title large_stringlengths 0 979 | abstract large_stringlengths 1 94.7k | doi large_stringlengths 0 71 | pmid int64 21 38.1M | mesh_terms large_stringlengths 0 1.47k | journal large_stringlengths 1 239 | pubdate int16 1.97k 2.02k | chemical_list large_stringlengths 0 1.47k |
|---|---|---|---|---|---|---|---|
Depression of delayed outward K+ current by Co2+ in guinea pig ventricular myocytes. | Effects of Co2+ on the delayed outward K+ current (IK) in guinea pig ventricular myocytes were studied using the whole cell patch-clamp technique. IK was activated by depolarizing voltage pulses positive to -30 mV and reached half-maximal activation at +24 mV. Co2+ shifted the activation curve to a more depolarized vol... | 10.1152/ajpcell.1991.261.1.C23 | 1,858,857 | D000818:Animals; D003035:Cobalt; D006168:Guinea Pigs; D066298:In Vitro Techniques; D007700:Kinetics; D008564:Membrane Potentials; D009132:Muscles; D009206:Myocardium; D011188:Potassium; D015221:Potassium Channels | The American journal of physiology | 1,991 | D015221:Potassium Channels; D003035:Cobalt; D011188:Potassium |
In vitro effects of radiation on human retinoblastoma cells. | Retinoblastoma (Rb) is the most common intraocular tumor of childhood and has been demonstrated clinically to be very sensitive to external beam radiation (EBR). The purpose of this study was to determine the survival of Rb cell lines at different endpoints following irradiation. We also studied Rb-reconstituted cell l... | 10.1002/ijc.10344 | 11,992,382 | D000165:Acridine Orange; D017209:Apoptosis; D002460:Cell Line; D002470:Cell Survival; D004249:DNA Damage; D004307:Dose-Response Relationship, Radiation; D004996:Ethidium; D005434:Flow Cytometry; D005456:Fluorescent Dyes; D006801:Humans; D008854:Microscopy, Electron; D012175:Retinoblastoma; D016160:Retinoblastoma Protei... | International journal of cancer | 2,001 | D005456:Fluorescent Dyes; D016160:Retinoblastoma Protein; D004996:Ethidium; D000165:Acridine Orange |
Osteopontin can act as an effector for a germline mutation of BRCA1 in malignant transformation of breast cancer-related cells. | Breast cancer-associated 1 (BRCA1) plays an important role in breast cancer initiation and progression through its functions in the cell cycle and DNA repair processes; however, its role in metastatic development in human breast cancer is still poorly understood. We have previously shown that osteopontin (OPN) expressi... | 10.1111/j.1349-7006.2010.01561.x | 20,384,635 | D000818:Animals; D001943:Breast Neoplasms; D002448:Cell Adhesion; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D002471:Cell Transformation, Neoplastic; D005260:Female; D019398:Genes, BRCA1; D018095:Germ-Line Mutation; D006801:Humans; D009361:Neoplasm Invasiveness; D053495:Osteopontin; D051381:Rats; D017208:Rat... | Cancer science | 2,010 | D053495:Osteopontin |
Liver transplantation in 2013: challenges and controversies. | Liver transplantation has changed over the past 50 years from an experimental surgery to a life saving intervention that is the treatment of choice for selected patients with end stage liver disease. Since Starzl attempted the first liver transplant in 1963, the procedure has evolved into one that occurs over 12000 tim... | 23,831,904 | D006528:Carcinoma, Hepatocellular; D005544:Forecasting; D006801:Humans; D008108:Liver Diseases, Alcoholic; D008113:Liver Neoplasms; D016031:Liver Transplantation; D009927:Tissue and Organ Procurement; D016896:Treatment Outcome | Minerva gastroenterologica e dietologica | 2,013 | ||
Optogenetic manipulation of neural activity in C. elegans: from synapse to circuits and behaviour. | The emerging field of optogenetics allows for optical activation or inhibition of excitable cells. In 2005, optogenetic proteins were expressed in the nematode Caenorhabditis elegans for the first time. Since then, C. elegans has served as a powerful platform upon which to conduct optogenetic investigations of synaptic... | 10.1111/boc.201200069 | 23,458,457 | D000818:Animals; D017173:Caenorhabditis elegans; D005260:Female; D008027:Light; D008297:Male; D009474:Neurons; D062308:Optogenetics; D013569:Synapses | Biology of the cell | 2,013 | |
Renal replacement therapy in Korea, 2012. | The Korean Society of Nephrology (KSN) launched the official end-stage renal disease (ESRD) patient registry in 1985, and an Internet online registry program was opened in 2001 and revised in 2013. The ESRD Registry Committee of KSN has collected data on dialysis therapy in Korea through the online registry program in ... | 10.1016/j.krcp.2014.01.002 | 26,877,945 | Kidney research and clinical practice | 2,014 | ||
Identification and validation of an 18-gene signature highly-predictive of bladder cancer metastasis. | We found two deviant groups that were unpredictable with clinical models predicting bladder cancer metastasis. The group G consists of patients at high risk of pN+ , but they have pN0. The group P consists of patients at low risk of pN+ , but they have pN+ . We aimed to determine the genetic differences between these t... | 10.1038/s41598-017-18773-1 | 29,321,541 | D000368:Aged; D030541:Databases, Genetic; D055088:Early Detection of Cancer; D005260:Female; D020869:Gene Expression Profiling; D015972:Gene Expression Regulation, Neoplastic; D005819:Genetic Markers; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D000075983:Nectins; D018426:SEER Progr... | Scientific reports | 2,018 | D005819:Genetic Markers; C000619011:NECTIN2 protein, human; D000075983:Nectins |
The Janthinobacterium sp. HH01 genome encodes a homologue of the V. cholerae CqsA and L. pneumophila LqsA autoinducer synthases. | Janthinobacteria commonly form biofilms on eukaryotic hosts and are known to synthesize antibacterial and antifungal compounds. Janthinobacterium sp. HH01 was recently isolated from an aquatic environment and its genome sequence was established. The genome consists of a single chromosome and reveals a size of 7.10 Mb, ... | 10.1371/journal.pone.0055045 | 23,405,110 | D001426:Bacterial Proteins; D018441:Biofilms; D005798:Genes, Bacterial; D016680:Genome, Bacterial; D006714:Homoserine; D007783:Lactones; D016952:Legionella pneumophila; D042802:Oxalobacteraceae; D010802:Phylogeny; D053038:Quorum Sensing; D014157:Transcription Factors; D014734:Vibrio cholerae | PloS one | 2,013 | D001426:Bacterial Proteins; D007783:Lactones; C085427:LuxI protein, Bacteria; C091088:N-octanoylhomoserine lactone; D014157:Transcription Factors; D006714:Homoserine |
Angiographic cerebral circulation time before and after endovascular therapy for symptomatic vasospasm. | AIM
To investigate the correlation between angiographic cerebral circulation time (CCT) and cerebral blood flow (CBF) evaluated by single photon emission computed tomography (SPECT) before and after endovascular treatment for symptomatic vasospasm.
MATERIALS AND METHODS
Seven patients with unilateral vasospasm as dem... | 10.1053/crad.2000.0507 | 10,988,045 | D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D015906:Angioplasty, Balloon, Coronary; D002533:Cerebral Angiography; D002560:Cerebrovascular Circulation; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020768:Middle Cerebral Artery; D010208:Papaverine... | Clinical radiology | 2,000 | D014665:Vasodilator Agents; D010208:Papaverine |
Suprapubic cystostomy during renal transplantation in a patient with a urethral stricture after hypospadias surgery: A case report. | INTRODUCTION
Renal transplantation often causes polyuria, and a Foley catheter is typically placed after transplantation. A urethral stricture often makes it difficult to insert a normal diameter urethral catheter.
