; CC: Golgi apparatus, membrane, plasma membrane
Pathways:
UniProt: Q... |
Does Knockout of Cks1b in Embryonic Stem Cell Line causally result in cell proliferation? | 0 | 578 | Knockout | Cks1b | cell proliferation | Embryonic Stem Cell Line | Gene: Cks1b (CDC28 protein kinase 1b)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell division, fibroblast proliferation, mitotic cell cycle phase transition, regulation of DNA-templated transcription, regulation of mitotic cell cycle; MF: cyclin-dependent protein se... |
Does Knockout of Thada in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,284 | Knockout | Thada | cell proliferation | Mouse kidney carcinoma cell | Gene: Thada (thyroid adenoma associated)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: lipid homeostasis, negative regulation of endoplasmic reticulum calcium ion concentration, tRNA methylation, tRNA nucleoside ribose methylation, tRNA processing; MF: enzyme regulator ... |
Does Knockout of Sacm1l in Colonic Cancer Cell Line causally result in cell proliferation? | 1 | 1,276 | Knockout | Sacm1l | cell proliferation | Colonic Cancer Cell Line | Gene: Sacm1l (SAC1 suppressor of actin mutations 1-like (yeast))
Type: protein-coding
Summary: This gene encodes an integral membrane protein, which is localized to the endoplasmic reticulum, and functions as a phosphoinositide phosphatase that hydrolyzes phosphatidylinositol 3-phosphate, phosphatidylin... |
Does Knockout of Rfx4 in cardiac muscle cell line causally result in protein/peptide accumulation? | 0 | 1,662 | Knockout | Rfx4 | protein/peptide accumulation | cardiac muscle cell line | Gene: Rfx4 (regulatory factor X, 4 (influences HLA class II expression))
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cerebellar cortex morphogenesis, cilium assembly, dorsal spinal cord development, forebrain development, midbrain development, negative regulation of s... |
Does Knockout of Unc13a in breast epithelium causally result in cell cycle progression? | 0 | 1,470 | Knockout | Unc13a | cell cycle progression | breast epithelium | Gene: Unc13a (unc-13 homolog A)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: SNARE complex assembly, amyloid-beta metabolic process, cell differentiation, chemical synaptic transmission, dense core granule docking, dense core granule priming, exocytosis, innervation, l... |
Does Knockout of Tm9sf4 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation? | 0 | 82 | Knockout | Tm9sf4 | cell proliferation | Pre-B-Lymphocyte Cell Line | Gene: Tm9sf4 (transmembrane 9 superfamily member 4)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cell adhesion, phagocytosis, positive regulation of protein exit from endoplasmic reticulum, positive regulation of protein localization to cell surface, protein localizati... |
Does Knockout of Piezo1 in Pancreatic Cancer Cell Line causally result in response to chemicals? | 0 | 2,359 | Knockout | Piezo1 | response to chemicals | Pancreatic Cancer Cell Line | Gene: Piezo1 (piezo-type mechanosensitive ion channel component 1)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: cellular response to mechanical stimulus, detection of mechanical stimulus, monoatomic cation transmembrane transport, monoatomic cation transport, monoatomi... |
Does Knockout of Kcnip3 in Melanoma Cell Line causally result in cell proliferation? | 0 | 1,282 | Knockout | Kcnip3 | cell proliferation | Melanoma Cell Line | Gene: Kcnip3 (Kv channel interacting protein 3, calsenilin)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: apoptotic process, behavioral response to pain, intracellular protein transport, monoatomic ion transmembrane transport, monoatomic ion transport, negative regulati... |
Does Knockout of Zfp449 in Mouse kidney carcinoma cell causally result in cell proliferation? | 0 | 1,289 | Knockout | Zfp449 | cell proliferation | Mouse kidney carcinoma cell | Gene: Zfp449 (zinc finger protein 449)
Type: protein-coding
Summary: No summary available.
Gene Ontology: BP: regulation of transcription by RNA polymerase II, spermatogonial cell division; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II... |
Does Knockout of Angpt4 in Microglial Cell Line causally result in response to virus? | 0 | 1,439 | Knockout | Angpt4 | response to virus | Microglial Cell Line | Gene: Angpt4 (angiopoietin 4)
Type: protein-coding
Summary: This gene is a member of the angiopoietin family of secreted growth factors comprising Angiopoietins-1, -2, and -3, all of which bind the TEK Receptor Tyrosine Kinase. Angiopoietin/TEK Receptor Tyrosine Kinase signaling is involved in survival ... |
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