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[Effect of fluoride on the expression of MMP-20/TIMP-2 in ameloblast of rat incisor and the antagonistic effect of melatonin against fluorosis]. | PURPOSE
To study the effect of concentration of fluoride on the expression of matrix metalloproteinase-20(MMP-20) and tissue inhibitors of metalloproteinase-2 (TIMP-2) in the ameloblast of rat incisor,and explore the formation mechanism of dental fluorosis. By comparing the different expression of MMP-20,TIMP-2 between... | 21,451,891 | D000565:Ameloblasts; D053523:Amelogenin; D000818:Animals; D003743:Dental Enamel; D005459:Fluorides; D009050:Fluorosis, Dental; D007180:Incisor; D053519:Matrix Metalloproteinase 20; D008550:Melatonin; D010710:Phosphates; D051381:Rats; D017208:Rats, Wistar; D019716:Tissue Inhibitor of Metalloproteinase-2 | Shanghai kou qiang yi xue = Shanghai journal of stomatology | 2,011 | D053523:Amelogenin; D010710:Phosphates; D019716:Tissue Inhibitor of Metalloproteinase-2; C012980:fluorophosphate; D053519:Matrix Metalloproteinase 20; D008550:Melatonin; D005459:Fluorides | |
Tumor stiffness measured by quantitative and qualitative shear wave elastography of breast cancer. | OBJECTIVE
To correlate clinicoradiologic and pathological features of breast cancer with quantitative and qualitative shear wave elastographic parameters.
METHODS
82 breast cancers in 75 patients examined by B-mode ultrasound and shear wave elastography (SWE) were included. SWE parameters including quantitative facto... | 10.1259/bjr.20170830 | 29,557,217 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014408:Biomarkers, Tumor; D001943:Breast Neoplasms; D054459:Elasticity Imaging Techniques; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D012189:Retrospective Studies; D016217:Ultrasonography, Mammary | The British journal of radiology | 2,018 | D014408:Biomarkers, Tumor |
The complete mitochondrial genome sequence of Zhuanghe Big-boned chicken (Gallus gallus). | In this study, the complete mitochondrial genome of Zhuanghe Big-boned chicken (Gallus gallus) was obtained by using next generation sequencing method. The complete mitogenome sequence is 16,784 bp in length, containing 13 protein-coding genes, 2 ribosomal RNAs, 22 transfer RNA genes, and one control region. This work ... | 10.1080/23802359.2020.1785351 | 33,457,891 | Mitochondrial DNA. Part B, Resources | 2,020 | ||
Novel lipid combination for delivery of plasmid DNA to immune cells in the spleen. | This study reports on the development of a novel lipid combination that permits the efficient and highly selective delivery of plasmid DNA (pDNA) to immune cells in the spleen. Using DODAP, an ionizable lipid that was previously thought to be inefficient for gene delivery, we show for the first time, that this ignored ... | 10.1016/j.jconrel.2021.01.005 | 33,422,500 | D004247:DNA; D008055:Lipids; D053758:Nanoparticles; D010957:Plasmids; D013154:Spleen; D014162:Transfection | Journal of controlled release : official journal of the Controlled Release Society | 2,021 | D008055:Lipids; D004247:DNA |
Measuring the depth of reflection in reflective supervision/consultation sessions: Initial validation of the Reflective Interaction Observation Scale (RIOS). | Research on reflective supervision and reflective consultation (RS/C) is limited, and has primarily relied on self-report measures and qualitative interviews. To our knowledge, no measures currently exist which provide a way to observationally measure what occurs during an RS/C session. Thus, the Reflective Interaction... | 10.1002/imhj.21939 | 34,390,008 | D006282:Health Personnel; D006801:Humans; D012017:Referral and Consultation; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires | Infant mental health journal | 2,022 | |
Peripheral magnetic theta burst stimulation to muscles can effectively reduce spasticity: a randomized controlled trial. | BACKGROUND
Spasticity is a common complication of many neurological diseases and despite contributing much disability; the available therapeutic options are limited. Peripheral magnetic stimulation is one promising option. In this study, we investigated whether peripheral intermittent theta burst stimulation (piTBS) wi... | 10.1186/s12984-022-00985-w | 35,034,653 | D019274:Botulinum Toxins, Type A; D006801:Humans; D060328:Magnetic Phenomena; D009128:Muscle Spasticity; D009132:Muscles; D020521:Stroke; D050781:Transcranial Magnetic Stimulation; D016896:Treatment Outcome | Journal of neuroengineering and rehabilitation | 2,022 | D019274:Botulinum Toxins, Type A |
Taurine modulates antioxidant potential and controls lipid peroxidation in the aorta of high fructose-fed rats. | High dosage of fructose induces insulin resistance, glucose intolerance and alterations in plasma lipid profile in normal rats. Recently, it has been shown that these rats also develop oxidative stress, which plays a prominent role in diabetic pathology. We now report the effect of taurine on the susceptibility of the ... | 10.1080/10258140290027261 | 12,186,769 | D000818:Animals; D000975:Antioxidants; D001013:Aorta, Thoracic; D001205:Ascorbic Acid; D005632:Fructose; D007333:Insulin Resistance; D015227:Lipid Peroxidation; D008054:Lipid Peroxides; D008062:Lipofuscin; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013438:Sulfhydryl Compounds; D013654:Taurine; D017392:Thiobarbi... | Journal of biochemistry, molecular biology, and biophysics : JBMBB : the official journal of the Federation of Asian and Oceanian Biochemists and Molecular Biologists (FAOBMB) | 2,002 | D000975:Antioxidants; D008054:Lipid Peroxides; D008062:Lipofuscin; D013438:Sulfhydryl Compounds; D017392:Thiobarbituric Acid Reactive Substances; D014810:Vitamin E; D013654:Taurine; D005632:Fructose; D001205:Ascorbic Acid |
Fresh vegetables and ready-to eat salads: phenotypic characterization of moulds and molecular characterization of yeasts. | This study was performed to characterize and quantify mould and yeast isolates in fresh vegetables (FV) and ready to eat salads (RTES). During 2007, a random set of 194 samples, including 56 samples of FV and 138 samples of RTES, were analyzed for a total of 388 mycological determinations. Yeasts and moulds identificat... | 22,913,173 | D005516:Food Microbiology; D005658:Fungi; D058889:Molecular Typing; D016533:Mycological Typing Techniques; D010641:Phenotype; D014675:Vegetables; D015003:Yeasts | Annali di igiene : medicina preventiva e di comunita | 2,012 | ||
Brazilian external occupational dose management system. | Brazil, a large country, with more than 120,000 workers under individual monitoring for ionising radiation, developed, more than 20 y ago, a centralised data bank for external occupational dose. This old database, however, presented some problems and does not satisfy any more Brazilian present needs, not allowing dose ... | 10.1093/rpd/ncq411 | 21,147,785 | D001938:Brazil; D003199:Computer Systems; D016208:Databases, Factual; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D016273:Occupational Exposure; D011834:Radiation Monitoring; D011835:Radiation Protection; D011839:Radiation, Ionizing; D011874:Radiometry; D012042:Registries | Radiation protection dosimetry | 2,011 | |
Fishing for causes and cures of motor neuron disorders. | Motor neuron disorders (MNDs) are a clinically heterogeneous group of neurological diseases characterized by progressive degeneration of motor neurons, and share some common pathological pathways. Despite remarkable advances in our understanding of these diseases, no curative treatment for MNDs exists. To better unders... | 10.1242/dmm.015719 | 24,973,750 | D000818:Animals; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D006801:Humans; D016472:Motor Neuron Disease; D015398:Signal Transduction; D015027:Zebrafish | Disease models & mechanisms | 2,014 | |
Blockade of the hypothalamic-pituitary-testicular axis with a GnRH antagonist in the neonatal marmoset monkey: changes in Leydig cell ultrastructure. | Little is known of the cell biology of Leydig cells during the neonatal activation of the hypothalamic-pituitary-testicular (HPT) axis. The current study examined the effect of blockade of the HPT axis with a GnRH antagonist (antide) on the neonatal population of Leydig cells in the new world primate, the common marmos... | 10.1016/s0040-8166(98)80084-0 | 10,036,790 | D000818:Animals; D000831:Animals, Newborn; D001284:Atrophy; D002144:Callithrix; D002784:Cholesterol; D018871:Endoplasmic Reticulum, Smooth; D007987:Gonadotropin-Releasing Hormone; D006065:Gonadotropins, Pituitary; D007006:Hypogonadism; D007030:Hypothalamo-Hypophyseal System; D007985:Leydig Cells; D008297:Male; D008830:... | Tissue & cell | 1,998 | D006065:Gonadotropins, Pituitary; D009842:Oligopeptides; D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; C057022:iturelix; D002784:Cholesterol |
Robust Flexible Preserving Embedding. | Neighborhood preserving embedding (NPE) has been proposed to encode overall geometry manifold embedding information. However, the class-special structure of the data is destroyed by noise or outliers existing in the data. To address this problem, in this article, we propose a novel embedding approach called robust flex... | 10.1109/TCYB.2019.2953922 | 31,831,459 | IEEE transactions on cybernetics | 2,020 | ||
Regional and demographic variations of Carotid artery Intima and Media Thickness (CIMT): A Systematic review and meta-analysis. | BACKGROUND AND OBJECTIVE
Carotid artery intima media thickness (CIMT) is a strong predictor of Coronary Heart Disease (CHD) and independent phenotype of early atherosclerosis. The global variation of CIMT and its demographic association is yet unclear. We evaluated regional variations of CIMT based on WHO regions and a... | 10.1371/journal.pone.0268716 | 35,819,948 | D050197:Atherosclerosis; D002339:Carotid Arteries; D059168:Carotid Intima-Media Thickness; D003327:Coronary Disease; D003710:Demography; D005260:Female; D006801:Humans; D008297:Male | PloS one | 2,022 | |
Assessing the immune response to SARS-CoV-2 mRNA vaccines in siponimod-treated patients: a nonrandomized controlled clinical trial (AMA-VACC). | Background
Systematic data are lacking on the immune response toward SARS-CoV-2 mRNA vaccination in SPMS patients on disease-modifying therapies (DMTs).