CASE PRESENTATION
We report on the case of a 16-year-old adolescent male with a history of hypospadias ... | 10.1002/iju5.12042 | 32,743,378 | IJU case reports | 2,019 | ||
Impact of Acquired Broad-Spectrum β-Lactamases on Susceptibility to Cefiderocol and Newly Developed β-Lactam/β-Lactamase Inhibitor Combinations in Escherichia coli and Pseudomonas aeruginosa. | The ability of broad-spectrum β-lactamases to reduce the susceptibility to ceftazidime-avibactam (CZA), ceftolozane-tazobactam (C/T), imipenem-relebactam, meropenem-vaborbactam, aztreonam-avibactam (AZA), and cefiderocol (FDC) was evaluated both in Pseudomonas aeruginosa and in Escherichia coli using isogenic backgroun... | 10.1128/aac.00039-22 | 35,315,685 | D000900:Anti-Bacterial Agents; D053961:Azabicyclo Compounds; D001398:Aztreonam; D002442:Ceftazidime; D002511:Cephalosporins; D004338:Drug Combinations; D004926:Escherichia coli; D004927:Escherichia coli Infections; D006801:Humans; D007769:Lactams; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa; D06... | Antimicrobial agents and chemotherapy | 2,022 | D000900:Anti-Bacterial Agents; D053961:Azabicyclo Compounds; D002511:Cephalosporins; D004338:Drug Combinations; D007769:Lactams; D065093:beta-Lactamase Inhibitors; D002442:Ceftazidime; D001618:beta-Lactamases; D001398:Aztreonam |
The bZIP Ap1 transcription factor is a negative regulator of virulence attributes of the anthropophilic dermatophyte Trichophyton rubrum. | Trichophyton rubrum is a fungus that causes chronic skin and nail infections in healthy individuals and immunocompromised patients. During infection, T. rubrum invades host cutaneous tissues by adapting to the acidic pH and the innate immune response of the host. Several genes are upregulated during the growth of T. ru... | 10.1016/j.crmicr.2022.100132 | 35,909,615 | Current research in microbial sciences | 2,022 | ||
Investigating carbohydrate isomers by IMS-CID-IMS-MS: precursor and fragment ion cross-sections. | Ion mobility spectrometry techniques (IMS and IMS-IMS) combined with collision-induced dissociation (CID) and mass spectrometry (MS) are used to investigate the structures of singly-lithiated carbohydrate isomers. With the exception of some favorable cases, IMS-MS analyses of underivatized carbohydrates reveal that mos... | 10.1039/c5an00840a | 26,306,702 | D006031:Glycosylation; D007536:Isomerism; D008094:Lithium; D013058:Mass Spectrometry; D009844:Oligosaccharides | The Analyst | 2,015 | D009844:Oligosaccharides; D008094:Lithium |
Inhalation solutions--which ones may be mixed? Physico-chemical compatibility of drug solutions in nebulizers--update 2013. | Many patients suffering from chronic respiratory diseases rely on inhalation therapy with nebulizers. About 25% of patients who need to inhale several different drugs per day save time by mixing them for simultaneous inhalation. This review presents a comprehensive overview of the available data concerning physico-chem... | 24,172,851 | D000280:Administration, Inhalation; D000900:Anti-Bacterial Agents; D001993:Bronchodilator Agents; D002908:Chronic Disease; D004338:Drug Combinations; D006801:Humans; D008171:Lung Diseases; D009330:Nebulizers and Vaporizers | Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society | 2,014 | D000900:Anti-Bacterial Agents; D001993:Bronchodilator Agents; D004338:Drug Combinations | |
Survival in sarcoidosis-associated pulmonary hypertension: the importance of hemodynamic evaluation. | OBJECTIVE
Pulmonary hypertension (PH) has been associated with increased mortality in patients with advanced pulmonary sarcoidosis. Sarcoidosis-associated PH may be the result of left ventricular dysfunction (LVD) or isolated pulmonary vasculature abnormality. Our objective was to determine if the cause of PH affects s... | 10.1378/chest.09-2002 | 20,348,196 | D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D006328:Cardiac Catheterization; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006976:Hypertension, Pulmonary; D008297:Male; D008875:Middle Aged; D009820:Ohio; D016016:Proportional Hazards Models; D011446:Prospective Studies; D01... | Chest | 2,010 | |
A case of familial glomerulopathy with fibronectin deposits caused by the Y973C mutation in fibronectin. | Glomerulopathy with fibronectin deposits is a rare hereditary kidney disease characterized by the extensive deposition of fibronectin in glomeruli, particularly in mesangial regions and subendothelial zones. Prognostically, the disease is known as slowly progressive, leading to kidney failure in most cases. We recently... | 23,219,110 | D000293:Adolescent; D005353:Fibronectins; D015432:Glomerulonephritis, Membranoproliferative; D006801:Humans; D008297:Male; D009154:Mutation; D010375:Pedigree; D055815:Young Adult | American journal of kidney diseases : the official journal of the National Kidney Foundation | 2,013 | D005353:Fibronectins | |
Integrated driver mutations profile of chinese gastrointestinal-natural killer/T-cell lymphoma. | Background
One of the most common nasal external sites in extranodal Natural Killer/T-cell lymphoma (NKTCL) is in the gastrointestinal (GI) system. Despite this, reports on gastrointestinal-Natural Killer/T-cell lymphoma (GI-NKTCL) are very few. To obtain a better understanding of this manifestation of NKTCL, we conduc... | 10.3389/fonc.2022.976762 | 36,059,700 | Frontiers in oncology | 2,022 | ||
Leiomyoma of the temporal artery. | A 25-year-old man had a right sided cyst-like swelling removed from his forehead. Histology revealed a well circumscribed spindle cell lesion with myxomatous changes. Immunohistochemical staining with muscle markers (smooth muscle actin, muscle specific actin) was positive. The histological features along with the immu... | 21,941,601 | BMJ case reports | 2,009 | |||
An unusual position of the gallbladder following nephrectomy for large neoplasms. | The cases of two children are presented in whom the gallbladder was found to lie in an unusual position in the ipsilateral renal fossa following nephrectomy for large neoplasms. This postoperative visceral position must be recognized, as the appearance on cross-sectional imaging can mimic postoperative fluid collection... | 10.1007/s002470050173 | 9,174,026 | D000293:Adolescent; D002675:Child, Preschool; D005704:Gallbladder; D006801:Humans; D007680:Kidney Neoplasms; D009364:Neoplasm Recurrence, Local; D009392:Nephrectomy; D011183:Postoperative Complications; D011859:Radiography; D009396:Wilms Tumor | Pediatric radiology | 1,997 | |
[Aneurysmal bone cysts of the spinal canal]. | Aneurysmal bone cysts (ABC) are rare bone tumors of controversial pathogenesis. In 15% of cases, they are localized in the vertebrae. Despite the absence of anaplasia, their volume and localization are often responsible for incomplete surgical resection. The authors present 5 cases of primary vertebral ABC, 4 females a... | 7,942,141 | D000293:Adolescent; D000328:Adult; D000368:Aged; D017824:Bone Cysts, Aneurysmal; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013122:Spinal Diseases | Acta medica portuguesa | 1,994 | ||
Variability in spectrophotometric pyruvate analyses for predicting onion pungency and nutraceutical value. | Onion pyruvate concentration is used as a predictor of flavor intensity and nutraceutical value. The protocol of Schwimmer and Weston (SW) (1961) is the most widespread methodology for estimating onion pyruvate. Anthon and Barret (AB) (2003) proposed modifications to this procedure. Here, we compared these spectrophoto... | 10.1016/j.foodchem.2016.12.031 | 28,159,256 | D002851:Chromatography, High Pressure Liquid; D019697:Onions; D019289:Pyruvic Acid; D015203:Reproducibility of Results; D013053:Spectrophotometry; D013649:Taste | Food chemistry | 2,017 | D019289:Pyruvic Acid |
Pharmacological effect of beta toxin of Clostridium perfringens type C on rats. | The biological effect of purified beta toxin of Clostridium perfringens type C in vivo was investigated. After intravenous injection of the purified beta toxin into rats, a rise in blood pressure and a simultaneous fall in heart rate were observed. After the blood pressure reached a maximum, the heart rate recovered gr... | 10.1111/j.1348-0421.1981.tb00045.x | 6,168,890 | D000317:Adrenergic alpha-Antagonists; D000818:Animals; D001427:Bacterial Toxins; D001794:Blood Pressure; D003016:Clostridium perfringens; D004305:Dose-Response Relationship, Drug; D005730:Ganglionic Blockers; D006339:Heart Rate; D006584:Hexamethonium Compounds; D008297:Male; D010643:Phenoxybenzamine; D010646:Phentolami... | Microbiology and immunology | 1,981 | D000317:Adrenergic alpha-Antagonists; D001427:Bacterial Toxins; C031884:CPB protein, Clostridium perfringens; D005730:Ganglionic Blockers; D006584:Hexamethonium Compounds; D010643:Phenoxybenzamine; D010646:Phentolamine |
A 1,8-naphthalimide-based turn-on fluorescent probe for imaging mitochondrial hydrogen peroxide in living cells. | Hydrogen peroxide (H2O2) produced from mitochondria has attracted much attention on account of its physiological and pathological functions. Therefore, monitoring mitochondrial H2O2 levels in living cells is of great significance for understanding its functions. We report here a mitochondria-targeted H2O2 probe, Mito-H... | 10.1080/10715762.2018.1446530 | 30,129,386 | D002470:Cell Survival; D005456:Fluorescent Dyes; D006367:HeLa Cells; D006801:Humans; D006861:Hydrogen Peroxide; D008928:Mitochondria; D015394:Molecular Structure; D053644:Naphthalimides; D061848:Optical Imaging | Free radical research | 2,018 | D005456:Fluorescent Dyes; D053644:Naphthalimides; D006861:Hydrogen Peroxide |
Subscapularis Z-lengthening in children with brachial plexus birth palsy loses efficiency at mid-term follow-up: a retrospective cohort study. | PURPOSE
The aim of this study was to evaluate early and mid-term clinical outcomes after isolated subscapularis Z-lengthening in children with shoulder internal rotation contractures resulting from brachial plexus birth palsy.
