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PCI for stable angina: A missed opportunity for shared decision-making. | Percutaneous coronary intervention (PCI) continues to be frequently performed for patients with stable coronary artery disease, despite clear evidence that it provides minimal benefit over optimal medical therapy and entails small but not inconsequential risks. Many patients and doctors do not fully understand the risk... | 10.3949/ccjm.85gr.17004 | 29,425,088 | D060050:Angina, Stable; D003657:Decision Making; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention | Cleveland Clinic journal of medicine | 2,018 | |
General practitioner knowledge of and engagement with telehealth-at-home medical abortion provision. | In Australia, there are many barriers to abortion, particularly for women living in regional, rural and remote areas. Telehealth provision of medical abortion is safe, effective and acceptable to patients and providers. In 2015, Marie Stopes Australia (MSA) launched an at-home telehealth model for medical abortion to w... | 10.1071/PY20297 | 34,782,057 | D001315:Australia; D005260:Female; D058005:General Practitioners; D006801:Humans; D011247:Pregnancy; D017216:Telemedicine; D014195:Travel | Australian journal of primary health | 2,021 | |
Integrative Functional Genomic Analysis in Multiplex Autism Families from Kazakhstan. | The study of extended pedigrees containing autism spectrum disorder- (ASD-) related broader autism phenotypes (BAP) offers a promising approach to the search for ASD candidate variants. Here, a total of 650,000 genetic markers were tested in four Kazakhstani multiplex families with ASD and BAP to obtain data on de novo... | 10.1155/2022/1509994 | 36,199,823 | D017487:Ankyrins; D000067877:Autism Spectrum Disorder; D001321:Autistic Disorder; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D005819:Genetic Markers; D020022:Genetic Predisposition to Disease; D023281:Genomics; D006801:Humans; D007623:Kazakhstan; D019006:Neural Cell Adhesion Molecules | Disease markers | 2,022 | D017487:Ankyrins; D005819:Genetic Markers; D019006:Neural Cell Adhesion Molecules; D019005:Cystic Fibrosis Transmembrane Conductance Regulator |
Explainable Machine Learning-Based Risk Prediction Model for In-Hospital Mortality after Continuous Renal Replacement Therapy Initiation. | In this study, we established an explainable and personalized risk prediction model for in-hospital mortality after continuous renal replacement therapy (CRRT) initiation. This retrospective cohort study was conducted at Changhua Christian Hospital (CCH). A total of 2932 consecutive intensive care unit patients receivi... | 10.3390/diagnostics12061496 | 35,741,306 | Diagnostics (Basel, Switzerland) | 2,022 | ||
Reduced mixing in inertial confinement fusion with early-time interface acceleration. | In inertial confinement fusion (ICF) implosions, the interface between the cryogenic DT fuel and the ablator is unstable to shock acceleration (the Richtmyer-Meshkov instability, RM) and constant acceleration (Rayleigh-Taylor instability, RT). Instability growth at this interface can reduce the final compression, limit... | 10.1103/PhysRevE.108.L023202 | 37,723,759 | Physical review. E | 2,023 | ||
Constitutive and LPS-induced gene expression in a macrophage-like cell line from the rainbow trout (Oncorhynchus mykiss). | The lack of cell lines from mononuclear phagocytes of salmonid fish has impeded the study of immune function at a cellular level in these economically and ecologically important animals. Here, we report on the further characterization of RTS11, a previously described macrophage-like cell line from the rainbow trout spl... | 10.1016/s0145-305x(00)00019-7 | 10,831,791 | D000818:Animals; D002460:Cell Line; D051546:Cyclooxygenase 2; D016207:Cytokines; D005786:Gene Expression Regulation; D000949:Histocompatibility Antigens Class II; D007527:Isoenzymes; D008070:Lipopolysaccharides; D008264:Macrophages; D017686:Oncorhynchus mykiss; D011451:Prostaglandin-Endoperoxide Synthases | Developmental and comparative immunology | 2,000 | D016207:Cytokines; D000949:Histocompatibility Antigens Class II; D007527:Isoenzymes; D008070:Lipopolysaccharides; D051546:Cyclooxygenase 2; D011451:Prostaglandin-Endoperoxide Synthases |
Role of T2 mapping of magnetic resonance imaging in the differentiation of endometrial cancer and benign endometrial lesions | PURPOSE
The T2 mapping of magnetic resonance imaging (MRI) in endometrial cancer (EC), benign endometrial lesions (BELs), and normal endometrium (NE) has rarely been reported. This study aimed to determine the T2 values of MRI in EC, BELs, and NE to investigate whether the T2 values can differentiate them and to assess... | 10.4274/dir.2021.21884 | 36,960,606 | D005260:Female; D006801:Humans; D008875:Middle Aged; D000368:Aged; D016889:Endometrial Neoplasms; D008279:Magnetic Resonance Imaging | Diagnostic and interventional radiology (Ankara, Turkey) | 2,023 | |
Integrating ecosystem services in terrestrial conservation planning. | The purpose of this study is to estimate the benefits of ecosystem services for prioritization of land use conservation and to highlight the importance of ecosystem services by comparison between ecosystem service value and green GDP accounting. Based on land use pattern and benefit transfer method, this research estim... | 10.1007/s11356-017-8795-x | 28,349,311 | D002681:China; D003247:Conservation of Natural Resources; D017753:Ecosystem; D004784:Environmental Monitoring; D040362:Geographic Information Systems; D013624:Taiwan; D053833:Wetlands | Environmental science and pollution research international | 2,017 | |
Incipient cognition solves the spatial reciprocity conundrum of cooperation. | BACKGROUND
From the simplest living organisms to human societies, cooperation among individuals emerges as a paradox difficult to explain and describe mathematically, although very often observed in reality. Evolutionary game theory offers an excellent toolbar to investigate this issue. Spatial structure has been one o... | 10.1371/journal.pone.0017939 | 21,423,580 | D003071:Cognition; D003299:Cooperative Behavior; D005716:Game Theory; D006801:Humans; D007398:Interpersonal Relations; D008960:Models, Psychological | PloS one | 2,011 | |
Stem cell factor improves the repopulating ability of primitive hematopoietic stem cells after sublethal irradiation (and, to a lesser extent) after bone marrow transplantation in mice. | Bone marrow transplantation (BMT) and sublethal irradiation (XRT) cause profound long-term damage to hematopoietic stem cells. We used the competitive repopulation assay in mice to test the ability of granulocyte-macrophage colony-stimulating factor (GM-CSF) and stem cell factor (SCF), cytokines given in clinical setti... | 10.1002/stem.160112 | 9,554,035 | D000818:Animals; D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation; D002452:Cell Count; D006412:Hematopoietic Stem Cells; D051379:Mice; D008810:Mice, Inbred C57BL; D019089:Stem Cell Factor; D013997:Time Factors | Stem cells (Dayton, Ohio) | 1,998 | D019089:Stem Cell Factor |
Studies on phytotoxic effect of aluminium on growth and some morphological parameters of Vigna radiata L. Wilczek. | Aluminium toxicity is a major deterrent for plant growth in acid soils below pH 5.0. This study deals with effect of aluminium toxicity on growth of mungbean (Vigna radiata L. Wilczek) seedlings. Seed germination (in %) declined with increased content of Al2(SO4)3, while promotive effect was observed at very low dosage... | 12,674,383 | D000535:Aluminum; D004305:Dose-Response Relationship, Drug; D007887:Fabaceae; D006863:Hydrogen-Ion Concentration; D008854:Microscopy, Electron; D018515:Plant Leaves; D036226:Seedlings; D012989:Soil Pollutants | Journal of environmental biology | 2,002 | D012989:Soil Pollutants; D000535:Aluminum | |
Somatostatin-like immunoreactivity in a subpopulation of nerve terminals in frog sympathetic ganglia. | A somatostatin-like substance was observed specifically in a subset of B-type nerve terminals in frog paravertebral ganglia. The middle ganglia (4th and 5th) of the sympathetic chain contained the highest proportions of somatostatin-positive terminals, with decreasing proportions in more caudal or rostral ganglia. Intr... | 10.1016/0165-1838(88)90074-4 | 2,902,119 | D000818:Animals; D004594:Electrophysiology; D005260:Female; D005728:Ganglia, Sympathetic; D007150:Immunohistochemistry; D008297:Male; D009411:Nerve Endings; D011892:Rana catesbeiana; D013004:Somatostatin | Journal of the autonomic nervous system | 1,988 | D013004:Somatostatin |
Novel hydrogels of chitosan and poly(vinyl alcohol)-g-glycolic acid copolymer with enhanced rheological properties. | Poly(vinyl alcohol) (PVA) has been grafted with glycolic acid (GL), a biodegradable hydroxyl acid to yield modified poly(vinyl alcohol) (PVAGL). The formation of hydrogels at pH = 6.8 and physiological temperature through blending chitosan (CS) and PVAGL at different concentrations has been investigated. FTIR, DOSY NMR... | 24,528,729 | D048271:Chitosan; D006016:Glycolates; D020100:Hydrogels; D011142:Polyvinyl Alcohol; D012212:Rheology | Carbohydrate polymers | 2,014 | D006016:Glycolates; D020100:Hydrogels; C031149:glycolic acid; D011142:Polyvinyl Alcohol; D048271:Chitosan | |
