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Toward an integrated approach to crop production and pollination ecology through the application of remote sensing. | Insect pollinators provide an essential ecosystem service by transferring pollen to crops and native vegetation. The extent to which pollinator communities vary both spatially and temporally has important implications for ecology, conservation and agricultural production. However, understanding the complex interactions... | 10.7717/peerj.5806 | 30,364,410 | PeerJ | 2,018 | ||
Anti-allergic and anti-inflammatory effects of resveratrol via inhibiting TXNIP-oxidative stress pathway in a mouse model of allergic rhinitis. | BACKGROUND
Allergic rhinitis (AR) is a type I hypersensitivity mediated by IgE in the nose. Thioredoxin-interacting protein (TXNIP) plays a pivotal role in the process of producing reactive oxygen species (ROS). Resveratrol is a TXNIP inhibitor. Nonetheless, its role and mechanism in AR are still undetermined. The pres... | 10.1016/j.waojou.2020.100473 | 33,133,334 | The World Allergy Organization journal | 2,020 | ||
[Maintenance therapy with low doses of clozapine in schizophrenia]. | A sample of 27 schizophrenic outpatients, who were or had been in maintenance therapy with clozapine, were studied for the last 2 years, in an open clinical trial. Two groups were followed: group 1-with low maintenance doses of clozapine, and with a concomitant neuroleptic therapy, and group 2-where clozapine was switc... | 8,657,050 | D000293:Adolescent; D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents; D003024:Clozapine; D006801:Humans; D008875:Middle Aged; D012559:Schizophrenia | Medicinski pregled | 1,995 | D014150:Antipsychotic Agents; D003024:Clozapine | |
Pharmacogenetics of Lethal Opioid Overdose: Review of Current Evidence and Preliminary Results from a Pilot Study. | There has been a worldwide substantial increase in accidental opioid-overdose deaths. The aim of this review, along with preliminary results from our pilot study, is to highlight the use of pharmacogenetics as a tool to predict causes of accidental opioid-overdose death. For this review, a systematic literature search ... | 10.3390/jpm13060918 | 37,373,907 | Journal of personalized medicine | 2,023 | ||
Effects of maturational agents on expression and secretion of two partially characterized high molecular weight milk-related glycoproteins in MCF-7 breast carcinoma cells. | We have previously defined a human mammary epithelial antigen using a murine monoclonal antibody (MAb), designated DF3, prepared against a membrane-enriched fraction of a human breast carcinoma. MAb DF3 detects a cell surface antigen with a molecular weight (mw) of approximately 300 Kd and a higher mw species also dete... | 10.1002/jcp.1041260117 | 2,418,036 | D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D001943:Breast Neoplasms; D002454:Cell Differentiation; D002460:Cell Line; D003429:Cross Reactions; D003561:Cytarabine; D005260:Female; D006023:Glycoproteins; D006801:Humans; D008715:Methionine; D008894:Milk Proteins; D008970:Molecular Weight; D009439:Neuramin... | Journal of cellular physiology | 1,986 | D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D006023:Glycoproteins; D008894:Milk Proteins; D003561:Cytarabine; D012313:RNA; D008715:Methionine; D009439:Neuraminidase; D013755:Tetradecanoylphorbol Acetate |
Measures of individual and group changes in ordered categorical data: application to the ADL staircase. | The aim was to describe the application of a non-parametric method to a study of changes in activities of daily living (ADL) measured by a 10-level ordinal scale, the Staircase of ADL, in a population of 70-year-old persons followed to the age of 76 (n = 371). The statistical method takes account of the fact that chang... | 9,428,057 | D000203:Activities of Daily Living; D000368:Aged; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D008297:Male; D012372:ROC Curve; D018709:Statistics, Nonparametric | Scandinavian journal of rehabilitation medicine | 1,997 | ||
Quantitative Serum Proteomic Study Reveals that Fibrinogen-Related Proteins May Participate in the Pathophysiological Process of Simple Febrile Convulsion. | Simple febrile convulsion (SFC) is a common disease that is mainly caused by fever from extracranial infections. In this study, we used proteomic approaches involving discovery and validation cohorts to examine the proteomes of serum from children who were diagnosed with SFC, children with fever but without convulsion,... | 10.1021/jasms.9b00100 | 32,126,779 | D015415:Biomarkers; D001798:Blood Proteins; D002675:Child, Preschool; D005260:Female; D005340:Fibrinogen; D006801:Humans; D007223:Infant; D008297:Male; D013058:Mass Spectrometry; D060066:Protein Interaction Maps; D040901:Proteomics; D003294:Seizures, Febrile | Journal of the American Society for Mass Spectrometry | 2,020 | D015415:Biomarkers; D001798:Blood Proteins; D005340:Fibrinogen |
Pharmacokinetics of an active cadralazine metabolite in plasma and blood vessels of spontaneously hypertensive rats. | The plasma and blood vessel (aorta and mesenteric artery) levels of (+/-)-6-[ethyl(2-hydroxypropyl)amino]-3-hydrazinopyridazine (ISF-2405), an active metabolite of cadralazine, were determined and compared with the changes in blood pressure in spontaneously hypertensive rats after single oral administration of cadralaz... | 3,370,071 | D000818:Animals; D001794:Blood Pressure; D001808:Blood Vessels; D006207:Half-Life; D008297:Male; D011724:Pyridazines; D051381:Rats; D011918:Rats, Inbred SHR; D014665:Vasodilator Agents | Arzneimittel-Forschung | 1,988 | D011724:Pyridazines; D014665:Vasodilator Agents; C055809:ISF 2405; C031877:cadralazine | |
Effects of the level of household access to water, sanitation and hygiene on the nutritional status of children under five, Benin. | BACKGROUND
Whether or not the Water, Sanitation and Hygiene (WASH) conditions in which children under five live determine their nutritional status is still under discussion. The work aimed to study the effects of household WASH conditions to which children under five are exposed on their nutritional status in Benin.
... | 10.1186/s40795-023-00751-8 | 37,528,455 | BMC nutrition | 2,023 | ||
[Feeding preferences in 3 species of Triatominae (Hemiptera: Reduviidae) in experimental conditions]. | Feeding preferences of three species of triatomines (Triatoma infestans, T. dimidiata, and Rhodnius prolixus) on four vertebrate hosts (opposum, dog, chicken and toad) were studied in a specially designed cage during daylight (2 hours) and at night (14 hours). T. infestans and R. prolixus remained close to the host aft... | 6,763,728 | D000818:Animals; D001835:Body Weight; D005247:Feeding Behavior; D014225:Triatominae | Revista de biologia tropical | 1,982 | ||
The Right to Food and the Planetary Boundaries framework. | The 'Right to Food' is a legal entitlement owed to all human beings established in international law more than half a century ago. Fulfilment of the right has been entrusted to states parties to the 1966 International Covenant on Economic, Social and Cultural Rights (ICESCR). However, in practice, the right is often br... | 10.3184/003685017X14858552487427 | 28,693,670 | D003906:Developing Countries; D005260:Female; D005523:Food Supply; D006806:Human Rights; D006801:Humans | Science progress | 2,017 | |
CAPABLE: A Scoring System Utilizing Patient-Reported Measures to Evaluate Patient Experience After Mohs Surgery. | BACKGROUND
Patient experience metrics are gaining prominence in health care. We introduce the CAPABLE survey to assess postoperative experiences of Mohs surgery patients.
OBJECTIVE
We sought to determine whether CAPABLE scores aligned with overall patient satisfaction in Mohs surgery.
METHODS
This was a cross-secti... | 10.1097/DSS.0000000000003997 | 38,048,185 | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] | 2,023 | ||
Comparison of the fed and fasting states on the absorption of melphalan in multiple myeloma. | Melphalan absorption was studied over three consecutive days in five patients with multiple myeloma. On 1 day melphalan (approximately 7 mg/m2 = 10-12 mg) was administered IV, on 1 day PO fasting, and on 1 day PO after a standard breakfast. The order was different for each patient to minimise trends that might affect a... | 10.1007/BF00256542 | 6,705,135 | D000042:Absorption; D000368:Aged; D004435:Eating; D005215:Fasting; D005260:Female; D006801:Humans; D008297:Male; D008558:Melphalan; D008875:Middle Aged; D009101:Multiple Myeloma; D013997:Time Factors | Cancer chemotherapy and pharmacology | 1,984 | D008558:Melphalan |
Requirement of cell proliferation for the initiation of liver carcinogenesis as assayed by three different procedures. | Experiments were designed to determine the role of cell proliferation in the initiation of liver carcinogenesis induced by chemicals. To investigate this, two methylating carcinogens, N-methyl-N-nitrosourea and 1,2-dimethylhydrazine, were used as the initiating carcinogens. The initiated hepatocytes were monitored by s... | 6,113,048 | D000818:Animals; D002455:Cell Division; D004032:Diet; D004127:Dimethylhydrazines; D006498:Hepatectomy; D008114:Liver Neoplasms, Experimental; D008297:Male; D008770:Methylnitrosourea; D011230:Precancerous Conditions; D051381:Rats; D013997:Time Factors; D005723:gamma-Glutamyltransferase | Cancer research | 1,981 | D004127:Dimethylhydrazines; D008770:Methylnitrosourea; D005723:gamma-Glutamyltransferase | |
Olfactory epithelium in young adult and aging rats as seen with high-resolution scanning electron microscopy. | The present study uses mainly scanning electron microscopy to demonstrate the three-dimensional internal cell structures of rat olfactory epithelial cells. The aldehyde-prefixed osmium-DMSO-osmium (AODO) method devised by Tanaka and Mitsushima (1984) was applied to the present study to disclose intracellular structures... | 10.1002/jemt.1070230106 | 1,392,072 | D000375:Aging; D000818:Animals; D002923:Cilia; D003712:Dendrites; D008855:Microscopy, Electron, Scanning; D009831:Olfactory Mucosa; D051381:Rats; D017208:Rats, Wistar; D011984:Sensory Receptor Cells | Microscopy research and technique | 1,992 | |
Phase I/pharmacokinetic study of the topoisomerase I inhibitor GG211 administered as a 21-day continuous infusion. | BACKGROUND
Preclinical results support a prolonged schedule of administration for topoisomerase I inhibitors, and we have previously demonstrated the safety and activity of the novel water-soluble topoisomerase I inhibitor GG211 when given as a 72-hour continuous infusion to cancer patients.