METHODS
Children with brachial plexus birth palsy treated with subscapularis tendon Z-lengt... | 10.1007/s00264-015-3062-6 | 26,649,864 | D001917:Brachial Plexus; D020516:Brachial Plexus Neuropathies; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003286:Contracture; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D016059:Range of Motion, Articular; D012189:Retrospective Studies; D017006:Rotator... | International orthopaedics | 2,016 | |
The expression of a cerebellar degeneration-associated neural antigen in human tumor line cells. | We examined the expression of the paraneoplastic cerebellar degeneration-associated autoantigen (PCD-AA) protein in human tumor lines of different origins by using an immunoaffinity-purified antibody from a patient with paraneoplastic cerebellar degeneration (PCD) and uterine adenocarcinoma. Immunocytochemical studies ... | 10.1212/wnl.42.2.361 | 1,736,166 | D000951:Antigens, Neoplasm; D001324:Autoantigens; D002526:Cerebellar Diseases; D006801:Humans; D015151:Immunoblotting; D007150:Immunohistochemistry; D009419:Nerve Tissue Proteins; D010257:Paraneoplastic Syndromes; D014407:Tumor Cells, Cultured | Neurology | 1,992 | D000951:Antigens, Neoplasm; D001324:Autoantigens; C063762:CDR1 protein, human; D009419:Nerve Tissue Proteins |
A new summarization method for Affymetrix probe level data. | MOTIVATION
We propose a new model-based technique for summarizing high-density oligonucleotide array data at probe level for Affymetrix GeneChips. The new summarization method is based on a factor analysis model for which a Bayesian maximum a posteriori method optimizes the model parameters under the assumption of Gaus... | 10.1093/bioinformatics/btl033 | 16,473,874 | D000465:Algorithms; D003198:Computer Simulation; D015342:DNA Probes; D020869:Gene Expression Profiling; D008957:Models, Genetic; D020411:Oligonucleotide Array Sequence Analysis; D017422:Sequence Analysis, DNA | Bioinformatics (Oxford, England) | 2,006 | D015342:DNA Probes |
Development of a specific PCR assay for the detection of Rhizoctonia solani AG 1-IB using SCAR primers. | AIMS
The aim of this study was to develop a specific and sensitive identification method for Rhizoctonia solani AG 1-IB isolates based on phylogenetic relationships of R. solani AG-1 subgroups using rDNA-internal transcribed spacer (rDNA-ITS) sequence analysis.
METHODS AND RESULTS
A neighbour-joining tree analysis of... | 10.1111/j.1365-2672.2006.03125.x | 17,309,631 | D001483:Base Sequence; D017931:DNA Primers; D004271:DNA, Fungal; D021903:DNA, Ribosomal Spacer; D016533:Mycological Typing Techniques; D010802:Phylogeny; D010944:Plants; D016133:Polymerase Chain Reaction; D019105:Random Amplified Polymorphic DNA Technique; D012232:Rhizoctonia; D017422:Sequence Analysis, DNA; D012988:So... | Journal of applied microbiology | 2,007 | D017931:DNA Primers; D004271:DNA, Fungal; D021903:DNA, Ribosomal Spacer |
Introduction of respiratory pattern generators into models of respiratory control. | We have adapted two models previously proposed as respiratory pattern generators (RPGs) into a neurochemical feed back control model of ventilation. The RPG models, non-dimensional as originally presented, consisted of oscillating circuits of either two or five interconnected neurons [Matsugu, M., Duffin, J., Poon, C.-... | 10.1016/j.resp.2005.02.005 | 16,143,285 | D000222:Adaptation, Physiological; D000818:Animals; D001683:Biological Clocks; D003198:Computer Simulation; D004328:Drive; D008959:Models, Neurological; D016571:Neural Networks, Computer; D009474:Neurons; D010507:Periodicity; D012123:Pulmonary Ventilation; D015656:Respiratory Mechanics | Respiratory physiology & neurobiology | 2,005 | |
Direct and Delayed Dynamics in Electron-Induced Surface Reaction. | The electron-induced reaction of physisorbed vinyl bromide (ViBr) and allyl bromide (AllBr) on Cu(110) at 4.6 K was studied experimentally by scanning tunneling microscopy and theoretically by molecular dynamics. ViBr and AllBr were found to react by two pathways: "Direct", in which the molecule reacted under the tip, ... | 10.1021/jacs.7b07607 | 29,116,796 | Journal of the American Chemical Society | 2,017 | ||
A comparative pilot study on ultraviolet-induced skin changes assessed by noninvasive imaging techniques in vivo. | The effects of acute and chronic ultraviolet (UV) on the morphology of human skin have been extensively studied ex vivo by means of histological investigations. However, innovative skin imaging techniques enable visualization of micromorphological structures in vivo. We aimed to perform a correlation study evaluating i... | 10.1562/2005-12-21-RA-757 | 16,555,922 | D000328:Adult; D003124:Colorimetry; D005260:Female; D006801:Humans; D008297:Male; D018613:Microscopy, Confocal; D010865:Pilot Projects; D012867:Skin; D041623:Tomography, Optical Coherence; D014466:Ultraviolet Rays | Photochemistry and photobiology | 2,006 | |
Myeloid-derived suppressor cells-new and exciting players in lung cancer. | Lung cancer (LC) is the leading cause of cancer-related death worldwide due to its late diagnosis and poor outcomes. As has been found for other types of tumors, there is increasing evidence that myeloid-derived suppressor cells (MDSCs) play important roles in the promotion and progression of LC. Here, we briefly intro... | 10.1186/s13045-020-0843-1 | 32,005,273 | D000818:Animals; D006801:Humans; D007108:Immune Tolerance; D008175:Lung Neoplasms; D000072737:Myeloid-Derived Suppressor Cells; D019139:Tumor Escape; D059016:Tumor Microenvironment | Journal of hematology & oncology | 2,020 | |
Establishment of a Canine Training Model for Digestive Tract Reconstruction after Pancreaticoduodenectomy. | PURPOSE
Practical training models can be a viable and effective educational tool that allows surgeons to acquire specific surgical techniques or skills. However, a suitable animal training model for reconstruction after a pancreaticoduodenectomy (PD) has not yet been reported. Therefore, we explored the feasibility and... | 10.1080/08941939.2019.1663376 | 31,588,822 | D000714:Anastomosis, Surgical; D000818:Animals; D004285:Dogs; D006801:Humans; D007583:Jejunum; D010179:Pancreas; D016577:Pancreaticoduodenectomy; D010193:Pancreaticojejunostomy; D011183:Postoperative Complications | Journal of investigative surgery : the official journal of the Academy of Surgical Research | 2,021 | |
Anti-NMDA receptor encephalitis presenting as isolated aphasia in an adult. | Anti-NMDA receptor (NMDA-r) encephalitis is a relatively rare cause of autoimmune encephalitis with divergent clinical presentations. We report a case of an adult patient with anti-NMDA-r encephalitis presenting with isolated, abrupt-onset aphasia. Her condition remained unaltered over a period of 6 months. The patient... | 10.1080/13554794.2018.1524915 | 30,293,488 | D000328:Adult; D060426:Anti-N-Methyl-D-Aspartate Receptor Encephalitis; D001037:Aphasia; D001921:Brain; D004569:Electroencephalography; D005260:Female; D006801:Humans; D009483:Neuropsychological Tests | Neurocase | 2,018 | |
[Distemper of carnivore: Proliferative activity of lymphocytes in sick and vaccinated dogs]. | Effect of inoculation with canine distemper virus (CDV) strains of various virulence or vaccination with commercial polyvalent preparations on the immune status of puppies has been studied. Serum interferon concentration did not change, irrespective of the strain appurtenance of CDV, while the concentration of tumor ne... | 10,665,060 | D000818:Animals; D004216:Distemper; D004217:Distemper Virus, Canine; D004285:Dogs; D008213:Lymphocyte Activation; D008214:Lymphocytes; D014765:Viral Vaccines | Voprosy virusologii | 1,999 | D014765:Viral Vaccines | |
Factors influencing the duration of late first and second-trimester termination of pregnancy with prostaglandin derivates. | OBJECTIVE
To examine the time interval between first induction and fetal expulsion in fetal defect-related termination of pregnancy and to determine the relevant factors that influence this time interval.
STUDY DESIGN
Retrospective study involving singleton pregnancies that were terminated due to fetal abnormalities ... | 10.1016/j.ejogrb.2010.10.019 | 21,112,135 | D000020:Abortifacient Agents, Nonsteroidal; D000028:Abortion, Induced; D000328:Adult; D000527:Alprostadil; D015232:Dinoprostone; D005260:Female; D005333:Fetus; D005865:Gestational Age; D006801:Humans; D016595:Misoprostol; D010298:Parity; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester... | European journal of obstetrics, gynecology, and reproductive biology | 2,011 | D000020:Abortifacient Agents, Nonsteroidal; D011465:Prostaglandins, Synthetic; D016595:Misoprostol; C021182:gemeprost; D000527:Alprostadil; D015232:Dinoprostone |
Instrument for in situ synchronous measurement of the multi-angle volume scattering function and attenuation coefficient. | An instrument named as Volume Scattering and Attenuation Meter (VSAM) is presented. The VSAM can simultaneously measure the attenuation coefficient and the volume scattering function (VSF) from 10° to 170° with an interval of 10° at 659 nm. Using ultrapure water and NCRM-traceable polystyrene microsphere beads, the VSA... | 10.1364/OE.477129 | 36,606,964 | Optics express | 2,023 | ||
Sitting postural control affects the development of focused attention in children with cerebral palsy. | PURPOSE
To investigate whether focused attention (FA) changes over time as sitting postural control improves and whether an impairment in sitting postural control affects the development of FA in children with cerebral palsy (CP).