First report on DNA content of three species of Amorphophallus. | The Amorphophallus genus is a perennial herb which belongs to the family Araceae. There are more than 170 species in this genus, which is widely distributed in tropical and subtropical areas. As a kind of food and medicine Amorphophallus has been used for more than 2000 years in China. Because of the high content of ko... | 32,482,925 | D031056:Amorphophallus; D002681:China; D004247:DNA; D005434:Flow Cytometry; D059646:Genome Size; D018745:Genome, Plant; D007214:Indonesia; D011003:Ploidies | Journal of genetics | 2,020 | D004247:DNA | |
Atomic structure and dynamics of pentameric ligand-gated ion channels: new insight from bacterial homologues. | Pentameric ligand-gated ion channels (pLGICs) are widely expressed in the animal kingdom and are key players of neurotransmission by acetylcholine (ACh), gamma-amminobutyric acid (GABA), glycine and serotonin. It is now established that this family has a prokaryotic origin, since more than 20 homologues have been disco... | 10.1113/jphysiol.2009.183160 | 19,995,852 | D000595:Amino Acid Sequence; D001426:Bacterial Proteins; D018360:Crystallography, X-Ray; D015640:Ion Channel Gating; D007473:Ion Channels; D008969:Molecular Sequence Data; D020836:Protein Structure, Quaternary; D017434:Protein Structure, Tertiary; D017981:Receptors, Neurotransmitter | The Journal of physiology | 2,010 | D001426:Bacterial Proteins; D007473:Ion Channels; D017981:Receptors, Neurotransmitter |
Collection reform: build stronger relationships with self-pay patients. | New approaches and technologies are changing the collections process to make it work better for both self-pay patients and hospitals, including: Upfront identification of patients eligible for financial assistance. Access to real-time financial information. Automated matching of financial need and available assistance ... | 16,184,964 | D000067:Accounts Payable and Receivable; D004469:Economics, Hospital; D005382:Financing, Personal; D006739:Hospital Administration; D017060:Patient Satisfaction; D014481:United States | Healthcare financial management : journal of the Healthcare Financial Management Association | 2,005 | ||
Suicidal behaviours among in-school adolescents in Mozambique: Cross-sectional evidence of the prevalence and predictors using the Global School-Based Health Survey data. | INTRODUCTION
Despite interventions by low and middle-income countries toward the achievement of the global Sustainable Development Goal (SDG) on promoting mental health and well-being of their populace by the year 2030, suicidal behaviours continue to be major causes of premature mortality, especially among young peopl... | 10.1371/journal.pone.0236448 | 32,706,805 | D000293:Adolescent; D000294:Adolescent Behavior; D001007:Anxiety; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006306:Health Surveys; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D009073:Mozambique; D000066550:Physical Abuse; D015995:Prevalence; D012307:Risk Factors; D013334:Studen... | PloS one | 2,020 | |
Dataset on the mass spectrometry-based proteomic profiling of mouse embryonic fibroblasts from a wild type and DYT-TOR1A mouse model of dystonia, basally and during stress. | Here, we present quantitative subcellular compartment-specific proteomic data from wildtype and DYT-TOR1A heterozygous mouse embryonic fibroblasts (MEFs) basally and following thapsigargin (Tg) treatment [1]. In this experiment, we generated MEFs from wild type (WT) and a heterozygous DYT-TOR1A mouse model of dystonia.... | 10.1016/j.dib.2021.107609 | 34,901,342 | Data in brief | 2,021 | ||
A Matching-Adjusted Indirect Comparison of Single-Arm Trials in Patients with Relapsed or Refractory Follicular Lymphoma Who Received at Least Two Prior Systemic Treatments: Tazemetostat was Associated with a Lower Risk for Safety Outcomes Versus the PI3-Kinase Inhibitors Idelalisib, Duvelisib, Copanlisib, and Umbralis... | INTRODUCTION
Tazemetostat is an enhancer of zeste homolog 2 (EZH2) inhibitor recommended for patients with relapsed/refractory (R/R) follicular lymphoma (FL) after demonstrating single-agent, antitumor activity in patients with wild-type or mutant EZH2. The phosphoinositide 3-kinase (PI3K) inhibitors idelalisib, copanl... | 10.1007/s12325-022-02054-z | 35,157,216 | D001549:Benzamides; D001713:Biphenyl Compounds; D002675:Child, Preschool; D006576:Heterocyclic Compounds, 4 or More Rings; D006801:Humans; D007546:Isoquinolines; D008224:Lymphoma, Follicular; D009025:Morpholines; D009364:Neoplasm Recurrence, Local; D019869:Phosphatidylinositol 3-Kinases; D011687:Purines; D011728:Pyrido... | Advances in therapy | 2,022 | D001549:Benzamides; D001713:Biphenyl Compounds; D006576:Heterocyclic Compounds, 4 or More Rings; D007546:Isoquinolines; D009025:Morpholines; D011687:Purines; D011728:Pyridones; D011743:Pyrimidines; D011799:Quinazolines; D052999:Quinazolinones; C000626319:umbralisib; C586691:duvelisib; C000593333:tazemetostat; C00058925... |
Practical and General Alcohol Deoxygenation Protocol. | Herein, we describe a practical protocol for the removal of alcohol functional groups through reductive cleavage of their benzoate ester analogs. This transformation requires a strong single electron transfer (SET) reductant and a means to accelerate slow fragmentation following substrate reduction. To accomplish this,... | 10.1002/anie.202300178 | 36,840,940 | Angewandte Chemie (International ed. in English) | 2,023 | ||
Two-component transdental implants. | Transdental implantation is a procedure of tooth stabilization in maxillary and/or mandibular bone. Indications for use of these implants are root fractures, chronic periapical inflammations and periodontal disease. Transdental implants have been used in the Clinic for Maxillofacial Surgery since 1977. In the period of... | 9,354,134 | D003757:Dental Implantation; D015921:Dental Implants; D006801:Humans | Vojnosanitetski pregled | 1,997 | D015921:Dental Implants | |
A contribution to genetic etiology of complex regional pain syndrome type I (algodystropy syndrome) based on quantitative analysis of digitopalmar dermatoglyphics in sixty men. | The patterns of the ridges of the skin of the fingers and palms were determined in sixty men with complex regional pain syndrome (type I) as a measure of disease prevention. The study included 25 dermatoglyphic traits: number of epidermal ridges on all ten fingers; their sum for five and ten fingers; four traits on bot... | 16,689,105 | D003878:Dermatoglyphics; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D012019:Reflex Sympathetic Dystrophy | Reumatizam | 2,005 | ||
[Indigenous medicine in Spain and its commercialization (1492-1550)]. | In this article the important herbalist knowledge that the native healers or behiques possessed in la Española are pointed out. They concealed their herbalist knowledge as a means to preserve their priviledged social status, on the ather haud, es a rejection to the conquerors. Soon the spaniards realised the importance... | 11,636,888 | D000434:Alcoholic Beverages; D000569:Americas; D018595:Colonialism; D003132:Commerce; D049668:History, 15th Century; D049669:History, 16th Century; D006801:Humans; D008517:Phytotherapy; D010946:Plants, Medicinal; D011174:Portugal; D013030:Spain | Asclepio; archivo iberoamericano de historia de la medicina y antropologia medica | 1,997 | ||
Osteosarcoma inheritance in two families of Scottish deerhounds. | BACKGROUND
Osteosarcoma is the most common neoplastic disease in Scottish Deerhounds. For Deerhounds, a 2007 population-based study concluded that a single dominant genetic factor largely governed disease risk. For Greyhounds, Rottweilers, and Irish Wolfhounds, a 2013 genome-wide association study found multiple geneti... | 10.1186/s40575-017-0042-8 | 28,331,626 | Canine genetics and epidemiology | 2,017 | ||
Complementary and alternative medicine for children with sickle cell disease: A systematic review. | BACKGROUND
Complementary and alternative medicine (CAM) is a popular alternative to opioid and other analgesics in sickle cell disease (SCD). We review the effectiveness, prevalence, and factors associated with CAM use in the pediatric SCD population.
METHODS
The review protocol was created based on Preferred Reporti... | 10.1016/j.blre.2023.101052 | 36,775,794 | D002648:Child; D006801:Humans; D000529:Complementary Therapies; D010146:Pain; D000755:Anemia, Sickle Cell | Blood reviews | 2,023 | |
Total Serum Cholesterol and Pancreatic Cancer: A Nested Case-Control Study. | BACKGROUND
Pancreatic cancer is the third leading cause of cancer-related death in the United States. Total serum cholesterol (TSC) may predict cancer risk, although its role independent of statins remains elusive. We examined the association between TSC and pancreatic cancer risk independent of statins.