Objective
The AMA-VACC clinical trial was designed to characterize immune responses to SARS-CoV-2 mRNA vaccines in siponimod-treated SPMS patients.
Design
AMA-VACC... | 10.1177/17562864221135305 | 36,381,503 | Therapeutic advances in neurological disorders | 2,022 | ||
The Association of Sanitation and Hygiene Practices With Intestinal Parasitic Infections Among Under-14 Children in Rural Dire Dawa, Eastern Ethiopia: A Community Based Cross-sectional Study. | Background
Intestinal parasitic infections (IPIs) are neglected tropical diseases. Sanitation and hygiene are vital components for achieving sustainable control of intestinal parasitic infections. Children are the most vulnerable to intestinal parasitic infections because of their immature immune systems and frequent e... | 10.1177/11786302231180801 | 37,362,236 | Environmental health insights | 2,023 | ||
Scanning image detection (SID) system for conventional transmission electron microscope (CTEM) images. | A new image detection system has been developed to display transmission electron microscope (TEM) images on a CRT without a video camera system. Deflection coils placed in both the upper space of an objective lens and in the lower space of the first intermediate lens scan a small electron probe simultaneously. The elec... | 10.1002/jemt.1060150409 | 2,391,565 | D007091:Image Processing, Computer-Assisted; D008277:Magnesium Oxide; D008854:Microscopy, Electron | Journal of electron microscopy technique | 1,990 | D008277:Magnesium Oxide |
Kidney preservation by bone marrow cell transplantation in hereditary nephropathy. | The prospect of cell-based therapy for kidney disease remains controversial despite its immense promise. We had previously shown that transplanting bone marrow and hematopoietic stem cells could generate renal cells and lead to the preservation of kidney function in a mouse model for cystinosis (Ctns(-/-)) that develop... | 10.1038/ki.2010.537 | 21,248,718 | D000469:Alkaline Phosphatase; D026921:Amino Acid Transport Systems, Neutral; D000818:Animals; D015415:Biomarkers; D016026:Bone Marrow Transplantation; D002454:Cell Differentiation; D002478:Cells, Cultured; D002908:Chronic Disease; D003404:Creatinine; D003545:Cysteine; D003554:Cystinosis; D004195:Disease Models, Animal;... | Kidney international | 2,011 | D026921:Amino Acid Transport Systems, Neutral; D015415:Biomarkers; D010710:Phosphates; C534463:cystinosin protein, mouse; C485184:enhanced green fluorescent protein; D049452:Green Fluorescent Proteins; D014508:Urea; D003404:Creatinine; D000469:Alkaline Phosphatase; D003545:Cysteine |
DYRK1B-STAT3 Drives Cardiac Hypertrophy and Heart Failure by Impairing Mitochondrial Bioenergetics. | BACKGROUND
Heart failure is a global public health issue that is associated with increasing morbidity and mortality. Previous studies have suggested that mitochondrial dysfunction plays critical roles in the progression of heart failure; however, the underlying mechanisms remain unclear. Because kinases have been repor... | 10.1161/CIRCULATIONAHA.121.055727 | 35,235,343 | D000818:Animals; D006332:Cardiomegaly; D004734:Energy Metabolism; D006333:Heart Failure; D006801:Humans; D051379:Mice; D018345:Mice, Knockout; D008928:Mitochondria; D009206:Myocardium; D032383:Myocytes, Cardiac; D017346:Protein Serine-Threonine Kinases; D011505:Protein-Tyrosine Kinases; D050796:STAT3 Transcription Fact... | Circulation | 2,022 | D050796:STAT3 Transcription Factor; C494086:STAT3 protein, human; D011505:Protein-Tyrosine Kinases; D017346:Protein Serine-Threonine Kinases |
Cardenolide Increase in Foxglove after 2,1,3-Benzothiadiazole Treatment Reveals a Potential Link between Cardenolide and Phytosterol Biosynthesis. | Cardenolides are steroidal metabolites in Digitalis lanata with potent cardioactive effects on animals. In plants, cardenolides are likely involved in various stress responses. However, the molecular mechanism of cardenolide increase during stresses is mostly unknown. Additionally, cardenolides are proposed to arise fr... | 10.1093/pcp/pcac144 | 36,222,367 | D000818:Animals; D004070:Digitalis; D002298:Cardenolides; D010840:Phytosterols; D010802:Phylogeny; D010088:Oxidoreductases | Plant & cell physiology | 2,023 | D002298:Cardenolides; C015700:benzo-1,2,3-thiadiazole; D010840:Phytosterols; D010088:Oxidoreductases |
Induction of the acute-phase reactant, alpha 1-acid glycoprotein, by glucocorticoids in rat hepatoma cells. | alpha 1-acid glycoprotein (alpha 1-AGP), or orosomucoid, is shown to be inducible by glucocorticoids in HTC rat hepatoma cells. Immunoprecipitation of [35S]methionine pulse-labeled proteins from these cells reveals secreted proteins of Mr = 35,000-48,000 (alpha 1-AGP) and Mr greater than 180,000, both of which are grea... | 10.1089/dna.1983.2.205 | 6,139,269 | D000818:Animals; D002460:Cell Line; D003513:Cycloheximide; D003907:Dexamethasone; D005786:Gene Expression Regulation; D005938:Glucocorticoids; D008114:Liver Neoplasms, Experimental; D009961:Orosomucoid; D011374:Progesterone; D012333:RNA, Messenger; D051381:Rats; D011965:Receptors, Glucocorticoid; D014444:Tyrosine Trans... | DNA (Mary Ann Liebert, Inc.) | 1,983 | D005938:Glucocorticoids; D009961:Orosomucoid; D012333:RNA, Messenger; D011965:Receptors, Glucocorticoid; D011374:Progesterone; D003907:Dexamethasone; D003513:Cycloheximide; D014444:Tyrosine Transaminase |
Hepatitis C virus and death risk in hemodialysis patients. | In maintenance hemodialysis (MHD) patients, hepatitis C virus (HCV) infection is common and may be associated with poor clinical outcomes. It was hypothesized that HCV infection would be associated with high all-cause and cardiovascular mortality in these patients after controlling for demographic and clinical characte... | 10.1681/ASN.2006070736 | 17,429,053 | D000328:Adult; D000368:Aged; D015331:Cohort Studies; D005260:Female; D016174:Hepacivirus; D006526:Hepatitis C; D006801:Humans; D007676:Kidney Failure, Chronic; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D013997:Time Factors | Journal of the American Society of Nephrology : JASN | 2,007 | |
Self-management and self-efficacy of women with gestational diabetes mellitus: a systematic review. | BACKGROUND
Gestational diabetes mellitus (GDM) is a temporary form of diabetes induced by pregnancy and is potentially harmful to both the mother and fetus The impact of GDM diagnosis on pregnant women needs to be taken into account. This is related to the capacity for self-management of GDM, for which quality evidence... | 10.1080/16549716.2022.2087298 | 35,867,537 | D016640:Diabetes, Gestational; D004032:Diet; D005260:Female; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D020377:Self Efficacy; D000073278:Self-Management | Global health action | 2,022 | |
Catalytic and enantioselective aza-ene and hetero-Diels-Alder reactions of alkenes and dienes with azodicarboxylates. | Lewis acids such as Cu(OTf)(2), Zn(OTf)(2), Yb(OTf)(3) and Nd(OTf)(3) catalyze the aza-ene reaction of alkenes with azodicarboxylates, giving the allylic amination adducts. The use of bis(2,2,2-trichloroethyl)azodicarboxylate as the amination reagent and Cu(OTf)(2) and Yb(OTf)(3) as the catalysts gave the aza-ene react... | 10.1039/b503744a | 16,010,370 | Organic & biomolecular chemistry | 2,005 | ||
Coexistent digital gouty and infective flexor tenosynovitis. | Flexor tenosynovitis of the hand is often caused by trauma or infection. Gouty tenosynovitis is an uncommon presentation of the condition and is usually misdiagnosed as infection with the patient undergoing surgery. The coexistence of infection and gout causing flexor tenosynovitis has never been described before in th... | 27,358,092 | D000493:Allopurinol; D003078:Colchicine; D005385:Fingers; D006073:Gout; D006074:Gout Suppressants; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D013203:Staphylococcal Infections; D013211:Staphylococcus aureus; D013717:Tenosynovitis; D016896:Treatment Outcome | BMJ case reports | 2,016 | D006074:Gout Suppressants; D000493:Allopurinol; D003078:Colchicine | |
Long-Term Safety and Effectiveness of Erenumab in Patients with Migraine: A Systematic Review and Single-Arm Meta-analysis. | BACKGROUND AND OBJECTIVE
Several studies on use of erenumab for migraine treatment have been published over recent years. However, its long-term safety and effectiveness have not been consistently established in the literature yet. We aimed to perform a qualitative and quantitative analysis of the long-term safety and ... | 10.1007/s40261-022-01230-x | 36,482,037 | D006801:Humans; D000077221:Calcitonin Gene-Related Peptide Receptor Antagonists; D008881:Migraine Disorders; D061067:Antibodies, Monoclonal, Humanized | Clinical drug investigation | 2,023 | C000605816:erenumab; D000077221:Calcitonin Gene-Related Peptide Receptor Antagonists; D061067:Antibodies, Monoclonal, Humanized |