METHODS
Nineteen children with CP, mean ages 21.47 months, were assessed for FA and sit... | 10.1097/PEP.0000000000000097 | 25,401,455 | D001288:Attention; D002547:Cerebral Palsy; D002657:Child Development; D002675:Child, Preschool; D003071:Cognition; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009048:Motor Skills; D026741:Physical Therapy Modalities; D004856:Postural Balance; D011187:Posture; D013997:Time Factors | Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association | 2,015 | |
Triglyceride-Glucose Index is Related to Carotid Artery Plaque in Railway Workers: A Cross-Sectional Study. | Aim
China has the highest rail transportation density in the world. Compared to other occupational populations, railway workers in China face increased risk of chronic non-communicable diseases. This study aims to investigate the relationship between the triglyceride-glucose (TyG) index and carotid artery plaque (CAP) ... | 10.2147/DMSO.S418358 | 37,645,236 | Diabetes, metabolic syndrome and obesity : targets and therapy | 2,023 | ||
Online collaborative learning and cognitive presence in mathematics and science education. Case study of university of Rwanda, college of education. | This study aims to investigate how online collaboration can support the learning of science, technology, engineering, and mathematics (STEM) in higher education. Empirical data were collected from 88 postgraduate students studying at the African Centre of Excellence for Innovative Teaching Learning Mathematics and Scie... | 10.1007/s10639-023-11607-w | 36,779,197 | Education and information technologies | 2,023 | ||
Impaired FEF25-75 values may predict bronchial reversibility in allergic children with rhinitis or asthma. | FEV1 is considered an important parameter for asthma diagnosis and follow-up. However, it has been proposed that FEF25-75 could be more sensitive than FEV1 to detect slight airways obstruction. Bronchial reversibility defined by positive response to bronchodilation test. The aim of the present study was to define wheth... | 22,691,246 | D000293:Adolescent; D001249:Asthma; D001980:Bronchi; D002648:Child; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008450:Maximal Midexpiratory Flow Rate; D065631:Rhinitis, Allergic; D012221:Rhinitis, Allergic, Perennial | Journal of biological regulators and homeostatic agents | 2,012 | ||
Analysis of the phospholipid profile of metaphase II mouse oocytes undergoing vitrification. | Oocyte freezing confers thermal and chemical stress upon the oolemma and various other intracellular structures due to the formation of ice crystals. The lipid profiles of oocytes and embryos are closely associated with both, the degrees of their membrane fluidity, as well as the degree of chilling and freezing injurie... | 10.1371/journal.pone.0102620 | 25,033,391 | D000818:Animals; D015925:Cryopreservation; D005260:Female; D008677:Metaphase; D051379:Mice; D008813:Mice, Inbred ICR; D054315:Oocyte Retrieval; D009865:Oocytes; D010743:Phospholipids; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D058989:Vitrification | PloS one | 2,014 | D010743:Phospholipids |
In vivo reversible regulation of dendritic patterning by afferent input in bipolar auditory neurons. | Afferent input regulates neuronal dendritic patterning locally and globally through distinct mechanisms. To begin to understand these mechanisms, we differentially manipulate afferent input in vivo and assess effects on dendritic patterning of individual neurons in chicken nucleus laminaris (NL). Dendrites of NL neuron... | 10.1523/JNEUROSCI.1737-12.2012 | 22,895,732 | D000161:Acoustic Stimulation; D000704:Analysis of Variance; D000818:Animals; D000831:Animals, Newborn; D001306:Auditory Pathways; D001933:Brain Stem; D016923:Cell Death; D002645:Chickens; D003712:Dendrites; D003911:Dextrans; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D021621:Imaging, Three-Dimensi... | The Journal of neuroscience : the official journal of the Society for Neuroscience | 2,012 | D003911:Dextrans; C489787:MAP2 protein, rat; D008869:Microtubule-Associated Proteins; D026941:Sodium Channel Blockers; D013779:Tetrodotoxin |
Is a verification phase needed to determine [Formula: see text]O2max across fitness levels? | INTRODUCTION
Current methods (plateau/secondary criteria) to determine maximal oxygen consumption ([Formula: see text]O2max) are inconsistently achieved leading some to suggest the use of a verification phase (VP) to confirm [Formula: see text]O2max.
PURPOSE
To provide further evidence for the inclusion of a VP to co... | 10.1007/s00421-020-04559-3 | 33,386,984 | D000222:Adaptation, Physiological; D000328:Adult; D015444:Exercise; D005080:Exercise Test; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D010101:Oxygen Consumption; D055815:Young Adult | European journal of applied physiology | 2,021 | |
Endosomal-Escape Polymers Based on Multicomponent Reaction-Synthesized Monomers Integrating Alkyl and Imidazolyl Moieties for Efficient Gene Delivery. | As one of the toughest tasks in the course of intracellular therapeutics delivery, endosomal escape must be effectively achieved, particularly for intracellular gene transport. In this report, novel endosomal-escape polymers were designed and synthesized from monomers by integrating alkyl and imidazolyl via Passerini r... | 10.1021/acsmacrolett.5b00615 | 35,614,816 | ACS macro letters | 2,015 | ||
Influence of the complete basis set approximation, tight weighted-core, and diffuse functions on the DLPNO-CCSD(T1) atomization energies of neutral H,C,O-compounds. | The impact of complete basis set extrapolation schemes (CBS), diffuse functions, and tight weighted-core functions on enthalpies of formation predicted via the DLPNO-CCSD(T1) reduced Feller-Peterson-Dixon approach has been examined for neutral H,C,O-compounds. All tested three-point (TZ/QZ/5Z) extrapolation schemes res... | 10.1002/jcc.27033 | 36,399,072 | D055585:Physical Phenomena | Journal of computational chemistry | 2,023 | |
Keeping the lid on: a century of drug regulation and control. | Since the early 1900s, national and international drug control legislation has acted as a key site of contention between important societal actors. Physicians and pharmacists, regulators and drug companies, patients and addicts, and researchers and pharmacologists all attempted to influence formulation and interpretati... | 10.1016/s0376-8716(03)00096-6 | 12,759,194 | D004345:Drug Industry; D004335:Drug and Narcotic Control; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007391:International Cooperation; D007880:Legislation, Drug; D009294:Narcotics; D011050:Policy Making; D011619:Psychotropic Drugs; D014481:United States | Drug and alcohol dependence | 2,003 | D009294:Narcotics; D011619:Psychotropic Drugs |
RNA extraction from archival formalin-fixed paraffin-embedded tissue: a comparison of manual, semiautomated, and fully automated purification methods. | BACKGROUND
Formalin-fixed paraffin-embedded (FFPE) tumor material represents a valuable resource for the analysis of RNA-based biomarkers, both in research laboratories and in routine clinical testing. A robust and automated RNA-extraction method with a high sample throughput is required.
METHODS
We evaluated extract... | 10.1373/clinchem.2008.122572 | 19,617,290 | D001331:Automation; D014408:Biomarkers, Tumor; D001943:Breast Neoplasms; D005557:Formaldehyde; D015870:Gene Expression; D005821:Genetic Techniques; D006801:Humans; D016612:Paraffin Embedding; D012313:RNA; D015203:Reproducibility of Results; D013997:Time Factors; D016707:Tissue Fixation | Clinical chemistry | 2,009 | D014408:Biomarkers, Tumor; D005557:Formaldehyde; D012313:RNA |
Antiurolithiatic activity of saponin rich fraction from the fruits of Solanum xanthocarpum Schrad. & Wendl. (Solanaceae) against ethylene glycol induced urolithiasis in rats. | ETHNOPHARMACOLOGICAL RELEVANCE
A well-known traditional herb Solanum xanthocarpum is widely used in India for the management of different ailments including urolithiasis. This study was designed to rationalize the use of Solanum xanthocarpum in kidney stone and to investigate its mechanism of action.
MATERIALS AND ME... | 22,981,722 | D000818:Animals; D002129:Calcium Oxalate; D003460:Crystallization; D004195:Disease Models, Animal; D019855:Ethylene Glycol; D005260:Female; D005638:Fruit; D008297:Male; D008517:Phytotherapy; D010936:Plant Extracts; D051381:Rats; D017208:Rats, Wistar; D012503:Saponins; D032322:Solanum; D023382:Toxicity Tests, Acute; D05... | Journal of ethnopharmacology | 2,012 | D010936:Plant Extracts; D012503:Saponins; D002129:Calcium Oxalate; D019855:Ethylene Glycol | |
Association of magnetic resonance imaging phenotypes and serum biomarker levels with treatment response and long-term disease outcomes in multiple sclerosis patients. | BACKGROUND AND PURPOSE
The aim was to evaluate whether magnetic resonance imaging (MRI) phenotypes defined by inflammation and neurodegeneration markers correlate with serum levels of neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) in relapsing-remitting multiple sclerosis (RRMS) patients; an... | 10.1111/ene.16077 | 37,754,568 | European journal of neurology | 2,024 | ||
Electricity system based on 100% renewable energy for India and SAARC. | The developing region of SAARC (South Asian Association for Regional Cooperation) is home to a large number of people living below the poverty line. In future, providing affordable, universally accessible, reliable, low to zero carbon electricity in this region will be the main aim. A cost optimal 100% renewable energy... | 10.1371/journal.pone.0180611 | 28,723,937 | D003247:Conservation of Natural Resources; D004560:Electricity; D007194:India; D059205:Renewable Energy | PloS one | 2,017 | |
Calpain 2 knockdown promotes cell apoptosis and restores gefitinib sensitivity through epidermal growth factor receptor/protein kinase B/survivin signaling. | Gefitinib, an epidermal growth factor receptor (EGFR)‑specific drug, is effective for ~1 year, after which resistance is inevitable. Calpain 2 (CAPN2) is known to serve a role in the drug response and resistance in certain cancer therapies. However, the full function of CAPN2, particularly in non‑small cell lung cancer... | 10.3892/or.2018.6625 | 30,106,446 | D000818:Animals; D017209:Apoptosis; D014408:Biomarkers, Tumor; D002154:Calpain; D002289:Carcinoma, Non-Small-Cell Lung; D002453:Cell Cycle; D002465:Cell Movement; D049109:Cell Proliferation; D019008:Drug Resistance, Neoplasm; D066246:ErbB Receptors; D000077156:Gefitinib; D006801:Humans; D051034:Inhibitor of Apoptosis P... | Oncology reports | 2,018 | C107489:BIRC5 protein, human; D014408:Biomarkers, Tumor; D051034:Inhibitor of Apoptosis Proteins; D047428:Protein Kinase Inhibitors; D011799:Quinazolines; D000077022:Survivin; C512478:EGFR protein, human; D066246:ErbB Receptors; D051057:Proto-Oncogene Proteins c-akt; D002154:Calpain; C569870:CAPN2 protein, human; D0000... |
Zoledronic acid versus alendronate for the prevention of bone loss after heart or liver transplantation. | CONTEXT
The first year after transplantation is characterized by rapid bone loss.
