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Subtractive screening with the Mycobacterium tuberculosis surface protein phage display library.
Surface proteins consist of secreted and membrane proteins and play a central role in the interaction of the pathogen with its environment, especially in the pathogenicity of Mycobacterium tuberculosis (MTB). Research on surface proteins in MTB has focused on 2D electrophoresis of culture filtrate proteins (CFP), extra...
10.1016/j.tube.2011.07.007
21,900,047
D000465:Algorithms; D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D009169:Mycobacterium tuberculosis; D019151:Peptide Library
Tuberculosis (Edinburgh, Scotland)
2,011
D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D019151:Peptide Library
A novel multiplex poliovirus binding inhibition assay applicable for large serosurveillance and vaccine studies, without the use of live poliovirus.
Large-scale serosurveillance or vaccine studies for poliovirus using the "gold standard" WHO neutralisation test (NT) are very laborious and time consuming. With the polio eradication at hand and with the removal of live attenuated Sabin strains from the oral poliovirus vaccine (OPV), starting with type 2 (as of April ...
10.1016/j.jviromet.2016.12.006
27,988,324
D000914:Antibodies, Viral; D006801:Humans; D007118:Immunoassay; D007157:Immunologic Surveillance; D009500:Neutralization Tests; D017955:Poliovirus; D011054:Poliovirus Vaccine, Inactivated; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D038301:Virus Inactivation
Journal of virological methods
2,017
D000914:Antibodies, Viral; D011054:Poliovirus Vaccine, Inactivated
Physicochemical, digestibility and structural characteristics of starch isolated from banana cultivars.
Banana starches from diverse varieties (Macho, Morado, Valery and Enano Gigante) were studied in their physicochemical, structural and digestibility features. X-ray diffraction indicated that the banana starches present a B-type crystallinity pattern, with slight difference in the crystallinity level. Macho and Enano G...
25,839,789
D008970:Molecular Weight; D028521:Musa; D012995:Solubility; D013213:Starch; D014961:X-Ray Diffraction
Carbohydrate polymers
2,015
D013213:Starch
Cardiac considerations in liver transplantation.
Cardiovascular events have a major impact on overall outcomes after liver transplantation. Today's transplant patients are older than those in the past and therefore are more likely to have coexisting cardiac comorbidities. In addition, pathophysiologic effects of advanced liver disease on the circulatory system pose c...
10.3949/ccjm.89a.21006
34,983,801
D006321:Heart; D006801:Humans; D008107:Liver Diseases; D016031:Liver Transplantation; D011183:Postoperative Complications; D011184:Postoperative Period
Cleveland Clinic journal of medicine
2,022
[Aflatoxins and fungal community distribution during harvesting and processing of Platycladi Semen].
This study aimed to analyze aflatoxins content and fungal community distribution in the harvesting and processing of Platycladi Semen, and explore the key link that affects aflatoxins contamination. The related Platycladi Semen samples of different maturity periods(cone non-rupture period, early rupture, and complete r...
10.19540/j.cnki.cjcmm.20211025.102
35,178,980
D000348:Aflatoxins; D001231:Aspergillus flavus; D005506:Food Contamination; D000072761:Mycobiome; D012661:Semen; D053719:Tandem Mass Spectrometry
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
2,022
D000348:Aflatoxins
[Sports and activities after achilles tendon injury of the recreational athlete].
BACKGROUND There is abundant literature on the treatment of Achilles tendon rupture; however data on sports and recreational activities after this injury is scarce. PATIENTS AND METHODS 71 patients were assessed in a prospective cross-sectional study after an average of 3 years after Achilles tendon rupture. 44 patie...
10.1055/s-0028-1109825
20,108,185
D000125:Achilles Tendon; D000203:Activities of Daily Living; D000328:Adult; D001265:Athletic Injuries; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D011183:Postoperative Complications; D020127:Recovery of Function; D011998:Recreation; D01242...
Sportverletzung Sportschaden : Organ der Gesellschaft fur Orthopadisch-Traumatologische Sportmedizin
2,009
Effect of periostin on bone metabolic and autophagy factors during tooth eruption in mice.
This study aimed to investigate the effect of periostin (PN) on the expression of receptor activator of nuclear factor-κB ligand (RANKL), osteoprotegerin (OPG), microtubule-associated protein1 light chain 3B (LC3B), and Beclin1 in mouse alveolar bone specimens and cultured osteoblasts in vitro, to preliminarily explore...
10.1515/biol-2022-0663
37,589,010
Open life sciences
2,023
Normalization of atropine-induced postprandial dysrhythmias with gastric pacing.
Gastric pacing has received increasing attention recently. However, few studies have systematically assessed the effect of pacing on gastric dysrhythmias. The aims of this study were to investigate the effect of gastric pacing on gastric dysrhythmia and to explore whether the effect of gastric pacing was mediated via c...
10.1152/ajpgi.1999.276.2.G387
9,950,812
D000818:Animals; D001285:Atropine; D004285:Dogs; D004558:Electric Stimulation; D005260:Female; D005769:Gastrointestinal Motility; D018727:Muscarinic Antagonists; D016065:Myoelectric Complex, Migrating; D010507:Periodicity; D012016:Reference Values; D013270:Stomach
The American journal of physiology
1,999
D018727:Muscarinic Antagonists; D001285:Atropine
Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways.
Because mouse models play a crucial role in biomedical research related to the human nervous system, understanding the similarities and differences between mouse and human brain is of fundamental importance. Studies comparing transcription in human and mouse have come to varied conclusions, in part because of their rel...
10.1073/pnas.0914257107
20,616,000
D000544:Alzheimer Disease; D000818:Animals; D001921:Brain; D020869:Gene Expression Profiling; D053263:Gene Regulatory Networks; D006801:Humans; D008297:Male; D051379:Mice; D053764:Presenilin-1; D049490:Systems Biology
Proceedings of the National Academy of Sciences of the United States of America
2,010
D053764:Presenilin-1
Community-based parenteral anti-infective therapy (CoPAT). Pharmacokinetic and monitoring issues.
Community-based parenteral anti-infective therapy (CoPAT) has, over the past 20 years, increased rapidly in many parts of the world including North America, Europe, South America and Australia. CoPAT is a multidisciplinary activity demanding close cooperation between nurses, pharmacists and physicians, as well as with ...
10.2165/00003088-199835010-00005
9,673,835
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D004355:Drug Stability; D005260:Female; D018718:Home Infusion Therapy; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D017334:Teicoplanin; D014640:Vancomycin
Clinical pharmacokinetics
1,998
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D017334:Teicoplanin; D014640:Vancomycin
Patent ductus venosus does not lead to alimentary galactosaemia in preterm infants.
UNLABELLED The aim of this study was to investigate if an open ductus venosus representing a portal-caval shunt can lead to transient "alimentary galactosaemia" in preterm infants fed human breast milk. Twenty-six preterm infants (28-34 wk of gestational age) with open ductus venosus were included. Capillary blood samp...
10.1080/080352501300049424
11,236,050
D001724:Birth Weight; D001783:Blood Flow Velocity; D001786:Blood Glucose; D005693:Galactosemias; D005865:Gestational Age; D006503:Hepatic Veins; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D011168:Portal System; D011169:Portal Vein; D011170:Portasystemic Shunt, Surgical; D014471:Umbilical Veins
Acta paediatrica (Oslo, Norway : 1992)
2,001
D001786:Blood Glucose
(S)-N-{3-[1-cyclopropyl-1-(2,4-difluoro-phenyl)-ethyl]-1H-indol-7-yl}-methanesulfonamide: a potent, nonsteroidal, functional antagonist of the mineralocorticoid receptor.
A novel, potent series of indole analogs were recently developed as MR antagonists, culminating in 14. This compound represents the first MR antagonist in this class of molecules, exhibiting picomolar binding affinity and in vivo blood pressure lowering at pharmaceutically relevant doses.
10.1021/jm701186z
18,038,968
D000818:Animals; D000959:Antihypertensive Agents; D018360:Crystallography, X-Ray; D007211:Indoles; D000451:Mineralocorticoid Receptor Antagonists; D008958:Models, Molecular; D051381:Rats; D017207:Rats, Sprague-Dawley; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013449:Sulfonamides
Journal of medicinal chemistry
2,007
D000959:Antihypertensive Agents; D007211:Indoles; D000451:Mineralocorticoid Receptor Antagonists; C527716:N-(3-(1-cyclopropyl-1-(2,4-difluorophenyl)ethyl)-1H-indol-7-yl)methanesulfonamide; D013449:Sulfonamides
Diagnosis and treatment of hypoactive sexual desire disorder.
Hypoactive sexual desire disorder is a loss of thoughts and fantasies about sexual matters. Commonly encountered by gynecologists, this is a complaint frequently heard from older women. Causes, diagnosis, and treatment are presented.
