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Antimicrobial drug use in a small Indian community hospital. | Antimicrobial drug use and overuse have been a topic of interest for many years, lately focusing on the growing resistance worldwide. This study was conducted in a small Indian hospital, where more than 80% of all admitted patients received antimicrobial drugs. Penicillin, gentamycin, co-trimoxazole, ciprofloxacin and ... | 10.1258/td.2010.090157 | 20,870,677 | D000293:Adolescent; D000328:Adult; D000890:Anti-Infective Agents; D011307:Drug Prescriptions; D004363:Drug Utilization; D005260:Female; D006743:Hospital Bed Capacity, under 100; D016519:Hospitals, Religious; D006801:Humans; D007194:India; D007297:Inpatients; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D0... | Tropical doctor | 2,010 | D000890:Anti-Infective Agents |
In vivo imaging of protease activity by Probody therapeutic activation. | Probody™ therapeutics are recombinant, proteolytically-activated antibody prodrugs, engineered to remain inert until activated locally by tumor-associated proteases. Probody therapeutics exploit the fundamental dysregulation of extracellular protease activity that exists in tumors relative to healthy tissue. Leveraging... | 26,546,838 | D000818:Animals; D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents; D001667:Binding, Competitive; D045744:Cell Line, Tumor; D000068818:Cetuximab; D003952:Diagnostic Imaging; D066246:ErbB Receptors; D005260:Female; D005456:Fluorescent Dyes; D006801:Humans; D008175:Lung Neoplasms; D008819:Mice, Nude; D010447:... | Biochimie | 2,016 | C502599:Alexa Fluor 750; D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents; D005456:Fluorescent Dyes; D011355:Prodrugs; D013388:Succinimides; D066246:ErbB Receptors; D010447:Peptide Hydrolases; D000068818:Cetuximab | |
The multifaceted murine plasmacytoid dendritic cell. | Plasmacytoid dendritic cells (PDCs) or natural interferon-producing cells, function as the body's innate defense against viral infections. As discussed here, they may play additional roles in response to bacterial pathogens and may have the capacity to induce different type of T-cell responses depending on what signals... | 10.1016/s0198-8859(02)00747-4 | 12,480,252 | D000818:Animals; D000943:Antigens, Differentiation; D001327:Autoimmune Diseases; D003713:Dendritic Cells; D005786:Gene Expression Regulation; D007108:Immune Tolerance; D016898:Interferon-alpha; D051379:Mice; D009369:Neoplasms | Human immunology | 2,002 | D000943:Antigens, Differentiation; D016898:Interferon-alpha |
CD8 naive T cell counts decrease progressively in HIV-infected adults. | We show here that CD8 naive T cells are depleted during the asymptomatic stage of HIV infection. Although overall CD8 T cell numbers are increased during this stage, the naive CD8 T cells are progressively lost and fall in parallel with overall CD4 T cell counts. In addition, we show that naive CD4 T cells are preferen... | 10.1172/JCI117892 | 7,738,173 | D000328:Adult; D015703:Antigens, CD; D018791:CD4 Lymphocyte Count; D015496:CD4-Positive T-Lymphocytes; D018414:CD8-Positive T-Lymphocytes; D018450:Disease Progression; D005434:Flow Cytometry; D015658:HIV Infections; D006801:Humans; D018655:Lymphocyte Count; D016176:T-Lymphocyte Subsets | The Journal of clinical investigation | 1,995 | D015703:Antigens, CD |
On the Concept of Praecox Feeling. | Despite the development and widespread diffusion of modern nosographic systems, the diagnosis of schizophrenia continues to raise several epistemological issues. To address these issues, a number of researchers are currently pursuing the possibility of an integration between reliable, objective approaches and the inter... | 10.1159/000494088 | 30,380,532 | D005260:Female; D006801:Humans; D008297:Male; D011599:Psychopathology; D012559:Schizophrenia | Psychopathology | 2,018 | |
The isolation of prothrombin, Factor IX and Factor X from human Factor IX concentrates. | A relatively simple and reproducible procedure is described for the isolation of functionally and electrophoretically homogeneous prothrombin, factor IX and factor X from clinical Factor IX Concentrates. The procedure involves ammonium sulphate fractionation; then chromatography on DEAE-Sephadex A50, dextran sulphate-S... | 10.1016/0049-3848(84)90193-2 | 6,084,874 | D002847:Chromatography, Agarose; D002852:Chromatography, Ion Exchange; D016264:Dextran Sulfate; D003911:Dextrans; D005164:Factor IX; D005170:Factor X; D006801:Humans; D011516:Prothrombin; D012685:Sepharose | Thrombosis research | 1,984 | D003911:Dextrans; C037405:heparin-sepharose; D011516:Prothrombin; D005164:Factor IX; D005170:Factor X; D012685:Sepharose; D016264:Dextran Sulfate |
Poly(ADP-ribose) biosynthesis and suicidal NAD+ depletion following carcinogen exposure of mammalian cells. | Hepatocytes were found to be remarkably resistant to suicidal NAD+ depletion due to consumption for chromatin-associated poly(ADP-ribose) biosynthesis, which normally follows infliction of DNA damage in mammalian cells. N-methyl-N'-nitro-N-nitrosoguanidine treatment, which depleted NAD+ levels of confluent fibroblasts ... | 10.1016/s0006-291x(86)80388-6 | 3,753,486 | D000818:Animals; D001549:Benzamides; D002273:Carcinogens; D002460:Cell Line; D002478:Cells, Cultured; D004260:DNA Repair; D008099:Liver; D008769:Methylnitronitrosoguanidine; D051379:Mice; D009243:NAD; D009702:Nucleoside Diphosphate Sugars; D011064:Poly Adenosine Diphosphate Ribose; D051381:Rats; D013463:Sulfuric Acid E... | Biochemical and biophysical research communications | 1,986 | D001549:Benzamides; D002273:Carcinogens; D009702:Nucleoside Diphosphate Sugars; D013463:Sulfuric Acid Esters; D009243:NAD; D008769:Methylnitronitrosoguanidine; D011064:Poly Adenosine Diphosphate Ribose; C025160:3-aminobenzamide; C007482:dimethyl sulfate |
Cost-effectiveness of augmenting universal hepatitis B vaccination with immunoglobin treatment. | OBJECTIVE
To compare the cost-effectiveness of hepatitis B virus (HBV) control strategies combining universal vaccination with hepatitis B immunoglobulin (HBIG) treatment for neonates of carrier mothers.
METHODS
Drawing on Taiwan's experience, we developed a decision-analytic model to estimate the clinical and econom... | 10.1542/peds.2012-1262 | 23,530,168 | D015415:Biomarkers; D002353:Carrier State; D003362:Cost-Benefit Analysis; D003661:Decision Support Techniques; D003663:Decision Trees; D003906:Developing Countries; D005260:Female; D006509:Hepatitis B; D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines; D006513:Hepatitis B e Antigens; D006801:Humans; D0... | Pediatrics | 2,013 | D015415:Biomarkers; D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines; D006513:Hepatitis B e Antigens; D007136:Immunoglobulins; D007155:Immunologic Factors; C045213:hepatitis B hyperimmune globulin |
Arginine metabolism and the role of arginine deiminase-producing microorganisms in kimchi fermentation. | In this study, we evaluated the correlation between the arginine deiminase (ADI) pathway and nitrogen cycle during cabbage kimchi fermentation. Nitrite used as a food additive can be converted to carcinogenic N-nitroso compounds via reactions with secondary amines under specific conditions; thus, high nitrate- and nitr... | 10.1016/j.heliyon.2022.e11802 | 36,458,308 | Heliyon | 2,022 | ||
The effect of posterior hypothalamus region deep brain stimulation on sleep. | BACKGROUND
Early observations by von Economo showed that the posterior part of the hypothalamus (PH) plays a prominent role in sleep-wake regulation. The PH is a candidate area involved in cluster headaches and other trigeminal autonomic cephalalgias (TACs) and is targeted for deep brain stimulation (DBS).
