title large_stringlengths 0 979 | abstract large_stringlengths 1 94.7k | doi large_stringlengths 0 71 | pmid int64 21 38.1M | mesh_terms large_stringlengths 0 1.47k | journal large_stringlengths 1 239 | pubdate int16 1.97k 2.02k | chemical_list large_stringlengths 0 1.47k |
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Regulation of thrombospondin-1 expression through AU-rich elements in the 3'UTR of the mRNA. | Thrombospondin-1 (TSP-1) is a matricellular protein that participates in numerous normal and pathological tissue processes and is rapidly modulated by different stimuli. The presence of 8 highly-conserved AU rich elements (AREs) within the 3'-untranslated region (3'UTR) of the TSP-1 mRNA suggests that post-transcriptio... | 10.2478/s11658-010-0037-x | 21,161,418 | D020413:3' Untranslated Regions; D001483:Base Sequence; D005786:Gene Expression Regulation; D057809:HEK293 Cells; D006207:Half-Life; D000081035:Heterogeneous Nuclear Ribonucleoprotein D0; D034502:Heterogeneous-Nuclear Ribonucleoprotein D; D006801:Humans; D016297:Mutagenesis, Site-Directed; D020871:RNA Stability; D01233... | Cellular & molecular biology letters | 2,011 | D020413:3' Untranslated Regions; C000630986:HNRNPD protein, human; D000081035:Heterogeneous Nuclear Ribonucleoprotein D0; D034502:Heterogeneous-Nuclear Ribonucleoprotein D; D012333:RNA, Messenger; D019700:Thrombospondin 1 |
[Distribution Characteristics and Influencing Factors of Phytoplankton Community in Harbin Urban River Network During Wet Season]. | In this study, 23 typical sampling points were selected from the Harbin urban river network during the wet season from June to August in 2019, including the Harbin section of the Songhua, Hejiagou, Majiagou, and Ashi rivers to study the distribution of phytoplankton communities. Characteristics and driving factors infl... | 10.13227/j.hjkx.202011158 | 34,212,651 | D002681:China; D000458:Cyanobacteria; D017377:Diatoms; D004784:Environmental Monitoring; D010839:Phytoplankton; D045483:Rivers; D012621:Seasons | Huan jing ke xue= Huanjing kexue | 2,021 | |
Genomic Characterisation of Vinegar Hill Virus, An Australian Nairovirus Isolated in 1983 from Argas Robertsi Ticks Collected from Cattle Egrets. | This report describes the near complete genomic sequence and subsequent analysis of Vinegar Hill virus (VINHV; tentative member of the genus Orthonairovirus, family Nairoviridae, order Bunyavirales). VINHV is the second nairovirus reported to be isolated on mainland Australia and the first to be sequenced and analysed.... | 10.3390/v9120373 | 29,206,186 | D000818:Animals; D001315:Australia; D016679:Genome, Viral; D016855:Nairovirus; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D017385:Sequence Homology; D013987:Ticks | Viruses | 2,017 | |
Is secondary hyperparathyroidism an important etiologic factor in the anemia of chronic renal failure? | Twenty patients with chronic renal failure being treated with hemodialysis were investigated in an attempt to ascertain whether hyperparathyroidism is an important etiologic factor in these patients' anemia. The patients were divided into two groups, one with hemoglobin of greater than 8 g/dl and the other with hemoglo... | 7,068,355 | D000328:Adult; D000741:Anemia, Aplastic; D001855:Bone Marrow Diseases; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary; D007676:Kidney Failure, Chronic; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis | Israel journal of medical sciences | 1,982 | ||
Salvage brachytherapy for localized prostate cancer after radiotherapy failure. | OBJECTIVES
To evaluate the effectiveness and morbidity of salvage brachytherapy for locally recurrent or persistent prostate cancer after radiotherapy failure.
METHODS
In this retrospective study, 49 patients of median age 73.3 years (range 52.9 to 86.9) with biopsy-proven localized prostate cancer underwent interact... | 10.1016/s0090-4295(98)00492-0 | 9,886,580 | D000206:Actuarial Analysis; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy; D018572:Disease-Free Survival; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms; D012189:Retrospective Studies; D016879:Salvage Therapy; D015996:Survival Rate; D017211:Treatment Failure | Urology | 1,999 | |
Influenza vaccination uptake and its determinants during the 2019-2020 and early 2020-2021 flu seasons among migrants in Shanghai, China: a cross-sectional survey. | Influenza vaccination coverage has generally been low in mainland China. However, few studies have attempted to measure influenza vaccination coverage among internal migrants in China who are at an increased risk of influenza infections. This study assessed influenza vaccination coverage and the factors associated with... | 10.1080/21645515.2021.2016006 | 35,021,017 | D000086382:COVID-19; D002681:China; D003430:Cross-Sectional Studies; D006801:Humans; D007252:Influenza Vaccines; D007251:Influenza, Human; D058873:Pandemics; D012621:Seasons; D014171:Transients and Migrants; D014611:Vaccination | Human vaccines & immunotherapeutics | 2,022 | D007252:Influenza Vaccines |
Carbon fiber composites inspection and defect characterization using active infrared thermography: numerical simulations and experimental results. | Composite materials are widely used in the aeronautic industry. One of the reasons is because they have strength and stiffness comparable to metals, with the added advantage of significant weight reduction. Infrared thermography (IT) is a safe nondestructive testing technique that has a fast inspection rate. In active ... | 10.1364/AO.55.000D46 | 27,958,438 | Applied optics | 2,016 | ||
Expression of rat complement control protein Crry on tumor cells inhibits rat natural killer cell-mediated cytotoxicity. | Crry is a rodent membrane-bound inhibitor of complement activation and is a structural and functional analog of the human complement inhibitors decay-accelerating factor and membrane cofactor protein. We found previously that expression of rat Crry on a human tumor cell line enhances tumorigenicity in nude rats. In thi... | 10.1182/blood.V100.9.3304 | 12,384,431 | D000230:Adenocarcinoma; D000818:Animals; D000920:Antibody-Dependent Cell Cytotoxicity; D000954:Antigens, Surface; D001943:Breast Neoplasms; D018957:CD59 Antigens; D003176:Complement C3; D003165:Complement System Proteins; D003602:Cytotoxicity, Immunologic; D006239:Haplotypes; D006801:Humans; D007140:Immunoglobulin Fab ... | Blood | 2,002 | D000954:Antigens, Surface; D018957:CD59 Antigens; D003176:Complement C3; C081470:Cr1l protein, mouse; C513105:Cr1l protein, rat; D007140:Immunoglobulin Fab Fragments; D009895:Opsonin Proteins; D011956:Receptors, Cell Surface; D011951:Receptors, Complement; D017463:Receptors, Complement 3b; D011993:Recombinant Fusion Pr... |
Leukotriene D(4) enhances the function of endothelin-1-primed fibroblasts. | Airway inflammation is accompanied by structural changes, termed remodeling, that lead to lung dysfunction over the long term. Although both endothelin-1 (ET-1) and cysteinyl leukotrienes (CysLTs) appear to be involved in airway remodeling in several lung diseases, how these molecules interact remains largely unknown. ... | 10.1016/j.clim.2007.05.018 | 17,627,891 | D000085:Acetates; D000199:Actins; D003521:Cyclopropanes; D019332:Endothelin-1; D004797:Enzyme-Linked Immunosorbent Assay; D005333:Fetus; D005347:Fibroblasts; D005434:Flow Cytometry; D006801:Humans; D020024:Leukotriene Antagonists; D017998:Leukotriene D4; D008168:Lung; D020782:Matrix Metalloproteinases; D008565:Membrane... | Clinical immunology (Orlando, Fla.) | 2,007 | D000085:Acetates; D000199:Actins; D003521:Cyclopropanes; D019332:Endothelin-1; D020024:Leukotriene Antagonists; D008565:Membrane Proteins; D010446:Peptide Fragments; D011347:Procollagen; D011804:Quinolines; D012333:RNA, Messenger; D018077:Receptors, Leukotriene; D013440:Sulfides; D019714:Tissue Inhibitor of Metalloprot... |
Role of human and mouse HspB1 in metastasis. | Heat shock proteins (HSP) are a group of physiologically-essential, highly-conserved proteins that are induced by heat shock, as well as by other environmental and pathophysiological stressors. The twentyseven kDa heat shock protein (Hsp27; HspB1) is highly expressed in tumor tissues of patients diagnosed with cancer a... | 10.2174/156652412803306701 | 22,804,237 | D000375:Aging; D000818:Animals; D000970:Antineoplastic Agents; D017209:Apoptosis; D002470:Cell Survival; D055551:HSP27 Heat-Shock Proteins; D006360:Heat-Shock Proteins; D006801:Humans; D051379:Mice; D018832:Molecular Chaperones; D009362:Neoplasm Metastasis; D009363:Neoplasm Proteins; D017510:Protein Folding; D017382:Re... | Current molecular medicine | 2,012 | D000970:Antineoplastic Agents; D055551:HSP27 Heat-Shock Proteins; C057725:HSPB1 protein, human; D006360:Heat-Shock Proteins; C486113:Hsbp1 protein, mouse; D018832:Molecular Chaperones; D009363:Neoplasm Proteins; D017382:Reactive Oxygen Species |