10.1097/GRF.0b013e3181bf48c9
20,393,418
D000279:Administration, Cutaneous; D000284:Administration, Oral; D000375:Aging; D000728:Androgens; D004343:Drug Implants; D004335:Drug and Narcotic Control; D005260:Female; D005782:Gels; D006801:Humans; D007273:Injections, Intramuscular; D020018:Sexual Dysfunctions, Psychological; D013739:Testosterone
Clinical obstetrics and gynecology
2,009
D000728:Androgens; D004343:Drug Implants; D005782:Gels; D013739:Testosterone
Inhibition of growth factor effects in retinal pigment epithelial cells.
Several agents were examined for their effect on growth factor-stimulated processes in retinal pigment epithelial (RPE) cells. DNA synthesis was assessed by 3H-thymidine incorporation in density-arrested cells using previously determined maximally effective concentrations of various growth factors with and without test...
2,032,799
D000328:Adult; D002460:Cell Line; D002465:Cell Movement; D002633:Chemotaxis; D004247:DNA; D006131:Growth Inhibitors; D006801:Humans; D010857:Pigment Epithelium of Eye
Investigative ophthalmology & visual science
1,991
D006131:Growth Inhibitors; D004247:DNA
Intrinsic projections within visual cortex: evidence for orientation-specific local connections.
The functional organization of intrinsic connections within area 18 of cat visual cortex was studied using combined electrophysiological and anatomical techniques. Physiological recordings were first used to map the distribution of orientation preference, ocular dominance, and receptive-field location relative to the c...
10.1073/pnas.82.3.935
3,856,241
D000818:Animals; D002415:Cats; D004292:Dominance, Cerebral; D004594:Electrophysiology; D014793:Visual Cortex
Proceedings of the National Academy of Sciences of the United States of America
1,985
Diagnosis of recanalization of the intracranial artery has poor inter-rater reliability.
BACKGROUND AND PURPOSE Recanalization is the important outcome measure for acute stroke therapy. Several methods of recanalization assessment are used in clinical practice, but few studies have addressed their reliability. We, therefore, sought to assess interobserver reliability of the diagnosis of intracranial artery...
10.3174/ajnr.A2896
22,241,381
D000368:Aged; D002545:Brain Ischemia; D002533:Cerebral Angiography; D002548:Cerebral Revascularization; D005260:Female; D006801:Humans; D008297:Male; D015588:Observer Variation; D011379:Prognosis; D011856:Radiographic Image Enhancement; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitiv...
AJNR. American journal of neuroradiology
2,012
Baseline Substance Use Interferes with Maintenance of HIV Medication Adherence Skills.
Cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV improves both adherence and depression outcomes relative to enhanced treatment as usual (ETAU). However, in persons with injection drug use (PWIDU) histories, adherence gains seen during treatment have not been maintained postintervention. Theref...
10.1089/apc.2015.0340
27,158,849
D000328:Adult; D044966:Anti-Retroviral Agents; D019970:Cocaine-Related Disorders; D015928:Cognitive Behavioral Therapy; D003863:Depression; D005260:Female; D015658:HIV Infections; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D009293:Opioid-Related Disorders; D015819:Substance Abuse, ...
AIDS patient care and STDs
2,016
D044966:Anti-Retroviral Agents
Prediction of methicillin-resistant Staphylococcus aureus in patients with non-nosocomial pneumonia.
BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) is recognized as an important cause of not only hospital acquired pneumonia, but also non-nosocomial pneumonia. However, the risk factors for non-nosocomial MRSA pneumonia are not clearly defined. Our objective was to identify risk factors at admission that ...
10.1186/1471-2334-13-370
23,937,553
D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D017714:Community-Acquired Infections; D003428:Cross Infection; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus; D008875:Middle Aged; D018410:Pneumonia, Bacterial; D011023...
BMC infectious diseases
2,013
β-Functionalized trans-A2B2 push-pull tetrabenzoporphyrins.
A series of β-functionalized trans-A2B2 tetrabenzoporphyrins have been successfully designed and synthesized through newly developed regioselective bromination chemistry of porphyrins and a Pd(0) catalyzed three-step-one pot reaction. These benzoporphyrins exhibit unique patterns of UV-Vis absorptions and emissions.
10.1039/c7cc09743c
29,503,998
Chemical communications (Cambridge, England)
2,018
[Initial management of severe facial injuries].
Severe facial injuries may be treated within the first 12-h-period or delayed for several days while the patient is transferred to an appropriate hospital. The goal of treatment should be optimal primary reconstruction of all the damaged structures. Specialized experience, instruments and a well-equipped operative thea...
10.1007/BF01297909
3,431,287
D005147:Facial Bones; D005151:Facial Injuries; D005392:First Aid; D006801:Humans; D009104:Multiple Trauma; D012017:Referral and Consultation; D012086:Reoperation; D012151:Resuscitation
Langenbecks Archiv fur Chirurgie
1,987
Stochastic nucleation processes and substrate abundance explain time-dependent freezing in supercooled droplets.
Atmospheric immersion freezing (IF), a heterogeneous ice nucleation process where an ice nucleating particle (INP) is immersed in supercooled water, is a dominant ice formation pathway impacting the hydrological cycle and climate. Implementation of IF derived from field and laboratory data in cloud and climate models i...
10.1038/s41612-020-0106-4
32,754,650
NPJ climate and atmospheric science
2,020
Outlining the Complex Pathway of Mammalian Fe-S Cluster Biogenesis.
Iron-sulfur (Fe-S) clusters (ISCs) are ubiquitous cofactors essential to numerous fundamental cellular processes. Assembly of ISCs and their insertion into apoproteins involves the function of complex cellular machineries that operate in parallel in the mitochondrial and cytosolic/nuclear compartments of mammalian cell...
10.1016/j.tibs.2020.02.001
32,311,335
D003600:Cytosol; D004247:DNA; D007506:Iron-Sulfur Proteins; D008928:Mitochondria; D012313:RNA
Trends in biochemical sciences
2,020
D007506:Iron-Sulfur Proteins; D012313:RNA; D004247:DNA
[Correlation between the organoleptic evaluation and the laboratory analysis of white brined cheese].
Satisfactory correlation was found to exist between the organoleptic evaluation and the chemical analysis of ewe's and cow's white brine cheese on the basis of the taste assessment for "normal acidity", while with the remaining degrees of acidity--"slightly acid", and "strongly acid"--no such correlation was establishe...
1,025,842
D000818:Animals; D002031:Bulgaria; D002417:Cattle; D002611:Cheese; D012756:Sheep
Veterinarno-meditsinski nauki
1,976
Assessing fuel treatment effectiveness using satellite imagery and spatial statistics.
Understanding the influences of forest management practices on wildfire severity is critical in fire-prone ecosystems of the western United States. Newly available geospatial data sets characterizing vegetation, fuels, topography, and burn severity offer new opportunities for studying fuel treatment effectiveness at re...
10.1890/08-1685.1
19,769,087
D017753:Ecosystem; D005390:Fires; D016468:Forestry; D040362:Geographic Information Systems; D014481:United States; D014887:Weather
Ecological applications : a publication of the Ecological Society of America
2,009
How should individual participant data (IPD) from publicly funded clinical trials be shared?
BACKGROUND Individual participant data (IPD) from completed clinical trials should be responsibly shared to support efficient clinical research, generate new knowledge and bring benefit to patients. The Medical Research Council (MRC) Hubs for Trials Methodology Research (HTMR) has developed guidance to facilitate the s...
10.1186/s12916-015-0532-z
26,675,031
D002986:Clinical Trials as Topic; D005378:Financial Support; D017408:Guidelines as Topic; D006801:Humans; D033181:Information Dissemination; D011050:Policy Making
BMC medicine
2,015
Nanos2 suppresses meiosis and promotes male germ cell differentiation.
In mouse fetal gonads, retinoic acid (RA) induces meiosis in the female germ cells, whereas the male germ cells never enter meiosis due to Cyp26b1-mediated RA metabolism. We show here that Nanos2 plays critical roles in the differentiation of male germ cells. We find that Nanos2 maintains the suppression of meiosis by ...
10.1101/gad.1612708
18,281,459
D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D002352:Carrier Proteins; D002454:Cell Differentiation; D003577:Cytochrome P-450 Enzyme System; D004261:DNA Replication; D005260:Female; D005854:Germ Cells; D008297:Male; D008540:Meiosis; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D0115...
Genes & development
2,008
D048868:Adaptor Proteins, Signal Transducing; D002352:Carrier Proteins; C477341:Nanos2 protein, mouse; D011506:Proteins; D016601:RNA-Binding Proteins; C102019:Stra8 protein, mouse; D014212:Tretinoin; D003577:Cytochrome P-450 Enzyme System; C000607081:Cyp26b1 protein, mouse; D000072516:Retinoic Acid 4-Hydroxylase
Immunogenicity and safety of a novel AS03(A)-adjuvanted H1N1 2009 pandemic influenza vaccine in adults in Japan.