CASE REPOR... | 10.1177/0333102413505241 | 24,045,569 | D000328:Adult; D000368:Aged; D003027:Cluster Headache; D046690:Deep Brain Stimulation; D006801:Humans; D007031:Hypothalamus; D008297:Male; D050798:SUNCT Syndrome; D012890:Sleep; D012893:Sleep Wake Disorders; D016896:Treatment Outcome | Cephalalgia : an international journal of headache | 2,014 | |
Distribution of marbofloxacin in the bronchoalveolar region in healthy calves. | The purpose of this study was to clarify the distribution of marbofloxacin (MBFX) within the bronchoalveolar region of calves. Four clinically healthy calves were intramuscularly injected with a single dose of MBFX (2 mg/kg). Samples of plasma and bronchoalveolar lavage fluid (BALF) were obtained for each calf at 0 (be... | 10.1292/jvms.18-0761 | 30,918,227 | D056809:Alveolar Epithelial Cells; D000818:Animals; D000900:Anti-Bacterial Agents; D001992:Bronchoalveolar Lavage Fluid; D002417:Cattle; D024841:Fluoroquinolones; D007273:Injections, Intramuscular; D008297:Male | The Journal of veterinary medical science | 2,019 | D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; C080260:marbofloxacin |
The synchronization of recruitment-based activities in ants. | A simple model of recruitment-based foraging in ants illustrates the idea that synchronized patterns of activity can endow a colony with the ability to forage more efficiently when a minimal number of active individuals is required to establish and maintain food source exploitation. This model, which can be extended to... | 10.1016/s0303-2647(98)00004-5 | 9,648,665 | D000818:Animals; D001000:Ants; D001070:Appetitive Behavior; D008954:Models, Biological; D013647:Task Performance and Analysis | Bio Systems | 1,998 | |
Using Digital Concept Maps in Conflict Resolution Studies: Implications for Students' Argumentative Skills, Domain-Specific Knowledge, and Academic Efficacy. | While argumentation emerges as one of the major learning skills in the twenty-first century, a somewhat opaque landscape is revealed in terms of identifying its potential in enhancing higher-education students' domain-specific knowledge. In this study, argumentation-for-learning activity with digital concept mapping (C... | 10.3389/fpsyg.2022.882370 | 35,874,352 | Frontiers in psychology | 2,022 | ||
Teaching video neuroimages: pulsatile proptosis. | A 44-year-old man with neurofibromatosis type 1 had been aware that his right eye pulsated. His visual acuity was 20/15 in both eyes and his intraocular pressures were normal. He had 4 mm of right exophthalmos and there was pulse-synchronous pulsation of the right eye (video on the Neurology® Web site at www.neurology.... | 10.1212/01.wnl.0000436066.35760.24 | 24,249,796 | D000328:Adult; D005094:Exophthalmos; D006801:Humans; D008297:Male; D009456:Neurofibromatosis 1; D059906:Neuroimaging; D009462:Neurology; D013100:Sphenoid Bone; D014057:Tomography, X-Ray Computed | Neurology | 2,013 | |
De novo protein synthesis is required for lytic cycle reactivation of Epstein-Barr virus, but not Kaposi's sarcoma-associated herpesvirus, in response to histone deacetylase inhibitors and protein kinase C agonists. | The oncogenic human gammaherpesviruses, Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV), are latent in cultured lymphoma cells. We asked whether reactivation from latency of either virus requires de novo protein synthesis. Using Northern blotting and quantitative reverse transcriptase PCR, w... | 10.1128/JVI.00982-07 | 17,596,302 | D001374:Azacitidine; D015152:Blotting, Northern; D002460:Cell Line; D003513:Cycloheximide; D004268:DNA-Binding Proteins; D000077209:Decitabine; D004791:Enzyme Inhibitors; D015870:Gene Expression; D004854:Herpesvirus 4, Human; D019288:Herpesvirus 8, Human; D056572:Histone Deacetylase Inhibitors; D006801:Humans; D006877:... | Journal of virology | 2,007 | C068382:BRLF1 protein, Human herpesvirus 4; C063676:BZLF1 protein, Herpesvirus 4, Human; D004268:DNA-Binding Proteins; D004791:Enzyme Inhibitors; D056572:Histone Deacetylase Inhibitors; D006877:Hydroxamic Acids; D017874:Immediate-Early Proteins; D011500:Protein Synthesis Inhibitors; D012333:RNA, Messenger; D012367:RNA,... |
Comparison of three methods of determining oxygen consumption and resting energy expenditure. | Resting energy expenditure (REE) in intensive care unit patients was evaluated by three methods--indirect calorimetry (REE-IC), Fick equation (REE-F), and estimation from the Harris-Benedict equation (REE-HB). The mean REE-IC and REE-F values did not differ significantly. However, both values were significantly higher ... | 2,921,120 | D000368:Aged; D002153:Calorimetry, Indirect; D002407:Catheterization, Swan-Ganz; D003422:Critical Care; D002149:Energy Intake; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009751:Nutritional Requirements; D010101:Oxygen Consumption; D012146:Rest | The Journal of the American Osteopathic Association | 1,989 | ||
Cross-cultural adaptation and validation of the Foot Function Index to Spanish. | BACKGROUND
The purpose of this study was to adapt and validate the Foot Function Index to the Spanish (FFI-Sp) following the guidelines of the American Academy of Orthopaedic Surgeons.
METHODS
A cross-sectional study 80 participants with some foot pathology. A statistical analysis was made, including a correlation st... | 24,480,497 | D000328:Adult; D003431:Cross-Cultural Comparison; D003430:Cross-Sectional Studies; D005260:Female; D005534:Foot Diseases; D006801:Humans; D008297:Male; D011795:Surveys and Questionnaires | Foot and ankle surgery : official journal of the European Society of Foot and Ankle Surgeons | 2,014 | ||
A 4-Week Electronic-Mentoring Employment Intervention for Youth With Physical Disabilities: Pilot Randomized Controlled Trial. | BACKGROUND
Youth with disabilities are more likely to live in poverty and be unemployed compared with youth without disabilities. Such trends are often a result of a lack of support, inaccessible jobs, environmental barriers, and discriminatory attitudes toward people with disabilities. Youth with disabilities also fac... | 10.2196/12653 | 31,518,302 | JMIR pediatrics and parenting | 2,019 | ||
Response to bleomycin of Escherichia coli mutants deficient in DNA repair. | The effect of bleomycin on the colony forming ability of Escherichia coli K12 strains in exponential growth at 37 degrees C was not affected by introducing recA13, lexA1, polA1 and uvrA6 mutations. For cells starved for amino acids, wild type strains became ten-fold more resistant to bleomycin, but again introducing le... | 10.7164/antibiotics.32.1181 | 93,597 | D001761:Bleomycin; D003470:Culture Media; D004260:DNA Repair; D004926:Escherichia coli; D005720:Gamma Rays; D005838:Genotype; D009154:Mutation | The Journal of antibiotics | 1,979 | D003470:Culture Media; D001761:Bleomycin |
Mesenchymal stem cell therapy for liver fibrosis/cirrhosis. | Liver fibrosis represents a common outcome of most chronic liver diseases. Advanced fibrosis leads to cirrhosis for which no effective treatment is available except liver transplantation. Because of the limitations of liver transplantation, alternative therapeutic strategies are an urgent need to find. Recently, mesenc... | 10.21037/atm.2020.02.119 | 32,775,363 | Annals of translational medicine | 2,020 | ||
Trends in civilian penetrating brain injury: A review of 26,871 patients. | INTRODUCTION
The aim of our study is to analyze the 5 years' trends, mortality rate, and factors that influence mortality after civilian penetrating traumatic brain injury (pTBI).
METHODS
We performed a 5-year-analysis of all trauma patients diagnosed with pTBI in the TQIP. Our outcome measures were trends of pTBI.
... | 10.1016/j.amjsurg.2018.11.034 | 30,558,803 | D000293:Adolescent; D000328:Adult; D000070642:Brain Injuries, Traumatic; D005260:Female; D020197:Head Injuries, Penetrating; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013997:Time Factors; D055815:Young Adult | American journal of surgery | 2,019 | |
Effect of labyrinthectomy on the dynamic vestibulo-ocular counterrol reflex in the rhesus monkey. | Timeline records of eyeball counterrotation to constant speed rotations about the line of sight were examined in the Rhesus monkey via a linear transformer measurement system using a contact lens. Normal monkeys exhibited a decrease in the amplitude ratio of eye-to-chair motion and an increasing phase lag between eye a... | 809,033 | D000337:Aerospace Medicine; D000818:Animals; D007758:Ear, Inner; D005133:Eye Movements; D000882:Haplorhini; D008253:Macaca mulatta; D012018:Reflex; D013307:Streptomycin; D014722:Vestibule, Labyrinth | Aviation, space, and environmental medicine | 1,975 | D013307:Streptomycin | |
Multifunctional silk-heparin biomaterials for vascular tissue engineering applications. | Over the past 30 years, silk has been proposed for numerous biomedical applications that go beyond its traditional use as a suture material. Silk sutures are well tolerated in humans, but the use of silk for vascular engineering applications still requires extensive biocompatibility testing. Some studies have indicated... | 24,099,708 | D001672:Biocompatible Materials; D001808:Blood Vessels; D006493:Heparin; D006801:Humans; D047011:Silk; D023822:Tissue Engineering | Biomaterials | 2,014 | D001672:Biocompatible Materials; D047011:Silk; D006493:Heparin | |
Barriers to control syphilis and HIV vertical transmission in the health care system in the city of Sao Paulo. | OBJECTIVE
The objective of this study was to identify possible barriers to control vertical transmission of syphilis and HIV through the analysis of the orientation process of pregnant women from prenatal care to the obstetric center at an university hospital in Sao Paulo (Reference) and their return (with their expose... | 25,388,489 | D000328:Adult; D001938:Brazil; D060085:Coinfection; D005260:Female; D015658:HIV Infections; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy; D012189:Retrospective Studies; D013587:Syphilis; D055815:Young Adult | Revista brasileira de epidemiologia = Brazilian journal of epidemiology | 2,014 | ||
