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Comparative effectiveness of a mindful eating intervention to a diabetes self-management intervention among adults with type 2 diabetes: a pilot study. | Mindful eating offers promise as an effective approach for weight management and glycemic control in people with diabetes. Diabetes self-management education (DSME) is an essential component of effective self-care. Yet, little research has compared the effect of mindful eating to DSME-based treatment. This study compar... | 23,102,183 | D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001786:Blood Glucose; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2; D003927:Diet, Diabetic; D004038:Diet, Reducing; D002149:Energy Intake; D015444:Exercise; D005260:Female; D006442:Glycated Hemoglobin; D006801:Humans; D007328:Insulin; D008297:Mal... | Journal of the Academy of Nutrition and Dietetics | 2,012 | D001786:Blood Glucose; D006442:Glycated Hemoglobin A; D007328:Insulin | |
Soft-Tissue Conditions Around Dental Implants: A Literature Review. | BACKGROUND
The aim of this article is to review the current understanding regarding periimplant soft-tissue conditions to minimize risk of periimplant mucositis and periimplantitis.
MATERIALS AND METHODS
An electronic search was performed in 4 different databases. Articles were reviewed and summarized if the followin... | 10.1097/ID.0000000000000871 | 30,913,109 | D015921:Dental Implants; D006801:Humans; D057873:Peri-Implantitis; D013280:Stomatitis | Implant dentistry | 2,019 | D015921:Dental Implants |
Influence of Surface and Structural Variations in Donor-Acceptor-Donor Sensitizers on Photoelectrocatalytic Water Splitting. | Conjugated organic chromophores composed of linked donor (D) and acceptor (A) moieties have attracted considerable attention for photoelectrochemical applications. In this work, we compare the optoelectronic properties and photoelectrochemical performance of two D-A-D structural isomers with thiophene-X-carboxylic acid... | 10.1021/acsami.1c11879 | 34,590,823 | ACS applied materials & interfaces | 2,021 | ||
Rapid anti-transglutaminase assay and patient interview for monitoring dietary compliance in celiac disease. | OBJECTIVE
The anti-transglutaminase antibodies (anti-tTG) play an important role in monitoring the celiacs' gluten-free diet (GFD).
MATERIAL AND METHODS
The authors propose to use the rapid IgA anti-tTG assay based on a whole blood drop to evaluate the compliance to GFD at the clinical ambulatory setting. The rapid t... | 10.3109/00365521.2013.786129 | 23,556,514 | D000293:Adolescent; D000328:Adult; D002446:Celiac Disease; D002648:Child; D055050:Diet, Gluten-Free; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D019204:GTP-Binding Proteins; D006801:Humans; D007070:Immunoglobulin A; D007407:Interviews as Topic; D008297:Male; D008875:Middle Aged;... | Scandinavian journal of gastroenterology | 2,013 | D007070:Immunoglobulin A; D000091345:Protein Glutamine gamma Glutamyltransferase 2; D011503:Transglutaminases; D019204:GTP-Binding Proteins |
Preparation of triple-negative breast cancer vaccine through electrofusion with day-3 dendritic cells. | Dendritic cells (DCs) are professional antigen-presenting cells (APCs) in human immune system. DC-based tumor vaccine has met with some success in specific malignancies, inclusive of breast cancer. In this study, we electrofused MDA-MB-231 breast cancer cell line with day-3 DCs derived from peripheral blood monocytes, ... | 10.1371/journal.pone.0102197 | 25,036,145 | D019496:Cancer Vaccines; D002459:Cell Fusion; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D018920:Coculture Techniques; D003713:Dendritic Cells; D004560:Electricity; D006801:Humans; D016219:Immunotherapy, Adoptive; D007371:Interferon-gamma; D018664:Interleukin-12; D010641:Phenotype; D013601:T-Lymphocytes; D01... | PloS one | 2,014 | D019496:Cancer Vaccines; D018664:Interleukin-12; D007371:Interferon-gamma |
Combination therapy with antibiotics and anthrax immune globulin intravenous (AIGIV) is potentially more effective than antibiotics alone in rabbit model of inhalational anthrax. | BACKGROUND
We have evaluated the therapeutic efficacy of AIGIV when given in combination with levofloxacin and the effective window of treatment to assess the added benefit provided by AIGIV over standard antibiotic treatment alone in a New Zealand white rabbit model of inhalational anthrax.
METHODS
Rabbits were expo... | 10.1371/journal.pone.0106393 | 25,226,075 | D000818:Animals; D000881:Anthrax; D000900:Anti-Bacterial Agents; D000942:Antigens, Bacterial; D001408:Bacillus anthracis; D016470:Bacteremia; D004195:Disease Models, Animal; D004359:Drug Therapy, Combination; D005260:Female; D016756:Immunoglobulins, Intravenous; D064704:Levofloxacin; D008297:Male; D011817:Rabbits; D012... | PloS one | 2,014 | D000900:Anti-Bacterial Agents; D000942:Antigens, Bacterial; D016756:Immunoglobulins, Intravenous; D064704:Levofloxacin |
Dietary patterns and frailty: a systematic review and meta-analysis. | CONTEXT
Assessing the relationship between single nutrients and frailty fails to take into consideration the interactions between nutrients. An increasing number of investigations in recent years have evaluated the association between dietary patterns and frailty.
OBJECTIVE
This systematic review and meta-analysis wa... | 10.1093/nutrit/nuz007 | 31,038,679 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D004032:Diet; D000072001:Diet, Healthy; D005260:Female; D000073496:Frailty; D005638:Fruit; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D012307:Risk Factors; D014675:Vegetables; D00... | Nutrition reviews | 2,019 | |
Combined Extracts of Epimedii Folium and Ligustri Lucidi Fructus with Budesonide Attenuate Airway Remodeling in the Asthmatic Rats by Regulating Apoptosis and Autophagy. | This study aimed to investigate the effects of the coadministration of budesonide (Bud) and the extracts of Epimedii Folium and Ligustri Lucidi Fructus (EEL) on regulating apoptosis and autophagy in asthmatic rats. Forty Sprague-Dawley rats were divided randomly into five groups (8 rats in each group): normal control (... | 10.1155/2020/2319409 | 32,831,860 | Evidence-based complementary and alternative medicine : eCAM | 2,020 | ||
[Establishment of Trace Amount Bone Marrow Hematopoietic Stem Cells of Adult Mouse Transplantation System]. | OBJECTIVE
To establish a transplantation system for a trace amount of adult mouse bone marrow hematopoietic stem cells (HSCs).
METHODS
The HSCs from bone marrow cells of GFP adult mouse were seperated by using marker combination ESLAM (CD45+CD201+CD150+CD48-) The goal cell population acquired by flow cytometry sortin... | 10.7534/j.issn.1009-2137.2018.04.039 | 30,111,427 | D000818:Animals; D001853:Bone Marrow; D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation; D046528:Chimerism; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells; D051379:Mice; D008810:Mice, Inbred C57BL | Zhongguo shi yan xue ye xue za zhi | 2,018 | |
Doped silica fibre thermoluminescence measurements of radiation dose in the use of 223Ra. | Using tailor-made sub-mm dimension doped-silica fibres, thermoluminescent dosimetric studies have been performed for α-emitting sources of 223RaCl2 (the basis of the Bayer Healthcare product Xofigo®). The use of 223RaCl2 in the palliative treatment of bone metastases resulting from late-stage castration-resistant prost... | 10.1016/j.apradiso.2017.04.019 | 28,427,834 | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine | 2,018 | ||
Increased macroH2A1.1 expression correlates with poor survival of triple-negative breast cancer patients. | PURPOSE
Epithelial-Mesenchymal Transition (EMT) features appear to be key events in development and progression of breast cancer. Epigenetic modifications contribute to the establishment and maintenance of cancer subclasses, as well as to the EMT process. Whether histone variants contribute to these transformations is ... | 10.1371/journal.pone.0098930 | 24,911,873 | D017398:Alternative Splicing; D045744:Cell Line, Tumor; D044127:Epigenesis, Genetic; D058750:Epithelial-Mesenchymal Transition; D015972:Gene Expression Regulation, Neoplastic; D006657:Histones; D006801:Humans; D011379:Prognosis; D016019:Survival Analysis; D064726:Triple Negative Breast Neoplasms | PloS one | 2,014 | D006657:Histones; C120756:macroH2A histone |
Coagulation factor binding orientation and dimerization may influence infectivity of adenovirus-coagulation factor complexes. | Adenoviruses (Ads) are promising vectors for therapeutic interventions in humans. When injected into the bloodstream, Ad vectors can bind several vitamin K-dependent blood coagulation factors, which contributes to virus sequestration in the liver by facilitating transduction of hepatocytes. Although both coagulation fa... | 10.1128/JVI.01070-13 | 23,804,638 | D000260:Adenoviruses, Human; D000818:Animals; D016466:CHO Cells; D006224:Cricetinae; D003412:Cricetulus; D005167:Factor VII; D005170:Factor X; D005822:Genetic Vectors; D057809:HEK293 Cells; D022781:Hepatocytes; D006801:Humans; D008958:Models, Molecular; D056004:Molecular Dynamics Simulation; D020836:Protein Structure, ... | Journal of virology | 2,013 | D005167:Factor VII; D005170:Factor X |
Changes in synaptic plasticity and expression of glutamate receptor subunits in the CA1 and CA3 areas of the hippocampus after transient global ischemia. | Excess glutamate release from the presynaptic membrane has been thought to be the major cause of ischemic neuronal death. Although both CA1 and CA3 pyramidal neurons receive presynaptic glutamate input, transient cerebral ischemia induces CA1 neurons to die while CA3 neurons remain relatively intact. This suggests that... | 27,090,818 | D000818:Animals; D056547:CA1 Region, Hippocampal; D056654:CA3 Region, Hippocampal; D016923:Cell Death; D018698:Glutamic Acid; D002546:Ischemic Attack, Transient; D008297:Male; D009473:Neuronal Plasticity; D017208:Rats, Wistar; D018091:Receptors, AMPA; D017470:Receptors, Glutamate; D016194:Receptors, N-Methyl-D-Aspartat... | Neuroscience | 2,016 | D018091:Receptors, AMPA; D017470:Receptors, Glutamate; D016194:Receptors, N-Methyl-D-Aspartate; D018698:Glutamic Acid | |