PATIENTS AND METHODS
In a... | 10.1023/a:1008313011289 | 10,355,580 | D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents; D002166:Camptothecin; D015331:Cohort Studies; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009369:Neoplasms; D016896:Treatmen... | Annals of oncology : official journal of the European Society for Medical Oncology | 1,999 | D000970:Antineoplastic Agents; C091719:lurtotecan; D002166:Camptothecin |
Studies on the osmophilic fungus Wallemia sebi as an allergen evaluated by skin prick test and radioallergosorbent test. | Recently, Wallemia sebi, a species of osmophilic fungi, has been abundantly detected in house dust using low water activity media. In this study, allergenic activity of W. sebi was assessed by skin prick test and radioallergosorbent test (RAST) in 74 asthmatic patients ranging from 6 to 32 years of age. Aspergillus fum... | 10.1159/000235055 | 2,613,343 | D000293:Adolescent; D000328:Adult; D000485:Allergens; D000946:Antigens, Fungal; D001230:Aspergillus; D001249:Asthma; D002648:Child; D004391:Dust; D005658:Fungi; D006801:Humans; D011852:Radioallergosorbent Test; D012882:Skin Tests | International archives of allergy and applied immunology | 1,989 | D000485:Allergens; D000946:Antigens, Fungal; D004391:Dust |
Octreotide (SMS 201-995) inhibits the growth of colon peritoneal carcinomatosis in BDIX rats. | In order to assess the effect of octreotide, a somatostatin analogue, on the growth of colon peritoneal carcinomatosis, 20 BDIX rats were injected i.p. with 1 x 10(6) colon cancer cells (DHD/K12 tumor cell line) and received octreotide, 65 micrograms/kg s.c. every 12 h (n = 10) or saline (n = 10) for 42 days, starting ... | 10.1016/0167-0115(93)90148-2 | 8,441,819 | D000595:Amino Acid Sequence; D000818:Animals; D002277:Carcinoma; D002455:Cell Division; D003110:Colonic Neoplasms; D005260:Female; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D008969:Molecular Sequence Data; D015282:Octreotide; D010534:Peritoneal Neoplasms; D051381:Rats; D017481:Receptors, Somatostatin; D... | Regulatory peptides | 1,993 | D017481:Receptors, Somatostatin; D015282:Octreotide |
[Metabolic adaptation resources of organism to studying at medical university students in European North]. | BACKGROUND
A student studying is accompanied with psychoemotional stress that requires functional changes in metabolic systems. A blood leucocytes enzyme activity indexes that provides an adaptation are the indicators of energy metabolism.
OBJECTIVE
The aim of investigation is to determine the features and role of me... | 25,971,132 | D000222:Adaptation, Physiological; D004734:Energy Metabolism; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008297:Male; D010088:Oxidoreductases; D010744:Phosphoric Monoester Hydrolases; D012426:Russia; D012577:Schools, Medical; D012621:Seasons; D013315:Stress, Psychological; D013334:Students; D05581... | Vestnik Rossiiskoi akademii meditsinskikh nauk | 2,014 | D010088:Oxidoreductases; D010744:Phosphoric Monoester Hydrolases | |
A Comprehensive Review of Neuropsychologic Studies Supports the Concept That Adequate Folinic Acid Rescue Prevents Post Methotrexate Neurotoxicity. | PURPOSE
To review all studies providing evidence of the correlation between folinic acid (FA) rescue inadequacy and long-term cognitive damage in neuropsychological studies of children with acute lymphoblastic leukemia or osteogenic sarcoma treated under protocols using high-dose methotrexate and FA rescue.
METHODS
A... | 10.1097/MPH.0000000000002604 | 36,598,958 | D002648:Child; D006801:Humans; D001859:Bone Neoplasms; D002955:Leucovorin; D008727:Methotrexate; D020258:Neurotoxicity Syndromes; D012516:Osteosarcoma; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma | Journal of pediatric hematology/oncology | 2,023 | D002955:Leucovorin; D008727:Methotrexate |
Title: Serious COVID-19 may have a causal relationship with myocardial injury: A Mendelian randomization study. | Background: The association of coronavirus disease 2019 (COVID-19) with myocardial injury is not well known. This study explored the association between them using the Mendelian randomization (MR) method. Method: We obtained summary data from genome-wide association studies (GWAS) on myocardial injury and COVID-19 from... | 10.3389/fgene.2023.1135887 | 37,035,726 | Frontiers in genetics | 2,023 | ||
From Viruses to Genes to Cells. | I always loved biology and to do experiments. This passion and a great deal of good fortune and serendipity landed me in the field of retrovirology at the time when it opened to experimental analysis. I became involved in viral replication, genetics, and viral oncogenes. In more recent years, I have applied what I lear... | 10.1146/annurev-virology-092818-015828 | 31,567,064 | D005858:Germany; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D009857:Oncogenes; D009858:Oncogenic Viruses; D012190:Retroviridae; D014481:United States; D014780:Viruses | Annual review of virology | 2,019 | |
Knockdown of neuropeptide Y in the dorsomedial hypothalamus reverses high-fat diet-induced obesity and impaired glucose tolerance in rats. | Neuropeptide Y (NPY) in the dorsomedial hypothalamus (DMH) plays an important role in the regulation of energy balance. While DMH NPY overexpression causes hyperphagia and obesity in rats, knockdown of NPY in the DMH via adeno-associated virus (AAV)-mediated RNAi (AAVshNPY) ameliorates these alterations. Whether this k... | 10.1152/ajpregu.00174.2015 | 26,561,644 | D050154:Adiposity; D000818:Animals; D001786:Blood Glucose; D001835:Body Weight; D000229:Dependovirus; D059305:Diet, High-Fat; D004195:Disease Models, Animal; D015536:Down-Regulation; D004435:Eating; D004734:Energy Metabolism; D055785:Gene Knockdown Techniques; D005822:Genetic Vectors; D018149:Glucose Intolerance; D0070... | American journal of physiology. Regulatory, integrative and comparative physiology | 2,016 | D001786:Blood Glucose; D007328:Insulin; D009478:Neuropeptide Y; D034741:RNA, Small Interfering |
Radiation and smoking effects on lung cancer incidence among atomic bomb survivors. | While radiation increases the risk of lung cancer among members of the Life Span Study (LSS) cohort of atomic bomb survivors, there are still important questions about the nature of its interaction with smoking, the predominant cause of lung cancer. Among 105,404 LSS subjects, 1,803 primary lung cancer incident cases w... | 10.1667/RR2083.1 | 20,681,801 | D003043:Cocarcinogenesis; D015331:Cohort Studies; D005260:Female; D006801:Humans; D015994:Incidence; D007564:Japan; D008175:Lung Neoplasms; D008297:Male; D008962:Models, Theoretical; D009689:Nuclear Warfare; D011829:Radiation Dosage; D012907:Smoking | Radiation research | 2,010 | |
Double deuterated acetylacetone in neon matrices: infrared spectroscopy, photoreactivity and the tunneling process. | The effect of deuteration of acetylacetone (C5O2H8) is explored by means of IR spectroscopy of its single and double deuterated isotopologues trapped in neon matrices. The whole vibrational spectra of chelated enols are very sensitive to the H-D exchange of the hydrogen atom involved in the internal hydrogen bond. UV e... | 10.1039/c6cp02796b | 27,412,624 | Physical chemistry chemical physics : PCCP | 2,016 | ||
Global Incidence and mortality of oesophageal cancer and their correlation with socioeconomic indicators temporal patterns and trends in 41 countries. | Oesophageal cancers (adenocarcinomas [AC] and squamous cell carcinomas [SCC]) are characterized by high incidence/mortality in many countries. We aimed to delineate its global incidence and mortality, and studied whether socioeconomic development and its incidence rate were correlated. The age-standardized rates (ASRs)... | 10.1038/s41598-018-19819-8 | 29,540,708 | D004938:Esophageal Neoplasms; D014943:Global Health; D006801:Humans; D015994:Incidence; D009026:Mortality; D012959:Socioeconomic Factors; D062211:Spatio-Temporal Analysis | Scientific reports | 2,018 | |
Theory of mind and the brain in anorexia nervosa: relation to treatment outcome. | OBJECTIVE
Converging evidence suggests deficits in theory-of-mind (ToM) processing in patients with anorexia nervosa (AN). The present study aimed at elucidating the neural mechanisms underlying ToM-deficits in AN.
METHOD
A total of 19 adolescent patients with AN and 21 age-matched controls were investigated using fu... | 10.1016/j.jaac.2012.06.007 | 22,840,554 | D000293:Adolescent; D000856:Anorexia Nervosa; D001828:Body Image; D015992:Body Mass Index; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D005500:Follow-Up Studies; D059907:Functional Neuroimaging; D006760:Hospitalization; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male;... | Journal of the American Academy of Child and Adolescent Psychiatry | 2,012 | |
Circulating vascular endothelial growth factor in cutaneous malignant melanoma. | BACKGROUND
Angiogenesis has been reported as a parameter of potential prognostic value in solid tumours, as it may facilitate tumour growth and metastasis. One of the most important growth factors involved in angiogenesis is vascular endothelial growth factor (VEGF).