Halobaculum roseum sp. nov., isolated from underground salt deposits. | Two extremely halophilic archaea, strains D90T and D93, were isolated from underground salt deposits of Yunnan salt mine, China. Both strains were pleomorphic or short rods, non-motile, Gram-negative and required 1.7 M NaCl for growth, with optimum at 3.4 M. Mg2+ was not required for growth. Multiple copies of the 16S ... | 10.1099/ijsem.0.001663 | 28,475,027 | D001482:Base Composition; D002681:China; D019641:DNA, Archaeal; D006017:Glycolipids; D006216:Halobacteriaceae; D008906:Mining; D009693:Nucleic Acid Hybridization; D010715:Phosphatidylglycerols; D010743:Phospholipids; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S; D017422:Sequence Analysis, DNA; D012965:Sodium Chloride | International journal of systematic and evolutionary microbiology | 2,017 | D019641:DNA, Archaeal; D006017:Glycolipids; C407124:PGP-Me; D010715:Phosphatidylglycerols; D010743:Phospholipids; D012336:RNA, Ribosomal, 16S; D012965:Sodium Chloride |
Nanoscale Reduced Graphene Oxide-Mediated Photothermal Therapy Together with IDO Inhibition and PD-L1 Blockade Synergistically Promote Antitumor Immunity. | Despite the potential efficacy of immune checkpoint blockade for effective treatment of cancer, this therapeutic modality is not generally curative, and only a fraction of patients respond. Combination approaches provide strategies to target multiple antitumor immune pathways to induce synergistic antitumor immunity. H... | 10.1021/acsami.8b18751 | 30,582,788 | D000818:Animals; D060890:B7-H1 Antigen; D018414:CD8-Positive T-Lymphocytes; D045744:Cell Line, Tumor; D005260:Female; D006108:Graphite; D006801:Humans; D006979:Hyperthermia, Induced; D007111:Immunity, Cellular; D050503:Indoleamine-Pyrrole 2,3,-Dioxygenase; D007371:Interferon-gamma; D007694:Killer Cells, Natural; D05137... | ACS applied materials & interfaces | 2,019 | D060890:B7-H1 Antigen; C498919:Cd274 protein, mouse; C000611649:IFNG protein, mouse; D050503:Indoleamine-Pyrrole 2,3,-Dioxygenase; C000628730:graphene oxide; D006108:Graphite; D007371:Interferon-gamma |
[Effect of the combined action of sodium nitrite and fenitrothion on certain biochemical parameters in rat blood]. | The aim of the study was explaining of the combined action of low doses of sodium nitrite and fenitrothion on certain biochemical parameters in rat blood. The experiment was carried out on male adult Wistar rats. The animals were divided into 4 experimental groups: group I receiving 10 mg/kg of sodium nitrite, group II... | 2,602,857 | D000818:Animals; D001769:Blood; D004357:Drug Synergism; D005278:Fenitrothion; D008297:Male; D009573:Nitrites; D051381:Rats; D011919:Rats, Inbred Strains; D012977:Sodium Nitrite | Roczniki Panstwowego Zakladu Higieny | 1,989 | D009573:Nitrites; D012977:Sodium Nitrite; D005278:Fenitrothion | |
The neurobeachin gene spans the common fragile site FRA13A. | Common fragile sites are normal constituents of chromosomal structure prone to chromosomal breakage. In humans, the cytogenetic locations of more than 80 common fragile sites are known. The DNA at 11 of them has been defined and characterized at the molecular level. According to the Genome Database, the common fragile ... | 10.1007/s00439-005-0083-z | 16,244,873 | D001321:Autistic Disorder; D001483:Base Sequence; D002352:Carrier Proteins; D002478:Cells, Cultured; D043283:Chromosome Fragile Sites; D002874:Chromosome Mapping; D022202:Chromosomes, Artificial, Bacterial; D002882:Chromosomes, Human, Pair 13; D004247:DNA; D017931:DNA Primers; D006801:Humans; D017404:In Situ Hybridizat... | Human genetics | 2,006 | D002352:Carrier Proteins; D017931:DNA Primers; C498595:NBEA protein, human; D009419:Nerve Tissue Proteins; D004247:DNA |
Caloric restriction and genomic stability. | Caloric restriction (CR) without malnutrition is the only experimental manipulation that has consistently been shown to increase the mean and maximum lifespan of laboratory rodents. It has been suggested that CR extends the longevity of rodents and reduces the incidence of age-related pathological lesions by reducing t... | 10,885,805 | D000375:Aging; D000818:Animals; D004249:DNA Damage; D004260:DNA Repair; D002149:Energy Intake; D005260:Female; D008136:Longevity; D008297:Male; D012106:Research; D012377:Rodentia | The journal of nutrition, health & aging | 1,999 | ||
Can linoleic acid improve the quality of frozen thawed bull sperm? | BACKGROUND
Cryopreservation is known to have a detrimental effect on the motility, viability and membrane integrity of sperm cells.
OBJECTIVE
The aim of this study was to investigate the effect of various amount of linoleic acid supplementation to the Tris extender, on bull sperm parameters, DNA integrity and oxidati... | 25,583,007 | D000818:Animals; D002417:Cattle; D015925:Cryopreservation; D003451:Cryoprotective Agents; D004249:DNA Damage; D019787:Linoleic Acid; D008297:Male; D018384:Oxidative Stress; D055101:Semen Analysis; D012662:Semen Preservation; D013081:Sperm Motility; D013094:Spermatozoa | Cryo letters | 2,014 | D003451:Cryoprotective Agents; D019787:Linoleic Acid | |
New families of hetero-tri-spin 2p-3d-4f complexes: synthesis, crystal structures, and magnetic properties. | In this work we report the synthesis, crystal structures, and magnetic behavior of 2p-3d-4f heterospin systems containing the nitroxide radical 4-azido-2,2,6,6-tetramethylpiperidine-1-oxyl radical (N3tempo). These compounds were synthesized through a one-pot reaction by using [Cu(hfac)2], [Ln(hfac)3] (hfac = hexafluoro... | 10.1021/ic5008044 | 24,964,044 | Inorganic chemistry | 2,014 | ||
Is radiofrequency ablation equal to surgical re-resection for recurrent hepatocellular carcinoma meeting the Milan criteria? A meta-analysis. | PURPOSE
To evaluate the clinical efficacy and safety of radiofrequency ablation (RFA) with surgical re-resection (SRR) in patients with postoperative recurrent hepatocellular carcinoma (RHCC) meeting the Milan criteria.
METHODS
A literature search was performed to identify comparative studies addressing outcomes of b... | 25,778,320 | D006528:Carcinoma, Hepatocellular; D017115:Catheter Ablation; D016009:Chi-Square Distribution; D018572:Disease-Free Survival; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D016017:Odds Ratio; D018579:Patient Selection; D012307:Risk Factors; D... | Journal of B.U.ON. : official journal of the Balkan Union of Oncology | 2,015 | ||
Second generation of temporary implantable nitinol device (iTind) in men with LUTS: 2 year results of the MT-02-study. | OBJECTIVES
Assessing medium-term functional results of a novel minimally-invasive treatment for lower urinary tract symptoms due to BPO with the second generation of the temporary implantable nitinol device (iTind; Medi-Tate Ltd®, Israel): 2-year follow-up of a single-arm, prospective, international multicenter study. ... | 10.1007/s00345-020-03140-z | 32,124,019 | D000328:Adult; D000497:Alloys; D005500:Follow-Up Studies; D006801:Humans; D059411:Lower Urinary Tract Symptoms; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011470:Prostatic Hyperplasia; D019736:Prostheses and Implants; D011474:Prosthesis Design; D013997:Time Factors; D016896:Treatment Outcome; D055... | World journal of urology | 2,020 | D000497:Alloys; C013616:nitinol |
Plutonium isotopes in Northern Xinjiang, China: Level, distribution, sources and their contributions. | Plutonium in the environment has drawn significant attentions due to its radiotoxicity in high concentration and source term linked with nuclear accidents and contaminations. The isotopic ratio of plutonium is source dependent and can be used as a fingerprint to discriminate the sources of radioactive contaminant. 239P... | 10.1016/j.envpol.2020.114929 | 32,540,598 | D002681:China; D007554:Isotopes; D011005:Plutonium; D011834:Radiation Monitoring; D011847:Radioactive Fallout; D012990:Soil Pollutants, Radioactive; D014875:Water Pollutants, Radioactive | Environmental pollution (Barking, Essex : 1987) | 2,020 | D007554:Isotopes; D011847:Radioactive Fallout; D012990:Soil Pollutants, Radioactive; D014875:Water Pollutants, Radioactive; D011005:Plutonium |
Covering of Plate after Anterior Cervical Fusion in Patients with Complete Spinal Cord Injury to Prevent Esophageal Injury: Technical Note. | BACKGROUND
Esophageal injury after anterior corpectomy and fusion is a rare but life-threatening complication. It may cause mediastinitis due to anatomical continuity between the retropharyngeal space and the mediastinum, with reported high mortality rates. The acute and subacute injuries are most commonly of iatrogeni... | 10.1055/s-0040-1710547 | 32,911,553 | D000328:Adult; D001860:Bone Plates; D016025:Bone Transplantation; D002574:Cervical Vertebrae; D004939:Esophageal Perforation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007431:Intraoperative Complications; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011782:Quadriplegia; D01... | Journal of neurological surgery. Part A, Central European neurosurgery | 2,020 | |
Purification and localization of intraflagellar transport particles and polypeptides. | The growth and maintenance of almost all cilia and flagella are dependent on the proper functioning of the process of intraflagellar transport (IFT). This includes the primary cilia of most cells in humans that are in interphase or the G(o) phase of the cell cycle. The model system for the study of IFT is the flagella ... | 10.1007/978-1-60761-376-3_11 | 19,768,432 | D000818:Animals; D002458:Cell Fractionation; D002696:Chlamydomonas; D002923:Cilia; D005407:Flagella; D008855:Microscopy, Electron, Scanning; D010316:Particle Size; D021381:Protein Transport; D015800:Protozoan Proteins | Methods in molecular biology (Clifton, N.J.) | 2,009 | D015800:Protozoan Proteins |
Eosinophilic bronchitis, eosinophilic granuloma, and eosinophilic bronchopneumopathy in 75 dogs (2006-2016). | BACKGROUND
Eosinophilic lung disease is a poorly understood inflammatory airway disease that results in substantial morbidity.