Searching Deep and Wide: Advances in the Molecular Understanding of Dental Caries and Periodontal Disease. | During the past decades, remarkable progress has been made in the understanding of the molecular basis of the 2 most common oral diseases, dental caries and periodontal disease. Improvements in our knowledge of the diseases' underlying biology have illuminated previously unrecognized aspects of their pathogenesis. Impo... | 10.1177/0022034519877387 | 31,633,389 | D003731:Dental Caries; D006801:Humans; D064307:Microbiota; D009909:Oral Health; D010510:Periodontal Diseases; D010518:Periodontitis | Advances in dental research | 2,019 | |
Serial serum immunoglobulin levels in acute postinfectious glomerulonephritis. | In 102 children with acute postinfectious glomerulonephritis, serum immunoglobulin levels at six month follow-up were significantly lower than those on admission to hospital. For those with a normal C 3 level on admission, the admission level of IgG was lower than for the group as a whole, while serum IgA and IgM level... | 6,571,955 | D000208:Acute Disease; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003165:Complement System Proteins; D005921:Glomerulonephritis; D006801:Humans; D007136:Immunoglobulins; D007223:Infant; D011446:Prospective Studies; D013997:Time Factors | The New Zealand medical journal | 1,983 | D007136:Immunoglobulins; D003165:Complement System Proteins | |
The role of molecular analyses of B-cell and T-cell clonality in the study of B-cell lymphomagenesis. | While the simple detection of B-cell clonality does not imply B-cell malignancy, comprehensive analyses of B-cell clonality are crucial to investigate the pathobiology of B-cell lymphoproliferative disorders. Our recent studies in patients with Sjögren's syndrome have highlighted how multiple molecular analyses of B-ce... | 8,722,196 | D001402:B-Lymphocytes; D002999:Clone Cells; D018450:Disease Progression; D005821:Genetic Techniques; D006801:Humans; D016393:Lymphoma, B-Cell; D012859:Sjogren's Syndrome; D013601:T-Lymphocytes | Clinical and experimental rheumatology | 1,996 | ||
Development and clinical application of an quantitative head-band formed ocular compressor. | In order to investigate the efficiency of a new quantitative head-band formed ocular compressor to reduce intraocular pressure (IOP), ocular compression by this new reducer with 40 mmHg for 10 min was performed on 87 cataractous eyes of 78 cases. The changes of IOP (87 eyes) and anterior chamber depth (ACD) were observ... | 10.1007/BF02904793 | 12,658,788 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract; D002387:Cataract Extraction; D002648:Child; D019245:Compressive Strength; D004867:Equipment Design; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008365:Manometry; D008875:Middle Aged; D011300:Pr... | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban | 2,002 | |
Salubrious effect of vitamin E supplementation on renal stone forming risk factors in urogenital tuberculosis patients. | The incidence of renal calculi has been evaluated to be 25% in urogenital tuberculosis patients. The stone could be caused due to the host, the pathogenic organism, or possibly by the treatment. Studies were carried out to find out the efficacy of vitamin E supplementation in reducing the risk of stone formation in ren... | 10.1081/jdi-120038490 | 15,287,196 | D000328:Adult; D000995:Antitubercular Agents; D001707:Biopsy, Needle; D016022:Case-Control Studies; D015897:Comorbidity; D019587:Dietary Supplements; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D007669:Kidney Calculi... | Renal failure | 2,004 | D000995:Antitubercular Agents; D014810:Vitamin E |
Increased osteoclastic activity in acute Charcot's osteoarthropathy: the role of receptor activator of nuclear factor-kappaB ligand. | AIMS/HYPOTHESIS
Our aims were to compare osteoclastic activity between patients with acute Charcot's osteoarthropathy and diabetic and healthy controls, and to determine the effect of the receptor activator of nuclear factor-kappaB ligand (RANKL) and its decoy receptor osteoprotegerin (OPG).
METHODS
Peripheral blood ... | 10.1007/s00125-008-0992-1 | 18,389,210 | D001177:Arthropathy, Neurogenic; D001862:Bone Resorption; D018929:Cell Culture Techniques; D003922:Diabetes Mellitus, Type 1; D003924:Diabetes Mellitus, Type 2; D005260:Female; D006801:Humans; D016173:Macrophage Colony-Stimulating Factor; D008297:Male; D009000:Monocytes; D016328:NF-kappa B; D010010:Osteoclasts; D053245... | Diabetologia | 2,008 | D016328:NF-kappa B; D053245:RANK Ligand; D053246:Receptor Activator of Nuclear Factor-kappa B; C505688:TNFSF11 protein, human; D016173:Macrophage Colony-Stimulating Factor |
Embryonic loss from 30 to 60 days post breeding and the effect of palpation per rectum on pregnancy. | This study was conducted over a 12-mo period to determine the rate of bovine embryo death between 30 and 60 d of gestation. In addition, palpation per rectum as a means of pregnancy detection was evaluated as a possible cause of embryo death. Estrus was synchronized in Holstein heifers (n = 1358), weighing > or = 385 k... | 10.1016/0093-691x(94)00060-8 | 16,727,646 | Theriogenology | 1,995 | ||
Biochemical and immunological mechanisms by which sickle cell trait protects against malaria. | Sickle cell trait (HbAS) is the best-characterized genetic polymorphism known to protect against falciparum malaria. Although the protective effect of HbAS against malaria is well known, the mechanism(s) of protection remain unclear. A number of biochemical and immune-mediated mechanisms have been proposed, and it is l... | 10.1186/1475-2875-12-317 | 24,025,776 | D054884:Host-Pathogen Interactions; D006801:Humans; D016778:Malaria, Falciparum; D012805:Sickle Cell Trait | Malaria journal | 2,013 | |
Instrumentation of a handy microscopic probe for concurrent observation and measurement of active sweat secretion, and its applications. | Instrumentation for the concurrent, dynamic monitoring of active sweat glands and perspiration volume is described. A device for the measurement of the rate of sweat secretion was installed on the head part of a microscope. The combined apparatus (microscopic probe) is handy for use and its weight is very light (ca. 30... | 10.1016/s0731-7085(96)02027-4 | 9,226,590 | D000328:Adult; D015374:Biosensing Techniques; D002138:Calibration; D015444:Exercise; D006358:Hot Temperature; D006801:Humans; D008297:Male; D008853:Microscopy; D008875:Middle Aged; D008991:Monitoring, Physiologic; D010812:Physical Stimulation; D013315:Stress, Psychological; D013542:Sweat; D013545:Sweat Glands | Journal of pharmaceutical and biomedical analysis | 1,997 | |
Risk Assessment of Fluxametamide Resistance and Fitness Costs in Fall Armyworm (Spodoptera frugiperda). | The fall armyworm (FAW), Spodoptera frugiperda, is one of the most devastating invasive polyphagous pests, which has attracted recent global attention by developing resistance to various insecticidal active ingredients with independent mode of action. Fluxametamide, a newly commercialized isoxazoline insecticide, is ex... | 10.3390/toxics11040307 | 37,112,534 | Toxics | 2,023 | ||
Increasing the availability of Tai Chi to veterans through a training of trainers course. | PURPOSE
The purpose of this nurse-led project was to increase the number of interprofessional Tai Chi instructors for veterans through a 5-week (32 hours) training of trainers (ToT) course led by a Tai Chi master trainer.
METHODS
This project was designed to evaluate the effectiveness of using the ToT model to increa... | 10.1111/nuf.12419 | 31,804,720 | D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D026302:Tai Ji; D000070260:Teacher Training; D013663:Teaching; D014728:Veterans | Nursing forum | 2,020 | |
Apolipoprotein B48: a novel marker of metabolic risk in overweight children? | Clinical studies in adults indicate there is a positive and significant association between insulin resistance, dyslipidaemia, fasting intestinally derived lipoproteins [via apoB48 (apolipoprotein B48)] and visceral fat. All of these factors contribute to increased risk of CVD (cardiovascular disease). Since little is ... | 10.1042/BST0350484 | 17,511,634 | D050154:Adiposity; D000328:Adult; D053283:Apolipoprotein B-48; D015415:Biomarkers; D002318:Cardiovascular Diseases; D002648:Child; D003924:Diabetes Mellitus, Type 2; D005215:Fasting; D005260:Female; D006706:Homeostasis; D006801:Humans; D007333:Insulin Resistance; D050152:Intra-Abdominal Fat; D008055:Lipids; D008297:Mal... | Biochemical Society transactions | 2,007 | D053283:Apolipoprotein B-48; D015415:Biomarkers; D008055:Lipids |
The Emergency Dental Appointment: Restorative Emergencies Part 1 - Tooth Related Problems. | Dental emergencies affect a large proportion of the population. While there is ample information in the literature on how to manage medical emergencies in dental practice, there is little information on common dental emergencies and how to manage them. In the UK, the 2009 Adult Dental Health Survey reported 9% of denta... | 10.1308/205016817821281747 | 28,668,101 | D019232:Dental Restoration Failure; D003793:Dental Restoration, Permanent; D004630:Emergencies; D005792:General Practice, Dental; D006801:Humans; D009059:Mouth Diseases; D010147:Pain Measurement; D011795:Surveys and Questionnaires; D014076:Tooth Diseases; D006113:United Kingdom | Primary dental journal | 2,017 | |
A novel "ghost"-free tomographic image reconstruction method applicable to rotary-shadowed replica specimens. | Electron tomography by conventional filtered back-projection is often seriously impaired by anisotropic resolution due to unavoidable limitation in specimen tilt-angles. We propose a new approach to overcome the problem for thin film-like replica-type specimens in which internal density is supposed as homogenous and co... | 10.1016/j.ultramic.2007.06.005 | 18,054,167 | D000818:Animals; D002417:Cattle; D002531:Cerebellum; D007091:Image Processing, Computer-Assisted; D008854:Microscopy, Electron | Ultramicroscopy | 2,008 | |
The detection of cervical intraepithelial neoplasia by electrical impedance spectroscopy: the effects of acetic acid and tissue homogeneity. | OBJECTIVE
To evaluate the efficacy of an electrical impedance probe (Epitheliometer) in the diagnosis of high grade cervical intraepithelial neoplasia (CIN) in women referred with cervical smear abnormalities and to assess the effect of acetic acid (AA) and tissue boundaries on the measurements.