METHODS
A ne... | 10.1158/1055-9965.EPI-18-0421 | 30,333,217 | D000368:Aged; D016022:Case-Control Studies; D002784:Cholesterol; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms; D012307:Risk Factors; D006113:United Kingdom | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology | 2,019 | D002784:Cholesterol |
Personalized Management Strategies in Mast Cell Disorders: ECNM-AIM User's Guide for Daily Clinical Practice. | Mastocytosis is a myeloid neoplasm defined by expansion and focal accumulation of clonal mast cells (MCs) in one or more organs. The disease exhibits a complex pathology and may be complicated by MC activation, bone abnormalities, neurological problems, gastrointestinal symptoms, and/or hematologic progression. The Wor... | 10.1016/j.jaip.2022.03.007 | 35,342,031 | D006801:Humans; D007073:Immunoglobulin E; D008407:Mast Cells; D008415:Mastocytosis; D034721:Mastocytosis, Systemic; D019009:Proto-Oncogene Proteins c-kit; D053802:Tryptases | The journal of allergy and clinical immunology. In practice | 2,022 | D007073:Immunoglobulin E; D019009:Proto-Oncogene Proteins c-kit; D053802:Tryptases |
Psychometric investigation of a belief system: caregiving to the chronically ill parent. | This research draws on psychometric theory to assess open-ended items and develop reliable measures for investigation of caregiver ideology. Coding criteria used in a qualitative investigation of caregivers' beliefs about filial obligation and parental dependency were transformed into closed-end items and fielded with ... | 10.1016/0277-9536(92)90008-e | 1,439,920 | D000368:Aged; D000369:Aged, 80 and over; D017028:Caregivers; D002908:Chronic Disease; D005163:Factor Analysis, Statistical; D005190:Family; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010549:Personal Satisfaction; D011594:Psychometrics; D012941:Social Responsibility; D012945:Social Values | Social science & medicine (1982) | 1,992 | |
Effects of a combined lifestyle score on 10-year mortality in Korean men and women: a prospective cohort study. | BACKGROUND
Most studies that have evaluated the association between combined lifestyle factors and mortality outcomes have been conducted in populations of Caucasian origin. The objective of this study was to examine the association between combined lifestyle scores and the risk of mortality in Korean men and women.
... | 10.1186/1471-2458-12-673 | 22,900,981 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009026:Mortality; D016016:Proportional Hazards Models; D011446:Prospective Studies; D056910:Republic of Korea; D018570:Risk Assessment; D012309:Risk-Ta... | BMC public health | 2,012 | |
Lipases from different sources vary widely in dependence of catalytic activity on water activity. | We have measured the rates of esterification in hexane catalysed by suspended immobilised lipases (triacylglycerol acylhydrolase, EC 3.1.1.3), with pre-equilibration to known thermodynamic water activity (a(w)). There were important differences between the enzymes from five different microbes in their retention of acti... | 10.1016/0167-4838(92)90316-6 | 1,643,087 | D000327:Adsorption; D000595:Amino Acid Sequence; D002175:Candida; D002384:Catalysis; D004951:Esterification; D008049:Lipase; D008969:Molecular Sequence Data; D011549:Pseudomonas; D012233:Rhizopus; D013329:Structure-Activity Relationship; D014867:Water | Biochimica et biophysica acta | 1,992 | D014867:Water; D008049:Lipase |
An open trial of topical tacrolimus for erosive oral lichen planus. | Erosive oral lichen planus is a chronic, painful disease that is frequently refractory to treatment. We describe 6 patients with erosive oral lichen planus, not responsive to topical steroids, who showed substantial improvement with the use of topical tacrolimus ointment 0.1%. This medication was well tolerated and app... | 10.1067/mjd.2002.126275 | 12,271,312 | D000287:Administration, Topical; D000328:Adult; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents; D017676:Lichen Planus, Oral; D008297:Male; D016559:Tacrolimus; D016896:Treatment Outcome | Journal of the American Academy of Dermatology | 2,002 | D007166:Immunosuppressive Agents; D016559:Tacrolimus |
Distribution of different phosphorylated forms of RNA polymerase II in relation to Cajal and PML bodies in human cells: an ultrastructural study. | The mammalian nucleus is a highly organised organelle that contains many subcompartments with roles in DNA replication and repair, gene expression and RNA processing. Cajal and promyelocytic leukaemia (PML) bodies are discrete nuclear structures with specific molecular signatures. RNA polymerase II and many transcripti... | 10.1007/s00418-005-0064-2 | 16,187,066 | D000906:Antibodies; D020541:Coiled Bodies; D005455:Fluorescent Antibody Technique; D006367:HeLa Cells; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007150:Immunohistochemistry; D015473:Leukemia, Promyelocytic, Acute; D018613:Microscopy, Confocal; D008854:Microscopy, Electron; D010766:Phosphorylation; D... | Histochemistry and cell biology | 2,006 | D000906:Antibodies; D012334:RNA, Neoplasm; C018009:5-bromouridine triphosphate; D012319:RNA Polymerase II; D014544:Uridine Triphosphate |
[Damage control laparotomy in blunt abdominal injury]. | PURPOSE OF THE STUDY
Damage control surgery is one of the major advances in surgical techniques used in polytrauma patients in the past 25 years. It is based on a foreshortened pre-operative examination during ongoing resuscitation which includes surgical intervention in an injured patient with severe hypotension due t... | 19,755,055 | D000007:Abdominal Injuries; D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007813:Laparotomy; D008297:Male; D008875:Middle Aged; D014949:Wounds, Nonpenetrating; D055815:Young Adult | Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca | 2,009 | ||
Functional expression of receptors for calcitonin gene-related peptide, calcitonin, and vasoactive intestinal peptide in the human thymus and thymomas from myasthenia gravis patients. | The molecular and functional expression of serpentine membrane receptors for vasoactive intestinal peptide (VIP), calcitonin gene-related peptide (CGRP), and calcitonin (CT) were characterized in human thymus and thymomas from myasthenia gravis (MG) patients and thymic epithelial cells either in primary culture (PTEC) ... | 9,973,484 | D000293:Adolescent; D000328:Adult; D000957:Antigens, Viral, Tumor; D015139:Blotting, Southern; D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide; D018929:Cell Culture Techniques; D002461:Cell Line, Transformed; D002472:Cell Transformation, Viral; D002648:Child; D002675:Child, Preschool; D004847:Epithelial Cel... | Journal of immunology (Baltimore, Md. : 1950) | 1,999 | D000957:Antigens, Viral, Tumor; D018003:Receptors, Calcitonin; D018015:Receptors, Calcitonin Gene-Related Peptide; D011950:Receptors, Cholinergic; D018013:Receptors, Neuropeptide; D018005:Receptors, Vasoactive Intestinal Peptide; D014660:Vasoactive Intestinal Peptide; D002116:Calcitonin; D015740:Calcitonin Gene-Related... | |
Ultrafast Nanocrystalline-TiO2 (B)/Carbon Nanotube Hyperdispersion Prepared via Combined Ultracentrifugation and Hydrothermal Treatments for Hybrid Supercapacitors. | Anisotropically grown (b-axis short) single-nano TiO2 (B), uniformly hyper-dispersed on the surface of multiwalled carbon nanotubes (MWCNT), was successfully synthesized via an in situ ultracentrifugation (UC) process coupled with a follow-up hydrothermal treatment. The uc-TiO2 (B)/MWCNT composite materials enable ultr... | 10.1002/adma.201600798 | 27,229,372 | Advanced materials (Deerfield Beach, Fla.) | 2,016 | ||
Brain morphology of Gymnura lessae and Gymnura marmorata (Chondrichthyes: Gymnuridae) and its implications for batoid brain evolution. | Although skeletal and muscle anatomy has supported Gymnuridae as the sister group of the most derived myliobatoids, recent studies based on molecular characters suggest that the family branches into a more basal position than previously thought. This study aims to understand the brain anatomy of the genus Gymnura and i... | 10.1002/ar.24528 | 33,029,915 | D000818:Animals; D005075:Biological Evolution; D001921:Brain; D018940:Elasmobranchii; D010802:Phylogeny | Anatomical record (Hoboken, N.J. : 2007) | 2,021 | |
Assessing flavivirus, lentivirus, and herpesvirus exposure in free-ranging ring-tailed lemurs in southwestern Madagascar. | The ring-tailed lemur (Lemur catta) is an endangered species found in southwestern Madagascar, and understanding infectious disease susceptibility is an essential step towards the preservation of wild and captive lemur populations. Lemurs are primates that are widely dispersed throughout the island of Madagascar and ma... | 10.7589/0090-3558-43.1.40 | 17,347,392 | D000818:Animals; D000835:Animals, Wild; D000914:Antibodies, Viral; D003247:Conservation of Natural Resources; D005416:Flavivirus; D006564:Herpesviridae; D007900:Lemur; D016086:Lentivirus; D008270:Madagascar; D016036:Seroepidemiologic Studies; D016097:Simian Acquired Immunodeficiency Syndrome; D015302:Simian Immunodefic... | Journal of wildlife diseases | 2,007 | D000914:Antibodies, Viral |
Zoledronate stimulates gamma delta T cells in prostate cancer patients. | Androgen deprivation therapy is the mainstay of treatment for prostate cancer. Given its frequent failure, new therapy that reduces prostate cancer progression would be a breakthrough in treating this disease. Bisphosphonates are well-established agents for treating skeletal-related events (SREs) in prostate cancer pat... | 10.3727/096504010x12671222663638 | 20,681,408 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D005260:Female; D006801:Humans; D007093:Imidazoles; D007167:Immunotherapy; D007376:Interleukin-2; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen;... | Oncology research | 2,010 | D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D007093:Imidazoles; D007376:Interleukin-2; D016692:Receptors, Antigen, T-Cell, gamma-delta; D000077211:Zoledronic Acid; D017430:Prostate-Specific Antigen |