OBJECTIVE
The aim of this study was to compare zoledronic acid (zoledronate) and alendronate for prevention of transplantation bone loss.
DESIGN AND SETTING
A randomized clinical trial was conducted at a transplantation center.
PATI... | 10.1210/jc.2012-2804 | 23,024,190 | D000328:Adult; D019386:Alendronate; D000465:Algorithms; D015519:Bone Density; D050071:Bone Density Conservation Agents; D001862:Bone Resorption; D004164:Diphosphonates; D004311:Double-Blind Method; D005260:Female; D016027:Heart Transplantation; D006801:Humans; D007093:Imidazoles; D016031:Liver Transplantation; D008297:... | The Journal of clinical endocrinology and metabolism | 2,012 | D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D007093:Imidazoles; D010919:Placebos; D000077211:Zoledronic Acid; D019386:Alendronate |
Spectrofluorimetric determination of cisatracurium and mivacurium in spiked human serum and pharmaceuticals. | Spectrofluorimetric methods to determine cisatracurium and mivacurium are proposed and applied to the determination of both substances in human serum and to the determination of mivacurium in pharmaceuticals. The fluorimetric methods allow the determination of 5-500 ng ml(-1) of mivacurium in aqueous solutions and 5-50... | 18,967,664 | Talanta | 1,999 | |||
Postoperative monitoring of the electrical properties of tissue and electrodes in deep brain stimulation. | The aim of this study was to investigate the causation of an insufficient clinical response to acute external stimulation after implantation of brain stimulating electrodes in patients with idiopathic Parkinson's disease (IPD). This study represents to our knowledge the first consecutive postoperative monitoring of the... | 10.1046/j.1525-1403.2003.03032.x | 22,151,071 | Neuromodulation : journal of the International Neuromodulation Society | 2,003 | ||
An electric generator using living Torpedo electric organs controlled by fluid pressure-based alternative nervous systems. | Direct electric power generation using biological functions have become a research focus due to their low cost and cleanliness. Unlike major approaches using glucose fuels or microbial fuel cells (MFCs), we present a generation method with intrinsically high energy conversion efficiency and generation with arbitrary ti... | 10.1038/srep25899 | 27,241,817 | D000109:Acetylcholine; D000818:Animals; D001674:Bioelectric Energy Sources; D004557:Electric Organ; D009424:Nervous System Physiological Phenomena; D014101:Torpedo | Scientific reports | 2,016 | D000109:Acetylcholine |
Label-free identification of Erythropoietin isoforms by surface enhanced Raman spectroscopy. | We present a sensitive label-free surface enhanced Raman spectroscopy (SERS) method for the discrimination between the recombinant and endogenous human Erythropoietin (EPO) isoforms. The proposed methodology comprises a lectin-functionalised extractor chip for the extraction of the recombinant human EPO (rhuEPO) and th... | 10.1016/j.talanta.2021.122879 | 34,635,259 | D004921:Erythropoietin; D006801:Humans; D020033:Protein Isoforms; D011994:Recombinant Proteins; D015203:Reproducibility of Results; D013059:Spectrum Analysis, Raman | Talanta | 2,022 | D020033:Protein Isoforms; D011994:Recombinant Proteins; D004921:Erythropoietin |
[Cerebrospinal fluid dynamics in chronic obstructive hydrocephalus before and after successful endoscopic third ventriculostomy]. | OBJECTIVE
to describe cerebrospinal fluid dynamics in chronic obstructive hydrocephalus before and after successful endoscopic third ventriculostomy (ETV).
MATERIALS AND METHODS
8 patients (7-21 years old) with chronic obstructive hydrocephalus due to tectal plate glioma were investigated before and after successful ... | 19,230,478 | D000293:Adolescent; D002648:Child; D002908:Chronic Disease; D005260:Female; D006801:Humans; D006849:Hydrocephalus; D007427:Intracranial Pressure; D007700:Kinetics; D008297:Male; D044583:Neuroendoscopy; D011187:Posture; D020542:Third Ventricle; D016896:Treatment Outcome; D014696:Ventriculostomy; D055815:Young Adult | Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko | 2,008 | ||
Endotoxin, interleukin-1, and tumor necrosis factor cause neutrophil-dependent microvascular leakage in postcapillary venules. | Acute inflammation is characterized mainly by the egress of neutrophils from postcapillary venules and by increased vascular permeability leading to the formation of edema. The microvascular site of increased vascular permeability in local acute inflammatory lesions was investigated after the injection of endotoxin (LP... | 1,546,745 | D000818:Animals; D002199:Capillary Permeability; D004731:Endotoxins; D007375:Interleukin-1; D008070:Lipopolysaccharides; D008297:Male; D009503:Neutropenia; D009504:Neutrophils; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D012485:Salmonella typhi; D014409:Tumor Necrosis Factor-alpha; D014699:Ve... | The American journal of pathology | 1,992 | D004731:Endotoxins; D007375:Interleukin-1; D008070:Lipopolysaccharides; D014409:Tumor Necrosis Factor-alpha | |
Alignment-Supervised Bidimensional Attention-Based Recursive Autoencoders for Bilingual Phrase Representation. | Exploiting semantic interactions between the source and target linguistic items at different levels of granularity is crucial for generating compact vector representations for bilingual phrases. To achieve this, we propose alignment-supervised bidimensional attention-based recursive autoencoders (ABattRAE) in this pape... | 10.1109/TCYB.2018.2868982 | 30,273,171 | IEEE transactions on cybernetics | 2,020 | ||
[Allapinin pharmacokinetics after its single intravenous administration]. | Allapinin after i.v. bolus infusion in a dose of 30 mg is relatively quickly eliminated from blood (in patients without congestive heart failure half-elimination period is 2.4 +/- 0.5 h and clearance is 79.0 +/- 8.9 l/h) which makes a good reason for its intravenous infusion according to the scheme "load dose + drop in... | 2,663,028 | D000157:Aconitine; D031841:Aconitum; D000328:Adult; D000368:Aged; D002986:Clinical Trials as Topic; D005260:Female; D006207:Half-Life; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction; D014693:Ventricular Fibrillation | Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR | 1,989 | C051402:allapinin; D000157:Aconitine | |
Intraspecific variability of the saccular and utricular otoliths of the hatchetfish Argyropelecus hemigymnus (Cocco, 1829) from the Strait of Messina (Central Mediterranean Sea). | Mesopelagic species are enjoining increasing attention due to the growing impact of fisheries activities on deep marine biocenosis. Improving the knowledge base on mesopelagic species is required to enhance their conservation due to the knowledge gaps regarding many species and families. In this context, otoliths can b... | 10.1371/journal.pone.0281621 | 36,787,328 | D006801:Humans; D000818:Animals; D010037:Otolithic Membrane; D008522:Mediterranean Sea; D005399:Fishes; D005398:Fisheries | PloS one | 2,023 | |
Proteomic analysis of differently expressed proteins in human hepatocellular carcinoma cell lines HepG2 with transfecting hepatitis B virus X gene. | BACKGROUND
Hepatitis B virus encoded X protein (HBx) is a trans-activating protein that may be involved in hepatocarcinogenesis, although few natural effectors of HBx that participate in this process have been identified. We screened, by comparative proteomics method, effectors of HBx associated with hepatocarcinogenes... | 10.3901/jme.2009.12.015 | 19,187,611 | D015153:Blotting, Western; D006528:Carcinoma, Hepatocellular; D045744:Cell Line, Tumor; D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D016133:Polymerase Chain Reaction; D040901:Proteomics; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D015534:Trans-Activators; D054334:Viral R... | Chinese medical journal | 2,009 | D015534:Trans-Activators; D054334:Viral Regulatory and Accessory Proteins; C057628:hepatitis B virus X protein |
Characterization of proteoglycans synthesized by a rat parathyroid cell line. | The structure, biosynthesis, and distribution of cell-associated proteoglycans in a clonal line of parathyroid cells, which exhibit differentiated characteristics such as calcium-regulated hormone secretion and cell growth, were studied by metabolic labeling with [3H] glucosamine and [35S]sulfate as precursors. Proteog... | 2,768,284 | D000818:Animals; D002118:Calcium; D002460:Cell Line; D002499:Centrifugation, Density Gradient; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D002999:Clone Cells; D005944:Glucosamine; D006025:Glycosaminoglycans; D007700:Kinetics; D009844:Oligosaccharides; D010280:Parathyroid Glands; D011509:Proteogl... | The Journal of biological chemistry | 1,989 | D006025:Glycosaminoglycans; D009844:Oligosaccharides; D011509:Proteoglycans; D013431:Sulfates; D013462:Sulfur Radioisotopes; D014316:Tritium; D005944:Glucosamine; D002118:Calcium | |
Internet-based questionnaire assessment: appropriate use in clinical contexts. | Use of internet-mediated questionnaire assessment is growing in behavioural telehealth provision. Literature on web-based psychological testing indicates that--while tests used online should be validated for online use--such measures can be reliable and valid. However, use of normative data (especially data from paper-... | 10.1080/16506070310000957 | 16,291,542 | Cognitive behaviour therapy | 2,003 | ||