OBJECTIVES
To determine the predictive value of ci... | 10.1111/j.1365-2133.2005.06507.x | 15,840,099 | D018450:Disease Progression; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma; D009363:Neoplasm Proteins; D009367:Neoplasm Staging; D009389:Neovascularization, Pathologic; D011379:Prognosis; D011446:Prospective Studies; D012878:Skin Neoplasms; D042461:Vascular Endothelial Growth Factor A | The British journal of dermatology | 2,005 | D009363:Neoplasm Proteins; D042461:Vascular Endothelial Growth Factor A |
Easily Processable Thermosets with Outstanding Performance via Smart Twisted Small-Molecule Benzoxazines. | High-performance aromatic polymers have excellent thermal, mechanical, and electrical properties and are lightweight, but it is highly challenging to deliver outstanding performances while still maintaining good processability of the precursors. Here, a new family of small-molecule benzoxazine resins with ortho-maleimi... | 10.1002/marc.201900625 | 31,958,211 | D048588:Benzoxazines; D002616:Chemical Engineering; D008301:Maleimides; D008422:Materials Testing; D008968:Molecular Conformation; D058105:Polymerization; D011108:Polymers; D013696:Temperature | Macromolecular rapid communications | 2,020 | D048588:Benzoxazines; D008301:Maleimides; D011108:Polymers; C043592:maleimide |
Primary ornithine transcarbamylase deficiency. A case report and electron microscopic study. | Histological and ultrastructural findings obtained upon examination of a liver biopsy specimen from a 2-year-old girl with primary ornithine transcarbamylase (OTC) deficiency are presented. The OTC activity in the hepatic tissue of the patient was 7% that of the normal level. Light microscopic observation showed diffus... | 10.1111/j.1440-1827.1989.tb02461.x | 2,678,891 | D002675:Child, Preschool; D005260:Female; D006801:Humans; D008107:Liver Diseases; D008297:Male; D008930:Mitochondria, Liver; D009954:Ornithine Carbamoyltransferase; D020163:Ornithine Carbamoyltransferase Deficiency Disease | Acta pathologica japonica | 1,989 | D009954:Ornithine Carbamoyltransferase |
Early pregnancy ultrasound measurements and prediction of first trimester pregnancy loss: A logistic model. | Our objective was to prospectively validate the use of gestational sac (GS), yolk sac (YS) diameter, crown-rump length (CRL), and embryonal heart rate (HR) dimensions to identify early pregnancy loss. This was a prospective cohort study of first trimester pregnancies. GS and YS diameter, CRL, and HR measurements were s... | 10.1038/s41598-020-58114-3 | 32,005,925 | D000022:Abortion, Spontaneous; D015331:Cohort Studies; D003376:Counseling; D005260:Female; D058746:Gestational Sac; D006801:Humans; D016015:Logistic Models; D009929:Organ Size; D011247:Pregnancy; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First; D011379:Prognosis; D011446:Prospective Studies; D016216:Ultra... | Scientific reports | 2,020 | |
The Non-Coding RNA GAS5 and Its Role in Tumor Therapy-Induced Resistance. | The growth arrest-specific transcript 5 (GAS5) is a >200-nt lncRNA molecule that regulates several cellular functions, including proliferation, apoptosis, invasion and metastasis, across different types of human cancers. Here, we reviewed the current literature on the expression of GAS5 in leukemia, cervical, breast, o... | 10.3390/ijms21207633 | 33,076,450 | D000818:Animals; D019008:Drug Resistance, Neoplasm; D016147:Genes, Tumor Suppressor; D006801:Humans; D035683:MicroRNAs; D009369:Neoplasms; D062085:RNA, Long Noncoding | International journal of molecular sciences | 2,020 | C561567:GAS5 long non-coding RNA, human; D035683:MicroRNAs; D062085:RNA, Long Noncoding |
Construction of direct Z-Scheme photocatalysts for overall water splitting using two-dimensional van der waals heterojunctions of metal dichalcogenides. | The direct Z-scheme system constructed by two-dimensional (2D) materials is an efficient route for hydrogen production from photocatalytic water splitting. In the present work, the 2D van der Waals (vdW) heterojunctions of MoSe2 /SnS2 , MoSe2 /SnSe2 , MoSe2 /CrS2 , MoTe2 /SnS2 , MoTe2 /SnSe2 , and MoTe2 /CrS2 are propo... | 10.1002/jcc.25540 | 30,431,652 | Journal of computational chemistry | 2,019 | ||
Immunoglobulin GM Genes, Cytomegalovirus Immunoevasion, and the Risk of Glioma, Neuroblastoma, and Breast Cancer. | Human cytomegalovirus (HCMV), a common herpes virus, has been reported to be a risk factor for many diseases, including malignant diseases such as glioma, neuroblastoma, and breast cancer. Some of the HCMV-associated diseases (e.g., glioma) are rare. The question arises: how could a common virus be associated with unco... | 10.3389/fonc.2014.00236 | 25,221,749 | Frontiers in oncology | 2,014 | ||
JICE goes "social". | Social media is transforming health care. The Journal of Interventional Cardiac Electrophysiology (JICE) has launched its own social media presence and is now on Facebook. JICE will post each issue's table of contents, special articles, online-first publications to allow real-time notifications to JICE's readers and fa... | 10.1007/s10840-011-9621-x | 21,972,151 | D054849:Cardiac Electrophysiology; D005544:Forecasting; D006801:Humans; D020407:Internet; D010506:Periodicals as Topic; D061108:Social Media | Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing | 2,011 | |
Heterotransplantation studies with tissue culture cell lines in various animal and in vitro host systems. | The human amnion cell line FL was found to be more tumorigenic than HeLa cells when used as a positive control in heterotransplantation assays. FL cells formed significantly larger locally invasive tumors than HeLa cells in both Balb/c/nu/nu mice and ATG-treated newborn Wistar rats. In addition, FL cells resulted in me... | 10.1016/s0092-1157(85)80028-7 | 3,886,663 | D000818:Animals; D000831:Animals, Newborn; D002460:Cell Line; D002642:Chick Embryo; D046508:Culture Techniques; D005260:Female; D006801:Humans; D008175:Lung Neoplasms; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D009362:Neoplasm Metastasis; D009368:Neoplasm Transplantation; D009924:Organ Culture Tech... | Journal of biological standardization | 1,985 | |
Rat neocortical slice preparation for electrophysiological and pharmacological studies. | A procedure for the preparation and maintenance of rat neocortical slices for in vitro electrophysiological and pharmacological studies is described. Application of L-glutamate increased the spontaneous firing rate of the cells in these slices. Acetylcholine (ACh) slightly elevated the firing in some cells, while showi... | 10.1016/0160-5402(84)90036-6 | 6,145,816 | D000109:Acetylcholine; D000818:Animals; D002540:Cerebral Cortex; D004594:Electrophysiology; D005033:Ethylmaleimide; D005971:Glutamates; D018698:Glutamic Acid; D066298:In Vitro Techniques; D008297:Male; D010477:Perfusion; D051381:Rats; D011919:Rats, Inbred Strains | Journal of pharmacological methods | 1,984 | D005971:Glutamates; D018698:Glutamic Acid; D000109:Acetylcholine; D005033:Ethylmaleimide |
Gene expression during mammalian spermatogenesis. II. Evidence for stage-specific differences in mRNA populations. | Gene expression during murine spermatogenesis has been studied using highly enriched populations of cells obtained by velocity sedimentation at unit gravity and further purified by density gradient centrifugation through Percoll. Polypeptides whose synthesis was directed by total cytoplasmic RNA from round spermatids, ... | 10.1002/jez.1402250115 | 6,187,891 | D000818:Animals; D002469:Cell Separation; D004591:Electrophoresis, Polyacrylamide Gel; D005786:Gene Expression Regulation; D008297:Male; D051379:Mice; D010452:Peptide Biosynthesis; D011061:Poly A; D011132:Polyribosomes; D012313:RNA; D012333:RNA, Messenger; D013091:Spermatogenesis; D013737:Testis | The Journal of experimental zoology | 1,983 | D012333:RNA, Messenger; D011061:Poly A; D012313:RNA |
Retinopathy and macro-albuminuria in type 2 diabetic patients. | OBJECTIVE
To identify the correlation between the development of retinopathy and macro-albuminuria and the other risk factors for the retinopathy in type 2 diabetic patients.