Low-Grade Albuminuria Is Associated with Left Ventricular Hypertrophy and Diastolic Dysfunction in Patients with Hypertension. | INTRODUCTION
Microalbuminuria is a risk factor for cardiovascular morbidity and mortality in hypertensive patients. However, the relationship between low-grade albuminuria, a higher level of albuminuria below microalbuminuria threshold, and hypertension-related organ damage is unclear. Left ventricular (LV) hypertrophy... | 10.1159/000500782 | 31,387,099 | D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000419:Albuminuria; D003430:Cross-Sectional Studies; D003971:Diastole; D005260:Female; D006801:Humans; D006973:Hypertension; D017379:Hypertrophy, Left Ventricular; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012737:Sex ... | Kidney & blood pressure research | 2,019 | |
An electrochemical aptasensor for thrombin using synergetic catalysis of enzyme and porous Au@Pd core-shell nanostructures for signal amplification. | In this work, a sensitive electrochemical aptasensor for thrombin (TB) based on synergetic catalysis of enzyme and porous Au@Pd core-shell nanostructure has been constructed. With the advantages of large surface area and outstanding catalytic performance, porous Au@Pd core-shell nanostructures were firstly employed as ... | 25,280,342 | D052157:Aptamers, Nucleotide; D015374:Biosensing Techniques; D002384:Catalysis; D003217:Conductometry; D004800:Enzymes, Immobilized; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005949:Glucose Oxidase; D006046:Gold; D053768:Metal Nanoparticles; D058608:Nanopores; D010165:Palladium; D013917:Thrombin | Biosensors & bioelectronics | 2,015 | D052157:Aptamers, Nucleotide; D004800:Enzymes, Immobilized; D010165:Palladium; D006046:Gold; D005949:Glucose Oxidase; D013917:Thrombin | |
Computational drug discovery. | Computational drug discovery is an effective strategy for accelerating and economizing drug discovery and development process. Because of the dramatic increase in the availability of biological macromolecule and small molecule information, the applicability of computational drug discovery has been extended and broadly ... | 10.1038/aps.2012.109 | 22,922,346 | D000818:Animals; D019295:Computational Biology; D017076:Computer-Aided Design; D015195:Drug Design; D055808:Drug Discovery; D006801:Humans; D008958:Models, Molecular; D062105:Molecular Docking Simulation | Acta pharmacologica Sinica | 2,012 | |
Analysis of the phage sequence space: the benefit of structured information. | Phages are the most abundant biological entities on Earth and are central players in the evolution of their bacterial hosts and the emergence of new pathogens. In addition, they bear an enormous potential for the development of new drugs, therapies or nanotechnologies. As a result, interest in phages is reviving. In th... | 10.1016/j.virol.2007.03.047 | 17,482,656 | D001419:Bacteria; D001435:Bacteriophages; D019295:Computational Biology; D016679:Genome, Viral | Virology | 2,007 | |
Physiological roles of adenosine derivatives which are released during neurotransmission in mammalian brain. | 1. Experiments using synaptosome beds suggested that ATP was released from presynaptic sites and degraded to adenosine in the synaptic cleft and that the resulting adenosine was taken up again into nerve endings where it was re-phosphorylated to ATP. 2. Adenosine derivatives in the synaptic cleft inhibited the postsyna... | 217,994 | D000227:Adenine Nucleotides; D000241:Adenosine; D000818:Animals; D001692:Biological Transport; D001921:Brain; D002118:Calcium; D000242:Cyclic AMP; D008564:Membrane Potentials; D009457:Neuroglia; D009474:Neurons; D009830:Olfactory Bulb; D010766:Phosphorylation; D011953:Receptors, Cyclic AMP; D017981:Receptors, Neurotran... | Journal de physiologie | 1,978 | D000227:Adenine Nucleotides; D011953:Receptors, Cyclic AMP; D017981:Receptors, Neurotransmitter; D000242:Cyclic AMP; D000241:Adenosine; D002118:Calcium | |
Body height, mobility, and risk of first and recurrent venous thrombosis. | BACKGROUND
Tall people have an increased risk of a first venous thrombosis. Sedentary lifestyle has been shown to act synergistically with body height, especially during long-haul flights.
OBJECTIVE
To estimate the relation between height and risk of a first and recurrent venous thrombosis and a possible additional a... | 10.1111/jth.12860 | 25,627,967 | D000328:Adult; D000368:Aged; D001827:Body Height; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D009426:Netherlands; D016017:Odds Ratio; D016016:Proportional Hazards Models; D012008:Recurrence; D012307:Risk Factors; D057185:Sedentary Behavior; D... | Journal of thrombosis and haemostasis : JTH | 2,015 | |
[The development of research on the effect of tobacco consumption on the visual organ over the last 200 years]. | The purpose of the paper is to assess the development of research in the area of tobacco-related ocular diseases during the last 200 years. Although the first papers about the toxic effect of tobacco on the eye appeared in the beginnings of the XVIIth century, the real interest in this issue arose in the second half of... | 16,521,981 | D000550:Amblyopia; D002386:Cataract; D005901:Glaucoma; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D012106:Research; D012107:Research Design; D013997:Time Factors; D014029:Tobacco Use Disorder; D014786:Vision Disorders | Przeglad lekarski | 2,005 | ||
Transdifferentiation of neoplastic cells. | Transdifferentiation is a process in which a stable cell's phenotype changes to that of a distinctly different cell type. It occurs during certain physiological processes and leads to transition of tumor cell phenotypes. The latter process includes neoplastic epithelial-epithelial transition, neoplastic epithelial-mese... | 10.1054/mehy.2001.1435 | 11,735,329 | D000818:Animals; D002454:Cell Differentiation; D002471:Cell Transformation, Neoplastic; D006801:Humans; D009369:Neoplasms; D010641:Phenotype | Medical hypotheses | 2,001 | |
Serum C-reactive protein (CRP) as a simple and independent prognostic factor in extranodal natural killer/T-cell lymphoma, nasal type. | BACKGROUND
C-reactive protein (CRP) is a biomarker of the inflammatory response, and it shows significant prognostic value for several types of solid tumors. The prognostic significance of CRP for lymphoma has not been fully examined. We evaluated the prognostic role of baseline serum CRP levels in patients with extran... | 10.1371/journal.pone.0064158 | 23,724,031 | D000293:Adolescent; D000328:Adult; D000368:Aged; D002097:C-Reactive Protein; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D054391:Lymphoma, Extranodal NK-T-Cell; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D056910:Republic of Korea; D012307:Risk Factors; D01601... | PloS one | 2,013 | D002097:C-Reactive Protein |
Sex Differences in Rhythmic Preferences in the Budgerigar (Melopsittacus undulatus): A Comparative Study with Humans. | A variety of parrot species have recently gained attention as members of a small group of non-human animals that are capable of coordinating their movements in time with a rhythmic pulse. This capacity is highly developed in humans, who display unparalleled sensitivity to musical beats and appear to prefer rhythmically... | 10.3389/fpsyg.2016.01543 | 27,757,099 | Frontiers in psychology | 2,016 | ||
Parental participation in the habilitation process--evaluation from a user perspective. | AIM
To develop a national instrument for evaluation of parental participation: (1) to obtain a functional measure of quality from a user perspective; (2) as part of quality development in child habilitation services departments; (3) to create common grounds for the evaluation of important aspects of the habilitation pr... | 10.1046/j.1365-2214.2002.00298.x | 12,568,475 | D000293:Adolescent; D002648:Child; D002662:Child Health Services; D019988:Disabled Children; D005260:Female; D006801:Humans; D008297:Male; D010290:Parents; D015397:Program Evaluation; D011787:Quality of Health Care; D011795:Surveys and Questionnaires | Child: care, health and development | 2,002 | |
Intragenic suppressors that restore the splicing and homing activities of the protein encoded by the second intron of the Saccharomyces capensis cyt b gene. | The second (bi2) intron of the mitochondrial cyt b gene from Saccharomyces capensis encodes a bifunctional protein which acts both as a maturase, promoting intron splicing, and as a homing-endonuclease, I-ScaI, promoting intron mobility. In this work we isolated and characterized revertants from a respiratory-deficient... | 10.1007/s002940000159 | 11,191,212 | D003573:Cytochrome b Group; D014644:Genetic Variation; D007438:Introns; D016296:Mutagenesis; D016297:Mutagenesis, Site-Directed; D016366:Open Reading Frames; D012313:RNA; D012326:RNA Splicing; D012331:RNA, Fungal; D000077278:RNA, Mitochondrial; D012194:RNA-Directed DNA Polymerase; D012440:Saccharomyces; D029701:Sacchar... | Current genetics | 2,000 | D003573:Cytochrome b Group; D012331:RNA, Fungal; D000077278:RNA, Mitochondrial; D029701:Saccharomyces cerevisiae Proteins; D012313:RNA; C066564:aI2 protein, S cerevisiae; D012194:RNA-Directed DNA Polymerase |
Management of bladder cancer. | Bladder cancer is the fourth most common cancer in men and is increasing in incidence in women as well. Bladder cancer has a broad range of behavior and presentations, with different prognoses and treatments. Laboratory research has made strides in elucidating pathways of this cancer, and identifying novel therapeutic ... | 18,923,362 | D001500:BCG Vaccine; D002278:Carcinoma in Situ; D002291:Carcinoma, Papillary; D017024:Chemotherapy, Adjuvant; D015653:Cystectomy; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D015201:Meta-Analysis as Topic; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D012307:Risk Factors; D016... | Minerva urologica e nefrologica = The Italian journal of urology and nephrology | 2,008 | D001500:BCG Vaccine | |