Neonatal intermittent hypoxia induces persistent alteration of baroreflex in adult male rats. | Baroreflex is involved in the regulation of arterial blood pressure (BP). An increase in BP activates vagal inhibitory pathways to decrease heart rate; a concomitant decrease in sympathetic discharge reduces vascular resistance. Both responses reduce BP towards normal value. Conversely, a decrease in BP produces opposi... | 10.1007/978-94-007-4584-1_25 | 23,080,160 | D000818:Animals; D000831:Animals, Newborn; D017704:Baroreflex; D001794:Blood Pressure; D006339:Heart Rate; D000860:Hypoxia; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley | Advances in experimental medicine and biology | 2,012 | |
Clinical scores to predict recurrence risk of venous thromboembolism. | Venous thromboembolism (VTE) is a common and chronic disease with a considerable risk of recurrence. Patients with unprovoked (in the absence of a transient risk factor) VTE have a recurrence risk as high as 30% within five years after cessation of anticoagulation. Depending on patient selection the case-fatality rate ... | 10.1160/TH12-05-0353 | 22,872,143 | D000925:Anticoagulants; D015415:Biomarkers; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products; D006801:Humans; D008297:Male; D008955:Models, Cardiovascular; D012307:Risk Factors; D055502:Secondary Prevention; D019851:Thrombophilia; D054556:Venous Thromboembolism | Thrombosis and haemostasis | 2,012 | D000925:Anticoagulants; D015415:Biomarkers; D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D |
Cellular biology of myomas: interaction of sex steroids with cytokines and growth factors. | Many investigators who have been trying to delineate the pathophysiology of leiomyomata believe in the autocrine-paracrine model of tumor growth,where ovarian hormones act as regulators of gene expression in cells. These affected cells overproduce the stimulatory and fibrogenic cytokines and growth factors to which the... | 10.1016/j.ogc.2005.12.005 | 16,504,805 | D016207:Cytokines; D005260:Female; D012739:Gonadal Steroid Hormones; D006133:Growth Substances; D006801:Humans; D007889:Leiomyoma; D008967:Molecular Biology; D014594:Uterine Neoplasms | Obstetrics and gynecology clinics of North America | 2,006 | D016207:Cytokines; D012739:Gonadal Steroid Hormones; D006133:Growth Substances |
Inhibition of 3 beta-hydroxysteroid-dehydrogenase: an approach for prostate cancer treatment? | Over 80% of clinically manifested prostate cancers respond to androgen withdrawal. Several alternatives to castration have been explored. Since a growth promoting role for androstenedione has been suggested, we investigated the effect of inhibition of 3 beta-hydroxy-steroid-dehydrogenase (3 beta-HSD), a key enzyme invo... | 7,654,020 | D015096:3-Hydroxysteroid Dehydrogenases; D000818:Animals; D001378:Azasteroids; D003687:Dehydroepiandrosterone; D013196:Dihydrotestosterone; D004791:Enzyme Inhibitors; D008297:Male; D011471:Prostatic Neoplasms; D051381:Rats; D013739:Testosterone | Anticancer research | 1,995 | D001378:Azasteroids; D004791:Enzyme Inhibitors; D013196:Dihydrotestosterone; D013739:Testosterone; D003687:Dehydroepiandrosterone; C031563:17-N,N-diethylcarbamoyl-4-methyl-4-azaandrostane-3-one; D015096:3-Hydroxysteroid Dehydrogenases | |
Oxidation of p,p'-DDT and p,p'-DDE in highly and long-term contaminated soil using Fenton reaction in a slurry system. | The degradation of DDT [1,1-bis(4-chlorophenyl)-2,2,2-trichloroethane] and DDE [2,2-bis(4-chlorophenyl)-1,1-dichloroethylene] in highly and long-term contaminated soil using Fenton reaction in a slurry system is studied in this work. The influence of the amount of soluble iron added to the slurry versus the mineral iro... | 10.1016/j.scitotenv.2006.05.010 | 16,782,172 | D003634:DDT; D003633:Dichlorodiphenyl Dichloroethylene; D006861:Hydrogen Peroxide; D006863:Hydrogen-Ion Concentration; D007501:Iron; D008962:Models, Theoretical; D010084:Oxidation-Reduction; D012987:Soil; D012989:Soil Pollutants; D013997:Time Factors | The Science of the total environment | 2,006 | C045076:Fenton's reagent; D012987:Soil; D012989:Soil Pollutants; D003633:Dichlorodiphenyl Dichloroethylene; D006861:Hydrogen Peroxide; D003634:DDT; D007501:Iron |
A serum-free growth of a human hepatoma cell line as a tool for hepatocarcinogenesis and virus gene expression. | The PLC/PRF/5 human hepatoma cells were grown in a serum-free, hormone-free, chemically defined medium; we recently characterized cell growth and hepatitis B surface antigen (HBsAg) production by these cells under these culture conditions, in the absence of interfering substances. Because of the biochemical and the ant... | 2,995,177 | D006528:Carcinoma, Hepatocellular; D002455:Cell Division; D002460:Cell Line; D003470:Culture Media; D003907:Dexamethasone; D005814:Genes, Viral; D006514:Hepatitis B Surface Antigens; D006515:Hepatitis B virus; D006801:Humans; D006854:Hydrocortisone; D007328:Insulin; D008113:Liver Neoplasms | Developments in biological standardization | 1,985 | D003470:Culture Media; D006514:Hepatitis B Surface Antigens; D007328:Insulin; D003907:Dexamethasone; D006854:Hydrocortisone | |
Strong electroweak symmetry breaking and spin-0 resonances. | We argue that theories of the strong electroweak symmetry breaking sector necessarily contain new spin 0 states at the TeV scale in the tt and tb/bt channels, even if the third generation quarks are not composite at the TeV scale. These states couple sufficiently strongly to third generation quarks to have significant ... | 10.1103/PhysRevLett.103.101801 | 19,792,295 | Physical review letters | 2,009 | ||
Rectus femoris muscle injuries in football: a clinically relevant review of mechanisms of injury, risk factors and preventive strategies. | Quadriceps muscle strains frequently occur in sports that require repetitive kicking and sprinting, and are common in football in its different forms around the world. This paper is a review of aetiology, mechanism of injury and the natural history of rectus femoris injury. Investigating the mechanism and risk factors ... | 10.1136/bjsports-2012-091250 | 22,864,009 | D000367:Age Factors; D001265:Athletic Injuries; D001827:Body Height; D001835:Body Weight; D007839:Functional Laterality; D006801:Humans; D007869:Leg Injuries; D008279:Magnetic Resonance Imaging; D053580:Muscle Strength; D052580:Muscle Stretching Exercises; D018583:Pliability; D052097:Quadriceps Muscle; D012307:Risk Fac... | British journal of sports medicine | 2,013 | |
On the formation of phosphorous polycyclic aromatics hydrocarbons (PAPHs) in astrophysical environments. | The formation of phosphorous-containing polycyclic aromatic hydrocarbons (PAPHs) in astrophysical contexts is proposed and analyzed by means of computational methods [B3LYP-D3BJ/ma-def2-TZVPP, MP2-F12, CCSD-F12b and CCSD(T)-F12b levels of theory]. A "bottom-up" approach based on a radical-neutral reaction scheme betwee... | 10.1039/c9cp00547a | 30,931,458 | Physical chemistry chemical physics : PCCP | 2,019 | ||
Purification and properties of rat uterine procollagenase. | A procollagenase from monolayer cultures of postpartum rat uterine cells has been purified. The crucial step in the purification is the binding of the procollagenase from crude, fetal bovine serum-containing culture medium to heparin-Sepharose, followed by elution with extremely low concentrations (5-10 nM) of dextran ... | 10.1016/0003-9861(83)90032-2 | 6,311,106 | D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002845:Chromatography; D017364:Collagenases; D004591:Electrophoresis, Polyacrylamide Gel; D004792:Enzyme Precursors; D005260:Female; D003012:Microbial Collagenase; D008970:Molecular Weight; D051381:Rats; D014599:Uterus | Archives of biochemistry and biophysics | 1,983 | D004792:Enzyme Precursors; D017364:Collagenases; C022440:procollagenase; D003012:Microbial Collagenase |
Multidimensional Comparative Analysis of Bioactive Phenolic Compounds of Honeys of Various Origin. | Honey is a natural product which owes its health benefits to its numerous bioactive compounds. The composition of honey is highly diverse and depends on the type of honey and its origin. Antioxidant capacity arises mainly from the total content of polyphenols and their composition. The aim of this study was to perform ... | 10.3390/antiox10040530 | 33,805,391 | Antioxidants (Basel, Switzerland) | 2,021 | ||
Tool use in a group of captive chimpanzees I. Escape. | A group of 4 female and 3 male adolescent wild-born chimpanzees was observed for 7 months in an outdoor enclosure. Use of tools aimed at escaping from this enclosure is decribed, the two main techniques being the use of poles as ladders and sticks as pitons. | 10.1111/j.1439-0310.1975.tb01133.x | 1,146,425 | D000819:Animal Communication; D000818:Animals; D001522:Behavior, Animal; D004924:Escape Reaction; D005260:Female; D007858:Learning; D008297:Male; D008722:Methods; D002679:Pan troglodytes; D012919:Social Behavior | Zeitschrift fur Tierpsychologie | 1,975 | |
Development of Plant-Based Adipose Tissue Analogs: Freeze-Thaw and Cooking Stability of High Internal Phase Emulsions and Gelled Emulsions. | There is great interest in the development of plant-based alternatives to meat products to meet the rising demand from vegans, vegetarians, and flexitarians. Ideally, these products should look, feel, taste, and behave like the meat products they are designed to replace. In this study, we investigated the impact of sim... | 10.3390/foods11243996 | 36,553,739 | Foods (Basel, Switzerland) | 2,022 | ||
Trends, Characteristics, and Clinical Outcomes of Patients Undergoing Percutaneous Coronary Intervention in Korea between 2011 and 2015. | BACKGROUND AND OBJECTIVES
We sought to evaluate nationwide trends, characteristics, and clinical outcomes in patients undergoing percutaneous coronary intervention (PCI) in Korea.