OBJECTIVE
To describe clinical findings in dogs with eosinophilic lung disease defined on the basis of radiographic, bronchoscopic, and bronchoalveolar lavage fluid (BAL) analysis. Categories... | 10.1111/jvim.15605 | 31,468,629 | D000818:Animals; D001987:Bronchiectasis; D029481:Bronchitis, Chronic; D001992:Bronchoalveolar Lavage Fluid; D001999:Bronchoscopy; D004283:Dog Diseases; D004285:Dogs; D004802:Eosinophilia; D004803:Eosinophilic Granuloma; D005260:Female; D008297:Male; D011657:Pulmonary Eosinophilia; D013902:Radiography, Thoracic; D012189... | Journal of veterinary internal medicine | 2,019 | |
Endocrine responses to growth hormone releasing hormone and corticotropin releasing hormone in early-onset Alzheimer's disease. | In a study of the hypothalamic-pituitary-somatotropic (HPS) and the hypothalamic-pituitary-adrenal (HPA) systems in early-onset Alzheimer's disease (AD), 10 drug-naive patients and matched controls were given 50 micrograms growth hormone releasing hormone (GHRH) at 9 a.m. and 100 micrograms corticotropin releasing horm... | 10.1016/0165-1781(90)90063-b | 2,173,839 | D000324:Adrenocorticotropic Hormone; D000368:Aged; D000544:Alzheimer Disease; D005260:Female; D013006:Growth Hormone; D013007:Growth Hormone-Releasing Hormone; D006801:Humans; D006854:Hydrocortisone; D007030:Hypothalamo-Hypophyseal System; D007334:Insulin-Like Growth Factor I; D008297:Male; D008875:Middle Aged; D010913... | Psychiatry research | 1,990 | D007334:Insulin-Like Growth Factor I; D000324:Adrenocorticotropic Hormone; D013006:Growth Hormone; D013007:Growth Hormone-Releasing Hormone; D006854:Hydrocortisone |
H+ISFET-based biosensor for determination of penicillin G. | A biosensor based on an H+ ion sensitive field effect transistor (H+(-)ISFET) and penicillin G acylase has been developed. The response time of the sensor to different concentrations of penicillin G was 30 s. In a 20 mM phosphate buffer at pH 7.0, the linear range of the calibration curve was from 0.5 to 8 mM. The coef... | 10.1016/s0956-5663(98)00003-7 | 9,839,390 | D015374:Biosensing Techniques; D002021:Buffers; D005069:Evaluation Studies as Topic; D006863:Hydrogen-Ion Concentration; D010399:Penicillin Amidase; D010400:Penicillin G; D011522:Protons; D015203:Reproducibility of Results; D014173:Transistors, Electronic | Biosensors & bioelectronics | 1,998 | D002021:Buffers; D011522:Protons; D010399:Penicillin Amidase; D010400:Penicillin G |
The mediating role of posttraumatic stress reactions in the relationship between child abuse and physical health complaints in adolescence and young adulthood. | Background: Child abuse is associated with physical health problems in adolescence and adulthood, but the mechanisms involved are unclear. A possible mediating effect of posttraumatic stress reactions (PTSR) linking child abuse with later physical health complaints has not been fully investigated. Objective: The curren... | 10.1080/20008198.2019.1608719 | 31,143,411 | European journal of psychotraumatology | 2,019 | ||
Concurrent performances: effect of punishment contingent on the switching response. | Pigeons' key-pecking responses were maintained under concurrently available variable-interval schedules of reinforcement. Responses in the presence of two different key-colors were reinforced on two independent and concurrent variable-interval schedules of food reinforcement, each associated with one of the key colors ... | 10.1901/jeab.1971.16-51 | 16,811,534 | Journal of the experimental analysis of behavior | 1,971 | ||
Utilization of hemodiafiltration as treatment modality in renal replacement therapy for end-stage renal disease patients--a global perspective. | The worldwide demand for renal replacement therapy (RRT) is constantly rising. In order to support both medical communities and healthcare authorities in their decision-making processes, it has become increasingly interesting to provide quantitative overviews on the global development of the number of end-stage renal d... | 10.1159/000333634 | 22,188,698 | D000349:Africa; D003625:Data Collection; D005060:Europe; D014943:Global Health; D017583:Hemodiafiltration; D006801:Humans; D007676:Kidney Failure, Chronic; D007843:Latin America; D009656:North America; D010530:Peritoneal Dialysis; D006435:Renal Dialysis; D017582:Renal Replacement Therapy; D012189:Retrospective Studies | Contributions to nephrology | 2,011 | |
Impact of prone surgical positioning on the scoliotic spine. | OBJECTIVE
To study the impact of patient-specific prone positioning on the sagittal and coronal curves of scoliotic spines, including the impact of various patient and surgical frame factors.
SUMMARY OF BACKGROUND DATA
Prone operative positioning has been shown to impact the geometry of various individual spinal segm... | 10.1097/BSD.0b013e318211ffa6 | 21,423,056 | D000328:Adult; D003198:Computer Simulation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008953:Models, Anatomic; D056888:Patient Positioning; D016684:Prone Position; D011857:Radiographic Image Interpretation, Computer-Assisted; D015203:Reproducibility of Results; D012600:Scoliosis; D012680:Sensi... | Journal of spinal disorders & techniques | 2,012 | |
Prospective randomized trial of paravertebral block for patients undergoing breast cancer surgery. | BACKGROUND
The goal of the current study was to evaluate the effect of regional anesthesia using paravertebral block (PVB) on postoperative pain after breast surgery.
METHODS
Patients undergoing unilateral breast surgery without reconstruction were randomized to general anesthesia (GA) only or PVB with GA and pain sc... | 10.1016/j.amjsurg.2008.11.043 | 19,427,625 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000765:Anesthesia, Conduction; D001943:Breast Neoplasms; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009407:Nerve Block; D010147:Pain Measurement; D010149:Pain, Postoperative | American journal of surgery | 2,009 | |
Remote ischaemic preconditioning versus no remote ischaemic preconditioning for vascular and endovascular surgical procedures. | BACKGROUND
Despite advances in perioperative care, elective major vascular surgical procedures carry a significant risk of morbidity and mortality. Remote ischaemic preconditioning is initiated by brief, non-lethal periods of ischaemia in a vascular bed different from the one which will be subjected to ischaemic insult... | 10.1002/14651858.CD008472.pub2 | 22,161,429 | D006801:Humans; D019194:Ischemic Preconditioning; D016032:Randomized Controlled Trials as Topic; D014656:Vascular Surgical Procedures | The Cochrane database of systematic reviews | 2,011 | |
Periphery of ethylnitrosourea-induced spinal gliomas in rats with special reference to the vascular structure. | The histology and ultrastructure of ten spinal cord gliomas, mainly oligodendrogliomas, induced transplacentally in rat with ethylnitrosourea were studied. The characteristic feature of seven spinal tumours was distinct delineation of neoplastic tissue from the edematous surrounding zone by a ring of irregular, prolife... | 10.1007/BF00695507 | 3,604,577 | D000818:Animals; D001808:Blood Vessels; D002196:Capillaries; D005038:Ethylnitrosourea; D005910:Glioma; D008854:Microscopy, Electron; D051381:Rats; D011919:Rats, Inbred Strains; D013120:Spinal Cord Neoplasms | Acta neuropathologica | 1,987 | D005038:Ethylnitrosourea |
Multiple brown tumours of the upper extremity in a patient with secondary hyperparathyroidism as a result of chronic renal failure. | A man with chronic renal failure was referred to the hand clinic because of massive osteolytic tumours in his right arm. Secondary hyperparathyroidism and brown tumours were suggested, and he was treated by subtotal parathyroidectomy. Rapid reduction of the vast tumours was noted postoperatively. | 10.3109/02844311003714674 | 22,455,576 | D000368:Aged; D001707:Biopsy, Needle; D001859:Bone Neoplasms; D017809:Fatal Outcome; D006084:Graft Rejection; D006801:Humans; D006962:Hyperparathyroidism, Secondary; D007150:Immunohistochemistry; D007676:Kidney Failure, Chronic; D016030:Kidney Transplantation; D008279:Magnetic Resonance Imaging; D008297:Male; D010010:O... | Journal of plastic surgery and hand surgery | 2,012 | |
Aldosterone reduces crypt colon permeability during low-sodium adaptation. | Fluid and electrolyte absorption by colonic crypts depends on the transport properties of crypt cellular and paracellular routes and of the pericryptal sheath. As a low-Na(+) diet increases aldosterone and angiotensin II secretion, either hormone could affect absorption. Control and adrenalectomized (ADX) Sprague-Dawle... | 10.1007/s00232-005-0772-5 | 16,440,180 | D000222:Adaptation, Physiological; D000450:Aldosterone; D000804:Angiotensin II; D000818:Animals; D003106:Colon; D004039:Diet, Sodium-Restricted; D007408:Intestinal Absorption; D008297:Male; D010539:Permeability; D051381:Rats; D017207:Rats, Sprague-Dawley; D012982:Sodium, Dietary | The Journal of membrane biology | 2,005 | D012982:Sodium, Dietary; D000804:Angiotensin II; D000450:Aldosterone |
Immobilization of naringin onto chitosan substrates by using ozone activation. | Ozone oxidation can easily produce peroxides containing active free radicals that can be used for the surface modification of biomaterials. This process is highly efficient and nontoxic. In this research, naringin, an HMG-CoA reductase inhibitor that can promote bone formation, was immobilized onto a chitosan film usin... | 24,317,428 | D000469:Alkaline Phosphatase; D000818:Animals; D002454:Cell Differentiation; D002470:Cell Survival; D002478:Cells, Cultured; D048271:Chitosan; D024042:Collagen Type I; D044950:Flavanones; D058574:Integrin-Binding Sialoprotein; D015675:Osteocalcin; D010012:Osteogenesis; D010126:Ozone; D010545:Peroxides; D010766:Phosphor... | Colloids and surfaces. B, Biointerfaces | 2,014 | D024042:Collagen Type I; D044950:Flavanones; D058574:Integrin-Binding Sialoprotein; D010545:Peroxides; D051785:Smad Proteins; D015675:Osteocalcin; D010126:Ozone; D048271:Chitosan; D000469:Alkaline Phosphatase; C005274:naringin | |