Effect of polysorbate 80 on the intranasal absorption and brain distribution of tetramethylpyrazine phosphate in rats. | Drug delivery to the brain is limited by the blood-brain barrier (BBB). Intranasal delivery is a non-invasive route of drug administration which can bypass the BBB and contributed to a direct and rapid transport of drugs to the brain. However, intrinsic drug distribution to the brain after intranasal administration may... | 10.1007/s13346-018-0580-y | 30,168,052 | D000281:Administration, Intranasal; D061605:Administration, Intravenous; D000818:Animals; D001682:Biological Availability; D001774:Blood Chemical Analysis; D001812:Blood-Brain Barrier; D001923:Brain Chemistry; D004339:Drug Compounding; D016503:Drug Delivery Systems; D005240:Feasibility Studies; D008297:Male; D065588:Na... | Drug delivery and translational research | 2,019 | D011136:Polysorbates; D011719:Pyrazines; C017953:tetramethylpyrazine |
Stage-specific binding of inhibin and activin to subpopulations of rat germ cells. | Flow cytometry was used to separate and identify Sertoli and germ cell populations in primary rat testicular cultures derived from animals of different ages on the basis of cell size and DNA and lipid content. Multiparameter fluorescent evaluation of each cell preparation resulted in the assignment of specific staining... | 10.1210/endo.130.2.1310280 | 1,310,280 | D029404:Activin Receptors; D028341:Activins; D000375:Aging; D000818:Animals; D002450:Cell Communication; D002469:Cell Separation; D002478:Cells, Cultured; D005434:Flow Cytometry; D007265:Inhibins; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D011956:Receptors, Cell Surface; D018000:Receptors, Peptide; D011... | Endocrinology | 1,992 | D011956:Receptors, Cell Surface; D018000:Receptors, Peptide; D011994:Recombinant Proteins; D028341:Activins; D007265:Inhibins; D029404:Activin Receptors |
Systematic investigation of parameters affecting the performance of an agitated filter-dryer. | A systematic experimental investigation of contact drying operation was carried out in an agitated Charles Thompson filter-dryer. In this study, the effect of process parameters (wall temperature, impeller speed, fill level) on the drying performance in the filter-dryer is quantified as a function of bed temperature an... | 10.1002/jps.23572 | 23,650,096 | D002152:Calorimetry, Differential Scanning; D003890:Desiccation; D004867:Equipment Design; D005374:Filtration; D006358:Hot Temperature; D007785:Lactose; D033362:Powder Diffraction; D014961:X-Ray Diffraction | Journal of pharmaceutical sciences | 2,013 | D007785:Lactose |
Effect of Nucleos(t)ide Analogue Therapy on Risk of Intrahepatic Cholangiocarcinoma in Patients With Chronic Hepatitis B. | BACKGROUND & AIMS
Chronic infection with hepatitis B virus (HBV) increases risk of intrahepatic cholangiocarcinoma (ICC), but it is not clear whether antiviral therapy reduces risk. We investigated the association between nucleos(t)ide analogue therapy and ICC risk.
METHODS
We performed a nationwide long-term cohort ... | 10.1016/j.cgh.2017.09.031 | 28,951,229 | D000328:Adult; D000368:Aged; D000818:Animals; D000998:Antiviral Agents; D018281:Cholangiocarcinoma; D005260:Female; D019698:Hepatitis C, Chronic; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009705:Nucleosides; D009711:Nucleotides; D012189:Retrospective Studies; D018570:Risk Assessment; D01362... | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association | 2,018 | D000998:Antiviral Agents; D009705:Nucleosides; D009711:Nucleotides |
Oncologic safety of the submental flap for reconstruction in oral cavity malignancies. | OBJECTIVES
To evaluate the oncologic safety of the submental flap regarding potential transposition of involved nodes to the reconstruction site and recognize the submental flap as an excellent option for oral cavity reconstruction.
STUDY DESIGN
Case series with chart review.
SETTING
Tertiary academic referral cent... | 10.1177/0194599814520687 | 24,503,306 | D000046:Academic Medical Centers; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes; D008297:Male; ... | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery | 2,014 | |
Non-reproductive systems and the pineal gland. | The paper reviews the data accumulated on the interrelationship between the pineal gland and the central nervous system as evidenced by induced neuroanatomical, biochemical and hormonal changes taking place in one system following the activation or inhibition of the other. The possible role of the pineal in modifying b... | 381,587 | D000311:Adrenal Glands; D000818:Animals; D001522:Behavior, Animal; D001921:Brain; D006801:Humans; D001523:Mental Disorders; D010179:Pancreas; D010280:Parathyroid Glands; D010870:Pineal Gland; D010902:Pituitary Gland; D013950:Thymus Gland; D013961:Thyroid Gland | Journal of neural transmission. Supplementum | 1,978 | ||
Nitric oxide induces Ca2+-independent activity of the Ca2+/calmodulin-dependent protein kinase II (CaMKII). | Both signaling by nitric oxide (NO) and by the Ca(2+)/calmodulin (CaM)-dependent protein kinase II α isoform (CaMKIIα) are implicated in two opposing forms of synaptic plasticity underlying learning and memory, as well as in excitotoxic/ischemic neuronal cell death. For CaMKIIα, these functions specifically involve als... | 10.1074/jbc.M114.558254 | 24,855,644 | D002118:Calcium; D054732:Calcium-Calmodulin-Dependent Protein Kinase Type 2; D016923:Cell Death; D057809:HEK293 Cells; D006801:Humans; D009474:Neurons; D009569:Nitric Oxide; D010766:Phosphorylation; D015290:Second Messenger Systems | The Journal of biological chemistry | 2,014 | D009569:Nitric Oxide; D054732:Calcium-Calmodulin-Dependent Protein Kinase Type 2; D002118:Calcium |
A pilot study of social competence assessment using interaction rating scale advanced. | Purpose. The purpose of this paper is to clarify the validity of the Interaction Rating Scale Advanced (IRSA) as an evidence-based practical index of social skills. Methods. The participants in our study were 17 high school students. The participants completed the five-minute interaction session and were observed using... | 10.5402/2011/272913 | 22,389,772 | ISRN pediatrics | 2,011 | ||
Metabolism of protein and RNA in liver of rats deprived of tryptophan. | Rat lost body weight after the second day of feeding a tryptophan free diet. After 15 days of tryptophan deprivation, they had lost 17% of body weight, whereas pair-fed controls had gained weight. Liver weights of deprived rats were significantly lower than those of controls. Water, protein, RNA, and DNA in the livers ... | 10.1093/jn/107.9.1737 | 894,371 | D000596:Amino Acids; D000818:Animals; D001834:Body Water; D002467:Cell Nucleus; D003593:Cytoplasm; D004247:DNA; D008099:Liver; D008297:Male; D009963:Orotic Acid; D014176:Protein Biosynthesis; D011506:Proteins; D012313:RNA; D051381:Rats; D013997:Time Factors; D014364:Tryptophan | The Journal of nutrition | 1,977 | D000596:Amino Acids; D011506:Proteins; D009963:Orotic Acid; D012313:RNA; D014364:Tryptophan; D004247:DNA |
KDR activation in astrocytic neoplasms. | BACKGROUND
The development of new capillary networks appears to be necessary for the growth of solid tumors. Tumor angiogenesis is believed to be mediated by soluble factors released from tumor cells that then act on endothelial cells in a paracrine manner. Vascular endothelial growth factor (VEGF) is a prime regulator... | 10.1002/(sici)1097-0142(19991001)86:7<1335::aid-cncr32>3.0.co;2-z | 10,506,722 | D000906:Antibodies; D001254:Astrocytoma; D015153:Blotting, Western; D001932:Brain Neoplasms; D002460:Cell Line; D018450:Disease Progression; D016228:Endothelial Growth Factors; D005260:Female; D005909:Glioblastoma; D006801:Humans; D008222:Lymphokines; D008297:Male; D009389:Neovascularization, Pathologic; D010766:Phosph... | Cancer | 1,999 | D000906:Antibodies; D016228:Endothelial Growth Factors; D008222:Lymphokines; D020033:Protein Isoforms; D017978:Receptors, Growth Factor; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors; D020794:Receptor Protein-Tyrosine Kinases; D040262:Receptors, Vascular Endothelial Growth Fa... |
Spectrum of pediatric tumors diagnosed by fine-needle aspiration cytology. | Pediatric tumors differ markedly from adult tumors in their nature, distribution, and prognosis. In this 10-year retrospective study, we present our experience with fine-needle aspiration (FNA) in pediatric patients 18 years of age and younger and correlate relationship between gender with organ, diagnosis, malignancy,... | 10.1097/MD.0000000000005480 | 28,178,123 | D000293:Adolescent; D044963:Biopsy, Fine-Needle; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007492:Iran; D008297:Male; D009369:Neoplasms; D012189:Retrospective Studies | Medicine | 2,017 | |