Legionella pneumophila in Patients with Pneumonia at a Referral Hospital, New Delhi, India, 2015-2020. | Legionnaires' disease (LD) is an established cause of pneumonia, and the disease remains largely underdiagnosed. Even though LD has been reported from many parts of the world, only sporadic cases have been reported in India. During February 2015-January 2020, we enrolled 597 patients with radiographically confirmed pne... | 33,319,733 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D007194:India; D016952:Legionella pneumophila; D007877:Legionnaires' Disease; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012307:Risk Factors; D01689... | The American journal of tropical medicine and hygiene | 2,020 | ||
Participatory Surveillance of COVID-19 in Lesotho via Weekly Calls: Protocol for Cell Phone Data Collection. | BACKGROUND
The increase in cell phone ownership in low- and middle-income countries (LMIC) has created an opportunity for low-cost, rapid data collection by calling participants on their cell phones. Cell phones can be mobilized for a myriad of data collection purposes, including surveillance. In LMIC, cell phone-based... | 10.2196/31236 | 34,351,866 | JMIR research protocols | 2,021 | ||
The effectiveness of nonfinancial interventions and monetary incentives on COVID-19 vaccination: A meta-analysis. | OBJECTIVE
Although mass vaccination is critical for curbing the spread of COVID-19 and saving lives, vaccine rates remain suboptimal in most countries, calling for effective behavioral interventions to promote vaccinations. Nonfinancial behavioral interventions and monetary incentives are commonly used to promote COVID... | 10.1037/hea0001288 | 37,126,030 | D006801:Humans; D000086663:COVID-19 Vaccines; D009042:Motivation; D000086382:COVID-19; D014611:Vaccination; D058873:Pandemics | Health psychology : official journal of the Division of Health Psychology, American Psychological Association | 2,023 | D000086663:COVID-19 Vaccines |
Experimental study of the survival of metastatic cancer cells in corneal organ culture. | PURPOSE
Transmission of donor malignancy to the recipient could be one of the most disastrous complications of corneal grafting. Because of the scarcity of donor tissue and the lack of sufficient scientific evidence, the harvest of donor tissues from deaths due to systemic malignancy is permitted. This study was conduc... | 10.1167/iovs.05-1007 | 16,565,366 | D000230:Adenocarcinoma; D001943:Breast Neoplasms; D002294:Carcinoma, Squamous Cell; D002448:Cell Adhesion; D049109:Cell Proliferation; D002470:Cell Survival; D018920:Coculture Techniques; D003110:Colonic Neoplasms; D003315:Cornea; D005456:Fluorescent Dyes; D006650:Histocompatibility Testing; D006801:Humans; D008175:Lun... | Investigative ophthalmology & visual science | 2,006 | D005456:Fluorescent Dyes; D009930:Organic Chemicals; C451241:PKH67 |
Acridine orange as a coreactant for efficient electrogenerated chemiluminescence of tris(2,2'-bipyridine)ruthenium(ii) and its use in selective and sensitive detection of thiourea. | A new and efficient anodic Ru(bpy)32+ ECL system by using acridine orange (3,6-Bis(dimethylamino)acridine, AO) as a coreactant was reported in a neutral medium. The developed Ru(bpy)32+-AO system displayed a higher ECL intensity than that of the classic Ru(bpy)32+- oxalate ECL system, and was further exploited for the ... | 10.1039/d0cc01273d | 32,255,109 | D000165:Acridine Orange; D049449:Luminescence; D008163:Luminescent Measurements; D015394:Molecular Structure; D009942:Organometallic Compounds; D013890:Thiourea | Chemical communications (Cambridge, England) | 2,020 | D009942:Organometallic Compounds; C415768:tris(2,2'-bipyridyl)ruthenium(II); D000165:Acridine Orange; D013890:Thiourea |
[Development and validation of a perceived stress questionnaire recommended as a follow-up indicator in occupational medicine]. | This work was originated from the concern for the availability of a short, acceptable and reliable instrument for self-assessment of perceived stress. The questionnaire was designed to be routinely applied within a visit at an Occupational Medical Center. A new questionnaire was developed with this aim, consisting of 9... | 9,333,549 | D000328:Adult; D003674:Defense Mechanisms; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases; D010555:Personality Inventory; D011594:Psychometrics; D015203:Reproducibility of Results; D013315:Stress, Psychological; D016526:Workload | L'Encephale | 1,997 | ||
Bioaccumulation of methylmercury versus inorganic mercury in rice (Oryza sativa L.) grain. | Mercury (Hg) bioaccumulation in aquatic food webs has been much studied, motivated from high Hg levels found in many fish species important for human consumption. Hg bioaccumulation in terrestrial food chains have received little attention and assumed to be of minor importance. However, recent studies showed that rice ... | 10.1021/es903565t | 20,476,782 | D000383:Agriculture; D002681:China; D008628:Mercury; D008767:Methylmercury Compounds; D008906:Mining; D012275:Oryza; D018570:Risk Assessment; D012639:Seeds; D012987:Soil | Environmental science & technology | 2,010 | D008767:Methylmercury Compounds; D012987:Soil; D008628:Mercury |
Inhibitors of the oncogenic transcription factor AP-1 from Podocarpus latifolius. | An activator protein-1 (AP-1) based bioassay-guided phytochemical investigation on Podocarpus latifolius led to the isolation of three new sempervirol-type diterpenes, cycloinumakiol (1), inumakal (2), and inumakoic acid (3), along with three known norditerpenes (4-6). Compounds 4 and 6 were responsible for the observe... | 10.1021/np100736y | 21,306,129 | D004224:Diterpenes; D006801:Humans; D015394:Molecular Structure; D028201:Pinaceae; D024301:Plant Bark; D018517:Plant Roots; D013636:Tanzania; D018808:Transcription Factor AP-1 | Journal of natural products | 2,011 | C558232:11,10-oxymethylenecyclopent-14-isopropyl-8,11,13-podocarpatriene; C558233:11-hydroxy-14-isopropyl-8,11,13-podocarpatrien-19-al; C558234:11-hydroxy-14-isopropyl-8,11,13-podocarpatrien-19-oic acid; D004224:Diterpenes; D018808:Transcription Factor AP-1 |
Heterologous overexpression of the GbTCP5 gene increased root hair length, root hair and stem trichome density, and lignin content in transgenic Arabidopsis. | Teosinte branched1/cycloidea/proliferating cell factor1 (TCP) is a plant-specific protein family member involved in plant growth and development. However, the functions of most members of the cotton TCP family are unknown. In this study, the GbTCP5 gene encodes a sea-island cotton class II TCP CIN subclass transcriptio... | 10.1016/j.gene.2020.144954 | 32,683,079 | D017360:Arabidopsis; D032561:Cotton Fiber; D004268:DNA-Binding Proteins; D003368:Gossypium; D008031:Lignin; D018517:Plant Roots; D030821:Plants, Genetically Modified; D011401:Promoter Regions, Genetic; D014157:Transcription Factors; D015533:Transcriptional Activation; D064201:Trichomes | Gene | 2,020 | D004268:DNA-Binding Proteins; D014157:Transcription Factors; D008031:Lignin |
Ileus rate after abdominal wall reconstruction: a retrospective analysis of two clinical trials. | PURPOSE
Postoperative ileus (POI) is the paralytic disruption of gastrointestinal motility, a common complication following abdominal wall reconstruction that often leads to increased patient morbidity and length of stay (LOS). We reviewed two randomized clinical trials to determine POI rates, predictive factors, LOS, ... | 10.1007/s10029-022-02687-7 | 36,319,900 | D006801:Humans; D034861:Abdominal Wall; D059685:Herniorrhaphy; D045823:Ileus; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors; D002986:Clinical Trials as Topic | Hernia : the journal of hernias and abdominal wall surgery | 2,022 | |
Reverse transcription-polymerase chain reaction detection of collagen transcripts in healing human wounds. | The aim of this study was to analyse the expression of COl1A1, COl1A2 and COl3A1 in 6 mm diameter punch biopsies obtained from human wounds. Total RNA was isolated from biopsies taken from Sacrococcygeal pilonidal sinus excision cavities at weekly intervals between surgery and clinical closure. cDNAs were generated fro... | 10.1111/j.1365-2362.1995.tb01742.x | 7,556,374 | D001706:Biopsy; D003094:Collagen; D018076:DNA, Complementary; D006801:Humans; D010864:Pilonidal Sinus; D016133:Polymerase Chain Reaction; D011347:Procollagen; D014158:Transcription, Genetic; D014945:Wound Healing | European journal of clinical investigation | 1,995 | D018076:DNA, Complementary; D011347:Procollagen; D003094:Collagen |
Local morphologic changes related to laryngeal carcinoma. | In a series of 178 patients who underwent partial or total laryngectomy for laryngeal carcinoma, the morphologic changes at a distance from the neoplasm were investigated with whole organ serial sections. We found 60 cases with extensive squamous metaplasia of the epithelium outside of the vocal cords, 24 case with hyp... | 10.1177/030089168507100103 | 3,984,044 | D002278:Carcinoma in Situ; D002294:Carcinoma, Squamous Cell; D004848:Epithelium; D006801:Humans; D006965:Hyperplasia; D007820:Laryngeal Mucosa; D007822:Laryngeal Neoplasms; D007830:Larynx; D008679:Metaplasia; D012470:Salivary Glands, Minor; D014827:Vocal Cords | Tumori | 1,985 | |