BACKGROUND AND OBJECTIVES This study evaluated the immunogenicity and safety of a novel H1N1 2009 pandemic vaccine(A/California/7/2009) in Japanese adults. RESULTS Following Dose 1, seroprotection rate (HI titre ≥1:40) was 95%, seroconversion rate was 94% and the geometric mean titre (GMT) was 230.3 (geometric mean f...
10.4161/hv.6.11.12851
20,980,795
D000276:Adjuvants, Immunologic; D000328:Adult; D000914:Antibodies, Viral; D044466:Asian People; D005260:Female; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007117:Immunization, Secondary; D053118:Influenza A Virus, H1N1 Subtype; D007252:Influenza Vaccines; D007251:Influenza, Human; D008297:Male; D008875...
Human vaccines
2,010
D000276:Adjuvants, Immunologic; D000914:Antibodies, Viral; D007252:Influenza Vaccines; D022223:Vaccines, Subunit
Short-term developmental toxicity and potential mechanisms of the herbicide metamifop to zebrafish (Danio rerio) embryos.
Metamifop is a novel aryloxyphenoxy propionate (AOPP) herbicide that is widely applied in paddy fields, which will inevitably enter aquatic environments and pose a risk to aquatic organisms. However, the potential threat and toxicological mechanisms of metamifop in aquatic organisms are poorly understood. In this study...
10.1016/j.chemosphere.2019.124590
31,470,984
D000813:Anilides; D000818:Animals; D017209:Apoptosis; D001583:Benzoxazoles; D004625:Embryo, Nonmammalian; D018507:Gene Expression Regulation, Developmental; D006540:Herbicides; D007113:Immunity, Innate; D007814:Larva; D018384:Oxidative Stress; D017382:Reactive Oxygen Species; D014874:Water Pollutants, Chemical; D015027...
Chemosphere
2,019
C522766:2-(4-(6-chloro-1,3-benzoxazol-2-yloxy)phenoxy)-2'-fluoro-N-methylpropionanilide; D000813:Anilides; D001583:Benzoxazoles; D006540:Herbicides; D017382:Reactive Oxygen Species; D014874:Water Pollutants, Chemical
Using the inflammatory cell infiltrate to estimate the age of human burn wounds: A review and immunohistochemical study.
UNLABELLED The burn wound healing process, which is reviewed in this paper, has features that differ from the healing of incised cutaneous wounds. This study used immunohistochemical staining and cell counting to examine the inflammatory cell response in biopsy samples of burn wounds from live human subjects obtained a...
10.1258/rsmmsl.46.2.115
16,683,466
D000293:Adolescent; D000328:Adult; D000368:Aged; D001344:Autopsy; D001706:Biopsy; D002056:Burns; D005122:Exudates and Transudates; D005260:Female; D049429:Forensic Pathology; D006801:Humans; D007150:Immunohistochemistry; D007249:Inflammation; D007962:Leukocytes; D008297:Male; D008875:Middle Aged; D014945:Wound Healing
Medicine, science, and the law
2,006
Bovine embryos contain a higher proportion of polyploid cells in the trophectoderm than in the embryonic disc.
The frequency of polyploid cells in the embryonic disc (ED) and in the trophectoderm (TE) was assessed in 50 in vitro produced bovine embryos fixed at days 7-8 post insemination (pi) and in 20 in vitro produced embryos that were transferred to uteri of recipients at day 7 and then recovered and fixed at day 12 pi. Sepa...
10.1002/mrd.90004
12,112,581
D000818:Animals; D001755:Blastocyst; D002417:Cattle; D004475:Ectoderm; D011123:Polyploidy
Molecular reproduction and development
2,002
[The influence of ultrasound and constant magnetic field on gametes, zygotes, and embryos of the sea urchin].
The influence of constant magnetic field, power 7 T, and ultrasound, frequency 2, 4 and 8 MHz, on gametes, fertization, embryos and larvae of the sea urchin was studied. It was shown that magnetic field breaks the process of the gamete fusion but does not influence gametes, embryos, and larvae. Ultrasound impairs the m...
18,634,327
D000818:Animals; D003599:Cytoskeleton; D004574:Electromagnetic Fields; D004625:Embryo, Nonmammalian; D005260:Female; D005306:Fertilization; D005854:Germ Cells; D008280:Magnetics; D008297:Male; D012617:Sea Urchins; D013075:Sperm Capacitation; D013094:Spermatozoa; D014465:Ultrasonics; D015053:Zygote
Biofizika
2,008
Immunomodulatory Properties of Water-Soluble Polysaccharides Extracted from the Fruiting Body of Chinese Caterpillar Mushroom, Ophiocordyceps sinensis Cultivar OCS02® (Ascomycetes).
Ophiocordyceps sinensis (=Cordyceps sinensis) has been known for its various medicinal properties, in particular immunomodulatory activities associated with its polysaccharides. In this study, the fruiting body of O. sinensis cultivar OCS02® was investigated for its chemical composition and monosaccharide profile. Cold...
10.1615/IntJMedMushrooms.2020036351
33,426,826
D000363:Agaricales; D000818:Animals; D002681:China; D016207:Cytokines; D048690:Fruiting Bodies, Fungal; D006999:Hypocreales; D007155:Immunologic Factors; D008264:Macrophages; D051379:Mice; D008970:Molecular Weight; D010936:Plant Extracts; D011134:Polysaccharides; D000067996:RAW 264.7 Cells
International journal of medicinal mushrooms
2,020
D016207:Cytokines; D007155:Immunologic Factors; D010936:Plant Extracts; D011134:Polysaccharides
Determination of L-dopa, carbidopa, 3-O-methyldopa and entacapone in human plasma by HPLC-ED.
The aim of the study was the development of analytical methods suitable for the quantification of L-dopa, carbidopa and entacapone in plasma of Parkinsonian patients treated with Stalevo(®). The metabolite 3-O-methyldopa was also determined to obtain some indications on the pharmacokinetics of L-dopa. For the simultane...
10.1016/j.jpba.2010.09.042
21,035,976
D000978:Antiparkinson Agents; D002138:Calibration; D002230:Carbidopa; D002396:Catechols; D002851:Chromatography, High Pressure Liquid; D004338:Drug Combinations; D006801:Humans; D007980:Levodopa; D008750:Methyldopa; D009570:Nitriles; D015203:Reproducibility of Results; D052616:Solid Phase Extraction
Journal of pharmaceutical and biomedical analysis
2,011
D000978:Antiparkinson Agents; D002396:Catechols; D004338:Drug Combinations; D009570:Nitriles; C481098:Stalevo; D007980:Levodopa; C071192:entacapone; D008750:Methyldopa; D002230:Carbidopa
Targeted and passive environmental DNA approaches outperform established methods for detection of quagga mussels, Dreissena rostriformis bugensis in flowing water.
The early detection of invasive non-native species (INNS) is important for informing management actions. Established monitoring methods require the collection or observation of specimens, which is unlikely at the beginning of an invasion when densities are likely to be low. Environmental DNA (eDNA) analysis is a highly...
10.1002/ece3.6921
33,304,534
Ecology and evolution
2,020
The Council on Clinical Optometric Care (CCOC): The American Optometric Association's Institutional-Practice Reviewer 1967-1993.
BACKGROUND For 26 years the CCOC served professional optometry as its institutional-practice reviewer. METHODS The council used nine standards for accrediting clinical institutions. RESULTS The benefits of the accreditation process were many, with improved patient care as its cornerstone. CONCLUSION During its 26...
8,014,370
D000068:Accreditation; D006801:Humans; D009907:Optometry; D011366:Professional Review Organizations; D012952:Societies; D014481:United States
Journal of the American Optometric Association
1,994
The burden of acute renal failure in nonrenal solid organ transplantation.
BACKGROUND Recipients of nonrenal solid organ transplants are at risk for acute renal failure resulting from cardiac or hepatic failure, prolonged surgery, and nephrotoxic effects of immunosuppression. Single-center studies have suggested a variable incidence of acute renal failure in this population, with an associate...
10.1097/01.tp.0000140848.05002.b8
15,548,974
D058186:Acute Kidney Injury; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D015994:Incidence; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D016377:Organ Transplantation
Transplantation
2,004
Relationship of Brain Glutamate Response to D-Cycloserine and Lurasidone to Antidepressant Response in Bipolar Depression: A Pilot Study.
N-methyl-D-aspartate glutamate-receptor (NMDAR) antagonists such as ketamine have demonstrated efficacy in both major depressive disorder (MDD) and bipolar disorder depression (BP-D). We have previously reported that reduction in Glx (glutamate + glutamine) in the ventromedial prefrontal cortex/anterior cingulate corte...
10.3389/fpsyt.2021.653026
34,149,476
Frontiers in psychiatry
2,021
Social media addiction, cyberbullying and cyber victimization of university students.