MATERIAL AND METHOD
This is a cross-sectional study. The authors studied 201 patients suffering from diabetes type 2. Fundoscopy was performed ... | 17,487,122 | D000418:Albumins; D000419:Albuminuria; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2; D003930:Diabetic Retinopathy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors | Journal of the Medical Association of Thailand = Chotmaihet thangphaet | 2,007 | D000418:Albumins | |
Nasopharyngeal flora in children with acute otitis media before and after implementation of 7 valent pneumococcal conjugate vaccine in France. | BACKGROUND
Several studies have investigated the impact of 7-valent pneumococcal conjugate vaccine (PCV7) on pneumococcal (Sp) and staphylococcal (Sa) nasopharyngeal (NP) carriage. Few have investigated the impact on Haemophilus influenzae (Hi) and Moraxella catarrhalis (Mc) carriage. We aimed to compare the NP carriag... | 10.1186/1471-2334-12-52 | 22,397,629 | D058448:Biota; D002353:Carrier State; D002675:Child, Preschool; D005260:Female; D005602:France; D006193:Haemophilus influenzae; D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D006801:Humans; D007223:Infant; D008297:Male; D001936:Moraxella catarrhalis; D009305:Nasopharynx; D010033:Otitis Media; D022242:Pneumococ... | BMC infectious diseases | 2,012 | D000069443:Heptavalent Pneumococcal Conjugate Vaccine; D022242:Pneumococcal Vaccines |
Black Deaths Matter: Race, Relationship Loss, and Effects on Survivors. | Close relationships are a resource for mental and physical health that, like other social resources, is unequally distributed in the population. This article focuses on racial disparities in the loss of relationships across the life course. Racial disparities in life expectancy in the United States mean that black Amer... | 10.1177/0022146517739317 | 29,172,766 | D001741:Black or African American; D001601:Bereavement; D003643:Death; D005190:Family; D005260:Female; D006801:Humans; D007398:Interpersonal Relations; D063505:Racism; D012959:Socioeconomic Factors; D013315:Stress, Psychological; D017741:Survivors | Journal of health and social behavior | 2,017 | |
[The clinico-psychopathological aspects of chronic depressions]. | Study of the clinical and psychopathological features of depressions in 40 inpatients, whose states corresponded to the criteria of chronic depressive disorders as described in different papers and classifications, including ICD-10 and DSM-III-R, made it possible to distinguish two types of staged development of chroni... | 8,048,311 | D000208:Acute Disease; D000328:Adult; D000368:Aged; D000375:Aging; D002908:Chronic Disease; D003866:Depressive Disorder; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011599:Psychopathology | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova | 1,993 | ||
Measuring physician practice, preparedness and preferences for genomic medicine: a national survey. | OBJECTIVE
Even as genomic medicine is implemented globally, there remains a lack of rigorous, national assessments of physicians' current genomic practice and continuing genomics education needs. The aim of this study was to address this gap.
DESIGN
A cross-sectional survey, informed by qualitative data and behaviour... | 10.1136/bmjopen-2020-044408 | 34,244,249 | D001315:Australia; D003430:Cross-Sectional Studies; D023281:Genomics; D006801:Humans; D008511:Medicine; D010820:Physicians | BMJ open | 2,021 | |
A rare case report of lead encephalopathy due to high blood lead level. | Here we report a case of lead poisoning having a serum lead level of 412 mcg dL-1 who presented with decreasing level of consciousness and recurrent seizures. He responded well to treatment with chelation therapy. | 10.1002/ccr3.7663 | 37,415,586 | Clinical case reports | 2,023 | ||
Linear scaling perturbative triples correction approximations for open-shell domain-based local pair natural orbital coupled cluster singles and doubles theory [DLPNO-CCSD(T0/T)]. | The coupled cluster method with single-, double-, and perturbative triple excitations [CCSD(T)] is considered to be one of the most reliable quantum chemistry theories. However, the steep scaling of CCSD(T) has limited its application to small or medium-sized systems for a long time. In our previous work, the linear sc... | 10.1063/1.5127550 | 31,941,297 | The Journal of chemical physics | 2,020 | ||
[Massive transfusion with the Rapid Infusion System. Its effect on core body temperature]. | Extensive blood loss requires adequate volume replacement. However the infused volume cannot be adequately warmed especially when high infusion rates are necessary. Subsequently, hypothermia develops and results in hemodynamic instability and coagulopathy. The Rapid Infusion System (RIS) allows high infusion rates (up ... | 10.1007/s00101-001-0244-y | 11,824,076 | D000328:Adult; D001778:Blood Coagulation Disorders; D016063:Blood Loss, Surgical; D001803:Blood Transfusion; D001810:Blood Volume; D001831:Body Temperature; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007035:Hypothermia; D008297:Male; D008875:Middle Aged; D017694:Rewarming; D065227:Transfusion Reaction; D014... | Der Anaesthesist | 2,001 | |
[Long-term examinations of fundic mucosa in gastroduodenal ulcer after SpV and pyloroplasty (author's transl)]. | Morphological examinations of the fundic mucosa with quantitative analysis of the parietal, chief and mucous neck cells were carried out with duodenal ulcer cases before selective proximal vagotomy and pyloroplasty, and over a period of more than four years after the operation. In the material removed by forceps biopsy... | 629,065 | D000328:Adult; D000368:Aged; D004381:Duodenal Ulcer; D005260:Female; D005500:Follow-Up Studies; D005753:Gastric Mucosa; D006801:Humans; D007413:Intestinal Mucosa; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer; D011708:Pylorus; D013276:Stomach Ulcer; D013997:Time Factors; D014628:Vagotomy | Zeitschrift fur Gastroenterologie | 1,978 | ||
[Efficacy of the pasteur oven as sterilization equipment in dental offices]. | This study was aimed at assessing the efficacy of the use of the Pasteur oven as sterilization equipment in dental offices through biological monitoring. For this assessment were taken into account how adequately the material is loaded into the equipment; time/temperature used; and preventive maintenance of the oven. T... | 10.1590/s0080-62342008000100021 | 18,450,161 | D003770:Dental Offices; D019552:Infection Control, Dental; D013242:Sterilization | Revista da Escola de Enfermagem da U S P | 2,008 | |
Endothelial toxicity of ceftazidime in anterior chamber irrigation solution. | Due to the high toxicity of aminoglycoside antibiotics, many authors prefer to use third generation cephalosporines in the prophylaxis and treatment of intraocular infections. The aim of the present study was to determine safe ceftazidime levels in anterior chamber irrigation solution. Twenty-two eyes of 12 white New Z... | 10.1006/exer.1996.0167 | 9,068,380 | D000818:Animals; D002442:Ceftazidime; D002511:Cephalosporins; D004305:Dose-Response Relationship, Drug; D009877:Endophthalmitis; D004728:Endothelium, Corneal; D013508:Ophthalmologic Surgical Procedures; D011183:Postoperative Complications; D011817:Rabbits; D016622:Silver Staining; D007507:Therapeutic Irrigation; D01494... | Experimental eye research | 1,996 | D002511:Cephalosporins; D002442:Ceftazidime |
Regulation of expression of the cyclic nucleotide phosphodiesterase gene in phosphodiesterase inhibitor-negative mutants of Dictyostelium discoideum. | During early development of Dictyostelium discoideum, the enzyme cyclic nucleotide phosphodiesterase (PD) is produced at a low rate during the period its specific inhibitor (PDI) is being synthesized. In addition, PD gene expression is derepressed in the aggregation-deficient (Agg-), Pdi- mutant HC35. These observation... | 10.1139/o94-033 | 7,840,943 | D015105:3',5'-Cyclic-AMP Phosphodiesterases; D000818:Animals; D000242:Cyclic AMP; D004023:Dictyostelium; D005786:Gene Expression Regulation; D005816:Genetic Complementation Test; D009154:Mutation; D010641:Phenotype; D010726:Phosphodiesterase Inhibitors; D012333:RNA, Messenger | Biochemistry and cell biology = Biochimie et biologie cellulaire | 1,994 | D010726:Phosphodiesterase Inhibitors; D012333:RNA, Messenger; D000242:Cyclic AMP; D015105:3',5'-Cyclic-AMP Phosphodiesterases |
Licochalcone B Extracted from Glycyrrhiza uralensis Fisch Induces Apoptotic Effects in Human Hepatoma Cell HepG2. | The present study explored the molecular mechanism by which licochalcone B induces the cell cycle arrest and apoptosis in human hepatoma cell HepG2. Initial extraction and identification were performed by HPLC, UPLC-TOF-MS/MS, and NMR analysis, respectively. Licochalcone B inhibited the HepG2 growth with IC50 (110.15 μ... | 10.1021/acs.jafc.9b00324 | 30,835,110 | D017209:Apoptosis; D053453:Caspase 9; D059447:Cell Cycle Checkpoints; D049109:Cell Proliferation; D047188:Chalcones; D029882:Glycyrrhiza uralensis; D056945:Hep G2 Cells; D006801:Humans; D008113:Liver Neoplasms; D008928:Mitochondria; D010936:Plant Extracts; D018517:Plant Roots | Journal of agricultural and food chemistry | 2,019 | D047188:Chalcones; D010936:Plant Extracts; C506433:CASP9 protein, human; D053453:Caspase 9; C541528:licochalcone B |
Tadalafil, a phosphodiesterase type 5 inhibitor, restores urethra and detrusor function in the initial phase of diabetes in rats. | OBJECTIVE
This study investigated the effects of tadalafil on the urethra and detrusor in the initial phase of diabetes in rats.
METHODS
Thirty-six female Sprague-Dawley rats were assigned to a non-diabetes (ND), diabetes (D), or tadalafil-treated diabetes (DT) group (n = 12 per group), with the DT group receiving or... | 10.1111/luts.12272 | 31,207,119 | D000818:Animals; D002217:Carbachol; D003921:Diabetes Mellitus, Experimental; D004558:Electric Stimulation; D005260:Female; D009119:Muscle Contraction; D009130:Muscle, Smooth; D058986:Phosphodiesterase 5 Inhibitors; D051381:Rats; D017207:Rats, Sprague-Dawley; D000068581:Tadalafil; D014521:Urethra; D001743:Urinary Bladde... | Lower urinary tract symptoms | 2,019 | D058986:Phosphodiesterase 5 Inhibitors; D000068581:Tadalafil; D002217:Carbachol |
Three-Dimensional Printing of Ceramics through "Carving" a Gel and "Filling in" the Precursor Polymer. | Achieving a viable process for three-dimensional (3D) printing of ceramics is a sought-after goal in a wide range of fields including electronics and sensors for harsh environments, microelectromechanical devices, energy storage materials, and structural materials, among others. Low laser absorption of ceramic powders ... | 10.1021/acsami.0c08260 | 32,551,471 | ACS applied materials & interfaces | 2,020 | ||
Identification of two distinct hereditary hemorrhagic telangiectasia patient subsets with different hepatic perfusion properties by combination of contrast-enhanced ultrasound (CEUS) with perfusion imaging quantification. | BACKGROUND
Hereditary hemorrhagic telangiectasia (HHT) is marked by arteriovenous fusion comprising hepatic vascular malformations (HVaMs) with the chance of bleeding.