Radical excision of invasive thymoma with intracardiac extension. | A patient with a low grade malignant thymoma who also had pleural, pericardial and cardiac invasion with intracardiac extension, presented with signs of superior vena cava obstruction, moderate hepatosplenomegaly and a mediastinal mass on a plain chest radiograph. Radical excision requiring cardiopulmonary bypass for t... | 7,929,553 | D000328:Adult; D002315:Cardiopulmonary Bypass; D006338:Heart Neoplasms; D006529:Hepatomegaly; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms; D009361:Neoplasm Invasiveness; D010997:Pleural Neoplasms; D013163:Splenomegaly; D013479:Superior Vena Cava Syndrome; D013945:Thymoma; D013953:Thymus Neoplasms | The Journal of cardiovascular surgery | 1,994 | ||
Emotional Openness, problematic eating behaviours, and overweight in adolescents. | Overweight, a common health condition in adolescence, has been linked with difficulties in emotional processing. This study investigates associations between emotional processing, conceptualised through the model of Emotional Openness (EO), problematic eating behaviours, including Eating in the Absence of Hunger and di... | 25,682,365 | D000293:Adolescent; D015992:Body Mass Index; D004435:Eating; D004644:Emotions; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D006815:Hunger; D007266:Inhibition, Psychological; D008297:Male; D008960:Models, Psychological; D009765:Obesity; D050177:Overweight; D057566:Self Report | Eating behaviors | 2,015 | ||
A simple microassay for the estimation of renin concentration in plasma. | A simple assay for the measurement of renin concentration and renin substrate concentration in microliter quantities of rat plasma is described. In the plasma renin concentration assay 5 microliter of rat plasma was incubated for 2 hr at 37 degrees C in the presence of 20 microliter renin substrate (plasma from nephrec... | 10.1016/0160-5402(80)90031-5 | 6,256,589 | D000803:Angiotensin I; D000806:Angiotensin-Converting Enzyme Inhibitors; D000808:Angiotensinogen; D000818:Animals; D008297:Male; D008832:Microchemistry; D011863:Radioimmunoassay; D051381:Rats; D012083:Renin; D012965:Sodium Chloride; D013552:Swine | Journal of pharmacological methods | 1,980 | D000806:Angiotensin-Converting Enzyme Inhibitors; D000808:Angiotensinogen; D012965:Sodium Chloride; D000803:Angiotensin I; D012083:Renin |
Evaluation of sampling strategies to characterize dissolved oxygen conditions in northern Gulf of Mexico estuaries. | Dissolved oxygen was continuously monitored in eight sites of northern Gulf of Mexico estuaries in August, 1990. Monte Carlo analyses on subsamples of the data were used to evaluate several commonly used monitoring strategies. Monitoring strategies which involve single point sampling of dissolved oxygen may often miscl... | 10.1007/BF00545979 | 24,227,380 | Environmental monitoring and assessment | 1,993 | ||
Development of the Electronic Social Network Assessment Program Using the Center for eHealth and Wellbeing Research Roadmap. | BACKGROUND
The number of Web-based psychological and behavioral interventions is growing. Beyond their theoretical underpinnings, a key factor to the success of these interventions is how they are designed and developed to ensure usability over a new method of delivery. Our team has adapted ecomapping, a tool for visua... | 10.2196/humanfactors.7845 | 28,855,149 | JMIR human factors | 2,017 | ||
Differential recovery of membrane proteins after extraction by aqueous methanol and trifluoroethanol. | Cell membrane proteome analysis is limited by inherent membrane hydrophobicity. Conventional membrane protein extraction techniques use detergents, chaotropes and organic acids that require sample clean-up or pH adjustment, and are associated with significant sample loss. We extracted membrane proteins from red blood c... | 10.1002/pmic.200600579 | 17,436,264 | D000328:Adult; D002462:Cell Membrane; D002853:Chromatography, Liquid; D015180:Electrophoresis, Gel, Two-Dimensional; D004912:Erythrocytes; D006801:Humans; D013058:Mass Spectrometry; D008565:Membrane Proteins; D000432:Methanol; D008969:Molecular Sequence Data; D012997:Solvents; D014270:Trifluoroethanol | Proteomics | 2,007 | D008565:Membrane Proteins; D012997:Solvents; D014270:Trifluoroethanol; D000432:Methanol |
A DnaK homolog in Myxococcus xanthus is involved in social motility and fruiting body formation. | Myxococcus xanthus is a gram-negative soil bacterium which exhibits a complex life cycle and social behavior. In this study, two developmental mutants of M. xanthus were isolated through Tn5 transposon mutagenesis. The mutants were found to be defective in cellular aggregation as well as in sporulation. Further phenoty... | 10.1128/JB.180.2.218-224.1998 | 9,440,508 | D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D018840:HSP70 Heat-Shock Proteins; D009154:Mutation; D016941:Myxococcus xanthus; D010641:Phenotype; D013696:Temperature | Journal of bacteriology | 1,998 | D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D018840:HSP70 Heat-Shock Proteins; C063842:dnaK protein, E coli |
Incidence of anxiety in the Lundby Study: changes over time during a quarter of a century. | 2,550 persons from a geographically delimited area in Sweden were examined and described by a team of 4 psychiatrists in 1947. Mental disorders, personality traits, social factors etc. were recorded for all but 1% of the population. Irrespective of domicile the same persons were examined in the same way first 10, then ... | 10.1159/000118387 | 3,444,521 | D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001007:Anxiety; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013548:Sweden | Neuropsychobiology | 1,987 | |
Intravascular ultrasound guided wiring re-entry technique for complex chronic total occlusions. | BACKGROUND
The successful recanalization rate of chronic total occlusion (CTO) lesions without retrograde collaterals available is always low. Intravascular ultrasound (IVUS) may be useful to guide the subintimal guidewire to re-enter the true lumen. We evaluated the clinical feasibility and efficacy of the IVUS-guided... | 10.1111/joic.12518 | 29,726,047 | D000368:Aged; D062906:Cardiac Catheters; D002908:Chronic Disease; D054059:Coronary Occlusion; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010043:Outcome and Process Assessment, Health Care; D062645:Percutaneous Coronary Intervention; D025321:Surgery, Computer-Assisted; D013624:Taiwan; D016896:Tr... | Journal of interventional cardiology | 2,018 | |
IL-5 secretion by allergen-stimulated CD4+ T cells in primary culture: relationship to expression of allergic disease. | BACKGROUND
IL-5-producing allergen-specific T cells are thought to play a prominent role in the pathogenesis of allergic inflammation. We hypothesized that T cell allergen-driven IL-5 synthesis is elevated in patients with atopic disease as compared with that in atopic patients free of disease and nonatopic control sub... | 10.1016/s0091-6749(97)70085-x | 9,111,503 | D000485:Allergens; D000818:Animals; D039741:Antigens, Dermatophagoides; D001249:Asthma; D015496:CD4-Positive T-Lymphocytes; D002478:Cells, Cultured; D004306:Dose-Response Relationship, Immunologic; D006023:Glycoproteins; D006801:Humans; D007371:Interferon-gamma; D015848:Interleukin-5; D008925:Mites; D012220:Rhinitis; D... | The Journal of allergy and clinical immunology | 1,997 | D000485:Allergens; D039741:Antigens, Dermatophagoides; D006023:Glycoproteins; D015848:Interleukin-5; D014373:Tuberculin; D007371:Interferon-gamma |
A new experimental model for the investigation of sequential hermaphroditism. | The stunning sexual transformation commonly triggered by age, size or social context in some fishes is one of the best examples of phenotypic plasticity thus far described. To date our understanding of this process is dominated by studies on a handful of subtropical and tropical teleosts, often in wild settings. Here w... | 10.1038/s41598-021-02063-y | 34,819,550 | D000818:Animals; D054304:Anti-Mullerian Hormone; D047072:Aromatase Inhibitors; D004958:Estradiol; D005260:Female; D029941:Fish Proteins; D005399:Fishes; D005786:Gene Expression Regulation; D006066:Gonads; D057850:Hermaphroditic Organisms; D008297:Male; D023421:Models, Animal; D010641:Phenotype; D012727:Sex Characterist... | Scientific reports | 2,021 | D047072:Aromatase Inhibitors; D029941:Fish Proteins; D013739:Testosterone; D004958:Estradiol; D054304:Anti-Mullerian Hormone; C003600:11-ketotestosterone |
Degradation of Antibiotics in Wastewater: New Advances in Cavitational Treatments. | Over the past few decades, antibiotics have been considered emerging pollutants due to their persistence in aquatic ecosystems. Even at low concentrations, these pollutants contribute to the phenomenon of antibiotic resistance, while their degradation is still a longstanding challenge for wastewater treatment. In the p... | 10.3390/molecules26030617 | 33,504,036 | D000900:Anti-Bacterial Agents; D006801:Humans; D062065:Wastewater; D014874:Water Pollutants, Chemical; D018508:Water Purification | Molecules (Basel, Switzerland) | 2,021 | D000900:Anti-Bacterial Agents; D062065:Waste Water; D014874:Water Pollutants, Chemical |
