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Does Knockout of Arsj in myoblast cell line causally result in protein/peptide distribution?
0
1,680
Knockout
Arsj
protein/peptide distribution
myoblast cell line
Gene: Arsj (arylsulfatase J) Type: protein-coding Summary: No summary available. Gene Ontology: MF: hydrolase activity, metal ion binding, sulfuric ester hydrolase activity; CC: actin cytoskeleton, extracellular region Pathways: Gamma carboxylation, hypusinylation, hydroxylation, and a...
Does Knockout of Zscan26 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,268
Knockout
Zscan26
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Zscan26 (zinc finger and SCAN domain containing 26) Type: protein-coding Summary: No summary available. Gene Ontology: MF: DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-spe...
Does Knockout of Banf1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Banf1
cell proliferation
Mouse kidney carcinoma cell
Gene: Banf1 (BAF nuclear assembly factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA integration, DNA repair, cGAS/STING signaling pathway, chromatin organization, chromosome organization, establishment of integrated proviral latency, mitotic nuclear membrane r...
Does Knockout of Trim62 in myoblast cell line causally result in protein/peptide distribution?
0
1,681
Knockout
Trim62
protein/peptide distribution
myoblast cell line
Gene: Trim62 (tripartite motif-containing 62) Type: protein-coding Summary: No summary available. Gene Ontology: BP: immune system process, innate immune response, negative regulation of epithelial to mesenchymal transition, negative regulation of viral transcription, positive regulation of DNA...
Does Knockout of Pfkfb2 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Pfkfb2
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Pfkfb2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: carbohydrate phosphorylation, fructose 2,6-bisphosphate metabolic process, fructose metabolic process, gluconeogenesis, glucose catabolic process, glycolyt...
Does Knockout of Ablim3 in cardiac muscle cell line causally result in protein/peptide accumulation?
0
1,662
Knockout
Ablim3
protein/peptide accumulation
cardiac muscle cell line
Gene: Ablim3 (actin binding LIM protein family, member 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cilium assembly, cytoskeleton organization, lamellipodium assembly, positive regulation of transcription by RNA polymerase II, transcription by RNA polymerase II; MF:...
Does Knockout of Rbm34 in macrophage causally result in phagocytosis?
0
1,888
Knockout
Rbm34
phagocytosis
macrophage
Gene: Rbm34 (RNA binding motif protein 34) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); MF: RNA binding, molecular_function, nucleic acid binding; CC: chromoso...
Does Knockout of Tbc1d10c in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Tbc1d10c
cell proliferation
Embryonic Stem Cell Line
Gene: Tbc1d10c (TBC1 domain family, member 10c) Type: protein-coding Summary: No summary available. Gene Ontology: BP: negative regulation of B cell activation, negative regulation of ERK1 and ERK2 cascade, negative regulation of calcineurin-NFAT signaling cascade, retrograde transport, endosom...
Does Knockout of Wnt4 in Melanoma Cell Line causally result in protein/peptide accumulation?
0
1,839
Knockout
Wnt4
protein/peptide accumulation
Melanoma Cell Line
Gene: Wnt4 (wingless-type MMTV integration site family, member 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Sertoli cell differentiation, T cell differentiation in thymus, Wnt signaling pathway, adrenal gland development, animal organ morphogenesis, branching involv...
Does Knockout of Coq8b in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Coq8b
cell cycle progression
breast epithelium
Gene: Coq8b (coenzyme Q8B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cerebellar Purkinje cell layer morphogenesis, protein phosphorylation, ubiquinone biosynthetic process; MF: ATP binding, kinase activity, nucleotide binding, protein kinase activity, transferase ac...
Does Knockout of Fuom in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Fuom
cell proliferation
Mouse kidney carcinoma cell
Gene: Fuom (fucose mutarotase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: GDP-L-fucose salvage, female mating behavior, fucose metabolic process, fucosylation, monosaccharide metabolic process, negative regulation of neuron differentiation; MF: L-fucose mutarotase ac...
Does Knockout of Slamf6 in Melanoma Cell Line causally result in cell proliferation?
0
1,838
Knockout
Slamf6
cell proliferation
Melanoma Cell Line
Gene: Slamf6 (SLAM family member 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: T cell activation, T-helper 17 cell lineage commitment, adaptive immune response, immune response, immune system process, innate immune response, natural killer cell differentiation, natur...
Does Knockout of Sim1 in Embryonic Fibroblast Cell Line causally result in response to virus?
1
1,133
Knockout
Sim1
response to virus
Embryonic Fibroblast Cell Line
Gene: Sim1 (single-minded family bHLH transcription factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, nervous system development, regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II, system development,...