AIM The study was conducted descriptively to determine the social media addiction, cyberbullying (CB) and cyber victimization (CV) of health sciences faculty students. METHOD 518 students who volunteered to participate in the study from among the students studying in the faculty of health sciences. The personal infor...
10.1016/j.apnu.2021.07.004
34,561,065
D058445:Bullying; D019548:Crime Victims; D000077224:Cyberbullying; D005260:Female; D006801:Humans; D020407:Internet; D000082424:Internet Addiction Disorder; D008297:Male; D013334:Students; D014495:Universities
Archives of psychiatric nursing
2,021
The Memory Orchestra: Contribution of Astrocytes.
For decades, memory research has centered on the role of neurons, which do not function in isolation. However, astrocytes play important roles in regulating neuronal recruitment and function at the local and network levels, forming the basis for information processing as well as memory formation and storage. In this re...
10.1007/s12264-023-01024-x
36,738,435
D001253:Astrocytes; D009473:Neuronal Plasticity; D008568:Memory; D009474:Neurons; D003071:Cognition
Neuroscience bulletin
2,023
Estrogenic Modulation of Ionic Channels, Pumps and Exchangers in Airway Smooth Muscle.
To preserve ionic homeostasis (primarily Ca2+, K+, Na+, and Cl-), in the airway smooth muscle (ASM) numerous transporters (channels, exchangers, and pumps) regulate the influx and efflux of these ions. Many of intracellular processes depend on continuous ionic permeation, including exocytosis, contraction, metabolism, ...
10.3390/ijms24097879
37,175,587
D002118:Calcium; D032389:Myocytes, Smooth Muscle; D009119:Muscle Contraction; D009130:Muscle, Smooth; D007473:Ion Channels; D004967:Estrogens
International journal of molecular sciences
2,023
D002118:Calcium; D007473:Ion Channels; D004967:Estrogens
Effects of race and ethnicity on the incidence of venous thromboembolism.
Although there is strong evidence that the prevalence of venous thrombo-embolism (VTE) varies significantly among different ethnic/racial groups, the genetic, physiologic and/or clinical basis for these differences remain largely undefined. African-American patients have a significantly higher rate of incident VTE, par...
10.1016/S0049-3848(09)70136-7
19,303,496
D000293:Adolescent; D000328:Adult; D001741:Black or African American; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants; D044466:Asian People; D002140:California; D005260:Female; D005343:Fibrinolytic Agents; D054624:Health Status Disparities; D006630:Hispanic or Latino; D006801:Humans...
Thrombosis research
2,009
D000925:Anticoagulants; D005343:Fibrinolytic Agents
Kinetic and thermodynamic parameters for Schiff base formation of vitamin B6 derivatives with amino acids.
Thermodynamic and kinetic parameters for Schiff base formation of pyridoxal 5'-phosphate and pyridoxal with epsilon-aminocaproic acid as well as of pyridoxal 5'-phosphate with L-serine were obtained in 0.1 M sodium pyrophosphate buffer as a function of temperature. Changes in enthalpy, which were determined by direct m...
10.1016/0003-9861(84)90252-2
6,437,337
D000596:Amino Acids; D015119:Aminocaproic Acid; D007700:Kinetics; D011730:Pyridoxal; D011732:Pyridoxal Phosphate; D011736:Pyridoxine; D012545:Schiff Bases; D012694:Serine; D013816:Thermodynamics
Archives of biochemistry and biophysics
1,984
D000596:Amino Acids; D012545:Schiff Bases; D011730:Pyridoxal; D012694:Serine; D011732:Pyridoxal Phosphate; D011736:Pyridoxine; D015119:Aminocaproic Acid
Novel innate cancer killing activity in humans.
BACKGROUND In this study, we pilot tested an in vitro assay of cancer killing activity (CKA) in circulating leukocytes of 22 cancer cases and 25 healthy controls. METHODS Using a human cervical cancer cell line, HeLa, as target cells, we compared the CKA in circulating leukocytes, as effector cells, of cancer cases a...
10.1186/1475-2867-11-26
21,813,015
Cancer cell international
2,011
Effects of SARS-CoV-2 Alpha, Beta, and Delta variants, age, vaccination, and prior infection on infectiousness of SARS-CoV-2 infections.
In 2021, Qatar experienced considerable incidence of SARS-CoV-2 infection that was dominated sequentially by the Alpha, Beta, and Delta variants. Using the cycle threshold (Ct) value of an RT-qPCR-positive test to proxy the inverse of infectiousness, we investigated infectiousness of SARS-CoV-2 infections by variant, a...
10.3389/fimmu.2022.984784
36,177,014
D000293:Adolescent; D000086382:COVID-19; D002648:Child; D006801:Humans; D011780:Qatar; D000086402:SARS-CoV-2; D014611:Vaccination; D055815:Young Adult
Frontiers in immunology
2,022
Nephronophthisis: a genetically diverse ciliopathy.
Nephronophthisis (NPHP) is an autosomal recessive cystic kidney disease and a leading genetic cause of established renal failure (ERF) in children and young adults. Early presenting symptoms in children with NPHP include polyuria, nocturia, or secondary enuresis, pointing to a urinary concentrating defect. Renal ultras...
10.4061/2011/527137
21,660,307
International journal of nephrology
2,011
A 12-month study of dialectical behavioral therapy for bοrderline patients suffering from eating disorders.
PURPOSE Individuals with eating disorders (ED) and comorbid borderline personality disorder (BPD) may benefit from therapies focusing on emotion regulation, such as dialectical behavioral therapy (DBT). The aim of the study was to evaluate the effectiveness of one-year standard DΒΤ enhanced with cognitive-behavioral th...
10.1007/s40519-023-01612-w
37,798,605
D006801:Humans; D001521:Behavior Therapy; D011613:Psychotherapy; D015928:Cognitive Behavioral Therapy; D001068:Feeding and Eating Disorders; D052018:Bulimia Nervosa; D016896:Treatment Outcome
Eating and weight disorders : EWD
2,023
Monitoring human enteric viruses in wastewater and relevance to infections encountered in the clinical setting: a one-year experiment in central France, 2014 to 2015.
BackgroundHuman enteric viruses are resistant in the environment and transmitted via the faecal-oral route. Viral shedding in wastewater gives the opportunity to track emerging pathogens and study the epidemiology of enteric infectious diseases in the community. Aim: The aim of this study was to monitor the circulation...
10.2807/1560-7917.ES.2018.23.7.17-00237
29,471,623
D004770:Enterovirus; D004769:Enterovirus Infections; D004784:Environmental Monitoring; D005243:Feces; D005602:France; D006801:Humans; D010865:Pilot Projects; D020133:Reverse Transcriptase Polymerase Chain Reaction; D062065:Wastewater; D014871:Water Microbiology
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
2,018
D062065:Waste Water
Correction: Dynamical self-assembly of dipolar active Brownian particles in two dimensions.
Correction for 'Dynamical self-assembly of dipolar active Brownian particles in two dimensions' by Guo-Jun Liao et al., Soft Matter, 2020, 16, 2208-2223, DOI: .
10.1039/d0sm90129f
32,617,546
Soft matter
2,020
Beta2-adrenergic receptor signaling in CD4+ Foxp3+ regulatory T cells enhances their suppressive function in a PKA-dependent manner.
Beta2-adrenergic receptor (B2AR) signaling is known to impair Th1-cell differentiation and function in a cAMP-dependent way, leading to inhibition of cell proliferation and decreased production of IL-2 and IFN-γ. CD4(+) Foxp3(+) Treg cells play a key role in the regulation of immune responses and are essential for main...
10.1002/eji.201243005
23,436,577
D000818:Animals; D015704:CD4 Antigens; D060908:CTLA-4 Antigen; D017868:Cyclic AMP-Dependent Protein Kinases; D051858:Forkhead Transcription Factors; D007376:Interleukin-2; D008213:Lymphocyte Activation; D051379:Mice; D018345:Mice, Knockout; D018343:Receptors, Adrenergic, beta-2; D015398:Signal Transduction; D050378:T-L...
European journal of immunology
2,013
D015704:CD4 Antigens; D060908:CTLA-4 Antigen; D051858:Forkhead Transcription Factors; C498833:Foxp3 protein, mouse; D007376:Interleukin-2; D018343:Receptors, Adrenergic, beta-2; D017868:Cyclic AMP-Dependent Protein Kinases
Chronic aorto-right ventricular fistula following penetrating cardiac injury: A case report.
Aorto-cardiac fistula is a rare but potentially life-threatening condition. We herein report a rare case of chronic aorto-right ventricular fistula formation secondary to a stab penetrating injury to the heart and aorta occurred 15 years ago. The aorto-right ventricular fistula was not found until 15 years after the in...
10.1111/echo.14876
32,989,811
D001011:Aorta; D005402:Fistula; D006335:Heart Injuries; D006352:Heart Ventricles; D006801:Humans; D016157:Vascular Fistula; D014951:Wounds, Stab
Echocardiography (Mount Kisco, N.Y.)