Management of the pregnant patient with idiopathic thrombocytopenic purpura. | Infants born to pregnant women with idiopathic thrombocytopenic purpura can develop thrombocytopenia, because the antiplatelet antibody that causes the illness can cross the placenta. The impact of this disease on pregnancy has been studied by analyzing case reports, but this method can give inaccurate estimates. In th... | 10.7326/0003-4819-99-6-796 | 6,359,999 | D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic; D011296:Prenatal Diagnosis; D011446:Prospective Studies; D011696:Purpura, Thrombocytopenic; D012306:Risk | Annals of internal medicine | 1,983 | |
Improving children's dental health. | Surveys show that tooth decay in young children is becoming concentrated in more deprived sectors of the population. Only by targeting families with young children in underprivileged areas will dental health be improved further. An analysis of dental health promotion advice has shown that simple, direct advice to "brus... | 12,449,062 | D002648:Child; D003152:Community Health Nursing; D006267:Health Education, Dental; D006801:Humans; D008880:Midwifery; D011204:Poverty Areas; D011320:Primary Health Care; D014076:Tooth Diseases; D014078:Tooth Eruption; D006113:United Kingdom | The journal of family health care | 2,002 | ||
The Doppler probe for planning septofasciocutaneous advancement flaps on the plantar aspect of the foot: anatomical study and clinical applications. | A 5-MHz Doppler probe was utilized to identify the perforating septofasciocutaneous vessels on the plantar aspect of the right and left feet of 10 healthy subjects. Each audible perforator was marked, and each foot was photographed, scanned into a personal computer, and standardized to 8 inches high by 4 inches wide. A... | 10.1016/s1067-2516(00)80044-7 | 11,055,019 | D000328:Adult; D002102:Cadaver; D017719:Diabetic Foot; D005260:Female; D005528:Foot; D016523:Foot Ulcer; D049669:History, 16th Century; D049672:History, 19th Century; D049673:History, 20th Century; D049690:History, Ancient; D006801:Humans; D008297:Male; D008875:Middle Aged; D010934:Planning Techniques; D012867:Skin; D0... | The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons | 2,000 | |
Attenuation of methamphetamine-induced effects through the antagonism of sigma (sigma) receptors: Evidence from in vivo and in vitro studies. | Methamphetamine (METH) and many other abused substances interact with sigma receptors. sigma receptors are found on dopaminergic neurons and can modulate dopaminergic neurotransmission. Antisense knock down of sigma receptors also mitigates METH-induced stimulant effects, suggesting that these proteins are viable medic... | 10.1016/j.euroneuro.2008.07.006 | 18,755,577 | D000818:Animals; D001522:Behavior, Animal; D001831:Body Temperature; D001921:Brain; D045744:Cell Line, Tumor; D048430:Cell Shape; D016207:Cytokines; D004298:Dopamine; D050483:Dopamine Plasma Membrane Transport Proteins; D018765:Dopamine Uptake Inhibitors; D004305:Dose-Response Relationship, Drug; D008297:Male; D008694:... | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology | 2,008 | D016207:Cytokines; D050483:Dopamine Plasma Membrane Transport Proteins; D018765:Dopamine Uptake Inhibitors; C470324:N-phenethylpiperidine oxalate; D010070:Oxalates; D010880:Piperidines; D017480:Receptors, sigma; D008694:Methamphetamine; D004298:Dopamine |
Cardiovascular risk evaluated by C-reactive protein levels in diabetic and obese Mexican subjects. | BACKGROUND
Previous studies have reported elevated levels of C-reactive protein (CRP) in obese and diabetic subjects, but it is unclear whether both these conditions have an additive effect on the variability of serum CRP levels.
METHODS AND RESULTS
The study enrolled 385 men and women who were classified into 4 grou... | 10.1253/circj.72.1170 | 18,577,830 | D000328:Adult; D000368:Aged; D015992:Body Mass Index; D002097:C-Reactive Protein; D003327:Coronary Disease; D003924:Diabetes Mellitus, Type 2; D005260:Female; D006801:Humans; D007249:Inflammation; D015850:Interleukin-6; D016014:Linear Models; D008297:Male; D008800:Mexico; D008875:Middle Aged; D009765:Obesity; D010976:P... | Circulation journal : official journal of the Japanese Circulation Society | 2,008 | D015850:Interleukin-6; D002097:C-Reactive Protein |
The efficacy of a brief alcohol intervention combined with %CDT feedback in patients being treated for type 2 diabetes and/or hypertension. | OBJECTIVE
Alcohol biomarkers are being developed to improve a physician's ability to identify and intervene with patients with chronic medical problems adversely affected by heavy alcohol use. This article reports the findings of a brief intervention trial which included feedback to patients of their carbohydrate-defic... | 10.15288/jsa.2004.65.631 | 15,536,773 | D000328:Adult; D000437:Alcoholism; D003924:Diabetes Mellitus, Type 2; D030141:Feedback, Psychological; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D014168:Transferrin | Journal of studies on alcohol | 2,004 | D014168:Transferrin; C056759:carbohydrate-deficient transferrin |
Catheter-based renal denervation for treatment of resistant hypertension. | Hypertension is a common disease associated with important cardiovascular complications. Persistent blood pressure of 140/90 or higher despite combined use of a reninangiotensin system blocker, calcium channel blocker and a diuretic at highest tolerated doses constitutes resistant hypertension. Excess sympathetic activ... | 10.1177/2048004013486634 | 24,175,081 | JRSM cardiovascular disease | 2,013 | ||
Does robot-assisted laparoscopic ileocystoplasty (RALI) reduce peritoneal adhesions compared with open surgery? | OBJECTIVES
To compare perioperative outcomes between open ileocystoplasty and robot-assisted laparoscopic ileocystoplasty (RALI) in a porcine model, as objective data comparing outcomes between these two approaches in children with neurogenic bladder are lacking. We specifically examined differences in postoperative pe... | 10.1111/bju.12284 | 24,053,691 | D000818:Animals; D005260:Female; D010535:Laparoscopy; D061646:Operative Time; D010532:Peritoneal Diseases; D012371:Robotics; D034421:Sus scrofa; D013552:Swine; D000267:Tissue Adhesions; D001743:Urinary Bladder; D014547:Urinary Diversion | BJU international | 2,014 | |
Sequence polymorphisms within the pMGA genes and pMGA antigenic variants in Mycoplasma gallisepticum. | Antigenic variants of Mycoplasma gallisepticum major surface lipoprotein, pMGA, are encoded by a large gene family. In this study sequence analyses of the PCR-amplified pMGA genes showed two types of sequences similar to the pMGA1.2 gene in M. gallisepticum strains. They differed in the sequence encoding a proline-rich... | 10.1111/j.1574-6968.2000.tb09003.x | 10,689,179 | D000595:Amino Acid Sequence; D000911:Antibodies, Monoclonal; D000940:Antigenic Variation; D001426:Bacterial Proteins; D001483:Base Sequence; D004269:DNA, Bacterial; D018604:Epitope Mapping; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D005810:Multigene Family... | FEMS microbiology letters | 2,000 | D000911:Antibodies, Monoclonal; D001426:Bacterial Proteins; D004269:DNA, Bacterial; C079720:M9 protein, Mycoplasma gallisepticum |
The immune system as anti-tumor sentinel: molecular requirements for an anti-tumor immune response. | The concept behind immune surveillance against cancer is that tumor cells continuously develop, but that there may not be clinical evidence of their presence because the immune system recognizes the cells as foreign and destroys them. A clear role for the immune system in preventing and/or eliminating tumors is emergin... | 10,468,184 | D000818:Animals; D006801:Humans; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D009369:Neoplasms; D013602:T-Lymphocytes, Cytotoxic | Critical reviews in oncogenesis | 1,999 | ||
Development of a modified electrode with amine-functionalized TiO2/multi-walled carbon nanotubes nanocomposite for electrochemical sensing of the atypical neuroleptic drug olanzapine. | In this work, using of amine-functionalized TiO2/multi-walled carbon nanotubes (NH2-TiO2-MWCNTs) nanocomposite for modification of glassy carbon electrode (GCE) was investigated. The nanocomposite was characterized by Fourier transformed infrared spectroscopy, transmission electron microscopy and scanning electron micr... | 24,094,200 | D000588:Amines; D014150:Antipsychotic Agents; D001569:Benzodiazepines; D002384:Catalysis; D055664:Electrochemical Techniques; D004566:Electrodes; D006801:Humans; D006863:Hydrogen-Ion Concentration; D053761:Nanocomposites; D037742:Nanotubes, Carbon; D000077152:Olanzapine; D010084:Oxidation-Reduction; D013499:Surface Pro... | Materials science & engineering. C, Materials for biological applications | 2,013 | D000588:Amines; D014150:Antipsychotic Agents; D037742:Nanotubes, Carbon; D013607:Tablets; D001569:Benzodiazepines; C009495:titanium dioxide; D014025:Titanium; D000077152:Olanzapine | |
The species of the genus Diamesa (Diptera, Chironomidae) known to occur in Italian Alps and Apennines. | Some rare species from Italian Alps, belonging to the genus Diamesa Meigen, 1835 (Diptera, Chironomidae) are here redescribed as adult males, because only old, incomplete descriptions are available for these taxa. Terminology of male genitalia is reviewed, diagnostic features are illustrated in detail, and notes on bio... | 10.11646/zootaxa.4193.2.7 | 27,988,720 | D063147:Animal Distribution; D000825:Animal Structures; D000818:Animals; D049628:Body Size; D002683:Chironomidae; D017753:Ecosystem; D005260:Female; D007558:Italy; D008297:Male; D009929:Organ Size | Zootaxa | 2,016 | |
[Allgrove's syndrome]. | INTRODUCTION
Triple A syndrome is an autosomal recessive disease causing achalasia, alacrima and adrenal involvement with isolated glucocorticoid deficiency. Less than 70 cases have been reported worldwide. We report a case of familial adrenal insufficiency with hyperpigmentation diagnosed in a 14 month-old child.