Does Knockout of Cep72 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,268
Knockout
Cep72
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Cep72 (centrosomal protein 72) Type: protein-coding Summary: No summary available. Gene Ontology: BP: centriole replication, gamma-tubulin complex localization, regulation of protein localization to centrosome, spindle organization; CC: centriolar satellite, centrosome, ciliary basal body...
Does Knockout of Cd200r3 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Cd200r3
cell proliferation
Mouse kidney carcinoma cell
Gene: Cd200r3 (CD200 receptor 3) Type: protein-coding Summary: No summary available. Gene Ontology: MF: protein binding, signaling receptor activity; CC: cell surface, external side of plasma membrane, membrane, plasma membrane Pathways: Kaposi sarcoma-associated herpesvirus infection ...
Does Knockout of Zfp786 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Zfp786
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Zfp786 (zinc finger protein 786) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, metal ion binding, zinc ion binding; CC: nucleus Pathways: Gene ex...
Does Knockout of Unc45b in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Unc45b
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Unc45b (unc-45 myosin chaperone B) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, lens development in camera-type eye, muscle organ development, protein folding; MF: Hsp90 protein binding; CC: A band, Z disc, cytoplasm, cytosol, perinuclear re...
Does Knockout of Plec in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Plec
cell cycle progression
breast epithelium
Gene: Plec (plectin) Type: protein-coding Summary: Plectin is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton. Plakins, with their multi-domain stru...
Does Knockout of Vdac3-ps1 in Embryonic Fibroblast Cell Line causally result in cell proliferation?
0
345
Knockout
Vdac3-ps1
cell proliferation
Embryonic Fibroblast Cell Line
Gene: Vdac3-ps1 (voltage-dependent anion channel 3, pseudogene 1) Type: Summary: No summary available. Gene Ontology: Pathways: UniProt: Entrez ID:
Does Knockout of Nub1 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
Nub1
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Nub1 (negative regulator of ubiquitin-like proteins 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of proteasomal ubiquitin-dependent protein catabolic process, proteasomal protein catabolic process, protein ubiquitination, proteolysis involv...
Does Knockout of Mir680-2 in breast epithelium causally result in cell cycle progression?
0
1,470
Knockout
Mir680-2
cell cycle progression
breast epithelium
Gene: Mir680-2 (microRNA 680-2) Type: ncRNA Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymera...
Does Knockout of Krt8 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Krt8
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Krt8 (keratin 8) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation involved in embryonic placenta development, extrinsic apoptotic signaling pathway, hepatocyte apoptotic process, response to hydrostatic pressure, response to other organism, sarco...
Does Knockout of Actr2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
1
84
Knockout
Actr2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Actr2 (actin related protein 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Arp2/3 complex-mediated actin nucleation, actin cytoskeleton organization, asymmetric cell division, cellular response to type II interferon, cilium assembly, cytosolic transport, establ...
Does Knockout of Pcyt1a in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Pcyt1a
cell proliferation
Mouse kidney carcinoma cell
Gene: Pcyt1a (phosphate cytidylyltransferase 1, choline, alpha isoform) Type: protein-coding Summary: Enables choline-phosphate cytidylyltransferase activity. Involved in B cell proliferation; CDP-choline pathway; and isotype switching. Located in endoplasmic reticulum membrane and glycogen granule. Is ...
Does Knockout of Zfp981 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,286
Knockout
Zfp981
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfp981 (zinc finger protein 981) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II...
Does Knockout of Acd in Colonic Cancer Cell Line causally result in cell proliferation?
1
1,264
Knockout
Acd
cell proliferation
Colonic Cancer Cell Line
Gene: Acd (adrenocortical dysplasia) Type: protein-coding Summary: No summary available. Gene Ontology: BP: embryonic limb morphogenesis, establishment of protein localization to telomere, intracellular protein transport, negative regulation of telomere maintenance via telomerase, positive regu...
Does Knockout of Pfas in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,176
Knockout
Pfas
cell proliferation
Colonic Cancer Cell Line
Gene: Pfas (phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 'de novo' AMP biosynthetic process, 'de novo' IMP biosynthetic process, 'de novo' XMP biosynthetic process, GMP biosynthetic process, anterior h...
Does Knockout of Rpe65 in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Rpe65
cell proliferation
Embryonic Stem Cell Line
Gene: Rpe65 (retinal pigment epithelium 65) Type: protein-coding Summary: No summary available. Gene Ontology: BP: camera-type eye development, circadian rhythm, detection of light stimulus involved in visual perception, lipid metabolic process, neural retina development, response to light stim...