Steroidal Saponins from Furcraea hexapetala Leaves and Their Phytotoxic Activity. | Four new steroidal saponins (1-4) along with 13 known saponins were isolated from the leaves of Furcraea hexapetala. The new compounds were identified as (20R,22R,25R)-3β-hydroxy-5α-spirostan-12-one 3-O-{α-l-rhamnopyranosyl-(1→4)-O-β-d-glucopyranosyl-(1→3)-O-[β-d-glucopyranosyl-(1→3)-O-β-d-glucopyranosyl-(1→2)]-O-β-d-g... | 10.1021/acs.jnatprod.6b00702 | 27,797,203 | D000470:Alkaloids; D000070357:Asparagaceae; D003462:Cuba; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010840:Phytosterols; D018515:Plant Leaves; D012503:Saponins; D013237:Stereoisomerism; D013329:Structure-Activity Relationship | Journal of natural products | 2,016 | D000470:Alkaloids; D010840:Phytosterols; D012503:Saponins |
Evolution of precancerous lesions in a rural Chinese population at high risk of gastric cancer. | The pathogenesis of gastric cancer (GC), particularly of the intestinal type, is thought to involve a multistep and multifactorial process. Our objective was to determine the rates of transition from early to advanced gastric lesions in a population in Linqu County, China, where the GC rates are among the highest in th... | 10.1002/(sici)1097-0215(19991126)83:5<615::aid-ijc8>3.0.co;2-l | 10,521,796 | D000328:Adult; D000367:Age Factors; D002681:China; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011230:Precancerous Conditions; D012424:Rural Population; D012737:Sex Factors; D013274:Stomach Neopl... | International journal of cancer | 1,999 | |
Exact gram filtering and efficient backprojection for iterative CT reconstruction. | PURPOSE
Forward and backprojections are the basis of all model-based iterative reconstruction (MBIR) methods. However, computing these accurately is time-consuming. In this paper, we present a method for MBIR in parallel X-ray beam geometry that utilizes a Gram filter to efficiently implement forward and backprojection... | 10.1002/mp.15547 | 35,174,904 | D000465:Algorithms; D007091:Image Processing, Computer-Assisted; D019047:Phantoms, Imaging; D014057:Tomography, X-Ray Computed | Medical physics | 2,022 | |
Paramagnetic hexacyanometalates. The diversity of spin distribution studied by 13C and 15N MAS NMR spectroscopy. | With the aim of probing the spin density distribution in the open-shell cyanometallates Cs2K[M(CN)6] (M = Cr, Mn, Fe), K3[M(CN)6] (M = Mn, Fe), K4[M(CN)6] (M = Cr, Mn), and K4[V(CN)7] have been studied by solid-state (13)C and (15)N NMR spectroscopy. The signals appear in strongly shifted and broad ranges ((13)C, -2100... | 10.1021/ic401830f | 24,147,815 | Inorganic chemistry | 2,013 | ||
Determination of residual nonsteroidal anti-inflammatory drugs in aqueous sample using magnetic nanoparticles modified with cetyltrimethylammonium bromide by high performance liquid chromatography. | A simple and sensitive solid-phase extraction method for separation and preconcentration of trace amount of four nonsteroidal anti-inflammatory drugs (naproxen, indomethacin, diclofenac, and ibuprofen) using Fe3O4 magnetic nanoparticles modified with cetyltrimethylammonium bromide has been developed. For this purpose, ... | 10.1155/2014/127835 | 24,982,923 | D000894:Anti-Inflammatory Agents, Non-Steroidal; D000077286:Cetrimonium; D002593:Cetrimonium Compounds; D002851:Chromatography, High Pressure Liquid; D058185:Magnetite Nanoparticles; D014874:Water Pollutants, Chemical | TheScientificWorldJournal | 2,014 | D000894:Anti-Inflammatory Agents, Non-Steroidal; D002593:Cetrimonium Compounds; D058185:Magnetite Nanoparticles; D014874:Water Pollutants, Chemical; D000077286:Cetrimonium |
Comprehensive Direct Georeferencing of Aerial Images for Unmanned Aerial Systems Applications. | Optical image sensors are the most common remote sensing data acquisition devices present in Unmanned Aerial Systems (UAS). In this context, assigning a location in a geographic frame of reference to the acquired image is a necessary task in the majority of the applications. This process is denominated direct georefere... | 10.3390/s22020604 | 35,062,577 | D003625:Data Collection; D062305:Geographic Mapping | Sensors (Basel, Switzerland) | 2,022 | |
Comparison of the non-structural protein, NS1, of tick-borne and insect-borne orbiviruses. | The nucleotide sequence of RNA segment 6 of Broadhaven virus (BRDV), a tick-borne orbivirus, was determined principally from two overlapping cDNA clones and RNA end sequence analysis. The genome segment is 1714 base pairs in length and has a coding capacity for a protein of 537 amino acids, having a net charge of +4.0 ... | 10.1016/0168-1702(95)00004-a | 7,653,106 | D000595:Amino Acid Sequence; D000818:Animals; D002478:Cells, Cultured; D015967:Gene Expression Regulation, Viral; D005814:Genes, Viral; D007313:Insecta; D008969:Molecular Sequence Data; D018163:Orbivirus; D012367:RNA, Viral; D013987:Ticks; D017361:Viral Nonstructural Proteins | Virus research | 1,995 | C089209:NS1 protein, African horse sickness virus; D012367:RNA, Viral; D017361:Viral Nonstructural Proteins |
The 103Rh NMR spectroscopy and relaxometry of the rhodium formate paddlewheel complex. | The nuclear magnetic resonance (NMR) spectroscopy of spin-1/2 nuclei with low gyromagnetic ratio is challenging due to the low NMR signal strength. Methodology for the rapid acquisition of 103Rh NMR parameters is demonstrated for the case of the rhodium formate "paddlewheel" complex Rh2(HCO2)4. A scheme is described fo... | 10.1063/5.0165830 | 37,698,193 | The Journal of chemical physics | 2,023 | ||
[Current review of the epidemiology of leptospirosis]. | Spirochete bacteria Leptospira spp. is the causative agent of leptospirosis, antropozoonotic endemic disease in many parts of the world, mainly in underdeveloped countries with high levels of poverty. Its incidence and prevalence rates are higher and important in human populations living in tropical and subtropical cli... | 27,428,344 | D006801:Humans; D007922:Leptospirosis; D008800:Mexico; D015995:Prevalence | Revista medica del Instituto Mexicano del Seguro Social | 2,016 | ||
Aluminum chelation: chemistry, clinical, and experimental studies and the search for alternatives to desferrioxamine. | This review focuses on aluminum (Al) chelation, its chemistry and biology. The toxicology and biology of Al in mammalian organisms are briefly reviewed to introduce the problems associated with excessive Al exposure and accumulation and the challenges facing an effective Al chelator. The basics of Al chelation chemistr... | 10.1080/15287399409531834 | 8,301,696 | D000328:Adult; D000535:Aluminum; D000818:Animals; D002264:Carboxylic Acids; D002614:Chelating Agents; D015913:Chelation Therapy; D002648:Child; D003676:Deferoxamine; D005459:Fluorides; D006801:Humans; D007676:Kidney Failure, Chronic; D009422:Nervous System Diseases; D011817:Rabbits; D051381:Rats; D017582:Renal Replacem... | Journal of toxicology and environmental health | 1,994 | D002264:Carboxylic Acids; D002614:Chelating Agents; D000535:Aluminum; D003676:Deferoxamine; D005459:Fluorides |
Continuous recruitment, co-expression of tumour necrosis factor-alpha and matrix metalloproteinases, and apoptosis of macrophages in gout tophi. | Gout tophi are characterised by foreign body granulomas consisting of mono- and multinucleated macrophages surrounding deposits of monosodium urate microcrystals. After primary formation, granulomas grow associated with degradation of the extracellular matrix. Based on this background, we have sought (1) to investigate... | 10.1007/s004280000282 | 11,147,175 | D017209:Apoptosis; D006073:Gout; D006801:Humans; D008264:Macrophages; D020782:Matrix Metalloproteinases; D012016:Reference Values; D012867:Skin; D014409:Tumor Necrosis Factor-alpha | Virchows Archiv : an international journal of pathology | 2,000 | D014409:Tumor Necrosis Factor-alpha; D020782:Matrix Metalloproteinases |
Oncogenic Ras-mediated cell growth arrest and apoptosis are associated with increased ubiquitin-dependent cyclin D1 degradation. | The cellular responses to activated Ras vary depending on cell type. Normal cells are often induced into pathways that lead to cell growth arrest, senescence, and/or apoptosis in response to activated Ras expression. These are important protective anti-tumorigenic responses that restrict the propagation of cells bearin... | 10.1074/jbc.M002235200 | 10,781,597 | D000818:Animals; D017209:Apoptosis; D017871:Calcium-Calmodulin-Dependent Protein Kinases; D002455:Cell Division; D002460:Cell Line; D019938:Cyclin D1; D015536:Down-Regulation; D016193:G1 Phase; D038362:Glycogen Synthase Kinase 3; D006868:Hydrolysis; D020928:Mitogen-Activated Protein Kinases; D015689:Oncogene Protein p2... | The Journal of biological chemistry | 2,000 | D014452:Ubiquitins; D019938:Cyclin D1; D017871:Calcium-Calmodulin-Dependent Protein Kinases; D020928:Mitogen-Activated Protein Kinases; D038362:Glycogen Synthase Kinase 3; D015689:Oncogene Protein p21(ras) |
Comparison of meconium and neonatal hair analysis for detection of gestational exposure to drugs of abuse. | BACKGROUND
Meconium and hair are two biological markers of in utero exposure to illicit drugs.
OBJECTIVE
To compare the sensitivity of the two tests for different drugs.
SETTING
Motherisk laboratory which tests in utero drug exposure in Toronto.