2,020
Pressure distribution on the wall of experimental aneurysms.
Since it is known that turbulent flow exists in aneurysms, we have investigated whether pressure might be distributed unevenly on the aneurysmal wall, and whether it varies with the shape and size of the aneurysm and its orifice diameter as well as with the direction of blood flow in the parent vessel. It was found tha...
10.1007/BF01774381
742,437
D000818:Animals; D001696:Biomechanical Phenomena; D001794:Blood Pressure; D002415:Cats; D004195:Disease Models, Animal; D002532:Intracranial Aneurysm
Acta neurochirurgica
1,978
Efficacy of racism-specific coping styles as predictors of cardiovascular functioning.
OBJECTIVE This study examined the relationship between racism-specific coping strategies and cardiovascular responses to an ethnically relevant speaking task. METHODS Fifty-seven African-American females participated in a speaking task during which they discussed their experiences with inter-ethnic group racism. Bloo...
11,456,003
D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D001741:Black or African American; D001794:Blood Pressure; D005260:Female; D006339:Heart Rate; D006801:Humans; D015999:Multivariate Analysis; D011287:Prejudice
Ethnicity & disease
2,001
Fast-track cardiac anaesthesia in the elderly: effect of two different anaesthetic techniques on mental recovery.
Elderly patients may be considered for 'fast-track' cardiac anaesthesia, but can suffer psychological complications and slow recovery of mental function after surgery, which can interfere with recovery. Reduced metabolism and changed distribution of anaesthetic and sedative agents can cause poor recovery. We made a pro...
10.1093/bja/86.1.68
11,575,413
D000368:Aged; D000768:Anesthesia, General; D018686:Anesthetics, Intravenous; D014151:Anti-Anxiety Agents; D003072:Cognition Disorders; D003243:Consciousness; D001026:Coronary Artery Bypass; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007902:Length of Stay; D008140:Lorazepam; D008297:Male; D008874:Midazolam; ...
British journal of anaesthesia
2,001
D018686:Anesthetics, Intravenous; D014151:Anti-Anxiety Agents; D008140:Lorazepam; D008874:Midazolam; D015742:Propofol
MiRNA profiling of gastrointestinal stromal tumors by next-generation sequencing.
Deregulation of miRNAs has been observed virtually in all major types of cancer, whereas the miRNA signature in GIST is not well characterized yet. In this study the first high-throughput miRNA profiling of 15 paired GIST and adjacent normal tissue samples was performed using small RNA-seq approach and differentially e...
10.18632/oncotarget.16664
28,402,935
D000368:Aged; D005260:Female; D005770:Gastrointestinal Neoplasms; D046152:Gastrointestinal Stromal Tumors; D020869:Gene Expression Profiling; D015972:Gene Expression Regulation, Neoplastic; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D008297:Male; D035683:MicroRNAs; D008875:Middle Aged; D020411:Oligo...
Oncotarget
2,017
D035683:MicroRNAs; D019009:Proto-Oncogene Proteins c-kit; D020796:Receptor, Platelet-Derived Growth Factor alpha
Recycling Waste Polyester via Modification with a Renewable Fatty Acid for Enhanced Processability.
Polyethylene terephthalate (PET) waste often contains a large amount of thermally unstable contaminants and additives that negatively impacts processing. A reduced processing temperature is desired. In this work, we report using a renewably sourced tall oil fatty acid (TOFA) as a modifier for recycled PET. To that end,...
10.1021/acsomega.8b00598
31,459,188
ACS omega
2,018
Strategies of Recovery and Organic Recycling Used in Textile Waste Management.
Post-consumer bio-based textile wastes are any type of garment or household article made from manufactured bio-based textiles that the owner no longer needs and decides to discard. According to the hierarchy of waste management, post-consumer textile waste should be organically recycled. However, there is still a probl...
10.3390/ijerph19105859
35,627,395
D004043:Dietary Fiber; D010969:Plastics; D059027:Recycling; D013784:Textiles; D018505:Waste Management; D014866:Waste Products
International journal of environmental research and public health
2,022
D004043:Dietary Fiber; D010969:Plastics; D014866:Waste Products
Cytokine-modified tumor vaccines: an antitumor strategy revisited in the age of molecular medicine.
Technological advances and improved understanding of the biology of the immune response have resulted in a resurgence of interest in the use of tumor vaccination as a means to control cancer. Tumor vaccines genetically modified with cytokine genes comprise the greatest proportion of gene therapy approaches to cancer. T...
10.1097/00002820-199806000-00003
9,615,507
D019496:Cancer Vaccines; D016207:Cytokines; D015316:Genetic Therapy; D006801:Humans; D006968:Hypersensitivity, Delayed; D007167:Immunotherapy; D007271:Injections, Intradermal; D009369:Neoplasms; D009859:Oncology Nursing; D012882:Skin Tests; D014161:Transduction, Genetic; D014407:Tumor Cells, Cultured
Cancer nursing
1,998
D019496:Cancer Vaccines; D016207:Cytokines
High pre-therapy [99mTc]pertechnetate thyroid uptake, thyroid size and thyrostatic drugs: predictive factors of failure in [131I]iodide therapy in Graves' disease.
BACKGROUND AND OBJECTIVE Several factors may interfere with the success rate of radioiodine therapy (RIT) in Graves' disease. Our aim was to evaluate, retrospectively, some of these factors in the outcome of RIT. METHODS Patient gender, age at diagnosis, ophthalmopathy, disease duration, thyroid size, drug used as cl...
10.1097/01.mnm.0000183795.59097.42
16,208,172
D000293:Adolescent; D000328:Adult; D000368:Aged; D013956:Antithyroid Agents; D001938:Brazil; D002648:Child; D005260:Female; D006111:Graves Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011379:Prognosis; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012189:Retrospective ...
Nuclear medicine communications
2,005
D013956:Antithyroid Agents; D019275:Radiopharmaceuticals; D013670:Sodium Pertechnetate Tc 99m
[Comparative studies on the amount of ginsenosides between the crown galls and Chinese medicinal materials of Panax quinquefolium].
OBJECTIVE To provide theoretical basis for the production of ginsenosides by using modern biotechnologies, the comparative studies of the amount of ginsenosides between the crown galls and Chinese medicinal materials of Panax quinquefolium were carried out. METHODS Total ginsenosides were determined by spectrophotome...
19,771,838
D002851:Chromatography, High Pressure Liquid; D036145:Ginsenosides; D005894:Panax; D010598:Pharmacognosy; D018517:Plant Roots; D030821:Plants, Genetically Modified; D010946:Plants, Medicinal; D011786:Quality Control; D015203:Reproducibility of Results; D046509:Tissue Culture Techniques
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
2,009
D036145:Ginsenosides
From contact electrification to triboelectric nanogenerators.
Although the contact electrification (CE) (or usually called 'triboelectrification') effect has been known for over 2600 years, its scientific mechanism still remains debated after decades. Interest in studying CE has been recently revisited due to the invention of triboelectric nanogenerators (TENGs), which are the mo...
10.1088/1361-6633/ac0a50
34,111,846
Reports on progress in physics. Physical Society (Great Britain)
2,021
Latrunculin resistance mechanism of non-conventional actin NAP1 uncovered by molecular dynamics simulations.
Monomeric G-actin polymerizes into F-actin to perform various cellular functions. Actin depolymerization drugs, such as latrunculin-A (Lat-A), inhibit filament formation and disrupt the cytoskeleton. Interestingly, the green algae Chlamydomonas alternatively produces a non-conventional actin, NAP1, that responds to inh...
10.1002/cm.21798
37,815,120
Cytoskeleton (Hoboken, N.J.)
2,023
CRb and PbBa8.1 Synergically Increases Resistant Genes Expression upon Infection of Plasmodiophora brassicae in Brassica napus.
PbBa8.1 and CRb are two clubroot-resistant genes that are important for canola breeding in China. Previously, we combined these resistant genes and developed a pyramid-based, homozygous recurrent inbred line (618R), the results of which showed strong resistance to Plasmodiophora brassicae field isolates; however, the g...
10.3390/genes11020202
32,079,196
D029688:Brassica napus; D060467:Disease Resistance; D020869:Gene Expression Profiling; D005786:Gene Expression Regulation; D053263:Gene Regulatory Networks; D023281:Genomics; D000069600:Plant Breeding; D010935:Plant Diseases; D010940:Plant Proteins; D056909:Plasmodiophorida; D017423:Sequence Analysis, RNA
Genes
2,020
D010940:Plant Proteins
Conformational flexibility of a free and TCR-bound pMHC-I protein investigated by long-term molecular dynamics simulations.
BACKGROUND Major histocompatibility complexes (MHCs) play a crucial role in the cell-mediated adaptive immune response as they present antigenic peptides (p) which are recognized by host T cells through a complex formation of the T cell receptor (TCR) with pMHC. In the present study, we report on changes in conformatio...