Does Knockout of Sap18 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Sap18
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Sap18 (Sin3-associated polypeptide 18) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, mRNA processing, negative regulation of DNA-templated transcription, negative regulation of mRNA splicing, via spliceosome, positive regulation of apoptotic process,...
Does Knockout of Tbx4 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,263
Knockout
Tbx4
cell proliferation
Colonic Cancer Cell Line
Gene: Tbx4 (T-box 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: angiogenesis, cell fate specification, developmental process, embryonic hindlimb morphogenesis, embryonic limb morphogenesis, embryonic lung development, limb morphogenesis, lung development, morphogenes...
Does Knockout of Cspp1 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Cspp1
cell proliferation
Mouse kidney carcinoma cell
Gene: Cspp1 (centrosome and spindle pole associated protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: positive regulation of cell division, positive regulation of cytokinesis; CC: cell projection, centriolar satellite, centrosome, ciliary basal body, cilium, cyto...
Does Knockout of Rdh16 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Rdh16
cell proliferation
Melanoma Cell Line
Gene: Rdh16 (retinol dehydrogenase 16) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 9-cis-retinoic acid biosynthetic process, androgen biosynthetic process, lipid metabolic process, positive regulation of retinoic acid biosynthetic process, retinoic acid metabolic proc...
Does Knockout of Myo1c in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Myo1c
protein/peptide distribution
myoblast cell line
Gene: Myo1c (myosin IC) Type: protein-coding Summary: This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The protein functions in int...
Does Knockout of Mbl1 in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,280
Knockout
Mbl1
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Mbl1 (mannose-binding lectin (protein A) 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: complement activation, classical pathway, complement activation, lectin pathway, defense response to Gram-positive bacterium, immune system process, innate immune response, k...
Does Knockout of Vmn2r52 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Vmn2r52
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Vmn2r52 (vomeronasal 2, receptor 52) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, signal transduction; MF: G protein-coupled receptor activity; CC: membrane, plasma membrane Pathways: UniProt: A0A3B...
Does Knockout of Lcn12 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,285
Knockout
Lcn12
cell proliferation
Mouse kidney carcinoma cell
Gene: Lcn12 (lipocalin 12) Type: protein-coding Summary: Predicted to enable retinoic acid binding activity. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human LCN12 (lipocalin 12). [provided by Alliance of Genome Resources, Jul 2025] ...
Does Knockout of B3galt1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
B3galt1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: B3galt1 (UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: galactosylceramide biosynthetic process, lipid metabolic process, oligosaccharide biosynthetic process, protein O-linked glycosylation, protein...
Does Knockout of Foxe1 in Embryonic Fibroblast Cell Line causally result in autophagy?
1
1,044
Knockout
Foxe1
autophagy
Embryonic Fibroblast Cell Line
Gene: Foxe1 (forkhead box E1) Type: protein-coding Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cranial skeletal system development and roof of mouth deve...
Does Knockout of Med14 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Med14
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Med14 (mediator complex subunit 14) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA polymerase II preinitiation complex assembly, positive regulation of DNA-templated transcription, positive regulation of transcription by RNA polymerase II, positive regulation o...
Does Knockout of Tagln in myoblast cell line causally result in protein/peptide distribution?
0
1,682
Knockout
Tagln
protein/peptide distribution
myoblast cell line
Gene: Tagln (transgelin) Type: protein-coding Summary: This gene encodes a smooth muscle cell-specific cytoskeletal protein. The encoded protein is structurally similar to calponin, an actin-binding protein. In mouse models of atherosclerosis the gene product may be involved in plaque cell and atheroscl...
Does Knockout of Enpp5 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,283
Knockout
Enpp5
cell proliferation
Mouse kidney carcinoma cell
Gene: Enpp5 (ectonucleotide pyrophosphatase/phosphodiesterase 5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell communication, nucleotide catabolic process; MF: NAD+ diphosphatase activity, dinucleotide phosphatase activity, hydrolase activity, metal ion binding, zi...
Does Knockout of Rnf185 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Rnf185
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rnf185 (ring finger protein 185) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, autophagy, cGAS/STING signaling pathway, defense response to virus, immune system process, innate immune response, positive regulation of ERAD pathway, positive regulation...
Does Knockout of Wnk4 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
1
161
Knockout
Wnk4
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Wnk4 (WNK lysine deficient protein kinase 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERK1 and ERK2 cascade, aldosterone secretion, calcium ion homeostasis, cellular response to xenobiotic stimulus, chloride transport, distal tubule morphogenesis, gene expres...