Polyacrylonitrile complement activation attenuated by simultaneous ultrafiltration and adsorption. | The highly permeable synthetic polyacrylonitrile (PAN) membrane (Filtral; Hospal, Basle) is regarded as biocompatible for its slight complement activation and leucocyte sequestration. The low C3a and C5a concentrations during PAN dialysis may be due to a lack of complement activation potential of this polymer, but also... | 3,118,267 | D000180:Acrylic Resins; D000327:Adsorption; D003167:Complement Activation; D003176:Complement C3; D015926:Complement C3a; D003181:Complement C4; D015934:Complement C4a; D003182:Complement C5; D015936:Complement C5a; D006801:Humans; D007676:Kidney Failure, Chronic; D007688:Kidneys, Artificial; D008567:Membranes, Artific... | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association | 1,987 | D000180:Acrylic Resins; D003176:Complement C3; D003181:Complement C4; D003182:Complement C5; D008567:Membranes, Artificial; C010504:polyacrylonitrile; D015926:Complement C3a; D015934:Complement C4a; D015936:Complement C5a | |
Association between peripheral muscle strength, exercise performance, and physical activity in daily life in patients with Chronic Obstructive Pulmonary Disease. | BACKGROUND
Resistance training of peripheral muscles has been recommended in order to increase muscle strength in patients with Chronic Obstructive Pulmonary Disease (COPD). However, whether peripheral muscle strength is associated with exercise performance (EP) and physical activity in daily life (PADL) in these patie... | 10.1186/2049-6958-9-37 | 25,013,723 | Multidisciplinary respiratory medicine | 2,014 | ||
Triclabendazole Induces Pyroptosis by Activating Caspase-3 to Cleave GSDME in Breast Cancer Cells. | Pyroptosis is a form of programmed cell death, in which gasdermin E (GSDME) plays an important role in cancer cells, which can be induced by activated caspase-3 on apoptotic stimulation. Triclabendazole is a new type of imidazole in fluke resistance and has been approved by the FDA for the treatment of fascioliasis and... | 10.3389/fphar.2021.670081 | 34,305,590 | Frontiers in pharmacology | 2,021 | ||
Growth, spread, and extracellular localization of herpes simplex virus 1 in Vero cells in the presence of an anti-gD plaque inhibiting monoclonal antibody. | Evidence for a direct cell-to-cell virus transfer could be provided by an agent that inhibits plaque formation without interfering with the processes that determine plaque growth in the exit and reinfection pathway of virus transfer. We studied the process of Vero cell infection by herpes simplex virus type 1 laborator... | 9,497,931 | D000818:Animals; D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D002462:Cell Membrane; D002522:Chlorocebus aethiops; D018259:Herpesvirus 1, Human; D008854:Microscopy, Electron; D014709:Vero Cells; D014759:Viral Envelope Proteins; D010948:Viral Plaque Assay; D014771:Virion | The new microbiologica | 1,998 | D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D014759:Viral Envelope Proteins; C039447:glycoprotein D, Human herpesvirus 1 | |
Health for all through research. | John F. Kennedy's vision of man on the moon by the year 1970 set a goal for technological research and development. The World Health Organization's vision of health for all by the year 2000 set a similar goal not only for health policy but also for health research. Drawing on the analogy between these goals, this paper... | 1,854,260 | D014943:Global Health; D006801:Humans; D012106:Research; D014944:World Health Organization | Arhiv za higijenu rada i toksikologiju | 1,991 | ||
Exact integral solution of saturation and depletion in forward and backward optical fiber Raman amplifiers. | Exact integral solutions of forward and backward Raman Stokes-pump interaction are presented. They enable one to determine the gain and depletion characteristics of optical Raman amplifiers, as well as a good approximation of the noise figure, without the need of numerically solving the nonlinear boundary value differe... | 10.1364/ol.32.003023 | 17,938,687 | Optics letters | 2,007 | ||
Prerestorative considerations for cosmetic dentistry. | Helping patients improve their appearance with esthetic procedures can be very rewarding. Optimal esthetic results often require a multidisciplinary approach and sequenced care. Treatment planning with a team approach offers the potential for multiple perspectives and the best opportunity to achieve the optimal results... | 12,216,917 | D000293:Adolescent; D000328:Adult; D016556:Crown Lengthening; D003442:Crowns; D003481:Cuspid; D017266:Dental Prosthesis; D003801:Dental Veneers; D004955:Esthetics, Dental; D005260:Female; D005881:Gingiva; D006801:Humans; D007180:Incisor; D008297:Male; D008437:Maxilla; D003765:Models, Dental; D010348:Patient Care Team; ... | Journal of the California Dental Association | 2,002 | ||
Albumin-bilirubin grade versus MELD score for predicting survival after transjugular intrahepatic portosystemic shunt (TIPS) creation. | OBJECTIVES
The purpose of this study was to compare the albumin-bilirubin (ALBI) grade and model for end-stage liver disease (MELD) scores for predicting survival after transjugular intrahepatic portosystemic shunt (TIPS) creation.
MATERIALS AND METHODS
A retrospective study of pre-procedure ALBI and MELD scores was ... | 10.1016/j.diii.2017.10.008 | 29,154,015 | D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001201:Ascites; D001663:Bilirubin; D005260:Female; D006470:Hemorrhage; D006801:Humans; D006876:Hydrothorax; D008103:Liver Cirrhosis; D008297:Male; D008875:Middle Aged; D019168:Portasystemic Shunt, Transjugular Intrahepatic; D012189:Retrospective Studies; D012709:... | Diagnostic and interventional imaging | 2,018 | D012709:Serum Albumin; D001663:Bilirubin |
[Expansion in breast surgery]. | Skin expansion in breast reconstruction presents several specificities related to mastectomy, retromuscular dissection, and the oncological context. In delayed reconstruction (DR), the local clinical examination is essential to select indications and to eliminate high-risk cases (sequelae of radiotherapy, Halsted, etc.... | 9,687,605 | D001941:Breast Diseases; D018427:Breast Implants; D062109:Dermatologic Surgical Procedures; D005260:Female; D006801:Humans; D016462:Mammaplasty; D015626:Tissue Expansion | Annales de chirurgie plastique et esthetique | 1,996 | ||
Physiologically Based Pharmacokinetic Modeling to Understand the Absorption of Risperidone Orodispersible Film. | OBJECTIVE
The aim of the present study was to investigate the absorption routes as well as the potential application of the oral transmucosal delivery of risperidone orodispersible film (ODF) using physiologically based pharmacokinetic modeling.
METHODS
The pharmacokinetic study after intragastric (i.g.), supralingua... | 10.3389/fphar.2019.01692 | 32,116,683 | Frontiers in pharmacology | 2,019 | ||
A novel ternary heterogeneous TiO2/BiVO4/NaY-Zeolite nanocomposite for photocatalytic degradation of microcystin-leucine arginine (MC-LR) under visible light. | Microcystin-leucine arginine (MC-LR) is a carcinogenic toxin, produced by cyanobacteria. The release of this toxin into drinking water sources can threaten public health and environmental safety. Therefore, effective MC-LR removal from water resources is necessary. In the present study, the hydrothermal method was used... | 10.1016/j.ecoenv.2020.111862 | 33,429,321 | D001729:Bismuth; D002384:Catalysis; D008027:Light; D008387:Marine Toxins; D052998:Microcystins; D053761:Nanocomposites; D055668:Photochemical Processes; D014025:Titanium; D014638:Vanadates; D014874:Water Pollutants, Chemical; D018508:Water Purification; D015019:Yttrium; D017641:Zeolites | Ecotoxicology and environmental safety | 2,021 | D008387:Marine Toxins; D052998:Microcystins; D014874:Water Pollutants, Chemical; D017641:Zeolites; C091754:bismuth vanadium tetraoxide; C009495:titanium dioxide; D014638:Vanadates; D015019:Yttrium; D014025:Titanium; C057862:cyanoginosin LR; D001729:Bismuth |
The effect of weak π-π interactions on single-molecule electron transport properties of the tetraphenylethene molecule and its derivatives: a first-principles study. | Intramolecular π-π interactions are a significant research focus in fields such as chemistry, biology, and materials science. Different configurations of benzene-benzene moieties within a molecule can affect the magnitude of their π-π interactions, consequently influencing the electronic transport capabilities of the m... | 10.1039/d3cp04593e | 38,095,244 | Physical chemistry chemical physics : PCCP | 2,023 | ||
Minimum Clinically Important Difference in Patients Undergoing Minimally Invasive Transforaminal Lumbar Interbody Fusion. | BACKGROUND
Few studies have established the minimum clinically important difference (MCID) in patients undergoing minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) for physical function and pain.