METHODS
A prospective... | 10.1016/j.ygyno.2009.08.010 | 19,744,703 | D019342:Acetic Acid; D000328:Adult; D017097:Electric Impedance; D005260:Female; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D012372:ROC Curve; D013057:Spectrum Analysis; D002583:Uterine Cervical Neoplasms; D055815:Young Adult; D002578:Uterine Cervical Dysplasia | Gynecologic oncology | 2,009 | D019342:Acetic Acid |
Normal organ volume assessment from abdominal CT. | We determined the normal distribution of abdominal organ volumes measured from abdominal computed tomographic (CT) images. A total of 149 adult abdominal CT studies were selected, and 711 organs (388 from males, 323 from females) were outlined by hand on each CT image by using a computer. More than 18000 organ outlines... | 10.1007/s00261-003-0139-2 | 15,024,516 | D000005:Abdomen; D000311:Adrenal Glands; D000886:Anthropometry; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007668:Kidney; D016014:Linear Models; D008099:Liver; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D009929:Organ Size; D010179:Pancreas... | Abdominal imaging | 2,004 | |
[Non-Hodgkin's lymphoma with protein S deficiency]. | Venous thrombosis is rare in children. It can be either acquired or of constitutional origin. Thrombosis during non-Hodgkin lymphoma remains exceptional and is usually locally associated to the tumoral process, raising the issue of its tumoral or cruoric nature. The treatment is based on anticoagulation concomitantly t... | 10.1016/j.arcped.2003.10.007 | 14,700,757 | D002675:Child, Preschool; D006801:Humans; D008228:Lymphoma, Non-Hodgkin; D008297:Male; D018455:Protein S Deficiency; D013479:Superior Vena Cava Syndrome; D020246:Venous Thrombosis | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie | 2,004 | |
Incretin-based therapies for treatment of postprandial dyslipidemia in insulin-resistant states. | PURPOSE OF REVIEW
In prediabetes and diabetes, hyperglycemia is often accompanied by fasting and postprandial hyperlipidemia. Incretin-based therapies are in increasing clinical use for treating hyperglycemia, but recent evidence emphasizes their ability to improve lipoprotein abnormalities. This is significant as heig... | 10.1097/MOL.0b013e32834d68f0 | 22,123,671 | D000818:Animals; D002914:Chylomicrons; D050171:Dyslipidemias; D052216:Glucagon-Like Peptide 1; D006801:Humans; D006943:Hyperglycemia; D054795:Incretins; D007333:Insulin Resistance; D007408:Intestinal Absorption; D050356:Lipid Metabolism; D019518:Postprandial Period | Current opinion in lipidology | 2,012 | D002914:Chylomicrons; D054795:Incretins; D052216:Glucagon-Like Peptide 1 |
Injecting illicit substances epidemic and infective endocarditis. | Infective endocarditis (IE) is not the most frequent infection acquainted in intravenous drug abusers (IVDAs). On the other hand, all physicians should keep a high index of suspicion and always consider this possibility when they are dealing with an infectious process in this special population group. Since Sir William... | 10.2174/187152610790410891 | 20,218,949 | D004696:Endocarditis; D006801:Humans; D015819:Substance Abuse, Intravenous | Infectious disorders drug targets | 2,010 | |
Metabolism of N-alkyl compounds during the biosynthesis of prostaglandins. N-Dealkylation during prostaglandin biosynthesis. | The microsomal fraction of ram seminal vesicles (RSV), when fortified with arachidonic acid, catalyzed the dealkylation of various N-methyl compounds. These included an analogous series of monomethyl- and dimethyl-substituted anilines as well as the drugs aminopyrine and benzphetamine. In contrast, S-alkyl and O-alkyl ... | 6,813,675 | D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids; D003640:Dealkylation; D005260:Female; D006168:Guinea Pigs; D066298:In Vitro Techniques; D007213:Indomethacin; D007700:Kinetics; D008297:Male; D051379:Mice; D008805:Mice, Inbred A; D008862:Microsomes, Liver; D010089:Oxidoreductases, N-Demethylating; D... | Molecular pharmacology | 1,982 | D001095:Arachidonic Acids; D004364:Pharmaceutical Preparations; D011453:Prostaglandins; D016718:Arachidonic Acid; C030154:4-chloro-N-methylaniline demethylase; D010089:Oxidoreductases, N-Demethylating; D007213:Indomethacin | |
[Evaluation of blood flow rate in the internal carotid system in various types of retinal vein occlusion]. | UNLABELLED
The aim of the study was to evaluate blood flow rate by means of Doppler pulsating ultrasonography focused in internal carotid artery, opthalmic artery and posterior ciliary arteries in patients with different types of retinal veins occlusion. The material included 8 patients with congestive venous retinopat... | 9,026,564 | D001158:Arteries; D001783:Blood Flow Velocity; D002343:Carotid Artery, Internal; D002924:Ciliary Body; D005451:Fluorescein Angiography; D006801:Humans; D007511:Ischemia; D009880:Ophthalmic Artery; D011673:Pulsatile Flow; D012170:Retinal Vein Occlusion; D014463:Ultrasonography | Klinika oczna | 1,996 | ||
Secondhand smoke emission levels in enclosed public places during Ramadan. | Secondhand smoke levels were assessed among a convenience sample of 15 public venues in Amman, Jordan, during Ramadan. PM2.5 measurements were taken inside each venue pre- and post-'iftar', when daily smoking abstinence can be broken at sundown. Cigarette smoking was observed in all venues post-iftar, and the median PM... | 10.1093/eurpub/cks119 | 22,915,790 | D000393:Air Pollutants; D016902:Air Pollution, Indoor; D004784:Environmental Monitoring; D006801:Humans; D007514:Islam; D007597:Jordan; D052638:Particulate Matter; D012907:Smoking; D014028:Tobacco Smoke Pollution | European journal of public health | 2,013 | D000393:Air Pollutants; D052638:Particulate Matter; D014028:Tobacco Smoke Pollution |
Effects of PP1/PP2A inhibitor calyculin A on the E-C coupling cascade in murine ventricular myocytes. | Calyculin A was used to examine the importance of phosphatases in the modulation of cardiac contractile magnitude in the absence of any neural or humoral stimulation. Protein phosphatase (PP)1 and PP2A activity, twitch contractions, intracellular Ca(2+) concentration ([Ca(2+)](i)) transients, action potentials, membran... | 10.1152/ajpheart.00536.2001 | 11,748,045 | D000818:Animals; D002118:Calcium; D020013:Calcium Signaling; D004791:Enzyme Inhibitors; D006352:Heart Ventricles; D066298:In Vitro Techniques; D007545:Isoproterenol; D007700:Kinetics; D008297:Male; D008387:Marine Toxins; D008564:Membrane Potentials; D051379:Mice; D009200:Myocardial Contraction; D009206:Myocardium; D010... | American journal of physiology. Heart and circulatory physiology | 2,002 | D004791:Enzyme Inhibitors; D008387:Marine Toxins; D010080:Oxazoles; D015221:Potassium Channels; C059041:calyculin A; D010762:Phosphorylase a; D010749:Phosphoprotein Phosphatases; D007545:Isoproterenol; D002118:Calcium |
A novel wire-type lead-selective electrode based on bis (1'-hydroxy-2'-acetonaphthone)-2,2'-diiminodiethylamine. | The preparation of a lead-selective electrode based on bis(1'-hydroxy-2'-acetonaphthone)-2,2'-diiminodiethylamine (L) as sensing material is reported. The plasticized PVC membrane containing 30% PVC, 67% ortho-nitrophenyloctylether (NPOE) and 3% ionophore L was directly coated on a graphite rod. This electrode exhibits... | 10.1002/adic.200790058 | 17,899,887 | D004492:Edetic Acid; D006863:Hydrogen-Ion Concentration; D007097:Imines; D007202:Indicators and Reagents; D017736:Ion-Selective Electrodes; D007854:Lead; D008024:Ligands; D009284:Naphthols; D011199:Potentiometry; D012545:Schiff Bases | Annali di chimica | 2,007 | D007097:Imines; D007202:Indicators and Reagents; D008024:Ligands; D009284:Naphthols; D012545:Schiff Bases; C524878:bis(1'-hydroxy-2'-acetonaphthone)-2,2'-diiminodiethylamine; D007854:Lead; D004492:Edetic Acid |
Targeting GPVI as a novel antithrombotic strategy. | While platelet activation is essential to maintain blood vessel patency and minimize loss of blood upon injury, untimely or excessive activity can lead to unwanted platelet activation and aggregation. Resultant thrombosis has the potential to block blood vessels, causing myocardial infarction or stroke. To tackle this ... | 10.2147/JBM.S39220 | 24,899,824 | Journal of blood medicine | 2,014 | ||
Evaluation of a novel ELISA for the tumor-associated antigen CA 72-4 in patients with ovarian cancer. | AIM
Cancer antigen 72-4 (CA 72-4) is an established tumor marker in ovarian cancer. We evaluated a new solid-phase ELISA (DRG TM-CA 72-4 ELISA).