Does Knockout of Lpar1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,278
Knockout
Lpar1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Lpar1 (lysophosphatidic acid receptor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, Golgi to plasma membrane protein transport, adenylate cyclase-activating G protein-coupled receptor signaling pathway, adenylate cy...
Does Knockout of Vmn1r199 in myoblast cell line causally result in protein/peptide distribution?
0
1,680
Knockout
Vmn1r199
protein/peptide distribution
myoblast cell line
Gene: Vmn1r199 (vomeronasal 1 receptor 199) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, response to pheromone, sensory perception of chemical stimulus, signal transduction; MF: G protein-coupled receptor activity, pheromon...
Does Knockout of Rbp2 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Rbp2
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Rbp2 (retinol binding protein 2, cellular) Type: protein-coding Summary: No summary available. Gene Ontology: BP: fatty acid transport, retinoid metabolic process, triglyceride biosynthetic process; MF: binding, enzyme-substrate adaptor activity, fatty acid binding, lipid binding, molecul...
Does Knockout of Zfp763 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Zfp763
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Zfp763 (zinc finger protein 763) Type: protein-coding Summary: No summary available. Gene Ontology: BP: regulation of DNA-templated transcription, regulation of transcription by RNA polymerase II; MF: DNA binding, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA ...
Does Knockout of Cd300e in Colonic Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,267
Knockout
Cd300e
cell proliferation
Colonic Adenocarcinoma Cell Line
Gene: Cd300e (CD300E molecule) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, immune system process, regulation of innate immune response, signal transduction; MF: molecular_function, transmembrane signaling receptor activity; CC: membrane, plasma mem...
Does Knockout of Grb7 in Melanoma Cell Line causally result in protein/peptide accumulation?
0
1,839
Knockout
Grb7
protein/peptide accumulation
Melanoma Cell Line
Gene: Grb7 (growth factor receptor bound protein 7) Type: protein-coding Summary: No summary available. Gene Ontology: BP: insulin receptor signaling pathway, negative regulation of insulin receptor signaling pathway, negative regulation of translation, positive regulation of cell migration, si...
Does Knockout of Tppp in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,259
Knockout
Tppp
cell proliferation
Mouse kidney carcinoma cell
Gene: Tppp (tubulin polymerization promoting protein) Type: protein-coding Summary: No summary available. Gene Ontology: BP: astral microtubule organization, cell division, microtubule bundle formation, microtubule nucleation by microtubule organizing center, microtubule polymerization, myelin ...
Does Knockout of Nedd1 in Cytotoxic T-lymphocyte (CD8+ T cells) causally result in cell proliferation?
1
2,412
Knockout
Nedd1
cell proliferation
Cytotoxic T-lymphocyte (CD8+ T cells)
Gene: Nedd1 (neural precursor cell expressed, developmentally down-regulated gene 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell division, microtubule depolymerization, microtubule nucleation, microtubule polymerization or depolymerization, mitotic cell cycle, re...
Does Knockout of Gm773 in Embryonic Stem Cell Line causally result in cell proliferation?
0
578
Knockout
Gm773
cell proliferation
Embryonic Stem Cell Line
Gene: Gm773 (predicted gene 773) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acrosome reaction, meiotic cell cycle, penetration of zona pellucida, sperm DNA condensation, spermatid development; CC: nucleus, synaptonemal complex Pathways: UniProt: Q3...
Does Knockout of Nos2 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
Nos2
cell proliferation
Mouse kidney carcinoma cell
Gene: Nos2 (nitric oxide synthase 2, inducible) Type: protein-coding Summary: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase that is induci...
Does Knockout of Ap4b1 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
82
Knockout
Ap4b1
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Ap4b1 (adaptor-related protein complex AP-4, beta 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: intracellular protein transport, protein localization to somatodendritic compartment, protein targeting, protein transport, vesicle-mediated transport; MF: clathrin ...
Does Knockout of Got1l1 in Melanoma Cell Line causally result in cell proliferation?
0
1,270
Knockout
Got1l1
cell proliferation
Melanoma Cell Line
Gene: Got1l1 (glutamic-oxaloacetic transaminase 1-like 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: amino acid metabolic process, aspartate biosynthetic process; MF: L-aspartate:2-oxoglutarate aminotransferase activity, pyridoxal phosphate binding, transaminase acti...
Does Knockout of Wipi2 in Embryonic Fibroblast Cell Line causally result in response to virus?