10.1186/s12865-022-00510-7
35,902,791
D006649:Histocompatibility Antigens; D056004:Molecular Dynamics Simulation; D010455:Peptides; D011485:Protein Binding; D011487:Protein Conformation; D011948:Receptors, Antigen, T-Cell
BMC immunology
2,022
D006649:Histocompatibility Antigens; D010455:Peptides; D011948:Receptors, Antigen, T-Cell
Computationally Designed Anti-LuxP DNA Aptamer Suppressed Flagellar Assembly- and Quorum Sensing-Related Gene Expression in Vibrio parahaemolyticus.
(1) Background: Quorum sensing (QS) is the chemical communication between bacteria that sense chemical signals in the bacterial population to control phenotypic changes through the regulation of gene expression. The inhibition of QS has various potential applications, particularly in the prevention of bacterial infecti...
10.3390/biology11111600
36,358,301
Biology
2,022
The effects of psychological treatment of maternal depression on children and parental functioning: a meta-analysis.
Successful treatment of parental depression may have a positive effect on the functioning and psychopathology of their children. We conducted a meta-analysis to examine the effects of psychotherapy for depressed mothers on their children and parental functioning. We used a database of randomized controlled trials exami...
10.1007/s00787-014-0660-6
25,522,839
D000328:Adult; D002648:Child; D016241:Child of Impaired Parents; D003863:Depression; D005190:Family; D005260:Female; D006801:Humans; D008297:Male; D008603:Mental Health; D009034:Mother-Child Relations; D009035:Mothers; D016487:Parenting; D011599:Psychopathology; D011613:Psychotherapy; D016896:Treatment Outcome
European child & adolescent psychiatry
2,015
A functional and histopathological comparison of proximal and distal saphenous vein contractility and morphology.
Variations in vascular reactivity and morphology of proximal and distal saphenous vein might affect its performance as a bypass conduit. Because peri- or postoperative graft spasm or intimal hyperplasia reduces patency, we compared the reactivity and morphology of human proximal and distal saphenous vein conduits. Isom...
16,392,207
D000368:Aged; D001026:Coronary Artery Bypass; D003327:Coronary Disease; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D011189:Potassium Chloride; D012501:Saphenous Vein; D018608:Ultrasonography, Doppler; D014661:Vasoconstriction; D014662:Vasoconstrictor Agents
Texas Heart Institute journal
2,005
D014662:Vasoconstrictor Agents; D011189:Potassium Chloride
Intermittent propofol sedation during embolization of cerebral arteriovenous malformations.
Embolization procedure was performed for a 12-year-old boy with a left parietal arteriovenous malformation. Although provocative tests for the feeders to be occluded were considered very informative, the patient had to be sedated during microcatheter insertion. We used intermittent sedation with propofol during the int...
10.1097/00008506-200001000-00010
10,636,621
D018686:Anesthetics, Intravenous; D001672:Biocompatible Materials; D002404:Catheterization; D002482:Cellulose; D002560:Cerebrovascular Circulation; D002648:Child; D003097:Collateral Circulation; D016292:Conscious Sedation; D004621:Embolization, Therapeutic; D006801:Humans; D006993:Hypnotics and Sedatives; D002538:Intra...
Journal of neurosurgical anesthesiology
2,000
D018686:Anesthetics, Intravenous; D001672:Biocompatible Materials; D006993:Hypnotics and Sedatives; C005062:acetylcellulose; D002482:Cellulose; D015742:Propofol
Perfect imaging with planar interfaces.
We describe the most general homogenous, planar, light-ray-direction-changing sheet that performs one-to-one imaging between object space and image space. This is a nontrivial special case (of the sheet being homogenous) of an earlier result [Opt. Commun.282, 2480 (2009)]. Such a sheet can be realized, approximately, w...
10.1364/JOSAA.30.002334
24,322,933
Journal of the Optical Society of America. A, Optics, image science, and vision
2,013
Global longitudinal strain differentiates physiological hypertrophy from maladaptive remodeling.
Aims Differentiation of left ventricular (LV) hypertrophy in healthy athletes from pathological LV hypertrophy in heart disease is often difficult. We explored whether extended echocardiographic measurements such as E/e' and global longitudinal strain (GLS) distinguish physiologic from maladaptive hypertrophy in hypert...
10.1016/j.ijcha.2022.101044
35,573,652
International journal of cardiology. Heart & vasculature
2,022
Tetanically released zinc inhibits hippocampal mossy fiber calcium, zinc and synaptic responses.
At the zinc-enriched mossy fiber synapses from hippocampal CA3 area, electrical or chemical stimulation evokes zinc release from glutamatergic synaptic vesicles that may cause different pre- or postsynaptic actions. Besides zinc that can be co-localized with glutamate and GABA, the mossy fibers contain a very high dens...
10.1016/j.brainres.2005.04.006
15,950,598
D000255:Adenosine Triphosphate; D000634:Aminoquinolines; D000818:Animals; D002118:Calcium; D020013:Calcium Signaling; D002614:Chelating Agents; D004558:Electric Stimulation; D018690:Excitatory Amino Acid Agonists; D005456:Fluorescent Dyes; D016257:Fura-2; D007202:Indicators and Reagents; D017774:Long-Term Potentiation;...
Brain research
2,005
D000634:Aminoquinolines; D002614:Chelating Agents; D018690:Excitatory Amino Acid Agonists; D005456:Fluorescent Dyes; D007202:Indicators and Reagents; D024661:Potassium Channels, Inwardly Rectifying; D014105:Tosyl Compounds; C061730:N-(6-methoxy-8-quinolyl)-4-toluenesulfonamide; D000255:Adenosine Triphosphate; D015032:Z...
Rates of 5 common antidepressant side effects among new adult and adolescent cases of depression: a retrospective US claims study.
BACKGROUND Antidepressants are the first-line treatment for depression, yet medication-related side effects may be associated with antidepressant discontinuation before reaching a period of exposure believed to result in effectiveness. There is a gap in knowledge of the prevalence of side effects across commonly prescr...
10.1016/j.clinthera.2011.11.024
22,177,545
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000928:Antidepressive Agents; D019992:Databases as Topic; D003863:Depression; D006261:Headache; D006801:Humans; D008329:Managed Care Programs; D008875:Middle Aged; D009325:Nausea; D015995:Prevalence; D057216:Propensity Score; D016016:Proportional Hazards Models; ...
Clinical therapeutics
2,012
D000928:Antidepressive Agents
Insensible water loss from the medtronic minimax oxygenator: an In Vitro study.
The purposes of this study were to quantify the insensible water loss that occurs across the Medtronic Minimax oxygenator and to estimate the resultant rise in fluid sodium concentration.A Carmeda-coated extracorporeal membrane oxygenation circuit connected to a Medtronic Minimax Plus oxygenator was primed with normal ...
10.1097/01.mat.0000202275.72712.47
16,557,110
D015199:Extracorporeal Membrane Oxygenation; D066298:In Vitro Techniques; D012964:Sodium; D014870:Water Loss, Insensible
ASAIO journal (American Society for Artificial Internal Organs : 1992)
2,006
D012964:Sodium
[Lupus nephritis with crystal structures in glomerulopathy ].
Lupus nephritis is a common phenomenon in Systemic Lupus Erythematosus (SLE). We analyzed a renal biopsy of a 30-year-old woman with SLE. The clinical history showed a typical SLE with generalized symptoms without demonstrable lupus coagulant, positive for anti-nuclear antibodies and anti-ds-DNA antibodies but negative...
10.1007/s00292-003-0658-1
14,605,847
D000328:Adult; D003460:Crystallization; D005260:Female; D005921:Glomerulonephritis; D006801:Humans; D007150:Immunohistochemistry; D007678:Kidney Glomerulus; D008181:Lupus Nephritis; D016253:Microscopy, Immunoelectron
Der Pathologe
2,003
Association Between Metabolic Syndrome, Its Components, and Knee Osteoarthritis in Premenopausal and Menopausal Women: A Pilot Study.
OBJECTIVE This pilot study aimed to determine the correlation of metabolic syndrome (MetS), its components, and increased LDL (low-density lipoprotein) and total cholesterol levels with osteoarthritis (OA). In addition, our goal was to establish the association between MetS and the degree of handicap measured by the Le...
10.7759/cureus.26726
35,967,163
Cureus
2,022
Hierarchical TiO2 microspheres composed with nanoparticle-decorated nanorods for the enhanced photovoltaic performance in dye-sensitized solar cells.
Hierarchical TiO2 microspheres composed of nanoparticle-decorated nanorods (NP-MS) were successfully prepared with a two-step solvothermal method. There were three benefits associated with the use of NP-MS as a photoanode material. The decoration of nanoparticles improved the specific surface area and directly enhanced...
10.1039/c8ra09145e
35,518,992
RSC advances
2,019
Impact of Dentine Pretreatment with Matrix Metalloproteinase Inhibitors on Bond Strength of Coronal Composite Restorations: A Systematic Review and Meta-analysis of In Vitro Studies.