MATERIALS & METHODS
Repeated measures of test samples and controls were performed to evaluate reliability and reproducibility. Afterward, we performed analyses on the sera o... | 10.4155/fsoa-2016-0040 | 28,116,127 | Future science OA | 2,016 | ||
T-495, a novel low cooperative M1 receptor positive allosteric modulator, improves memory deficits associated with cholinergic dysfunction and is characterized by low gastrointestinal side effect risk. | M1 muscarinic acetylcholine receptor (M1 R) activation can be a new therapeutic approach for the treatment of cognitive deficits associated with cholinergic hypofunction. However, M1 R activation causes gastrointestinal (GI) side effects in animals. We previously found that an M1 R positive allosteric modulator (PAM) w... | 10.1002/prp2.560 | 31,990,455 | D000494:Allosteric Regulation; D000818:Animals; D016466:CHO Cells; D018678:Cholinergic Agents; D003412:Cricetulus; D003967:Diarrhea; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D008297:Male; D008569:Memory Disorders; D051379:Mice; D051381:Rats; D043643:Receptor, Muscarinic M1; D012601:Scop... | Pharmacology research & perspectives | 2,020 | D018678:Cholinergic Agents; D043643:Receptor, Muscarinic M1; D012601:Scopolamine |
Persistent Leptospiruria in Five Dogs Despite Antimicrobial Treatment (2000-2017). | In dogs with leptospirosis, doxycycline therapy is recommended as the preferred therapy for its ability to eliminate the organism from all tissues, including the renal tubules. Elimination of organisms from the renal tubules terminates leptospiruria and prevents transmission of the organism. This report describes the d... | 10.5326/JAAHA-MS-6882 | 30,427,719 | D000818:Animals; D000900:Anti-Bacterial Agents; D001437:Bacteriuria; D004283:Dog Diseases; D004285:Dogs; D004318:Doxycycline; D000077422:Enrofloxacin; D007684:Kidney Tubules; D007922:Leptospirosis; D012189:Retrospective Studies | Journal of the American Animal Hospital Association | 2,019 | D000900:Anti-Bacterial Agents; D000077422:Enrofloxacin; D004318:Doxycycline |
Parameters influencing the dissolved oxygen in the boundary layer of rainbow trout (Oncorhynchus mykiss) embryos and larvae. | We investigated the influence of oxygen demand (developmental stage) and supply (hypoxia, water flow rate, the chorion and body movements) on the oxygen concentration within the boundary layer next to the chorion of embryos or skin of larvae of rainbow trout (Oncorhynchus mykiss). Oxygen microelectrodes were used to me... | 10.1242/jeb.02754 | 17,401,126 | D000704:Analysis of Variance; D000818:Animals; D002823:Chorion; D004625:Embryo, Nonmammalian; D005618:Fresh Water; D008839:Microelectrodes; D009068:Movement; D017686:Oncorhynchus mykiss; D010100:Oxygen | The Journal of experimental biology | 2,007 | D010100:Oxygen |
[Simulation in surgical training]. | BACKGROUND
Patient safety during operations hinges on the surgeon's skills and abilities. However, surgical training has come under a variety of restrictions. To acquire dexterity with decreasingly "simple" cases, within the legislative time constraints and increasing expectations for surgical results is the future cha... | 10.1007/s00106-016-0248-1 | 27,680,544 | D003198:Computer Simulation; D003194:Computer-Assisted Instruction; D000070856:High Fidelity Simulation Training; D006801:Humans; D008954:Models, Biological; D013517:Otorhinolaryngologic Surgical Procedures; D025321:Surgery, Computer-Assisted; D013663:Teaching; D013673:Technology Assessment, Biomedical; D014584:User-Co... | HNO | 2,017 | |
Striped dolphins as trace element biomonitoring tools in oceanic waters: Accounting for health-related variables. | In Europe, monitoring contaminant concentrations and their effects in the marine environment is required under the Marine Strategy Framework Directive (MSFD, 2008/56/EC). The striped dolphin (Stenella coeruleoalba) is the most abundant small cetacean species in Portuguese oceanic waters, representing a potential biomon... | 10.1016/j.scitotenv.2019.134410 | 31,678,876 | D000818:Animals; D000079687:Biological Monitoring; D050706:Stenella; D014131:Trace Elements; D014874:Water Pollutants, Chemical | The Science of the total environment | 2,020 | D014131:Trace Elements; D014874:Water Pollutants, Chemical |
Whole Body Irradiation Induces Diabetes and Adipose Insulin Resistance in Nonhuman Primates. | PURPOSE
Diabetes mellitus is a delayed effect of radiation exposure in human and nonhuman primates. Diabetes mellitus is characterized by peripheral tissue insulin resistance, and as a result, irradiation exposure may cause important changes in insulin-sensitive tissues such as muscle and adipose.
METHODS AND MATERIA... | 10.1016/j.ijrobp.2019.11.034 | 31,805,366 | D000273:Adipose Tissue; D000818:Animals; D001786:Blood Glucose; D001823:Body Composition; D004307:Dose-Response Relationship, Radiation; D005355:Fibrosis; D007333:Insulin Resistance; D008066:Lipolysis; D008253:Macaca mulatta; D008297:Male; D000069079:Radiation Exposure; D014916:Whole-Body Irradiation | International journal of radiation oncology, biology, physics | 2,020 | D001786:Blood Glucose |
Clinical evaluation of a 5.5 mm three-zone refractive multifocal intraocular lens. | PURPOSE
To evaluate the results of implanting the P359-TUV 5.5 mm three-zone refractive multifocal intraocular lens (IOL).
SETTING
Musashino Red Cross Hospital, Tokyo, Japan.
METHODS
The lens was implanted in 29 eyes of 19 patients who were followed for a mean of 13.5 months. Distance visual acuity (DVA), near visu... | 10.1016/s0886-3350(96)80124-6 | 8,915,806 | D005500:Follow-Up Studies; D006801:Humans; D007910:Lenses, Intraocular; D008875:Middle Aged; D018918:Phacoemulsification; D011183:Postoperative Complications; D011474:Prosthesis Design; D012189:Retrospective Studies; D016896:Treatment Outcome; D014792:Visual Acuity | Journal of cataract and refractive surgery | 1,996 | |
Clinical and Radiographic Evaluation Periodontal Intrabony Defects Treated With Guided Tissue Regeneration. A Pilot Study. | BACKGROUND
The aim of this clinical and radiographic study was to evaluate the effect of guided tissue regeneration using a bioabsorbable barrier in the treatment of intrabony defects in humans.
METHODS
Intrabony osseous defects (2 or 3 walls) around mandibular canines and premolars were treated in 10 systemically he... | 10.1902/jop.2002.73.4.353 | 29,538,993 | Journal of periodontology | 2,002 | ||
Effect of hypertension on cardiac mass and radial artery wall thickness. | In subjects with essential hypertension, increased cardiac and radial artery mass are positively associated. The mechanical factor that contributes in the larger extent to their enhancement is pulse pressure, not mean arterial pressure. | 10.1016/s0002-9149(00)01018-3 | 11,009,282 | D001794:Blood Pressure; D005260:Female; D006801:Humans; D006973:Hypertension; D006984:Hypertrophy; D017379:Hypertrophy, Left Ventricular; D008297:Male; D008875:Middle Aged; D011674:Pulse; D017534:Radial Artery; D012044:Regression Analysis | The American journal of cardiology | 2,000 | |
A cost-benefit analysis of the Quebec Network of Genetic Medicine. | Certain serious diseases, including several major genetic disorders, cannot be treated effectively unless they are detected before symptoms appear. In such cases, only systematic population screening can ensure that the necessary preventive treatment can be administered to affected individuals. The question of whether ... | 10.1016/0277-9536(85)90399-5 | 3,923,626 | D035843:Biomedical Research; D003362:Cost-Benefit Analysis; D005260:Female; D030342:Genetic Diseases, Inborn; D005821:Genetic Techniques; D005820:Genetic Testing; D006801:Humans; D007037:Hypothyroidism; D007223:Infant; D007231:Infant, Newborn; D010661:Phenylketonurias; D011247:Pregnancy; D011792:Quebec; D013661:Tay-Sac... | Social science & medicine (1982) | 1,985 | D014443:Tyrosine |
Molecular basis of hereditary C1q deficiency associated with SLE and IgA nephropathy in a Turkish family. | Two siblings (case 1 and case 2) with homozygous C1q deficiency are described. Both presented with a photosensitive rash, and during follow-up case one developed SLE with nephrotic range proteinuria. Case 2 had microscopic hematuria with a past history of macroscopic hematuria. Renal biopsies revealed mesangioprolifera... | 10.1038/ki.1996.359 | 8,840,296 | D000293:Adolescent; D001483:Base Sequence; D002648:Child; D002675:Child, Preschool; D015922:Complement C1q; D017931:DNA Primers; D005260:Female; D005922:Glomerulonephritis, IGA; D015432:Glomerulonephritis, Membranoproliferative; D017325:Hepatitis B Vaccines; D006720:Homozygote; D006801:Humans; D007114:Immunization; D00... | Kidney international | 1,996 | D017931:DNA Primers; D017325:Hepatitis B Vaccines; D015922:Complement C1q |