METHODS
Cocaine, benzoylecgonine, opiates, cannabis, benzodiazepines... | 10.1136/fn.88.2.f98 | 12,598,495 | D002188:Cannabis; D003042:Cocaine; D006197:Hair; D006801:Humans; D013287:Illicit Drugs; D007231:Infant, Newborn; D016014:Linear Models; D008470:Meconium; D009294:Narcotics; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity | Archives of disease in childhood. Fetal and neonatal edition | 2,003 | D013287:Illicit Drugs; D009294:Narcotics; D003042:Cocaine |
Online electrochemical monitoring of nitric oxide during photodynamic therapy. | Photodynamic therapy (PDT), as a novel treatment modality, is based on the use of a photosensitizing agent with an excitation light source for the treatment of various malignancies. Its effect is mediated through reactive oxygen species and nitric oxide (NO), which are shown to be present in apoptosis. Individual diffe... | 10.1016/s1089-8603(02)00121-0 | 12,446,180 | D000622:Aminolevulinic Acid; D000818:Animals; D015374:Biosensing Techniques; D002138:Calibration; D002531:Cerebellum; D004563:Electrochemistry; D008839:Microelectrodes; D009569:Nitric Oxide; D010778:Photochemotherapy; D017319:Photosensitizing Agents; D051381:Rats; D017207:Rats, Sprague-Dawley | Nitric oxide : biology and chemistry | 2,002 | D017319:Photosensitizing Agents; D009569:Nitric Oxide; D000622:Aminolevulinic Acid |
The pharmacokinetics and pharmacodynamics of medifoxamine after oral administration in healthy elderly volunteers. | The pharmacokinetics and psychomotor effects of medifoxamine, a 5 HT reuptake inhibitory antidepressant, were studied in healthy elderly volunteers after single and multiple dosing. The elimination half life (t1/2z) after single doses of 300 mg was 2.8 h--almost identical to that found in young volunteers. After seven ... | 10.1007/BF00199882 | 8,039,537 | D000284:Administration, Oral; D000368:Aged; D000928:Antidepressive Agents; D005021:Ethylamines; D005260:Female; D006207:Half-Life; D006801:Humans; D008297:Male; D011597:Psychomotor Performance; D012016:Reference Values | European journal of clinical pharmacology | 1,994 | D000928:Antidepressive Agents; D005021:Ethylamines; C034065:medifoxamine |
[Induction of growth-associated protein-43 expression in airway afferent nerves of guinea pigs by allergic airway inflammation]. | OBJECTIVE
To investigate the mechanisms underlying sensitization of airway sensory nerves induced by allergic airway inflammation.
METHODS
Thirty-nine guinea pigs were divided randomly into three groups including group A (saline sensitized/challenged guinea pigs, n = 9), group B [ovalbumin (OVA) sensitized/saline cha... | 16,759,494 | D000485:Allergens; D000818:Animals; D019922:GAP-43 Protein; D006168:Guinea Pigs; D007249:Inflammation; D008297:Male; D009473:Neuronal Plasticity; D009475:Neurons, Afferent; D012130:Respiratory Hypersensitivity; D012137:Respiratory System | Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases | 2,006 | D000485:Allergens; D019922:GAP-43 Protein | |
Virulence genotypes and phylogenetic background of fluoroquinolone-resistant and susceptible Escherichia coli urine isolates from dogs with urinary tract infection. | The origins and virulence potential of fluoroquinolone-resistant (FQ-R) Escherichia coli from dogs with urinary tract infection (UTI) are undefined. Therefore, fluoroquinolone-resistant (n=38) or susceptible (n=62) E. coli urine isolates from dogs with UTI were characterized for phylogenetic group (A, B1, B2, D) and 61... | 10.1016/j.vetmic.2008.10.006 | 19,019,576 | D000818:Animals; D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D004283:Dog Diseases; D004285:Dogs; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli; D004927:Escherichia coli Infections; D024841:Fluoroquinolones; D005838:Genotype; D008826:Microbial Sensitivity Tests; D010802:Phylogeny; D016133:Polym... | Veterinary microbiology | 2,009 | D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D024841:Fluoroquinolones |
A Markovian event-based framework for stochastic spiking neural networks. | In spiking neural networks, the information is conveyed by the spike times, that depend on the intrinsic dynamics of each neuron, the input they receive and on the connections between neurons. In this article we study the Markovian nature of the sequence of spike times in stochastic neural networks, and in particular t... | 10.1007/s10827-011-0327-y | 21,499,739 | D000200:Action Potentials; D000818:Animals; D006801:Humans; D016014:Linear Models; D008390:Markov Chains; D009415:Nerve Net; D009433:Neural Inhibition; D016571:Neural Networks, Computer; D009474:Neurons; D013269:Stochastic Processes; D009435:Synaptic Transmission | Journal of computational neuroscience | 2,011 | |
Seven-year institutional experience in the surgical treatment of orbito-zygomatic fractures. | INTRODUCTION
Facial trauma is a common injury in the urban setting. Many studies have been published on the epidemiology of facial fractures, but few of them conducted in Brazil. The purpose of this study was to analyze the epidemiological characteristics of patients treated for orbito-zygomatic fractures at our instit... | 10.1016/j.jcms.2010.11.018 | 21,195,624 | D000063:Accidents, Traffic; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001336:Automobiles; D001860:Bone Plates; D001863:Bone Screws; D001938:Brazil; D002648:Child; D002675:Child, Preschool; D016021:Epidemiologic Studies; D005260:Female; D005593:Fracture Fixation, I... | Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery | 2,011 | |
Comparison of the in vitro efficacies of moxifloxacin and amoxicillin against Listeria monocytogenes. | Listeria monocytogenes is a facultative intracellular bacterium that causes severe infections associated with a high mortality rate. Moxifloxacin presents extended activity against gram-positive bacteria and has recently been suggested to be a potential alternative in the treatment of listeriosis. We evaluated the in v... | 10.1128/AAC.01211-07 | 18,299,415 | D000658:Amoxicillin; D000818:Animals; D001372:Aza Compounds; D002478:Cells, Cultured; D024841:Fluoroquinolones; D008089:Listeria monocytogenes; D008264:Macrophages; D051379:Mice; D008807:Mice, Inbred BALB C; D008826:Microbial Sensitivity Tests; D000077266:Moxifloxacin; D011804:Quinolines | Antimicrobial agents and chemotherapy | 2,008 | D001372:Aza Compounds; D024841:Fluoroquinolones; D011804:Quinolines; D000658:Amoxicillin; D000077266:Moxifloxacin |
Decision support methodologies for human health assessment of toxic substances: Agency for Toxic Substances and Disease Registry's perspectives on collaboration and infrastructure development among government, academia, and industry. | ATSDR's mission is to prevent or mitigate adverse human effects and diminished quality of life that result from exposure to hazardous substances from hazardous waste sites, unplanned releases, and other sources of pollution present in the environment. As part of this charge, human health assessments are performed throu... | 10.1016/0378-4274(95)03378-x | 7,570,665 | D000818:Animals; D006077:Government Agencies; D015386:Hazardous Substances; D006801:Humans; D007221:Industry; D018570:Risk Assessment | Toxicology letters | 1,995 | D015386:Hazardous Substances |
Fertility, developmental toxicity and teratogenicity in albino rats treated with methanol sub-fraction of Carica papaya seeds. | OBJECTIVE
To evaluate the status of fertility, developmental stages during gestation and teratological changes, if any, following oral administration of methanol sub-fraction (MSF) of the benzene chromatographic fraction of the chloroform extract of the seeds of Carica papaya in rats.
MATERIALS AND METHODS
The MSF wa... | 10.4103/0253-7613.83113 | 21,844,997 | Indian journal of pharmacology | 2,011 | ||
Evaluation of varying ductile fracture criteria for 42CrMo steel by compressions at different temperatures and strain rates. | Fracturing by ductile damage occurs quite naturally in metal forming processes, and ductile fracture of strain-softening alloy, here 42CrMo steel, cannot be evaluated through simple procedures such as tension testing. Under these circumstances, it is very significant and economical to find a way to evaluate the ductile... | 10.1155/2014/579328 | 24,592,175 | D002858:Chromium Alloys; D019245:Compressive Strength; D006244:Hardness; D006358:Hot Temperature; D013232:Steel | TheScientificWorldJournal | 2,014 | D002858:Chromium Alloys; D013232:Steel |
A comparison of the Xpert(®) MTB/RIF and GenoType(®) MTBDRplus assays in Georgia. | Few studies have directly compared the performance of rapid molecular diagnostic tests for tuberculosis (TB). We found that the commercially available molecular diagnostic tests Xpert(®) MTB/RIF and GenoType(®) MTBDRplus both provided timely and accurate results compared to conventional phenotypic tests in detecting TB... | 10.5588/ijtld.14.0867 | 25,946,358 | D000995:Antitubercular Agents; D004269:DNA, Bacterial; D024901:Drug Resistance, Multiple, Bacterial; D005838:Genotype; D005846:Georgia (Republic); D006801:Humans; D008826:Microbial Sensitivity Tests; D025202:Molecular Diagnostic Techniques; D009169:Mycobacterium tuberculosis; D010641:Phenotype; D011237:Predictive Value... | The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease | 2,015 | D000995:Antitubercular Agents; D004269:DNA, Bacterial |
Anthocyanin profile, antioxidant activity and enzyme inhibiting properties of blueberry and cranberry juices: a comparative study. | Cranberry (Vaccinium macrocarpon) and blueberry (Vaccinium myrtillus) juices are commonly consumed as a source of antioxidants. The aim of this study was to compare bioactivities as well as the differences in the polyphenol content and anthocyanin profile of both juices. Polyphenol and anthocyanin contents were quantif... | 10.1039/c7fo01205e | 29,038,797 | D000110:Acetylcholinesterase; D000872:Anthocyanins; D000975:Antioxidants; D029798:Blueberry Plants; D004791:Enzyme Inhibitors; D000067030:Fruit and Vegetable Juices; D006367:HeLa Cells; D006801:Humans; D008995:Monoamine Oxidase; D014442:Monophenol Monooxygenase; D029799:Vaccinium macrocarpon | Food & function | 2,017 | D000872:Anthocyanins; D000975:Antioxidants; D004791:Enzyme Inhibitors; D014442:Monophenol Monooxygenase; D008995:Monoamine Oxidase; D000110:Acetylcholinesterase |
Biomimetic microfluidic platform for the quantification of transient endothelial monolayer permeability and therapeutic transport under mimicked cancerous conditions. | Therapeutic delivery from microvasculature to cancerous sites is influenced by many factors including endothelial permeability, vascular flow rates/pressures, cancer secretion of cytokines and permeabilizing agents, and characteristics of the chosen therapeutics. This work uses bi-layer microfluidics capable of studyin... | 10.1063/1.5000377 | 29,333,203 | Biomicrofluidics | 2,018 | ||
Aspects of care for the hepatitis C positive patient. | BACKGROUND
With almost 200,000 infected Australians, hepatitis C is Australia's commonest life threatening chronic infection.