OBJECTIVES Matrix metalloproteinase (MMP) enzymes participate in collagen matrix degradation, including in dentine, potentially compromising bond strength. Therefore, MMP inhibitors have been hypothesized to improve restoration bond strength and stability. This systematic review aimed to evaluate the influence of diffe...
10.1055/s-0042-1757582
36,400,108
European journal of dentistry
2,022
Fetal intracardiac potassium chloride injection to avoid the hopeless resuscitation of an abnormal abortus: II. Ethical issues.
Following the diagnosis of a genetic anomaly, some couples choose to have a legal abortion. However, following later abortions at greater than 20 weeks, the rare but catastrophic occurrence of live births can lead to fractious controversy over neonatal management. To avoid this situation, we have added fetal intracardi...
1,635,751
D000025:Abortion, Eugenic; D000013:Congenital Abnormalities; D004992:Ethics, Medical; D005260:Female; D005318:Fetal Heart; D006324:Heart Arrest, Induced; D006801:Humans; D007267:Injections; D007751:Labor, Induced; D011189:Potassium Chloride; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D012151:Resuscitation
Obstetrics and gynecology
1,992
D011189:Potassium Chloride
TRANSFUSION REACTIONS: AFMC EXPERIENCE.
Transfusions of blood and its components are useful and lifesaving. Adverse effects occur during or after transfusion, called hazards or complications of blood transfusion. Complications/hazards of various types which occurred in the patients following transfusion of blood/blood components in Armed Forces Hospitals of ...
10.1016/S0377-1237(17)30258-7
28,775,593
Medical journal, Armed Forces India
1,999
Effect of key design parameters on bacteria community and effluent pollutant concentrations in constructed wetlands using mathematical models.
Constructed wetlands are currently recognized as an effective environmental biotechnology for wastewater treatment, but the influence of their design parameters on internal functioning and contaminant removal efficiency is still under discussion. In this work, the effect of aspect ratio and water depth on bacteria comm...
10.1016/j.scitotenv.2017.01.014
28,122,686
D001419:Bacteria; D008962:Models, Theoretical; D009584:Nitrogen; D014865:Waste Disposal, Fluid; D062065:Wastewater; D014871:Water Microbiology; D014874:Water Pollutants, Chemical; D053833:Wetlands
The Science of the total environment
2,017
D062065:Waste Water; D014874:Water Pollutants, Chemical; D009584:Nitrogen
When Does the Knee Feel Normal Again: A Cross-Sectional Study Assessing the Forgotten Joint Score in Patients After Total Knee Arthroplasty.
BACKGROUND The forgotten joint score (FJS) is a recent scoring system that assesses how natural the prosthesis feels after total joint arthroplasty. Although the FJS has been extensively applied in populations with total hip prosthetics, less is known about the patients undergoing total knee arthroplasty (TKA). The pur...
10.1016/j.arth.2017.09.063
29,108,793
D000368:Aged; D019645:Arthroplasty, Replacement, Knee; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007717:Knee; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D009985:Orthopedics; D011184:Postoperative Period; D020127:Recovery of Function...
The Journal of arthroplasty
2,018
The Establishment of a Tobramycin-Responsive Whole-Cell Micro-Biosensor Based on an Artificial Ribozyme Switch.
In this study, a tobramycin concentration-dependent whole-cell micro-biosensor (tob-HHAz) was constructed by fusing a tobramycin aptamer with a hammerhead ribozyme (HHR) from Schistosoma mansoni. The biosensor was obtained by integrating all the modules into one complete RNA sequence, which was easily introduced into E...
10.3390/life13071553
37,511,928
Life (Basel, Switzerland)
2,023
Scoping Review and Meta-Analysis Suggests that Cannabis Use May Reduce Cancer Risk in the United States.
Introduction:Cannabis smoke contains carcinogens similar to tobacco, in addition to compounds with antitumor activity. Cannabis use reduces the risk of obesity and cannabinoids inhibit chronic inflammation, known causes of cancer. The net effect of Cannabis use on cancer risk is not known. Objective: To examine the ass...
10.1089/can.2019.0095
33,998,861
D002186:Cannabinoids; D002188:Cannabis; D006213:Hallucinogens; D006801:Humans; D008297:Male; D012306:Risk; D013736:Testicular Neoplasms; D014481:United States
Cannabis and cannabinoid research
2,021
D002186:Cannabinoids; D006213:Hallucinogens
Effects of a combined parent-student alcohol prevention program on intermediate factors and adolescents' drinking behavior: A sequential mediation model.
OBJECTIVE Previous work revealed that the combined parent-student alcohol prevention program (PAS) effectively postponed alcohol initiation through its hypothesized intermediate factors: increase in strict parental rule setting and adolescents' self-control (Koning, van den Eijnden, Verdurmen, Engels, & Vollebergh, 201...
10.1037/a0039197
25,939,019
D000293:Adolescent; D000294:Adolescent Behavior; D000328:Adult; D000428:Alcohol Drinking; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008960:Models, Psychological; D017008:Negotiating; D009426:Netherlands; D010290:Parents; D000068356:Self-Control; D013334:Students
Journal of consulting and clinical psychology
2,015
Interleukin-12 inhibits eotaxin secretion of cultured primary lung cells and alleviates airway inflammation in vivo.
The mechanisms that cause the inflammation of airway and lung tissue in asthma have been studied extensively. It is noted that type 1T helper cell (Th1)-related cytokines could decrease the accumulation of eosinophils in lung tissue and relieve airway constriction. But the therapeutic mechanisms of Th1 cytokines remain...
10.1006/cyto.2002.1950
12,182,842
D000818:Animals; D001249:Asthma; D001980:Bronchi; D054413:Chemokine CCL11; D019742:Chemokines, CC; D004195:Disease Models, Animal; D007249:Inflammation; D018664:Interleukin-12; D008081:Liposomes; D008168:Lung; D051379:Mice; D008810:Mice, Inbred C57BL; D010957:Plasmids; D014132:Trachea; D014162:Transfection
Cytokine
2,002
C515457:Ccl11 protein, mouse; D054413:Chemokine CCL11; D019742:Chemokines, CC; D008081:Liposomes; D018664:Interleukin-12
Subdural hygroma-related heterotopic ossification in a patient with a stroke: a case report.
BACKGROUND This study presents a patient with a stroke who had total paralysis of his left-side limbs after intracranial haemorrhaging, who later experienced partial weakness of the right-side limbs after a subdural hygroma. Both conditions occurred without major trauma. He received two separate operations, a craniotom...
10.3109/02699052.2011.571228
21,534,740
D003399:Craniotomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009999:Ossification, Heterotopic; D010243:Paralysis; D020521:Stroke; D013353:Subdural Effusion; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
Brain injury
2,011
Many-electron dynamics of a Xe atom in strong and superstrong laser fields.
We report on detailed investigations of ionization dynamics of a Xe atom exposed to intense 800-nm pulses of 20-fs duration in the extensive intensity range from 10(13)-10(18) W/cm(2). Ion yields of Xe+-Xe20+ were observed as a function of laser intensity and compared with the results from a single active electron base...
10.1103/PhysRevLett.92.123001
15,089,668
Physical review letters
2,004
Rapid Determination of L-carnitine in Infant and Toddler Formulas by Liquid Chromatography Tandem Mass Spectrometry.
A rapid and simple analytical method for L-carnitine was developed for infant and toddler formulas by liquid chromatography tandem mass spectrometry (LC-MS/MS). A 0.3 g of infant formula and toddler formula sample was mixed in a 50 mL conical tube with 9 mL water and 1 mL 0.1 M hydrochloric acid (HCl) to chemical extra...
10.5851/kosfa.2014.34.6.749
26,761,670
Korean journal for food science of animal resources
2,014
Antimicrobial activity of ceftaroline and other anti-infective agents against microbial pathogens recovered from the surgical intensive care patient population: a prevalence analysis.
BACKGROUND Ceftaroline is a new parenteral cephalosporin agent with excellent activity against methicillin-sensitive (MSSA) and resistant strains of Staphylococcus aureus (MRSA). Critically ill surgical patients are susceptible to infection, often by multi-drug-resistant pathogens. The activity of ceftaroline against s...
10.1089/sur.2013.172
24,896,013
D000890:Anti-Infective Agents; D001419:Bacteria; D001424:Bacterial Infections; D002511:Cephalosporins; D003422:Critical Care; D006801:Humans; D008826:Microbial Sensitivity Tests; D015995:Prevalence; D000097583:Ceftaroline
Surgical infections
2,014
D000890:Anti-Infective Agents; D002511:Cephalosporins
Ethical Concerns in Sport: When the Will to Win Exceed the Spirit of Sport.
Background: The need to advance and achieve success is deeply ingrained in human evolution. As a species, humans developed instincts that allowed them to survive and transmit their genes along generations. The will to win is an instinct that has been maintained in the species for millions of years. Sport is an activity...