AIMS
We investigated HVaMs in HHT patients by combination of contrast-enhanced ultrasound (CEUS) with perfusion imaging quantification to be able to s... | 10.1371/journal.pone.0215178 | 30,973,932 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D003199:Computer Systems; D003287:Contrast Media; D006801:Humans; D008099:Liver; D008102:Liver Circulation; D008297:Male; D045423:Microbubbles; D055806:Microvessels; D008875:Middle Aged; D055420:Perfusion Imaging; D012189:Retrospective Stud... | PloS one | 2,019 | D003287:Contrast Media |
Defective mycolic acid biosynthesis in a mutant of Mycobacterium smegmatis. | A mutant of Mycobacterium smegmatis defective in mycolic acid biosynthesis was isolated following chemical mutagenesis. Fatty acids were extracted from the mutant and subjected to structural analysis by thin-layer chromatography and high-performance liquid chromatography (HPLC) of both methyl and p-bromophenacyl ester ... | 10.1099/00221287-137-9-2197 | 1,748,873 | D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D009154:Mutation; D009161:Mycobacterium; D009171:Mycolic Acids | Journal of general microbiology | 1,991 | D009171:Mycolic Acids |
Smartteen- a computer assisted cognitive behavior therapy for Indian adolescents with depression- a pilot study. | The prevalence of unipolar depression among adolescents in India is high. Cognitive behavior therapies (CBTs) are considered the current gold standard treatment for depression in adolescents; however, their access is limited in India. Given the ubiquity of technology including smartphones and computers, technology can ... | 10.1016/j.ajp.2020.101970 | 32,114,331 | D000293:Adolescent; D015928:Cognitive Behavioral Therapy; D003863:Depression; D005260:Female; D006801:Humans; D008297:Male; D010865:Pilot Projects; D011569:Psychiatric Status Rating Scales; D016037:Single-Blind Method; D013813:Therapy, Computer-Assisted; D055815:Young Adult | Asian journal of psychiatry | 2,020 | |
Frostbite. | The diverse methods of therapy are directed at the mechanisms of freezing damage to tissues and the pathophysiology of the response. To prevent tissue loss, prompt rewarming of the frozen tissue is the most important treatment--practically all else is conservative wound care. Once rewarming is complete, little more can... | 6,171,379 | D003646:Debridement; D003911:Dextrans; D004487:Edema; D005627:Frostbite; D006493:Heparin; D006358:Hot Temperature; D006801:Humans; D012110:Reserpine; D013562:Sympathectomy; D014043:Tolazoline; D014665:Vasodilator Agents | Comprehensive therapy | 1,981 | D003911:Dextrans; D014665:Vasodilator Agents; D012110:Reserpine; D006493:Heparin; D014043:Tolazoline | |
Cultural identity, clothing and common mental disorder: a prospective school-based study of white British and Bangladeshi adolescents. | OBJECTIVE
Cultural integration is the healthiest outcome for young people living in multicultural societies. This paper investigates the influence of different cultural identities on the risk of common mental disorders among Bangladeshi and white British pupils.
DESIGN
The cultural identity of 11-14-year-old school p... | 10.1136/jech.2007.063149 | 18,413,457 | D000069:Acculturation; D000293:Adolescent; D044466:Asian People; D001459:Bangladesh; D003020:Clothing; D003469:Culture; D005260:Female; D033062:Friends; D006801:Humans; D008131:London; D008297:Male; D001523:Mental Disorders; D010379:Peer Group; D011446:Prospective Studies; D012307:Risk Factors; D012737:Sex Factors; D01... | Journal of epidemiology and community health | 2,008 | |
Biogenic amine content during the production and ripening of Sremski kulen, Serbian traditional dry fermented sausage. | Sremski kulen is a wide diameter dry fermented sausage, produced from pork, seasoned with red spicy paprika, stuffed into pork cecum, and preserved by smoking, fermentation and drying. Due to specific ripening process, Sremski kulen is suitable for the accumulation of biogenic amines. Therefore, the aminogenesis was st... | 10.1111/asj.13466 | 33,043,554 | D000818:Animals; D001679:Biogenic Amines; D002103:Cadaverine; D055598:Chemical Phenomena; D002851:Chromatography, High Pressure Liquid; D005285:Fermentation; D005504:Food Analysis; D005511:Food Handling; D005516:Food Microbiology; D005519:Food Preservation; D063427:Food Quality; D059022:Food Safety; D006863:Hydrogen-Io... | Animal science journal = Nihon chikusan Gakkaiho | 2,020 | D001679:Biogenic Amines; D002103:Cadaverine; D011700:Putrescine; D014439:Tyramine |
A protocol for Italian validation of DEMQoL-Proxy Scale: assessing the Quality of Life of people with moderate or mild dementia. | In this paper, we propose an adaptation of a protocol for a tool's validation. We have utilized this phases-theory to validate in Italian language an instrument to assess Quality of Life for people with moderate or mild dementia. We will explain the example of our Italian validation of DEMQoL-Proxy considering each De ... | 10.23750/abm.v92iS2.11974 | 34,328,128 | D003704:Dementia; D006801:Humans; D007558:Italy; D007802:Language; D011788:Quality of Life; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires | Acta bio-medica : Atenei Parmensis | 2,021 | |
Recognizing Atypical Dopa-Responsive Dystonia and Its Mimics. | PURPOSE OF REVIEW
Dopa-responsive dystonia (DRD) encompasses a group of phenotypically and genetically heterogeneous neurochemical disorders. Classic GTP cyclohydrolase 1 (GCH-1)-associated DRD consists of early-onset lower limb asymmetrical dystonia, with sleep benefit, diurnal variation, and excellent and sustained r... | 10.1212/CPJ.0000000000001125 | 34,992,971 | Neurology. Clinical practice | 2,021 | ||
Fermented Soymilk Alleviates Lipid Accumulation by Inhibition of SREBP-1 and Activation of NRF-2 in the Hepatocellular Steatosis Model. | Ingredients of soy and fermented soy products have been widely utilized as food supplements for health-enhancing properties. The aim of this study was to evaluate the effects of fermented soymilk (FSM) and soymilk (SM) on free fatty acid-induced lipogenesis in the hepatocellular steatosis model. HepG2 cells were incuba... | 10.4014/jmb.1707.07061 | 29,169,220 | D019149:Bioreactors; D006528:Carcinoma, Hepatocellular; D049109:Cell Proliferation; D004967:Estrogens; D005234:Fatty Liver; D005285:Fermentation; D019833:Genistein; D056945:Hep G2 Cells; D006801:Humans; D050356:Lipid Metabolism; D050155:Lipogenesis; D008113:Liver Neoplasms; D020935:MAP Kinase Signaling System; D051267:... | Journal of microbiology and biotechnology | 2,018 | D004967:Estrogens; D051267:NF-E2-Related Factor 2; D051780:Sterol Regulatory Element Binding Protein 1; D019308:Palmitic Acid; D019833:Genistein |
[Primary care physicians, internet and educational media. Preferences, usages and appraisal in a 6-year comparison]. | BACKGROUND AND PURPOSE
Several studies suggest that primary care physicians prefer "traditional" media like journals or quality circles for their postgraduate medical education. This survey was designed to gain a better understanding of primary care physicians' learning media preferences. The actual results were compar... | 10.1007/s00063-008-1055-6 | 18,548,212 | D000328:Adult; D001291:Attitude of Health Personnel; D002755:Choice Behavior; D003194:Computer-Assisted Instruction; D003625:Data Collection; D004502:Education, Medical, Continuing; D005194:Family Practice; D005260:Female; D005858:Germany; D006801:Humans; D007388:Internal Medicine; D020407:Internet; D008297:Male; D0088... | Medizinische Klinik (Munich, Germany : 1983) | 2,008 | |
Tobacco cessation support among dentists: A cross-sectional survey in Saudi Arabia and Kuwait. | INTRODUCTION
This study aims to explore the smoking prevalence among a sample of dentists working in two Gulf countries, and to assess the association between smoking habit and socio-professional factors affecting their attitude towards tobacco cessation activities, including barriers that prevent them from practicing ... | 10.18332/tpc/75795 | 32,432,195 | Tobacco prevention & cessation | 2,017 | ||
The GU-MACH study: the effect of 1-week omeprazole triple therapy on Helicobacter pylori infection in patients with gastric ulcer. | AIMS
To study the efficacy of omeprazole triple therapy in the eradication of Helicobacter pylori in patients with active gastric ulcer, and to assess healing and relapse of gastric ulcer.