CA... | 11,907,967 | D000309:Adrenal Insufficiency; D002675:Child, Preschool; D015352:Dry Eye Syndromes; D004931:Esophageal Achalasia; D006801:Humans; D008297:Male; D008548:Melanosis; D010375:Pedigree; D013577:Syndrome | Annales de dermatologie et de venereologie | 2,001 | ||
Development, and effect of water temperature on development rate, of pikeperch Sander lucioperca embryos. | Knowledge of embryo development is essential to the application of reproductive biotechnology in aquaculture, including for pikeperch Sander lucioperca. We describe pikeperch embryo development and demonstrated effects of temperature on the duration of embryogenesis. Developmental stages in embryos incubated at 15 °C w... | 10.1016/j.theriogenology.2017.07.050 | 28,822,905 | D000818:Animals; D004625:Embryo, Nonmammalian; D047108:Embryonic Development; D005260:Female; D008297:Male; D010473:Perciformes; D013696:Temperature; D014867:Water | Theriogenology | 2,017 | D014867:Water |
MiR-203 over-expression promotes prostate cancer cell apoptosis and reduces ADM resistance. | OBJECTIVE
Extra-cellular signal regulated kinase (ERK)/mitogen activated protein kinase (MAPK) signaling pathway is widely involved in cell proliferation, apoptosis, and drug resistance. MAPK kinase 1 (MEK1) is the upstream protein kinase of ERK that can activate ERK/MAPK signaling pathway. microRNA 203 (MiR-203) down-... | 10.26355/eurrev_201806_15253 | 29,949,147 | D053607:Adrenomedullin; D017209:Apoptosis; D045744:Cell Line, Tumor; D019008:Drug Resistance, Neoplasm; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D020935:MAP Kinase Signaling System; D008297:Male; D035683:MicroRNAs; D011471:Prostatic Neoplasms | European review for medical and pharmacological sciences | 2,018 | C507862:ADM protein, human; C546703:MIRN203 microRNA, human; D035683:MicroRNAs; D053607:Adrenomedullin |
Risk factors for epithelial ovarian cancer in Italy. | In a case-control study conducted between May 1979 and February 1980, in Milan, Italy, to evaluate risk factors for ovarian cancer, various reproductive and menstrual characteristics, marital status, education, history of various diseases, and lifetime drug use were examined among 161 women with histologically proven e... | 10.1093/oxfordjournals.aje.a113353 | 7,081,202 | D000328:Adult; D000368:Aged; D004812:Epidemiologic Methods; D005260:Female; D006801:Humans; D007558:Italy; D008423:Maternal Age; D008598:Menstruation; D008875:Middle Aged; D010051:Ovarian Neoplasms; D010298:Parity; D012189:Retrospective Studies; D012306:Risk | American journal of epidemiology | 1,982 | |
Some effects of reduced energy intake on the development of anaplasmosis in Bos indicus cross steers. | Some effects of the plane of nutrition on the development of anaplasmosis in Brahman cross steers were investigated. Batches of 39 and 30 Brahman cross steers, aged approximately 27 months were each divided by stratified randomisation into 4 groups of similar mean PCV and body weight. Two similar experiments, designate... | 10.1111/j.1751-0813.1978.tb05522.x | 687,262 | D000712:Anaplasmosis; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001769:Blood; D001835:Body Weight; D002417:Cattle; D002418:Cattle Diseases; D006400:Hematocrit; D008297:Male | Australian veterinary journal | 1,978 | |
Artefacts produced by suture traction during incisional biopsy of oral lesions. | The aim of this study is to compare the artefacts ascribed to the technique of incisional biopsy using a punch or scalpel and the influence of suture use for traction and delivery of the specimen. A total of 160 samples were obtained from 10 fresh pig tongues by four experienced oral surgeons. Handling artefacts (squee... | 10.1046/j.1365-2273.2002.00619.x | 12,472,529 | D000818:Animals; D016477:Artifacts; D001706:Biopsy; D009055:Mouth; D013048:Specimen Handling; D013537:Sutures; D013552:Swine; D014059:Tongue; D014143:Traction | Clinical otolaryngology and allied sciences | 2,002 | |
An Articular Cartilage Repair Model in Common C57Bl/6 Mice. | To analyze the genetic and biomolecular mechanisms underlying cartilage repair, an optimized mouse model of osteochondral repair is required. Although several models of articular cartilage injury in mice have recently been established, the articular surface in adult C57Bl/6 mice heals poorly. Since C57Bl/6 mice are the... | 10.1089/ten.TEC.2014.0440 | 25,560,195 | D000375:Aging; D000818:Animals; D002358:Cartilage, Articular; D004195:Disease Models, Animal; D051379:Mice; D012038:Regeneration | Tissue engineering. Part C, Methods | 2,015 | |
Mental imagery changes multisensory perception. | Multisensory interactions are the norm in perception, and an abundance of research on the interaction and integration of the senses has demonstrated the importance of combining sensory information from different modalities on our perception of the external world. However, although research on mental imagery has reveale... | 23,810,539 | D000161:Acoustic Stimulation; D001307:Auditory Perception; D001921:Brain; D006801:Humans; D007088:Illusions; D007092:Imagination; D010775:Photic Stimulation; D013067:Speech Perception; D014796:Visual Perception; D055815:Young Adult | Current biology : CB | 2,013 | ||
Facing the urban-rural gap in patients with chronic kidney disease: Evidence from inpatients with urban or rural medical insurance in central China. | BACKGROUND
In view of the irreversible pathology of progressive exacerbation, the societal burden of chronic kidney disease (CKD) is increasing along with the rise in total health expenditure. Meanwhile, disparities remain among urban and rural citizens with different types of health insurance. This study aimed to asse... | 10.1371/journal.pone.0209259 | 30,596,680 | D000328:Adult; D000368:Aged; D002681:China; D003430:Cross-Sectional Studies; D005260:Female; D005102:Health Expenditures; D054625:Healthcare Disparities; D006760:Hospitalization; D006801:Humans; D007348:Insurance, Health; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D051436:Renal Insufficiency, Chronic; ... | PloS one | 2,018 | |
Purpose-built national burns center: The Israeli experience. | The opening of the National Burns Center (NBC) in Sheba Medical Center (SMC) in 2014 was a keystone point in the development of specialized burns trauma services for Israel to ensure burn care and disaster planning at international standards. The NBC is a purpose-built, level 1 burns trauma center that receives patient... | 10.1111/nhs.12405 | 29,356,274 | D000046:Academic Medical Centers; D002053:Burn Units; D002056:Burns; D006801:Humans; D007557:Israel; D007902:Length of Stay; D009313:National Health Programs | Nursing & health sciences | 2,018 | |
Haplotype distribution of and linkage disequilibrium between four polymorphic markers near the CFTR locus in Brazilian cystic fibrosis patients. | To contribute to a better understanding of the origin and distribution of CFTR mutations in the Brazilian population, we have investigated the linkage between four polymorphic markers (XV2c, KM19, GATT, and TUB9) within or near the CFTR locus. The distribution of alleles for each polymorphism for both parental and cyst... | 10.1353/hub.2006.0011 | 16,715,841 | D017954:Africa South of the Sahara; D000483:Alleles; D001938:Brazil; D003550:Cystic Fibrosis; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; D005828:Genetics, Population; D006239:Haplotypes; D006801:Humans; D015810:Linkage Disequilibrium; D008521:Mediterranean Islands; D010446:Peptide Fragments; D011110:P... | Human biology | 2,005 | D010446:Peptide Fragments; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; C074197:cystic fibrosis transmembrane conductance regulator (505-511) |
Serum Vitamin B12 and Methylmalonic Acid Status in Migraineurs: A Case-Control Study. | BACKGROUND
Although the exact pathophysiological mechanistic pathways that result in the initiation of migraine attacks remain unclear, there are some proposed mechanisms including neurogenic inflammation, trigeminovascular system activation, vascular dysfunction, and augmented release of nitric oxide (NO) and homocyst... | 10.1111/head.13618 | 31,471,907 | D000293:Adolescent; D000328:Adult; D000886:Anthropometry; D016022:Case-Control Studies; D017281:Cost of Illness; D018450:Disease Progression; D005260:Female; D006710:Homocysteine; D006801:Humans; D008297:Male; D008764:Methylmalonic Acid; D008875:Middle Aged; D008881:Migraine Disorders; D009752:Nutritional Status; D0101... | Headache | 2,019 | D006710:Homocysteine; D008764:Methylmalonic Acid; D014805:Vitamin B 12 |
Development of multi-directional functional near-infrared spectroscopy system for human neuroimaging studies. | Multi-directional measurement using multi-directional light sources and multi-directional photodetectors drastically increases the amount of observation data without increasing the number of optical probes. In this study, we developed a novel multi-directional functional near-infrared spectroscopy (fNIRS) system for hu... | 10.1364/BOE.10.001393 | 30,891,354 | Biomedical optics express | 2,019 | ||
Management of Fibrosing Interstitial Lung Diseases. | A proportion of patients with interstitial lung diseases (ILDs), including the ILDs that are commonly associated with autoimmune diseases, develop a progressive fibrosing phenotype characterised by worsening of lung function, dyspnoea and quality of life, and early mortality. No drugs are approved for the treatment of ... | 10.1007/s12325-019-00992-9 | 31,119,691 | D001327:Autoimmune Diseases; D018450:Disease Progression; D006801:Humans; D007166:Immunosuppressive Agents; D017563:Lung Diseases, Interstitial; D011658:Pulmonary Fibrosis; D012129:Respiratory Function Tests | Advances in therapy | 2,019 | D007166:Immunosuppressive Agents |
Learning Hybrid Image Templates (HIT) by Information Projection. | This paper presents a novel framework for learning a generative image representation-the hybrid image template (HIT) from a small number (i.e., 3 \sim 20) of image examples. Each learned template is composed of, typically, 50 \sim 500 image patches whose geometric attributes (location, scale, orientation) may adapt in ... | 10.1109/TPAMI.2011.227 | 22,144,518 | IEEE transactions on pattern analysis and machine intelligence | 2,012 | ||
Factors Associated With Attendance at a 1-yr Post-Cardiac Rehabilitation Risk Factor Check. | PURPOSE
Patients with coronary artery disease (CAD) often fail to maintain secondary prevention gains after completing cardiac rehabilitation (CR). Follow-up appointments aimed at assessing cardiac status and encouraging maintenance of health behaviors after CR completion are generally offered but not well-attended. Th... | 10.1097/HCR.0000000000000486 | 31,972,633 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000072038:Cardiac Rehabilitation; D003324:Coronary Artery Disease; D003430:Cross-Sectional Studies; D005260:Female; D015438:Health Behavior; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Complian... | Journal of cardiopulmonary rehabilitation and prevention | 2,020 | |
Three-year clinical observation of the outcomes of transepithelial and epithelial-off accelerated corneal collagen crosslinking treatment for different types of progressive keratoconus. | In the present study, the clinical and long-term effects of accelerated transepithelial corneal collagen crosslinking (ATE-CXL) and accelerated epithelial-off corneal collagen crosslinking (A-CXL) for the treatment of different types of progressive keratoconus were compared. A total of 70 patients, including 96 eyes wi... | 10.3892/etm.2020.8741 | 32,742,324 | Experimental and therapeutic medicine | 2,020 | ||
Pain, fatigue, and school functioning in children with cerebral palsy: a path-analytic model. | OBJECTIVE
This study tests a model of how pain and fatigue, independently or in combination, relate to school functioning in pediatric cerebral palsy (CP).