OBJECTIVE
Over 90% of the 11,000 new infections in Australia each year are associated with injecting drug use. Australia does not have a national plan for achieving control of hepatitis C. Tre... | 9,769,525 | D000998:Antiviral Agents; D019698:Hepatitis C, Chronic; D006801:Humans; D008103:Liver Cirrhosis; D016896:Treatment Outcome | Australian family physician | 1,998 | D000998:Antiviral Agents | |
Expression of Egr-1 in the brain of sleep deprived rats. | In previous research, rats subjected to prolonged sleep deprivation have shown disturbances of thermoregulation, hormonal and metabolic changes in apparent response to the thermoregulatory problems, lesions on the tail and paws, and eventual death. To search for alterations of functional activity in brain, the expressi... | 10.1016/0169-328x(93)90015-h | 8,510,502 | D000818:Animals; D001921:Brain; D001923:Brain Chemistry; D002452:Cell Count; D004268:DNA-Binding Proteins; D051766:Early Growth Response Protein 1; D015870:Gene Expression; D017874:Immediate-Early Proteins; D007150:Immunohistochemistry; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012892:Sleep Deprivation... | Brain research. Molecular brain research | 1,993 | D004268:DNA-Binding Proteins; D051766:Early Growth Response Protein 1; C486110:Egr1 protein, rat; D017874:Immediate-Early Proteins; D014157:Transcription Factors |
Perceptual Evaluation for Multi-Exposure Image Fusion of Dynamic Scenes. | A common approach to high dynamic range (HDR) imaging is to capture multiple images of different exposures followed by multi-exposure image fusion (MEF) in either radiance or intensity domain. A predominant problem of this approach is the introduction of the ghosting artifacts in dynamic scenes with camera and object m... | 10.1109/TIP.2019.2940678 | 31,535,996 | IEEE transactions on image processing : a publication of the IEEE Signal Processing Society | 2,019 | ||
Long term sequelae from childhood pneumonia; systematic review and meta-analysis. | BACKGROUND
The risks of long term sequelae from childhood pneumonia have not been systematically assessed. The aims of this study were to: (i) estimate the risks of respiratory sequelae after pneumonia in children under five years; (ii) estimate the distribution of the different types of respiratory sequelae; and (iii)... | 10.1371/journal.pone.0031239 | 22,384,005 | D001249:Asthma; D029481:Bronchitis, Chronic; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008171:Lung Diseases; D008297:Male; D011014:Pneumonia; D012107:Research Design; D012306:Risk; D013997:Time Factors | PloS one | 2,012 | |
Aortic intracardiac echocardiography-guided septal puncture during mitral valvuloplasty. | AIMS
Transoesophageal echocardiography (TEE) and venous intracardiac echocardiography (ICE) are traditionally used to visualize the interatrial septum (IAS) and the tenting effect of the fossa ovalis in patients undergoing percutaneous balloon mitral valvuloplasty (PBMV). The aim of the present study was to assess the ... | 10.1093/ehjci/jet128 | 23,857,994 | D000328:Adult; D004452:Echocardiography; D005260:Female; D006346:Heart Septum; D006801:Humans; D008297:Male; D008875:Middle Aged; D008946:Mitral Valve Stenosis; D011446:Prospective Studies; D011677:Punctures; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional | European heart journal. Cardiovascular Imaging | 2,014 | |
Impact of Time Between Induction Chemotherapy and Complete Remission on Survival Outcomes in Patients With Acute Myeloid Leukemia. | BACKGROUND
The majority of patients with acute myeloid leukemia (AML) receive intensive induction chemotherapy for obtaining a complete remission (CR). Despite consolidation chemotherapy and advances in allogeneic hematopoietic stem cell transplantation, most of these patients finally relapse and die from AML. The aim ... | 10.1016/j.clml.2019.08.007 | 31,540,855 | D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D060828:Induction Chemotherapy; D015470:Leukemia, Myeloid, Acute; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016016:Proportional Hazards Models; D012074:Remission Induction; D012189:Retrospective Studies; D016019... | Clinical lymphoma, myeloma & leukemia | 2,019 | |
A molecular beacon and graphene oxide-based fluorescent biosensor for Cu(2+) detection. | In this work, we report a "turn-on" fluorescent strategy for the direct detection of Cu(2+) in solutions using molecular beacons (MBs) and graphene oxide (GO). MBs are special single-stranded DNA and carry fluorescence sources. GO is a new nanomaterial having remarkable physical properties. In the sensing system, GO wa... | 23,357,003 | D015374:Biosensing Techniques; D003300:Copper; D015342:DNA Probes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006108:Graphite; D015336:Molecular Probe Techniques; D010087:Oxides; D013050:Spectrometry, Fluorescence | Biosensors & bioelectronics | 2,013 | D015342:DNA Probes; D010087:Oxides; D006108:Graphite; D003300:Copper | |
Protection of BNT162b2 Vaccine Booster against Covid-19 in Israel. | BACKGROUND
On July 30, 2021, the administration of a third (booster) dose of the BNT162b2 messenger RNA vaccine (Pfizer-BioNTech) was approved in Israel for persons who were 60 years of age or older and who had received a second dose of vaccine at least 5 months earlier. Data are needed regarding the effect of the boos... | 10.1056/NEJMoa2114255 | 34,525,275 | D000368:Aged; D000369:Aged, 80 and over; D000090982:BNT162 Vaccine; D000086382:COVID-19; D000086663:COVID-19 Vaccines; D016208:Databases, Factual; D005260:Female; D006801:Humans; D007117:Immunization, Secondary; D007557:Israel; D008297:Male; D008875:Middle Aged; D062072:Patient Acuity; D016012:Poisson Distribution; D00... | The New England journal of medicine | 2,021 | D000086663:COVID-19 Vaccines; D000090982:BNT162 Vaccine |
Emergent dolutegravir resistance in integrase-naïve, treatment experienced patients from Zimbabwe. | We report two cases of dolutegravir (DTG) resistance in highly treatment experienced patients. Monitoring for treatment failure and adherence support is important in highly treatment experienced patients taking DTG.
What this study adds
Dolutegravir is the mainstay of HIV treatment programmes and emergence of drug re... | 10.4102/sajhivmed.v23i1.1435 | 36,479,423 | Southern African journal of HIV medicine | 2,022 | ||
CRISPR-Based Programmable Nucleic Acid-Binding Protein Technology Can Specifically Detect Fatal Tropical Disease-Causing Pathogens. | Diagnostic approaches capable of ultrasensitive pathogen detection from low-volume clinical samples, running without any sophisticated instrument and laboratory setup, are easily field-deployable, inexpensive, and rapid, and are considered ideal for monitoring disease progression and surveillance. However, standard pat... | 10.1155/2022/5390685 | 36,199,433 | Journal of tropical medicine | 2,022 | ||
Complementary DNA-DNA hybridization in Drosophila. | We have performed DNA-DNA hybridization experiments among several species of Drosophila using the evolutionarily conserved portion of the genome representing sequences coding for amino acids of proteins. This was done by using as tracer, radioactively labeled complementary DNA that was reverse transcribed from adult mR... | 10.1007/BF00182390 | 1,372,940 | D000818:Animals; D004247:DNA; D004330:Drosophila; D005260:Female; D008297:Male; D009693:Nucleic Acid Hybridization; D010802:Phylogeny; D012313:RNA | Journal of molecular evolution | 1,992 | D012313:RNA; D004247:DNA |
Disruption of USP9X in macrophages promotes foam cell formation and atherosclerosis. | Subendothelial macrophage internalization of modified lipids and foam cell formation are hallmarks of atherosclerosis. Deubiquitinating enzymes (DUBs) are involved in various cellular activities; however, their role in foam cell formation is not fully understood. Here, using a loss-of-function lipid accumulation screen... | 35,389,885 | D000818:Animals; D050197:Atherosclerosis; D005487:Foam Cells; D008077:Lipoproteins, LDL; D008264:Macrophages; D051379:Mice; D000074085:Mice, Knockout, ApoE; D043222:Ubiquitin Thiolesterase | The Journal of clinical investigation | 2,022 | D008077:Lipoproteins, LDL; D043222:Ubiquitin Thiolesterase; C404328:Usp9x protein, mouse | |
Evaluation of esterification routes for long chain cellulose esters. | Long chain cellulose esters are internally plasticized bio-based materials, which have good future potential in several applications such as coatings, films and plastics. The long chain cellulose esters with different side chain lengths were synthesized using different esterification methods. When homogeneous esterific... | 10.1016/j.heliyon.2019.e02898 | 31,799,468 | Heliyon | 2,019 | ||
Roles of mast cells and their interactions with the trigeminal nerve in migraine headache. | Migraine pain is characterized by an intense, throbbing pain in the head area and possesses complex pathological and physiological origins. Among the various factors believed to contribute to migraine are mast cells (MCs), resident tissue immune cells that are closely associated with pain afferents in the meninges. In ... | 10.1177/17448069231181358 | 37,232,078 | D006801:Humans; D008407:Mast Cells; D008881:Migraine Disorders; D014276:Trigeminal Nerve; D015740:Calcitonin Gene-Related Peptide; D010146:Pain; D051219:Pituitary Adenylate Cyclase-Activating Polypeptide | Molecular pain | 2,023 | D015740:Calcitonin Gene-Related Peptide; D051219:Pituitary Adenylate Cyclase-Activating Polypeptide |
Ageing in a collective: the impact of ageing individuals on social network structure. | Ageing affects many phenotypic traits, but its consequences for social behaviour have only recently become apparent. Social networks emerge from associations between individuals. The changes in sociality that occur as individuals get older are thus likely to impact network structure, yet this remains unstudied. Here we... | 10.1098/rstb.2022.0061 | 36,802,789 | D000818:Animals; D005260:Female; D008253:Macaca mulatta; D012919:Social Behavior; D000375:Aging; D012931:Social Environment; D060756:Social Networking | Philosophical transactions of the Royal Society of London. Series B, Biological sciences | 2,023 | |
The effect of omeprazole on gastric acidity and the absorption of liver cobalamins. | The effect of gastric anacidity on the absorption of food-bound cobalamins is uncertain. Omeprazole, an inhibitor of the enzyme H-K-ATPase in the parietal cell, is the most potent inhibitor of gastric acidity known so far. In 17 healthy male volunteers the absorption of liver-bound cobalamins was assessed after a singl... | 10.3109/00365528708991873 | 3,576,126 | D000042:Absorption; D000328:Adult; D005243:Feces; D005744:Gastric Acid; D006801:Humans; D007437:Intrinsic Factor; D008099:Liver; D008297:Male; D009853:Omeprazole; D014805:Vitamin B 12 | Scandinavian journal of gastroenterology | 1,987 | D007437:Intrinsic Factor; D009853:Omeprazole; D014805:Vitamin B 12 |
Predictors of low bone mineral density in the elderly: the role of dietary intake, nutritional status and sarcopenia. | OBJECTIVES
The aims of this study were to investigate the relationship between sarcopenia, dietary intake, nutritional indices and hip bone mineral density (BMD) in the elderly, and to estimate the risk of low BMD due to specific independent predictor thresholds.