METHODS
A double-blind, randomized study was carried out in 18 centres in Germany, Hungary and Poland. Patients (n = 160) with ga... | 10.1046/j.1365-2036.1999.00535.x | 10,383,498 | D000328:Adult; D000368:Aged; D000897:Anti-Ulcer Agents; D004311:Double-Blind Method; D005260:Female; D016481:Helicobacter Infections; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D009853:Omeprazole; D010349:Patient Compliance; D012008:Recurrence; D013276:Stomach Ulcer | Alimentary pharmacology & therapeutics | 1,999 | D000897:Anti-Ulcer Agents; D009853:Omeprazole |
GTP energy dependence of endocytosis and autophagy in the aging brain and Alzheimer's disease. | Increased interest in the aging and Alzheimer's disease (AD)-related impairments in autophagy in the brain raise important questions about regulation and treatment. Since many steps in endocytosis and autophagy depend on GTPases, new measures of cellular GTP levels are needed to evaluate energy regulation in aging and ... | 10.1007/s11357-022-00717-x | 36,622,562 | D006801:Humans; D000544:Alzheimer Disease; D001343:Autophagy; D004705:Endocytosis; D020691:rab GTP-Binding Proteins; D001921:Brain; D006160:Guanosine Triphosphate | GeroScience | 2,023 | D020691:rab GTP-Binding Proteins; D006160:Guanosine Triphosphate |
50 Hz magnetic field exposure alters onset of S-phase in normal human fibroblasts. | This study was undertaken to investigate whether power frequency magnetic fields can affect the kinetics of cell cycle progression in exposed human cells. To achieve this, cultures of normal human fibroblasts were synchronised in the G(0) phase of the cell cycle and exposed to 50 Hz magnetic fields at a range of flux d... | 10,495,310 | D002453:Cell Cycle; D002478:Cells, Cultured; D003584:Cytological Techniques; D004247:DNA; D005346:Fibroblast Growth Factors; D005347:Fibroblasts; D005609:Free Radicals; D016193:G1 Phase; D006801:Humans; D008280:Magnetics; D019275:Radiopharmaceuticals; D011994:Recombinant Proteins; D016192:Resting Phase, Cell Cycle; D01... | Bioelectromagnetics | 1,999 | D005609:Free Radicals; D019275:Radiopharmaceuticals; D011994:Recombinant Proteins; D014316:Tritium; D005346:Fibroblast Growth Factors; D004247:DNA; D013936:Thymidine | |
Notch one up to stroma: endothelial notch prevents inflammation and myeloproliferation. | In this issue of Cell Stem Cell, Wang et al. (2014) describe a signaling axis present in bone marrow stromal cells that suppresses inflammation and myeloid expansions. Loss of endothelial Notch signaling leads to deregulation of miR-155 expression, activation of NF-kB, and increased proinflammatory cytokine production,... | 24,996,160 | D000818:Animals; D001853:Bone Marrow; D019337:Hematologic Neoplasms; D006801:Humans; D035683:MicroRNAs; D009196:Myeloproliferative Disorders; D051880:Receptors, Notch | Cell stem cell | 2,014 | D035683:MicroRNAs; C532623:Mirn155 microRNA, mouse; D051880:Receptors, Notch | |
Cellulose Nanofibers Isolated from the Cuscuta Reflexa Plant as a Green Reinforcement of Natural Rubber. | In the present work, we used the steam explosion method for the isolation of cellulose nanofiber (CNF) from Cuscuta reflexa, a parasitic plant commonly seen in Kerala and we evaluated its reinforcing efficiency in natural rubber (NR). Fourier Transform Infrared Spectroscopy (FTIR), X-Ray Diffraction (XRD), Scanning Ele... | 10.3390/polym12040814 | 32,260,346 | Polymers | 2,020 | ||
Quantification of aromatic amines derived from azo colorants in textile by ion-pairing liquid chromatography tandem mass spectrometry. | Azo dyes can metabolize back to precursor aromatic amines (arylamines), which are potentially carcinogenic. The ISO 14362-1:2017 standard requires the determination of the arylamines, produced from textile samples, preferably by using the gas chromatography mass spectrometric (GC-MS) method. This paper presents an ion-... | 10.1016/j.jchromb.2019.121957 | 31,887,557 | D000588:Amines; D001391:Azo Compounds; D002851:Chromatography, High Pressure Liquid; D057230:Limit of Detection; D016014:Linear Models; D015203:Reproducibility of Results; D053719:Tandem Mass Spectrometry; D013784:Textiles | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences | 2,020 | D000588:Amines; D001391:Azo Compounds |
Personal projects: a useful approach to the study of occupation. | A comprehensive and useful understanding of human occupation requires research methods that capture its individual dimensions while permitting analyses within and across groups. In this article we describe the construct of personal projects and the research method of personal projects analysis. Both have their origins ... | 10.5014/ajot.52.6.439 | 9,612,494 | D006040:Goals; D006801:Humans; D008960:Models, Psychological; D009788:Occupational Therapy; D009790:Occupations; D010549:Personal Satisfaction; D012107:Research Design; D012649:Self Concept | The American journal of occupational therapy : official publication of the American Occupational Therapy Association | 1,998 | |
COVID-19 vaccine uptake and associated factors among pregnant women attending antenatal care in Debre Tabor public health institutions: A cross-sectional study. | Background
Vaccination is the best means of reducing the increased risk of severe COVID-19 during pregnancy. Data on COVID-19 vaccine uptake among pregnant women in Ethiopia is scarce. Thus, this study aimed to assess COVID-19 vaccine uptake and associated factors among pregnant women.
Method
An institution-based cro... | 10.3389/fpubh.2022.919494 | 35,928,488 | D000086382:COVID-19; D000086663:COVID-19 Vaccines; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D011247:Pregnancy; D037841:Pregnant Women; D011295:Prenatal Care; D011634:Public Health | Frontiers in public health | 2,022 | D000086663:COVID-19 Vaccines |
Latanoprost uptake and release from commercial contact lenses. | This study investigated the potential of delivering an anti-glaucoma drug using commercial silicone hydrogel (SiHy) contact lenses. The moderately hydrophobic drug latanoprost was rapidly loaded in 4 min by swelling contact lenses in a solution of the drug in n-propanol. A fraction of the drug was radiolabeled, thus al... | 10.1080/09205063.2019.1669126 | 31,526,302 | D003263:Contact Lenses, Hydrophilic; D065546:Drug Liberation; D007700:Kinetics; D000077338:Latanoprost; D012997:Solvents | Journal of biomaterials science. Polymer edition | 2,020 | D012997:Solvents; D000077338:Latanoprost |
Protective effect of Amomi semen extract on alloxan-induced pancreatic beta-cell damage. | The protective effect of Amomi semen extract (ASE) on alloxan-induced pancreatic beta-cell damage was investigated in HIT T-15 cells, a Syrian hamster pancreatic beta-cell line. Alloxan caused pancreatic beta-cell damage through the generation of reactive oxygen species (ROS), the elevation of cytosolic free Ca2+, DNA ... | 10.1002/ptr.2271 | 17,724,760 | D000255:Adenosine Triphosphate; D000496:Alloxan; D035801:Amomum; D000818:Animals; D002118:Calcium; D002460:Cell Line; D002470:Cell Survival; D053938:DNA Fragmentation; D050417:Insulin-Secreting Cells; D009243:NAD; D010936:Plant Extracts; D017382:Reactive Oxygen Species; D013997:Time Factors | Phytotherapy research : PTR | 2,008 | D010936:Plant Extracts; D017382:Reactive Oxygen Species; D009243:NAD; D000496:Alloxan; D000255:Adenosine Triphosphate; D002118:Calcium |
Concentration, fractionation, and ecological risk assessment of heavy metals and phosphorus in surface sediments from lakes in N. Greece. | The presence of phosphorus (P) and heavy metals (HMs) in surface sediments originating from lakes Volvi, Kerkini, and Doirani (N. Greece), as well as their fractionation patterns, were investigated. No statistically significant differences in total P content were observed among the studied lakes, but notable difference... | 10.1007/s10653-019-00509-x | 31,933,038 | D005591:Chemical Fractionation; D004784:Environmental Monitoring; D019015:Geologic Sediments; D006115:Greece; D060106:Lakes; D019216:Metals, Heavy; D010758:Phosphorus; D018570:Risk Assessment; D012621:Seasons; D014874:Water Pollutants, Chemical | Environmental geochemistry and health | 2,020 | D019216:Metals, Heavy; D014874:Water Pollutants, Chemical; D010758:Phosphorus |
Formation of the exceptional [M - H]+ cation in atmospheric pressure ionization mass spectrometry analysis of 2-(diphenylsilyl) cyclopropanecarboxylate esters. | RATIONALE
In general, ionization of analytes in atmospheric pressure ionization mass spectrometry (API-MS) in positive ion mode results in the formation of protonated molecules ([M + H]+ ) and/or cationized molecules (e.g., [M + Na]+ ). The formation of specific [M - H]+ cations in the API process is of significant int... | 10.1002/rcm.8866 | 32,559,337 | Rapid communications in mass spectrometry : RCM | 2,020 | ||
Peripheral Inflammatory Blood Markers in Diagnosis of Glioma and IDH Status. | Objective Gliomas are the most common intracranial tumors. Histopathology and neuroimaging are the main modalities used for diagnosis and treatment response monitoring. However, both are expensive and insensitive methods and can cause neurological deterioration. This study aimed to develop a minimally invasive periphe... | 10.1055/s-0040-1721166 | 33,551,616 | Journal of neurosciences in rural practice | 2,021 | ||