OBJECTIVE
To establish MCID for physical function and pain patient-reported outcome measures (PROMs) fo... | 10.1227/neu.0000000000002350 | 36,625,578 | D006801:Humans; D008159:Lumbar Vertebrae; D016896:Treatment Outcome; D003430:Cross-Sectional Studies; D013123:Spinal Fusion; D019060:Minimally Invasive Surgical Procedures; D010146:Pain | Neurosurgery | 2,023 | |
Familial synchronous bilateral teratoid Wilms tumor with elevated alpha-fetoprotein level. | Familial Wilms tumor is a rare entity that accounts for only 1-2% of all Wilms tumor cases, with an earlier age of onset and an increased frequency of bilateral tumors. Teratoid Wilms tumor is a variant of nephroblastoma with a predominance of heterologous tissues comprising more than 50% of the tumor volume. Wilms tum... | 10.1700/1217.13518 | 23,389,381 | D014408:Biomarkers, Tumor; D003645:Death, Sudden; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms; D008297:Male; D008487:Medical History Taking; D042965:Methylenetetrahydrofolate Reductase (NADPH2); D009154:Mutation; D018365:Neoplasm, Residual; D009378:Neoplasms, Multiple Primary; D009392:Nephrectomy; D010530:... | Tumori | 2,012 | D014408:Biomarkers, Tumor; D000509:alpha-Fetoproteins; C573423:MTHFR protein, human; D042965:Methylenetetrahydrofolate Reductase (NADPH2) |
Catecholaminergic innervation of guinea pig superior olivary complex. | In mammals, olivocochlear neurons in the superior olivary complex project to the cochlea, providing input to outer hair cells and auditory afferents contacting inner hair cells. In the rat it has been demonstrated that olivocochlear neurons receive noradrenergic input, arising from the locus coeruleus and it has been d... | 10.1016/j.jchemneu.2005.09.005 | 16,236,480 | D000818:Animals; D001306:Auditory Pathways; D003051:Cochlea; D004298:Dopamine; D004299:Dopamine beta-Hydroxylase; D005260:Female; D006168:Guinea Pigs; D007150:Immunohistochemistry; D008125:Locus Coeruleus; D008297:Male; D009434:Neural Pathways; D009847:Olivary Nucleus; D014446:Tyrosine 3-Monooxygenase | Journal of chemical neuroanatomy | 2,005 | D014446:Tyrosine 3-Monooxygenase; D004299:Dopamine beta-Hydroxylase; D004298:Dopamine |
Effect of Rose Syrup and Marigold Powder on the Physicochemical, Phytochemical, Sensorial and Storage Properties of Nutricereals and Milk-Based Functional Beverage. | ABSTACTAim: The present study aimed to investigate the effect of rose sirup and marigold powder on the physicochemical properties, bioactive potential, sensory acceptability and storage life of the nutricereals (finger millet, oats) and milk-based functional beverage (FB).Method: Preliminary trials were performed using... | 10.1080/07315724.2020.1744487 | 32,207,660 | D000818:Animals; D000872:Anthocyanins; D001628:Beverages; D006801:Humans; D008892:Milk; D064209:Phytochemicals; D011208:Powders; D027826:Rosa | Journal of the American College of Nutrition | 2,021 | D000872:Anthocyanins; D064209:Phytochemicals; D011208:Powders |
Secretion of EGF-like domain of heregulinβ promotes axonal growth and functional recovery of injured sciatic nerve. | Neuregulin 1 (NRG1) and epidermal growth factor receptor (ErbB) signaling pathways control Schwann cells during axonal regeneration in an injured peripheral nervous system. We investigated whether a persistent supply of recombinant NRG1 to the injury site could improve axonal growth and recovery of sensory and motor fu... | 10.1007/s10059-010-0137-5 | 20,957,456 | D000256:Adenoviridae; D000818:Animals; D001369:Axons; D019771:Axotomy; D002460:Cell Line; D004274:DNA, Recombinant; D004815:Epidermal Growth Factor; D019922:GAP-43 Protein; D006801:Humans; D008297:Male; D009416:Nerve Regeneration; D020890:Neuregulin-1; D010766:Phosphorylation; D051381:Rats; D017207:Rats, Sprague-Dawley... | Molecules and cells | 2,010 | D004274:DNA, Recombinant; D019922:GAP-43 Protein; D020890:Neuregulin-1; C490580:Nrg1 protein, rat; D011994:Recombinant Proteins; D009418:S100 Proteins; D004815:Epidermal Growth Factor; D020893:Receptor, ErbB-3 |
[Clinical symptoms of mitral valve prolapse. Treatment with metoprolol (author's transl)]. | Twelve patients with symptomatic mitral valve prolapse were given metoprolol. The efficacy of the drug was evaluated on clinical improvement and changes in echocardiograms, exercise testing and 24 h ambulatory electrocardiograms. The efficacy of metoprolol was remarkable on palpitations and cardiac arrhythmias recorded... | 6,278,609 | D000293:Adolescent; D000328:Adult; D000368:Aged; D004452:Echocardiography; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008790:Metoprolol; D008875:Middle Aged; D008945:Mitral Valve Prolapse; D011412:Propanolamines | La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris | 1,982 | D011412:Propanolamines; D008790:Metoprolol | |
Ultrasonically enhanced extraction of luteolin and apigenin from the leaves of Perilla frutescens (L.) Britt. using liquid carbon dioxide and ethanol. | The present study reports on the ultrasonic enhancement of the liquid carbon dioxide (CO2) extraction of luteolin and apigenin from the leaves of Perilla frutescens (L.) Britt., to which ethanol is added as a cosolvent. The purpose of this research is also to investigate the effects of the particle size, temperature, p... | 26,584,980 | D047310:Apigenin; D002245:Carbon Dioxide; D005591:Chemical Fractionation; D000431:Ethanol; D047311:Luteolin; D031344:Perilla frutescens; D018515:Plant Leaves; D011312:Pressure; D012997:Solvents; D013696:Temperature; D013997:Time Factors; D000069453:Ultrasonic Waves | Ultrasonics sonochemistry | 2,016 | D012997:Solvents; D002245:Carbon Dioxide; D000431:Ethanol; D047310:Apigenin; D047311:Luteolin | |
Validation of the OECD reproduction test guideline with the New Zealand mudsnail Potamopyrgus antipodarum using trenbolone and prochloraz. | The Organisation for Economic Cooperation and Development (OECD) provides several standard test methods for the environmental hazard assessment of chemicals, mainly based on primary producers, arthropods, and fish. In April 2016, two new test guidelines with two mollusc species representing different reproductive strat... | 10.1007/s10646-017-1770-y | 28,168,557 | D045930:Anabolic Agents; D000818:Animals; D052244:Endocrine Disruptors; D004784:Environmental Monitoring; D005260:Female; D005659:Fungicides, Industrial; D017408:Guidelines as Topic; D007093:Imidazoles; D009520:New Zealand; D066150:Organisation for Economic Co-Operation and Development; D015203:Reproducibility of Resul... | Ecotoxicology (London, England) | 2,017 | D045930:Anabolic Agents; D052244:Endocrine Disruptors; D005659:Fungicides, Industrial; D007093:Imidazoles; D014874:Water Pollutants, Chemical; C045362:prochloraz; D014204:Trenbolone Acetate |
What contributions do languages other than English make on the results of meta-analyses? | Including only a portion of all available evidence may introduce systematic errors into the meta-analytic process and threaten its validity. We set out to examine whether language restricted meta-analyses, compared to language inclusive meta-analyses, provide different estimates of the effectiveness of interventions ev... | 10.1016/s0895-4356(00)00188-8 | 11,004,423 | D006801:Humans; D007802:Language; D016015:Logistic Models; D015201:Meta-Analysis as Topic; D017063:Outcome Assessment, Health Care; D016032:Randomized Controlled Trials as Topic; D015983:Selection Bias | Journal of clinical epidemiology | 2,000 | |
The ageing ovary and uterus: new biological insights. | BACKGROUND Advanced maternal age is associated with reduced fertility and adverse pregnancy outcomes. This review details recent developments in our understanding of the biology and mechanisms underlying reproductive ageing in women and the implications for fertility and pregnancy. METHODS Sociological online librarie... | 10.1093/humupd/dms043 | 23,103,636 | D000375:Aging; D005260:Female; D005298:Fertility; D005333:Fetus; D005854:Germ Cells; D006801:Humans; D008423:Maternal Age; D009865:Oocytes; D006080:Ovarian Follicle; D010053:Ovary; D011247:Pregnancy; D011256:Pregnancy Outcome; D014599:Uterus | Human reproduction update | 2,013 | |
Safety of argon plasma coagulation for hemostasis during endoscopic mucosal resection. | Showing the safety of argon plasma coagulation (APC) over mucosal defects during/after endoscopic mucosal resection (EMR), 2 studies using resected pig (ex vivo) and living minipig (in vivo) stomachs were performed. As an ex vivo study, APC was applied over mucosal defects in 2 groups; with prior submucosal saline inje... | 10.1097/00129689-200606000-00003 | 16,804,454 | D000818:Animals; D001128:Argon; D016063:Blood Loss, Surgical; D004564:Electrocoagulation; D016099:Endoscopy, Gastrointestinal; D005753:Gastric Mucosa; D016558:Hemostasis, Endoscopic; D013552:Swine; D013556:Swine, Miniature | Surgical laparoscopy, endoscopy & percutaneous techniques | 2,006 | D001128:Argon |
Flow cytometric quantification and characterization of intracellular protein aggregates in yeast. | The sequestration of misfolded proteins into aggregates is an integral pathway of the protein quality control network that becomes particularly prominent during proteotoxic stress and in various pathologies. Methods for systematic analysis of cellular aggregate content are still largely limited to fluorescence microsco... | 10.4161/19336896.2014.968445 | 25,482,598 | D005434:Flow Cytometry; D005656:Fungal Proteins; D049452:Green Fluorescent Proteins; D006360:Heat-Shock Proteins; D066329:Protein Aggregates; D012441:Saccharomyces cerevisiae | Prion | 2,014 | D005656:Fungal Proteins; D006360:Heat-Shock Proteins; D066329:Protein Aggregates; D049452:Green Fluorescent Proteins |