Extrahepatic morbidity and mortality of chronic hepatitis C. | Chronic hepatitis C virus (HCV) infection is associated with several extrahepatic manifestations. Patients with HCV may develop mixed cryoglobulinemia and its sequelae, ranging from cutaneous and visceral vasculitis to glomerulonephritis and B-cell non-Hodgkin lymphoma. HCV-infected patients have increased rates of ins... | 26,319,013 | D000998:Antiviral Agents; D003449:Cryoglobulinemia; D005921:Glomerulonephritis; D044882:Glucose Metabolism Disorders; D016174:Hepacivirus; D019698:Hepatitis C, Chronic; D006801:Humans; D016898:Interferon-alpha; D008223:Lymphoma; D009017:Morbidity; D012254:Ribavirin; D014657:Vasculitis | Gastroenterology | 2,015 | D000998:Antiviral Agents; D016898:Interferon-alpha; D012254:Ribavirin | |
Adsorption of the Cationic Dye Methylene Blue on Anodic Porous Alumina in Sodium Dodecyl Sulfate Solutions. | Dyeing of anodic porous alumina (APA) prepared by aluminum anodization is generally achieved by dipping the positively charged APA surface into a negatively charged dye solution. We have proposed a new method to adsorb dyes and molecules onto APA using negatively charged sodium dodecyl sulfate (SDS). In this study, we ... | 10.1021/acs.langmuir.0c00182 | 32,320,252 | Langmuir : the ACS journal of surfaces and colloids | 2,020 | ||
A case report on spontaneous hemoperitoneum in COVID-19 patient. | INTRODUCTION
Coronavirus disease (COVID-19) is a global a pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Patients commonly present with respiratory tract symptoms and fever. However two third are asymptomatic and unusual presentation is evolving. This has cause management dilemma among... | 10.1016/j.ijscr.2020.09.078 | 32,959,008 | International journal of surgery case reports | 2,020 | ||
Effect of Acupuncture on Functional Capacity and Health-Related Quality of Life of Hemodialysis Patients: Study Protocol for a Randomized Controlled Trial. | The proposed randomized controlled trial protocol will evaluate the effect of acupuncture treatment on the functional capacity (FC) and health-related quality of life (HRQOL) in chronic kidney disease (CKD) with glomerular filtration rate (GFR) category 5 (CKG G5) patients receiving maintenance dialysis. Patients under... | 10.3390/healthcare10102050 | 36,292,497 | Healthcare (Basel, Switzerland) | 2,022 | ||
Amphiregulin as monitoring biomarker for life-threatening acute graft-versushost disease: secondary analysis of two prospective clinical trials. | Not available. | 10.3324/haematol.2023.283215 | 37,706,330 | Haematologica | 2,023 | ||
Prevention of nosocomial pressure ulcers: a process improvement project. | Nosocomial pressure ulcers (PU) occur in approximately 12% of all hospitalized patients. The risk can be determined by a variety of intrinsic and extrinsic factors. As a first line of defense against nosocomial PU, we use the Braden Scale to determine the potential risk of PU development during hospitalization. Once ri... | 10.1097/01.WON.0000281654.40578.88 | 17,667,084 | D003625:Data Collection; D005568:Forms and Records Control; D006760:Hospitalization; D006761:Hospitals; D006801:Humans; D010347:Patient Care Planning; D003668:Pressure Ulcer; D017064:Process Assessment, Health Care; D018570:Risk Assessment | Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society | 2,007 | |
Accelerated Protein Biomarker Discovery from FFPE Tissue Samples Using Single-Shot, Short Gradient Microflow SWATH MS. | We reported and evaluated a microflow, single-shot, short gradient SWATH MS method intended to accelerate the discovery and verification of protein biomarkers in preclassified clinical specimens. The method uses a 15 min gradient microflow-LC peptide separation, an optimized SWATH MS window configuration, and OpenSWATH... | 10.1021/acs.jproteome.9b00671 | 32,053,377 | D015415:Biomarkers; D006801:Humans; D008297:Male; D010455:Peptides; D040901:Proteomics; D012984:Software | Journal of proteome research | 2,020 | D015415:Biomarkers; D010455:Peptides |
Morphological analysis of the upper eyelid tarsus in Asians. | PURPOSE
The present study aims to evaluate morphologic variations of the upper tarsus in Asians.
METHODS
Measurements of superior-inferior and medial-lateral lengths were performed on 54 embalmed cadavers. The superior-inferior length of the tarsus was measured at the central and lateral parts. On the basis of the me... | 10.1097/SAP.0b013e3181e0520d | 21,102,307 | D044466:Asian People; D002102:Cadaver; D002681:China; D005143:Eyelids; D006801:Humans | Annals of plastic surgery | 2,011 | |
Treatment of urinary tract infections. | Urinary tract infections (UTIs) are common conditions in clinical practice. For uncomplicated UTIs, the causative organisms and their antimicrobial susceptibility profiles are generally predictable, and empiric short course (3 day) antibiotic therapy after an abbreviated laboratory workup is advocated. Acute pyelonephr... | 8,588,757 | D000328:Adult; D000900:Anti-Bacterial Agents; D000892:Anti-Infective Agents, Urinary; D002648:Child; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D011704:Pyelonephritis; D012008:Recurrence; D014546:Urinary Catheterization; D014552:Urinary Tract Infections | Australian family physician | 1,995 | D000900:Anti-Bacterial Agents; D000892:Anti-Infective Agents, Urinary | |
Parent perceived quality of life is age-dependent in children with food allergy. | BACKGROUND
Food allergy in children significantly affects their quality of life. Its impact can be analyzed by quality of life questionnaires.
OBJECTIVES
The aim of our study was to validate the French version of disease-specific questionnaires and to evaluate the quality of life in children with IgE-mediated food al... | 10.1111/j.1399-3038.2012.01310.x | 22,554,401 | D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D005512:Food Hypersensitivity; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010290:Parents; D010465:Perception; D011788:Quality of Life; D011795:Surveys and Questionnaires; D013557:S... | Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology | 2,012 | |
[Idiotypic vaccines]. | The paper presents some new informations about anti-idiotypic vaccines. It discusses the advantages and disadvantages of these preparations. | 2,100,818 | D001428:Bacterial Vaccines; D001709:Biotechnology; D006801:Humans; D007130:Immunoglobulin Idiotypes; D009369:Neoplasms; D014765:Viral Vaccines | Przeglad epidemiologiczny | 1,990 | D001428:Bacterial Vaccines; D007130:Immunoglobulin Idiotypes; D014765:Viral Vaccines | |
[Prognosis of children with very low birth weight in the county of Viborg. A follow-up of an unselected patient group]. | Neonatal mortality and follow-up examination among children with birthweight < or = 1500 g born in the period 1983-1987 inclusive has been recorded in an unselected material from a Danish county (Viborg County). There were 100 with birthweight < or = 1500 g and the low-birthweight rate was 7/1000. The neonatal survival... | 7,839,505 | D002648:Child; D002675:Child, Preschool; D003718:Denmark; D006233:Disabled Persons; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007226:Infant Mortality; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008607:Intellectual Disability; D011379:Prognosis; D012189:Retrospective Studies | Ugeskrift for laeger | 1,994 | ||
An LC-MS/MS Method to Measure S-Methyl-l-Cysteine and S-Methyl-l-Cysteine Sulfoxide in Human Specimens Using Isotope Labelled Internal Standards. | This is the first report describing an analytical method for quantitative analysis of two naturally occurring sulphur compounds, S-methyl-l-cysteine (SMC) and S-methyl-l-cysteine sulfoxide (SMCSO), in human body fluids using isotope-labelled internal standards and liquid chromatography-mass spectrometry (LC-MS)/MS tech... | 10.3390/molecules24132427 | 31,269,651 | D000293:Adolescent; D000328:Adult; D000368:Aged; D002853:Chromatography, Liquid; D003545:Cysteine; D005260:Female; D006801:Humans; D007553:Isotope Labeling; D008297:Male; D008875:Middle Aged; D012015:Reference Standards; D015203:Reproducibility of Results; D053719:Tandem Mass Spectrometry; D055815:Young Adult | Molecules (Basel, Switzerland) | 2,019 | C008389:methiin; D003545:Cysteine; C017507:mecysteine |
Catalytic C-H alkynylation of benzylamines and aldehydes with aldimine-directing groups generated in situ. | Iridium-catalysed regioselective C-H alkynylation of unprotected primary benzylamines and aliphatic aldehydes has been achieved using in situ-installed aldimine directing groups. This protocol provides a straightforward route for the synthesis of the alkynylated primary benzylamine and aliphatic aldehyde derivatives, f... | 10.1039/d3cc01414b | 37,139,669 | Chemical communications (Cambridge, England) | 2,023 | ||
Visualised genotyping assay with oral swabs in a closed tube by nested invasive reaction assisted with gold nanoparticle probes. | Single nucleotide polymorphism (SNP) typing is crucial for drug dosage and disease progression. Therefore, a simple and convenient genotyping assay is essential for personalised medicine. Herein, we developed a non-invasive, closed-tube, and visualised method for genotyping. In this method, oral swabs were lysed to dir... | 10.1049/nbt2.12123 | 36,905,169 | D005838:Genotype; D006046:Gold; D065731:Cytochrome P-450 CYP2C19; D053768:Metal Nanoparticles; D016133:Polymerase Chain Reaction | IET nanobiotechnology | 2,023 | D006046:Gold; D065731:Cytochrome P-450 CYP2C19 |
A preliminary report of musculoskeletal dysfunction in female chronic pelvic pain: a blinded study of examination findings. | INTRODUCTION AND HYPOTHESIS
Female chronic pelvic pain is prevalent and causes disability. Can women with self-reported chronic pelvic pain (CPP) be distinguished from pain-free women by demonstrating a greater number of abnormal musculoskeletal findings on examination?