Influence of pH on sediment-associated sorption reactions of benzidine. | Benzidine has been marked as a priority chemical on the National Priorities List by the U.S. Environmental Protection Agency because of its carcinogenic nature. Benzidine sorbs to the sediment matrix after entering water-sediment ecosystems and undergoes at least three different fate processes, including cation exchang... | 10.1897/08-223.1 | 19,415,963 | D000327:Adsorption; D001560:Benzidines; D002021:Buffers; D019015:Geologic Sediments; D006863:Hydrogen-Ion Concentration; D007700:Kinetics | Environmental toxicology and chemistry | 2,009 | D001560:Benzidines; D002021:Buffers; C029876:benzidine |
The effect of aggression I: The increases of metabolic cost and mobilization of fat reserves in male striped hamsters. | Aggression can benefit individuals by enhancing their dominance and thereby their ability to acquire and retain resources that increase survival or fitness. Engaging in aggressive behavior costs energy and how animals manage their energy budget to accommodate aggression remains unclear. We conducted three experiments t... | 10.1016/j.yhbeh.2017.12.015 | 29,288,636 | D000273:Adipose Tissue; D000374:Aggression; D000818:Animals; D001522:Behavior, Animal; D001831:Body Temperature; D003345:Corticosterone; D006224:Cricetinae; D002149:Energy Intake; D004734:Energy Metabolism; D008053:Lipid Mobilization; D008066:Lipolysis; D008297:Male; D010101:Oxygen Consumption; D013974:Thyroxine; D0142... | Hormones and behavior | 2,018 | D014284:Triiodothyronine; D013974:Thyroxine; D003345:Corticosterone |
Seed priming with calcium chloride enhances wheat resistance against wheat aphid Schizaphis graminum Rondani. | BACKGROUND
Calcium is an essential macronutrient for plant growth. Although it has been shown that exogenous Ca application can increase plant resistance to abiotic stress, little is known about its potential to enhance plant tolerance to biotic stress. Here, we investigated whether pretreatment of wheat (Triticum aest... | 10.1002/ps.6513 | 34,146,457 | D000818:Animals; D001042:Aphids; D002122:Calcium Chloride; D052585:Phloem; D018515:Plant Leaves | Pest management science | 2,021 | D002122:Calcium Chloride |
Drug absorption VIII: Kinetics of GI absorption of methotrexate. | The absorption of methotrexate from the lumen of the rat small intestine, in situ, was found to obey Michaelis--Menten kinetics. The values of Vmax and Km for the absorption process were 4.78 X 10(-7) M/min and 1.49 X 10(-5) M, respectively. | 10.1002/jps.2600670434 | 641,772 | D000818:Animals; D007408:Intestinal Absorption; D007700:Kinetics; D008297:Male; D008727:Methotrexate; D009994:Osmolar Concentration; D051381:Rats | Journal of pharmaceutical sciences | 1,978 | D008727:Methotrexate |
Urban Stormwater Characterization, Control, and Treatment. | The following review presents a synthesis of 181 journal articles published during 2015 that represent progress toward better characterizing, controlling, and treating urban stormwater runoff. The review is structured by general topical areas related to (1) stormwater quality and quantity characterization; (2) engineer... | 10.2175/106143016X14696400495938 | 27,620,114 | D002947:Cities; D004323:Drainage, Sanitary; D062070:Hydrology; D061005:Ponds; D011891:Rain; D014865:Waste Disposal, Fluid; D014872:Water Movements; D060753:Water Quality; D053833:Wetlands | Water environment research : a research publication of the Water Environment Federation | 2,016 | |
Application of custom-made TMJ prosthesis in hemifacial microsomia. | A case of hemifacial microsomia in an adult female is presented. The ascending ramus and condyle was primarily reconstructed using an iliac crest free bone graft. Following resorption of the bone graft, a custom-made total TMJ device (TMJ Concepts, USA) was used to correct the deformity. The alternative available recon... | 10.1016/j.ijom.2009.04.012 | 19,464,850 | D019643:Arthroplasty, Replacement; D016025:Bone Transplantation; D003131:Combined Modality Therapy; D005146:Facial Asymmetry; D005260:Female; D006801:Humans; D008334:Mandible; D009971:Orthodontics, Corrective; D056948:Orthognathic Surgical Procedures; D011474:Prosthesis Design; D016059:Range of Motion, Articular; D0196... | International journal of oral and maxillofacial surgery | 2,009 | |
Cyto-insectotoxins, a novel class of cytolytic and insecticidal peptides from spider venom. | Eight linear cationic peptides with cytolytic and insecticidal activity, designated cyto-insectotoxins (CITs), were identified in Lachesana tarabaevi spider venom. The peptides showed antibiotic activity towards Gram-positive and Gram-negative bacteria at micromolar concentrations as well as toxicity to insects. The pr... | 10.1042/bj20071123 | 18,215,128 | D000595:Amino Acid Sequence; D000818:Animals; D002942:Circular Dichroism; D005260:Female; D051379:Mice; D008807:Mice, Inbred BALB C; D008969:Molecular Sequence Data; D010455:Peptides; D016415:Sequence Alignment; D013111:Spider Venoms | The Biochemical journal | 2,008 | D010455:Peptides; D013111:Spider Venoms |
In vitro metabolism, disposition, preclinical pharmacokinetics and prediction of human pharmacokinetics of DNDI-VL-2098, a potential oral treatment for Visceral Leishmaniasis. | The in vitro metabolism and in vivo pharmacokinetic (PK) properties of DNDI-VL-2098, a potential oral agent for Visceral Leishmaniasis (VL) were studied and used to predict its human pharmacokinetics. DNDI-VL-2098 showed a low solubility (10μM) and was highly permeable (>200nm/s) in the Caco-2 model. It was stable in v... | 25,261,338 | D000284:Administration, Oral; D000818:Animals; D000977:Antiparasitic Agents; D001682:Biological Availability; D018938:Caco-2 Cells; D006224:Cricetinae; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D006207:Half-Life; D022781:Hepatocytes; D006801:Humans; D007898:Leishmaniasis, Visceral; D008099:Liver; D051379:Mice... | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences | 2,014 | D000977:Antiparasitic Agents | |
Resonance assignments for the substrate binding domain of Hsp70 chaperone Ssa1 from Saccharomyces cerevisiae. | Hsp70 chaperone proteins play crucial roles in the cell. Extensive structural and functional studies have been performed for bacterial and mammalian Hsp70s. Ssa1 from Saccharomyces cerevisiae is a member of the Hsp70 family. In vivo and biochemical studies on Ssa1 have revealed that it regulates prion propagation and t... | 10.1007/s12104-015-9603-5 | 25,682,100 | D000251:Adenosine Triphosphatases; D018840:HSP70 Heat-Shock Proteins; D009587:Nitrogen Isotopes; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D066244:Proton Magnetic Resonance Spectroscopy; D012441:Saccharomyces cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D013379:Substrate Speci... | Biomolecular NMR assignments | 2,015 | D018840:HSP70 Heat-Shock Proteins; D009587:Nitrogen Isotopes; D029701:Saccharomyces cerevisiae Proteins; D000251:Adenosine Triphosphatases; C095973:SSA1 protein, S cerevisiae |
Expression of placental growth factor and a disintegrin and metalloprotease with a thrombospondin type motifs 1-4-8 during the three trimesters of rat pregnancy at the maternal-fetal interface. | The functional roles of the a disintegrin and metalloprotease with a thrombospondin type motifs (ADAMTS) gene family in reproductive physiology, reproductive organs developments and adult reproductive health are still under investigation. The expression of the anti-angiogenic proteases ADAMTS-1, ADAMTS-4 and ADAMTS-8 i... | 10.1111/ahe.12948 | 37,424,113 | D000818:Animals; D005260:Female; D011247:Pregnancy; D051381:Rats; D019483:Disintegrins; D010920:Placenta; D000072483:Placenta Growth Factor; D000071096:ADAMTS Proteins | Anatomia, histologia, embryologia | 2,023 | D019483:Disintegrins; D000072483:Placenta Growth Factor; D000071096:ADAMTS Proteins |
Prediction of outcome after spinal surgery-using The Dialogue Support based on the Swedish national quality register. | PURPOSE
To evaluate the predictive precision of the Dialogue Support, a tool for additional help in shared decision-making before surgery of the degenerative spine.