SUBJECTS AND METHODS
Body mass index (BMI), serum albu... | 10.1038/sj.ejcn.1602779 | 17,637,603 | D015502:Absorptiometry, Photon; D000368:Aged; D000375:Aging; D015992:Body Mass Index; D015519:Bone Density; D004044:Dietary Proteins; D002149:Energy Intake; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D009133:Muscular Atrophy; D015596:Nutrition Assessment; D009752:Nutritional Status; D010024:... | European journal of clinical nutrition | 2,008 | D004044:Dietary Proteins; D012709:Serum Albumin |
Association between social support and mutual-support needs among the rural adults in China: a cross-sectional study. | Background
In rural China, there is now a huge gap between the supply and demand for old-age care. To close the gap, developing rural mutual old-age services is extremely important. The purpose of this study is to clarify the relationship among social support, mutual support need, and mutual support willingness.
Meth... | 10.3389/fpubh.2023.1171046 | 37,333,532 | D006801:Humans; D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D006304:Health Status; D002681:China; D012424:Rural Population; D012944:Social Support | Frontiers in public health | 2,023 | |
The Future of Atopic Dermatitis Treatment. | In recent years, there has been a growing movement towards the use of targeted therapies in treating of atopic dermatitis (AD), parallel to that which has occurred in psoriasis. Among the systemic medications being studied are subcutaneous or intravenously administered biologic drugs targeting specific molecules such a... | 10.1007/978-3-319-64804-0_15 | 29,063,440 | D000982:Antipruritics; D003876:Dermatitis, Atopic; D055808:Drug Discovery; D006801:Humans | Advances in experimental medicine and biology | 2,017 | D000982:Antipruritics |
Functional impairment of hematopoietic progenitor cells in patients with coronary heart disease. | The circulating form of endothelial progenitors cells (EPCs) are derived from bone marrow (BM)-derived hematopoietic stem cells (HSCs). Enhanced mobilization of EPCs was shown to be linked to cardiac diseases. This study investigated whether reduced EPC levels in advanced coronary heart disease (CHD) are secondary to a... | 10.1111/j.1600-0609.2007.01007.x | 18,081,701 | D000368:Aged; D000369:Aged, 80 and over; D001854:Bone Marrow Cells; D002465:Cell Movement; D002478:Cells, Cultured; D003114:Colony-Forming Units Assay; D003327:Coronary Disease; D004730:Endothelium, Vascular; D006412:Hematopoietic Stem Cells; D006801:Humans; D007963:Leukocytes, Mononuclear; D008297:Male; D008875:Middle... | European journal of haematology | 2,008 | D042461:Vascular Endothelial Growth Factor A |
Effect of temperature on cuticular transpiration of isolated cuticular membranes and leaf discs. | Cuticular transpiration was measured in the temperature range between 10 degrees C and 55 degrees C using tritiated water and five species (Vinca major L., Prunus laurocerasus L., Forsythia intermedia L., Citrus aurantium L., and Hedera helix L.). Cuticular water permeabilities measured with isolated cuticular membrane... | 10.1093/jexbot/52.362.1893 | 11,520,878 | D002462:Cell Membrane; D004734:Energy Metabolism; D006358:Hot Temperature; D066298:In Vitro Techniques; D007700:Kinetics; D019684:Magnoliopsida; D010539:Permeability; D019441:Plant Epidermis; D018515:Plant Leaves; D018526:Plant Transpiration; D013696:Temperature; D014316:Tritium; D014867:Water | Journal of experimental botany | 2,001 | D014867:Water; D014316:Tritium |
Applications of omics and nanotechnology to improve pig embryo production in vitro. | An appropriate environment to optimize porcine preimplantation embryo production in vitro is required as genetically modified pigs have become indispensable for biomedical research and agriculture. To provide suitable culture conditions, omics technologies have been applied to elucidate which metabolic substrates and p... | 10.1002/mrd.23260 | 31,478,591 | D000818:Animals; D019976:Cloning, Organism; D004622:Embryo, Mammalian; D044127:Epigenesis, Genetic; D057890:Epigenomics; D020869:Gene Expression Profiling; D018507:Gene Expression Regulation, Developmental; D055432:Metabolomics; D036103:Nanotechnology; D013552:Swine | Molecular reproduction and development | 2,019 | |
What is the acceptance of video consultations among orthopedic and trauma outpatients? A multi-center survey in 780 outpatients. | INTRODUCTION
The purpose of the present study was to assess orthopedic and orthopedic trauma patients' willingness to perform hypothetical remote video consultations, possible advantages as well as concerns.
METHODS
Between June 2019 and November 2019, a survey amongst consecutive regular orthopedic and orthopedic tr... | 10.1016/j.injury.2021.02.023 | 33,648,741 | D000293:Adolescent; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009985:Orthopedics; D010045:Outpatients; D058873:Pandemics; D019114:Remote Consultation; D011795:Surveys and Questionnaires | Injury | 2,021 | |
Congenital Internal Jugular Phlebectasia: An Anomaly Still Poorly Recognized. | Congenital internal jugular phlebectasia (CIJP) is a rare condition characterized by congenital dilatation of the vein without tortuosity that becomes more evident during straining as a lateral neck mass. CIJP often remains undiagnosed from a few months to several years after the onset of the swelling. It is frequently... | 10.1055/a-2130-3269 | 37,663,067 | European journal of pediatric surgery reports | 2,023 | ||
α-amylase crystalloid granuloma of the parotid gland: case report and review of the literature. | We report a case of α-amylase crystalloid granuloma of the parotid gland in a 65-year-old Japanese woman. Histopathologically, the lesion comprised cystlike dilatation of the ducts and foreign body granulomas, with deposits of numerous crystalloid structures. The crystalloids were eosinophilic and varied in size and sh... | 22,749,708 | D000368:Aged; D005260:Female; D006099:Granuloma; D006801:Humans; D007150:Immunohistochemistry; D008855:Microscopy, Electron, Scanning; D016612:Paraffin Embedding; D010307:Parotid Neoplasms; D011859:Radiography; D000516:alpha-Amylases | Oral surgery, oral medicine, oral pathology and oral radiology | 2,012 | D000516:alpha-Amylases | |
Association between vitamin D and ovarian cancer development in BRCA1 mutation carriers. | OBJECTIVE
Women with inherited mutations in BRCA1 gene have a high (40-70%) genetic risk of developing ovarian cancer. Epidemiological studies suggest an inverse correlation between serum vitamin D (VD) levels and the risk of ovarian cancer, but there is a lack of data from BRCA1 mutation (BRCA1 mut) carriers. Therefor... | 10.18632/oncotarget.27803 | 33,227,068 | Oncotarget | 2,020 | ||
[New Method for Evaluating the Substrate Efficiency of Modified Deoxynucleoside Triphosphates for Selex]. | A new method for evaluating the substrate efficiency of deoxynucleoside triphosphates containing functional groups for the selection of modified aptamers (mod-SELEX) is proposed. The method involves conducting three consecutive rounds of PCR with a combinatorial library and a modified dNTP candidate for mod-SELEX. The ... | 10.31857/S0026898422030090 | 35,621,110 | D052157:Aptamers, Nucleotide; D015723:Gene Library; D011122:Polyphosphates; D052156:SELEX Aptamer Technique | Molekuliarnaia biologiia | 2,022 | D052157:Aptamers, Nucleotide; D011122:Polyphosphates; C005692:triphosphoric acid |
The Effect of a Strength and Conditioning Protocol on NCAA Division 1 Women's Basketball Players' Mental Toughness. | Mental toughness (MT) is a popularized term in sports since it has been found to be positively related to performance. Self-assessment is the most common method of MT data collection. In the strength and conditioning (S&C) context, MT research has focused on males with a notable lack of female participants. Division 1 ... | 37,122,764 | International journal of exercise science | 2,023 | |||
Targeted delivery of emamectin benzoate by functionalized polysuccinimide nanoparticles for the flowering cabbage and controlling Plutella xylostella. | BACKGROUND
Plutella xylostella, one of the most destructive and cosmopolitan pests of cruciferous crops, is especially harmful to the young tissues of the flowering cabbage (Brassica campestris L.). Although emamectin benzoate (EB) has high insecticidal activity against P. xylostella, one major reason of low utilizatio... | 10.1002/ps.6689 | 34,689,392 | D000818:Animals; D001224:Aspartic Acid; D001937:Brassica; D007306:Insecticides; D007559:Ivermectin; D007814:Larva; D007915:Lepidoptera; D009036:Moths; D053758:Nanoparticles | Pest management science | 2,022 | D007306:Insecticides; C025252:poly-DL-succinimide; D001224:Aspartic Acid; D007559:Ivermectin; C108024:emamectin benzoate |
Light Controlled Nanobiohybrids for Modulating Chiral Alcohol Synthesis. | The modulation of whole-cell activity presents a considerable challenge in biocatalysis. Conventional approaches to whole-cell catalysis, while having their strengths, often rely on complex and deliberate enzyme designs, which could result in difficulties in activity modulation and prolonged response times. Additionall... | 10.1007/s12010-023-04667-8 | 37,594,649 | Applied biochemistry and biotechnology | 2,023 | ||
Update in the management of gastric varices. | PURPOSE OF REVIEW
This article discusses the most recent studies regarding the management of gastric varices.