METHODS
In this cross-sectional study, blinded ... | 10.1016/j.jbmt.2011.06.002 | 22,196,427 | D000293:Adolescent; D000328:Adult; D059350:Chronic Pain; D016000:Cluster Analysis; D003430:Cross-Sectional Studies; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D009140:Musculoskeletal Diseases; D017699:Pelvic Pain; D010808:Physical Examination; D010865:Pilot Projects; D057566:S... | Journal of bodywork and movement therapies | 2,012 | |
Considerations of traditional Chinese medicine as adjunct therapy in the management of ulcerative colitis. | Ulcerative colitis (UC) has been treated with traditional Chinese medicine (TCM) for literally thousands of years. This paper gives an overview of TCM in the management of UC, provides an account of the state of the evidence, identifies gaps in the research base, and makes recommendations for future research. TCM is ba... | 10.1007/s12016-012-8328-9 | 22,669,756 | D003093:Colitis, Ulcerative; D018849:Controlled Clinical Trials as Topic; D006801:Humans; D008516:Medicine, Chinese Traditional; D015201:Meta-Analysis as Topic; D017410:Practice Guidelines as Topic | Clinical reviews in allergy & immunology | 2,013 | |
Microspherophakia. | Microspherophakia is present when the crystalline lens is small and relatively spherical with increased antero-posterior thickness. Clinical findings for a patient with idiopathic bilateral microspherophakia are described. The patient was moderately myopic with slightly reduced visual acuity. The anterior chambers (R: ... | 10.1111/j.1444-0938.2002.tb03085.x | 12,366,350 | D000867:Anterior Chamber; D002648:Child; D005190:Family; D005260:Female; D006801:Humans; D007908:Lens, Crystalline; D008499:Medical Records; D009216:Myopia; D014792:Visual Acuity | Clinical & experimental optometry | 2,002 | |
Structural modifications of neuroprotective anti-Parkinsonian (-)-N6-(2-(4-(biphenyl-4-yl)piperazin-1-yl)-ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine (D-264): an effort toward the improvement of in vivo efficacy of the parent molecule. | In our overall goal to develop multifunctional dopamine D2/D3 agonist drugs for the treatment of Parkinson's disease (PD), we previously synthesized potent D3 preferring agonist D-264 (1a), which exhibited neuroprotective properties in two animal models of PD. To enhance the in vivo efficacy of 1a, a structure-activity... | 10.1021/jm401883v | 24,471,976 | D000818:Animals; D052160:Benzothiazoles; D001713:Biphenyl Compounds; D002460:Cell Line; D004195:Disease Models, Animal; D051379:Mice; D018696:Neuroprotective Agents; D010300:Parkinson Disease; D010879:Piperazines; D051381:Rats; D013329:Structure-Activity Relationship; D013844:Thiazoles | Journal of medicinal chemistry | 2,014 | D052160:Benzothiazoles; D001713:Biphenyl Compounds; C529806:N(6)-(2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)-N(6)-propyl-4,5,6,7-tetrahydrobenzo(d)thiazole-2,6-diamine; D018696:Neuroprotective Agents; D010879:Piperazines; D013844:Thiazoles |
Correlation of X-ray vector radiography to bone micro-architecture. | Besides the overall mass density, strength of trabecular bone depends significantly on its microstructure. However, due to dose constraints in medical CT imaging, it is impossible to gain sufficient information about very fine bone structures in vivo on the micrometer scale. Here we show that a recently developed metho... | 10.1038/srep03695 | 24,424,256 | D015519:Bone Density; D005269:Femur; D006801:Humans; D011859:Radiography; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed; D014965:X-Rays | Scientific reports | 2,014 | |
Morphological and Structural Details of Tomato Seed Coat Formation: A Different Functional Role of the Inner and Outer Epidermises in Unitegmic Ovule. | In order to understand how and what structures of the tomato ovule with a single integument form the seed coat of a mature seed, a detailed study of the main development stages of the tomato ovule integument was carried out using the methods of light and electron microscopy. The integument itself it was shown to transf... | 10.3390/plants11091101 | 35,567,102 | Plants (Basel, Switzerland) | 2,022 | ||
Gas chromatography coupled-to Fourier transform orbitrap mass spectrometer for enantioselective amino acid analyses: Application to pre-cometary organic analog. | Gas chromatography (GC) is a separation technique commonly developed for targeted in situ analyses in planetary space missions. It is coupled with low-resolution mass spectrometry to obtain additional structural information and allow compound identification. However, ground-based analyses of extraterrestrial samples ha... | 10.1016/j.chroma.2023.464118 | 37,315,448 | D000596:Amino Acids; D008401:Gas Chromatography-Mass Spectrometry; D005583:Fourier Analysis; D013237:Stereoisomerism; D013058:Mass Spectrometry | Journal of chromatography. A | 2,023 | D000596:Amino Acids |
On the vegetative network of guinea pig thoracic spinal cord. | A dense AChE-positive network was visualized by light microscopy in the thoracic spinal cord of grown-up guinea pigs of both sexes (bodyweight 250-300 g). This network connects in a horizontal and vertical direction the preganglionic sympathetic nuclei (n. intermediolateralis pars principalis (ILp), n. intermediolatera... | 10.1007/BF00489966 | 955,977 | D000110:Acetylcholinesterase; D000818:Animals; D001339:Autonomic Fibers, Preganglionic; D005260:Female; D006168:Guinea Pigs; D008297:Male; D009638:Norepinephrine; D013116:Spinal Cord; D013569:Synapses | Histochemistry | 1,976 | D000110:Acetylcholinesterase; D009638:Norepinephrine |
A happy marriage can help fight flu this winter, new research has claimed. A study conducted by the University of Birmingham found that people over 65 with happy marriages have a much higher level of antibodies in their blood than those in unhappy marriages and can better ward off infection. The study looked at whether... | 10.7748/nop.17.9.5.s7 | 27,741,891 | Nursing older people | 2,005 | |||
[Salivary gland cancer: new therapeutic approaches]. | Salivary gland carcinomas are rare, characterized by a diversity of histological subtypes associated with variable clinical behavior and prognosis with usually a poor response to chemotherapy. In this context, molecular alterations have been identified and represent potential therapeutic targets: overexpression of huma... | 10.53738/REVMED.2023.19.827.958 | 37,195,109 | D006801:Humans; D005260:Female; D002277:Carcinoma; D012468:Salivary Gland Neoplasms; D009154:Mutation; D011379:Prognosis; D001943:Breast Neoplasms; D014408:Biomarkers, Tumor | Revue medicale suisse | 2,023 | D014408:Biomarkers, Tumor |
Metabolic fate of a high concentration of glutamine and glutamate in rat brain slices: a ¹³C NMR study. | This study was performed to analyze the metabolic fate of a high concentration (5 mM) of glutamine and glutamate in rat brain slices and the participation of these amino acids in the glutamine-glutamate cycle. For this, brain slices were incubated for 60 min with [3-¹³C]glutamine or [3-¹³C]glutamate. Tissue plus medium... | 10.1016/j.neuint.2011.02.018 | 21,338,644 | D000818:Animals; D001921:Brain; D002247:Carbon Isotopes; D004734:Energy Metabolism; D018698:Glutamic Acid; D005973:Glutamine; D008297:Male; D019906:Nuclear Magnetic Resonance, Biomolecular; D051381:Rats; D017208:Rats, Wistar | Neurochemistry international | 2,011 | D002247:Carbon Isotopes; D005973:Glutamine; D018698:Glutamic Acid |
Acquired optic nerve and peripapillary pits in pathologic myopia. | PURPOSE
To examine the incidence and characteristics of pit-like structures around the optic disc and myopic conus in eyes with high myopia.