METHODS
Data in Swespine (Swedish national quality registry) of patients operated between 2007 and 2019 found the development of prediction algorithms ba... | 10.1007/s00586-021-07065-y | 34,837,113 | D006801:Humans; D007405:Intervertebral Disc Displacement; D008159:Lumbar Vertebrae; D012042:Registries; D013130:Spinal Stenosis; D013548:Sweden; D016896:Treatment Outcome | European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society | 2,022 | |
Obstetrical ultrasound in remote communities: an approach to health program evaluation. | This paper illustrates one approach to evaluating the impact of an obstetrical ultrasound outreach program in remote Indian communities. The pregnancy characteristics and obstetrical outcomes of 240 deliveries in 2 groups of communities with and without the program are compared. After controlling for maternal age, pari... | 2,676,128 | D000328:Adult; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007198:Indians, North American; D008350:Manitoba; D011247:Pregnancy; D011248:Pregnancy Complications; D012423:Rural Health; D014463:Ultrasonography | Canadian journal of public health = Revue canadienne de sante publique | 1,989 | ||
Systematized and efficient: organization of critical care in the future. | Since the advent of critical care in the twentieth century, the core elements that are the foundation for critical care systems, namely to care for critically ill and injured patients and to save lives, have evolved enormously. The past half-century has seen dramatic advancements in diagnostic, organ support, and treat... | 10.1186/s13054-022-04244-1 | 36,443,764 | D006801:Humans; D016638:Critical Illness; D003422:Critical Care; D010808:Physical Examination | Critical care (London, England) | 2,022 | |
Treatment planning for prostate brachytherapy using region of interest adjoint functions and a greedy heuristic. | We have developed an efficient treatment-planning algorithm for prostate implants that is based on region of interest (ROI) adjoint functions and a greedy heuristic. For this work, we define the adjoint function for an ROI as the sensitivity of the average dose in the ROI to a unit-strength brachytherapy source at any ... | 10.1088/0031-9155/48/24/006 | 14,727,752 | D000465:Algorithms; D001822:Body Burden; D001918:Brachytherapy; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms; D011874:Radiometry; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity | Physics in medicine and biology | 2,003 | |
Blockage of citrate export prevents TCA cycle fragmentation via Irg1 inactivation. | The metabolism of activated macrophages relies on aerobic glycolysis, while mitochondrial oxidation is disrupted. In lipopolysaccharide-activated macrophages, the citrate carrier (CIC) exports citrate from mitochondria to enhance glycolytic genes through histone acetylation. CIC inhibition or Slc25a1 knockdown reduces ... | 10.1016/j.celrep.2022.110391 | 35,172,156 | D000107:Acetylation; D000818:Animals; D001692:Biological Transport; D002352:Carrier Proteins; D019343:Citric Acid; D002952:Citric Acid Cycle; D006657:Histones; D006836:Hydro-Lyases; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D008262:Macrophage Activation; D008264:Macrophages; D008810:Mice, Inbred C57BL; D008928... | Cell reports | 2,022 | D002352:Carrier Proteins; D006657:Histones; D051795:Hypoxia-Inducible Factor 1, alpha Subunit; D013386:Succinates; C020723:citrate-binding transport protein; D009243:NAD; D019343:Citric Acid; D019802:Succinic Acid; D006836:Hydro-Lyases; C487648:Irg1 protein, mouse; C005229:itaconic acid |
Effects of eicosapentaenoic acid (20:5 omega 3) on stress reactivity in rats. | This study examined the effects of eicosapentaenoic acid (EPA) on cardiovascular responses to isolation stress in male rats. Group-reared rats, on a fat-free diet, were given olive oil (OL), or EPA in OL (1.47 X 10(-7) mol/hr) via 8 week osmotic pumps, or a dummy pump (DUM), 2 weeks prior to a 4 week isolation period. ... | 10.3181/00379727-182-1-rc1 | 3,008,158 | D000804:Angiotensin II; D000818:Animals; D001794:Blood Pressure; D001835:Body Weight; D015118:Eicosapentaenoic Acid; D006339:Heart Rate; D008297:Male; D009638:Norepinephrine; D051381:Rats; D011921:Rats, Inbred WKY; D012934:Social Isolation; D013315:Stress, Psychological | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) | 1,986 | D000804:Angiotensin II; D015118:Eicosapentaenoic Acid; D009638:Norepinephrine |
Visualization of non-synaptic release sites in the myenteric plexus of the snail Helix pomatia. | Following conventional glutaraldehyde-osmium tetroxide fixation, a rich myenteric plexus was detected in the gastrointestinal tract of the snail Helix pomatia. Although hundreds of nerve processes were observed in the extensive myoneural neuropil, true synaptic specializations were not recognized in them. In the absenc... | 10.1016/0306-4522(88)90015-2 | 3,393,276 | D000818:Animals; D006372:Helix, Snails; D008854:Microscopy, Electron; D009197:Myenteric Plexus; D012016:Reference Values | Neuroscience | 1,988 | |
Comprehensive multimodality blood conservation: 100 consecutive CABG operations without transfusion. | BACKGROUND
Despite the recent introduction of a number of technical and pharmacologic blood conservation measures, bleeding and allogeneic transfusion remain persistent problems in open heart surgical procedures. We hypothesized that a comprehensive multimodality blood conservation program applied algorithmically on th... | 10.1016/s0003-4975(97)01004-7 | 9,456,106 | D000465:Algorithms; D016063:Blood Loss, Surgical; D001803:Blood Transfusion; D003131:Combined Modality Therapy; D001026:Coronary Artery Bypass; D003362:Cost-Benefit Analysis; D006801:Humans; D007430:Intraoperative Care; D011182:Postoperative Care; D011300:Preoperative Care; D011446:Prospective Studies; D012307:Risk Fac... | The Annals of thoracic surgery | 1,998 | |
Targeting EGF-receptor(s) - STAT1 axis attenuates tumor growth and metastasis through downregulation of MUC4 mucin in human pancreatic cancer. | Transmembrane proteins MUC4, EGFR and HER2 are shown to be critical in invasion and metastasis of pancreatic cancer. Besides, we and others have demonstrated de novo expression of MUC4 in ~70-90% of pancreatic cancer patients and its stabilizing effects on HER2 downstream signaling in pancreatic cancer. Here, we found ... | 10.18632/oncotarget.3286 | 25,686,822 | D000077716:Afatinib; D000818:Animals; D017209:Apoptosis; D015153:Blotting, Western; D021441:Carcinoma, Pancreatic Ductal; D002465:Cell Movement; D049109:Cell Proliferation; D066246:ErbB Receptors; D005260:Female; D005455:Fluorescent Antibody Technique; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D00... | Oncotarget | 2,015 | C524658:MUC4 protein, human; D009025:Morpholines; D055264:Mucin-4; D011799:Quinazolines; D012333:RNA, Messenger; D050794:STAT1 Transcription Factor; C494079:STAT1 protein, human; D000077716:Afatinib; C420268:Canertinib; C512478:EGFR protein, human; D066246:ErbB Receptors |
Biochemical and Biological Attributes of Matrix Metalloproteinases. | Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that are involved in the degradation of various proteins in the extracellular matrix (ECM). Typically, MMPs have a propeptide sequence, a catalytic metalloproteinase domain with catalytic zinc, a hinge region or linker peptide, and a hemopex... | 10.1016/bs.pmbts.2017.02.005 | 28,413,025 | D000818:Animals; D005109:Extracellular Matrix; D006801:Humans; D020782:Matrix Metalloproteinases; D008954:Models, Biological; D015398:Signal Transduction; D013379:Substrate Specificity | Progress in molecular biology and translational science | 2,017 | D020782:Matrix Metalloproteinases |
Definition of immune molecular subtypes with distinct immune microenvironment, recurrence, and PANoptosis features to aid clinical therapeutic decision-making. | Objective: Cervical cancer poses a remarkable health burden to females globally. Despite major advances in early detection and treatment modalities, some patients still relapse. The present study proposed a novel immune molecular classification that reflected distinct recurrent risk and therapeutic responses in cervica... | 10.3389/fgene.2022.1007108 | 36,313,466 | Frontiers in genetics | 2,022 | ||
[Detection of human papilloma virus in cytologic samples or biopsies of the cervix]. | BACKGROUND
The DNA quality for the detection and typification of Human Papilloma Virus (HPV) varies according to the type of sample in which it is studied. This may affect the sensitivity and specificity of the method employed.
AIM
To study the yield and specificity of HPV detection and typification in uterine cervic... | 10.4067/s0034-98872005000600003 | 16,075,126 | D001706:Biopsy; D002584:Cervix Uteri; D004279:DNA, Viral; D005260:Female; D005914:Globins; D006801:Humans; D027383:Papillomaviridae; D016612:Paraffin Embedding; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D016707:Tissue Fixation; D014626:Vaginal Smears | Revista medica de Chile | 2,005 | D004279:DNA, Viral; D005914:Globins |
Evidence for cysteine persulfide as reaction product of L-Cyst(e)ine C-S-lyase (C-DES) from Synechocystis. Analyses using cystine analogues and recombinant C-DES. | The pyridoxal phosphate-dependent monomeric L-cysteine/cystine C-S-lyase (C-DES), previously isolated from Synechocystis PCC 6714 by its capacity to direct [2Fe-2S] cluster assembly of ferredoxin in vitro (Leibrecht, I., and Kessler, D. (1997) J. Biol. Chem. 272, 10442-10447), has now been cloned, sequenced, and overex... | 10.1074/jbc.274.1.189 | 9,867,829 | D000595:Amino Acid Sequence; D013437:Carbon-Sulfur Lyases; D003001:Cloning, Molecular; D000458:Cyanobacteria; D003545:Cysteine; D003553:Cystine; D004269:DNA, Bacterial; D004220:Disulfides; D008969:Molecular Sequence Data; D011994:Recombinant Proteins; D017386:Sequence Homology, Amino Acid | The Journal of biological chemistry | 1,999 | D004269:DNA, Bacterial; D004220:Disulfides; D011994:Recombinant Proteins; C116840:cysteine persulfide; D003553:Cystine; D013437:Carbon-Sulfur Lyases; C105473:L-cysteine-cystine C-S lyase; D003545:Cysteine |
Use of APAAP technique on paraffin wax embedded bone marrow trephines. | The immunoalkaline phosphatase (APAAP) technique was applied to the labelling of decalcified sections of formalin fixed, paraffin wax embedded bone marrow trephine biopsy specimens. A panel of monoclonal antibodies reactive with haemopoietic and epithelial antigens, which survive routine formalin fixation, was assessed... | 10.1136/jcp.42.11.1201 | 2,685,054 | D000469:Alkaline Phosphatase; D001706:Biopsy; D001853:Bone Marrow; D006652:Histological Techniques; D006801:Humans; D007124:Immunoenzyme Techniques; D007938:Leukemia; D008228:Lymphoma, Non-Hodgkin; D010232:Paraffin; D014885:Waxes | Journal of clinical pathology | 1,989 | D014885:Waxes; D010232:Paraffin; D000469:Alkaline Phosphatase |
Folded free vascularized fibula transfer. | A technique of improved free vascularized fibula grafting for bone defects up to 15 cm in length is presented with three illustrative cases. By dividing a harvested free fibula graft at its midpoint without dividing its vascular pedicle, two vascularized bone lengths are produced that require only one set of anastomose... | 10.1097/00006534-198808000-00017 | 3,399,561 | D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms; D002812:Chondroma; D005260:Female; D005266:Femoral Neoplasms; D005360:Fibula; D005870:Giant Cell Tumors; D006801:Humans; D006811:Humerus; D008297:Male; D008875:Middle Aged; D013518:Surgery, Plastic | Plastic and reconstructive surgery | 1,988 | |
Crystalluria in normal subjects and in stone formers with and without thiazide and cellulose phosphate treatment. | Quantitative and qualitative studies have been made of the urinary crystals from a series of normal subjects and from stone formers with idiopathic hypercalciuria with and without treatment with thiazide diuretics and/or cellulose phosphate. The results obtained from mid-morning unprepared subjects seemed more helpful ... | 10.1111/j.1464-410x.1976.tb06696.x | 13,904 | D000328:Adult; D001581:Benzothiadiazines; D002118:Calcium; D002130:Calcium Phosphates; D002482:Cellulose; D002986:Clinical Trials as Topic; D003460:Crystallization; D004232:Diuretics; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007669:Kidney Calculi; D010070:Oxalates; D010710:Phosphates; D049993:Sodium Chlorid... | British journal of urology | 1,976 | D001581:Benzothiadiazines; D002130:Calcium Phosphates; D004232:Diuretics; D010070:Oxalates; D010710:Phosphates; D049993:Sodium Chloride Symporter Inhibitors; D002482:Cellulose; D002118:Calcium |