CCAAT/enhancer binding protein (C/EBP) delta promotes the expression of PTX3 and macrophage phagocytosis during A. fumigatus infection. | Given the increasing incidence of pulmonary aspergillosis, it is important to understand the natural defense mechanisms by which the body can kill Aspergillus fumigatus conidia. Pentraxin 3 (PTX3) plays a nonredundant role in resistance to A. fumigatus. Here, we found that the key predicted PTX3 transcription factor, C... | 10.1002/JLB.4MA1121-451RR | 34,939,225 | D001228:Aspergillosis; D001232:Aspergillus fumigatus; D002097:C-Reactive Protein; D051743:CCAAT-Enhancer-Binding Protein-delta; D006801:Humans; D008264:Macrophages; D010587:Phagocytosis; D000683:Serum Amyloid P-Component | Journal of leukocyte biology | 2,022 | C497252:CEBPD protein, human; D000683:Serum Amyloid P-Component; D051743:CCAAT-Enhancer-Binding Protein-delta; C077657:PTX3 protein; D002097:C-Reactive Protein |
Drug misuse in pregnancy: losing sight of the baby? | Maternal drug misuse can seriously affect the health of the fetus and newborn infant. The association of maternal drug misuse with prematurity, intrauterine growth restriction (IUGR) and neonatal abstinence syndrome (NAS) is well recognised, and there is growing concern about infant visual development and longer-term n... | 10.1136/adc.2008.156851 | 19,329,443 | D000328:Adult; D002657:Child Development; D055030:Drug Users; D004569:Electroencephalography; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009035:Mothers; D055495:Neurogenesis; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D014785:Vision, Ocular; D055815:Y... | Archives of disease in childhood | 2,009 | |
Adverse Childhood Experiences and Dental Care Utilization During Pregnancy: Findings from the North and South Dakota PRAMS, 2017-2021. | Background
Research demonstrates adverse childhood experiences (ACEs)-i.e., experiences of abuse, neglect, and household dysfunction-adversely impact healthcare utilization over the life course. Several studies demonstrate that ACEs are related to lower dental care utilization in childhood and adolescence. However, lim... | 10.21203/rs.3.rs-3452502/v1 | 37,886,560 | Research square | 2,023 | ||
Cryptosporidiosis of the biliary tract mimicking pancreatic cancer in an AIDS patient. | Diarrhea caused by Cryptosporidium sp is frequent in patients with AIDS, but involvement of other organs of the digestive tract is uncommon. We report a case of Cryptosporidium-associated obstruction of the biliary tract mimicking cancer of the head of the pancreas in a 43-year-old woman with AIDS. | 10.1590/s0037-86822004000200015 | 15,094,908 | D017088:AIDS-Related Opportunistic Infections; D000328:Adult; D000818:Animals; D002779:Cholestasis; D003457:Cryptosporidiosis; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D010190:Pancreatic Neoplasms | Revista da Sociedade Brasileira de Medicina Tropical | 2,004 | |
Molecular Oxygen Network as a Template for Adsorption of Ammonia on Pt(111). | Low-temperature scanning tunneling microscopy (STM) was used to observe a mixed NH3-O2 overlayer on Pt(111). At adsorption temperatures below 50 K, the chemisorbed O2 molecules form an ordered network at high coverages. The STM images reveal that this network features a distributed set of holes corresponding to on-top ... | 10.1021/jz4015234 | 26,705,578 | The journal of physical chemistry letters | 2,013 | ||
Scintigraphy for evaluation of patients for GI motility disorders--the referring physician's perspective. | Gastrointestinal (GI) motility disorders are common and cause either delayed or accelerated transit through the stomach, small intestine, or colon. Assessment of GI transit times can provide direct measurements and diagnostic information to help explain the cause of symptoms and help plan therapy. Several diagnostic te... | 10.1053/j.semnuclmed.2011.10.006 | 22,293,162 | D003106:Colon; D005746:Gastric Emptying; D005767:Gastrointestinal Diseases; D005769:Gastrointestinal Motility; D005772:Gastrointestinal Transit; D006801:Humans; D010820:Physicians; D011877:Radionuclide Imaging; D012017:Referral and Consultation | Seminars in nuclear medicine | 2,012 | |
A BSL-4 high-throughput screen identifies sulfonamide inhibitors of Nipah virus. | Nipah virus is a biosafety level 4 (BSL-4) pathogen that causes severe respiratory illness and encephalitis in humans. To identify novel small molecules that target Nipah virus replication as potential therapeutics, Southern Research Institute and Galveston National Laboratory jointly developed an automated high-throug... | 10.1089/adt.2013.567 | 24,735,442 | D000818:Animals; D000998:Antiviral Agents; D002522:Chlorocebus aethiops; D003264:Containment of Biohazards; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004867:Equipment Design; D019544:Equipment Failure Analysis; D057166:High-Throughput Screening Assays; D045405:Nipah Virus; D012371... | Assay and drug development technologies | 2,014 | D000998:Antiviral Agents; D013449:Sulfonamides |
Determining the factors causing delayed referral for fetal echocardiography at a tertiary care hospital. | OBJECTIVE
To determine the factors causing delayed referral for fetal echocardiography at a tertiary care hospital.
BACKGROUND
Timely referral for fetal echocardiogram is considered essential for identification of congenital heart diseases, interventions, and counseling of parents. The present study highlights the fa... | 10.1016/j.jsha.2017.12.001 | 29,983,496 | Journal of the Saudi Heart Association | 2,018 | ||
Immigration policy and internationally educated nurses in the United States: A brief history. | Since the 1980s, U.S. policy makers have used immigration policy to influence the supply of nurses by allowing or restricting the entry of internationally educated nurses (IENs) into the U.S. workforce. The methods pursued have shifted over time from temporary visa categories in the 1980s and 1990s to permanent immigra... | 24,345,614 | D004641:Emigration and Immigration; D049673:History, 20th Century; D049674:History, 21st Century; D064700:Nurses, International; D009729:Nursing; D014481:United States; D000078329:Workforce | Nursing outlook | 2,014 | ||
In vivo prediction of carcass composition and muscularity in purebred Texel lambs. | A subjective assessment of the shape of the hind limb of purebred Texel lambs was evaluated as an in vivo predictor of carcass composition and muscularity. Lambs were taken from two flocks that were managed in a common environment, but which had either been selected for lean tissue growth rate or for improved conformat... | 10.1016/j.meatsci.2006.02.019 | 22,062,854 | Meat science | 2,006 | ||
Positivity of Demodex spp. in biopsy specimens of nevi. | Melanocytic skin tumors are caused by nevus cells, epidermal melanocytes and dermal melanocytes. The aim of the study was to detect the positivity of Demodex spp. in biopsy specimens of skin diagnosed as nevus. In this retrospective study, the specimens obtained from 110 patients diagnosed with nevus and stained by hem... | 19,696,727 | D000053:Acari; D000818:Animals; D001706:Biopsy; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008544:Melanocytes; D008924:Mite Infestations; D009506:Nevus; D012189:Retrospective Studies; D012867:Skin; D012878:Skin Neoplasms | Tropical biomedicine | 2,009 | ||
A Novel Orthotopic Mouse Model of Lung Metastasis Using Fluorescent Patient-derived Osteosarcoma Cells. | BACKGROUND
A mouse model of metastatic osteosarcoma is imperative to identify effective agents for metastatic osteosarcoma, which is a recalcitrant disease. In the present study, we established osteosarcoma patient-derived cells (OS-PDCs) and transfected them with green fluorescent protein (GFP).
MATERIALS AND METHOD... | 10.21873/anticanres.14814 | 33,517,267 | D000293:Adolescent; D000818:Animals; D001859:Bone Neoplasms; D058948:Cell Tracking; D005260:Female; D049452:Green Fluorescent Proteins; D006801:Humans; D008175:Lung Neoplasms; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D012516:Osteosarcoma; D013977:Tibia; D014162:Transfection; D014407:Tumor Cells, Cultured | Anticancer research | 2,021 | D049452:Green Fluorescent Proteins |
PAciFy Cough-a multicentre, double-blind, placebo-controlled, crossover trial of morphine sulphate for the treatment of pulmonary Fibrosis Cough. | BACKGROUND
Idiopathic pulmonary fibrosis (IPF) is a progressive disease that leads to lung scarring. Cough is reported by 85% of patients with IPF and can be a distressing symptom with a significant impact on patients' quality of life. There are no proven effective therapies for IPF-related cough. Whilst morphine is fr... | 10.1186/s13063-022-06068-4 | 35,236,391 | D003371:Cough; D018592:Cross-Over Studies; D004311:Double-Blind Method; D006801:Humans; D054990:Idiopathic Pulmonary Fibrosis; D009020:Morphine; D011788:Quality of Life; D016896:Treatment Outcome | Trials | 2,022 | D009020:Morphine |
CMV-associated collapsing focal segmental glomerulosclerosis after kidney transplant in a pediatric patient. | BACKGROUND
Cytomegalovirus (CMV) is a significant cause of morbidity among immunocompromised patients who have undergone kidney transplantation and is known to rarely induce collapsing focal segmental glomerulosclerosis (FSGS) among adults.