Needs for tooth replacement. | The prime objective of dental care is maintaining a natural functional dentition for life. It is expected that a growing group of adults will keep their dentition into old age. Although routine prosthodontic care will still be important in the future the treatment strategy for older adults and elderly people with a red... | 8,478,127 | D017266:Dental Prosthesis; D003793:Dental Restoration, Permanent; D006801:Humans; D010347:Patient Care Planning; D016388:Tooth Loss | International dental journal | 1,993 | ||
[First trials of inhalation-therapy in Poland]. | The gas-therapy unit was founded by professor Oszacki in Cracow's St. Lazarus Hospital in 1937. This was the beginning of the new therapy, well known in West Europe. Well equipped and modern provided unit worked nearly two years. In 1939 the oxygen explosion and subsequent fire completely destroyed it. In this accident... | 10,575,929 | D049673:History, 20th Century; D010102:Oxygen Inhalation Therapy; D011044:Poland; D012138:Respiratory Therapy; D012140:Respiratory Tract Diseases | Przeglad lekarski | 1,999 | ||
Endoscopic partial plantar fasciotomy as a treatment alternative in plantar fasciitis. | PURPOSE OF THE STUDY
One of the most common causes of chronic heel pain is plantar fasciitis (ocalcaneal spur?). This condition most frequently occurs in patients over the age of 40. In most cases pain can be reduced or ceased by conservativ treatment, but in some patients therapy-resistant chronic pain can also develo... | 18,198,092 | D000328:Adult; D004724:Endoscopy; D036981:Fasciitis, Plantar; D000071938:Fasciotomy; D005260:Female; D005528:Foot; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement | Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca | 2,007 | ||
Genetic architecture of terpene chemistry and growth traits and the impact of inbreeding on these traits in western redcedar (Thuja plicata). | Western redcedar (WRC; Thuja plicata) is a conifer of the Pacific Northwest of North America prized for its durable and rot-resistant wood. WRC has naturally low outcrossing rates and readily self-fertilizes in nature. Challenges faced in WRC breeding and propagation involve selecting trees for accelerated growth while... | 10.1111/eva.13526 | 36,969,136 | Evolutionary applications | 2,023 | ||
Hydrogen and deuterium in myoglobin as seen by a neutron structure determination at 1.5 A resolution. | From the first days of protein neutron structure determination sperm whale myoglobin was an object under investigation [Nature 224 (1969) 143, J. Mol. Biol. 220 (1991) 381]. Nevertheless myoglobin is still of interest [Proc. Natl. Acad. Sci. USA 97 (2000) 3872]. The feasibility of the monochromatic neutron diffractomet... | 10.1016/s0301-4622(01)00255-1 | 12,062,378 | D000818:Animals; D003461:Crystallography; D003903:Deuterium; D006859:Hydrogen; D008786:Metmyoglobin; D009068:Movement; D009211:Myoglobin; D009502:Neutrons; D018583:Pliability; D011487:Protein Conformation; D012542:Scattering, Radiation; D012680:Sensitivity and Specificity; D014867:Water; D014907:Whales | Biophysical chemistry | 2,002 | D009211:Myoglobin; D014867:Water; D008786:Metmyoglobin; D006859:Hydrogen; D003903:Deuterium |
Patent foramen ovale and stroke in childhood: A systematic review of the literature. | BACKGROUND
Stroke in association with a patent foramen ovale (PFO) may be due to paradoxical embolization via a right to left intracardiac shunt but the exact contribution of PFO to stroke or stroke recurrence in childhood remains unclear.
METHODS
To review the relationship of a PFO with stroke, and evaluate associat... | 27,169,856 | D015897:Comorbidity; D019320:Embolism, Paradoxical; D054092:Foramen Ovale, Patent; D006801:Humans; D012307:Risk Factors; D020521:Stroke | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society | 2,016 | ||
Dapagliflozin Enhances Fat Oxidation and Ketone Production in Patients With Type 2 Diabetes. | OBJECTIVE
Insulin resistance is associated with mitochondrial dysfunction and decreased ATP synthesis. Treatment of individuals with type 2 diabetes mellitus (T2DM) with sodium-glucose transporter 2 inhibitors (SGLT2i) improves insulin sensitivity. However, recent reports have demonstrated development of ketoacidosis i... | 10.2337/dc15-2688 | 27,561,923 | D000293:Adolescent; D000328:Adult; D000368:Aged; D001559:Benzhydryl Compounds; D001786:Blood Glucose; D002153:Calorimetry, Indirect; D003404:Creatinine; D003924:Diabetes Mellitus, Type 2; D004311:Double-Blind Method; D004791:Enzyme Inhibitors; D005934:Glucagon; D005960:Glucosides; D006801:Humans; D007328:Insulin; D0073... | Diabetes care | 2,016 | D001559:Benzhydryl Compounds; D001786:Blood Glucose; D004791:Enzyme Inhibitors; D005960:Glucosides; D007328:Insulin; D007659:Ketones; D051297:Sodium-Glucose Transporter 2; D000077203:Sodium-Glucose Transporter 2 Inhibitors; C529054:dapagliflozin; D005934:Glucagon; D003404:Creatinine |
Galanin counteracts the inhibitory effects of glucocorticoids on growth hormone secretion in the rat. | The aim of our study was to investigate the effect of galanin on baseline and growth hormone (GH)-releasing hormone (GHRH)-stimulated GH concentrations in conscious, freely moving rats receiving long-term glucocorticoid treatment. Animals were treated for 7 days with an intraperitoneal injection of either vehicle or de... | 10.1016/0026-0495(95)90269-4 | 7,532,779 | D000818:Animals; D003907:Dexamethasone; D004347:Drug Interactions; D019004:Galanin; D013006:Growth Hormone; D013007:Growth Hormone-Releasing Hormone; D008297:Male; D010455:Peptides; D051381:Rats; D017207:Rats, Sprague-Dawley | Metabolism: clinical and experimental | 1,995 | D010455:Peptides; D003907:Dexamethasone; D019004:Galanin; D013006:Growth Hormone; D013007:Growth Hormone-Releasing Hormone |
Phase Equilibria in binary mixtures of dimyristoylphosphatidylcholine and cardiolipin. | Paramagnetic resonance spectra of the spin-label 2,2,6,6-tetramethylpiperidinyl-l-oxy have been used to study phase separations in binary mixtures of dimyristoyl-phosphatidylcholine and cardiolipin. Two different samples of cardiolipin were used: (i) One sample contained calcium ions at a mole ratio of calcium:cardioli... | 10.1021/bi00526a018 | 6,272,842 | D002118:Calcium; D002308:Cardiolipins; D003497:Cyclic N-Oxides; D004134:Dimyristoylphosphatidylcholine; D004578:Electron Spin Resonance Spectroscopy; D007700:Kinetics; D008081:Liposomes; D008433:Mathematics; D010713:Phosphatidylcholines; D013050:Spectrometry, Fluorescence; D013113:Spin Labels | Biochemistry | 1,981 | D002308:Cardiolipins; D003497:Cyclic N-Oxides; D008081:Liposomes; D010713:Phosphatidylcholines; D013113:Spin Labels; D002118:Calcium; C001803:tempol; D004134:Dimyristoylphosphatidylcholine |
Determination of two sites of automethylation in bovine erythrocyte protein (D-aspartyl/L-isoaspartyl) carboxyl methyltransferase. | Protein (D-aspartyl/L-isoaspartyl) carboxyl methyltransferase (PCM, E.C. 2.1.1.77) was previously shown to be enzymatically methyl esterified in an autocatalytic manner at altered aspartyl residues; methyl esters are observed in a subpopulation of the enzyme termed the alpha PCM fraction [Lindquist and McFadden (1994),... | 10.1007/BF01886817 | 8,838,596 | D000595:Amino Acid Sequence; D000818:Animals; D001216:Asparagine; D001224:Aspartic Acid; D001665:Binding Sites; D002417:Cattle; D002851:Chromatography, High Pressure Liquid; D003488:Cyanogen Bromide; D004912:Erythrocytes; D008745:Methylation; D008969:Molecular Sequence Data; D010449:Peptide Mapping; D010455:Peptides; D... | Journal of protein chemistry | 1,996 | D010455:Peptides; D001224:Aspartic Acid; D001216:Asparagine; D011497:Protein O-Methyltransferase; D014357:Trypsin; D003488:Cyanogen Bromide |
The relationship between sIgM positive lymph-node lymphocytes and breast cancer metastasis. | The relative frequency of lymphocytes with surface immunoglobulins (sIgM, sIgG, sIgA) was studied in breast-cancer patients' axillary lymph nodes by the immunofluorescence technique. The study encompassed a total of 105 patients, most of whom had infiltrating ductal carcinoma (IDC). The results have indicated a signifi... | 10.1002/jso.2930110114 | 219,301 | D001365:Axilla; D001943:Breast Neoplasms; D002285:Carcinoma, Intraductal, Noninfiltrating; D005260:Female; D006801:Humans; D007075:Immunoglobulin M; D008198:Lymph Nodes; D008207:Lymphatic Metastasis; D008214:Lymphocytes; D011379:Prognosis; D011947:Receptors, Antigen, B-Cell | Journal of surgical oncology | 1,979 | D007075:Immunoglobulin M; D011947:Receptors, Antigen, B-Cell |
Measurement of the percentage volume particle size distribution of powdered microcrystalline cellulose using reflectance near-infrared spectroscopy. | This is the first reported method for determining the percentage volume particle size distribution of a powder (microcrystalline cellulose) by near-infrared (NIR) reflectance spectroscopy. A total of 113 samples of powdered microcrystalline cellulose were used from six different commercially available grades, with diff... | 10.1039/b307263k | 14,700,224 | D002482:Cellulose; D003460:Crystallization; D010316:Particle Size; D019265:Spectroscopy, Near-Infrared | The Analyst | 2,003 | D002482:Cellulose |