Low serum 25-hydroxyvitamin D in hereditary hemochromatosis: relation to iron status. | Under normal conditions, vitamin D absorbed from the diet or synthesized in the skin is transported to the liver where it undergoes hydroxylation. The purpose of this study was to determine whether excess hepatic iron affects this process and the subsequent production of 1,25-dihydroxyvitamin D (1,25-[OH]2D) in the kid... | 10.1016/s0016-5085(85)80001-9 | 3,838,288 | D001219:Aspartate Aminotransferases; D001815:Bloodletting; D002112:Calcifediol; D002117:Calcitriol; D005260:Female; D005293:Ferritins; D006432:Hemochromatosis; D006801:Humans; D007501:Iron; D008099:Liver; D008103:Liver Cirrhosis; D008297:Male; D014168:Transferrin; D014807:Vitamin D | Gastroenterology | 1,985 | D014168:Transferrin; D014807:Vitamin D; D005293:Ferritins; D007501:Iron; D001219:Aspartate Aminotransferases; D002117:Calcitriol; D002112:Calcifediol |
Strong aggregation and increased toxicity of polyleucine over polyglutamine stretches in mammalian cells. | Expansion of a Glutamine (Gln) repeat above a specific critical size in certain proteins gives rise to aggregation-prone proteins that cause neurodegenerative disorders, such as Huntington's disease. However, proteins with long hydrophilic polyglutamine repeats are more frequently found in nature than proteins with lon... | 10.1093/hmg/11.13.1487 | 12,045,202 | D000911:Antibodies, Monoclonal; D002460:Cell Line; D005455:Fluorescent Antibody Technique; D006801:Humans; D010455:Peptides; D011506:Proteins; D012091:Repetitive Sequences, Nucleic Acid; D014162:Transfection; D014407:Tumor Cells, Cultured | Human molecular genetics | 2,002 | D000911:Antibodies, Monoclonal; D010455:Peptides; D011506:Proteins; C027819:polyleucine; C097188:polyglutamine |
[CBP35-CBP67 interaction in stress response and aging]. | Three carbohydrate-binding proteins with relative molecular masses of 35, 67, and 70 kDa (CBP35, CBP67, and CBP70) have been described to be present in nuclei of mammalian cells, where they are associated with nuclear ribonucleoprotein (RNP) complexes. CBP35 consists of two domains, an N-terminal domain that is homolog... | 8,091,839 | D000375:Aging; D000818:Animals; D000943:Antigens, Differentiation; D001143:Arousal; D002352:Carrier Proteins; D002467:Cell Nucleus; D037502:Galectin 3; D008099:Liver; D008297:Male; D008970:Molecular Weight; D051381:Rats; D017208:Rats, Wistar; D011956:Receptors, Cell Surface | Zeitschrift fur Gerontologie | 1,994 | D000943:Antigens, Differentiation; D002352:Carrier Proteins; D037502:Galectin 3; D011956:Receptors, Cell Surface; C055213:saccharide-binding proteins | |
Characterization of a new zeaxanthin producing strain of Chlorella saccharophila isolated from New Zealand marine waters. | A fast growing strain of Chlorella saccharophila was isolated from the marine water of New Zealand and grown in heterotrophic conditions using glucose or glycerol as a carbon source. Biomass production was found to be higher in culture fed with glucose (2.14±0.08 g L(-1)) as compared to glycerol (0.378±0.04 g L(-1)). L... | 23,811,063 | D001483:Base Sequence; D002708:Chlorella; D017931:DNA Primers; D009520:New Zealand; D016133:Polymerase Chain Reaction; D012623:Seawater; D024341:Xanthophylls; D065146:Zeaxanthins | Bioresource technology | 2,013 | D017931:DNA Primers; D024341:Xanthophylls; D065146:Zeaxanthins | |
Effects of shell sand burial on seedling emergence, growth and stoichiometry of Periploca sepium Bunge. | BACKGROUND
Sand burial plays an irreplaceable and unique role in the growth and distribution of vegetation on the Shell Dike Island in the Yellow River Delta. There are still some unknown on the effects of sand burial on the morphology, biomass, and especially the stoichiometry of Periploca sepium, as well as the relat... | 10.1186/s12870-020-2319-4 | 32,164,525 | D018533:Biomass; D002681:China; D018525:Germination; D031109:Periploca; D000080463:Sand; D036226:Seedlings; D012639:Seeds | BMC plant biology | 2,020 | D000080463:Sand |
Psychological Distress in Healthcare Workers During the Covid-19 Pandemic: Development and Validation of the Italian Version of the Healthcare Workers Emergency Distress Questionnaire (HEDQ). | Objective
The COVID-19 pandemic has presented unprecedented challenges for health systems as it has proven to be an extraordinary emergency. Exposure to such chronic stress can have detrimental effects on the psychophysical well-being of healthcare workers, with possible manifestation of stress-related symptoms. The pr... | 10.36131/cnfioritieditore20220403 | 36,101,647 | Clinical neuropsychiatry | 2,022 | ||
Dimethylarginine dimethylaminohydrolase 1 deficiency aggravates monocrotaline-induced pulmonary oxidative stress, pulmonary arterial hypertension and right heart failure in rats. | Patients with pulmonary arterial hypertension (PAH) and right ventricular (RV) failure have a poor clinical outcome, but the mechanisms of PAH and RV failure development are not totally clear. PAH is associated with reduced NO bioavailability and increased endogenous NOS inhibitor asymmetric dimethylarginine (ADMA). Di... | 10.1016/j.ijcard.2019.07.078 | 31,402,164 | D000581:Amidohydrolases; D000818:Animals; D004195:Disease Models, Animal; D006333:Heart Failure; D006976:Hypertension, Pulmonary; D008297:Male; D009569:Nitric Oxide; D018384:Oxidative Stress; D051381:Rats; D017207:Rats, Sprague-Dawley; D018497:Ventricular Dysfunction, Right; D016278:Ventricular Function, Right | International journal of cardiology | 2,019 | D009569:Nitric Oxide; D000581:Amidohydrolases; C059999:dimethylargininase |
A Smart Visual Sensing Concept Involving Deep Learning for a Robust Optical Character Recognition under Hard Real-World Conditions. | In this study, we propose a new model for optical character recognition (OCR) based on both CNNs (convolutional neural networks) and RNNs (recurrent neural networks). The distortions affecting the document image can take different forms, such as blur (focus blur, motion blur, etc.), shadow, bad contrast, etc. Document-... | 10.3390/s22166025 | 36,015,785 | D000077321:Deep Learning; D016571:Neural Networks, Computer; D000068997:Smartphone | Sensors (Basel, Switzerland) | 2,022 | |
Epoprostenol sodium (prostacyclin) infusion in acute myocardial infarction. | Epoprostenol (prostacyclin) is a potent inhibitor of platelet aggregation and causes relaxation of vascular smooth muscle. These effects may be beneficial in patients with acute myocardial infarction. The effect of epoprostenol infusion in patients with acute myocardial infarction was evaluated in a randomised double b... | 10.1136/hrt.56.5.428 | 3,539,163 | D000293:Adolescent; D000328:Adult; D000368:Aged; D001794:Blood Pressure; D002986:Clinical Trials as Topic; D004311:Double-Blind Method; D011464:Epoprostenol; D005260:Female; D006339:Heart Rate; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction; D011897:Rand... | British heart journal | 1,986 | D011464:Epoprostenol |
Nonneural markers in Alzheimer disease. | Nonneural tissues are now widely used to search for abnormalities in genes as well as for other markers of dementia of the Alzheimer type (DAT). Studies of nonneural tissues can experimentally circumvent problems inherent in the study of autopsy brain, but to be meaningful, abnormalities identified in the periphery mus... | 10.1097/00002093-199206040-00003 | 1,290,624 | D000368:Aged; D000544:Alzheimer Disease; D015415:Biomarkers; D001921:Brain; D005819:Genetic Markers; D006801:Humans | Alzheimer disease and associated disorders | 1,992 | D015415:Biomarkers; D005819:Genetic Markers |
[The characteristics of general anesthesia in ocular surgery]. | The general anesthesia is recommended in ocular surgical interventions on children or patients with psychical lability, anxiety and in general intervention on open globe. Before the intervention, a permanent contact between the ophthalmologist and the anesthesiologist is necessary, in order to manage the complexity of ... | 8,507,620 | D000762:Anesthesia Recovery Period; D000768:Anesthesia, General; D006801:Humans; D007442:Intubation, Intratracheal; D013508:Ophthalmologic Surgical Procedures; D011229:Preanesthetic Medication | Oftalmologia (Bucharest, Romania : 1990) | 1,993 | ||
GM-144, a novel lipophilic vaginal contraceptive gel-microemulsion. | In a systematic effort to develop a dual-function intravaginal spermicide as well as a drug delivery vehicle against sexually transmitted pathogens, a submicron particle size (30-80 nm), lipophilic and spermicidal gel-microemulsion (viz GM-144) containing the pharmaceutical excipients propylene glycol, Captex 300, Crem... | 10.1208/pt020205 | 14,727,880 | D000282:Administration, Intravaginal; D000818:Animals; D001696:Biomechanical Phenomena; D003271:Contraceptive Agents, Female; D004334:Drug Administration Schedule; D004337:Drug Carriers; D004353:Drug Evaluation, Preclinical; D004655:Emulsions; D005260:Female; D006801:Humans; D008297:Male; D017137:Nonoxynol; D009821:Oil... | AAPS PharmSciTech | 2,001 | D003271:Contraceptive Agents, Female; D004337:Drug Carriers; D004655:Emulsions; D009821:Oils; D013089:Spermatocidal Agents; D014622:Vaginal Creams, Foams, and Jellies; D017137:Nonoxynol |
Determination of isosorbide-5-mononitrate in human plasma by high-resolution gas chromatography. | A method for the determination of isosorbide-5-mononitrate (5-ISMN) in human plasma by capillary gas chromatography with electron-capture detection was developed and applied to clinical samples. 9-Fluorenone was used as an internal standard, ethyl acetate was employed for liquid-liquid extraction. The advantage of the ... | 10.1016/j.jchromb.2003.10.069 | 14,698,265 | D002849:Chromatography, Gas; D004129:Dimethylpolysiloxanes; D005449:Fluorenes; D006801:Humans; D007202:Indicators and Reagents; D007548:Isosorbide Dinitrate; D011786:Quality Control; D012015:Reference Standards; D015203:Reproducibility of Results; D012828:Silicones; D012996:Solutions; D014665:Vasodilator Agents | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences | 2,004 | D004129:Dimethylpolysiloxanes; D005449:Fluorenes; D007202:Indicators and Reagents; D012828:Silicones; D012996:Solutions; D014665:Vasodilator Agents; C013830:baysilon; C028401:9-fluorenone; D007548:Isosorbide Dinitrate; C030397:isosorbide-5-mononitrate |
The role of title, metadata and abstract in identifying clinically relevant journal articles. | Access to current clinical information involves searches of bibliographic databases, such as MEDLINE, and subsequent evaluation of retrieval results for relevance to a specific clinical situation and quality of the reported research. We establish the amount of information that needs to be provided by an information ret... | 16,779,028 | D000043:Abstracting and Indexing; D034201:Computers, Handheld; D016206:Databases, Bibliographic; D003658:Decision Making, Computer-Assisted; D006801:Humans; D016247:Information Storage and Retrieval; D016239:MEDLINE; D039781:PubMed | AMIA ... Annual Symposium proceedings. AMIA Symposium | 2,005 | ||
Normal platelet counts mask abnormal thrombopoiesis in patients with chronic myeloid leukemia. | Increased platelet heterogeneity has been reported in myeloproliferative neoplasms (MPN) with thrombocytosis. However, whether abnormal thrombopoiesis occurs in patients with chronic myeloid leukemia (CML) who have normal platelet counts, remains unclear. In order to explore this question, 25 patients with CML with nor... | 10.3892/ol.2015.3502 | 26,622,857 | Oncology letters | 2,015 | ||
Calcaneus bone mineral density in Japanese women with rheumatoid arthritis. | OBJECTIVES
The aim of this study was to investigate the relationships among bone mineral densities (BMD) in the calcaneus and leg activity of daily living (L-ADL) in rheumatoid arthritis (RA) patients.