0
1,133
Knockout
Wipi2
response to virus
Embryonic Fibroblast Cell Line
Gene: Wipi2 (WD repeat domain, phosphoinositide interacting 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: autophagosome assembly, autophagy, autophagy of mitochondrion, cellular response to starvation, glycophagy, nucleophagy, pexophagy, protein localization to phago...
Does Knockout of Smpd3 in Melanoma Cell Line causally result in cell proliferation?
0
1,281
Knockout
Smpd3
cell proliferation
Melanoma Cell Line
Gene: Smpd3 (sphingomyelin phosphodiesterase 3, neutral) Type: protein-coding Summary: No summary available. Gene Ontology: BP: BMP signaling pathway, DNA biosynthetic process, G1 to G0 transition, artery smooth muscle contraction, bone development, bone growth, bone mineralization, cartilage d...
Does Knockout of C130074G19Rik in Pancreatic Cancer Cell Line causally result in response to chemicals?
0
2,359
Knockout
C130074G19Rik
response to chemicals
Pancreatic Cancer Cell Line
Gene: C130074G19Rik (RIKEN cDNA C130074G19 gene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, regulation of response to drug; CC: 9+0 non-motile cilium, membrane Pathways: UniProt: Q8BGN9 Entrez ID: 226777
Does Knockout of Dclre1c in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
Dclre1c
cell proliferation
Mouse kidney carcinoma cell
Gene: Dclre1c (DNA cross-link repair 1C) Type: protein-coding Summary: This gene encodes a member of the SNM1 family of nucleases and is involved in V(D)J recombination and DNA repair. This protein has single-strand-specific 5'-3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3'...
Does Knockout of Cpt1c in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Cpt1c
protein/peptide accumulation
Mouse cell
Gene: Cpt1c (carnitine palmitoyltransferase 1c) Type: protein-coding Summary: Enables palmitoyl-(protein) hydrolase activity. Involved in regulation of postsynaptic membrane neurotransmitter receptor levels. Located in axon; dendrite; and endoplasmic reticulum. Part of AMPA glutamate receptor complex. I...
Does Knockout of Bclaf1 in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Bclaf1
cell proliferation
Regulatory T cell
Gene: Bclaf1 (BCL2-associated transcription factor 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: DNA damage response, cellular response to leukemia inhibitory factor, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcripti...
Does Knockout of Adra2b in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Adra2b
protein/peptide accumulation
Embryonic Cell Line
Gene: Adra2b (adrenergic receptor, alpha 2b) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G protein-coupled receptor signaling pathway, MAPK cascade, adrenergic receptor signaling pathway, angiogenesis, epidermal growth factor receptor signaling pathway, female pregnan...
Does Knockout of Mrpl28 in Mouse cell causally result in protein/peptide accumulation?
0
1,047
Knockout
Mrpl28
protein/peptide accumulation
Mouse cell
Gene: Mrpl28 (mitochondrial ribosomal protein L28) Type: protein-coding Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit....
Does Knockout of Smok3a in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
165
Knockout
Smok3a
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Smok3a (sperm motility kinase 3A) Type: protein-coding Summary: Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in intracellular signal transduction. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025] Gene Ontol...
Does Knockout of Syk in Embryonic Stem Cell Line causally result in cell proliferation?
0
2,477
Knockout
Syk
cell proliferation
Embryonic Stem Cell Line
Gene: Syk (spleen tyrosine kinase) Type: protein-coding Summary: Enables several functions, including ATP binding activity; SH2 domain binding activity; and enzyme binding activity. Involved in several processes, including cell surface receptor signaling pathway; myeloid cell activation involved in immu...
Does Knockout of Zfyve28 in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,287
Knockout
Zfyve28
cell proliferation
Mouse kidney carcinoma cell
Gene: Zfyve28 (zinc finger, FYVE domain containing 28) Type: protein-coding Summary: Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in negative regulation of epidermal growth factor-activated receptor activity. Predicted to be located in cytosol. Predicte...
Does Knockout of Mobp in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
81
Knockout
Mobp
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Mobp (myelin-associated oligodendrocytic basic protein) Type: protein-coding Summary: No summary available. Gene Ontology: MF: structural constituent of myelin sheath; CC: cytoplasm, cytosol, mitochondrion, myelin sheath, perinuclear region of cytoplasm Pathways: UniPro...
Does Knockout of Ush2a in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
161
Knockout
Ush2a
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Ush2a (usherin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: animal organ morphogenesis, establishment of localization in cell, establishment of protein localization, hair cell differentiation, inner ear auditory receptor cell differentiation, inner ear receptor ...