DESIGN
Prospective, observational case series.
PARTICIPANTS
We evaluated 198 eyes of 119 patients with pathologic myopia (spherical equivalent >-8 diopters [D]). We also evalu... | 10.1016/j.ophtha.2012.01.047 | 22,494,632 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004108:Dilatation, Pathologic; D058453:Emmetropia; D005124:Eye Abnormalities; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative; D009898:Optic Disk; D009900:Optic Nerve; D011446:Prospective Studies;... | Ophthalmology | 2,012 | |
Soft drinks and dental health: a review of the current literature. | In recent years there has been increased interest in the role of commercial soft drinks in dental diseases namely as dental caries and erosion. The objective of this paper has been to review the past and current literature to determine the present knowledge on this subject. The literature related to dental caries, eros... | 10.1016/j.jdent.2004.11.006 | 16,157,439 | D000367:Age Factors; D002253:Carbonated Beverages; D002326:Cariogenic Agents; D002327:Cariostatic Agents; D019343:Citric Acid; D003731:Dental Caries; D005459:Fluorides; D006801:Humans; D006863:Hydrogen-Ion Concentration; D014077:Tooth Erosion | Journal of dentistry | 2,006 | D002326:Cariogenic Agents; D002327:Cariostatic Agents; D019343:Citric Acid; D005459:Fluorides |
[Weaning failure: follow-up care by the weaning centres--home visits to patients with invasive ventilation]. | BACKGROUND
At present health-care at home for the majority of patients with invasive ventilation is mainly provided by nursing personnel. The reason for this unsatisfying condition is the lack of a basic medical supply for patients with invasive ventilation outside of hospitals. In contrast, current guidelines recommen... | 10.1055/s-0031-1291439 | 22,113,453 | D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D005858:Germany; D006699:Home Care Services; D006792:House Calls; D006801:Humans; D008297:Male; D008875:Middle Aged; D012121:Respiration, Artificial | Pneumologie (Stuttgart, Germany) | 2,012 | |
Sensitivity of BCG to modern antibiotics. | The viability of bacillus Calmette-Guérin (BCG) in intravesical instillation therapy has been demonstrated to be crucial for the prevention of bladder tumour recurrence. The aim of the present study was to determine the effects of modern antibacterial chemotherapeutics on BCG viability, particularly cycloserine, which ... | 10.1159/000052378 | 10,575,268 | D000283:Administration, Intravesical; D000900:Anti-Bacterial Agents; D000904:Antibiotics, Antitubercular; D001500:BCG Vaccine; D003523:Cycloserine; D004352:Drug Resistance, Microbial; D006801:Humans; D008826:Microbial Sensitivity Tests; D009163:Mycobacterium bovis; D001749:Urinary Bladder Neoplasms | European urology | 2,000 | D000900:Anti-Bacterial Agents; D000904:Antibiotics, Antitubercular; D001500:BCG Vaccine; D003523:Cycloserine |
Role of central and peripheral opioid receptors in the cardioprotection of intravenous morphine preconditioning. | BACKGROUND
Both central and peripheral opioid receptors activation produce cardioprotection. This study investigates the role of central and peripheral opioid receptors in intravenous morphine preconditioning (MPC) and ischemic preconditioning (IPC).
METHODS
Sixty-five anesthetized, open chests, male Sprague-Dawley r... | 10.1007/s11845-011-0734-0 | 21,800,037 | D000818:Animals; D019157:Ischemic Preconditioning, Myocardial; D008297:Male; D009020:Morphine; D009203:Myocardial Infarction; D015428:Myocardial Reperfusion Injury; D009270:Naloxone; D009292:Narcotic Antagonists; D009294:Narcotics; D000644:Quaternary Ammonium Compounds; D051381:Rats; D017207:Rats, Sprague-Dawley; D0119... | Irish journal of medical science | 2,011 | D009292:Narcotic Antagonists; D009294:Narcotics; D000644:Quaternary Ammonium Compounds; D011957:Receptors, Opioid; D009270:Naloxone; C041269:N-methylnaloxone; D009020:Morphine |
Granular dystrophy of the cornea. Contact lens fitting after phototherapeutic keratectomy. | We performed a phototherapeutic keratectomy using excimer laser 193-nm ablation in a patient with granular dystrophy of the cornea. The hyperopic shift caused by the 5-mm diameter tissue ablation could effectively be corrected by a high oxygen-transmissible, aspheric, rigid contact lenses 1 week after treatment. Cornea... | 7,743,809 | D000293:Adolescent; D003261:Contact Lenses; D003315:Cornea; D003317:Corneal Dystrophies, Hereditary; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D053685:Laser Therapy; D017755:Prosthesis Fitting; D014792:Visual Acuity | Cornea | 1,995 | ||
Honey characterization using computer vision system and artificial neural networks. | This paper reports the development of a computer vision system (CVS) for non-destructive characterization of honey based on colour and its correlated chemical attributes including ash content (AC), antioxidant activity (AA), and total phenolic content (TPC). Artificial neural network (ANN) models were applied to transf... | 24,767,037 | D000975:Antioxidants; D003116:Color; D003124:Colorimetry; D006722:Honey; D007091:Image Processing, Computer-Assisted; D016571:Neural Networks, Computer; D010636:Phenols | Food chemistry | 2,014 | D000975:Antioxidants; D010636:Phenols | |
Glutathione depletion induces glycogenolysis dependent ascorbate synthesis in isolated murine hepatocytes. | The relationship between glutathione deficiency, glycogen metabolism and ascorbate synthesis was investigated in isolated murine hepatocytes. Glutathione deficiency caused by various agents increased ascorbate synthesis with a stimulation of glycogen breakdown. Increased ascorbate synthesis from UDP-glucose or gulonola... | 10.1016/0014-5793(96)00548-0 | 8,690,080 | D000082:Acetaminophen; D000818:Animals; D001205:Ascorbic Acid; D003994:Bucladesine; D019328:Buthionine Sulfoximine; D000242:Cyclic AMP; D003958:Diamide; D005632:Fructose; D005978:Glutathione; D006003:Glycogen; D008099:Liver; D008297:Male; D008717:Methionine Sulfoximine; D051379:Mice; D013400:Sugar Acids; D014532:Uridin... | FEBS letters | 1,996 | D013400:Sugar Acids; D003958:Diamide; D014812:Vitamin K; D008717:Methionine Sulfoximine; D005632:Fructose; C007895:gulonolactone; D000082:Acetaminophen; D019328:Buthionine Sulfoximine; D003994:Bucladesine; D006003:Glycogen; D000242:Cyclic AMP; D005978:Glutathione; D001205:Ascorbic Acid; D014532:Uridine Diphosphate Gluc... |
Occurrence of a pneumothorax secondary to malpositioned nasogastric tube: a case report. | We report on the case of a 79-year-old man undergoing a Whipple operation with postoperative unstable respiratory status. Non-invasive ventilation therapy was started and a nasogastric tube (NGT) was placed to lower the risk of gastric accumulation of air. The NGT was placed following recommended clinical procedures. F... | 18,946,433 | D000368:Aged; D006801:Humans; D007441:Intubation, Gastrointestinal; D008297:Male; D011030:Pneumothorax | Minerva anestesiologica | 2,008 | ||
Ultrasmall All-In-One Nanodots Formed via Carbon Dot-Mediated and Albumin-Based Synthesis: Multimodal Imaging-Guided and Mild Laser-Enhanced Cancer Therapy. | Integration of multiple diagnostic/therapeutic modalities into a single system with ultrasmall size, excellent photothermal/photodynamic properties, high cellular uptake efficiency, nuclear delivery capacity, rapid renal clearance, and good biosafety is highly desirable for cancer theranostics, but still remains challe... | 10.1021/acsami.8b16065 | 30,403,472 | D000818:Animals; D002244:Carbon; D045744:Cell Line, Tumor; D006801:Humans; D051379:Mice; D064847:Multimodal Imaging; D009374:Neoplasms, Experimental; D010778:Photochemotherapy; D017319:Photosensitizing Agents; D045663:Quantum Dots; D012710:Serum Albumin, Bovine; D023041:Xenograft Model Antitumor Assays | ACS applied materials & interfaces | 2,018 | D017319:Photosensitizing Agents; D012710:Serum Albumin, Bovine; D002244:Carbon |
Profiling beneficial phytochemicals in a potato somatic hybrid for tuber peels processing: phenolic acids and anthocyanins composition. | The purpose of this study was to characterize the peels of a CN1 somatic hybrid obtained from two dihaploid potato lines (Cardinal H14 and Nicola H1) in terms of the health-promoting phenolic compounds (phenolic acids and anthocyanins). The CN1 hybrid is defined by a pink tuber skin color making it different from the l... | 10.1002/fsn3.2100 | 33,747,453 | Food science & nutrition | 2,021 | ||
Psychiatric manifestations revealing inborn errors of metabolism in adolescents and adults. | Inborn errors of metabolism (IEMs) may present in adolescence or adulthood as a psychiatric disorder. In some instances, an IEM is suspected because of informative family history or because psychiatric symptoms form part of a more diffuse clinical picture with systemic, cognitive or motor neurological signs. However, i... | 10.1007/s10545-007-0661-4 | 17,694,356 | D000293:Adolescent; D000328:Adult; D003071:Cognition; D003663:Decision Trees; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008661:Metabolism, Inborn Errors; D008875:Middle Aged; D009422:Nervous System Diseases; D009483:Neuropsychological Tests; D017410:Practice Guidelines as Topic; D009626:Terminol... | Journal of inherited metabolic disease | 2,007 | |
Effect of the knee position during wound closure after total knee arthroplasty on early knee function recovery. | OBJECTIVE
This study investigated the effect of the knee position during wound closure on early knee function recovery after total knee arthroplasty (TKA).