METHODS
We measured and compared calcaneus BMD using single X-ray absorptiometry and lumbar spine and femoral neck B... | 10.1007/s00296-003-0421-1 | 14,991,230 | D015502:Absorptiometry, Photon; D000203:Activities of Daily Living; D000328:Adult; D017677:Age Distribution; D000368:Aged; D001172:Arthritis, Rheumatoid; D015519:Bone Density; D002111:Calcaneus; D016022:Case-Control Studies; D015897:Comorbidity; D005260:Female; D005272:Femur Neck; D005500:Follow-Up Studies; D006801:Hum... | Rheumatology international | 2,005 | |
Effect of collagen fibres and elastic lamellae content on the mechanical behaviour of abdominal aortic aneurysms. | PURPOSE
The main purpose of this study was a detailed analysis of the mechanical and structural characteristics of human abdominal aneurysms in comparison with normal abdominal aortae and determination of the correlations between their mechanical behaviour and the microstructural content.
METHODS
Various mechanical p... | 33,518,720 | D000368:Aged; D016880:Anisotropy; D017544:Aortic Aneurysm, Abdominal; D001696:Biomechanical Phenomena; D003094:Collagen; D004548:Elasticity; D005260:Female; D006801:Humans; D008297:Male; D013314:Stress, Mechanical; D017540:Tunica Media | Acta of bioengineering and biomechanics | 2,020 | D003094:Collagen | |
Using multielectrode arrays to investigate neurodegenerative effects of the amyloid-beta peptide. | BACKGROUND
Multielectrode arrays are widely used to analyze the effects of potentially toxic compounds, as well as to evaluate neuroprotective agents upon the activity of neural networks in short- and long-term cultures. Multielectrode arrays provide a way of non-destructive analysis of spontaneous and evoked neuronal ... | 10.1186/s42234-021-00078-4 | 34,711,287 | Bioelectronic medicine | 2,021 | ||
Diffusion-Weighted Imaging Image Combined with Transcranial Doppler Ultrasound in the Diagnosis of Patients with Cerebral Infarction and Vertigo. | This study aimed at exploring the application value of diffusion-weighted imaging (DWI) combined with transcranial Doppler (TCD) in the diagnosis of patients with cerebral infarction and vertigo (CI + V). In this article, using a retrospective case-control study, 100 CI + V patients (CI + V group) were examined by DWI ... | 10.1155/2022/5313238 | 35,833,063 | D016022:Case-Control Studies; D002544:Cerebral Infarction; D006801:Humans; D012189:Retrospective Studies; D017585:Ultrasonography, Doppler, Transcranial; D014717:Vertigo | Contrast media & molecular imaging | 2,022 | |
Enantioselectivity of racemic metolachlor and S-metolachlor in maize seedlings. | Chiral herbicides may have enantioselective effects on plants. In this study, we assessed and compared the enantioselectivity of the chiral herbicides rac-metolachlor and S-metolachlor to maize seedlings. The superoxide dismutase activity (SOD) activity of roots and stem leaves treated by rac-metolachlor was 1.38 and 1... | 10.1080/03601234.2010.515173 | 20,954,044 | D000081:Acetamides; D006540:Herbicides; D009195:Peroxidase; D010940:Plant Proteins; D036226:Seedlings; D013237:Stereoisomerism; D013482:Superoxide Dismutase; D003313:Zea mays | Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes | 2,010 | D000081:Acetamides; D006540:Herbicides; D010940:Plant Proteins; D009195:Peroxidase; D013482:Superoxide Dismutase; C051786:metolachlor |
Neck and shoulder pain in adolescents seldom occur alone: Results from the Norwegian Ungdata Survey. | BACKGROUND
No previous studies have investigated the prevalence of co-occurring neck/shoulder pain, other musculoskeletal pain, headache and depressive symptoms in adolescents. This study aimed to describe the prevalence of isolated neck/shoulder pain and the co-occurrence of neck/shoulder pain with other musculoskelet... | 10.1002/ejp.1785 | 33,909,331 | D000293:Adolescent; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D059352:Musculoskeletal Pain; D019547:Neck Pain; D009664:Norway; D015995:Prevalence; D020069:Shoulder Pain; D011795:Surveys and Questionnaires | European journal of pain (London, England) | 2,021 | |
Detection of human papillomavirus type 16 E6/E7 transcripts in histologically cancer-free pelvic lymph nodes of patients with cervical carcinoma. | Human papillomavirus (HPV) 16 E6/E7 mRNAs have been detected in paraffin-embedded sections of histologically cancer-free pelvic lymph nodes from four of six patients with HPV 16-associated cervical cancer. The cDNA obtained from the viral mRNA by reverse transcription was amplified by the polymerase chain reaction (PCR... | 10.1006/gyno.1994.1033 | 8,314,141 | D000328:Adult; D002277:Carcinoma; D004279:DNA, Viral; D005260:Female; D006801:Humans; D008198:Lymph Nodes; D008875:Middle Aged; D009856:Oncogene Proteins, Viral; D027383:Papillomaviridae; D050725:Papillomavirus E7 Proteins; D010388:Pelvis; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger; D012097:Repressor Pro... | Gynecologic oncology | 1,994 | D004279:DNA, Viral; C068651:E6 protein, Human papillomavirus type 16; D009856:Oncogene Proteins, Viral; D050725:Papillomavirus E7 Proteins; D012333:RNA, Messenger; D012097:Repressor Proteins; C059731:oncogene protein E7, Human papillomavirus type 16 |
Caffeine-increased radiosensitivity is not dependent on a loss of G2/M arrest or apoptosis in bladder cancer cell lines. | PURPOSE
Bladder cancer cell lines UCRU-BL-13, UCRU-BL-17/2 and UCRU-BL-28, with differing p53 status and molecular responses to irradiation, were used to investigate possible mechanisms for caffeine-induced radiosensitization.
MATERIALS AND METHODS
After treatment with caffeine and exposure to X-radiation, radiosensi... | 10.1080/095530099140410 | 10,331,854 | D017209:Apoptosis; D002110:Caffeine; D002453:Cell Cycle; D002470:Cell Survival; D016195:G2 Phase; D006801:Humans; D008938:Mitosis; D011836:Radiation Tolerance; D011838:Radiation-Sensitizing Agents; D014407:Tumor Cells, Cultured; D001749:Urinary Bladder Neoplasms | International journal of radiation biology | 1,999 | D011838:Radiation-Sensitizing Agents; D002110:Caffeine |
Liquid-vapor interfacial properties of aqueous solutions of guanidinium and methyl guanidinium chloride: influence of molecular orientation on interface fluctuations. | The guanidinium cation (C(NH2)3(+)) is a highly stable cation in aqueous solution due to its efficient solvation by water molecules and resonance stabilization of the charge. Its salts increase the solubility of nonpolar molecules ("salting-in") and decrease the ordering of water. It is one of the strongest denaturants... | 10.1021/jp405862p | 23,937,431 | D000388:Air; D000465:Algorithms; D002244:Carbon; D002412:Cations; D019791:Guanidine; D016014:Linear Models; D008760:Methylguanidine; D008958:Models, Molecular; D056004:Molecular Dynamics Simulation; D010100:Oxygen; D012996:Solutions; D012997:Solvents; D013499:Surface Properties; D014867:Water | The journal of physical chemistry. B | 2,013 | D002412:Cations; D012996:Solutions; D012997:Solvents; D014867:Water; D008760:Methylguanidine; D002244:Carbon; D019791:Guanidine; D010100:Oxygen |
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