Does Knockout of Usp18 in Pre-B-Lymphocyte Cell Line causally result in cell proliferation?
0
83
Knockout
Usp18
cell proliferation
Pre-B-Lymphocyte Cell Line
Gene: Usp18 (ubiquitin specific peptidase 18) Type: protein-coding Summary: No summary available. Gene Ontology: BP: antiviral innate immune response, negative regulation of type I interferon-mediated signaling pathway, protein deubiquitination, proteolysis, regulation of inflammatory response,...
Does Knockout of Ada in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Ada
protein/peptide distribution
myoblast cell line
Gene: Ada (adenosine deaminase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: AMP catabolic process, AMP salvage, GMP salvage, IMP salvage, Peyer's patch development, T cell activation, adenosine catabolic process, adenosine metabolic process, allantoin metabolic proces...
Does Knockout of Bpgm in Regulatory T cell causally result in protein/peptide accumulation?
0
1,482
Knockout
Bpgm
protein/peptide accumulation
Regulatory T cell
Gene: Bpgm (2,3-bisphosphoglycerate mutase) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to stress, defense response to protozoan, erythrocyte development, establishment of blood-brain barrier, glycolytic process, neuroinflammatory response, nucleosid...
Does Knockout of Ubxn10 in Neuroblastoma Cell Line causally result in response to virus?
0
1,422
Knockout
Ubxn10
response to virus
Neuroblastoma Cell Line
Gene: Ubxn10 (UBX domain protein 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, cell projection organization, cilium assembly; CC: cell projection, cilium, endoplasmic reticulum, intraciliary transport particle B Pathways: UniProt: Q8...
Does Knockout of Spag6 in Embryonic Fibroblast Cell Line causally result in regulation of signal transduction phenotype?
0
167
Knockout
Spag6
regulation of signal transduction phenotype
Embryonic Fibroblast Cell Line
Gene: Spag6 (sperm associated antigen 6) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell projection organization, epithelial cilium movement involved in extracellular fluid movement, filopodium assembly, neuron projection extension, sperm axoneme assembly; CC: acroso...
Does Knockout of Prkdc in Lymphoma Cell Line causally result in response to chemicals?
0
1,540
Knockout
Prkdc
response to chemicals
Lymphoma Cell Line
Gene: Prkdc (protein kinase, DNA activated, catalytic polypeptide) Type: protein-coding Summary: No summary available. Gene Ontology: BP: B cell lineage commitment, DNA damage response, DNA repair, DNA repair-dependent chromatin remodeling, T cell differentiation in thymus, T cell lineage commi...
Does Knockout of Sulf1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
1,277
Knockout
Sulf1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Sulf1 (sulfatase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: apoptotic process, bone development, cartilage condensation, cartilage development, cell adhesion, chondrocyte development, embryonic skeletal system development, esophagus smooth muscle contraction...
Does Knockout of Hmgcs1 in myoblast cell line causally result in protein/peptide distribution?
0
1,684
Knockout
Hmgcs1
protein/peptide distribution
myoblast cell line
Gene: Hmgcs1 (3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: acetyl-CoA metabolic process, cellular response to low-density lipoprotein particle stimulus, cholesterol biosynthetic process, cholesterol biosynthetic process...
Does Knockout of Rasgrp4 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Rasgrp4
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Rasgrp4 (RAS guanyl releasing protein 4) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Ras protein signal transduction, antibacterial innate immune response, cell differentiation, immune response, phospholipase C-activating G protein-coupled receptor signaling pat...
Does Knockout of Jam3 in Regulatory T cell causally result in cell proliferation?
0
1,483
Knockout
Jam3
cell proliferation
Regulatory T cell
Gene: Jam3 (junction adhesion molecule 3) Type: protein-coding Summary: No summary available. Gene Ontology: BP: adaptive immune response, adherens junction assembly, angiogenesis, apical protein localization, cell adhesion, cell differentiation, cell migration, cell-cell adhesion, cell-matrix ...
Does Knockout of Kif3c in breast epithelium causally result in cell cycle progression?
0
1,468
Knockout
Kif3c
cell cycle progression
breast epithelium
Gene: Kif3c (kinesin family member 3C) Type: protein-coding Summary: No summary available. Gene Ontology: BP: microtubule-based movement, positive regulation of neuron projection development; MF: ATP binding, ATP hydrolysis activity, kinesin binding, microtubule binding, microtubule motor activ...
Does Knockout of Pja1 in Pancreatic Ductal Adenocarcinoma Cell Line causally result in response to chemicals?