METHODS
This study included 80 primary total knee arthroplasties due to osteoarthritis. The patients were randomized according to the type of wound closure: exten... | 10.1186/s13018-014-0079-2 | 25,149,657 | D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee; D005260:Female; D006801:Humans; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee; D010147:Pain Measurement; D010149:Pain, Postoperative; D056888:Patient Positioning; D016059:Range of Motion, Articular; D... | Journal of orthopaedic surgery and research | 2,014 | |
Application of Coagulation-Membrane Rotation to Improve Ultrafiltration Performance in Drinking Water Treatment. | The combination of conventional and advanced water treatment is now widely used in drinking water treatment. However, membrane fouling is still the main obstacle to extend its application. In this study, the impact of the combination of coagulation and ultrafiltration (UF) membrane rotation on both fouling control and ... | 10.3390/membranes11080643 | 34,436,406 | Membranes | 2,021 | ||
Indirect modulation of human visual memory. | Conditions in which memories become maladaptive have inspired extensive research geared to modulate memory by targeting it directly and explicitly. Given limitations of direct memory modulation, we asked the following: can the target memories be modulated indirectly? To address this question, we uniquely targeted visua... | 10.1038/s41598-021-86550-2 | 33,790,311 | D000222:Adaptation, Physiological; D000328:Adult; D004538:Eidetic Imagery; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D008568:Memory; D014796:Visual Perception | Scientific reports | 2,021 | |
[Results of early operation of acute cholecystitis]. | Acute cholecystitis is a frequent complication of cholelithiasis. Patients in advanced age are more often affected than others. Early operation has been widely accepted for treatment of acute cholecystitis, as it has proved to be effective as prophylaxis against perforation, sepsis, recurrent inflammation, and long-ter... | 3,176,732 | D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D002763:Cholecystectomy; D002764:Cholecystitis; D002769:Cholelithiasis; D042882:Gallstones; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications; D011379:Prognosis; D013997:Time Factors | Zentralblatt fur Chirurgie | 1,988 | ||
State estimates of neonatal health-care costs associated with maternal smoking--United States, 1996. | Smoking during pregnancy can cause poor outcomes for both the pregnant woman and her unborn child and also result in added health-care expenditures. To characterize costs by state, CDC analyzed pregnancy risk surveillance and birth certificate data to estimate the association between maternal smoking and the probabilit... | 15,470,323 | D000328:Adult; D005260:Female; D017048:Health Care Costs; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D007348:Insurance, Health; D015931:Intensive Care, Neonatal; D008484:Medicaid; D011247:Pregnancy; D011256:Pregnancy Outcome; D011295:Prenatal Care; D012306:Risk; D012907:Smoking; D014481... | MMWR. Morbidity and mortality weekly report | 2,004 | ||
Functional group selective derivatization and gas-phase fragmentation reactions of plasmalogen glycerophospholipids. | A reaction strategy involving functional group selective modification of the O-alkenyl-ether double bond within plasmenyl ether containing lipids using iodine and methanol, in conjunction with functional group selective derivatization of amine-containing lipids using a novel (13)C1-S,S'-dimethylthiobutanoylhydroxysucci... | 10.5702/massspectrometry.S0015 | 24,349,934 | Mass spectrometry (Tokyo, Japan) | 2,013 | ||
Real-time en-face Gabor optical coherence tomographic angiography on human skin using CUDA GPU. | We recently proposed an optical coherence tomographic angiography (OCTA) algorithm, Gabor optical coherence tomographic angiography (GOCTA), which can extract microvascular signals from a spectral domain directly with lower computational complexity compared to other algorithms. In this manuscript, we combine a programm... | 10.1364/BOE.392499 | 32,499,961 | Biomedical optics express | 2,020 | ||
Rat platelets contain growth factor(s) distinct from PDGF which stimulate DNA synthesis in primary adult rat hepatocyte cultures. | Adult rat hepatocytes in primary cultures are stimulated to synthesize DNA in response to rat serum, whereas rat plasma is considerably less active. Biological activity is present in rat platelets and is secreted during aggregation in response to thrombin. The material secreted by rat platelets is heat labile and is se... | 10.1016/0014-4827(84)90670-0 | 6,468,536 | D000818:Animals; D001792:Blood Platelets; D002478:Cells, Cultured; D004261:DNA Replication; D006133:Growth Substances; D008099:Liver; D051379:Mice; D010982:Platelet-Derived Growth Factor; D051381:Rats; D011919:Rats, Inbred Strains; D014357:Trypsin | Experimental cell research | 1,984 | D006133:Growth Substances; D010982:Platelet-Derived Growth Factor; D014357:Trypsin |
A conceptual model of the role of complexity in the care of patients with multiple chronic conditions. | BACKGROUND
Effective healthcare for people with multiple chronic conditions (MCC) is a US priority, but the inherent complexity makes both research and delivery of care particularly challenging. As part of AHRQ Multiple Chronic Conditions Research Network (MCCRN) efforts, the Network developed a conceptual model to gui... | 10.1097/MLR.0000000000000045 | 24,561,762 | D002908:Chronic Disease; D015897:Comorbidity; D003695:Delivery of Health Care; D019033:Delivery of Health Care, Integrated; D019468:Disease Management; D006801:Humans; D033183:Interdisciplinary Communication; D008962:Models, Theoretical; D020380:Needs Assessment; D010348:Patient Care Team; D011320:Primary Health Care; ... | Medical care | 2,014 | |
Impaired beta-adrenergic mediated cerebral blood flow response in streptozotocin diabetic rats. | The influence of intracarotic infusion of isoproterenol on cerebral blood flow, on cerebrovascular CO2-reactivity, and on cerebral glucose metabolism were investigated in streptozotocin diabetic rats. Resting cerebral blood flow in diabetic rats decreased by 26% from a control value of 90 ml/100 g.min. to 66 ml/100 g.m... | 10.1111/j.1600-0773.1989.tb01181.x | 2,555,807 | D000818:Animals; D001784:Blood Gas Analysis; D001786:Blood Glucose; D002560:Cerebrovascular Circulation; D003921:Diabetes Mellitus, Experimental; D007545:Isoproterenol; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D011943:Receptors, Adrenergic, beta | Pharmacology & toxicology | 1,989 | D001786:Blood Glucose; D011943:Receptors, Adrenergic, beta; D007545:Isoproterenol |
CCR5 deficiency increased susceptibility to lipopolysaccharide-induced acute renal injury. | C-C chemokine receptor 5 (CCR5) regulates leukocyte chemotaxis and activation, and its deficiency exacerbates development of nephritis. Therefore, we investigated the role of CCR5 during lipopolysaccharide (LPS)-induced acute kidney injury. CCR5-deficient (CCR5-/-) and wild-type (CCR5+/+) mice, both aged about 10 month... | 10.1007/s00204-015-1530-9 | 26,055,553 | D058186:Acute Kidney Injury; D000818:Animals; D017209:Apoptosis; D015415:Biomarkers; D001806:Blood Urea Nitrogen; D002478:Cells, Cultured; D003404:Creatinine; D004195:Disease Models, Animal; D020022:Genetic Predisposition to Disease; D018836:Inflammation Mediators; D007668:Kidney; D008070:Lipopolysaccharides; D008264:M... | Archives of toxicology | 2,016 | D015415:Biomarkers; C000592874:CCR5 protein, mouse; D018836:Inflammation Mediators; D008070:Lipopolysaccharides; D019713:Receptors, CCR5; D014409:Tumor Necrosis Factor-alpha; D003404:Creatinine; D048051:p38 Mitogen-Activated Protein Kinases |
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