RECENT FINDINGS
New case series and meta-analyses have increased our understanding of the endoscopic and endovascular treatment options for patients with gastric varices, including the use of cyanoacrylates, ... | 10.1097/MOG.0000000000000267 | 27,054,775 | D021721:Balloon Occlusion; D016099:Endoscopy, Gastrointestinal; D019160:Endosonography; D057510:Endovascular Procedures; D004932:Esophageal and Gastric Varices; D006801:Humans | Current opinion in gastroenterology | 2,016 | |
α-Glucosidase inhibition activity and in silico study of 2-(benzo[d][1,3]dioxol-5-yl)-4H-chromen-4-one, a synthetic derivative of flavone. | A synthetic flavone derivative 2-(benzo[d][1,3]dioxol-5-yl)-4H-chromen-4-one (BDC) was synthesized by the one pot reaction method and assessed for α-glucosidase inhibitory activity. The BDC demonstrated dose dependent inhibition of α-glucosidase activity. A maximum inhibition (99.3 ± 0.26%) of α-glucosidase was observe... | 10.1016/j.bmc.2018.12.021 | 30,594,450 | D052117:Benzodioxoles; D001578:Benzopyrans; D020134:Catalytic Domain; D047309:Flavones; D065089:Glycoside Hydrolase Inhibitors; D007004:Hypoglycemic Agents; D007700:Kinetics; D062105:Molecular Docking Simulation; D011485:Protein Binding; D000520:alpha-Glucosidases | Bioorganic & medicinal chemistry | 2,019 | D052117:Benzodioxoles; D001578:Benzopyrans; D047309:Flavones; D065089:Glycoside Hydrolase Inhibitors; D007004:Hypoglycemic Agents; D000520:alpha-Glucosidases |
A Bayesian approach to assessing small-study effects in meta-analysis of a binary outcome with controlled false positive rate. | Publication bias threatens meta-analysis validity. It is often assessed via the funnel plot; an asymmetric plot implies small-study effects, and publication bias is one cause of the asymmetry. Egger's regression test is a widely used tool to quantitatively assess such asymmetry. It examines the association between the ... | 10.1002/jrsm.1415 | 32,424,987 | D001499:Bayes Theorem; D005189:False Positive Reactions; D006801:Humans; D015201:Meta-Analysis as Topic; D016017:Odds Ratio; D017594:Publication Bias; D012044:Regression Analysis; D015203:Reproducibility of Results; D012107:Research Design; D016896:Treatment Outcome | Research synthesis methods | 2,020 | |
Stem water transport of Lithocarpus edulis, an evergreen oak with radial-porous wood. | The stem water conducting system of an evergreen broad-leaved oak, Lithocarpus edulis (Mak.) Nakai, was investigated. Evergreen broad-leaved oaks (Lithocarpus, Castanopsis, Cyclobalanopsis, Quercus) belonging to the Quercoideae are a major component of Asian monsoon forests, and are characterized by the possession of r... | 10.1093/treephys/25.2.221 | 15,574,403 | D018515:Plant Leaves; D018547:Plant Stems; D029963:Quercus; D014197:Trees; D014867:Water; D014934:Wood; D052584:Xylem | Tree physiology | 2,005 | D014867:Water |
Glycosaminoglycan sulphation affects the seeded misfolding of a mutant prion protein. | BACKGROUND
The accumulation of protease resistant conformers of the prion protein (PrP(res)) is a key pathological feature of prion diseases. Polyanions, including RNA and glycosaminoglycans have been identified as factors that contribute to the propagation, transmission and pathogenesis of prion disease. Recent studie... | 10.1371/journal.pone.0012351 | 20,808,809 | D000818:Animals; D002460:Cell Line; D002474:Cell-Free System; D006025:Glycosaminoglycans; D006497:Heparitin Sulfate; D051379:Mice; D050505:Mutant Proteins; D009154:Mutation; D009696:Nucleic Acids; D017096:Prion Diseases; D011328:Prions; D017510:Protein Folding; D055672:Static Electricity; D013431:Sulfates | PloS one | 2,010 | D006025:Glycosaminoglycans; D050505:Mutant Proteins; D009696:Nucleic Acids; D011328:Prions; D013431:Sulfates; D006497:Heparitin Sulfate |
Synthesis and bioactivity evaluation of rhodanine derivatives as potential anti-bacterial agents. | Five series of (Z)-5-(4-(2-oxo-2-phenylethoxy)benzylidene)-2-thioxothiazolidin-4-one derivatives (I-V) were synthesized, characterized, and evaluated for their anti-bacterial activity. Most of the synthesized compounds showed potent inhibition against several Gram-positive bacteria (including multidrug-resistant clinic... | 10.1016/j.ejmech.2012.05.023 | 22,703,706 | D000900:Anti-Bacterial Agents; D060326:Chemistry Techniques, Synthetic; D018432:Drug Resistance, Multiple; D055624:Methicillin-Resistant Staphylococcus aureus; D008826:Microbial Sensitivity Tests; D015363:Quinolones; D012236:Rhodanine | European journal of medicinal chemistry | 2,012 | D000900:Anti-Bacterial Agents; D015363:Quinolones; D012236:Rhodanine |
Serum and urine electrolytes in primigravid Africans during pregnancy and postnatal period. | Serum and urine electrolyte changes were studied in 55 primigravid African women during pregnancy and the postnatal period. The findings suggest that there is a fall in the serum sodium in the first trimester, which is followed by a gradual and steady rise throughout pregnancy. The serum potassium did not show any cons... | 10.1016/0009-8981(78)90512-0 | 719,896 | D044383:Black People; D002712:Chlorides; D005260:Female; D006801:Humans; D011188:Potassium; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D012964:Sodium | Clinica chimica acta; international journal of clinical chemistry | 1,978 | D002712:Chlorides; D012964:Sodium; D011188:Potassium |
Sodium butyrate-induced structural and functional modifications in proteins of cultured rabbit articular chondrocytes. | The effects of sodium butyrate (NaB), a potent growth inhibitory agent, on actin distribution, alkaline phosphatase (AP) activity and protein content were studied in rabbit articular chondrocytes in monolayer culture. When growth of randomly proliferating cells was arrested with NaB, actin stress fibers appeared; at th... | 2,731,193 | D000469:Alkaline Phosphatase; D000818:Animals; D002087:Butyrates; D020148:Butyric Acid; D002358:Cartilage, Articular; D002478:Cells, Cultured; D003599:Cytoskeleton; D011506:Proteins; D011817:Rabbits | Cellular and molecular biology | 1,989 | D002087:Butyrates; D011506:Proteins; D020148:Butyric Acid; D000469:Alkaline Phosphatase | |
[Experimental study on xiaoliu pingyi mixture with medicated serum in inducing apoptosis of human hepatocellular carcinoma cell line H-7402]. | OBJECTIVE
To observe the efficacy of Xiaoliu Pingyi Mixture (XLPY) in inducing the apoptosis of human hepatocellular carcinoma (HCC) cell line H-7402.
METHODS
Using serum pharmacologic method, the morphological change of apoptotic cells was observed at different time points by co-culturing with different concentratio... | 12,575,558 | D000818:Animals; D000972:Antineoplastic Agents, Phytogenic; D017209:Apoptosis; D006528:Carcinoma, Hepatocellular; D018920:Coculture Techniques; D004365:Drugs, Chinese Herbal; D006801:Humans; D008113:Liver Neoplasms; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D014407:Tumor Cells, Cultured | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine | 2,001 | D000972:Antineoplastic Agents, Phytogenic; D004365:Drugs, Chinese Herbal | |
Adaptive-optics compensation by distributed beacons for non-kolmogorov turbulence. | In optical propagation through atmospheric turbulence, the performance of compensation with adaptive optics depends on a beacon's spatial distribution. With distributed beacons, the inefficiency of the modal correction, which is defined as the ratio of the anisoplanatic error of the jth mode and the Zernike-coefficient... | 10.1364/ao.40.003441 | 18,360,369 | Applied optics | 2,001 |
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