0
2,307
Knockout
Pja1
response to chemicals
Pancreatic Ductal Adenocarcinoma Cell Line
Gene: Pja1 (praja ring finger ubiquitin ligase 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein catabolic process, protein ubiquitination; MF: metal ion binding, protein binding, transferase activity, ubiquitin protein ligase activity, zinc ion binding; CC: cyto...
Does Knockout of Vim in macrophage causally result in phagocytosis?
0
1,890
Knockout
Vim
phagocytosis
macrophage
Gene: Vim (vimentin) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Bergmann glial cell differentiation, astrocyte development, cellular response to lipopolysaccharide, cellular response to muramyl dipeptide, cellular response to type II interferon, cytoskeleton organiza...
Does Knockout of Ugt2b5 in myoblast cell line causally result in protein/peptide distribution?
1
1,685
Knockout
Ugt2b5
protein/peptide distribution
myoblast cell line
Gene: Ugt2b5 (UDP glucuronosyltransferase 2 family, polypeptide B5) Type: protein-coding Summary: No summary available. Gene Ontology: BP: estrogen metabolic process, lipid metabolic process, steroid metabolic process; MF: UDP-glycosyltransferase activity, glucuronosyltransferase activity, glyc...
Does Knockout of Gbp10 in Immortal Mouse Liver-derived Cell Line causally result in tumorigenicity?
0
687
Knockout
Gbp10
tumorigenicity
Immortal Mouse Liver-derived Cell Line
Gene: Gbp10 (guanylate-binding protein 10) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to lipopolysaccharide, cellular response to type II interferon, defense response to Gram-positive bacterium, defense response to protozoan, immune system process, ...
Does Knockout of AI182371 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,273
Knockout
AI182371
cell proliferation
Mammary Gland Tumor Cell Line
Gene: AI182371 (expressed sequence AI182371) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, complement activation, complement activation, GZMK pathway, complement activation, alternative pathway, complement activation, classical pathway, complement ac...
Does Knockout of Eif4ebp1 in Embryonic Cell Line causally result in protein/peptide accumulation?
0
2,403
Knockout
Eif4ebp1
protein/peptide accumulation
Embryonic Cell Line
Gene: Eif4ebp1 (eukaryotic translation initiation factor 4E binding protein 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: G1/S transition of mitotic cell cycle, IRES-dependent translational initiation of linear mRNA, TOR signaling, cellular response to dexamethasone ...
Does Knockout of Cdk13 in Colonic Cancer Cell Line causally result in cell proliferation?
0
2,179
Knockout
Cdk13
cell proliferation
Colonic Cancer Cell Line
Gene: Cdk13 (cyclin dependent kinase 13) Type: protein-coding Summary: No summary available. Gene Ontology: BP: RNA splicing, alternative mRNA splicing, via spliceosome, hemopoiesis, mRNA processing, negative regulation of stem cell differentiation, positive regulation of transcription by RNA p...
Does Knockout of 4930523C07Rik in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,284
Knockout
4930523C07Rik
cell proliferation
Mouse kidney carcinoma cell
Gene: 4930523C07Rik (RIKEN cDNA 4930523C07 gene) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q8CE67, E9Q2T4 Entrez ID: 67647
Does Knockout of Usp24 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,181
Knockout
Usp24
tumorigenicity
Colonic Cancer Cell Line
Gene: Usp24 (ubiquitin specific peptidase 24) Type: protein-coding Summary: No summary available. Gene Ontology: BP: protein deubiquitination, proteolysis, regulation of protein stability; MF: cysteine-type deubiquitinase activity, cysteine-type peptidase activity, hydrolase activity, peptidase...
Does Knockout of Ugt1a6a in Regulatory T cell causally result in cell proliferation?
0
1,484
Knockout
Ugt1a6a
cell proliferation
Regulatory T cell
Gene: Ugt1a6a (UDP glucuronosyltransferase 1 family, polypeptide A6A) Type: protein-coding Summary: No summary available. Gene Ontology: BP: 4-chlorobiphenyl metabolic process, L-ascorbic acid biosynthetic process, cellular response to glucocorticoid stimulus, glucuronate metabolic process, xen...
Does Knockout of Sfmbt1 in Breast Adenocarcinoma Cell Line causally result in tumorigenicity?
0
2,171
Knockout
Sfmbt1
tumorigenicity
Breast Adenocarcinoma Cell Line
Gene: Sfmbt1 (Scm-like with four mbt domains 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cell differentiation, chromatin organization, negative regulation of DNA-templated transcription, negative regulation of muscle organ development, regulation of DNA-templated t...
Does Knockout of Gpatch1 in macrophage causally result in phagocytosis?