METHODS
From National Health Insurance claims data in Korea, 81,115 patients, who underwent PCI for the first episode of coronary artery d... | 10.4070/kcj.2017.0359 | 29,625,513 | Korean circulation journal | 2,018 | ||
Directing pluripotent cell differentiation using "diced RNA" in transient transfection. | Embryonic stem (ES) and embryonic carcinoma (EC) cells are pluripotent and have the capacity to differentiate into many cell types. The ability to direct their differentiation should have considerable practical applications. Here, we first report the use of diced short interfering RNAi against Oct4 in a transient appro... | 10.1002/gene.20078 | 15,515,021 | D000818:Animals; D002454:Cell Differentiation; D019070:Cell Lineage; D002478:Cells, Cultured; D004268:DNA-Binding Proteins; D004622:Embryo, Mammalian; D005136:Eye Proteins; D005326:Fetal Proteins; D005786:Gene Expression Regulation; D018398:Homeodomain Proteins; D051379:Mice; D050814:Octamer Transcription Factor-3; D00... | Genesis (New York, N.Y. : 2000) | 2,004 | D004268:DNA-Binding Proteins; D005136:Eye Proteins; D005326:Fetal Proteins; D018398:Homeodomain Proteins; D050814:Octamer Transcription Factor-3; D000071841:PAX6 Transcription Factor; D051761:Paired Box Transcription Factors; C000605732:Pax6 protein, mouse; C494174:Pou5f1 protein, mouse; D012097:Repressor Proteins; D05... |
Changes of Conformation in Albumin with Temperature by Molecular Dynamics Simulations. | This work presents the analysis of the conformation of albumin in the temperature range of 300 K - 312 K , i.e., in the physiological range. Using molecular dynamics simulations, we calculate values of the backbone and dihedral angles for this molecule. We analyze the global dynamic properties of albumin treated as a c... | 10.3390/e22040405 | 33,286,179 | Entropy (Basel, Switzerland) | 2,020 | ||
The state of health and health services in Sudan as a result of the war. | No abstract available. | 10.4102/phcfm.v15i1.4260 | 37,916,714 | D006801:Humans; D013397:Sudan; D014857:Warfare; D006296:Health Services | African journal of primary health care & family medicine | 2,023 | |
The influence of personality, curriculum, and memory correlates on formal reasoning in young adults and elderly persons. | The study examined the effects of age, sex, and curriculum upon the cognitive performance of 20 college students and 20 college-educated elderly individuals. Participants were given a battery of formal operational tasks, a measure of field independence/field dependence, a memory-span measure, and a measure of tolerance... | 10.1093/geronj/39.2.207 | 6,699,377 | D000328:Adult; D000368:Aged; D000375:Aging; D003071:Cognition; D003479:Curriculum; D004522:Educational Status; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory; D008875:Middle Aged; D010551:Personality; D013850:Thinking | Journal of gerontology | 1,984 | |
Nonlinear diffusion and beam self-trapping in diffraction-managed waveguide arrays. | We study nonlinear propagation of light in diffraction-managed photonic lattices created by periodically-curved arrays of optical waveguides. We identify different regimes of the nonlinear propagation of light in such structures depending on the input power. We start from the regime of self-collimation at low powers an... | 10.1364/oe.15.009547 | 19,547,303 | Optics express | 2,007 | ||
Evaluation of rapid antigen detection kits for diagnosis of equine rotavirus infection. | We evaluated antigen detection kits for human rotavirus with regard to their usefulness for diagnosing equine rotavirus infection. Limiting dilution analyses showed that of the seven kits investigated the Dipstick `Eiken' Rota (Dipstick) had the highest sensitivity to two serotypes of equine rotavirus. The Dipstick did... | 10.1292/jvms.10-0064 | 20,453,452 | D000818:Animals; D000956:Antigens, Viral; D005784:Gene Amplification; D005814:Genes, Viral; D006734:Horse Diseases; D006736:Horses; D016133:Polymerase Chain Reaction; D011933:Reagent Kits, Diagnostic; D012401:Rotavirus; D012400:Rotavirus Infections; D012680:Sensitivity and Specificity | The Journal of veterinary medical science | 2,010 | D000956:Antigens, Viral; D011933:Reagent Kits, Diagnostic |
Parent and child distress after war exposure. | OBJECTIVES
The purpose of this study was to examine multiple distress symptoms (i.e., post-traumatic stress [PTS], anxiety, depression) among parents and children exposed to the Gulf Crisis in 1990-1991. Profiles of parent distress were identified, and the relationship between parent distress and specific child distres... | 10.1111/bjc.12049 | 24,702,278 | D000328:Adult; D001007:Anxiety; D002648:Child; D003430:Cross-Sectional Studies; D003863:Depression; D005260:Female; D047830:Gulf War; D006801:Humans; D008297:Male; D010287:Parent-Child Relations; D010290:Parents; D012307:Risk Factors; D013313:Stress Disorders, Post-Traumatic; D013315:Stress, Psychological | The British journal of clinical psychology | 2,014 | |
A neural Wiskott-Aldrich Syndrome protein-mediated pathway for localized activation of actin polymerization that is regulated by cortactin. | Activation of the epidermal growth factor (EGF) receptor can stimulate actin polymerization via the Arp2/3 complex using a number of signaling pathways, and specific stimulation conditions may control which pathways are activated. We have previously shown that localized stimulation of EGF receptor with EGF bound to bea... | 10.1074/jbc.M410713200 | 15,579,908 | D000199:Actins; D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D002417:Cattle; D002460:Cell Line; D002465:Cell Movement; D051356:Cortactin; D003599:Cytoskeleton; D004815:Epidermal Growth Factor; D051380:GRB2 Adaptor Protein; D006801:Humans; D008840:Microfilament Proteins; D009474:Neurons; D015513:Oncoge... | The Journal of biological chemistry | 2,005 | D000199:Actins; D048868:Adaptor Proteins, Signal Transducing; C495868:CTTN protein, human; D051356:Cortactin; C495870:Cttn protein, rat; D051380:GRB2 Adaptor Protein; C495948:GRB2 protein, human; C495950:Grb2 protein, rat; D008840:Microfilament Proteins; C485544:NCK2 protein, human; D015513:Oncogene Proteins; D011506:P... |
Normal relationship of the cervicomedullary junction with the obex and olivary bodies: a comparison of cadaveric dissection and in vivo diffusion tensor imaging. | PURPOSE
The purpose of our study is to compare cadaver dissections with in vivo diffusion tensor imaging (DTI) to determine the position of the cervicomedullary junction (CMJ) relative to the readily identified anatomic landmarks, namely the obex and olivary bodies (olives), in normal subjects. The information gained f... | 10.1007/s00276-014-1387-2 | 25,318,624 | D001921:Brain; D002102:Cadaver; D056324:Diffusion Tensor Imaging; D004210:Dissection; D005260:Female; D006801:Humans; D008297:Male; D011712:Pyramidal Tracts | Surgical and radiologic anatomy : SRA | 2,015 | |
Transmanubrial osteomuscolar sparing approach for T1-T2 thoracic disc herniation. | Herniated thoracic disks are rare entities and their surgical treatment comprises 0.15% to 4% of all disk operations. Surgical approaches have included pediculectomy, costotransversectomy, lateral extracavitary, transthoracic thoracotomy, and thoracoscopy. The authors present a transmanubrial osteomuscular sparing appr... | 18,923,353 | D000368:Aged; D006801:Humans; D007405:Intervertebral Disc Displacement; D008279:Magnetic Resonance Imaging; D008297:Male; D008371:Manubrium; D019635:Neurosurgical Procedures; D019736:Prostheses and Implants; D019919:Prosthesis Implantation; D013904:Thoracic Vertebrae; D014025:Titanium; D014057:Tomography, X-Ray Compute... | Minerva chirurgica | 2,008 | D014025:Titanium | |
[Electron microscopy in the differential diagnosis and prognostic evaluation of muscle tissue tumors]. | The ultrastructure of striated and smooth muscle tumors of man was studied. A set of features indicating the histological origin of these tumors was established. The most informative feature for tumors of both groups is the presence of fragments of specific microfibrillar apparatus. An analysis of the extent of its dev... | 526,164 | D005260:Female; D006801:Humans; D007889:Leiomyoma; D007890:Leiomyosarcoma; D008854:Microscopy, Electron; D009130:Muscle, Smooth; D009131:Muscle, Smooth, Vascular; D009135:Muscular Diseases; D009210:Myofibrils; D012208:Rhabdomyosarcoma; D013274:Stomach Neoplasms; D014594:Uterine Neoplasms | Arkhiv patologii | 1,979 | ||