METHODS
One hundred eighty-nine parents of children with CP completed the Pediatric Quality of Life Inventory (PedsQL) 4.0 Generic Core Scales and the PedsQL 3.0 ... | 10.1093/jpepsy/jsl017 | 16,818,483 | D000124:Achievement; D000293:Adolescent; D002547:Cerebral Palsy; D002648:Child; D005221:Fatigue; D005260:Female; D006801:Humans; D008297:Male; D010146:Pain; D015995:Prevalence; D011788:Quality of Life; D011795:Surveys and Questionnaires | Journal of pediatric psychology | 2,007 | |
SS31 Alleviates Pressure Overload-Induced Heart Failure Caused by Sirt3-Mediated Mitochondrial Fusion. | Heart failure caused by pressure overload is one of the leading causes of heart failure worldwide, but its pathological origin remains poorly understood. It remains critical to discover and find new improvements and treatments for pressure overload-induced heart failure. According to previous studies, mitochondrial dys... | 10.3389/fcvm.2022.858594 | 35,592,397 | Frontiers in cardiovascular medicine | 2,022 | ||
Intellectual performance after presymptomatic cranial radiotherapy for leukaemia: effects of age and sex. | Cognitive outcome, as measured by verbal and performance IQs, was compared in 35 girls and 47 boys who were in first remission for acute lymphoblastic leukaemia. All children had received presymptomatic cranial radiotherapy and intrathecal methotrexate. The mean age at diagnosis was 4.2 years and the mean elapsed time ... | 10.1136/adc.73.2.136 | 7,574,857 | D000293:Adolescent; D000367:Age Factors; D001921:Brain; D002648:Child; D002675:Child, Preschool; D016371:Cranial Irradiation; D002658:Developmental Disabilities; D005260:Female; D006801:Humans; D007360:Intelligence; D017254:Leukemic Infiltration; D008297:Male; D015999:Multivariate Analysis; D054198:Precursor Cell Lymph... | Archives of disease in childhood | 1,995 | |
Associations between plasma total homocysteine, blood pressure stages and pulse wave velocity in Chinese rural community population. | The aim of the study was to examine the associations among plasma total homocysteine (tHcy) and blood pressure (BP) stages and brachial-ankle pulse wave velocity (ba-PWV) in a Chinese rural community population. In this cross-sectional study, 2148 rural community subjects with normotension and mild hypertension (HTN) w... | 10.3109/08037051.2014.997089 | 26,043,364 | D000368:Aged; D055109:Ankle Brachial Index; D001794:Blood Pressure; D002681:China; D005260:Female; D006710:Homocysteine; D006801:Humans; D006973:Hypertension; D008297:Male; D008875:Middle Aged; D063177:Pulse Wave Analysis; D012424:Rural Population | Blood pressure | 2,015 | D006710:Homocysteine |
[Investigation about prevention behavior for dust workers in machinery, ceramic, and metallurgy industry]. | OBJECTIVE
The purposes of this thesis were to study the behavior about workers exposed to dust and provide scientific basis for health promotion.
METHODS
We designed a questionnaire and carry it on the 746 dust workers in the 3 representative corporations of Machinery, Ceramic, and Metallurgy Industry. All data were ... | 21,619,801 | D000293:Adolescent; D000328:Adult; D002516:Ceramics; D002755:Choice Behavior; D004391:Dust; D005260:Female; D006801:Humans; D007221:Industry; D008297:Male; D008669:Metallurgy; D008875:Middle Aged; D016273:Occupational Exposure; D012134:Respiratory Protective Devices; D055815:Young Adult | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases | 2,011 | D004391:Dust | |
Increasing proportion of ST elevation myocardial infarction patients with coronary atherosclerosis poorly explained by standard modifiable risk factors. | Aims Identification and management of the Standard Modifiable Cardiovascular Risk Factors (SMuRFs; hypercholesterolaemia, hypertension, diabetes and smoking) has substantially improved cardiovascular disease outcomes. However, cardiovascular disease remains the leading cause of death worldwide. Suspecting an evolving p... | 10.1177/2047487317720287 | 28,703,626 | D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D003324:Coronary Artery Disease; D003920:Diabetes Mellitus; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia; D006973:Hypertension; D016014:Linear Models; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariat... | European journal of preventive cardiology | 2,017 | |
A new haemosporidian parasite from the Red-legged Seriema Cariama cristata (Cariamiformes, Cariamidae). | Haemoproteids (Haemosporida, Haemoproteidae) are a diverse group of avian blood parasites that are transmitted by hematophagous dipterans. In this study, we describe Haemoproteus pulcher sp. nov. from a Red-legged Seriema (Cariama cristata) in southeast Brazil. Analysis of the mitochondrial cytb gene indicates this par... | 10.1016/j.ijppaw.2022.02.009 | 35,399,588 | International journal for parasitology. Parasites and wildlife | 2,022 | ||
Multifunctional Biotemplated Micromotors for In Situ Decontamination of Antibiotics and Heavy Metals in Soil and Groundwater. | The ubiquitous pollution by antibiotics and heavy metal ions has posed great threats to human health and the ecological environment. Therefore, we developed a self-propelled tubular micromotor based on natural fibers as an active heterogeneous catalyst for antibiotic degradation and adsorbent for heavy metal ions in so... | 10.3390/nano13192710 | 37,836,351 | Nanomaterials (Basel, Switzerland) | 2,023 | ||
The El Niño Southern Oscillation and the historic malaria epidemics on the Indian subcontinent and Sri Lanka: an early warning system for future epidemics? | The recurrent great malaria epidemics which occurred in the Punjab province of former British India and Ceylon before the introduction of residual insecticides have been related to excessive and failing monsoon rains respectively. In the arid Punjab, rainfall facilitated breeding and increased the lifespan of the mosqu... | 10.1046/j.1365-3156.1996.d01-7.x | 8,673,827 | D004196:Disease Outbreaks; D005544:Forecasting; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D007194:India; D008288:Malaria; D009032:Mosquito Control; D011891:Rain; D012621:Seasons; D013188:Sri Lanka; D014887:Weather | Tropical medicine & international health : TM & IH | 1,996 | |
No mucosal atrophy and reduced inflammatory cells: active-controlled trial with yearlong fluticasone furoate nasal spray. | BACKGROUND
Fluticasone furoate nasal spray (FFNS) and mometasone furoate nasal spray (MFNS) are well tolerated and more effective than placebo at relieving the symptoms of seasonal and perennial allergic rhinitis. Effects of FFNS on the nasal histology have not been previously reported. This study examines the effects... | 10.2500/ajra.2012.26.3675 | 22,391,079 | D000293:Adolescent; D000328:Adult; D000369:Aged, 80 and over; D000730:Androstadienes; D001284:Atrophy; D001491:Basophils; D002465:Cell Movement; D004804:Eosinophils; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D000068656:Mometasone Furoate; D009297:Nasal Mucosa; D059085... | American journal of rhinology & allergy | 2,012 | D000730:Androstadienes; D059085:Nasal Sprays; D011244:Pregnadienediols; D000068656:Mometasone Furoate; C523187:fluticasone furoate |
Purulent meningitis in children: outcome using a standard management regimen with chloramphenicol. | We report a prospective study of 108 children aged from 2 weeks to 10 years with purulent meningitis admitted to the children's wards of Port Moresby General Hospital, 105 of whom were treated with a standard management regimen using chloramphenicol (given intramuscularly initially) as the only antibiotic. The case fat... | 10.1080/02724936.1992.11747602 | 1,283,666 | D001419:Bacteria; D002648:Child; D002675:Child, Preschool; D002701:Chloramphenicol; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D016920:Meningitis, Bacterial; D010634:Phenobarbital; D011446:Prospective Studies; D012640:Seizures; D016896:Treatment Outcome | Annals of tropical paediatrics | 1,992 | D002701:Chloramphenicol; D010634:Phenobarbital |
Inertial-load method determines maximal cycling power in a single exercise bout. | A cycle ergometer was modified to measure power (P) with resistance provided solely by the moment of inertia (I) of the flywheel. P was calculated as the product of I, angular velocity (omega), and angular acceleration (alpha). Flywheel omega and alpha were determined by means of an optical sensor and a micro-controlle... | 10.1097/00005768-199711000-00018 | 9,372,489 | D000328:Adult; D001696:Biomechanical Phenomena; D006804:Ergonomics; D015444:Exercise; D005080:Exercise Test; D006801:Humans; D008297:Male; D010807:Physical Endurance; D055585:Physical Phenomena; D010825:Physics; D015203:Reproducibility of Results | Medicine and science in sports and exercise | 1,997 | |
The effects of clofazimine, niclosamide & amphotericin B, on electron transport of Leishmania donovani promastigotes. | BACKGROUND & OBJECTIVES
The study was undertaken to explore the locus of interaction of clofazimine and niclosamide which showed substantial growth inhibition property in Leishmania donovani promastigotes.