METHODS
We present the first reported case of CMV-induced collapsing FSGS in ... | 10.1111/petr.14535 | 37,128,132 | D008297:Male; D000328:Adult; D006801:Humans; D002648:Child; D005923:Glomerulosclerosis, Focal Segmental; D016030:Kidney Transplantation; D003587:Cytomegalovirus; D007676:Kidney Failure, Chronic; D003586:Cytomegalovirus Infections; D000075944:Apolipoprotein L1 | Pediatric transplantation | 2,023 | C108666:APOL1 protein, human; D000075944:Apolipoprotein L1 |
Prolonged Plasmodium falciparum infection in immigrants, Paris. | Few immigrant travelers have Plasmodium falciparum infections >2 months after leaving malaria-endemic areas. We conducted a case-control study to identify factors associated with prolonged P. falciparum infection in immigrant travelers. Results suggest that P. falciparum infection should be systematically suspected, ev... | 10.3201/eid1402.061475 | 18,258,132 | D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000962:Antimalarials; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004641:Emigration and Immigration; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D016015:Logistic Models; D016778:Malaria, Falciparum; D00... | Emerging infectious diseases | 2,008 | D000962:Antimalarials; D015767:Mefloquine |
Clinical Study of Styping Detection of Human Papillomavirus (HPV) Infection with Microarray from Paraffinembedded Specimens of Cervical Cancer and Precursor Lesions. | The prevalence and type distribution of human papillomavirus (HPV) in cervical cancer and cervical intraepithelial neoplasia (CIN) in Jiangsu, China was investigated. A total of 93 cases with cervical cancer and 176 CINII-III tissue samples were obtained from women undergoing biopsy or surgery. The 1047 exfoliated cerv... | 10.1166/jnn.2015.10336 | 26,716,195 | D000328:Adult; D004279:DNA, Viral; D005260:Female; D006801:Humans; D008875:Middle Aged; D020411:Oligonucleotide Array Sequence Analysis; D027383:Papillomaviridae; D030361:Papillomavirus Infections; D016612:Paraffin Embedding; D002583:Uterine Cervical Neoplasms; D055815:Young Adult; D002578:Uterine Cervical Dysplasia | Journal of nanoscience and nanotechnology | 2,015 | D004279:DNA, Viral |
Factors affecting the fermentative production of a lysozyme-binding antibody fragment in Escherichia coli. | Fed-batch fermentation for production of a single-chain Fv antibody fragment (scFv) expressed as a recombinant periplastic protein from Escherichia coli was investigated. A high cell density of 50 g dry cell weight per liter was routinely achieved in a 14-L vessel by controlled exponential feeding of glucose to impose ... | 10.1002/(SICI)1097-0290(19970320)53:6<611::AID-BIT9>3.0.CO;2-P | 18,634,062 | Biotechnology and bioengineering | 1,997 | ||
Purification and characterization of anticoagulant protein from the tabanus, Tabanus bivittatus. | Tabanus anticoagulant protein (TAP) was isolated from the whole body of the tabanus, Tabanus bivittatus, using three purification steps (ammonium sulfate fractionation, gel filtration on Bio-Gel P-60, and ion exchange chromatography on DEAE Sephadex gel). The purified TAP, with a molecular weight of 65 kDa, was assesse... | 10.1007/BF02968593 | 16,756,088 | D000818:Animals; D000925:Anticoagulants; D001777:Blood Coagulation; D002413:Cations, Divalent; D002863:Chromogenic Compounds; D003300:Copper; D004175:Diptera; D006863:Hydrogen-Ion Concentration; D019476:Insect Proteins; D008970:Molecular Weight; D010314:Partial Thromboplastin Time; D011487:Protein Conformation; D013696... | Archives of pharmacal research | 2,006 | D000925:Anticoagulants; D002413:Cations, Divalent; D002863:Chromogenic Compounds; D019476:Insect Proteins; D003300:Copper; D013917:Thrombin; D015032:Zinc |
The role of familiarity on modeling of eating and food consumption in children. | This study investigates the effects of peer and sibling influence on the cookie intake of normal-weight children. A total of 44 children (24 girls and 20 boys) aged 5-11 participated in this study. Children played a sorting task while being exposed to a large amount of cookies. Children were tested alone or with an unf... | 10.1016/j.appet.2007.10.009 | 18,068,854 | D002648:Child; D002664:Child Nutritional Physiological Phenomena; D002675:Child, Preschool; D004435:Eating; D002149:Energy Intake; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D010379:Peer Group; D035781:Siblings; D012919:Social Behavior; D012932:Social Facili... | Appetite | 2,008 | |
Comparison of various blood compartments and reporting units for the detection and quantification of Epstein-Barr virus in peripheral blood. | Epstein-Barr virus (EBV) infection is associated with a broad spectrum of disease. While quantification of EBV nucleic acid in the peripheral blood has been demonstrated to be useful for diagnosis and patient care, the optimal sample type and reporting format for such testing remain uncertain. Using quantitative real-t... | 10.1128/JCM.02308-06 | 17,494,720 | D004279:DNA, Viral; D020031:Epstein-Barr Virus Infections; D004912:Erythrocytes; D004854:Herpesvirus 4, Human; D006801:Humans; D007963:Leukocytes, Mononuclear; D010949:Plasma; D012680:Sensitivity and Specificity; D019562:Viral Load | Journal of clinical microbiology | 2,007 | D004279:DNA, Viral |
Synthesis: comparing effects of resource and consumer fluxes into recipient food webs using meta-analysis. | Here we synthesize empirical research using meta-analysis to compare how consumer and resource fluxes affect recipient food webs. We tested the following hypotheses: (H1) The direct effects of resource fluxes (bottom-up) should be stronger than the direct effects of consumer fluxes (top-down), because resource fluxes a... | 27,197,387 | D000818:Animals; D020387:Food Chain; D008954:Models, Biological | Ecology | 2,016 | ||
Intraventricular hemorrhage expansion in patients with spontaneous intracerebral hemorrhage. | OBJECTIVE
To evaluate whether delayed appearance of intraventricular hemorrhage (dIVH) represents an independent entity from intraventricular hemorrhage (IVH) present on admission CT or is primarily related to the time interval between symptom onset and admission CT.
METHODS
A total of 282 spontaneous intracerebral h... | 10.1212/WNL.0000000000001344 | 25,663,233 | D000368:Aged; D000369:Aged, 80 and over; D002543:Cerebral Hemorrhage; D002552:Cerebral Ventricles; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006406:Hematoma; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D013997:Time Factors; D016896:Treatment Outcome | Neurology | 2,015 | |
Pr3+-doped heavy metal germanium tellurite glasses for irradiative light source in minimally invasive photodynamic therapy surgery. | Pr3+-doped medium-low phonon energy heavy metal germanium tellurite (NZPGT) glasses have been fabricated and the intense multi-peak red fluorescence emissions of Pr3+ are exhibited. Judd-Ofelt parameters Ω2 = 3.14 × 10(-20)cm(2), Ω4 = 10.67 × 10(-20)cm(2) and Ω6 = 3.95 × 10(-20)cm(2) indicate a high asymmetrical and co... | 10.1364/OE.21.001030 | 23,388,997 | Optics express | 2,013 | ||
Post-Treatment Neck Dissection of Tonsillar and Base of Tongue Squamous Cell Carcinoma in the Era of PET-CT, HPV, and p16. | Human-papillomavirus (HPV)-positive tonsillar and base of tongue carcinomas (TSCC/BOTSCC) are rising in incidence and treatments with radiotherapy, chemoradiotherapy (RT/CRT), and neck dissections (NDs) have several side effects. Therefore, an improved selection of patients needing salvage NDs would be beneficial. We e... | 10.3390/v14081693 | 36,016,315 | D002294:Carcinoma, Squamous Cell; D019788:Fluorodeoxyglucose F18; D006258:Head and Neck Neoplasms; D006801:Humans; D037981:Neck Dissection; D027383:Papillomaviridae; D030361:Papillomavirus Infections; D000072078:Positron Emission Tomography Computed Tomography; D012189:Retrospective Studies; D014059:Tongue; D014062:Ton... | Viruses | 2,022 | D019788:Fluorodeoxyglucose F18 |
Analysis of 3-D microstructure of porous poly(lactide-glycolide) matrices using confocal microscopy. | Porous matrices of biodegradable polymers are extensively used as scaffolds in tissue engineering and as drug delivery devices. A critical component of the design, processing, and utility of such polymeric systems concerns the local void microarchitecture. In this study, a novel approach based on confocal fluorescence ... | 10.1002/(sici)1097-4636(199823)43:3<291::aid-jbm10>3.0.co;2-j | 9,730,067 | D001672:Biocompatible Materials; D019344:Lactic Acid; D018613:Microscopy, Confocal; D015394:Molecular Structure; D011100:Polyglycolic Acid; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011108:Polymers | Journal of biomedical materials research | 1,998 | D001672:Biocompatible Materials; D011108:Polymers; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid |
The heterohexameric complex structure, a component in the non-classical pathway for fibroblast growth factor 1 (FGF1) secretion. | Fibroblast growth factors (FGFs) are key regulators of cell proliferation, tumor-induced angiogenesis, and migration. FGFs are essential for early embryonic development, organ formation, and angiogenesis. FGF1 also plays an important role in inflammation, wound healing, and restenosis. The biological effects of FGF1 ar... | 10.1074/jbc.M109.066357 | 20,220,137 | D002151:Calorimetry; D016220:Fibroblast Growth Factor 1; D006801:Humans; D008958:Models, Molecular; D019906:Nuclear Magnetic Resonance, Biomolecular; D011487:Protein Conformation | The Journal of biological chemistry | 2,010 | D016220:Fibroblast Growth Factor 1 |
A Novel Enhancement Approach Following MVMD and NMF Separation of Complex Snoring Signals. | Snoring is a prominent characteristic of sleep-disordered breathing, and its detection is critical for determining the severity of the upper airway obstruction and improving daily quality of life. Home snoring analysis is a highly invasive method, but it becomes challenging when a sleeping partner also snores, leading ... | 10.1109/TBME.2023.3308296 | 37,616,136 | IEEE transactions on bio-medical engineering | 2,023 | ||
Arsenic, Cadmium, Lead, and Mercury in Lactation Foods and Prenatal Vitamins: Potentially Avoidable Exposure for Breastfeeding Mothers and Infants. | Human milk is a biofluid that can contain heavy metals such as arsenic, cadmium, lead, and mercury. These toxins can adversely affect endocrine, respiratory, immune, and nervous systems. Infants may have higher dietary arsenic exposure than adults due to their more restricted diets and greater intake per unit body mass... | 10.1089/bfm.2020.0359 | 33,567,220 | D000328:Adult; D001151:Arsenic; D001942:Breast Feeding; D002104:Cadmium; D005260:Female; D006801:Humans; D007223:Infant; D007774:Lactation; D008628:Mercury; D009035:Mothers; D014815:Vitamins | Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine | 2,021 | D014815:Vitamins; D002104:Cadmium; D008628:Mercury; D001151:Arsenic |