Studies on the intracellular distribution of Sindbis messenger RNA in infected chick-embryo fibroblasts. 1. Presence of extrapolyribosomal 26-S RNA in the membrane fraction. | Four hours after infection with Sindbis virus, chick embryo fibroblasts were studied by electron microscopy and cell fractionation. Electron microscopy of infected and non-infected cells revealed that infection produced a disaggregation of polyribosomes into monomers. Apart from this observation most cells appeared wel... | 10.1111/j.1432-1033.1980.tb04288.x | 7,358,048 | D000818:Animals; D002499:Centrifugation, Density Gradient; D002642:Chick Embryo; D005347:Fibroblasts; D007425:Intracellular Membranes; D008099:Liver; D008854:Microscopy, Electron; D009154:Mutation; D009994:Osmolar Concentration; D011132:Polyribosomes; D011691:Puromycin; D012333:RNA, Messenger; D012335:RNA, Ribosomal; D... | European journal of biochemistry | 1,980 | D012333:RNA, Messenger; D012335:RNA, Ribosomal; D012367:RNA, Viral; D011691:Puromycin |
Inherited burden of disease: agricultural dams and the persistence of bloody urine (Schistosomiasis hematobium) in the Upper East Region of Ghana, 1959-1997. | A major agricultural development project was commissioned to celebrate Ghana's independence in 1957. In the Upper Region along the border with Upper Volta now named Burkina Faso, a total of 185 clay-core dams were constructed in 15 years to enhance village water supplies during the 6-month dry season. In a concentrated... | 10.1016/s0277-9536(02)00021-7 | 12,473,309 | D000293:Adolescent; D000383:Agriculture; D000818:Animals; D002648:Child; D017281:Cost of Illness; D019353:Endemic Diseases; D005869:Ghana; D006417:Hematuria; D006801:Humans; D015995:Prevalence; D012548:Schistosoma haematobium; D012553:Schistosomiasis haematobia; D014867:Water; D014881:Water Supply | Social science & medicine (1982) | 2,003 | D014867:Water |
Experimental and clinical effects of magnesium infusion in the treatment of neonatal pulmonary hypertension. | The appropriate treatment of persistent pulmonary hypertension of the newborn has led to the search for a specific pulmonary vasodilator. Persistent pulmonary hypertension of the newborn is characterized by a high pulmonary vascular resistance resulting in right to left shunting across the fetal channels. The ratio of ... | 8,861,137 | D000818:Animals; D001777:Blood Coagulation; D002121:Calcium Channel Blockers; D000242:Cyclic AMP; D006152:Cyclic GMP; D004195:Disease Models, Animal; D006801:Humans; D006976:Hypertension, Pulmonary; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D008168:Lung; D008278:Magnesium Sulfate; D008471:Meconium Asp... | Magnesium research | 1,995 | D002121:Calcium Channel Blockers; D014665:Vasodilator Agents; D008278:Magnesium Sulfate; D000242:Cyclic AMP; D019001:Nitric Oxide Synthase; D013930:Thromboxane-A Synthase; D006152:Cyclic GMP; D009543:Nifedipine | |
Abnormal endogenous carbon monoxide production in children with ineffective erythropoiesis. | The aim of this study was to evaluate the extent of endogenous carbon monoxide production in subjects with ineffective erythropoiesis. Carboxyhaemoglobin concentrations were measured in eight transfused and eight nontransfused thalassemic patients. Measurements were made on venous blood collected under controlled condi... | 10.1177/000456329202900404 | 1,642,444 | D000293:Adolescent; D001803:Blood Transfusion; D002248:Carbon Monoxide; D002263:Carboxyhemoglobin; D002648:Child; D002675:Child, Preschool; D004920:Erythropoiesis; D005260:Female; D006801:Humans; D008297:Male; D013789:Thalassemia | Annals of clinical biochemistry | 1,992 | D002248:Carbon Monoxide; D002263:Carboxyhemoglobin |
[The astrocyte glia of the brain in herpetic encephalitis in children]. | Astrocytic changes were followed up in the brain of infants who had died of herpetic encephalitis. Neuro-morphological examinations revealed astrocytic structural changes directed to reinforcement of the blood-brain barrier, localization of the infection and, possibly, to inactivation of the virus. | 7,524,252 | D001253:Astrocytes; D001921:Brain; D018792:Encephalitis, Viral; D017809:Fatal Outcome; D005260:Female; D006561:Herpes Simplex; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009336:Necrosis; D013194:Staining and Labeling | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova | 1,994 | ||
Parotid gland as an initial site of metastasis. | The parotid gland is an uncommon site of metastasis from carcinomas arising outside the head and neck region. Involvement of the parotid gland as an initial site of metastasis or presentation is rare. The present case report is the first, to our knowledge, to describe the management and outcome of an elderly man whose ... | 10.1111/j.1440-1673.2004.01253.x | 15,027,931 | D000368:Aged; D002294:Carcinoma, Squamous Cell; D006801:Humans; D008175:Lung Neoplasms; D008207:Lymphatic Metastasis; D008297:Male; D010307:Parotid Neoplasms; D014057:Tomography, X-Ray Computed | Australasian radiology | 2,004 | |
CDK/GSK-3 inhibitors as a new approach for the treatment of proliferative renal diseases. | Proliferation of specific renal cell types leads to the development of many types of kidney disease. Given the central role that both cyclin-dependent kinases (CDKs) and glycogen synthase kinase-3 (GSK-3) play in promoting aberrant proliferation within the kidney, these paralogous serine/threonine kinases are being exp... | 10.1358/dnp.2006.19.6.985939 | 16,971,968 | D000818:Animals; D000893:Anti-Inflammatory Agents; D015415:Biomarkers; D049109:Cell Proliferation; D018844:Cyclin-Dependent Kinases; D038362:Glycogen Synthase Kinase 3; D006801:Humans; D007674:Kidney Diseases; D047428:Protein Kinase Inhibitors | Drug news & perspectives | 2,006 | D000893:Anti-Inflammatory Agents; D015415:Biomarkers; D047428:Protein Kinase Inhibitors; D018844:Cyclin-Dependent Kinases; D038362:Glycogen Synthase Kinase 3 |
Vancomycin-resistant enterococcus in end-stage renal disease. | The percentage of nosocomial vancomycin-resistant enterococci (VRE) has been increasing rapidly in the United States. This has recently resulted in recommendations to reserve vancomycin use for cases with proven resistance to other antimicrobials. We prospectively investigated the incidence of VRE in our dialysis popul... | 10.1053/ajkd.1998.v32.pm9740157 | 9,740,157 | D000900:Anti-Bacterial Agents; D003428:Cross Infection; D018432:Drug Resistance, Multiple; D016983:Enterococcus; D016908:Gram-Positive Bacterial Infections; D006801:Humans; D007676:Kidney Failure, Chronic; D008657:Metabolic Clearance Rate; D008826:Microbial Sensitivity Tests; D010530:Peritoneal Dialysis; D011446:Prospe... | American journal of kidney diseases : the official journal of the National Kidney Foundation | 1,998 | D000900:Anti-Bacterial Agents; D014640:Vancomycin |
Reticuloendothelial system phagocytic function in obstructive jaundice and its modification by a muramyl dipeptide analogue. | Measurement of reticulo-endothelial system (RES) phagocytic function by clearance of intravenous micro-aggregated human albumin (HMAA) showed prolonged clearance in both patients (p less than 0.001) and rats (p less than 0.001) with extrahepatic biliary tract obstruction compared with non-jaundiced controls. After the ... | 10.1159/000128676 | 3,792,414 | D000119:Acetylmuramyl-Alanyl-Isoglutamine; D000368:Aged; D000418:Albumins; D000818:Animals; D002779:Cholestasis; D006801:Humans; D008657:Metabolic Clearance Rate; D012157:Mononuclear Phagocyte System; D010587:Phagocytosis; D051381:Rats; D014018:Tissue Distribution | European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes | 1,987 | D000418:Albumins; D000119:Acetylmuramyl-Alanyl-Isoglutamine |
In vivo evaluation of the trabecular bone behavior to porous electrostatic spray deposition-derived calcium phosphate coatings. | OBJECTIVES
Electrostatic spray deposition (ESD) is a new technique to deposit calcium phosphate (CaP) coatings. The aim of the present study was to evaluate the bone behavior of ESD CaP-coated implants with various degrees of crystallinities in the trabecular bone of the femoral condyle of goats.
MATERIAL AND METHODS... | 10.1111/j.1600-0501.2006.01314.x | 17,298,493 | D000818:Animals; D001031:Apatites; D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; D003460:Crystallization; D015921:Dental Implants; D005260:Female; D005270:Femur Head; D006041:Goats; D006358:Hot Temperature; D055672:Static Electricity; D013499:Surface Properties; D014025:Titanium | Clinical oral implants research | 2,007 | D001031:Apatites; D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; D015921:Dental Implants; C020243:calcium phosphate; D014025:Titanium |
The ability of onion extract gel to improve the cosmetic appearance of postsurgical scars. | Superior wound healing with excellent cosmesis is critical in superficial dermal wounds created when cosmetically unacceptable lesions are removed from the body. Dermatologists frequently remove seborrheic keratoses, nevi, and angiomas from the body with a superficial shave excision. The excision is designed to minimiz... | 10.1111/j.1473-2165.2008.00371.x | 18,482,012 | D000287:Administration, Topical; D000328:Adult; D002921:Cicatrix; D005260:Female; D005782:Gels; D006801:Humans; D017492:Keratosis, Seborrheic; D008297:Male; D013511:Minor Surgical Procedures; D019697:Onions; D008517:Phytotherapy; D010936:Plant Extracts; D016037:Single-Blind Method; D012867:Skin | Journal of cosmetic dermatology | 2,008 | D005782:Gels; D010936:Plant Extracts |
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