10.3390/bs8090078
30,177,618
Behavioral sciences (Basel, Switzerland)
2,018
[Differential hemodynamically oriented therapy in the early hospital phase of acute myocardial infarction].
100 patients with acute myocardial infarction were examined by means of catheterization of the pulmonary artery, dilution of isotopes and phonoelectrocardiography immediately after admission to the clinic and under a therapy following haemodynamic viewpoints within 2-24 hours after the beginning of the treatment, takin...
7,157,891
D000328:Adult; D000368:Aged; D003326:Coronary Circulation; D003937:Diagnosis, Differential; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction; D012769:Shock; D012770:Shock, Cardiogenic
Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete
1,982
Substrate structural requirements of Schizosaccharomyces pombe RNase P.
RNase P from Schizosaccharomyces pombe has been purified over 2000-fold. The apparent Km for two S. pombe tRNA precursors derived from the supS1 and sup3-e tRNA(Ser) genes is 20 nM; the apparent Vmax is 2.5 nM/min (supS1) and 1.1 nM/min (sup3-e). Processing studies with precursors of other mutants show that the structu...
10.1016/0014-5793(89)81433-4
2,666,172
D001483:Base Sequence; D004722:Endoribonucleases; D008969:Molecular Sequence Data; D009154:Mutation; D009690:Nucleic Acid Conformation; D012322:RNA Precursors; D012331:RNA, Fungal; D012362:RNA, Transfer, Ser; D043262:Ribonuclease P; D012441:Saccharomyces cerevisiae; D004718:Saccharomycetales; D012568:Schizosaccharomyce...
FEBS letters
1,989
D012322:RNA Precursors; D012331:RNA, Fungal; D012362:RNA, Transfer, Ser; D004722:Endoribonucleases; D043262:Ribonuclease P
Surgical Management of Pediatric Hidradenitis Suppurativa: A Case Series and Review of the Literature.
BACKGROUND Hidradenitis suppurativa (HS) is a chronic and physically debilitating condition. Achieving long-term remission is difficult and sometimes remains elusive despite use of multiple pharmacological agents. However, surgery remains underused in the pediatric population. METHODS We conducted a retrospective rev...
10.1097/SAP.0000000000002195
31,913,903
D000293:Adolescent; D002648:Child; D015331:Cohort Studies; D005260:Female; D017497:Hidradenitis Suppurativa; D006801:Humans; D012086:Reoperation; D012189:Retrospective Studies
Annals of plastic surgery
2,020
Biomechanical testing of spinal segment fixed by thoracolumbar spine locking plate on the swine lumbar spine.
BACKGROUND The aim of the experiment was to compare the mechanical properties of intact spinal segment with impaired intervertebral disc and impaired intervertebral disc fixed by TSLP (Thoracolumbar Spine Locking Plate). METHODS AND RESULTS Spinal specimens were taken from domestic swine. A total of 8 test mechanical...
10.5507/bp.2010.052
21,293,547
D000818:Animals; D001696:Biomechanical Phenomena; D001860:Bone Plates; D007403:Intervertebral Disc; D008159:Lumbar Vertebrae; D013122:Spinal Diseases; D013904:Thoracic Vertebrae
Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia
2,010
Chemical glycosidation of trypsin with O-carboxymethyl-poly-beta-cyclodextrin: catalytic and stability properties.
The polysaccharide O-carboxymethyl-poly-beta-cyclodextrin was synthesized (molecular mass 13,000 Da, 40% carboxy groups) and attached to the surface of bovine pancreatic trypsin. The resulting neoglycoenzyme retained high proteolytic and esterolytic activity and contained approx. 1.0 mol of polymer/mol of enzyme. The o...
10.1042/BA20040115
15,317,487
D000818:Animals; D002266:Carboxymethylcellulose Sodium; D002384:Catalysis; D002417:Cattle; D004789:Enzyme Activation; D004795:Enzyme Stability; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D046911:Macromolecular Substances; D008970:Molecular Weight; D010179:Pancreas; D011485:Protein Binding; D011489:Protein De...
Biotechnology and applied biochemistry
2,005
D046911:Macromolecular Substances; D047392:beta-Cyclodextrins; D014357:Trypsin; D002266:Carboxymethylcellulose Sodium
A small effect of conservation agriculture on soil biodiversity that differs between biological kingdoms and geographic locations.
Larger easily visible animals and plants are negatively affected by agrochemicals used for intensive food production, but we do not understand the general spatial and temporal effects of agrochemicals on the multitudes of bacteria, fungi, and small invertebrate animals that underpin ecosystem productivity. We sequenced...
10.1016/j.isci.2021.102280
33,817,583
iScience
2,021
Lipoprotein(a), an Opsonin, Enhances the Phagocytosis of Nontypeable Haemophilus influenzae by Macrophages.
We recently showed that both nontypeable Haemophilus influenzae (NTHi) and its surface plasminogen- (Plg-) binding proteins interact with lipoprotein(a) (Lp(a)) in a lysine-dependent manner. Because Lp(a) can be taken up by macrophages, we postulated that it serves as an opsonin to enhance phagocytosis of NTHi by macro...
10.1155/2021/2185568
34,765,679
D018955:CD36 Antigens; D002460:Cell Line; D045744:Cell Line, Tumor; D004926:Escherichia coli; D006192:Haemophilus Infections; D006193:Haemophilus influenzae; D006801:Humans; D007963:Leukocytes, Mononuclear; D017270:Lipoprotein(a); D008264:Macrophages; D009895:Opsonin Proteins; D010587:Phagocytosis; D020298:U937 Cells
Journal of immunology research
2,021
D018955:CD36 Antigens; D017270:Lipoprotein(a); D009895:Opsonin Proteins
Public knowledge and attitudes to AIDS.
Three independent cross-sectional surveys of public knowledge and attitudes about AIDS were conducted on a representative sample of people aged 15-54 resident in Wales. 1,303 were interviewed in their homes in February 1987, 683 in September 1987 and 676 in March 1988. The results show that most people knew that having...
10.1016/s0033-3506(89)80076-9
2,787,032
D000163:Acquired Immunodeficiency Syndrome; D000293:Adolescent; D000328:Adult; D001294:Attitude to Health; D003430:Cross-Sectional Studies; D005260:Female; D006266:Health Education; D006801:Humans; D008297:Male; D008875:Middle Aged; D011639:Public Opinion; D014852:Wales
Public health
1,989
Bone Mineral Density Screening and the Frequency of Osteopenia/Osteoporosis in Turkish Adult Patients With Celiac Disease.
BACKGROUND The aim of this study was to evaluate the prevalence of osteopenia and osteoporosis in adult patients with celiac disease (CD) at diagnosis and/or in the follow-up after a gluten-free diet (GFD). METHODS Adult patients diagnosed with CD were retrospectively screened through follow-up records and computer d...
10.5152/tjg.2021.20313
34,464,324
D015502:Absorptiometry, Photon; D000328:Adult; D015519:Bone Density; D001851:Bone Diseases, Metabolic; D002446:Celiac Disease; D055050:Diet, Gluten-Free; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D010024:Osteoporosis; D015995:Prevalence; D012189:Retrospective Studies; D0...
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology
2,021
Antiviral effects of nisin, lysozyme, lactoferrin and their mixtures against bovine viral diarrhoea virus.
BACKGROUND Bovine viral diarrhoea virus (BVDV), an enveloped, single-stranded, positive-sense RNA virus from the Flaviviridae family, is a globally distributed bovine pathogen. BVDV infection in cattle, despite having a wide range of clinical manifestations, is invariably responsible for significant economic losses. To...
10.1186/s12917-019-2067-6
31,488,163
D000818:Animals; D000998:Antiviral Agents; D002417:Cattle; D002460:Cell Line; D003603:Cytotoxins; D001908:Diarrhea Viruses, Bovine Viral; D007781:Lactoferrin; D009113:Muramidase; D009561:Nisin; D012367:RNA, Viral
BMC veterinary research
2,019
D000998:Antiviral Agents; D003603:Cytotoxins; D012367:RNA, Viral; D009561:Nisin; D009113:Muramidase; D007781:Lactoferrin
Cold temperature stress and damaged skin induced high mortality in barramundi (Lates calcarifer) challenged with Vibrio harveyi.
Most diseases in aquaculture are caused by opportunistic pathogens. One of them, Vibrio harveyi, is a widespread Gram-negative bacterium that has become an important pathogen of aquatic species in marine environments. Here, we propose the use of the causal pie model as a framework to conceptualize the causation of vibr...
10.1111/jfd.13784
36,966,382
D000818:Animals; D003080:Cold Temperature; D013696:Temperature; D058639:Cold-Shock Response; D010865:Pilot Projects; D005393:Fish Diseases; D014733:Vibrio; D010473:Perciformes; D014735:Vibrio Infections; D005399:Fishes
Journal of fish diseases
2,023