0
1,889
Knockout
Gpatch1
phagocytosis
macrophage
Gene: Gpatch1 (G patch domain containing 1) Type: protein-coding Summary: Predicted to enable RNA binding activity. Predicted to be involved in mRNA processing. Predicted to be part of catalytic step 2 spliceosome. Predicted to be active in nucleus. Is expressed in central nervous system and sensory org...
Does Knockout of Pld1 in Microglial Cell Line causally result in protein/peptide accumulation?
0
1,399
Knockout
Pld1
protein/peptide accumulation
Microglial Cell Line
Gene: Pld1 (phospholipase D1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cellular response to nutrient, defense response to Gram-positive bacterium, intracellular signal transduction, lipid catabolic process, lipid metabolic process, phosphatidic acid biosynthetic pr...
Does Knockout of Edem2 in Colonic Cancer Cell Line causally result in cell proliferation?
0
1,276
Knockout
Edem2
cell proliferation
Colonic Cancer Cell Line
Gene: Edem2 (ER degradation enhancer, mannosidase alpha-like 2) Type: protein-coding Summary: No summary available. Gene Ontology: BP: ERAD pathway, carbohydrate metabolic process, endoplasmic reticulum mannose trimming, endoplasmic reticulum unfolded protein response, positive regulation of re...
Does Knockout of Eif2ak3 in Colonic Cancer Cell Line causally result in tumorigenicity?
0
2,180
Knockout
Eif2ak3
tumorigenicity
Colonic Cancer Cell Line
Gene: Eif2ak3 (eukaryotic translation initiation factor 2 alpha kinase 3) Type: protein-coding Summary: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation ...
Does Knockout of Ropn1l in Microglial Cell Line causally result in protein/peptide distribution?
0
1,585
Knockout
Ropn1l
protein/peptide distribution
Microglial Cell Line
Gene: Ropn1l (ropporin 1-like) Type: protein-coding Summary: No summary available. Gene Ontology: BP: cilium movement, epithelial cilium movement involved in extracellular fluid movement, flagellated sperm motility, mating, sperm capacitation; MF: identical protein binding, protein binding; CC:...
Does Knockout of Tmprss12 in Mammary Gland Tumor Cell Line causally result in cell proliferation?
0
1,274
Knockout
Tmprss12
cell proliferation
Mammary Gland Tumor Cell Line
Gene: Tmprss12 (transmembrane (C-terminal) protease, serine 12) Type: protein-coding Summary: Predicted to enable serine-type endopeptidase activity. Involved in acrosome assembly and positive regulation of sperm capacitation. Acts upstream of or within binding activity of sperm to zona pellucida and pr...
Does Knockout of 9030624G23Rik in Embryonic Cell Line causally result in protein/peptide accumulation?
0
1,440
Knockout
9030624G23Rik
protein/peptide accumulation
Embryonic Cell Line
Gene: 9030624G23Rik (RIKEN cDNA 9030624G23 gene) Type: protein-coding Summary: No summary available. Gene Ontology: BP: biological_process, regulation of DNA-templated transcription; CC: cellular_component, nucleus Pathways: UniProt: Q9D308 Entrez ID: 66808
Does Knockout of D17H6S53E in Mouse kidney carcinoma cell causally result in cell proliferation?
0
1,272
Knockout
D17H6S53E
cell proliferation
Mouse kidney carcinoma cell
Gene: D17H6S53E (DNA segment, Chr 17, human D6S53E) Type: protein-coding Summary: No summary available. Gene Ontology: Pathways: UniProt: Q9Z1R4 Entrez ID: 114585
Does Knockout of Cacna1f in breast epithelium causally result in cell cycle progression?
0
1,469
Knockout
Cacna1f
cell cycle progression
breast epithelium
Gene: Cacna1f (calcium channel, voltage-dependent, alpha 1F subunit) Type: protein-coding Summary: Enables voltage-gated calcium channel activity. Acts upstream of or within several processes, including intracellular calcium ion homeostasis; neuron projection morphogenesis; and visual perception. Predic...
Does Knockout of Nle1 in Breast Adenocarcinoma Cell Line causally result in cell proliferation?
0
2,173
Knockout
Nle1
cell proliferation
Breast Adenocarcinoma Cell Line
Gene: Nle1 (notchless homolog 1) Type: protein-coding Summary: No summary available. Gene Ontology: BP: Notch signaling pathway, hematopoietic stem cell homeostasis, inner cell mass cell differentiation, kidney development, negative regulation of mitotic cell cycle, positive regulation of canon...