Effects of malnutrition and chronic reserpine treatment on pancreatic exocrine function. | The chronically reserpine-treated rat, an experimental model for cystic fibrosis, exhibits generalized exocrinopathy, impaired pancreatic secretion, and decreased pancreatic amylase. Although chronic reserpine treatment induces malnutrition by decreasing food consumption and growth, the effects of this malnutrition per... | 10.1203/00006450-198612000-00009 | 2,432,455 | D000681:Amylases; D000818:Animals; D001835:Body Weight; D003550:Cystic Fibrosis; D004195:Disease Models, Animal; D004435:Eating; D008049:Lipase; D008297:Male; D009748:Nutrition Disorders; D009929:Organ Size; D010179:Pancreas; D051381:Rats; D011919:Rats, Inbred Strains; D012110:Reserpine; D012844:Sincalide | Pediatric research | 1,986 | D012110:Reserpine; D008049:Lipase; D000681:Amylases; D012844:Sincalide |
Effect of chronic training on heart rate variability, salivary IgA and salivary alpha-amylase in elite swimmers with a disability. | The purpose of this study was to a) determine the heart rate variability (HRV) and saliva markers of immunity (salivary immunoglobulin A; sIgA) and stress (salivary alpha-amylase; sAA) responses to chronic training in elite swimmers with a disability; and b) identify the relationships between HRV, sIgA, sAA and trainin... | 10.1371/journal.pone.0127749 | 26,043,224 | D000293:Adolescent; D000328:Adult; D056352:Athletes; D006233:Disabled Persons; D005260:Female; D006339:Heart Rate; D006801:Humans; D007070:Immunoglobulin A; D008297:Male; D008991:Monitoring, Physiologic; D012463:Saliva; D055291:Salivary alpha-Amylases; D013550:Swimming; D055815:Young Adult | PloS one | 2,015 | D007070:Immunoglobulin A; D055291:Salivary alpha-Amylases |
[Prevalence of hantavirus infections in Germany]. | Hantaviruses belong to the group of "emerging" viruses. Pathogenic European hantaviruses can cause a human disease designated "hemorrhagic fever with renal syndrome" of varying severity. In general, diagnostics of hantavirus infections are based on immunofluorescence assays using virus-infected cells or enzyme immunoas... | 10.1007/s00103-004-0858-8 | 15,254,821 | D003140:Communicable Disease Control; D021821:Communicable Diseases, Emerging; D004196:Disease Outbreaks; D005858:Germany; D018778:Hantavirus Infections; D006801:Humans; D015995:Prevalence; D018570:Risk Assessment; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D012698:Serologic Tests | Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz | 2,004 | |
Long-term phase reorganization of conditioned food aversion memory in edible snail. | The specific features of memory reconsolidation in edible snails were studied over 30 days after learning of conditioned food aversion. Injections of a NMDA glutamate receptor antagonist MK-801 or protein synthesis inhibitor cycloheximide in combination with the conditioned food stimulus (reminder) on day 2 after learn... | 10.1007/s10517-014-2580-3 | 25,110,074 | D000647:Amnesia; D000818:Animals; D003214:Conditioning, Classical; D003513:Cycloheximide; D016291:Dizocilpine Maleate; D018691:Excitatory Amino Acid Antagonists; D005247:Feeding Behavior; D005502:Food; D006372:Helix, Snails; D007858:Learning; D057567:Memory, Long-Term; D011500:Protein Synthesis Inhibitors; D016194:Rece... | Bulletin of experimental biology and medicine | 2,014 | D018691:Excitatory Amino Acid Antagonists; D011500:Protein Synthesis Inhibitors; D016194:Receptors, N-Methyl-D-Aspartate; D016291:Dizocilpine Maleate; D003513:Cycloheximide |
Low levels of classical BSE infectivity in rendered fat tissue. | BSE infectivity in mesentery fat is most likely associated with embedded nervous tissue. To prove this mesentery containing celiac ganglion was taken from oral BSE infected cattle in different stages of the disease and from one control animal. Fat was rendered according to standard tallow production methods and the pri... | 10.1186/s13567-018-0618-7 | 30,572,960 | D050153:Abdominal Fat; D000818:Animals; D002417:Cattle; D016643:Encephalopathy, Bovine Spongiform; D005728:Ganglia, Sympathetic; D008643:Mesentery; D051379:Mice; D008822:Mice, Transgenic | Veterinary research | 2,018 | |
Carbonic anhydrase inhibition and calcium transients in soleus fibers. | We simultaneously measured cytoplasmic Ca2+ transients using Fura-2 and isometric force in rat soleus fiber bundles. In the presence of the carbonic anhydrase inhibitor, chlorzolamide, we observed a decreased amplitude and retarded decay of the Ca2+ signal. This corresponded with a decreased isometric force and a retar... | 10.1016/0014-5793(90)80289-u | 2,114,323 | D000086:Acetazolamide; D000138:Acidosis; D000818:Animals; D001692:Biological Transport; D002118:Calcium; D002257:Carbonic Anhydrase Inhibitors; D002256:Carbonic Anhydrases; D005260:Female; D007527:Isoenzymes; D007700:Kinetics; D009119:Muscle Contraction; D009132:Muscles; D051381:Rats; D011919:Rats, Inbred Strains; D012... | FEBS letters | 1,990 | D002257:Carbonic Anhydrase Inhibitors; D007527:Isoenzymes; D012097:Repressor Proteins; D013830:Thiadiazoles; D014157:Transcription Factors; C000471:chlorzolamide; D002256:Carbonic Anhydrases; D000086:Acetazolamide; D002118:Calcium |
Interleukin-1 bioactivity and DNA synthesis in X-irradiated rat testes. | Stage-specific DNA synthesis and interleukin-1 (IL-1) bioactivity were measured in the rat testis at 2, 6, 12 and 25 days after local irradiation with 3 Gy to investigate whether there was any correlation between germ cell DNA synthesis during repopulation and IL-1-like bioactivity in the seminiferous epithelium. DNA s... | 10.1111/j.1365-2605.1993.tb01170.x | 8,514,429 | D000818:Animals; D046508:Culture Techniques; D004247:DNA; D004260:DNA Repair; D006133:Growth Substances; D007375:Interleukin-1; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D013091:Spermatogenesis; D013737:Testis; D013936:Thymidine | International journal of andrology | 1,993 | D006133:Growth Substances; D007375:Interleukin-1; D004247:DNA; D013936:Thymidine |
Comparison of phenothrin shampoo and malathion lotion in the treatment of head louse infection. | Eighty patients (age range 4-10 years) with head lice infection were recruited to the study. Forty patients were treated with a single application of 0.2% w/v phenothrin liquid shampoo and 40 with 0.2% w/v malathion lotion. Inspection of the patients one week later revealed that no live lice remained in either group, b... | 10.1177/146642409011000210 | 2,110,262 | D000287:Administration, Topical; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007306:Insecticides; D010373:Lice Infestations; D008294:Malathion; D008297:Male; D010270:Parasite Egg Count; D011722:Pyrethrins; D012008:Recurrence; D012535:Scalp | Journal of the Royal Society of Health | 1,990 | D007306:Insecticides; D011722:Pyrethrins; C006166:phenothrin; D008294:Malathion |
A recyclable nanosheet of Mo/N-doped TiO2 nanorods decorated on carbon nanofibers for organic pollutants degradation under simulated sunlight irradiation. | A novel nanosheet of Mo/N-codoped TiO2 nanorods immobilized on carbon nanofibers (MNTC nanosheet) was self-synthesized through two facile steps. The Mo/N-doped TiO2 nanorods dispersed through in situ growth on the network constructed by long and vertical carbon nanofibers (CNFs). The fabricated MNTC nanosheet displayed... | 10.1016/j.chemosphere.2018.09.182 | 30,321,808 | D001559:Benzhydryl Compounds; D002244:Carbon; D002384:Catalysis; D052918:Environmental Restoration and Remediation; D008751:Methylene Blue; D057139:Nanofibers; D053758:Nanoparticles; D043942:Nanotubes; D009930:Organic Chemicals; D010636:Phenols; D059027:Recycling; D013472:Sunlight; D014025:Titanium; D018508:Water Purif... | Chemosphere | 2,019 | D001559:Benzhydryl Compounds; D009930:Organic Chemicals; D010636:Phenols; C009495:titanium dioxide; D002244:Carbon; D014025:Titanium; C006780:bisphenol A; D008751:Methylene Blue |
Novel frontiers in calcium signaling: A possible target for chemotherapy. | Intracellular calcium (Ca(2+)) is largely known as a second messenger that is able to drive effects ranging from vesicle formation to muscle contraction, energy production and much more. In spite of its physiological regulation, Ca(2+) is a strategic tool for regulating apoptosis, especially during transmission between... | 26,028,552 | D000818:Animals; D017209:Apoptosis; D020013:Calcium Signaling; D055808:Drug Discovery; D006801:Humans; D008954:Models, Biological; D058990:Molecular Targeted Therapy; D009369:Neoplasms; D010778:Photochemotherapy; D016159:Tumor Suppressor Protein p53 | Pharmacological research | 2,015 | D016159:Tumor Suppressor Protein p53 | |
Ear tuftedness: a lethal condition in the Araucana fowl. | The lethal effects of the ear-tuft trait of the Araucana chicken are reported and the genetic basis of its inheritance is verified. The ear-tuft (Et) gene acts as an autosomal dominant with reduced penetrance in heterozygotes. This study gave two estimates of reduced penetrance, 4 and 14 percent. Homozygotes die during... | 10.1093/oxfordjournals.jhered.a109439 | 7,276,512 | D000818:Animals; D002645:Chickens; D005786:Gene Expression Regulation; D005799:Genes, Dominant; D005804:Genes, Lethal; D006579:Heterozygote; D006720:Homozygote | The Journal of heredity | 1,981 | |
Improving the reliability of the auditory middle latency response by monitoring EEG delta activity. | The auditory middle latency response (MLR), a useful tool in the assessment of low-frequency auditory sensitivity, can be consistently recorded in young children during wakefulness, stages 1 and 2, and REM sleep. Responses are often absent or questionable during stage 4. An on-line measure indicating favorable periods ... | 10.1097/00003446-199304000-00002 | 8,472,881 | D000161:Acoustic Stimulation; D001307:Auditory Perception; D002648:Child; D002675:Child, Preschool; D003700:Delta Rhythm; D004569:Electroencephalography; D016057:Evoked Potentials, Auditory, Brain Stem; D005260:Female; D006801:Humans; D008297:Male; D012895:Sleep, REM; D014851:Wakefulness | Ear and hearing | 1,993 |
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