Deep brain stimulation of the orbitofrontal cortex prevents the development and reinstatement of morphine place preference. | The orbitofrontal cortex (OFC) is involved in compulsive drug seeking and drug relapse. Its involvement in cue-, context-, and stress-induced reinstatement of drug seeking has also been confirmed in animal models. Deep brain stimulation (DBS) was proposed to be an effective intervention for patients with treatment-refr... | 10.1111/adb.12780 | 31,210,397 | D000701:Analgesics, Opioid; D000818:Animals; D001522:Behavior, Animal; D003214:Conditioning, Classical; D046690:Deep Brain Stimulation; D058999:Drug-Seeking Behavior; D005108:Extinction, Psychological; D008297:Male; D009020:Morphine; D009021:Morphine Dependence; D017397:Prefrontal Cortex; D051381:Rats | Addiction biology | 2,020 | D000701:Analgesics, Opioid; D009020:Morphine |
Experiences of persons with lower limb amputation after prosthetic rehabilitation in Ghana: A qualitative inquiry. | BACKGROUND
Lower limb amputations (LLAs) have long been associated with physical, social, and psychological consequences. Individuals with LLAs have challenges with mobility and often become isolated from their social networks. Disability rehabilitation technologies such as prosthetic devices are used to improve the mo... | 10.1097/PXR.0000000000000264 | 37,615,618 | Prosthetics and orthotics international | 2,023 | ||
Using the hazard function to evaluate hepatocellular carcinoma recurrence risk after curative resection. | Predicting recurrence patterns of hepatocellular carcinoma (HCC) can be helpful in developing surveillance strategies. This study aimed to use the hazard function to investigate recurrence hazard and peak recurrence time transitions in patients with HCC undergoing liver resection (LR). We enrolled 1204 patients with HC... | 10.1007/s13304-023-01652-y | 37,903,995 | Updates in surgery | 2,023 | ||
Measuring readiness and motivation to quit smoking among women in public health clinics: predictive validity. | We conducted an independent pilot test of the internal consistency, stability, and predictive validity of the instrument presented by Crittenden, Manfredi, Lacey, Warnecke, and Parsons (1994) using a two-wave panel of female smokers in 12 public health clinics. This instrument subdivides the precontemplation stage prop... | 10.1016/s0306-4603(97)00044-0 | 9,573,423 | D000328:Adult; D001294:Attitude to Health; D016009:Chi-Square Distribution; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D016013:Likelihood Functions; D008137:Longitudinal Studies; D009042:Motivation; D010865:Pilot Projects; D011594:Psychometrics; D015203:Reproducibility of Results; D012647:Self... | Addictive behaviors | 1,998 | |
Spontaneous in contrast to CD95-induced neutrophil apoptosis is independent of caspase activity. | BACKGROUND
The influence of caspase inhibitors on spontaneous and on CD95-triggered apoptosis was investigated in neutrophils from healthy volunteers and compared with neutrophils from patients with severe sepsis.
METHODS
To further elucidate the mechanisms of neutrophil apoptosis, isolated neutrophils from healthy v... | 10.1097/00005373-200106000-00003 | 11,426,111 | D000590:Amino Acid Chloromethyl Ketones; D017209:Apoptosis; D016022:Case-Control Studies; D020169:Caspases; D015853:Cysteine Proteinase Inhibitors; D004789:Enzyme Activation; D006801:Humans; D009504:Neutrophils; D018805:Sepsis; D019014:fas Receptor | The Journal of trauma | 2,001 | D000590:Amino Acid Chloromethyl Ketones; D015853:Cysteine Proteinase Inhibitors; C096713:benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone; D019014:fas Receptor; D020169:Caspases |
Surface receptor-mediated activation of adenylate cyclase in Dictyostelium. Regulation by guanine nucleotides in wild-type cells and aggregation deficient mutants. | GTP and GTP analogs produced significant (up to 17-fold) and persistent activation of adenylate cyclase in lysates of Dictyostelium discoideum amoeba. The activation was enhanced 2- to 4-fold by cAMP (the agonist for receptor-mediated adenylate cyclase activation), was specific for guanine nucleoside triphosphates, and... | 3,771,567 | D020727:ADP-Ribosylation Factors; D000262:Adenylyl Cyclases; D002462:Cell Membrane; D004023:Dictyostelium; D004789:Enzyme Activation; D006150:Guanine Nucleotides; D006165:Guanylyl Imidodiphosphate; D007700:Kinetics; D008565:Membrane Proteins; D009154:Mutation; D010641:Phenotype | The Journal of biological chemistry | 1,986 | D006150:Guanine Nucleotides; D008565:Membrane Proteins; D006165:Guanylyl Imidodiphosphate; D020727:ADP-Ribosylation Factors; D000262:Adenylyl Cyclases | |
Costs and quality-of-life effects of implantable cardioverter-defibrillators. | Although the clinical efficacy of implantable cardioverter-defibrillators (ICDs) has been convincingly demonstrated in clinical trials, the impact of ICDs on health care costs and recipients' quality of life (QOL) is less certain. The existing medical research on the health care costs and QOL effects of ICDs was review... | 10.1016/j.amjcard.2006.06.041 | 17,134,641 | D000203:Activities of Daily Living; D003365:Costs and Cost Analysis; D017147:Defibrillators, Implantable; D006801:Humans; D011788:Quality of Life; D014481:United States | The American journal of cardiology | 2,006 | |
Cellular and molecular mechanisms of pentoxifylline's beneficial effects in experimental polycystic ovary. | Chronic low-grade inflammation and oxidative stress (OS) appear to be two main pathways involved in the pathogenesis of polycystic ovary (PCO) syndrome. Therefore, targeting these pathways by means of anticytokine and antioxidant agents might be a therapeutic alternative approach to the current treatments of PCO syndro... | 25,557,188 | D000818:Animals; D047072:Aromatase Inhibitors; D015415:Biomarkers; D005260:Female; D000077289:Letrozole; D009570:Nitriles; D018384:Oxidative Stress; D010431:Pentoxifylline; D011085:Polycystic Ovary Syndrome; D051381:Rats; D017208:Rats, Wistar; D017382:Reactive Oxygen Species; D014230:Triazoles; D014665:Vasodilator Agen... | Theriogenology | 2,015 | D047072:Aromatase Inhibitors; D015415:Biomarkers; D009570:Nitriles; D017382:Reactive Oxygen Species; D014230:Triazoles; D014665:Vasodilator Agents; D000077289:Letrozole; D010431:Pentoxifylline | |
Microdosemeter instrument (MIDN) for assessing risk in space. | Radiation in space generally produces higher dose rates than that on the Earth's surface, and contributions from primary galactic and solar events increase with altitude within the magnetosphere. Presently, no personnel monitor is available to astronauts for real-time monitoring of dose, radiation quality and regulator... | 10.1093/rpd/ncq525 | 21,199,825 | D040761:Biomimetic Materials; D001822:Body Burden; D003359:Cosmic Radiation; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006801:Humans; D008904:Miniaturization; D011829:Radiation Dosage; D011834:Radiation Monitoring; D012062:Relative Biological Effectiveness; D018570:Risk Assessment; D018531:Spacecra... | Radiation protection dosimetry | 2,011 | |
CHOP-based chemotherapy is as effective as alternating PEEC/CHOP chemotherapy in a randomised trial in high-grade non-Hodgkin's lymphoma. Scotland and Newcastle Lymphoma Group. | The aim of this study was to test whether survival for patients with high-grade non-Hodgkin's lymphoma (NHL) can be improved with a non-cross-resistant regimen as compared to a CHOP-based regimen. This is a multicentre study comprising 325 adult patients, median age 58 years, with high-grade non-Hodgkin's lymphoma: pat... | 10.1016/s0959-8049(97)00051-8 | 9,301,442 | D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols; D001761:Bleomycin; D002699:Chlorambucil; D003520:Cyclophosphamide; D018572:Disease-Free Survival; D004317:Doxorubicin; D004334:Drug Administration Schedule; D005047:Etoposide; D005500:Follow-Up Studies; D006801:Humans; D008228:Lymphoma... | European journal of cancer (Oxford, England : 1990) | 1,997 | D001761:Bleomycin; D002699:Chlorambucil; D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone; D014751:Vindesine; D008775:Methylprednisolone; D008727:Methotrexate |
Sensorimotor interventions improve growth and motor function in preterm infants. | PURPOSE
To assess the effect of an oral (O+O), a tactile/kinesthetic (T/K+T/K), and a combined (O+T/K) intervention on preterm infants' weight gain and motor function and to determine whether the combined O+T/K intervention has an additive/synergistic effect on outcomes.
DESIGN/SAMPLE
Seventy-five preterm infants wer... | 10.1891/0730-0832.29.6.359 | 21,071,361 | D002657:Child Development; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007363:Intensive Care Units, Neonatal; D008297:Male; D008405:Massage; D009055:Mouth; D011597:Psychomotor Performance; D016037:Single-Blind Method; D015430:Weight Gain | Neonatal network : NN | 2,010 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.