METHODS
The uptake of final electron acceptor oxygen and 2,6-dichlorophenolindophenol (DCPIP) reduction in the e... | 11,006,656 | D000666:Amphotericin B; D000818:Animals; D000981:Antiprotozoal Agents; D002991:Clofazimine; D004579:Electron Transport; D007893:Leishmania donovani; D009534:Niclosamide | The Indian journal of medical research | 2,000 | D000981:Antiprotozoal Agents; D000666:Amphotericin B; D009534:Niclosamide; D002991:Clofazimine | |
Secreted protein acidic, rich in cysteine (SPARC), mediates cellular survival of gliomas through AKT activation. | Secreted protein acidic, rich in cysteine (SPARC), is an extracellular matrix protein expressed in many advanced cancers, including malignant gliomas. We and others have previously shown that human glioma cell lines engineered to overexpress SPARC adopt an invasive phenotype. We now show that SPARC expression increases... | 10.1074/jbc.M409630200 | 15,469,933 | D000818:Animals; D017209:Apoptosis; D053148:Caspase 3; D053179:Caspase 7; D020169:Caspases; D002417:Cattle; D045744:Cell Line, Tumor; D002470:Cell Survival; D016895:Culture Media, Serum-Free; D004789:Enzyme Activation; D005910:Glioma; D006801:Humans; D015676:Osteonectin; D019869:Phosphatidylinositol 3-Kinases; D010766:... | The Journal of biological chemistry | 2,004 | D016895:Culture Media, Serum-Free; D015676:Osteonectin; D011518:Proto-Oncogene Proteins; D011994:Recombinant Proteins; C494918:AKT1 protein, human; D017346:Protein Serine-Threonine Kinases; D051057:Proto-Oncogene Proteins c-akt; C505407:CASP3 protein, human; C505520:CASP7 protein, human; D053148:Caspase 3; D053179:Casp... |
Integrative genome and transcriptome analyses reveal two distinct types of ring chromosome in soft tissue sarcomas. | Gene amplification is a common phenomenon in malignant neoplasms of all types. One mechanism behind increased gene copy number is the formation of ring chromosomes. Such structures are mitotically unstable and during tumor progression they accumulate material from many different parts of the genome. Hence, their conten... | 10.1093/hmg/ddt479 | 24,070,870 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D051358:Cyclin-Dependent Kinase 4; D005260:Female; D005784:Gene Amplification; D020869:Gene Expression Profiling; D056726:Genetic Association Studies; D015894:Genome, Human; D025743:HMGA2 Protein; D006801:Humans; D008297:Male; D008875:Middle Aged; D020641:Polymorp... | Human molecular genetics | 2,014 | D025743:HMGA2 Protein; D016160:Retinoblastoma Protein; C497206:MDM2 protein, human; D051736:Proto-Oncogene Proteins c-mdm2; C495900:CDK4 protein, human; D051358:Cyclin-Dependent Kinase 4 |
Nocturnal enuresis: epidemiology, evaluation, and currently available treatment options. | Treatment of childhood enuresis must begin with a careful history, physical examination, urinalysis, and urine culture to determine if one is dealing with uncomplicated or complicated enuresis. The majority of patients will have uncomplicated enuresis; there are several treatment options available to the physician that... | 10.1016/s0022-3476(89)80883-2 | 2,647,951 | D000293:Adolescent; D000367:Age Factors; D001521:Behavior Therapy; D002648:Child; D002675:Child, Preschool; D003376:Counseling; D004775:Enuresis; D005260:Female; D006801:Humans; D007099:Imipramine; D008297:Male; D001743:Urinary Bladder | The Journal of pediatrics | 1,989 | D007099:Imipramine |
Molecular Mechanisms of Lead Binding to Ferrihydrite-Bacteria Composites: ITC, XAFS, and μ-XRF Investigations. | Binding of Pb(II) to ferrihydrite-Bacillus subtilis composites formed in the presence of bacterial cells were investigated through macroscopic and microscopic techniques. Diffuse layer model (DLM) fitting and isothermal titration calorimetry (ITC) analysis indicated that the hydroxyl group played a key role in Pb(II) s... | 10.1021/acs.est.9b06288 | 32,176,845 | D000327:Adsorption; D001419:Bacteria; D002151:Calorimetry; D005290:Ferric Compounds | Environmental science & technology | 2,020 | D005290:Ferric Compounds; C092844:ferric oxyhydroxide |
The Genetics of Postoperative Recurrence in Crohn Disease: A Systematic Review, Meta-analysis, and Framework for Future Work. | Background
Recurrence following abdominal surgery in Crohn disease is over 50%. The impact of genetics on postoperative recurrence is not well defined.
Methods
A literature search was conducted where inclusion required an assessment, by genotype, of postoperative recurrence. The primary endpoint was odds of surgical ... | 10.1093/crocol/otaa094 | 36,778,938 | Crohn's & colitis 360 | 2,021 | ||
Sex differences in acute coronary syndrome symptom presentation in young patients. | IMPORTANCE
Little is known about whether sex differences in acute coronary syndrome (ACS) presentation exist in young patients and what factors determine absence of chest pain in ACS presentation.
OBJECTIVES
To evaluate sex differences in ACS presentation and to estimate associations between sex, sociodemographic, ge... | 10.1001/jamainternmed.2013.10149 | 24,043,208 | D054058:Acute Coronary Syndrome; D000367:Age Factors; D002170:Canada; D002637:Chest Pain; D015897:Comorbidity; D005260:Female; D005783:Gender Identity; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012727:Sex Characteristics; D012959:Socioeconomic Factors | JAMA internal medicine | 2,013 | |
Coumarin Triazabutadienes for Fluorescent Labeling of Proteins. | The use of small-molecule fluorophores to label proteins with minimal perturbation in response to an external stimulus is a powerful tool to probe chemical and biochemical environments. Herein, we describe the use of a coumarin-modified triazabutadiene that can deliver aryl diazonium ions to fluorescently label protein... | 10.1002/cbic.201800599 | 30,341,988 | D003374:Coumarins; D005453:Fluorescence; D005456:Fluorescent Dyes; D015335:Molecular Probes; D011506:Proteins; D014226:Triazenes | Chembiochem : a European journal of chemical biology | 2,018 | D003374:Coumarins; D005456:Fluorescent Dyes; D015335:Molecular Probes; D011506:Proteins; D014226:Triazenes |
Preclinical models of breast cancer: Two-way shuttles for immune checkpoint inhibitors from and to patient bedside. | The Food and Drug Administration has lately approved atezolizumab, anti-programmed death ligand 1 (PD-L1), to be used together with nanoparticle albumin-bound (nab) paclitaxel in treating patients with triple negative breast cancer (BC) expressing PD-L1. Nonetheless, immune checkpoint inhibitors (ICIs) are still challe... | 10.1016/j.ejca.2019.08.013 | 31,606,656 | D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D060908:CTLA-4 Antigen; D002289:Carcinoma, Non-Small-Cell Lung; D059447:Cell Cycle Checkpoints; D004353:Drug Evaluation, Preclinical; D006801:Humans; D007155:Immunologic Factors; D007167:Immunotherapy; D061026:Programmed Cell Death 1 Receptor; D0... | European journal of cancer (Oxford, England : 1990) | 2,019 | D061067:Antibodies, Monoclonal, Humanized; D000970:Antineoplastic Agents; D060908:CTLA-4 Antigen; D007155:Immunologic Factors; D061026:Programmed Cell Death 1 Receptor; C000594389:atezolizumab |
Renal Medullary Carcinoma on Dual-Time Point FDG PET/CT Imaging. | Renal medullary carcinoma is a rare and highly aggressive tumor seen almost exclusively in young individuals of African descent with sickle cell disease. Here, we describe a case of a 29-year-old man, who did not have sickle cell disease, with pathologically confirmed renal medullary carcinoma using dual-time FDG PET/C... | 10.1097/RLU.0000000000003033 | 32,332,313 | D000328:Adult; D018276:Carcinoma, Medullary; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007680:Kidney Neoplasms; D008297:Male; D000072078:Positron Emission Tomography Computed Tomography; D013997:Time Factors | Clinical nuclear medicine | 2,020 | D019788:Fluorodeoxyglucose F18 |
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